5G1CA

Structure of hdac like protein from bordetella alcaligenes bound the photoswitchable pyrazole inhibitor cew395
Total Genus 142
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
142
sequence length
370
structure length
370
Chain Sequence
HHAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAAYLHAMDQVVLPALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADICDGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEEIVPLLADIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Alcaligenes
molecule keywords HISTONE DEACETYLASE-LIKE AMIDOHYDROLASE
total genus 142
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.5.1.4: Amidase.
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00850 Hist_deacetyl Histone deacetylase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.20 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Histone deacetylase domain 5g1cA00
4LXZA 5THTA 5G0YA 1C3PA 5EFJD 1C3RA 4BZ7A 4ZUNA 4CQFA 1ZZ3A 4QA3A 5FCWA 5DC5A 5EF7A 4RN0A 4QA7A 4BZ6A 5EFBD 2GH6A 1ZZ0A 2V5WA 3C0YA 3MZ3A 2VQVA 5EFHA 4RN2A 3EWFA 5G12A 4A69A 5D1CA 5THSA 5EFGA 3MZ7A 5FUEA 2VQJA 3ZNSA 5ICNB 5G3WA 5G1BA 5G0IA 5IX0A 5G0GA 5DC7A 5EFKB 3C10A 5BWZA 5D1DA 3C0ZA 1C3SA 4CBTA 4QA6A 4QA4A 5JI5A 2VQWG 5EF8A 3SFFA 1VKGA 4BZ5A 5G17A 4ZUPA 5EEIA 2VCGA 4ZUMA 3EZTA 4ZUQA 4QA0A 3F0RA 5G11A 5A2SA 2VQMA 3MZ6A 5THUA 5EEFA 3Q9BA 1T67A 5IWGA 5EEMA 1W22A 3Q9EA 4BZ8A 5DC6A 4QA1A 3F06A 4ZUOA 2VQOA 3EZPA 3ZNRA 4CBYA 1T64A 4ZURA 5LI3A 5THVA 3Q9FA 4BKXB 3F07A 5G10A 3RQDA 1ZZ1A 5DC8A 5EEKA 5G0XA 3MENA 2VQQA 5G13A 5EENA 4RN1A 5G0JA 4QA5A 5D1BA 3Q9CA 3MAXA 2V5XA 4QA2A 3SFHA 4BZ9A 3EW8A 3MZ4A 5G1AA 4LY1A 1T69A 5G1CA 5EFNA 5G0HA
chains in the Genus database with same CATH superfamily
2EF5A 4GWCA 3TF3A 4LXZA 1ZPEA 5THTA 4FCIA 5G0YA 1C3PA 5EFJD 1C3RA 4BZ7A 4ZUNA 4CQFA 1ZZ3A 4QA3A 5FCWA 4IE1A 5DC5A 5HJAA 5EF7A 4RN0A 3LP4A 2PHAA 2A0MA 4QA7A 4BZ6A 5EFBD 1WVBA 1ZZ0A 2GH6A 2V5WA 3THJA 3C0YA 3MZ3A 4Q3VA 2VQVA 5EFHA 4RN2A 3EWFA 1P8MA 5G12A 5D1CA 4A69A 1ZPGA 4IE2A 4HWWA 5THSA 5EFGA 3MZ7A 1HQHA 2VQJA 5FUEA 3SJTA 3ZNSA 4Q3TA 5ICNB 4MYKA 1D3VA 5G3WA 3RLAA 5G1BA 5G0IA 3THEA 5IX0A 4IE3A 5G0GA 1T5GA 5CEVA 1HQ5A 5DC7A 2PLLA 2ZAVA 4ZUOA 4HZEA 5EFKB 1P8NA 3C10A 5BWZA 4RHJA 5D1DA 4Q3UA 3C0ZA 1T4PA 1C3SA 3MJLA 4MYFA 4CBTA 3PZLA 4QA6A 1TBHA 4QA4A 5JI5A 3DJ8A 2CEVA 3MMRA 2EIVA 2VQWG 3GN0A 4GSMA 5EF8A 4Q41A 3SFFA 1VKGA 1P8OA 5G17A 4BZ5A 4ZUPA 5EEIA 2VCGA 4MYLA 4ZUMA 3EZTA 4RHIA 4ZUQA 1P8QA 3MFVA 4QA0A 3CEVA 4RLAA 1T4SA 1P8RA 3F0RA 4GSVA 3NIPA 4Q3SA 4Q40A 5G11A 3THHA 5A2SA 2VQMA 3MFWA 3MZ6A 1CEVA 3E6VA 3LHLA 5THUA 2EF4A 3SKKA 5EEFA 2RLAA 1T67A 3Q9BA 5IWGA 5EEMA 4IXUA 3ZNRA 1W22A 3Q9EA 4RHKA 1HQXA 4BZ8A 1WOIA 4QA1A 1PQ3A 3F06A 3EZPA 2VQOA 1P8PA 1T4TA 5DC6A 3NIQA 1T64A 4G3HA 4ITYA 4I06A 4Q3RA 4ZURA 3SL0A 4CBYA 4Q3QA 3TH7A 5LI3A 5THVA 4GSZA 5HJ9A 3Q9FA 4BKXB 3F07A 3M1RA 5G10A 5RLAA 1GQ7A 3RQDA 3GMZA 4CEVA 1ZZ1A 4IXVA 5DC8A 4RHQA 5EEKA 1GQ6A 4Q42A 3SL1A 3E8QA 4Q3PA 3F80A 5G0XA 3LP7A 3MENA 2PHOA 2VQQA 5G13A 1WOHA 5EENA 4IU5A 4Q3RC 4IU4A 3E6KA 1WVAA 4RN1A 5G0JA 3NIOA 4MXRA 4QA5A 5D1BA 3Q9CA 3MAXA 2V5XA 1XFKA 3KV2A 4QA2A 4RHLA 4HXQA 3SFHA 4RHMA 4BZ9A 3E9BA 1T5FA 3EW8A 3MZ4A 1TBJA 1R1OA 1P8SA 5G1AA 1T4RA 1HQFA 4FCKA 3E8ZA 4MYNA 4GWDA 4DZ4A 4IU1A 1TA1A 4LY1A 1T69A 1RLAA 1HQGA 1TBLA 4IU0A 5G1CA 5EFNA 1WOGA 5G0HA 2AEBA
chains in the Genus database with same CATH topology
4LXZA 5THTA 5G0YA 1C3PA 5EFJD 1C3RA 4BZ7A 4ZUNA 4CQFA 1ZZ3A 4QA3A 5FCWA 5DC5A 5EF7A 4RN0A 4QA7A 4BZ6A 5EFBD 2GH6A 1ZZ0A 2V5WA 3C0YA 3MZ3A 2VQVA 5EFHA 4RN2A 3EWFA 5G12A 4A69A 5D1CA 5THSA 5EFGA 3MZ7A 5FUEA 2VQJA 3ZNSA 5ICNB 5G3WA 5G1BA 5G0IA 5IX0A 5G0GA 5DC7A 5EFKB 3C10A 5BWZA 5D1DA 3C0ZA 1C3SA 4CBTA 4QA6A 4QA4A 5JI5A 2VQWG 5EF8A 3SFFA 1VKGA 4BZ5A 5G17A 4ZUPA 5EEIA 2VCGA 4ZUMA 3EZTA 4ZUQA 4QA0A 3F0RA 5G11A 5A2SA 2VQMA 3MZ6A 5THUA 5EEFA 3Q9BA 1T67A 5IWGA 5EEMA 1W22A 3Q9EA 4BZ8A 5DC6A 4QA1A 3F06A 4ZUOA 2VQOA 3EZPA 3ZNRA 4CBYA 1T64A 4ZURA 5LI3A 5THVA 3Q9FA 4BKXB 3F07A 5G10A 3RQDA 1ZZ1A 5DC8A 5EEKA 5G0XA 3MENA 2VQQA 5G13A 5EENA 4RN1A 5G0JA 4QA5A 5D1BA 3Q9CA 3MAXA 2V5XA 4QA2A 3SFHA 4BZ9A 3EW8A 3MZ4A 5G1AA 4LY1A 1T69A 5G1CA 5EFNA 5G0HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LXZ A;  5THT A;  5G0Y A;  1C3P A;  5EFJ D;  1C3R A;  4BZ7 A;  4ZUN A;  4CQF A;  1ZZ3 A;  4QA3 A;  5FCW A;  5DC5 A;  5EF7 A;  4RN0 A;  4QA7 A;  4BZ6 A;  5EFB D;  2GH6 A;  1ZZ0 A;  2V5W A;  3C0Y A;  3MZ3 A;  2VQV A;  5EFH A;  4RN2 A;  3EWF A;  5G12 A;  4A69 A;  5D1C A;  5THS A;  5EFG A;  3MZ7 A;  5FUE A;  2VQJ A;  3ZNS A;  5ICN B;  5G3W A;  5G1B A;  5G0I A;  5IX0 A;  5G0G A;  5DC7 A;  5EFK B;  3C10 A;  5BWZ A;  5D1D A;  3C0Z A;  1C3S A;  4CBT A;  4QA6 A;  4QA4 A;  5JI5 A;  2VQW G;  5EF8 A;  3SFF A;  1VKG A;  4BZ5 A;  5G17 A;  4ZUP A;  5EEI A;  2VCG A;  4ZUM A;  3EZT A;  4ZUQ A;  4QA0 A;  3F0R A;  5G11 A;  5A2S A;  2VQM A;  3MZ6 A;  5THU A;  5EEF A;  3Q9B A;  1T67 A;  5IWG A;  5EEM A;  1W22 A;  3Q9E A;  4BZ8 A;  5DC6 A;  4QA1 A;  3F06 A;  4ZUO A;  2VQO A;  3EZP A;  3ZNR A;  4CBY A;  1T64 A;  4ZUR A;  5LI3 A;  5THV A;  3Q9F A;  4BKX B;  3F07 A;  5G10 A;  3RQD A;  1ZZ1 A;  5DC8 A;  5EEK A;  5G0X A;  3MEN A;  2VQQ A;  5G13 A;  5EEN A;  4RN1 A;  5G0J A;  4QA5 A;  5D1B A;  3Q9C A;  3MAX A;  2V5X A;  4QA2 A;  3SFH A;  4BZ9 A;  3EW8 A;  3MZ4 A;  5G1A A;  4LY1 A;  1T69 A;  5G1C A;  5EFN A;  5G0H A; 
#chains in the Genus database with same CATH topology
 2EF5 A;  4GWC A;  3TF3 A;  4LXZ A;  1ZPE A;  5THT A;  4FCI A;  5G0Y A;  1C3P A;  5EFJ D;  1C3R A;  4BZ7 A;  4ZUN A;  4CQF A;  1ZZ3 A;  4QA3 A;  5FCW A;  4IE1 A;  5DC5 A;  5HJA A;  5EF7 A;  4RN0 A;  3LP4 A;  2PHA A;  2A0M A;  4QA7 A;  4BZ6 A;  5EFB D;  1WVB A;  1ZZ0 A;  2GH6 A;  2V5W A;  3THJ A;  3C0Y A;  3MZ3 A;  4Q3V A;  2VQV A;  5EFH A;  4RN2 A;  3EWF A;  1P8M A;  5G12 A;  5D1C A;  4A69 A;  1ZPG A;  4IE2 A;  4HWW A;  5THS A;  5EFG A;  3MZ7 A;  1HQH A;  2VQJ A;  5FUE A;  3SJT A;  3ZNS A;  4Q3T A;  5ICN B;  4MYK A;  1D3V A;  5G3W A;  3RLA A;  5G1B A;  5G0I A;  3THE A;  5IX0 A;  4IE3 A;  5G0G A;  1T5G A;  5CEV A;  1HQ5 A;  5DC7 A;  2PLL A;  2ZAV A;  4ZUO A;  4HZE A;  5EFK B;  1P8N A;  3C10 A;  5BWZ A;  4RHJ A;  5D1D A;  4Q3U A;  3C0Z A;  1T4P A;  1C3S A;  3MJL A;  4MYF A;  4CBT A;  3PZL A;  4QA6 A;  1TBH A;  4QA4 A;  5JI5 A;  3DJ8 A;  2CEV A;  3MMR A;  2EIV A;  2VQW G;  3GN0 A;  4GSM A;  5EF8 A;  4Q41 A;  3SFF A;  1VKG A;  1P8O A;  5G17 A;  4BZ5 A;  4ZUP A;  5EEI A;  2VCG A;  4MYL A;  4ZUM A;  3EZT A;  4RHI A;  4ZUQ A;  1P8Q A;  3MFV A;  4QA0 A;  3CEV A;  4RLA A;  1T4S A;  1P8R A;  3F0R A;  4GSV A;  3NIP A;  4Q3S A;  4Q40 A;  5G11 A;  3THH A;  5A2S A;  2VQM A;  3MFW A;  3MZ6 A;  1CEV A;  3E6V A;  3LHL A;  5THU A;  2EF4 A;  3SKK A;  5EEF A;  2RLA A;  1T67 A;  3Q9B A;  5IWG A;  5EEM A;  4IXU A;  3ZNR A;  1W22 A;  3Q9E A;  4RHK A;  1HQX A;  4BZ8 A;  1WOI A;  4QA1 A;  1PQ3 A;  3F06 A;  3EZP A;  2VQO A;  1P8P A;  1T4T A;  5DC6 A;  3NIQ A;  1T64 A;  4G3H A;  4ITY A;  4I06 A;  4Q3R A;  4ZUR A;  3SL0 A;  4CBY A;  4Q3Q A;  3TH7 A;  5LI3 A;  5THV A;  4GSZ A;  5HJ9 A;  3Q9F A;  4BKX B;  3F07 A;  3M1R A;  5G10 A;  5RLA A;  1GQ7 A;  3RQD A;  3GMZ A;  4CEV A;  1ZZ1 A;  4IXV A;  5DC8 A;  4RHQ A;  5EEK A;  1GQ6 A;  4Q42 A;  3SL1 A;  3E8Q A;  4Q3P A;  3F80 A;  5G0X A;  3LP7 A;  3MEN A;  2PHO A;  2VQQ A;  5G13 A;  1WOH A;  5EEN A;  4IU5 A;  4Q3R C;  4IU4 A;  3E6K A;  1WVA A;  4RN1 A;  5G0J A;  3NIO A;  4MXR A;  4QA5 A;  5D1B A;  3Q9C A;  3MAX A;  2V5X A;  1XFK A;  3KV2 A;  4QA2 A;  4RHL A;  4HXQ A;  3SFH A;  4RHM A;  4BZ9 A;  3E9B A;  1T5F A;  3EW8 A;  3MZ4 A;  1TBJ A;  1R1O A;  1P8S A;  5G1A A;  1T4R A;  1HQF A;  4FCK A;  3E8Z A;  4MYN A;  4GWD A;  4DZ4 A;  4IU1 A;  1TA1 A;  4LY1 A;  1T69 A;  1RLA A;  1HQG A;  1TBL A;  4IU0 A;  5G1C A;  5EFN A;  1WOG A;  5G0H A;  2AEB A; 
#chains in the Genus database with same CATH homology
 4LXZ A;  5THT A;  5G0Y A;  1C3P A;  5EFJ D;  1C3R A;  4BZ7 A;  4ZUN A;  4CQF A;  1ZZ3 A;  4QA3 A;  5FCW A;  5DC5 A;  5EF7 A;  4RN0 A;  4QA7 A;  4BZ6 A;  5EFB D;  2GH6 A;  1ZZ0 A;  2V5W A;  3C0Y A;  3MZ3 A;  2VQV A;  5EFH A;  4RN2 A;  3EWF A;  5G12 A;  4A69 A;  5D1C A;  5THS A;  5EFG A;  3MZ7 A;  5FUE A;  2VQJ A;  3ZNS A;  5ICN B;  5G3W A;  5G1B A;  5G0I A;  5IX0 A;  5G0G A;  5DC7 A;  5EFK B;  3C10 A;  5BWZ A;  5D1D A;  3C0Z A;  1C3S A;  4CBT A;  4QA6 A;  4QA4 A;  5JI5 A;  2VQW G;  5EF8 A;  3SFF A;  1VKG A;  4BZ5 A;  5G17 A;  4ZUP A;  5EEI A;  2VCG A;  4ZUM A;  3EZT A;  4ZUQ A;  4QA0 A;  3F0R A;  5G11 A;  5A2S A;  2VQM A;  3MZ6 A;  5THU A;  5EEF A;  3Q9B A;  1T67 A;  5IWG A;  5EEM A;  1W22 A;  3Q9E A;  4BZ8 A;  5DC6 A;  4QA1 A;  3F06 A;  4ZUO A;  2VQO A;  3EZP A;  3ZNR A;  4CBY A;  1T64 A;  4ZUR A;  5LI3 A;  5THV A;  3Q9F A;  4BKX B;  3F07 A;  5G10 A;  3RQD A;  1ZZ1 A;  5DC8 A;  5EEK A;  5G0X A;  3MEN A;  2VQQ A;  5G13 A;  5EEN A;  4RN1 A;  5G0J A;  4QA5 A;  5D1B A;  3Q9C A;  3MAX A;  2V5X A;  4QA2 A;  3SFH A;  4BZ9 A;  3EW8 A;  3MZ4 A;  5G1A A;  4LY1 A;  1T69 A;  5G1C A;  5EFN A;  5G0H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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