5CEVA

Arginase from bacillus caldevelox, l-lysine complex
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
298
structure length
298
Chain Sequence
KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus caldovelox
molecule keywords PROTEIN (ARGINASE)
total genus 118
structure length 298
sequence length 298
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 5cevA00
4Q3RA 3E6KA 4Q3SA 3THEA 3E8QA 4DZ4A 4IXVA 4HZEA 2PHOA 3NIPA 2EF5A 1R1OA 3GN0A 3MMRA 3KV2A 4IE1A 2AEBA 4HWWA 3MJLA 3LP4A 1TBLA 3E9BA 3SJTA 3F80A 1WOHA 4CEVA 4RHIA 3PZLA 5HJ9A 5CEVA 4IXUA 2RLAA 3M1RA 4RHJA 1GQ6A 1T4PA 3MFWA 4RHMA 4FCIA 3TF3A 3THHA 3SL0A 4ITYA 4RHLA 1PQ3A 4HXQA 1GQ7A 2A0MA 3MFVA 4MXRA 1WOGA 1T4SA 4RHKA 3RLAA 1P8SA 1T5GA 4GWDA 1RLAA 3SKKA 2EIVA 1T4RA 3DJ8A 4Q3TA 4IU0A 4MYFA 4Q3RC 3LHLA 4MYLA 4Q3VA 1HQGA 4Q42A 1TBJA 4FCKA 1ZPGA 1HQFA 1TA1A 4IE2A 1P8QA 4G3HA 4GWCA 3CEVA 3GMZA 1HQ5A 4IE3A 1WVAA 2PLLA 4RHQA 1D3VA 1WVBA 4GSZA 4I06A 1ZPEA 1P8NA 4IU1A 4MYNA 4Q3PA 3SL1A 1CEVA 1TBHA 4MYKA 2PHAA 3NIQA 3E8ZA 1HQHA 1XFKA 5HJAA 1WOIA 1T4TA 4RLAA 3LP7A 1P8MA 4IU4A 3THJA 4GSVA 2ZAVA 1HQXA 4Q41A 1P8PA 3NIOA 4GSMA 2CEVA 4IU5A 4Q3QA 5RLAA 1P8RA 3TH7A 1P8OA 3E6VA 4Q40A 4Q3UA 1T5FA 2EF4A
chains in the Genus database with same CATH superfamily
4BZ7A 4Q3RA 3ZNRA 5EFJD 3E6KA 5G13A 4Q3SA 4ZUOA 5EEFA 2VQVA 3THEA 3E8QA 5IWGA 4DZ4A 4QA0A 5G1BA 5EFBD 5THSA 4IXVA 5A2SA 4HZEA 2PHOA 3NIPA 2EF5A 1R1OA 3GN0A 3MMRA 3KV2A 4IE1A 2AEBA 5G0HA 3SFHA 4BZ5A 3Q9EA 4HWWA 3MJLA 3LP4A 2VQOA 1TBLA 3E9BA 3SJTA 4ZUNA 4QA3A 3C0ZA 3F80A 1C3PA 1WOHA 5THTA 4CEVA 4QA7A 4RHIA 3PZLA 5HJ9A 5CEVA 1ZZ1A 4IXUA 4ZUQA 2RLAA 3M1RA 4RHJA 1GQ6A 1T4PA 3MFWA 4RHMA 5EEMA 5G0YA 3C10A 3MZ3A 5ICNB 3F06A 4FCIA 5LI3A 1T64A 2VQQA 4ITYA 1C3RA 3SL0A 3THHA 4RHLA 4ZUMA 3TF3A 5BWZA 5G0IA 1PQ3A 4HXQA 5G17A 5G10A 5EFGA 1GQ7A 2A0MA 5EFHA 3MFVA 3MZ6A 5G0GA 1ZZ0A 4MXRA 5FCWA 1WOGA 4RN0A 1T4SA 3F07A 4RHKA 3RLAA 1P8SA 1T5GA 4GWDA 4LXZA 1RLAA 3SKKA 2EIVA 3EWFA 1T4RA 3EZTA 3RQDA 3SFFA 3DJ8A 4Q3TA 4IU0A 4MYFA 5G1CA 1T69A 4Q3RC 3LHLA 4MYLA 4Q3VA 1HQGA 4Q42A 3MAXA 1TBJA 5G11A 4QA2A 4FCKA 4BZ8A 5G0JA 3Q9FA 1ZPGA 2VQWG 5EF7A 1HQFA 1TA1A 5THVA 4IE2A 1P8QA 5DC5A 4G3HA 2V5XA 4GWCA 3CEVA 3GMZA 3ZNSA 1HQ5A 4BKXB 4IE3A 1WVAA 5G1AA 4A69A 5DC7A 2PLLA 4RHQA 1D3VA 1WVBA 4GSZA 4BZ6A 3EW8A 5G3WA 1W22A 4I06A 1ZPEA 1P8NA 4IU1A 4MYNA 4QA6A 4QA1A 4Q3PA 5D1DA 5EEIA 3SL1A 3Q9BA 2VQJA 1ZZ3A 1CEVA 1TBHA 4MYKA 2PHAA 4QA4A 5EEKA 3NIQA 5D1BA 3E8ZA 4QA5A 5FUEA 5EFKB 3F0RA 2VQMA 1HQHA 1XFKA 4ZUPA 5HJAA 1WOIA 1T4TA 4RN1A 4CBTA 3Q9CA 1VKGA 5DC8A 4RLAA 3LP7A 1P8MA 4IU4A 3THJA 4GSVA 2ZAVA 4CBYA 1HQXA 4Q41A 3C0YA 4LY1A 5EF8A 5G0XA 1T67A 1P8PA 3EZPA 3NIOA 4GSMA 5EENA 2CEVA 3MZ4A 4IU5A 4Q3QA 5RLAA 1P8RA 3TH7A 2VCGA 5THUA 3MZ7A 1P8OA 3E6VA 3MENA 5IX0A 4CQFA 4Q40A 5JI5A 1C3SA 2GH6A 4RN2A 5D1CA 4Q3UA 5DC6A 5G12A 1T5FA 4ZURA 2V5WA 4BZ9A 5EFNA 2EF4A
chains in the Genus database with same CATH topology
4Q3RA 3E6KA 4Q3SA 3THEA 3E8QA 4DZ4A 4IXVA 4HZEA 2PHOA 3NIPA 2EF5A 1R1OA 3GN0A 3MMRA 3KV2A 4IE1A 2AEBA 4HWWA 3MJLA 3LP4A 1TBLA 3E9BA 3SJTA 3F80A 1WOHA 4CEVA 4RHIA 3PZLA 5HJ9A 5CEVA 4IXUA 2RLAA 3M1RA 4RHJA 1GQ6A 1T4PA 3MFWA 4RHMA 4FCIA 3TF3A 3THHA 3SL0A 4ITYA 4RHLA 1PQ3A 4HXQA 1GQ7A 2A0MA 3MFVA 4MXRA 1WOGA 1T4SA 4RHKA 3RLAA 1P8SA 1T5GA 4GWDA 1RLAA 3SKKA 2EIVA 1T4RA 3DJ8A 4Q3TA 4IU0A 4MYFA 4Q3RC 3LHLA 4MYLA 4Q3VA 1HQGA 4Q42A 1TBJA 4FCKA 1ZPGA 1HQFA 1TA1A 4IE2A 1P8QA 4G3HA 4GWCA 3CEVA 3GMZA 1HQ5A 4IE3A 1WVAA 2PLLA 4RHQA 1D3VA 1WVBA 4GSZA 4I06A 1ZPEA 1P8NA 4IU1A 4MYNA 4Q3PA 3SL1A 1CEVA 1TBHA 4MYKA 2PHAA 3NIQA 3E8ZA 1HQHA 1XFKA 5HJAA 1WOIA 1T4TA 4RLAA 3LP7A 1P8MA 4IU4A 3THJA 4GSVA 2ZAVA 1HQXA 4Q41A 1P8PA 3NIOA 4GSMA 2CEVA 4IU5A 4Q3QA 5RLAA 1P8RA 3TH7A 1P8OA 3E6VA 4Q40A 4Q3UA 1T5FA 2EF4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q3R A;  3E6K A;  4Q3S A;  3THE A;  3E8Q A;  4DZ4 A;  4IXV A;  4HZE A;  2PHO A;  3NIP A;  2EF5 A;  1R1O A;  3GN0 A;  3MMR A;  3KV2 A;  4IE1 A;  2AEB A;  4HWW A;  3MJL A;  3LP4 A;  1TBL A;  3E9B A;  3SJT A;  3F80 A;  1WOH A;  4CEV A;  4RHI A;  3PZL A;  5HJ9 A;  5CEV A;  4IXU A;  2RLA A;  3M1R A;  4RHJ A;  1GQ6 A;  1T4P A;  3MFW A;  4RHM A;  4FCI A;  3TF3 A;  3THH A;  3SL0 A;  4ITY A;  4RHL A;  1PQ3 A;  4HXQ A;  1GQ7 A;  2A0M A;  3MFV A;  4MXR A;  1WOG A;  1T4S A;  4RHK A;  3RLA A;  1P8S A;  1T5G A;  4GWD A;  1RLA A;  3SKK A;  2EIV A;  1T4R A;  3DJ8 A;  4Q3T A;  4IU0 A;  4MYF A;  4Q3R C;  3LHL A;  4MYL A;  4Q3V A;  1HQG A;  4Q42 A;  1TBJ A;  4FCK A;  1ZPG A;  1HQF A;  1TA1 A;  4IE2 A;  1P8Q A;  4G3H A;  4GWC A;  3CEV A;  3GMZ A;  1HQ5 A;  4IE3 A;  1WVA A;  2PLL A;  4RHQ A;  1D3V A;  1WVB A;  4GSZ A;  4I06 A;  1ZPE A;  1P8N A;  4IU1 A;  4MYN A;  4Q3P A;  3SL1 A;  1CEV A;  1TBH A;  4MYK A;  2PHA A;  3NIQ A;  3E8Z A;  1HQH A;  1XFK A;  5HJA A;  1WOI A;  1T4T A;  4RLA A;  3LP7 A;  1P8M A;  4IU4 A;  3THJ A;  4GSV A;  2ZAV A;  1HQX A;  4Q41 A;  1P8P A;  3NIO A;  4GSM A;  2CEV A;  4IU5 A;  4Q3Q A;  5RLA A;  1P8R A;  3TH7 A;  1P8O A;  3E6V A;  4Q40 A;  4Q3U A;  1T5F A;  2EF4 A; 
#chains in the Genus database with same CATH topology
 4BZ7 A;  4Q3R A;  3ZNR A;  5EFJ D;  3E6K A;  5G13 A;  4Q3S A;  4ZUO A;  5EEF A;  2VQV A;  3THE A;  3E8Q A;  5IWG A;  4DZ4 A;  4QA0 A;  5G1B A;  5EFB D;  5THS A;  4IXV A;  5A2S A;  4HZE A;  2PHO A;  3NIP A;  2EF5 A;  1R1O A;  3GN0 A;  3MMR A;  3KV2 A;  4IE1 A;  2AEB A;  5G0H A;  3SFH A;  4BZ5 A;  3Q9E A;  4HWW A;  3MJL A;  3LP4 A;  2VQO A;  1TBL A;  3E9B A;  3SJT A;  4ZUN A;  4QA3 A;  3C0Z A;  3F80 A;  1C3P A;  1WOH A;  5THT A;  4CEV A;  4QA7 A;  4RHI A;  3PZL A;  5HJ9 A;  5CEV A;  1ZZ1 A;  4IXU A;  4ZUQ A;  2RLA A;  3M1R A;  4RHJ A;  1GQ6 A;  1T4P A;  3MFW A;  4RHM A;  5EEM A;  5G0Y A;  3C10 A;  3MZ3 A;  5ICN B;  3F06 A;  4FCI A;  5LI3 A;  1T64 A;  2VQQ A;  4ITY A;  1C3R A;  3SL0 A;  3THH A;  4RHL A;  4ZUM A;  3TF3 A;  5BWZ A;  5G0I A;  1PQ3 A;  4HXQ A;  5G17 A;  5G10 A;  5EFG A;  1GQ7 A;  2A0M A;  5EFH A;  3MFV A;  3MZ6 A;  5G0G A;  1ZZ0 A;  4MXR A;  5FCW A;  1WOG A;  4RN0 A;  1T4S A;  3F07 A;  4RHK A;  3RLA A;  1P8S A;  1T5G A;  4GWD A;  4LXZ A;  1RLA A;  3SKK A;  2EIV A;  3EWF A;  1T4R A;  3EZT A;  3RQD A;  3SFF A;  3DJ8 A;  4Q3T A;  4IU0 A;  4MYF A;  5G1C A;  1T69 A;  4Q3R C;  3LHL A;  4MYL A;  4Q3V A;  1HQG A;  4Q42 A;  3MAX A;  1TBJ A;  5G11 A;  4QA2 A;  4FCK A;  4BZ8 A;  5G0J A;  3Q9F A;  1ZPG A;  2VQW G;  5EF7 A;  1HQF A;  1TA1 A;  5THV A;  4IE2 A;  1P8Q A;  5DC5 A;  4G3H A;  2V5X A;  4GWC A;  3CEV A;  3GMZ A;  3ZNS A;  1HQ5 A;  4BKX B;  4IE3 A;  1WVA A;  5G1A A;  4A69 A;  5DC7 A;  2PLL A;  4RHQ A;  1D3V A;  1WVB A;  4GSZ A;  4BZ6 A;  3EW8 A;  5G3W A;  1W22 A;  4I06 A;  1ZPE A;  1P8N A;  4IU1 A;  4MYN A;  4QA6 A;  4QA1 A;  4Q3P A;  5D1D A;  5EEI A;  3SL1 A;  3Q9B A;  2VQJ A;  1ZZ3 A;  1CEV A;  1TBH A;  4MYK A;  2PHA A;  4QA4 A;  5EEK A;  3NIQ A;  5D1B A;  3E8Z A;  4QA5 A;  5FUE A;  5EFK B;  3F0R A;  2VQM A;  1HQH A;  1XFK A;  4ZUP A;  5HJA A;  1WOI A;  1T4T A;  4RN1 A;  4CBT A;  3Q9C A;  1VKG A;  5DC8 A;  4RLA A;  3LP7 A;  1P8M A;  4IU4 A;  3THJ A;  4GSV A;  2ZAV A;  4CBY A;  1HQX A;  4Q41 A;  3C0Y A;  4LY1 A;  5EF8 A;  5G0X A;  1T67 A;  1P8P A;  3EZP A;  3NIO A;  4GSM A;  5EEN A;  2CEV A;  3MZ4 A;  4IU5 A;  4Q3Q A;  5RLA A;  1P8R A;  3TH7 A;  2VCG A;  5THU A;  3MZ7 A;  1P8O A;  3E6V A;  3MEN A;  5IX0 A;  4CQF A;  4Q40 A;  5JI5 A;  1C3S A;  2GH6 A;  4RN2 A;  5D1C A;  4Q3U A;  5DC6 A;  5G12 A;  1T5F A;  4ZUR A;  2V5W A;  4BZ9 A;  5EFN A;  2EF4 A; 
#chains in the Genus database with same CATH homology
 4Q3R A;  3E6K A;  4Q3S A;  3THE A;  3E8Q A;  4DZ4 A;  4IXV A;  4HZE A;  2PHO A;  3NIP A;  2EF5 A;  1R1O A;  3GN0 A;  3MMR A;  3KV2 A;  4IE1 A;  2AEB A;  4HWW A;  3MJL A;  3LP4 A;  1TBL A;  3E9B A;  3SJT A;  3F80 A;  1WOH A;  4CEV A;  4RHI A;  3PZL A;  5HJ9 A;  5CEV A;  4IXU A;  2RLA A;  3M1R A;  4RHJ A;  1GQ6 A;  1T4P A;  3MFW A;  4RHM A;  4FCI A;  3TF3 A;  3THH A;  3SL0 A;  4ITY A;  4RHL A;  1PQ3 A;  4HXQ A;  1GQ7 A;  2A0M A;  3MFV A;  4MXR A;  1WOG A;  1T4S A;  4RHK A;  3RLA A;  1P8S A;  1T5G A;  4GWD A;  1RLA A;  3SKK A;  2EIV A;  1T4R A;  3DJ8 A;  4Q3T A;  4IU0 A;  4MYF A;  4Q3R C;  3LHL A;  4MYL A;  4Q3V A;  1HQG A;  4Q42 A;  1TBJ A;  4FCK A;  1ZPG A;  1HQF A;  1TA1 A;  4IE2 A;  1P8Q A;  4G3H A;  4GWC A;  3CEV A;  3GMZ A;  1HQ5 A;  4IE3 A;  1WVA A;  2PLL A;  4RHQ A;  1D3V A;  1WVB A;  4GSZ A;  4I06 A;  1ZPE A;  1P8N A;  4IU1 A;  4MYN A;  4Q3P A;  3SL1 A;  1CEV A;  1TBH A;  4MYK A;  2PHA A;  3NIQ A;  3E8Z A;  1HQH A;  1XFK A;  5HJA A;  1WOI A;  1T4T A;  4RLA A;  3LP7 A;  1P8M A;  4IU4 A;  3THJ A;  4GSV A;  2ZAV A;  1HQX A;  4Q41 A;  1P8P A;  3NIO A;  4GSM A;  2CEV A;  4IU5 A;  4Q3Q A;  5RLA A;  1P8R A;  3TH7 A;  1P8O A;  3E6V A;  4Q40 A;  4Q3U A;  1T5F A;  2EF4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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