1RLAA

Three-dimensional structure of rat liver arginase, the binuclear manganese metalloenzyme of the urea cycle
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
314
structure length
314
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a unique binuclear manganese cluster in arginase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords ARGINASE
total genus 101
structure length 314
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1996-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1rlaA00
3KV2A 3MMRA 1HQXA 3MFWA 4GSMA 4HWWA 4ITYA 4HZEA 4MYLA 4GWCA 4Q40A 3NIPA 1P8PA 5RLAA 4FCIA 4IXUA 4CEVA 3DJ8A 3E6KA 4Q3UA 4RHJA 3MFVA 1T4PA 1ZPEA 1P8NA 4IE2A 1CEVA 3TF3A 3E6VA 5HJ9A 4IU0A 2AEBA 2CEVA 1TA1A 4Q41A 4Q3QA 1D3VA 4IE3A 4RHIA 3PZLA 4Q3RC 3RLAA 1WOHA 2PHOA 4Q3PA 4RHKA 3THHA 1P8SA 1HQGA 4IU5A 3E8QA 2RLAA 1RLAA 3SL0A 1GQ6A 5HJAA 3F80A 4IXVA 4GSZA 4GWDA 2EF5A 1HQFA 1P8MA 2EF4A 4Q3VA 3SKKA 1ZPGA 2A0MA 1R1OA 1T5FA 4GSVA 3CEVA 1WVAA 4HXQA 4Q3TA 4RLAA 4RHQA 1P8QA 4IU4A 3SL1A 3NIOA 1HQ5A 4MXRA 4RHMA 1T4TA 3GMZA 4MYFA 1PQ3A 4MYNA 1HQHA 4RHLA 3SJTA 1WVBA 3GN0A 2ZAVA 3THJA 4Q42A 4IE1A 3E9BA 1P8OA 5CEVA 3LHLA 3THEA 2PHAA 4DZ4A 3M1RA 3LP4A 1WOIA 4I06A 1GQ7A 1T4RA 3TH7A 3LP7A 3NIQA 4IU1A 3E8ZA 1P8RA 1T4SA 1TBHA 4Q3SA 4MYKA 1XFKA 4FCKA 3MJLA 1TBLA 4Q3RA 1TBJA 2EIVA 2PLLA 1T5GA 4G3HA 1WOGA
chains in the Genus database with same CATH superfamily
1C3PA 3KV2A 3MMRA 1HQXA 3MFWA 4GSMA 4HWWA 4ITYA 4HZEA 4MYLA 5EEFA 4GWCA 4Q40A 5G0XA 3NIPA 4ZURA 1P8PA 5RLAA 4FCIA 1W22A 4BZ8A 5FUEA 4IXUA 2VQOA 3C10A 4CEVA 3DJ8A 5G1AA 3E6KA 4Q3UA 4RHJA 5G17A 3MFVA 3MZ3A 1T4PA 4ZUQA 5EEIA 1ZPEA 4LY1A 3Q9EA 3Q9BA 1P8NA 5DC7A 4IE2A 4ZUNA 1CEVA 3TF3A 3E6VA 5G13A 3MAXA 5HJ9A 3Q9FA 4QA0A 5D1CA 4CBTA 4IU0A 2AEBA 4RN0A 5LI3A 2CEVA 1TA1A 4Q41A 5THSA 4Q3QA 3F07A 1D3VA 5ICNB 4IE3A 4RHIA 2VCGA 5G1BA 4BZ9A 3C0ZA 5THTA 4QA7A 3PZLA 4Q3RC 5IWGA 5G0IA 1ZZ0A 1WOHA 3RLAA 2PHOA 4Q3PA 3C0YA 4RHKA 5D1BA 1ZZ1A 3THHA 1P8SA 1HQGA 1VKGA 5EEKA 4ZUOA 4IU5A 5DC6A 5EFKB 3SFHA 4CBYA 4QA6A 2V5XA 3E8QA 4QA2A 5G0JA 5IX0A 4CQFA 3Q9CA 2RLAA 5G1CA 1RLAA 3SL0A 1GQ6A 3F06A 3F0RA 3F80A 3ZNSA 5HJAA 4IXVA 4QA3A 5BWZA 1T64A 4GSZA 2VQQA 4GWDA 2EF5A 1HQFA 1P8MA 2EF4A 4Q3VA 5EFJD 3SKKA 3EWFA 5D1DA 1ZPGA 2A0MA 2VQWG 3EW8A 3RQDA 2V5WA 5EF7A 3MENA 5EFNA 2VQMA 4QA5A 5EEMA 4A69A 1R1OA 1T5FA 4GSVA 3CEVA 1WVAA 4HXQA 4Q3TA 4RLAA 3EZTA 4RHQA 5A2SA 1P8QA 5G11A 2VQVA 4IU4A 5G0GA 4QA4A 3SL1A 3NIOA 1HQ5A 4MXRA 4RHMA 1T4TA 3GMZA 5G10A 3ZNRA 1C3SA 1T69A 4MYFA 5EFBD 4BZ5A 1PQ3A 3MZ6A 1HQHA 4MYNA 4RHLA 3EZPA 3SJTA 1WVBA 3GN0A 5FCWA 5THVA 2ZAVA 3THJA 4Q42A 2VQJA 2GH6A 4IE1A 3E9BA 1P8OA 5G0HA 4QA1A 5G0YA 5CEVA 3LHLA 1T67A 3THEA 2PHAA 4RN2A 3MZ4A 5DC5A 4DZ4A 3M1RA 4LXZA 3LP4A 1WOIA 4I06A 5EFHA 5G12A 4BKXB 4BZ6A 1GQ7A 1T4RA 5EFGA 3TH7A 5THUA 3LP7A 3NIQA 4IU1A 4RN1A 5DC8A 5G3WA 1ZZ3A 3E8ZA 1C3RA 4BZ7A 1P8RA 5JI5A 1T4SA 1TBHA 4ZUPA 4Q3SA 5EF8A 4MYKA 1XFKA 4FCKA 4ZUMA 3MZ7A 3MJLA 1TBLA 4Q3RA 1TBJA 2EIVA 3SFFA 5EENA 2PLLA 1T5GA 4G3HA 1WOGA
chains in the Genus database with same CATH topology
3KV2A 3MMRA 1HQXA 3MFWA 4GSMA 4HWWA 4ITYA 4HZEA 4MYLA 4GWCA 4Q40A 3NIPA 1P8PA 5RLAA 4FCIA 4IXUA 4CEVA 3DJ8A 3E6KA 4Q3UA 4RHJA 3MFVA 1T4PA 1ZPEA 1P8NA 4IE2A 1CEVA 3TF3A 3E6VA 5HJ9A 4IU0A 2AEBA 2CEVA 1TA1A 4Q41A 4Q3QA 1D3VA 4IE3A 4RHIA 3PZLA 4Q3RC 3RLAA 1WOHA 2PHOA 4Q3PA 4RHKA 3THHA 1P8SA 1HQGA 4IU5A 3E8QA 2RLAA 1RLAA 3SL0A 1GQ6A 5HJAA 3F80A 4IXVA 4GSZA 4GWDA 2EF5A 1HQFA 1P8MA 2EF4A 4Q3VA 3SKKA 1ZPGA 2A0MA 1R1OA 1T5FA 4GSVA 3CEVA 1WVAA 4HXQA 4Q3TA 4RLAA 4RHQA 1P8QA 4IU4A 3SL1A 3NIOA 1HQ5A 4MXRA 4RHMA 1T4TA 3GMZA 4MYFA 1PQ3A 4MYNA 1HQHA 4RHLA 3SJTA 1WVBA 3GN0A 2ZAVA 3THJA 4Q42A 4IE1A 3E9BA 1P8OA 5CEVA 3LHLA 3THEA 2PHAA 4DZ4A 3M1RA 3LP4A 1WOIA 4I06A 1GQ7A 1T4RA 3TH7A 3LP7A 3NIQA 4IU1A 3E8ZA 1P8RA 1T4SA 1TBHA 4Q3SA 4MYKA 1XFKA 4FCKA 3MJLA 1TBLA 4Q3RA 1TBJA 2EIVA 2PLLA 1T5GA 4G3HA 1WOGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KV2 A;  3MMR A;  1HQX A;  3MFW A;  4GSM A;  4HWW A;  4ITY A;  4HZE A;  4MYL A;  4GWC A;  4Q40 A;  3NIP A;  1P8P A;  5RLA A;  4FCI A;  4IXU A;  4CEV A;  3DJ8 A;  3E6K A;  4Q3U A;  4RHJ A;  3MFV A;  1T4P A;  1ZPE A;  1P8N A;  4IE2 A;  1CEV A;  3TF3 A;  3E6V A;  5HJ9 A;  4IU0 A;  2AEB A;  2CEV A;  1TA1 A;  4Q41 A;  4Q3Q A;  1D3V A;  4IE3 A;  4RHI A;  3PZL A;  4Q3R C;  3RLA A;  1WOH A;  2PHO A;  4Q3P A;  4RHK A;  3THH A;  1P8S A;  1HQG A;  4IU5 A;  3E8Q A;  2RLA A;  1RLA A;  3SL0 A;  1GQ6 A;  5HJA A;  3F80 A;  4IXV A;  4GSZ A;  4GWD A;  2EF5 A;  1HQF A;  1P8M A;  2EF4 A;  4Q3V A;  3SKK A;  1ZPG A;  2A0M A;  1R1O A;  1T5F A;  4GSV A;  3CEV A;  1WVA A;  4HXQ A;  4Q3T A;  4RLA A;  4RHQ A;  1P8Q A;  4IU4 A;  3SL1 A;  3NIO A;  1HQ5 A;  4MXR A;  4RHM A;  1T4T A;  3GMZ A;  4MYF A;  1PQ3 A;  4MYN A;  1HQH A;  4RHL A;  3SJT A;  1WVB A;  3GN0 A;  2ZAV A;  3THJ A;  4Q42 A;  4IE1 A;  3E9B A;  1P8O A;  5CEV A;  3LHL A;  3THE A;  2PHA A;  4DZ4 A;  3M1R A;  3LP4 A;  1WOI A;  4I06 A;  1GQ7 A;  1T4R A;  3TH7 A;  3LP7 A;  3NIQ A;  4IU1 A;  3E8Z A;  1P8R A;  1T4S A;  1TBH A;  4Q3S A;  4MYK A;  1XFK A;  4FCK A;  3MJL A;  1TBL A;  4Q3R A;  1TBJ A;  2EIV A;  2PLL A;  1T5G A;  4G3H A;  1WOG A; 
#chains in the Genus database with same CATH topology
 1C3P A;  3KV2 A;  3MMR A;  1HQX A;  3MFW A;  4GSM A;  4HWW A;  4ITY A;  4HZE A;  4MYL A;  5EEF A;  4GWC A;  4Q40 A;  5G0X A;  3NIP A;  4ZUR A;  1P8P A;  5RLA A;  4FCI A;  1W22 A;  4BZ8 A;  5FUE A;  4IXU A;  2VQO A;  3C10 A;  4CEV A;  3DJ8 A;  5G1A A;  3E6K A;  4Q3U A;  4RHJ A;  5G17 A;  3MFV A;  3MZ3 A;  1T4P A;  4ZUQ A;  5EEI A;  1ZPE A;  4LY1 A;  3Q9E A;  3Q9B A;  1P8N A;  5DC7 A;  4IE2 A;  4ZUN A;  1CEV A;  3TF3 A;  3E6V A;  5G13 A;  3MAX A;  5HJ9 A;  3Q9F A;  4QA0 A;  5D1C A;  4CBT A;  4IU0 A;  2AEB A;  4RN0 A;  5LI3 A;  2CEV A;  1TA1 A;  4Q41 A;  5THS A;  4Q3Q A;  3F07 A;  1D3V A;  5ICN B;  4IE3 A;  4RHI A;  2VCG A;  5G1B A;  4BZ9 A;  3C0Z A;  5THT A;  4QA7 A;  3PZL A;  4Q3R C;  5IWG A;  5G0I A;  1ZZ0 A;  1WOH A;  3RLA A;  2PHO A;  4Q3P A;  3C0Y A;  4RHK A;  5D1B A;  1ZZ1 A;  3THH A;  1P8S A;  1HQG A;  1VKG A;  5EEK A;  4ZUO A;  4IU5 A;  5DC6 A;  5EFK B;  3SFH A;  4CBY A;  4QA6 A;  2V5X A;  3E8Q A;  4QA2 A;  5G0J A;  5IX0 A;  4CQF A;  3Q9C A;  2RLA A;  5G1C A;  1RLA A;  3SL0 A;  1GQ6 A;  3F06 A;  3F0R A;  3F80 A;  3ZNS A;  5HJA A;  4IXV A;  4QA3 A;  5BWZ A;  1T64 A;  4GSZ A;  2VQQ A;  4GWD A;  2EF5 A;  1HQF A;  1P8M A;  2EF4 A;  4Q3V A;  5EFJ D;  3SKK A;  3EWF A;  5D1D A;  1ZPG A;  2A0M A;  2VQW G;  3EW8 A;  3RQD A;  2V5W A;  5EF7 A;  3MEN A;  5EFN A;  2VQM A;  4QA5 A;  5EEM A;  4A69 A;  1R1O A;  1T5F A;  4GSV A;  3CEV A;  1WVA A;  4HXQ A;  4Q3T A;  4RLA A;  3EZT A;  4RHQ A;  5A2S A;  1P8Q A;  5G11 A;  2VQV A;  4IU4 A;  5G0G A;  4QA4 A;  3SL1 A;  3NIO A;  1HQ5 A;  4MXR A;  4RHM A;  1T4T A;  3GMZ A;  5G10 A;  3ZNR A;  1C3S A;  1T69 A;  4MYF A;  5EFB D;  4BZ5 A;  1PQ3 A;  3MZ6 A;  1HQH A;  4MYN A;  4RHL A;  3EZP A;  3SJT A;  1WVB A;  3GN0 A;  5FCW A;  5THV A;  2ZAV A;  3THJ A;  4Q42 A;  2VQJ A;  2GH6 A;  4IE1 A;  3E9B A;  1P8O A;  5G0H A;  4QA1 A;  5G0Y A;  5CEV A;  3LHL A;  1T67 A;  3THE A;  2PHA A;  4RN2 A;  3MZ4 A;  5DC5 A;  4DZ4 A;  3M1R A;  4LXZ A;  3LP4 A;  1WOI A;  4I06 A;  5EFH A;  5G12 A;  4BKX B;  4BZ6 A;  1GQ7 A;  1T4R A;  5EFG A;  3TH7 A;  5THU A;  3LP7 A;  3NIQ A;  4IU1 A;  4RN1 A;  5DC8 A;  5G3W A;  1ZZ3 A;  3E8Z A;  1C3R A;  4BZ7 A;  1P8R A;  5JI5 A;  1T4S A;  1TBH A;  4ZUP A;  4Q3S A;  5EF8 A;  4MYK A;  1XFK A;  4FCK A;  4ZUM A;  3MZ7 A;  3MJL A;  1TBL A;  4Q3R A;  1TBJ A;  2EIV A;  3SFF A;  5EEN A;  2PLL A;  1T5G A;  4G3H A;  1WOG A; 
#chains in the Genus database with same CATH homology
 3KV2 A;  3MMR A;  1HQX A;  3MFW A;  4GSM A;  4HWW A;  4ITY A;  4HZE A;  4MYL A;  4GWC A;  4Q40 A;  3NIP A;  1P8P A;  5RLA A;  4FCI A;  4IXU A;  4CEV A;  3DJ8 A;  3E6K A;  4Q3U A;  4RHJ A;  3MFV A;  1T4P A;  1ZPE A;  1P8N A;  4IE2 A;  1CEV A;  3TF3 A;  3E6V A;  5HJ9 A;  4IU0 A;  2AEB A;  2CEV A;  1TA1 A;  4Q41 A;  4Q3Q A;  1D3V A;  4IE3 A;  4RHI A;  3PZL A;  4Q3R C;  3RLA A;  1WOH A;  2PHO A;  4Q3P A;  4RHK A;  3THH A;  1P8S A;  1HQG A;  4IU5 A;  3E8Q A;  2RLA A;  1RLA A;  3SL0 A;  1GQ6 A;  5HJA A;  3F80 A;  4IXV A;  4GSZ A;  4GWD A;  2EF5 A;  1HQF A;  1P8M A;  2EF4 A;  4Q3V A;  3SKK A;  1ZPG A;  2A0M A;  1R1O A;  1T5F A;  4GSV A;  3CEV A;  1WVA A;  4HXQ A;  4Q3T A;  4RLA A;  4RHQ A;  1P8Q A;  4IU4 A;  3SL1 A;  3NIO A;  1HQ5 A;  4MXR A;  4RHM A;  1T4T A;  3GMZ A;  4MYF A;  1PQ3 A;  4MYN A;  1HQH A;  4RHL A;  3SJT A;  1WVB A;  3GN0 A;  2ZAV A;  3THJ A;  4Q42 A;  4IE1 A;  3E9B A;  1P8O A;  5CEV A;  3LHL A;  3THE A;  2PHA A;  4DZ4 A;  3M1R A;  3LP4 A;  1WOI A;  4I06 A;  1GQ7 A;  1T4R A;  3TH7 A;  3LP7 A;  3NIQ A;  4IU1 A;  3E8Z A;  1P8R A;  1T4S A;  1TBH A;  4Q3S A;  4MYK A;  1XFK A;  4FCK A;  3MJL A;  1TBL A;  4Q3R A;  1TBJ A;  2EIV A;  2PLL A;  1T5G A;  4G3H A;  1WOG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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