5HJAA

Crystal structure of leishmania mexicana arginase in complex with inhibitor abhdp
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
310
structure length
303
Chain Sequence
b'KKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLNDTISVGCAIARCMMGETLLYT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginase
publication title Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
pubmed doi rcsb
source organism Leishmania mexicana
molecule tags Hydrolase
total genus 117
structure length 303
sequence length 310
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2016-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 5hjaA00
3TF3A 1T5GA 1P8RA 3DJ8A 1HQHA 4IE2A 4MYKA 2PHOA 3THEA 4RHMA 1WVAA 1CEVA 5RLAA 1T4PA 3SL1A 4Q41A 3NIQA 1HQGA 1T4TA 3GMZA 5CEVA 2EF5A 4Q3QA 1WOGA 3LP4A 4IU0A 4RHQA 1P8OA 1HQFA 1P8PA 1TBJA 4MYNA 1WOIA 4FCIA 4FCKA 4Q3VA 2PHAA 4GWDA 4RHLA 1P8SA 4Q3UA 4Q40A 1GQ6A 1P8NA 1P8QA 3LP7A 4IXVA 4Q3TA 3NIPA 3F80A 3E6KA 4RHKA 3SJTA 1TBLA 4IU4A 4GSVA 1WOHA 4GSZA 4RLAA 2EIVA 1ZPEA 1T4SA 4DZ4A 4G3HA 3MJLA 1HQ5A 2CEVA 2A0MA 4Q3PA 3NIOA 5HJAA 4GSMA 2ZAVA 4Q42A 4MYFA 1T4RA 1HQXA 4Q3RC 3RLAA 1R1OA 1PQ3A 1ZPGA 4MXRA 4ITYA 3M1RA 4IU1A 1TA1A 3E6VA 3MFVA 4Q3SA 3E8ZA 1RLAA 3PZLA 4IU5A 4HZEA 3CEVA 4HXQA 1XFKA 3MMRA 1D3VA 4HWWA 3KV2A 2RLAA 1WVBA 4IE1A 4MYLA 5HJ9A 4RHJA 2PLLA 4GWCA 3THHA 3LHLA 1T5FA 4IE3A 4CEVA 4RHIA 1TBHA 3THJA 3SL0A 2AEBA 4I06A 3E9BA 3GN0A 3MFWA 3TH7A 3SKKA 4Q3RA 1GQ7A 2EF4A 1P8MA 3E8QA 4IXUA
chains in the Genus database with same CATH superfamily
3TF3A 3SFHA 1T5GA 4QA4A 1P8RA 4QA6A 3DJ8A 1HQHA 4IE2A 4MYKA 2PHOA 5G0YA 3THEA 5DC7A 4RHMA 3ZNRA 1WVAA 1CEVA 1ZZ1A 5RLAA 1T4PA 5G12A 3Q9CA 5EENA 5THSA 3SL1A 5EEKA 4CBYA 5EFNA 4ZUOA 4Q41A 2VQOA 4ZUMA 3NIQA 1HQGA 4BZ7A 1T69A 5THVA 1T4TA 3GMZA 4QA7A 5CEVA 2EF5A 4Q3QA 5EFBD 1WOGA 3LP4A 4IU0A 5G1CA 3C10A 4ZUQA 1ZZ3A 3EW8A 4RHQA 1P8OA 1HQFA 1P8PA 3ZNSA 4LXZA 1TBJA 4MYNA 1WOIA 4FCIA 5EF7A 4BZ8A 3Q9EA 4ZURA 4FCKA 3C0YA 4Q3VA 5THUA 2V5WA 2PHAA 4GWDA 4BZ9A 1ZZ0A 5G13A 5DC8A 2VQVA 4ZUPA 4RHLA 1P8SA 4RN0A 3Q9FA 4Q3UA 2VQMA 4BKXB 4Q40A 1GQ6A 3F0RA 1P8NA 1P8QA 2GH6A 5BWZA 3LP7A 4IXVA 4ZUNA 5G1AA 4Q3TA 3NIPA 5EFKB 3F80A 1T67A 2VQJA 3E6KA 4RHKA 3F06A 5G0GA 3SJTA 1TBLA 4IU4A 4CQFA 4GSVA 5D1CA 1WOHA 4GSZA 4RLAA 2EIVA 1ZPEA 2V5XA 1C3PA 1W22A 2VQWG 5JI5A 1T4SA 4DZ4A 4G3HA 3MJLA 5EFHA 5EFJD 3F07A 1HQ5A 2CEVA 2A0MA 3MZ3A 4Q3PA 3NIOA 5G0JA 5HJAA 2VQQA 4GSMA 2ZAVA 4Q42A 4MYFA 1T4RA 4QA0A 1HQXA 5EEMA 4Q3RC 5EEIA 3RLAA 4BZ5A 1R1OA 5FUEA 1PQ3A 5LI3A 1C3SA 1ZPGA 4MXRA 5IX0A 3Q9BA 4ITYA 3SFFA 3M1RA 4IU1A 1TA1A 3E6VA 3MZ4A 3MFVA 4Q3SA 3E8ZA 1RLAA 3PZLA 4RN2A 5EFGA 4IU5A 3MZ7A 4HZEA 5D1BA 3CEVA 4HXQA 4BZ6A 1XFKA 5A2SA 1VKGA 3MMRA 5ICNB 1D3VA 4HWWA 4QA2A 4RN1A 3MENA 3KV2A 2RLAA 1WVBA 4IE1A 3C0ZA 5IWGA 4MYLA 5D1DA 5HJ9A 5DC6A 5G11A 4RHJA 3MZ6A 1T64A 2PLLA 4GWCA 5THTA 3EWFA 2VCGA 3RQDA 4LY1A 3EZTA 5G0XA 3THHA 4QA3A 3LHLA 5FCWA 4CBTA 1T5FA 4IE3A 5G1BA 5G10A 5EEFA 4CEVA 4RHIA 1TBHA 3THJA 3SL0A 2AEBA 4I06A 3EZPA 3E9BA 3GN0A 3MFWA 5EF8A 3SKKA 3TH7A 5G0IA 4Q3RA 5G0HA 5G17A 1GQ7A 4A69A 2EF4A 5DC5A 3MAXA 1P8MA 3E8QA 5G3WA 4IXUA 1C3RA 4QA5A 4QA1A
chains in the Genus database with same CATH topology
3TF3A 1T5GA 1P8RA 3DJ8A 1HQHA 4IE2A 4MYKA 2PHOA 3THEA 4RHMA 1WVAA 1CEVA 5RLAA 1T4PA 3SL1A 4Q41A 3NIQA 1HQGA 1T4TA 3GMZA 5CEVA 2EF5A 4Q3QA 1WOGA 3LP4A 4IU0A 4RHQA 1P8OA 1HQFA 1P8PA 1TBJA 4MYNA 1WOIA 4FCIA 4FCKA 4Q3VA 2PHAA 4GWDA 4RHLA 1P8SA 4Q3UA 4Q40A 1GQ6A 1P8NA 1P8QA 3LP7A 4IXVA 4Q3TA 3NIPA 3F80A 3E6KA 4RHKA 3SJTA 1TBLA 4IU4A 4GSVA 1WOHA 4GSZA 4RLAA 2EIVA 1ZPEA 1T4SA 4DZ4A 4G3HA 3MJLA 1HQ5A 2CEVA 2A0MA 4Q3PA 3NIOA 5HJAA 4GSMA 2ZAVA 4Q42A 4MYFA 1T4RA 1HQXA 4Q3RC 3RLAA 1R1OA 1PQ3A 1ZPGA 4MXRA 4ITYA 3M1RA 4IU1A 1TA1A 3E6VA 3MFVA 4Q3SA 3E8ZA 1RLAA 3PZLA 4IU5A 4HZEA 3CEVA 4HXQA 1XFKA 3MMRA 1D3VA 4HWWA 3KV2A 2RLAA 1WVBA 4IE1A 4MYLA 5HJ9A 4RHJA 2PLLA 4GWCA 3THHA 3LHLA 1T5FA 4IE3A 4CEVA 4RHIA 1TBHA 3THJA 3SL0A 2AEBA 4I06A 3E9BA 3GN0A 3MFWA 3TH7A 3SKKA 4Q3RA 1GQ7A 2EF4A 1P8MA 3E8QA 4IXUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TF3 A;  1T5G A;  1P8R A;  3DJ8 A;  1HQH A;  4IE2 A;  4MYK A;  2PHO A;  3THE A;  4RHM A;  1WVA A;  1CEV A;  5RLA A;  1T4P A;  3SL1 A;  4Q41 A;  3NIQ A;  1HQG A;  1T4T A;  3GMZ A;  5CEV A;  2EF5 A;  4Q3Q A;  1WOG A;  3LP4 A;  4IU0 A;  4RHQ A;  1P8O A;  1HQF A;  1P8P A;  1TBJ A;  4MYN A;  1WOI A;  4FCI A;  4FCK A;  4Q3V A;  2PHA A;  4GWD A;  4RHL A;  1P8S A;  4Q3U A;  4Q40 A;  1GQ6 A;  1P8N A;  1P8Q A;  3LP7 A;  4IXV A;  4Q3T A;  3NIP A;  3F80 A;  3E6K A;  4RHK A;  3SJT A;  1TBL A;  4IU4 A;  4GSV A;  1WOH A;  4GSZ A;  4RLA A;  2EIV A;  1ZPE A;  1T4S A;  4DZ4 A;  4G3H A;  3MJL A;  1HQ5 A;  2CEV A;  2A0M A;  4Q3P A;  3NIO A;  5HJA A;  4GSM A;  2ZAV A;  4Q42 A;  4MYF A;  1T4R A;  1HQX A;  4Q3R C;  3RLA A;  1R1O A;  1PQ3 A;  1ZPG A;  4MXR A;  4ITY A;  3M1R A;  4IU1 A;  1TA1 A;  3E6V A;  3MFV A;  4Q3S A;  3E8Z A;  1RLA A;  3PZL A;  4IU5 A;  4HZE A;  3CEV A;  4HXQ A;  1XFK A;  3MMR A;  1D3V A;  4HWW A;  3KV2 A;  2RLA A;  1WVB A;  4IE1 A;  4MYL A;  5HJ9 A;  4RHJ A;  2PLL A;  4GWC A;  3THH A;  3LHL A;  1T5F A;  4IE3 A;  4CEV A;  4RHI A;  1TBH A;  3THJ A;  3SL0 A;  2AEB A;  4I06 A;  3E9B A;  3GN0 A;  3MFW A;  3TH7 A;  3SKK A;  4Q3R A;  1GQ7 A;  2EF4 A;  1P8M A;  3E8Q A;  4IXU A; 
#chains in the Genus database with same CATH topology
 3TF3 A;  3SFH A;  1T5G A;  4QA4 A;  1P8R A;  4QA6 A;  3DJ8 A;  1HQH A;  4IE2 A;  4MYK A;  2PHO A;  5G0Y A;  3THE A;  5DC7 A;  4RHM A;  3ZNR A;  1WVA A;  1CEV A;  1ZZ1 A;  5RLA A;  1T4P A;  5G12 A;  3Q9C A;  5EEN A;  5THS A;  3SL1 A;  5EEK A;  4CBY A;  5EFN A;  4ZUO A;  4Q41 A;  2VQO A;  4ZUM A;  3NIQ A;  1HQG A;  4BZ7 A;  1T69 A;  5THV A;  1T4T A;  3GMZ A;  4QA7 A;  5CEV A;  2EF5 A;  4Q3Q A;  5EFB D;  1WOG A;  3LP4 A;  4IU0 A;  5G1C A;  3C10 A;  4ZUQ A;  1ZZ3 A;  3EW8 A;  4RHQ A;  1P8O A;  1HQF A;  1P8P A;  3ZNS A;  4LXZ A;  1TBJ A;  4MYN A;  1WOI A;  4FCI A;  5EF7 A;  4BZ8 A;  3Q9E A;  4ZUR A;  4FCK A;  3C0Y A;  4Q3V A;  5THU A;  2V5W A;  2PHA A;  4GWD A;  4BZ9 A;  1ZZ0 A;  5G13 A;  5DC8 A;  2VQV A;  4ZUP A;  4RHL A;  1P8S A;  4RN0 A;  3Q9F A;  4Q3U A;  2VQM A;  4BKX B;  4Q40 A;  1GQ6 A;  3F0R A;  1P8N A;  1P8Q A;  2GH6 A;  5BWZ A;  3LP7 A;  4IXV A;  4ZUN A;  5G1A A;  4Q3T A;  3NIP A;  5EFK B;  3F80 A;  1T67 A;  2VQJ A;  3E6K A;  4RHK A;  3F06 A;  5G0G A;  3SJT A;  1TBL A;  4IU4 A;  4CQF A;  4GSV A;  5D1C A;  1WOH A;  4GSZ A;  4RLA A;  2EIV A;  1ZPE A;  2V5X A;  1C3P A;  1W22 A;  2VQW G;  5JI5 A;  1T4S A;  4DZ4 A;  4G3H A;  3MJL A;  5EFH A;  5EFJ D;  3F07 A;  1HQ5 A;  2CEV A;  2A0M A;  3MZ3 A;  4Q3P A;  3NIO A;  5G0J A;  5HJA A;  2VQQ A;  4GSM A;  2ZAV A;  4Q42 A;  4MYF A;  1T4R A;  4QA0 A;  1HQX A;  5EEM A;  4Q3R C;  5EEI A;  3RLA A;  4BZ5 A;  1R1O A;  5FUE A;  1PQ3 A;  5LI3 A;  1C3S A;  1ZPG A;  4MXR A;  5IX0 A;  3Q9B A;  4ITY A;  3SFF A;  3M1R A;  4IU1 A;  1TA1 A;  3E6V A;  3MZ4 A;  3MFV A;  4Q3S A;  3E8Z A;  1RLA A;  3PZL A;  4RN2 A;  5EFG A;  4IU5 A;  3MZ7 A;  4HZE A;  5D1B A;  3CEV A;  4HXQ A;  4BZ6 A;  1XFK A;  5A2S A;  1VKG A;  3MMR A;  5ICN B;  1D3V A;  4HWW A;  4QA2 A;  4RN1 A;  3MEN A;  3KV2 A;  2RLA A;  1WVB A;  4IE1 A;  3C0Z A;  5IWG A;  4MYL A;  5D1D A;  5HJ9 A;  5DC6 A;  5G11 A;  4RHJ A;  3MZ6 A;  1T64 A;  2PLL A;  4GWC A;  5THT A;  3EWF A;  2VCG A;  3RQD A;  4LY1 A;  3EZT A;  5G0X A;  3THH A;  4QA3 A;  3LHL A;  5FCW A;  4CBT A;  1T5F A;  4IE3 A;  5G1B A;  5G10 A;  5EEF A;  4CEV A;  4RHI A;  1TBH A;  3THJ A;  3SL0 A;  2AEB A;  4I06 A;  3EZP A;  3E9B A;  3GN0 A;  3MFW A;  5EF8 A;  3SKK A;  3TH7 A;  5G0I A;  4Q3R A;  5G0H A;  5G17 A;  1GQ7 A;  4A69 A;  2EF4 A;  5DC5 A;  3MAX A;  1P8M A;  3E8Q A;  5G3W A;  4IXU A;  1C3R A;  4QA5 A;  4QA1 A; 
#chains in the Genus database with same CATH homology
 3TF3 A;  1T5G A;  1P8R A;  3DJ8 A;  1HQH A;  4IE2 A;  4MYK A;  2PHO A;  3THE A;  4RHM A;  1WVA A;  1CEV A;  5RLA A;  1T4P A;  3SL1 A;  4Q41 A;  3NIQ A;  1HQG A;  1T4T A;  3GMZ A;  5CEV A;  2EF5 A;  4Q3Q A;  1WOG A;  3LP4 A;  4IU0 A;  4RHQ A;  1P8O A;  1HQF A;  1P8P A;  1TBJ A;  4MYN A;  1WOI A;  4FCI A;  4FCK A;  4Q3V A;  2PHA A;  4GWD A;  4RHL A;  1P8S A;  4Q3U A;  4Q40 A;  1GQ6 A;  1P8N A;  1P8Q A;  3LP7 A;  4IXV A;  4Q3T A;  3NIP A;  3F80 A;  3E6K A;  4RHK A;  3SJT A;  1TBL A;  4IU4 A;  4GSV A;  1WOH A;  4GSZ A;  4RLA A;  2EIV A;  1ZPE A;  1T4S A;  4DZ4 A;  4G3H A;  3MJL A;  1HQ5 A;  2CEV A;  2A0M A;  4Q3P A;  3NIO A;  5HJA A;  4GSM A;  2ZAV A;  4Q42 A;  4MYF A;  1T4R A;  1HQX A;  4Q3R C;  3RLA A;  1R1O A;  1PQ3 A;  1ZPG A;  4MXR A;  4ITY A;  3M1R A;  4IU1 A;  1TA1 A;  3E6V A;  3MFV A;  4Q3S A;  3E8Z A;  1RLA A;  3PZL A;  4IU5 A;  4HZE A;  3CEV A;  4HXQ A;  1XFK A;  3MMR A;  1D3V A;  4HWW A;  3KV2 A;  2RLA A;  1WVB A;  4IE1 A;  4MYL A;  5HJ9 A;  4RHJ A;  2PLL A;  4GWC A;  3THH A;  3LHL A;  1T5F A;  4IE3 A;  4CEV A;  4RHI A;  1TBH A;  3THJ A;  3SL0 A;  2AEB A;  4I06 A;  3E9B A;  3GN0 A;  3MFW A;  3TH7 A;  3SKK A;  4Q3R A;  1GQ7 A;  2EF4 A;  1P8M A;  3E8Q A;  4IXU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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