5G3WA

Structure of hdac like protein from bordetella alcaligenes in complex with the photoswitchable inhibitor cew65
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
369
structure length
369
Chain Sequence
HAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAAYLHAMDQVVLPALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADICDGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEEIVPLLADIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bordetella
molecule keywords HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE
total genus 136
structure length 369
sequence length 369
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2016-05-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00850 Hist_deacetyl Histone deacetylase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.20 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Histone deacetylase domain 5g3wA00
1ZZ3A 3MZ7A 3ZNSA 4QA5A 4BZ6A 5THTA 3EZPA 5EENA 5LI3A 5D1CA 4BZ8A 5DC7A 3Q9BA 1ZZ1A 4CBYA 5DC8A 4QA4A 3F06A 4A69A 5D1DA 3C10A 5DC6A 5FUEA 5FCWA 4LXZA 4CQFA 1ZZ0A 2VQJA 1T64A 3MENA 3MZ4A 2VQMA 1T67A 4ZURA 5G0JA 5EEFA 5ICNB 3MZ6A 4ZUPA 4ZUOA 5IWGA 5G11A 5THVA 2VQOA 5IX0A 4BZ9A 3Q9CA 3Q9FA 4QA2A 3SFFA 3MAXA 5EFBD 4RN0A 5G1AA 4QA3A 5EFNA 5D1BA 5G0YA 2V5WA 3Q9EA 4CBTA 3F0RA 4RN1A 5A2SA 5G13A 1VKGA 4LY1A 5G0XA 2VQWG 5BWZA 5G1CA 5G10A 3RQDA 1W22A 3MZ3A 5G17A 5EFKB 5THSA 5EFHA 5EEMA 4BZ7A 4RN2A 5G3WA 1C3SA 3C0ZA 5EFGA 3EWFA 3EZTA 4ZUMA 5G0HA 5EEKA 5G1BA 2V5XA 5G0IA 3ZNRA 4QA7A 2VQQA 5EFJD 4QA0A 3EW8A 1T69A 4QA6A 4BZ5A 2VCGA 5G12A 5EEIA 1C3RA 4BKXB 5THUA 2GH6A 3F07A 5JI5A 2VQVA 4QA1A 4ZUNA 5DC5A 3SFHA 3C0YA 5G0GA 5EF8A 1C3PA 4ZUQA 5EF7A
chains in the Genus database with same CATH superfamily
1ZZ3A 3MZ7A 3ZNSA 4QA5A 4BZ6A 5THTA 1PQ3A 1RLAA 3DJ8A 4Q3UA 1HQHA 4RHIA 1TBLA 2PLLA 3EZPA 5EENA 5LI3A 2A0MA 5D1CA 1TBJA 3E9BA 4Q3QA 3NIOA 4BZ8A 5DC7A 5HJ9A 3Q9BA 1ZZ1A 3TF3A 4CBYA 5DC8A 4HXQA 1CEVA 4QA4A 4G3HA 4GSVA 3RLAA 4MYKA 1HQXA 1XFKA 3F06A 4FCIA 4A69A 4Q3RA 5D1DA 3C10A 1WOHA 3GMZA 5DC6A 5FUEA 1WVBA 4LXZA 5FCWA 4CQFA 1ZZ0A 2VQJA 1T64A 3MENA 1T4RA 3THHA 3MZ4A 2VQMA 1P8NA 4IE3A 1T67A 4ZURA 5G0JA 4GWDA 3MFVA 5EEFA 5ICNB 3MZ6A 4ZUPA 4IXUA 2ZAVA 1P8RA 3LHLA 4ZUOA 4RLAA 5IWGA 5G11A 1ZPGA 5THVA 4HWWA 4Q3RC 3PZLA 4GWCA 1P8SA 4Q41A 1TBHA 2VQOA 4RHMA 3E8ZA 5IX0A 3TH7A 4BZ9A 3KV2A 1P8QA 3Q9CA 3Q9FA 4Q3VA 4GSMA 1WVAA 1HQGA 3M1RA 4QA2A 3SFFA 3SJTA 3MAXA 5EFBD 2CEVA 3MJLA 4RN0A 5G1AA 4CEVA 2RLAA 4HZEA 4MXRA 4FCKA 1HQ5A 4Q40A 4QA3A 5D1BA 5EFNA 5G0YA 3THJA 2V5WA 3Q9EA 4CBTA 3F0RA 5CEVA 4RN1A 1T4SA 2AEBA 3NIPA 2PHAA 4MYLA 5A2SA 3SKKA 3E6KA 4Q3SA 5G13A 1VKGA 3MFWA 4MYNA 1TA1A 4LY1A 5G0XA 3CEVA 2VQWG 5BWZA 3MMRA 5G1CA 4MYFA 5G10A 3RQDA 1WOIA 1W22A 4IU0A 5HJAA 3MZ3A 5G17A 5EFKB 5THSA 5EFHA 5EEMA 4BZ7A 1WOGA 1P8MA 4RN2A 5G3WA 1C3SA 3C0ZA 5EFGA 3EWFA 3EZTA 1R1OA 4ZUMA 5G0HA 5EEKA 5G1BA 2V5XA 5G0IA 3ZNRA 4QA7A 2VQQA 5EFJD 1T5FA 4IXVA 4RHLA 4Q42A 5EF7A 3SL0A 4QA0A 2EIVA 3EW8A 4RHKA 1T4PA 1T69A 4QA6A 4BZ5A 1GQ6A 2VCGA 4I06A 2EF5A 4RHQA 5G12A 5EEIA 4IU4A 1C3RA 4GSZA 3NIQA 5RLAA 5THUA 4BKXB 3LP4A 4Q3TA 2PHOA 4Q3PA 4IE2A 4IU5A 2GH6A 3F07A 4ITYA 1T5GA 3THEA 4DZ4A 2VQVA 5JI5A 4QA1A 4ZUNA 5DC5A 1P8OA 3SFHA 3C0YA 5G0GA 5EF8A 3GN0A 1C3PA 3LP7A 3E8QA 3F80A 3E6VA 4ZUQA 1HQFA 4RHJA 3SL1A 4IE1A 1D3VA 2EF4A 1T4TA 1P8PA 4IU1A 1ZPEA 1GQ7A
chains in the Genus database with same CATH topology
1ZZ3A 3MZ7A 3ZNSA 4QA5A 4BZ6A 5THTA 3EZPA 5EENA 5LI3A 5D1CA 4BZ8A 5DC7A 3Q9BA 1ZZ1A 4CBYA 5DC8A 4QA4A 3F06A 4A69A 5D1DA 3C10A 5DC6A 5FUEA 5FCWA 4LXZA 4CQFA 1ZZ0A 2VQJA 1T64A 3MENA 3MZ4A 2VQMA 1T67A 4ZURA 5G0JA 5EEFA 5ICNB 3MZ6A 4ZUPA 4ZUOA 5IWGA 5G11A 5THVA 2VQOA 5IX0A 4BZ9A 3Q9CA 3Q9FA 4QA2A 3SFFA 3MAXA 5EFBD 4RN0A 5G1AA 4QA3A 5EFNA 5D1BA 5G0YA 2V5WA 3Q9EA 4CBTA 3F0RA 4RN1A 5A2SA 5G13A 1VKGA 4LY1A 5G0XA 2VQWG 5BWZA 5G1CA 5G10A 3RQDA 1W22A 3MZ3A 5G17A 5EFKB 5THSA 5EFHA 5EEMA 4BZ7A 4RN2A 5G3WA 1C3SA 3C0ZA 5EFGA 3EWFA 3EZTA 4ZUMA 5G0HA 5EEKA 5G1BA 2V5XA 5G0IA 3ZNRA 4QA7A 2VQQA 5EFJD 4QA0A 3EW8A 1T69A 4QA6A 4BZ5A 2VCGA 5G12A 5EEIA 1C3RA 4BKXB 5THUA 2GH6A 3F07A 5JI5A 2VQVA 4QA1A 4ZUNA 5DC5A 3SFHA 3C0YA 5G0GA 5EF8A 1C3PA 4ZUQA 5EF7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZZ3 A;  3MZ7 A;  3ZNS A;  4QA5 A;  4BZ6 A;  5THT A;  3EZP A;  5EEN A;  5LI3 A;  5D1C A;  4BZ8 A;  5DC7 A;  3Q9B A;  1ZZ1 A;  4CBY A;  5DC8 A;  4QA4 A;  3F06 A;  4A69 A;  5D1D A;  3C10 A;  5DC6 A;  5FUE A;  5FCW A;  4LXZ A;  4CQF A;  1ZZ0 A;  2VQJ A;  1T64 A;  3MEN A;  3MZ4 A;  2VQM A;  1T67 A;  4ZUR A;  5G0J A;  5EEF A;  5ICN B;  3MZ6 A;  4ZUP A;  4ZUO A;  5IWG A;  5G11 A;  5THV A;  2VQO A;  5IX0 A;  4BZ9 A;  3Q9C A;  3Q9F A;  4QA2 A;  3SFF A;  3MAX A;  5EFB D;  4RN0 A;  5G1A A;  4QA3 A;  5EFN A;  5D1B A;  5G0Y A;  2V5W A;  3Q9E A;  4CBT A;  3F0R A;  4RN1 A;  5A2S A;  5G13 A;  1VKG A;  4LY1 A;  5G0X A;  2VQW G;  5BWZ A;  5G1C A;  5G10 A;  3RQD A;  1W22 A;  3MZ3 A;  5G17 A;  5EFK B;  5THS A;  5EFH A;  5EEM A;  4BZ7 A;  4RN2 A;  5G3W A;  1C3S A;  3C0Z A;  5EFG A;  3EWF A;  3EZT A;  4ZUM A;  5G0H A;  5EEK A;  5G1B A;  2V5X A;  5G0I A;  3ZNR A;  4QA7 A;  2VQQ A;  5EFJ D;  4QA0 A;  3EW8 A;  1T69 A;  4QA6 A;  4BZ5 A;  2VCG A;  5G12 A;  5EEI A;  1C3R A;  4BKX B;  5THU A;  2GH6 A;  3F07 A;  5JI5 A;  2VQV A;  4QA1 A;  4ZUN A;  5DC5 A;  3SFH A;  3C0Y A;  5G0G A;  5EF8 A;  1C3P A;  4ZUQ A;  5EF7 A; 
#chains in the Genus database with same CATH topology
 1ZZ3 A;  3MZ7 A;  3ZNS A;  4QA5 A;  4BZ6 A;  5THT A;  1PQ3 A;  1RLA A;  3DJ8 A;  4Q3U A;  1HQH A;  4RHI A;  1TBL A;  2PLL A;  3EZP A;  5EEN A;  5LI3 A;  2A0M A;  5D1C A;  1TBJ A;  3E9B A;  4Q3Q A;  3NIO A;  4BZ8 A;  5DC7 A;  5HJ9 A;  3Q9B A;  1ZZ1 A;  3TF3 A;  4CBY A;  5DC8 A;  4HXQ A;  1CEV A;  4QA4 A;  4G3H A;  4GSV A;  3RLA A;  4MYK A;  1HQX A;  1XFK A;  3F06 A;  4FCI A;  4A69 A;  4Q3R A;  5D1D A;  3C10 A;  1WOH A;  3GMZ A;  5DC6 A;  5FUE A;  1WVB A;  4LXZ A;  5FCW A;  4CQF A;  1ZZ0 A;  2VQJ A;  1T64 A;  3MEN A;  1T4R A;  3THH A;  3MZ4 A;  2VQM A;  1P8N A;  4IE3 A;  1T67 A;  4ZUR A;  5G0J A;  4GWD A;  3MFV A;  5EEF A;  5ICN B;  3MZ6 A;  4ZUP A;  4IXU A;  2ZAV A;  1P8R A;  3LHL A;  4ZUO A;  4RLA A;  5IWG A;  5G11 A;  1ZPG A;  5THV A;  4HWW A;  4Q3R C;  3PZL A;  4GWC A;  1P8S A;  4Q41 A;  1TBH A;  2VQO A;  4RHM A;  3E8Z A;  5IX0 A;  3TH7 A;  4BZ9 A;  3KV2 A;  1P8Q A;  3Q9C A;  3Q9F A;  4Q3V A;  4GSM A;  1WVA A;  1HQG A;  3M1R A;  4QA2 A;  3SFF A;  3SJT A;  3MAX A;  5EFB D;  2CEV A;  3MJL A;  4RN0 A;  5G1A A;  4CEV A;  2RLA A;  4HZE A;  4MXR A;  4FCK A;  1HQ5 A;  4Q40 A;  4QA3 A;  5D1B A;  5EFN A;  5G0Y A;  3THJ A;  2V5W A;  3Q9E A;  4CBT A;  3F0R A;  5CEV A;  4RN1 A;  1T4S A;  2AEB A;  3NIP A;  2PHA A;  4MYL A;  5A2S A;  3SKK A;  3E6K A;  4Q3S A;  5G13 A;  1VKG A;  3MFW A;  4MYN A;  1TA1 A;  4LY1 A;  5G0X A;  3CEV A;  2VQW G;  5BWZ A;  3MMR A;  5G1C A;  4MYF A;  5G10 A;  3RQD A;  1WOI A;  1W22 A;  4IU0 A;  5HJA A;  3MZ3 A;  5G17 A;  5EFK B;  5THS A;  5EFH A;  5EEM A;  4BZ7 A;  1WOG A;  1P8M A;  4RN2 A;  5G3W A;  1C3S A;  3C0Z A;  5EFG A;  3EWF A;  3EZT A;  1R1O A;  4ZUM A;  5G0H A;  5EEK A;  5G1B A;  2V5X A;  5G0I A;  3ZNR A;  4QA7 A;  2VQQ A;  5EFJ D;  1T5F A;  4IXV A;  4RHL A;  4Q42 A;  5EF7 A;  3SL0 A;  4QA0 A;  2EIV A;  3EW8 A;  4RHK A;  1T4P A;  1T69 A;  4QA6 A;  4BZ5 A;  1GQ6 A;  2VCG A;  4I06 A;  2EF5 A;  4RHQ A;  5G12 A;  5EEI A;  4IU4 A;  1C3R A;  4GSZ A;  3NIQ A;  5RLA A;  5THU A;  4BKX B;  3LP4 A;  4Q3T A;  2PHO A;  4Q3P A;  4IE2 A;  4IU5 A;  2GH6 A;  3F07 A;  4ITY A;  1T5G A;  3THE A;  4DZ4 A;  2VQV A;  5JI5 A;  4QA1 A;  4ZUN A;  5DC5 A;  1P8O A;  3SFH A;  3C0Y A;  5G0G A;  5EF8 A;  3GN0 A;  1C3P A;  3LP7 A;  3E8Q A;  3F80 A;  3E6V A;  4ZUQ A;  1HQF A;  4RHJ A;  3SL1 A;  4IE1 A;  1D3V A;  2EF4 A;  1T4T A;  1P8P A;  4IU1 A;  1ZPE A;  1GQ7 A; 
#chains in the Genus database with same CATH homology
 1ZZ3 A;  3MZ7 A;  3ZNS A;  4QA5 A;  4BZ6 A;  5THT A;  3EZP A;  5EEN A;  5LI3 A;  5D1C A;  4BZ8 A;  5DC7 A;  3Q9B A;  1ZZ1 A;  4CBY A;  5DC8 A;  4QA4 A;  3F06 A;  4A69 A;  5D1D A;  3C10 A;  5DC6 A;  5FUE A;  5FCW A;  4LXZ A;  4CQF A;  1ZZ0 A;  2VQJ A;  1T64 A;  3MEN A;  3MZ4 A;  2VQM A;  1T67 A;  4ZUR A;  5G0J A;  5EEF A;  5ICN B;  3MZ6 A;  4ZUP A;  4ZUO A;  5IWG A;  5G11 A;  5THV A;  2VQO A;  5IX0 A;  4BZ9 A;  3Q9C A;  3Q9F A;  4QA2 A;  3SFF A;  3MAX A;  5EFB D;  4RN0 A;  5G1A A;  4QA3 A;  5EFN A;  5D1B A;  5G0Y A;  2V5W A;  3Q9E A;  4CBT A;  3F0R A;  4RN1 A;  5A2S A;  5G13 A;  1VKG A;  4LY1 A;  5G0X A;  2VQW G;  5BWZ A;  5G1C A;  5G10 A;  3RQD A;  1W22 A;  3MZ3 A;  5G17 A;  5EFK B;  5THS A;  5EFH A;  5EEM A;  4BZ7 A;  4RN2 A;  5G3W A;  1C3S A;  3C0Z A;  5EFG A;  3EWF A;  3EZT A;  4ZUM A;  5G0H A;  5EEK A;  5G1B A;  2V5X A;  5G0I A;  3ZNR A;  4QA7 A;  2VQQ A;  5EFJ D;  4QA0 A;  3EW8 A;  1T69 A;  4QA6 A;  4BZ5 A;  2VCG A;  5G12 A;  5EEI A;  1C3R A;  4BKX B;  5THU A;  2GH6 A;  3F07 A;  5JI5 A;  2VQV A;  4QA1 A;  4ZUN A;  5DC5 A;  3SFH A;  3C0Y A;  5G0G A;  5EF8 A;  1C3P A;  4ZUQ A;  5EF7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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