4EAFA

Thymidine phosphorylase from e.coli
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
440
structure length
440
Chain Sequence
LFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thymidine phosphorylase from E.coli
rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Thymidine phosphorylase
total genus 154
structure length 440
sequence length 440
ec nomenclature ec 2.4.2.4: Thymidine phosphorylase.
pdb deposition date 2012-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
A PF07831 PYNP_C Pyrimidine nucleoside phosphorylase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 4eafA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 4eafA02
3.90.1170.30 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Pyrimidine nucleoside phosphorylase-like, C-terminal domain 4eafA03
4OWOA 4YYYA 3GBRA 5BYTA 1KGZA 1GXBA 3TWPA 3QQSA 1UOUA 4X5DA 4ZTVA 4X5EA 4N5VA 5C2LA 2DSJA 1ZVWA 4OWMA 1OTPA 4IJ1A 4ZOKA 4N8QA 3UU1A 2GVQA 4OWSA 4X59A 4N93A 4X5CA 4YEKA 4EAFA 4OWNA 3QSAA 4X58A 4GIUA 5BO2A 1ZYKA 2J0FA 5C7SA 5EP8A 3R88A 2WK6A 1BRWA 4OWQA 3H5QA 4X46A 1ZXYA 4OWVA 5EY3A 3QR9A 4ZOFA 3QS8A 2ELCA 4GA6A 4ZOJA 4YI7A 4XR5A 4EADA 3R6CA 5BNEA 4GA5A 1V8GA 4GA4A 4GTNA 1KHDA 1O17A 4HKMA 5BO3A 1VQUA 2BPQA 4GKMA 2WK5A 5C1RA 1AZYA 4X5BA 4X5AA 4OWUA 4LHMA 4MUOA 2TPTA 4M0RA
chains in the Genus database with same CATH superfamily
1YJ9H 4OWOA 1ZXIB 4I9AA 2W54B 1FM0E 4IO9J 4YYYA 3C2RA 4US9A 3CMAH 1QAPA 3GBRA 4UY8M 5BYTA 3CCUH 1Q86J 1KGZA 1WKIA 1GXBA 1K8AJ 3TWPA 1VDVA 2OMDA 4KWWA 1RRZA 1FO4A 3QQSA 5MLCO 1N62B 2I14A 1VLBA 1UOUA 4X5DA 2ZJQJ 3CPWH 4ZTVA 3AM9A 4X5EA 3NRZC 4N5VA 3G4SH 2QEXH 1JROB 5C2LA 2DSJA 1QPOA 1ZVWA 4OWMA 4C7YA 4WCEJ 3CCQH 4USAA 2OTJH 1KD1J 1OTPA 1N60B 3RPFA 3PIPJ 5GADN 3SR6C 4IJ1A 4ZOKA 1VQ6H 1WYGA 4N8QA 5HL7J 1QPQA 3UU1A 2W3RB 2OTLH 3CC2H 5AYYA 1QPRA 1KQSH 2GVQA 4OWSA 4X59A 1JJ2H 3G71H 4N93A 2ZJPJ 1N63B 5HULA 1FFUB 2Q5WE 1VQNH 3CF5J 3CCSH 2WP4A 4X5CA 4YEKA 3CCLH 3NVWC 3C2OA 4WFNJ 4EAFA 1SB3A 1X1OA 4OWNA 3C2EA 1NJIJ 5AYZA 3QSAA 4X58A 1VQ5H 2B7NA 1W2BH 4GIUA 1K73J 1RF8B 4ZOHA 5JVHJ 3PAJA 1M90J 1VQ9H 3BIIE 2E3TA 1YITH 1V97A 2I1OA 3DLLJ 1YHQH 4C7ZA 5BO2A 1ZYKA 2ZJRJ 3VMMA 1DGJA 2J0FA 5C7SA 5MPOC 5EP8A 1YTDA 3R88A 2WK6A 1N5XA 1YTKA 3G6EH 3CXCH 3CC4H 1BRWA 5GAHN 1Y69K 4OWQA 1VQ8H 3WNZA 3CC7H 1KC8J 3H5QA 4X46A 5DM6J 3NS1C 4C80A 1M1KJ 1S72H 1ZXYA 4OWVA 1QPNA 3L4PA 5EY3A 3QR9A 4AP8A 5H1SO 1YJWH 1Q82J 1QVGH 1JRPB 3CD6H 1FMAE 3CCEH 1N8RJ 1VQMH 3C2VA 4ZOFA 1N5WB 2B7QA 3QS8A 2PA2A 3CCVH 1NVJA 1YJNH 3CCJH 1O4UA 4WF9J 2ELCA 3B9JC 4GA6A 4ZOJA 2QIEA 3C2FA 3NVZC 2W55B 3AMZA 3ETRC 4YI7A 4XR5A 4EADA 3R6CA 5BNEA 3AN1A 3WO0A 4GA5A 1V8GA 3NVVC 1Q81J 4GA4A 4WFAJ 1VQOH 1YTEA 1VQKH 2B7PA 4GTNA 3TQVA 1KHDA 1O17A 3OW2H 4HKMA 1FIQC 1FFVB 1RM6A 1VQPH 5BO3A 3I55H 2JBMA 2W3SB 1VQUA 2BPQA 3WO1A 3PIOJ 1K9MJ 1Q7YJ 5HUPA 5AN9F 3EUB4 1YI2H 4WFBJ 3GNNA 1NVIE 4GKMA 5HUOA 4KWVA 4US8A 2WK5A 5C1RA 3FC4A 1AZYA 1N61B 4X5BA 5GAEN 3I56H 3CCMH 1VQ7H 3CMEH 4F3FC 3J7ZM 1QVFH 4IOAJ 5DM7J 3CCRH 4X5AA 1SIJA 3NVYC 1YIJH 1VQLH 4U67J 3FAHA 4IOCJ 4OWUA 3L0GA 5GAGN 2QA4H 5JVGJ 5AYXA 4LHMA 4MUOA 1VQ4H 2TPTA 4M0RA
chains in the Genus database with same CATH topology
4OWOA 4YYYA 3GBRA 5BYTA 1KGZA 1GXBA 3TWPA 3QQSA 1UOUA 4X5DA 4ZTVA 4X5EA 4N5VA 5C2LA 2DSJA 1ZVWA 4OWMA 1OTPA 4IJ1A 4ZOKA 4N8QA 3UU1A 2GVQA 4OWSA 4X59A 4N93A 4X5CA 4YEKA 4EAFA 4OWNA 3QSAA 4X58A 4GIUA 5BO2A 1ZYKA 2J0FA 5C7SA 5EP8A 3R88A 2WK6A 1BRWA 4OWQA 3H5QA 4X46A 1ZXYA 4OWVA 5EY3A 3QR9A 4ZOFA 3QS8A 2ELCA 4GA6A 4ZOJA 4YI7A 4XR5A 4EADA 3R6CA 5BNEA 4GA5A 1V8GA 4GA4A 4GTNA 1KHDA 1O17A 4HKMA 5BO3A 1VQUA 2BPQA 4GKMA 2WK5A 5C1RA 1AZYA 4X5BA 4X5AA 4OWUA 4LHMA 4MUOA 2TPTA 4M0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OWO A;  4YYY A;  3GBR A;  5BYT A;  1KGZ A;  1GXB A;  3TWP A;  3QQS A;  1UOU A;  4X5D A;  4ZTV A;  4X5E A;  4N5V A;  5C2L A;  2DSJ A;  1ZVW A;  4OWM A;  1OTP A;  4IJ1 A;  4ZOK A;  4N8Q A;  3UU1 A;  2GVQ A;  4OWS A;  4X59 A;  4N93 A;  4X5C A;  4YEK A;  4EAF A;  4OWN A;  3QSA A;  4X58 A;  4GIU A;  5BO2 A;  1ZYK A;  2J0F A;  5C7S A;  5EP8 A;  3R88 A;  2WK6 A;  1BRW A;  4OWQ A;  3H5Q A;  4X46 A;  1ZXY A;  4OWV A;  5EY3 A;  3QR9 A;  4ZOF A;  3QS8 A;  2ELC A;  4GA6 A;  4ZOJ A;  4YI7 A;  4XR5 A;  4EAD A;  3R6C A;  5BNE A;  4GA5 A;  1V8G A;  4GA4 A;  4GTN A;  1KHD A;  1O17 A;  4HKM A;  5BO3 A;  1VQU A;  2BPQ A;  4GKM A;  2WK5 A;  5C1R A;  1AZY A;  4X5B A;  4X5A A;  4OWU A;  4LHM A;  4MUO A;  2TPT A;  4M0R A; 
#chains in the Genus database with same CATH topology
 1YJ9 H;  4OWO A;  1ZXI B;  4I9A A;  2W54 B;  1FM0 E;  4IO9 J;  4YYY A;  3C2R A;  4US9 A;  3CMA H;  1QAP A;  3GBR A;  4UY8 M;  5BYT A;  3CCU H;  1Q86 J;  1KGZ A;  1WKI A;  1GXB A;  1K8A J;  3TWP A;  1VDV A;  2OMD A;  4KWW A;  1RRZ A;  1FO4 A;  3QQS A;  5MLC O;  1N62 B;  2I14 A;  1VLB A;  1UOU A;  4X5D A;  2ZJQ J;  3CPW H;  4ZTV A;  3AM9 A;  4X5E A;  3NRZ C;  4N5V A;  3G4S H;  2QEX H;  1JRO B;  5C2L A;  2DSJ A;  1QPO A;  1ZVW A;  4OWM A;  4C7Y A;  4WCE J;  3CCQ H;  4USA A;  2OTJ H;  1KD1 J;  1OTP A;  1N60 B;  3RPF A;  3PIP J;  5GAD N;  3SR6 C;  4IJ1 A;  4ZOK A;  1VQ6 H;  1WYG A;  4N8Q A;  5HL7 J;  1QPQ A;  3UU1 A;  2W3R B;  2OTL H;  3CC2 H;  5AYY A;  1QPR A;  1KQS H;  2GVQ A;  4OWS A;  4X59 A;  1JJ2 H;  3G71 H;  4N93 A;  2ZJP J;  1N63 B;  5HUL A;  1FFU B;  2Q5W E;  1VQN H;  3CF5 J;  3CCS H;  2WP4 A;  4X5C A;  4YEK A;  3CCL H;  3NVW C;  3C2O A;  4WFN J;  4EAF A;  1SB3 A;  1X1O A;  4OWN A;  3C2E A;  1NJI J;  5AYZ A;  3QSA A;  4X58 A;  1VQ5 H;  2B7N A;  1W2B H;  4GIU A;  1K73 J;  1RF8 B;  4ZOH A;  5JVH J;  3PAJ A;  1M90 J;  1VQ9 H;  3BII E;  2E3T A;  1YIT H;  1V97 A;  2I1O A;  3DLL J;  1YHQ H;  4C7Z A;  5BO2 A;  1ZYK A;  2ZJR J;  3VMM A;  1DGJ A;  2J0F A;  5C7S A;  5MPO C;  5EP8 A;  1YTD A;  3R88 A;  2WK6 A;  1N5X A;  1YTK A;  3G6E H;  3CXC H;  3CC4 H;  1BRW A;  5GAH N;  1Y69 K;  4OWQ A;  1VQ8 H;  3WNZ A;  3CC7 H;  1KC8 J;  3H5Q A;  4X46 A;  5DM6 J;  3NS1 C;  4C80 A;  1M1K J;  1S72 H;  1ZXY A;  4OWV A;  1QPN A;  3L4P A;  5EY3 A;  3QR9 A;  4AP8 A;  5H1S O;  1YJW H;  1Q82 J;  1QVG H;  1JRP B;  3CD6 H;  1FMA E;  3CCE H;  1N8R J;  1VQM H;  3C2V A;  4ZOF A;  1N5W B;  2B7Q A;  3QS8 A;  2PA2 A;  3CCV H;  1NVJ A;  1YJN H;  3CCJ H;  1O4U A;  4WF9 J;  2ELC A;  3B9J C;  4GA6 A;  4ZOJ A;  2QIE A;  3C2F A;  3NVZ C;  2W55 B;  3AMZ A;  3ETR C;  4YI7 A;  4XR5 A;  4EAD A;  3R6C A;  5BNE A;  3AN1 A;  3WO0 A;  4GA5 A;  1V8G A;  3NVV C;  1Q81 J;  4GA4 A;  4WFA J;  1VQO H;  1YTE A;  1VQK H;  2B7P A;  4GTN A;  3TQV A;  1KHD A;  1O17 A;  3OW2 H;  4HKM A;  1FIQ C;  1FFV B;  1RM6 A;  1VQP H;  5BO3 A;  3I55 H;  2JBM A;  2W3S B;  1VQU A;  2BPQ A;  3WO1 A;  3PIO J;  1K9M J;  1Q7Y J;  5HUP A;  5AN9 F;  3EUB 4;  1YI2 H;  4WFB J;  3GNN A;  1NVI E;  4GKM A;  5HUO A;  4KWV A;  4US8 A;  2WK5 A;  5C1R A;  3FC4 A;  1AZY A;  1N61 B;  4X5B A;  5GAE N;  3I56 H;  3CCM H;  1VQ7 H;  3CME H;  4F3F C;  3J7Z M;  1QVF H;  4IOA J;  5DM7 J;  3CCR H;  4X5A A;  1SIJ A;  3NVY C;  1YIJ H;  1VQL H;  4U67 J;  3FAH A;  4IOC J;  4OWU A;  3L0G A;  5GAG N;  2QA4 H;  5JVG J;  5AYX A;  4LHM A;  4MUO A;  1VQ4 H;  2TPT A;  4M0R A; 
#chains in the Genus database with same CATH homology
 4OWO A;  4YYY A;  3GBR A;  5BYT A;  1KGZ A;  1GXB A;  3TWP A;  3QQS A;  1UOU A;  4X5D A;  4ZTV A;  4X5E A;  4N5V A;  5C2L A;  2DSJ A;  1ZVW A;  4OWM A;  1OTP A;  4IJ1 A;  4ZOK A;  4N8Q A;  3UU1 A;  2GVQ A;  4OWS A;  4X59 A;  4N93 A;  4X5C A;  4YEK A;  4EAF A;  4OWN A;  3QSA A;  4X58 A;  4GIU A;  5BO2 A;  1ZYK A;  2J0F A;  5C7S A;  5EP8 A;  3R88 A;  2WK6 A;  1BRW A;  4OWQ A;  3H5Q A;  4X46 A;  1ZXY A;  4OWV A;  5EY3 A;  3QR9 A;  4ZOF A;  3QS8 A;  2ELC A;  4GA6 A;  4ZOJ A;  4YI7 A;  4XR5 A;  4EAD A;  3R6C A;  5BNE A;  4GA5 A;  1V8G A;  4GA4 A;  4GTN A;  1KHD A;  1O17 A;  4HKM A;  5BO3 A;  1VQU A;  2BPQ A;  4GKM A;  2WK5 A;  5C1R A;  1AZY A;  4X5B A;  4X5A A;  4OWU A;  4LHM A;  4MUO A;  2TPT A;  4M0R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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