1RLAA

Three-dimensional structure of rat liver arginase, the binuclear manganese metalloenzyme of the urea cycle
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
314
structure length
314
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a unique binuclear manganese cluster in arginase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ARGINASE
total genus 101
structure length 314
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1996-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1rlaA00
3SJTA 1HQ5A 1P8RA 3KV2A 4GWDA 1ZPEA 4IU0A 1WOGA 4GSZA 1WVAA 3F80A 4RHQA 4IE1A 3SL0A 4Q3RC 1P8MA 4IXUA 2PLLA 1TBJA 1P8QA 3NIPA 1HQFA 1T4RA 4FCKA 1HQGA 1CEVA 4RHLA 4Q3QA 3GMZA 4GWCA 4IE2A 4ITYA 3E8QA 4IU5A 3NIQA 3E8ZA 4RHIA 4Q3PA 4DZ4A 1PQ3A 3DJ8A 1HQXA 4IU4A 4Q3UA 4Q3VA 5HJAA 4Q3RA 1XFKA 3TF3A 3SKKA 4Q3TA 3MJLA 3THEA 1GQ6A 4IXVA 1P8PA 3M1RA 1P8SA 3NIOA 4IU1A 4RHJA 3CEVA 1WVBA 1T4SA 3LP4A 5RLAA 2EIVA 1T4PA 3LHLA 4MXRA 4HXQA 3MFWA 4MYNA 3MFVA 1TBHA 1GQ7A 3E6VA 3THJA 5CEVA 2CEVA 4Q42A 4RLAA 2RLAA 2A0MA 1P8OA 4HWWA 3SL1A 3LP7A 4RHKA 1T5GA 1WOIA 2PHAA 4GSVA 3E6KA 1RLAA 1TA1A 2EF5A 4FCIA 5HJ9A 1P8NA 4MYFA 3MMRA 1TBLA 2PHOA 1D3VA 4I06A 4RHMA 3TH7A 4Q41A 4G3HA 4CEVA 1ZPGA 3THHA 1T4TA 4HZEA 2AEBA 4Q3SA 4Q40A 1T5FA 4MYLA 2ZAVA 3E9BA 3PZLA 4IE3A 3GN0A 4MYKA 3RLAA 1HQHA 2EF4A 1R1OA 4GSMA 1WOHA
chains in the Genus database with same CATH superfamily
3SJTA 1HQ5A 1P8RA 3KV2A 4GWDA 1ZPEA 4IU0A 4Q40A 5EEMA 1WOGA 4GSZA 1WVAA 3EZPA 5EFHA 3F80A 2VQVA 4RHQA 2VCGA 4IE1A 3SL0A 4Q3RC 5EFBD 5THVA 3F06A 3F07A 1P8MA 4IXUA 4ZUPA 2PLLA 4LY1A 4A69A 5EEFA 5EFJD 3MENA 1TBJA 1P8QA 5EEKA 2VQMA 3NIPA 1HQFA 5EF7A 3ZNSA 5A2SA 1T4RA 4LXZA 5G0JA 1T67A 4FCKA 1HQGA 4ZUQA 1CEVA 1ZZ0A 4RHLA 5G3WA 4Q3QA 3Q9BA 5G17A 4QA5A 5IWGA 1VKGA 1ZZ1A 3GMZA 4GWCA 4IE2A 4QA3A 4ITYA 1T64A 3E8QA 3EW8A 4IU5A 3NIQA 3E8ZA 4QA1A 4RHIA 5THTA 4Q3PA 4DZ4A 1PQ3A 3DJ8A 1HQXA 2VQWG 4IU4A 4Q3UA 4Q3VA 4BZ5A 5HJAA 3C0YA 4Q3RA 2GH6A 4CQFA 1XFKA 3SFHA 5DC5A 3TF3A 3SKKA 4Q3TA 3MJLA 3EWFA 2V5XA 3Q9EA 3RQDA 5G13A 3THEA 1GQ6A 4IXVA 5G11A 3MZ3A 5FCWA 1P8PA 3M1RA 1P8SA 3MZ7A 2VQOA 3NIOA 4IU1A 5G1AA 5G10A 4CBYA 4RHJA 2VQQA 3CEVA 1WVBA 1T4SA 3LP4A 5RLAA 2EIVA 5D1DA 1T4PA 5EFNA 3RLAA 1T69A 3EZTA 4RN0A 3LHLA 4MXRA 4QA0A 4HXQA 3MFWA 3MZ4A 4MYNA 3MFVA 1TBHA 4BZ9A 5BWZA 1GQ7A 3E6VA 3THJA 5CEVA 3F0RA 4BZ8A 4ZURA 2CEVA 2V5WA 5EEIA 4Q42A 4QA2A 3MAXA 2RLAA 4RLAA 4ZUMA 4QA6A 2A0MA 1P8OA 3Q9CA 4HWWA 5G0XA 3LP7A 5EENA 5G0GA 3SL1A 4RHKA 1T5GA 4BKXB 2VQJA 1WOIA 2PHAA 4ZUOA 4GSVA 4RN2A 3MZ6A 5G1CA 5D1CA 4ZUNA 5THSA 5IX0A 4CBTA 3E6KA 1RLAA 1TA1A 2EF5A 4FCIA 5EFKB 5HJ9A 5DC6A 3C0ZA 5THUA 1P8NA 4BZ7A 4MYFA 5JI5A 5LI3A 3MMRA 1TBLA 3C10A 2PHOA 1D3VA 4I06A 4RN1A 4RHMA 5G1BA 5ICNB 3TH7A 4BZ6A 4Q41A 4G3HA 4CEVA 1C3PA 1ZPGA 3SFFA 5G0HA 3THHA 4QA4A 5EFGA 1T4TA 5EF8A 4HZEA 1ZZ3A 3ZNRA 5DC7A 2AEBA 4Q3SA 3Q9FA 1C3RA 1C3SA 1T5FA 2ZAVA 3E9BA 3PZLA 1W22A 3GN0A 4IE3A 4MYLA 1HQHA 4MYKA 2EF4A 1R1OA 4GSMA 5DC8A 5G0IA 4QA7A 5D1BA 5G0YA 5G12A 5FUEA 1WOHA
chains in the Genus database with same CATH topology
3SJTA 1HQ5A 1P8RA 3KV2A 4GWDA 1ZPEA 4IU0A 1WOGA 4GSZA 1WVAA 3F80A 4RHQA 4IE1A 3SL0A 4Q3RC 1P8MA 4IXUA 2PLLA 1TBJA 1P8QA 3NIPA 1HQFA 1T4RA 4FCKA 1HQGA 1CEVA 4RHLA 4Q3QA 3GMZA 4GWCA 4IE2A 4ITYA 3E8QA 4IU5A 3NIQA 3E8ZA 4RHIA 4Q3PA 4DZ4A 1PQ3A 3DJ8A 1HQXA 4IU4A 4Q3UA 4Q3VA 5HJAA 4Q3RA 1XFKA 3TF3A 3SKKA 4Q3TA 3MJLA 3THEA 1GQ6A 4IXVA 1P8PA 3M1RA 1P8SA 3NIOA 4IU1A 4RHJA 3CEVA 1WVBA 1T4SA 3LP4A 5RLAA 2EIVA 1T4PA 3LHLA 4MXRA 4HXQA 3MFWA 4MYNA 3MFVA 1TBHA 1GQ7A 3E6VA 3THJA 5CEVA 2CEVA 4Q42A 4RLAA 2RLAA 2A0MA 1P8OA 4HWWA 3SL1A 3LP7A 4RHKA 1T5GA 1WOIA 2PHAA 4GSVA 3E6KA 1RLAA 1TA1A 2EF5A 4FCIA 5HJ9A 1P8NA 4MYFA 3MMRA 1TBLA 2PHOA 1D3VA 4I06A 4RHMA 3TH7A 4Q41A 4G3HA 4CEVA 1ZPGA 3THHA 1T4TA 4HZEA 2AEBA 4Q3SA 4Q40A 1T5FA 4MYLA 2ZAVA 3E9BA 3PZLA 4IE3A 3GN0A 4MYKA 3RLAA 1HQHA 2EF4A 1R1OA 4GSMA 1WOHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SJT A;  1HQ5 A;  1P8R A;  3KV2 A;  4GWD A;  1ZPE A;  4IU0 A;  1WOG A;  4GSZ A;  1WVA A;  3F80 A;  4RHQ A;  4IE1 A;  3SL0 A;  4Q3R C;  1P8M A;  4IXU A;  2PLL A;  1TBJ A;  1P8Q A;  3NIP A;  1HQF A;  1T4R A;  4FCK A;  1HQG A;  1CEV A;  4RHL A;  4Q3Q A;  3GMZ A;  4GWC A;  4IE2 A;  4ITY A;  3E8Q A;  4IU5 A;  3NIQ A;  3E8Z A;  4RHI A;  4Q3P A;  4DZ4 A;  1PQ3 A;  3DJ8 A;  1HQX A;  4IU4 A;  4Q3U A;  4Q3V A;  5HJA A;  4Q3R A;  1XFK A;  3TF3 A;  3SKK A;  4Q3T A;  3MJL A;  3THE A;  1GQ6 A;  4IXV A;  1P8P A;  3M1R A;  1P8S A;  3NIO A;  4IU1 A;  4RHJ A;  3CEV A;  1WVB A;  1T4S A;  3LP4 A;  5RLA A;  2EIV A;  1T4P A;  3LHL A;  4MXR A;  4HXQ A;  3MFW A;  4MYN A;  3MFV A;  1TBH A;  1GQ7 A;  3E6V A;  3THJ A;  5CEV A;  2CEV A;  4Q42 A;  4RLA A;  2RLA A;  2A0M A;  1P8O A;  4HWW A;  3SL1 A;  3LP7 A;  4RHK A;  1T5G A;  1WOI A;  2PHA A;  4GSV A;  3E6K A;  1RLA A;  1TA1 A;  2EF5 A;  4FCI A;  5HJ9 A;  1P8N A;  4MYF A;  3MMR A;  1TBL A;  2PHO A;  1D3V A;  4I06 A;  4RHM A;  3TH7 A;  4Q41 A;  4G3H A;  4CEV A;  1ZPG A;  3THH A;  1T4T A;  4HZE A;  2AEB A;  4Q3S A;  4Q40 A;  1T5F A;  4MYL A;  2ZAV A;  3E9B A;  3PZL A;  4IE3 A;  3GN0 A;  4MYK A;  3RLA A;  1HQH A;  2EF4 A;  1R1O A;  4GSM A;  1WOH A; 
#chains in the Genus database with same CATH topology
 3SJT A;  1HQ5 A;  1P8R A;  3KV2 A;  4GWD A;  1ZPE A;  4IU0 A;  4Q40 A;  5EEM A;  1WOG A;  4GSZ A;  1WVA A;  3EZP A;  5EFH A;  3F80 A;  2VQV A;  4RHQ A;  2VCG A;  4IE1 A;  3SL0 A;  4Q3R C;  5EFB D;  5THV A;  3F06 A;  3F07 A;  1P8M A;  4IXU A;  4ZUP A;  2PLL A;  4LY1 A;  4A69 A;  5EEF A;  5EFJ D;  3MEN A;  1TBJ A;  1P8Q A;  5EEK A;  2VQM A;  3NIP A;  1HQF A;  5EF7 A;  3ZNS A;  5A2S A;  1T4R A;  4LXZ A;  5G0J A;  1T67 A;  4FCK A;  1HQG A;  4ZUQ A;  1CEV A;  1ZZ0 A;  4RHL A;  5G3W A;  4Q3Q A;  3Q9B A;  5G17 A;  4QA5 A;  5IWG A;  1VKG A;  1ZZ1 A;  3GMZ A;  4GWC A;  4IE2 A;  4QA3 A;  4ITY A;  1T64 A;  3E8Q A;  3EW8 A;  4IU5 A;  3NIQ A;  3E8Z A;  4QA1 A;  4RHI A;  5THT A;  4Q3P A;  4DZ4 A;  1PQ3 A;  3DJ8 A;  1HQX A;  2VQW G;  4IU4 A;  4Q3U A;  4Q3V A;  4BZ5 A;  5HJA A;  3C0Y A;  4Q3R A;  2GH6 A;  4CQF A;  1XFK A;  3SFH A;  5DC5 A;  3TF3 A;  3SKK A;  4Q3T A;  3MJL A;  3EWF A;  2V5X A;  3Q9E A;  3RQD A;  5G13 A;  3THE A;  1GQ6 A;  4IXV A;  5G11 A;  3MZ3 A;  5FCW A;  1P8P A;  3M1R A;  1P8S A;  3MZ7 A;  2VQO A;  3NIO A;  4IU1 A;  5G1A A;  5G10 A;  4CBY A;  4RHJ A;  2VQQ A;  3CEV A;  1WVB A;  1T4S A;  3LP4 A;  5RLA A;  2EIV A;  5D1D A;  1T4P A;  5EFN A;  3RLA A;  1T69 A;  3EZT A;  4RN0 A;  3LHL A;  4MXR A;  4QA0 A;  4HXQ A;  3MFW A;  3MZ4 A;  4MYN A;  3MFV A;  1TBH A;  4BZ9 A;  5BWZ A;  1GQ7 A;  3E6V A;  3THJ A;  5CEV A;  3F0R A;  4BZ8 A;  4ZUR A;  2CEV A;  2V5W A;  5EEI A;  4Q42 A;  4QA2 A;  3MAX A;  2RLA A;  4RLA A;  4ZUM A;  4QA6 A;  2A0M A;  1P8O A;  3Q9C A;  4HWW A;  5G0X A;  3LP7 A;  5EEN A;  5G0G A;  3SL1 A;  4RHK A;  1T5G A;  4BKX B;  2VQJ A;  1WOI A;  2PHA A;  4ZUO A;  4GSV A;  4RN2 A;  3MZ6 A;  5G1C A;  5D1C A;  4ZUN A;  5THS A;  5IX0 A;  4CBT A;  3E6K A;  1RLA A;  1TA1 A;  2EF5 A;  4FCI A;  5EFK B;  5HJ9 A;  5DC6 A;  3C0Z A;  5THU A;  1P8N A;  4BZ7 A;  4MYF A;  5JI5 A;  5LI3 A;  3MMR A;  1TBL A;  3C10 A;  2PHO A;  1D3V A;  4I06 A;  4RN1 A;  4RHM A;  5G1B A;  5ICN B;  3TH7 A;  4BZ6 A;  4Q41 A;  4G3H A;  4CEV A;  1C3P A;  1ZPG A;  3SFF A;  5G0H A;  3THH A;  4QA4 A;  5EFG A;  1T4T A;  5EF8 A;  4HZE A;  1ZZ3 A;  3ZNR A;  5DC7 A;  2AEB A;  4Q3S A;  3Q9F A;  1C3R A;  1C3S A;  1T5F A;  2ZAV A;  3E9B A;  3PZL A;  1W22 A;  3GN0 A;  4IE3 A;  4MYL A;  1HQH A;  4MYK A;  2EF4 A;  1R1O A;  4GSM A;  5DC8 A;  5G0I A;  4QA7 A;  5D1B A;  5G0Y A;  5G12 A;  5FUE A;  1WOH A; 
#chains in the Genus database with same CATH homology
 3SJT A;  1HQ5 A;  1P8R A;  3KV2 A;  4GWD A;  1ZPE A;  4IU0 A;  1WOG A;  4GSZ A;  1WVA A;  3F80 A;  4RHQ A;  4IE1 A;  3SL0 A;  4Q3R C;  1P8M A;  4IXU A;  2PLL A;  1TBJ A;  1P8Q A;  3NIP A;  1HQF A;  1T4R A;  4FCK A;  1HQG A;  1CEV A;  4RHL A;  4Q3Q A;  3GMZ A;  4GWC A;  4IE2 A;  4ITY A;  3E8Q A;  4IU5 A;  3NIQ A;  3E8Z A;  4RHI A;  4Q3P A;  4DZ4 A;  1PQ3 A;  3DJ8 A;  1HQX A;  4IU4 A;  4Q3U A;  4Q3V A;  5HJA A;  4Q3R A;  1XFK A;  3TF3 A;  3SKK A;  4Q3T A;  3MJL A;  3THE A;  1GQ6 A;  4IXV A;  1P8P A;  3M1R A;  1P8S A;  3NIO A;  4IU1 A;  4RHJ A;  3CEV A;  1WVB A;  1T4S A;  3LP4 A;  5RLA A;  2EIV A;  1T4P A;  3LHL A;  4MXR A;  4HXQ A;  3MFW A;  4MYN A;  3MFV A;  1TBH A;  1GQ7 A;  3E6V A;  3THJ A;  5CEV A;  2CEV A;  4Q42 A;  4RLA A;  2RLA A;  2A0M A;  1P8O A;  4HWW A;  3SL1 A;  3LP7 A;  4RHK A;  1T5G A;  1WOI A;  2PHA A;  4GSV A;  3E6K A;  1RLA A;  1TA1 A;  2EF5 A;  4FCI A;  5HJ9 A;  1P8N A;  4MYF A;  3MMR A;  1TBL A;  2PHO A;  1D3V A;  4I06 A;  4RHM A;  3TH7 A;  4Q41 A;  4G3H A;  4CEV A;  1ZPG A;  3THH A;  1T4T A;  4HZE A;  2AEB A;  4Q3S A;  4Q40 A;  1T5F A;  4MYL A;  2ZAV A;  3E9B A;  3PZL A;  4IE3 A;  3GN0 A;  4MYK A;  3RLA A;  1HQH A;  2EF4 A;  1R1O A;  4GSM A;  1WOH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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