4Q41A

Crystal structure of schistosoma mansoni arginase in complex with l-lysine
Total Genus 125
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
344
structure length
333
Chain Sequence
KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Schistosoma mansoni
molecule keywords Arginase
total genus 125
structure length 333
sequence length 344
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q41A00
4FCIA 1TBJA 4MYFA 3THHA 3NIOA 4Q3UA 1WOIA 4Q3QA 3SJTA 1D3VA 1P8OA 4MXRA 3GN0A 2PLLA 4GWCA 4RHMA 2A0MA 4IU5A 3NIQA 3LP4A 4Q3TA 1T4SA 4CEVA 1T4PA 1P8RA 1ZPEA 5RLAA 3LP7A 4HZEA 4Q3RA 4MYNA 4IE3A 4G3HA 1WOGA 1HQGA 3E6VA 4Q3VA 4RHIA 3RLAA 1HQ5A 1P8PA 4Q40A 3TH7A 1HQXA 4DZ4A 2EF4A 5HJAA 4RHLA 1P8MA 1TBHA 1GQ7A 3SL0A 3LHLA 3M1RA 1TA1A 1CEVA 3MFWA 4GSZA 3MJLA 4RHJA 1T5FA 1P8QA 4HXQA 1T5GA 3E9BA 3SKKA 4FCKA 3THJA 3DJ8A 4IE1A 2RLAA 4IE2A 1RLAA 4I06A 3NIPA 1HQHA 1T4RA 4MYLA 3SL1A 4Q3PA 3E6KA 2PHAA 5HJ9A 1WVBA 4ITYA 3CEVA 4Q3SA 3MFVA 5CEVA 4RHKA 1ZPGA 4GSMA 2CEVA 1GQ6A 1PQ3A 3KV2A 3MMRA 4RHQA 4RLAA 4MYKA 4IXUA 1WOHA 4IU4A 4IU1A 3GMZA 1XFKA 3THEA 3E8QA 1P8NA 1TBLA 1WVAA 1T4TA 4HWWA 2AEBA 4Q42A 3TF3A 1R1OA 4IU0A 3F80A 4GSVA 2PHOA 4Q41A 2EF5A 2ZAVA 2EIVA 3PZLA 3E8ZA 1HQFA 4IXVA 4Q3RC 1P8SA 4GWDA
chains in the Genus database with same CATH superfamily
4FCIA 1TBJA 4MYFA 2V5WA 3THHA 5THSA 3ZNRA 3NIOA 5EFNA 3F07A 4Q3UA 1WOIA 4Q3QA 3SJTA 5BWZA 5DC5A 1D3VA 4BKXB 1P8OA 4MXRA 3GN0A 2PLLA 3Q9FA 4QA6A 4GWCA 2VQJA 5EENA 5A2SA 5D1CA 5JI5A 4RHMA 3Q9EA 1VKGA 2A0MA 4IU5A 3NIQA 3LP4A 4Q3TA 1T4SA 4CEVA 1T4PA 1P8RA 1ZPEA 4QA2A 5G1CA 5DC7A 3EZPA 1C3PA 5RLAA 5G3WA 3LP7A 1W22A 1ZZ1A 4HZEA 4Q3RA 4MYNA 4IE3A 4G3HA 5G13A 1WOGA 5LI3A 5IWGA 4RN2A 1HQGA 3E6VA 4Q3VA 4QA1A 4RHIA 1HQ5A 1P8PA 3MZ6A 3RLAA 4Q40A 3EW8A 3TH7A 1HQXA 5G10A 5EFGA 4DZ4A 2EF4A 5G0GA 3F0RA 4CQFA 4QA5A 5FCWA 5HJAA 4RHLA 1P8MA 1TBHA 1GQ7A 5G17A 3SL0A 5EF8A 5G0JA 3LHLA 3M1RA 1TA1A 1CEVA 3MFWA 4GSZA 4LXZA 5G0HA 3MJLA 3Q9BA 4RHJA 1T5FA 3F06A 1P8QA 5G12A 1T69A 4HXQA 1T5GA 2GH6A 3E9BA 5D1BA 5EEMA 3Q9CA 3EWFA 4RN0A 5EFHA 2VQOA 4BZ8A 5G1AA 3SKKA 4FCKA 3MZ7A 3THJA 3MENA 5FUEA 5EEIA 3DJ8A 4IE1A 3MZ4A 4BZ9A 4ZUNA 2VQWG 2RLAA 4CBTA 4IE2A 1C3RA 2VQMA 4QA0A 3C10A 3EZTA 3MZ3A 1RLAA 3MAXA 4QA3A 4I06A 3ZNSA 3NIPA 1HQHA 1T4RA 4MYLA 5EEFA 3SL1A 4QA7A 5EEKA 4Q3PA 3E6KA 5G1BA 2PHAA 3SFHA 5EFBD 5HJ9A 1WVBA 5DC8A 4ITYA 3C0YA 3CEVA 4Q3SA 3MFVA 5D1DA 4ZUQA 5CEVA 4RHKA 5THVA 5THTA 1ZPGA 4GSMA 2CEVA 5ICNB 2VCGA 5G0YA 1GQ6A 4CBYA 2VQVA 1PQ3A 3KV2A 3MMRA 4ZUPA 4RHQA 4RLAA 5EFJD 4MYKA 4IXUA 5EFKB 1WOHA 4IU4A 4IU1A 5G0XA 3GMZA 1T67A 1T64A 1XFKA 3THEA 4BZ7A 4BZ5A 4BZ6A 3E8QA 1P8NA 1TBLA 1WVAA 1T4TA 4HWWA 1ZZ3A 4ZUOA 2AEBA 3C0ZA 2V5XA 4Q42A 4A69A 3TF3A 5THUA 1R1OA 4IU0A 3F80A 4GSVA 5EF7A 2PHOA 5G0IA 4ZURA 3SFFA 4RN1A 5G11A 4Q41A 2ZAVA 2EF5A 2EIVA 1C3SA 1ZZ0A 2VQQA 3PZLA 4ZUMA 3E8ZA 1HQFA 4IXVA 4Q3RC 1P8SA 5DC6A 4QA4A 3RQDA 5IX0A 4LY1A 4GWDA
chains in the Genus database with same CATH topology
4FCIA 1TBJA 4MYFA 3THHA 3NIOA 4Q3UA 1WOIA 4Q3QA 3SJTA 1D3VA 1P8OA 4MXRA 3GN0A 2PLLA 4GWCA 4RHMA 2A0MA 4IU5A 3NIQA 3LP4A 4Q3TA 1T4SA 4CEVA 1T4PA 1P8RA 1ZPEA 5RLAA 3LP7A 4HZEA 4Q3RA 4MYNA 4IE3A 4G3HA 1WOGA 1HQGA 3E6VA 4Q3VA 4RHIA 3RLAA 1HQ5A 1P8PA 4Q40A 3TH7A 1HQXA 4DZ4A 2EF4A 5HJAA 4RHLA 1P8MA 1TBHA 1GQ7A 3SL0A 3LHLA 3M1RA 1TA1A 1CEVA 3MFWA 4GSZA 3MJLA 4RHJA 1T5FA 1P8QA 4HXQA 1T5GA 3E9BA 3SKKA 4FCKA 3THJA 3DJ8A 4IE1A 2RLAA 4IE2A 1RLAA 4I06A 3NIPA 1HQHA 1T4RA 4MYLA 3SL1A 4Q3PA 3E6KA 2PHAA 5HJ9A 1WVBA 4ITYA 3CEVA 4Q3SA 3MFVA 5CEVA 4RHKA 1ZPGA 4GSMA 2CEVA 1GQ6A 1PQ3A 3KV2A 3MMRA 4RHQA 4RLAA 4MYKA 4IXUA 1WOHA 4IU4A 4IU1A 3GMZA 1XFKA 3THEA 3E8QA 1P8NA 1TBLA 1WVAA 1T4TA 4HWWA 2AEBA 4Q42A 3TF3A 1R1OA 4IU0A 3F80A 4GSVA 2PHOA 4Q41A 2EF5A 2ZAVA 2EIVA 3PZLA 3E8ZA 1HQFA 4IXVA 4Q3RC 1P8SA 4GWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FCI A;  1TBJ A;  4MYF A;  3THH A;  3NIO A;  4Q3U A;  1WOI A;  4Q3Q A;  3SJT A;  1D3V A;  1P8O A;  4MXR A;  3GN0 A;  2PLL A;  4GWC A;  4RHM A;  2A0M A;  4IU5 A;  3NIQ A;  3LP4 A;  4Q3T A;  1T4S A;  4CEV A;  1T4P A;  1P8R A;  1ZPE A;  5RLA A;  3LP7 A;  4HZE A;  4Q3R A;  4MYN A;  4IE3 A;  4G3H A;  1WOG A;  1HQG A;  3E6V A;  4Q3V A;  4RHI A;  3RLA A;  1HQ5 A;  1P8P A;  4Q40 A;  3TH7 A;  1HQX A;  4DZ4 A;  2EF4 A;  5HJA A;  4RHL A;  1P8M A;  1TBH A;  1GQ7 A;  3SL0 A;  3LHL A;  3M1R A;  1TA1 A;  1CEV A;  3MFW A;  4GSZ A;  3MJL A;  4RHJ A;  1T5F A;  1P8Q A;  4HXQ A;  1T5G A;  3E9B A;  3SKK A;  4FCK A;  3THJ A;  3DJ8 A;  4IE1 A;  2RLA A;  4IE2 A;  1RLA A;  4I06 A;  3NIP A;  1HQH A;  1T4R A;  4MYL A;  3SL1 A;  4Q3P A;  3E6K A;  2PHA A;  5HJ9 A;  1WVB A;  4ITY A;  3CEV A;  4Q3S A;  3MFV A;  5CEV A;  4RHK A;  1ZPG A;  4GSM A;  2CEV A;  1GQ6 A;  1PQ3 A;  3KV2 A;  3MMR A;  4RHQ A;  4RLA A;  4MYK A;  4IXU A;  1WOH A;  4IU4 A;  4IU1 A;  3GMZ A;  1XFK A;  3THE A;  3E8Q A;  1P8N A;  1TBL A;  1WVA A;  1T4T A;  4HWW A;  2AEB A;  4Q42 A;  3TF3 A;  1R1O A;  4IU0 A;  3F80 A;  4GSV A;  2PHO A;  4Q41 A;  2EF5 A;  2ZAV A;  2EIV A;  3PZL A;  3E8Z A;  1HQF A;  4IXV A;  4Q3R C;  1P8S A;  4GWD A; 
#chains in the Genus database with same CATH topology
 4FCI A;  1TBJ A;  4MYF A;  2V5W A;  3THH A;  5THS A;  3ZNR A;  3NIO A;  5EFN A;  3F07 A;  4Q3U A;  1WOI A;  4Q3Q A;  3SJT A;  5BWZ A;  5DC5 A;  1D3V A;  4BKX B;  1P8O A;  4MXR A;  3GN0 A;  2PLL A;  3Q9F A;  4QA6 A;  4GWC A;  2VQJ A;  5EEN A;  5A2S A;  5D1C A;  5JI5 A;  4RHM A;  3Q9E A;  1VKG A;  2A0M A;  4IU5 A;  3NIQ A;  3LP4 A;  4Q3T A;  1T4S A;  4CEV A;  1T4P A;  1P8R A;  1ZPE A;  4QA2 A;  5G1C A;  5DC7 A;  3EZP A;  1C3P A;  5RLA A;  5G3W A;  3LP7 A;  1W22 A;  1ZZ1 A;  4HZE A;  4Q3R A;  4MYN A;  4IE3 A;  4G3H A;  5G13 A;  1WOG A;  5LI3 A;  5IWG A;  4RN2 A;  1HQG A;  3E6V A;  4Q3V A;  4QA1 A;  4RHI A;  1HQ5 A;  1P8P A;  3MZ6 A;  3RLA A;  4Q40 A;  3EW8 A;  3TH7 A;  1HQX A;  5G10 A;  5EFG A;  4DZ4 A;  2EF4 A;  5G0G A;  3F0R A;  4CQF A;  4QA5 A;  5FCW A;  5HJA A;  4RHL A;  1P8M A;  1TBH A;  1GQ7 A;  5G17 A;  3SL0 A;  5EF8 A;  5G0J A;  3LHL A;  3M1R A;  1TA1 A;  1CEV A;  3MFW A;  4GSZ A;  4LXZ A;  5G0H A;  3MJL A;  3Q9B A;  4RHJ A;  1T5F A;  3F06 A;  1P8Q A;  5G12 A;  1T69 A;  4HXQ A;  1T5G A;  2GH6 A;  3E9B A;  5D1B A;  5EEM A;  3Q9C A;  3EWF A;  4RN0 A;  5EFH A;  2VQO A;  4BZ8 A;  5G1A A;  3SKK A;  4FCK A;  3MZ7 A;  3THJ A;  3MEN A;  5FUE A;  5EEI A;  3DJ8 A;  4IE1 A;  3MZ4 A;  4BZ9 A;  4ZUN A;  2VQW G;  2RLA A;  4CBT A;  4IE2 A;  1C3R A;  2VQM A;  4QA0 A;  3C10 A;  3EZT A;  3MZ3 A;  1RLA A;  3MAX A;  4QA3 A;  4I06 A;  3ZNS A;  3NIP A;  1HQH A;  1T4R A;  4MYL A;  5EEF A;  3SL1 A;  4QA7 A;  5EEK A;  4Q3P A;  3E6K A;  5G1B A;  2PHA A;  3SFH A;  5EFB D;  5HJ9 A;  1WVB A;  5DC8 A;  4ITY A;  3C0Y A;  3CEV A;  4Q3S A;  3MFV A;  5D1D A;  4ZUQ A;  5CEV A;  4RHK A;  5THV A;  5THT A;  1ZPG A;  4GSM A;  2CEV A;  5ICN B;  2VCG A;  5G0Y A;  1GQ6 A;  4CBY A;  2VQV A;  1PQ3 A;  3KV2 A;  3MMR A;  4ZUP A;  4RHQ A;  4RLA A;  5EFJ D;  4MYK A;  4IXU A;  5EFK B;  1WOH A;  4IU4 A;  4IU1 A;  5G0X A;  3GMZ A;  1T67 A;  1T64 A;  1XFK A;  3THE A;  4BZ7 A;  4BZ5 A;  4BZ6 A;  3E8Q A;  1P8N A;  1TBL A;  1WVA A;  1T4T A;  4HWW A;  1ZZ3 A;  4ZUO A;  2AEB A;  3C0Z A;  2V5X A;  4Q42 A;  4A69 A;  3TF3 A;  5THU A;  1R1O A;  4IU0 A;  3F80 A;  4GSV A;  5EF7 A;  2PHO A;  5G0I A;  4ZUR A;  3SFF A;  4RN1 A;  5G11 A;  4Q41 A;  2ZAV A;  2EF5 A;  2EIV A;  1C3S A;  1ZZ0 A;  2VQQ A;  3PZL A;  4ZUM A;  3E8Z A;  1HQF A;  4IXV A;  4Q3R C;  1P8S A;  5DC6 A;  4QA4 A;  3RQD A;  5IX0 A;  4LY1 A;  4GWD A; 
#chains in the Genus database with same CATH homology
 4FCI A;  1TBJ A;  4MYF A;  3THH A;  3NIO A;  4Q3U A;  1WOI A;  4Q3Q A;  3SJT A;  1D3V A;  1P8O A;  4MXR A;  3GN0 A;  2PLL A;  4GWC A;  4RHM A;  2A0M A;  4IU5 A;  3NIQ A;  3LP4 A;  4Q3T A;  1T4S A;  4CEV A;  1T4P A;  1P8R A;  1ZPE A;  5RLA A;  3LP7 A;  4HZE A;  4Q3R A;  4MYN A;  4IE3 A;  4G3H A;  1WOG A;  1HQG A;  3E6V A;  4Q3V A;  4RHI A;  3RLA A;  1HQ5 A;  1P8P A;  4Q40 A;  3TH7 A;  1HQX A;  4DZ4 A;  2EF4 A;  5HJA A;  4RHL A;  1P8M A;  1TBH A;  1GQ7 A;  3SL0 A;  3LHL A;  3M1R A;  1TA1 A;  1CEV A;  3MFW A;  4GSZ A;  3MJL A;  4RHJ A;  1T5F A;  1P8Q A;  4HXQ A;  1T5G A;  3E9B A;  3SKK A;  4FCK A;  3THJ A;  3DJ8 A;  4IE1 A;  2RLA A;  4IE2 A;  1RLA A;  4I06 A;  3NIP A;  1HQH A;  1T4R A;  4MYL A;  3SL1 A;  4Q3P A;  3E6K A;  2PHA A;  5HJ9 A;  1WVB A;  4ITY A;  3CEV A;  4Q3S A;  3MFV A;  5CEV A;  4RHK A;  1ZPG A;  4GSM A;  2CEV A;  1GQ6 A;  1PQ3 A;  3KV2 A;  3MMR A;  4RHQ A;  4RLA A;  4MYK A;  4IXU A;  1WOH A;  4IU4 A;  4IU1 A;  3GMZ A;  1XFK A;  3THE A;  3E8Q A;  1P8N A;  1TBL A;  1WVA A;  1T4T A;  4HWW A;  2AEB A;  4Q42 A;  3TF3 A;  1R1O A;  4IU0 A;  3F80 A;  4GSV A;  2PHO A;  4Q41 A;  2EF5 A;  2ZAV A;  2EIV A;  3PZL A;  3E8Z A;  1HQF A;  4IXV A;  4Q3R C;  1P8S A;  4GWD A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...