4Q3QA

Crystal structure of schistosoma mansoni arginase in complex with inhibitor abh
Total Genus 127
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
344
structure length
335
Chain Sequence
KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Schistosoma mansoni
molecule keywords Arginase
total genus 127
structure length 335
sequence length 344
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q3qA00
2A0MA 4Q3RA 4GWCA 3GN0A 4RHMA 4RHIA 3LP7A 4GSVA 1HQGA 3MMRA 3SL0A 1CEVA 1P8OA 1WOHA 5HJAA 3NIOA 4IU1A 3LHLA 1ZPGA 4GSZA 2AEBA 1TBJA 4IXUA 4Q3VA 4Q41A 4GWDA 4RHLA 5HJ9A 4Q3TA 1P8RA 3SKKA 3THEA 3KV2A 1T4TA 3MFVA 2PHAA 4HXQA 4IE3A 2ZAVA 4Q3UA 3NIQA 1P8MA 4HZEA 3RLAA 1HQXA 4DZ4A 3SJTA 2PHOA 1T5GA 1P8PA 1P8NA 1T4RA 4FCIA 4GSMA 4MYNA 3NIPA 2CEVA 3E8ZA 4IE2A 4IU0A 1GQ6A 1TBLA 3M1RA 3GMZA 2RLAA 5CEVA 1T4SA 3TH7A 1D3VA 4RLAA 1WVAA 1XFKA 1HQHA 5RLAA 4FCKA 4IU5A 3TF3A 1RLAA 1PQ3A 4Q3SA 3THHA 4RHQA 3SL1A 3THJA 1WOGA 3E9BA 1HQ5A 1TBHA 1R1OA 4Q3QA 4MYKA 1P8QA 4MXRA 4RHJA 1P8SA 4Q3RC 3CEVA 4HWWA 1HQFA 3DJ8A 1WOIA 3MFWA 4MYFA 2EF5A 4IE1A 2EIVA 4I06A 1GQ7A 1ZPEA 4CEVA 4Q3PA 1TA1A 3E6KA 1T4PA 3MJLA 3F80A 3E8QA 4IXVA 2EF4A 2PLLA 4Q40A 1WVBA 1T5FA 4ITYA 3E6VA 4Q42A 4IU4A 3LP4A 4G3HA 4RHKA 4MYLA 3PZLA
chains in the Genus database with same CATH superfamily
5ICNB 5G0XA 2A0MA 4QA3A 5D1BA 4Q3RA 4BZ8A 4GWCA 1C3PA 1ZZ0A 3EZTA 4ZUOA 5EEKA 3GN0A 4RHMA 4RHIA 3C0YA 3LP7A 4BZ5A 3Q9FA 4GSVA 1HQGA 1T69A 2VCGA 3EWFA 1T64A 3MMRA 5G1BA 4CQFA 3SL0A 1CEVA 1P8OA 5FUEA 3ZNRA 1WOHA 3MENA 5HJAA 3MZ6A 2VQQA 3NIOA 4IU1A 3LHLA 3F06A 5LI3A 1ZPGA 4LY1A 2V5WA 4GSZA 2AEBA 1TBJA 4IXUA 3Q9BA 4Q3VA 3MAXA 4RN0A 5G0IA 4Q41A 4GWDA 4RHLA 5HJ9A 4Q3TA 5G1CA 5G10A 1P8RA 3SKKA 3THEA 3KV2A 5EFGA 5EFBD 1T4TA 5DC6A 3ZNSA 3F0RA 2PHAA 3MFVA 4HXQA 1VKGA 5G11A 4IE3A 2ZAVA 4Q3UA 3NIQA 1P8MA 3MZ7A 4HZEA 5EEMA 5DC8A 3RLAA 1W22A 5G0YA 5THVA 1HQXA 3MZ4A 2VQOA 2VQVA 2VQWG 4DZ4A 5JI5A 3SJTA 4BZ7A 3SFHA 2PHOA 1T5GA 4ZUQA 3F07A 2VQJA 5G0JA 1P8PA 4CBTA 5EEFA 1P8NA 1T4RA 4FCIA 4GSMA 4MYNA 4QA5A 3NIPA 5EEIA 2CEVA 3C10A 3E8ZA 4IE2A 4IU0A 1GQ6A 2VQMA 1TBLA 3M1RA 4ZUMA 3C0ZA 3GMZA 3SFFA 2RLAA 5CEVA 4QA1A 1C3SA 1T4SA 5IX0A 1ZZ1A 3TH7A 4A69A 1D3VA 4RLAA 1WVAA 4LXZA 1XFKA 1HQHA 4CBYA 4QA0A 5RLAA 4FCKA 4IU5A 3TF3A 1RLAA 1PQ3A 4Q3SA 4ZUNA 4ZUPA 3THHA 4RHQA 3RQDA 2V5XA 4QA7A 3SL1A 3THJA 1WOGA 3EW8A 3E9BA 2GH6A 4ZURA 1HQ5A 1TBHA 5A2SA 1R1OA 4Q3QA 5D1CA 4MYKA 3Q9CA 4QA6A 5EFHA 1P8QA 4MXRA 4RHJA 5EFNA 5G12A 3EZPA 5DC7A 5D1DA 1P8SA 4Q3RC 3CEVA 4HWWA 4RN1A 1HQFA 5EF8A 4BZ9A 3DJ8A 1WOIA 5THTA 3MFWA 4MYFA 5G13A 5IWGA 5G1AA 2EF5A 4IE1A 2EIVA 4MYLA 5EENA 5THSA 3Q9EA 4I06A 5G0GA 5EF7A 5FCWA 1GQ7A 1ZZ3A 4BKXB 1ZPEA 4CEVA 4Q3PA 4BZ6A 1TA1A 3E6KA 1T4PA 3MJLA 3F80A 1T67A 5DC5A 3E8QA 4IXVA 5EFKB 5G17A 4RN2A 2EF4A 5EFJD 2PLLA 4QA2A 1C3RA 4Q40A 5G0HA 5BWZA 1WVBA 5G3WA 1T5FA 5THUA 4ITYA 3E6VA 4Q42A 4IU4A 4QA4A 3LP4A 4G3HA 4RHKA 3MZ3A 3PZLA
chains in the Genus database with same CATH topology
2A0MA 4Q3RA 4GWCA 3GN0A 4RHMA 4RHIA 3LP7A 4GSVA 1HQGA 3MMRA 3SL0A 1CEVA 1P8OA 1WOHA 5HJAA 3NIOA 4IU1A 3LHLA 1ZPGA 4GSZA 2AEBA 1TBJA 4IXUA 4Q3VA 4Q41A 4GWDA 4RHLA 5HJ9A 4Q3TA 1P8RA 3SKKA 3THEA 3KV2A 1T4TA 3MFVA 2PHAA 4HXQA 4IE3A 2ZAVA 4Q3UA 3NIQA 1P8MA 4HZEA 3RLAA 1HQXA 4DZ4A 3SJTA 2PHOA 1T5GA 1P8PA 1P8NA 1T4RA 4FCIA 4GSMA 4MYNA 3NIPA 2CEVA 3E8ZA 4IE2A 4IU0A 1GQ6A 1TBLA 3M1RA 3GMZA 2RLAA 5CEVA 1T4SA 3TH7A 1D3VA 4RLAA 1WVAA 1XFKA 1HQHA 5RLAA 4FCKA 4IU5A 3TF3A 1RLAA 1PQ3A 4Q3SA 3THHA 4RHQA 3SL1A 3THJA 1WOGA 3E9BA 1HQ5A 1TBHA 1R1OA 4Q3QA 4MYKA 1P8QA 4MXRA 4RHJA 1P8SA 4Q3RC 3CEVA 4HWWA 1HQFA 3DJ8A 1WOIA 3MFWA 4MYFA 2EF5A 4IE1A 2EIVA 4I06A 1GQ7A 1ZPEA 4CEVA 4Q3PA 1TA1A 3E6KA 1T4PA 3MJLA 3F80A 3E8QA 4IXVA 2EF4A 2PLLA 4Q40A 1WVBA 1T5FA 4ITYA 3E6VA 4Q42A 4IU4A 3LP4A 4G3HA 4RHKA 4MYLA 3PZLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A0M A;  4Q3R A;  4GWC A;  3GN0 A;  4RHM A;  4RHI A;  3LP7 A;  4GSV A;  1HQG A;  3MMR A;  3SL0 A;  1CEV A;  1P8O A;  1WOH A;  5HJA A;  3NIO A;  4IU1 A;  3LHL A;  1ZPG A;  4GSZ A;  2AEB A;  1TBJ A;  4IXU A;  4Q3V A;  4Q41 A;  4GWD A;  4RHL A;  5HJ9 A;  4Q3T A;  1P8R A;  3SKK A;  3THE A;  3KV2 A;  1T4T A;  3MFV A;  2PHA A;  4HXQ A;  4IE3 A;  2ZAV A;  4Q3U A;  3NIQ A;  1P8M A;  4HZE A;  3RLA A;  1HQX A;  4DZ4 A;  3SJT A;  2PHO A;  1T5G A;  1P8P A;  1P8N A;  1T4R A;  4FCI A;  4GSM A;  4MYN A;  3NIP A;  2CEV A;  3E8Z A;  4IE2 A;  4IU0 A;  1GQ6 A;  1TBL A;  3M1R A;  3GMZ A;  2RLA A;  5CEV A;  1T4S A;  3TH7 A;  1D3V A;  4RLA A;  1WVA A;  1XFK A;  1HQH A;  5RLA A;  4FCK A;  4IU5 A;  3TF3 A;  1RLA A;  1PQ3 A;  4Q3S A;  3THH A;  4RHQ A;  3SL1 A;  3THJ A;  1WOG A;  3E9B A;  1HQ5 A;  1TBH A;  1R1O A;  4Q3Q A;  4MYK A;  1P8Q A;  4MXR A;  4RHJ A;  1P8S A;  4Q3R C;  3CEV A;  4HWW A;  1HQF A;  3DJ8 A;  1WOI A;  3MFW A;  4MYF A;  2EF5 A;  4IE1 A;  2EIV A;  4I06 A;  1GQ7 A;  1ZPE A;  4CEV A;  4Q3P A;  1TA1 A;  3E6K A;  1T4P A;  3MJL A;  3F80 A;  3E8Q A;  4IXV A;  2EF4 A;  2PLL A;  4Q40 A;  1WVB A;  1T5F A;  4ITY A;  3E6V A;  4Q42 A;  4IU4 A;  3LP4 A;  4G3H A;  4RHK A;  4MYL A;  3PZL A; 
#chains in the Genus database with same CATH topology
 5ICN B;  5G0X A;  2A0M A;  4QA3 A;  5D1B A;  4Q3R A;  4BZ8 A;  4GWC A;  1C3P A;  1ZZ0 A;  3EZT A;  4ZUO A;  5EEK A;  3GN0 A;  4RHM A;  4RHI A;  3C0Y A;  3LP7 A;  4BZ5 A;  3Q9F A;  4GSV A;  1HQG A;  1T69 A;  2VCG A;  3EWF A;  1T64 A;  3MMR A;  5G1B A;  4CQF A;  3SL0 A;  1CEV A;  1P8O A;  5FUE A;  3ZNR A;  1WOH A;  3MEN A;  5HJA A;  3MZ6 A;  2VQQ A;  3NIO A;  4IU1 A;  3LHL A;  3F06 A;  5LI3 A;  1ZPG A;  4LY1 A;  2V5W A;  4GSZ A;  2AEB A;  1TBJ A;  4IXU A;  3Q9B A;  4Q3V A;  3MAX A;  4RN0 A;  5G0I A;  4Q41 A;  4GWD A;  4RHL A;  5HJ9 A;  4Q3T A;  5G1C A;  5G10 A;  1P8R A;  3SKK A;  3THE A;  3KV2 A;  5EFG A;  5EFB D;  1T4T A;  5DC6 A;  3ZNS A;  3F0R A;  2PHA A;  3MFV A;  4HXQ A;  1VKG A;  5G11 A;  4IE3 A;  2ZAV A;  4Q3U A;  3NIQ A;  1P8M A;  3MZ7 A;  4HZE A;  5EEM A;  5DC8 A;  3RLA A;  1W22 A;  5G0Y A;  5THV A;  1HQX A;  3MZ4 A;  2VQO A;  2VQV A;  2VQW G;  4DZ4 A;  5JI5 A;  3SJT A;  4BZ7 A;  3SFH A;  2PHO A;  1T5G A;  4ZUQ A;  3F07 A;  2VQJ A;  5G0J A;  1P8P A;  4CBT A;  5EEF A;  1P8N A;  1T4R A;  4FCI A;  4GSM A;  4MYN A;  4QA5 A;  3NIP A;  5EEI A;  2CEV A;  3C10 A;  3E8Z A;  4IE2 A;  4IU0 A;  1GQ6 A;  2VQM A;  1TBL A;  3M1R A;  4ZUM A;  3C0Z A;  3GMZ A;  3SFF A;  2RLA A;  5CEV A;  4QA1 A;  1C3S A;  1T4S A;  5IX0 A;  1ZZ1 A;  3TH7 A;  4A69 A;  1D3V A;  4RLA A;  1WVA A;  4LXZ A;  1XFK A;  1HQH A;  4CBY A;  4QA0 A;  5RLA A;  4FCK A;  4IU5 A;  3TF3 A;  1RLA A;  1PQ3 A;  4Q3S A;  4ZUN A;  4ZUP A;  3THH A;  4RHQ A;  3RQD A;  2V5X A;  4QA7 A;  3SL1 A;  3THJ A;  1WOG A;  3EW8 A;  3E9B A;  2GH6 A;  4ZUR A;  1HQ5 A;  1TBH A;  5A2S A;  1R1O A;  4Q3Q A;  5D1C A;  4MYK A;  3Q9C A;  4QA6 A;  5EFH A;  1P8Q A;  4MXR A;  4RHJ A;  5EFN A;  5G12 A;  3EZP A;  5DC7 A;  5D1D A;  1P8S A;  4Q3R C;  3CEV A;  4HWW A;  4RN1 A;  1HQF A;  5EF8 A;  4BZ9 A;  3DJ8 A;  1WOI A;  5THT A;  3MFW A;  4MYF A;  5G13 A;  5IWG A;  5G1A A;  2EF5 A;  4IE1 A;  2EIV A;  4MYL A;  5EEN A;  5THS A;  3Q9E A;  4I06 A;  5G0G A;  5EF7 A;  5FCW A;  1GQ7 A;  1ZZ3 A;  4BKX B;  1ZPE A;  4CEV A;  4Q3P A;  4BZ6 A;  1TA1 A;  3E6K A;  1T4P A;  3MJL A;  3F80 A;  1T67 A;  5DC5 A;  3E8Q A;  4IXV A;  5EFK B;  5G17 A;  4RN2 A;  2EF4 A;  5EFJ D;  2PLL A;  4QA2 A;  1C3R A;  4Q40 A;  5G0H A;  5BWZ A;  1WVB A;  5G3W A;  1T5F A;  5THU A;  4ITY A;  3E6V A;  4Q42 A;  4IU4 A;  4QA4 A;  3LP4 A;  4G3H A;  4RHK A;  3MZ3 A;  3PZL A; 
#chains in the Genus database with same CATH homology
 2A0M A;  4Q3R A;  4GWC A;  3GN0 A;  4RHM A;  4RHI A;  3LP7 A;  4GSV A;  1HQG A;  3MMR A;  3SL0 A;  1CEV A;  1P8O A;  1WOH A;  5HJA A;  3NIO A;  4IU1 A;  3LHL A;  1ZPG A;  4GSZ A;  2AEB A;  1TBJ A;  4IXU A;  4Q3V A;  4Q41 A;  4GWD A;  4RHL A;  5HJ9 A;  4Q3T A;  1P8R A;  3SKK A;  3THE A;  3KV2 A;  1T4T A;  3MFV A;  2PHA A;  4HXQ A;  4IE3 A;  2ZAV A;  4Q3U A;  3NIQ A;  1P8M A;  4HZE A;  3RLA A;  1HQX A;  4DZ4 A;  3SJT A;  2PHO A;  1T5G A;  1P8P A;  1P8N A;  1T4R A;  4FCI A;  4GSM A;  4MYN A;  3NIP A;  2CEV A;  3E8Z A;  4IE2 A;  4IU0 A;  1GQ6 A;  1TBL A;  3M1R A;  3GMZ A;  2RLA A;  5CEV A;  1T4S A;  3TH7 A;  1D3V A;  4RLA A;  1WVA A;  1XFK A;  1HQH A;  5RLA A;  4FCK A;  4IU5 A;  3TF3 A;  1RLA A;  1PQ3 A;  4Q3S A;  3THH A;  4RHQ A;  3SL1 A;  3THJ A;  1WOG A;  3E9B A;  1HQ5 A;  1TBH A;  1R1O A;  4Q3Q A;  4MYK A;  1P8Q A;  4MXR A;  4RHJ A;  1P8S A;  4Q3R C;  3CEV A;  4HWW A;  1HQF A;  3DJ8 A;  1WOI A;  3MFW A;  4MYF A;  2EF5 A;  4IE1 A;  2EIV A;  4I06 A;  1GQ7 A;  1ZPE A;  4CEV A;  4Q3P A;  1TA1 A;  3E6K A;  1T4P A;  3MJL A;  3F80 A;  3E8Q A;  4IXV A;  2EF4 A;  2PLL A;  4Q40 A;  1WVB A;  1T5F A;  4ITY A;  3E6V A;  4Q42 A;  4IU4 A;  3LP4 A;  4G3H A;  4RHK A;  4MYL A;  3PZL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...