5G0I | Genus

Total Genus 294

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	294
sequence length	744
structure length	722
Chain Sequence	SKATGTGLVYVDAFTRFHCLWDASHPECPARVSTVMEMLETEGLLGRCVQVEARAVTEDELLLVHTKEYVELMKSTQNMTEEELKTLAEKYDSVYLHPGFFSSACLSVGSVLQLVDKVMTSQLRNGFSINRPPGHHAQADKMNGFCMFNNLAIAARYAQKRHRVQRVLIVDWDVHHGQGIQYIFEEDPSVLYFSVHRYEDGSFWPHLKESDSSSVGSGAGQGYNINLPWNKVGMESGDYITAFQQLLLPVAYEFQPQLVLVAAGFDAVIGDPKGGMQVSPECFSILTHMLKGVAQGRLVLALEGGYNLQSTAEGVCASMRSLLGDPCPHLPSSGAPCESALKSISKTISDLYPFWKSLQTFEPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLRVNI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5d012d689d0c17ba90244e1e/pdb.gz

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Cell cycle
source organism	Danio rerio
publication title	Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition pubmed doi rcsb
molecule keywords	HDAC6
total genus	294
structure length	722
sequence length	744
chains with identical sequence	B
ec nomenclature
pdb deposition date	2016-03-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00850	Hist_deacetyl	Histone deacetylase domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.800.20	Alpha Beta	3-Layer(aba) Sandwich	Arginase; Chain A	Histone deacetylase domain	5g0iA02
3.40.800.20	Alpha Beta	3-Layer(aba) Sandwich	Arginase; Chain A	Histone deacetylase domain	5g0iA01

3C0ZA 4ZUOA 3F07A 5EENA 5IWGA 5EEIA 5G11A 5EF8A 3MZ7A 5G0XA 3EZTA 2VQJA 2VQWG 5EFNA 2VCGA 4BZ7A 5THVA 5DC7A 5G13A 5BWZA 1C3SA 4A69A 5G0GA 2VQOA 2GH6A 5EFHA 5EFBD 3MZ6A 4RN2A 4QA1A 3Q9CA 5THUA 4LY1A 1W22A 5G3WA 3ZNRA 3C0YA 1C3RA 5EF7A 3C10A 5THTA 4CQFA 4LXZA 4RN0A 5ICNB 5LI3A 5G10A 1T69A 5D1CA 5FCWA 5DC5A 1ZZ0A 5EEMA 5EEKA 4QA4A 5G17A 4CBYA 3MAXA 1C3PA 4QA2A 4QA7A 1VKGA 2V5WA 3MZ3A 2VQVA 4ZUQA 5EFGA 1ZZ1A 4BZ6A 5EFJD 4ZURA 3SFFA 5G0JA 3SFHA 5EFKB 5A2SA 4BZ8A 3Q9EA 3MENA 3Q9BA 2VQQA 4RN1A 5FUEA 5D1DA 5G12A 2V5XA 5DC6A 5JI5A 3F0RA 5G0IA 3EW8A 3MZ4A 1T67A 4ZUNA 4CBTA 3EWFA 4QA5A 3EZPA 4QA3A 1ZZ3A 5G0YA 5D1BA 1T64A 5G1BA 5G1CA 2VQMA 5G1AA 3F06A 3Q9FA 3ZNSA 5EEFA 5THSA 5IX0A 4QA6A 4QA0A 4ZUMA 4BZ9A 4ZUPA 5DC8A 4BKXB 4BZ5A 5G0HA 3RQDA
chains in the Genus database with same CATH superfamily

4IE1A 3C0ZA 4ZUOA 3MFVA 2EF4A 1T4TA 1WOHA 3F07A 4RHIA 4Q3VA 5EENA 5EEIA 5IWGA 3SL0A 5G11A 4Q41A 3M1RA 3MZ7A 5EF8A 4IXUA 3E6KA 4Q3UA 5G0XA 3F80A 1WVBA 2PHAA 3EZTA 2VQJA 4GSVA 2VQWG 1RLAA 4HWWA 1GQ7A 5EFNA 2VCGA 4FCIA 4BZ7A 5THVA 4RLAA 5DC7A 3MJLA 5G13A 4RHJA 3TH7A 5BWZA 1C3SA 1P8PA 4A69A 4RHKA 1P8RA 4MYFA 5G0GA 2VQOA 3SL1A 2GH6A 5EFHA 5EFBD 3MZ6A 3THJA 4RN2A 4QA1A 4HZEA 3Q9CA 1P8OA 1TBHA 5THUA 4LY1A 4DZ4A 1W22A 2A0MA 5G3WA 2PHOA 3ZNRA 3C0YA 1C3RA 5EF7A 3C10A 5HJAA 5THTA 4IU1A 4IXVA 4CQFA 1CEVA 4LXZA 4I06A 4RN0A 2EIVA 5ICNB 1WOGA 5LI3A 5G10A 4Q3SA 1T69A 3KV2A 4Q42A 5D1CA 5DC5A 5FCWA 3TF3A 4Q3RC 1ZZ0A 2EF5A 5EEMA 1T5FA 1GQ6A 5EEKA 5HJ9A 4IE2A 4QA4A 5G17A 4CBYA 4HXQA 4MYKA 4MYLA 3E8ZA 4Q40A 4G3HA 3MAXA 1C3PA 4QA2A 1XFKA 3E6VA 3NIOA 4QA7A 5CEVA 1VKGA 1T4SA 2V5WA 3PZLA 2VQVA 3MZ3A 4ZUQA 5EFGA 3DJ8A 1ZZ1A 4BZ6A 5EFJD 1D3VA 1T4PA 4ZURA 3SFFA 1WVAA 3RLAA 3THEA 5G0JA 3NIQA 3GMZA 4GWDA 5EFKB 3SFHA 5A2SA 3E9BA 4ITYA 4BZ8A 4Q3QA 1T4RA 4Q3TA 3Q9EA 1P8NA 3MENA 1PQ3A 3Q9BA 4RHQA 1HQXA 2VQQA 4RN1A 5FUEA 5D1DA 2RLAA 4Q3PA 5G12A 2V5XA 5DC6A 1HQHA 5JI5A 3F0RA 1TBLA 5G0IA 4GWCA 3EW8A 3MZ4A 4RHMA 1T67A 4ZUNA 4IU0A 3MFWA 4CBTA 3EWFA 1ZPGA 4QA5A 4RHLA 1TA1A 1P8QA 3EZPA 4IE3A 2AEBA 4QA3A 1ZZ3A 1TBJA 2ZAVA 3LP4A 5G0YA 2CEVA 5D1BA 3MMRA 4IU5A 3THHA 1T5GA 3CEVA 1T64A 2PLLA 5G1BA 5G1CA 2VQMA 1P8MA 1WOIA 3E8QA 1HQGA 3F06A 4MYNA 5G1AA 4Q3RA 3Q9FA 4FCKA 4MXRA 3ZNSA 5EEFA 3SKKA 3LP7A 5THSA 5IX0A 3SJTA 4QA6A 1ZPEA 3NIPA 4QA0A 4ZUMA 4ZUPA 5DC8A 4BKXB 4BZ9A 1P8SA 4BZ5A 4CEVA 5RLAA 4IU4A 5G0HA 1R1OA 4GSMA 1HQ5A 1HQFA 3GN0A 3RQDA 3LHLA 4GSZA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3C0Z A;  4ZUO A;  3F07 A;  5EEN A;  5IWG A;  5EEI A;  5G11 A;  5EF8 A;  3MZ7 A;  5G0X A;  3EZT A;  2VQJ A;  2VQW G;  5EFN A;  2VCG A;  4BZ7 A;  5THV A;  5DC7 A;  5G13 A;  5BWZ A;  1C3S A;  4A69 A;  5G0G A;  2VQO A;  2GH6 A;  5EFH A;  5EFB D;  3MZ6 A;  4RN2 A;  4QA1 A;  3Q9C A;  5THU A;  4LY1 A;  1W22 A;  5G3W A;  3ZNR A;  3C0Y A;  1C3R A;  5EF7 A;  3C10 A;  5THT A;  4CQF A;  4LXZ A;  4RN0 A;  5ICN B;  5LI3 A;  5G10 A;  1T69 A;  5D1C A;  5FCW A;  5DC5 A;  1ZZ0 A;  5EEM A;  5EEK A;  4QA4 A;  5G17 A;  4CBY A;  3MAX A;  1C3P A;  4QA2 A;  4QA7 A;  1VKG A;  2V5W A;  3MZ3 A;  2VQV A;  4ZUQ A;  5EFG A;  1ZZ1 A;  4BZ6 A;  5EFJ D;  4ZUR A;  3SFF A;  5G0J A;  3SFH A;  5EFK B;  5A2S A;  4BZ8 A;  3Q9E A;  3MEN A;  3Q9B A;  2VQQ A;  4RN1 A;  5FUE A;  5D1D A;  5G12 A;  2V5X A;  5DC6 A;  5JI5 A;  3F0R A;  5G0I A;  3EW8 A;  3MZ4 A;  1T67 A;  4ZUN A;  4CBT A;  3EWF A;  4QA5 A;  3EZP A;  4QA3 A;  1ZZ3 A;  5G0Y A;  5D1B A;  1T64 A;  5G1B A;  5G1C A;  2VQM A;  5G1A A;  3F06 A;  3Q9F A;  3ZNS A;  5EEF A;  5THS A;  5IX0 A;  4QA6 A;  4QA0 A;  4ZUM A;  4BZ9 A;  4ZUP A;  5DC8 A;  4BKX B;  4BZ5 A;  5G0H A;  3RQD A; 
#chains in the Genus database with same CATH topology
 4IE1 A;  3C0Z A;  4ZUO A;  3MFV A;  2EF4 A;  1T4T A;  1WOH A;  3F07 A;  4RHI A;  4Q3V A;  5EEN A;  5EEI A;  5IWG A;  3SL0 A;  5G11 A;  4Q41 A;  3M1R A;  3MZ7 A;  5EF8 A;  4IXU A;  3E6K A;  4Q3U A;  5G0X A;  3F80 A;  1WVB A;  2PHA A;  3EZT A;  2VQJ A;  4GSV A;  2VQW G;  1RLA A;  4HWW A;  1GQ7 A;  5EFN A;  2VCG A;  4FCI A;  4BZ7 A;  5THV A;  4RLA A;  5DC7 A;  3MJL A;  5G13 A;  4RHJ A;  3TH7 A;  5BWZ A;  1C3S A;  1P8P A;  4A69 A;  4RHK A;  1P8R A;  4MYF A;  5G0G A;  2VQO A;  3SL1 A;  2GH6 A;  5EFH A;  5EFB D;  3MZ6 A;  3THJ A;  4RN2 A;  4QA1 A;  4HZE A;  3Q9C A;  1P8O A;  1TBH A;  5THU A;  4LY1 A;  4DZ4 A;  1W22 A;  2A0M A;  5G3W A;  2PHO A;  3ZNR A;  3C0Y A;  1C3R A;  5EF7 A;  3C10 A;  5HJA A;  5THT A;  4IU1 A;  4IXV A;  4CQF A;  1CEV A;  4LXZ A;  4I06 A;  4RN0 A;  2EIV A;  5ICN B;  1WOG A;  5LI3 A;  5G10 A;  4Q3S A;  1T69 A;  3KV2 A;  4Q42 A;  5D1C A;  5DC5 A;  5FCW A;  3TF3 A;  4Q3R C;  1ZZ0 A;  2EF5 A;  5EEM A;  1T5F A;  1GQ6 A;  5EEK A;  5HJ9 A;  4IE2 A;  4QA4 A;  5G17 A;  4CBY A;  4HXQ A;  4MYK A;  4MYL A;  3E8Z A;  4Q40 A;  4G3H A;  3MAX A;  1C3P A;  4QA2 A;  1XFK A;  3E6V A;  3NIO A;  4QA7 A;  5CEV A;  1VKG A;  1T4S A;  2V5W A;  3PZL A;  2VQV A;  3MZ3 A;  4ZUQ A;  5EFG A;  3DJ8 A;  1ZZ1 A;  4BZ6 A;  5EFJ D;  1D3V A;  1T4P A;  4ZUR A;  3SFF A;  1WVA A;  3RLA A;  3THE A;  5G0J A;  3NIQ A;  3GMZ A;  4GWD A;  5EFK B;  3SFH A;  5A2S A;  3E9B A;  4ITY A;  4BZ8 A;  4Q3Q A;  1T4R A;  4Q3T A;  3Q9E A;  1P8N A;  3MEN A;  1PQ3 A;  3Q9B A;  4RHQ A;  1HQX A;  2VQQ A;  4RN1 A;  5FUE A;  5D1D A;  2RLA A;  4Q3P A;  5G12 A;  2V5X A;  5DC6 A;  1HQH A;  5JI5 A;  3F0R A;  1TBL A;  5G0I A;  4GWC A;  3EW8 A;  3MZ4 A;  4RHM A;  1T67 A;  4ZUN A;  4IU0 A;  3MFW A;  4CBT A;  3EWF A;  1ZPG A;  4QA5 A;  4RHL A;  1TA1 A;  1P8Q A;  3EZP A;  4IE3 A;  2AEB A;  4QA3 A;  1ZZ3 A;  1TBJ A;  2ZAV A;  3LP4 A;  5G0Y A;  2CEV A;  5D1B A;  3MMR A;  4IU5 A;  3THH A;  1T5G A;  3CEV A;  1T64 A;  2PLL A;  5G1B A;  5G1C A;  2VQM A;  1P8M A;  1WOI A;  3E8Q A;  1HQG A;  3F06 A;  4MYN A;  5G1A A;  4Q3R A;  3Q9F A;  4FCK A;  4MXR A;  3ZNS A;  5EEF A;  3SKK A;  3LP7 A;  5THS A;  5IX0 A;  3SJT A;  4QA6 A;  1ZPE A;  3NIP A;  4QA0 A;  4ZUM A;  4ZUP A;  5DC8 A;  4BKX B;  4BZ9 A;  1P8S A;  4BZ5 A;  4CEV A;  5RLA A;  4IU4 A;  5G0H A;  1R1O A;  4GSM A;  1HQ5 A;  1HQF A;  3GN0 A;  3RQD A;  3LHL A;  4GSZ A; 
#chains in the Genus database with same CATH homology
 3C0Z A;  4ZUO A;  3F07 A;  5EEN A;  5IWG A;  5EEI A;  5G11 A;  5EF8 A;  3MZ7 A;  5G0X A;  3EZT A;  2VQJ A;  2VQW G;  5EFN A;  2VCG A;  4BZ7 A;  5THV A;  5DC7 A;  5G13 A;  5BWZ A;  1C3S A;  4A69 A;  5G0G A;  2VQO A;  2GH6 A;  5EFH A;  5EFB D;  3MZ6 A;  4RN2 A;  4QA1 A;  3Q9C A;  5THU A;  4LY1 A;  1W22 A;  5G3W A;  3ZNR A;  3C0Y A;  1C3R A;  5EF7 A;  3C10 A;  5THT A;  4CQF A;  4LXZ A;  4RN0 A;  5ICN B;  5LI3 A;  5G10 A;  1T69 A;  5D1C A;  5FCW A;  5DC5 A;  1ZZ0 A;  5EEM A;  5EEK A;  4QA4 A;  5G17 A;  4CBY A;  3MAX A;  1C3P A;  4QA2 A;  4QA7 A;  1VKG A;  2V5W A;  3MZ3 A;  2VQV A;  4ZUQ A;  5EFG A;  1ZZ1 A;  4BZ6 A;  5EFJ D;  4ZUR A;  3SFF A;  5G0J A;  3SFH A;  5EFK B;  5A2S A;  4BZ8 A;  3Q9E A;  3MEN A;  3Q9B A;  2VQQ A;  4RN1 A;  5FUE A;  5D1D A;  5G12 A;  2V5X A;  5DC6 A;  5JI5 A;  3F0R A;  5G0I A;  3EW8 A;  3MZ4 A;  1T67 A;  4ZUN A;  4CBT A;  3EWF A;  4QA5 A;  3EZP A;  4QA3 A;  1ZZ3 A;  5G0Y A;  5D1B A;  1T64 A;  5G1B A;  5G1C A;  2VQM A;  5G1A A;  3F06 A;  3Q9F A;  3ZNS A;  5EEF A;  5THS A;  5IX0 A;  4QA6 A;  4QA0 A;  4ZUM A;  4BZ9 A;  4ZUP A;  5DC8 A;  4BKX B;  4BZ5 A;  5G0H A;  3RQD A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5G0IA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations