4EAFA

Thymidine phosphorylase from e.coli
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
440
structure length
440
Chain Sequence
LFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thymidine phosphorylase from E.coli
rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Thymidine phosphorylase
total genus 154
structure length 440
sequence length 440
ec nomenclature ec 2.4.2.4: Thymidine phosphorylase.
pdb deposition date 2012-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
A PF07831 PYNP_C Pyrimidine nucleoside phosphorylase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 4eafA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 4eafA02
3.90.1170.30 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Pyrimidine nucleoside phosphorylase-like, C-terminal domain 4eafA03
2BPQA 4ZOFA 4N5VA 4MUOA 1VQUA 3QS8A 4GIUA 4OWQA 1ZXYA 5C2LA 1KGZA 4LHMA 1GXBA 2GVQA 4N8QA 4ZOJA 4GA6A 1ZYKA 4X59A 4GTNA 1O17A 1OTPA 4N93A 3QSAA 3R88A 2TPTA 5C7SA 4X5AA 4X5DA 2WK5A 3QQSA 5C1RA 4OWOA 4OWMA 2ELCA 5EY3A 4IJ1A 4XR5A 1AZYA 3R6CA 4YI7A 4ZOKA 2J0FA 4GA5A 5BNEA 5EP8A 4ZTVA 4X5EA 3QR9A 4GKMA 1BRWA 4YEKA 4OWNA 4X5BA 4OWUA 4GA4A 4M0RA 5BO2A 1KHDA 4X58A 3GBRA 4OWVA 4YYYA 5BO3A 4X5CA 3TWPA 3H5QA 4EAFA 5BYTA 1UOUA 4OWSA 1ZVWA 2DSJA 1V8GA 4X46A 2WK6A 4HKMA 3UU1A 4EADA
chains in the Genus database with same CATH superfamily
4USAA 2OMDA 2JBMA 1VQKH 2BPQA 3CC4H 4ZOFA 3CCMH 1JJ2H 2B7QA 5GAEN 2I14A 5MPOC 4N5VA 1NJIJ 3CC2H 4I9AA 3NVWC 1YJWH 4WFNJ 4IOCJ 1Y69K 1Q82J 4MUOA 1M90J 1VQUA 2I1OA 2Q5WE 5GAGN 1FMAE 1FIQC 3AM9A 1JRPB 3QS8A 3SR6C 3VMMA 5DM6J 4GIUA 1VQMH 4OWQA 2W3RB 1VQ8H 3BIIE 2E3TA 1ZXYA 3NRZC 4AP8A 5HUPA 5C2LA 1KGZA 4LHMA 3G6EH 4WCEJ 1SB3A 5AYXA 5GADN 1GXBA 2GVQA 4N8QA 1N61B 4ZOJA 3C2VA 1VLBA 1VQ5H 1VQ7H 5AYZA 2W54B 1FM0E 1S72H 4GA6A 1ZYKA 4X59A 1N63B 2WP4A 3CXCH 4GTNA 3NVYC 1VQ6H 1YTDA 3PIPJ 1O17A 1OTPA 4N93A 3QSAA 3R88A 1DGJA 2TPTA 1SIJA 1X1OA 5AN9F 5MLCO 4U67J 5C7SA 1WKIA 1K8AJ 3CCVH 2OTLH 1N5XA 4X5AA 1N62B 3C2FA 5AYYA 5DM7J 4WFBJ 4F3FC 3AMZA 3C2OA 4X5DA 4IOAJ 2WK5A 2B7PA 1KQSH 3QQSA 1K73J 1FFUB 1QPOA 2ZJPJ 5C1RA 3G4SH 1YJ9H 4OWOA 1K9MJ 2B7NA 4OWMA 2ELCA 5EY3A 1N8RJ 4US9A 3CPWH 3WO0A 2QA4H 3CCLH 4UY8M 4IJ1A 3B9JC 4XR5A 3WO1A 3TQVA 1AZYA 1W2BH 3CCQH 5H1SO 3R6CA 1QVFH 4YI7A 3I56H 4ZOKA 1QAPA 1YI2H 1VQ9H 1VQNH 2J0FA 4GA5A 3ETRC 1ZXIB 5HULA 5HUOA 1QPRA 5BNEA 4KWWA 3CMAH 3CCUH 1YITH 1QVGH 5EP8A 4ZTVA 1N60B 1YTEA 4X5EA 4WF9J 2ZJQJ 3CF5J 3WNZA 3QR9A 1Q81J 3DLLJ 4GKMA 4C7YA 1VQPH 1M1KJ 1VQLH 3G71H 1BRWA 1Q86J 4YEKA 1N5WB 4OWNA 3J7ZM 3CCSH 3CD6H 4X5BA 3GNNA 4OWUA 1Q7YJ 4GA4A 3CCJH 1RF8B 4M0RA 3FAHA 4WFAJ 3CCRH 1KC8J 1O4UA 4C7ZA 1VQOH 1VDVA 1FO4A 1V97A 3CC7H 5BO2A 3PIOJ 1KHDA 4X58A 3NVZC 3GBRA 3NVVC 1FFVB 1JROB 4OWVA 3L0GA 1WYGA 4YYYA 1YHQH 2OTJH 2W55B 5BO3A 4X5CA 1QPNA 3C2RA 3AN1A 1YIJH 3TWPA 4ZOHA 5JVHJ 3OW2H 3H5QA 4EAFA 3CMEH 2QEXH 1YTKA 1RM6A 3EUB4 5BYTA 1UOUA 2PA2A 4OWSA 1ZVWA 3I55H 5JVGJ 2W3SB 4KWVA 2DSJA 3C2EA 5GAHN 1YJNH 1VQ4H 3L4PA 4US8A 4C80A 1KD1J 1NVIE 5HL7J 1V8GA 4X46A 3NS1C 2WK6A 3CCEH 3FC4A 3PAJA 1RRZA 1NVJA 4HKMA 3UU1A 1QPQA 4IO9J 4EADA 2ZJRJ 3RPFA 2QIEA
chains in the Genus database with same CATH topology
2BPQA 4ZOFA 4N5VA 4MUOA 1VQUA 3QS8A 4GIUA 4OWQA 1ZXYA 5C2LA 1KGZA 4LHMA 1GXBA 2GVQA 4N8QA 4ZOJA 4GA6A 1ZYKA 4X59A 4GTNA 1O17A 1OTPA 4N93A 3QSAA 3R88A 2TPTA 5C7SA 4X5AA 4X5DA 2WK5A 3QQSA 5C1RA 4OWOA 4OWMA 2ELCA 5EY3A 4IJ1A 4XR5A 1AZYA 3R6CA 4YI7A 4ZOKA 2J0FA 4GA5A 5BNEA 5EP8A 4ZTVA 4X5EA 3QR9A 4GKMA 1BRWA 4YEKA 4OWNA 4X5BA 4OWUA 4GA4A 4M0RA 5BO2A 1KHDA 4X58A 3GBRA 4OWVA 4YYYA 5BO3A 4X5CA 3TWPA 3H5QA 4EAFA 5BYTA 1UOUA 4OWSA 1ZVWA 2DSJA 1V8GA 4X46A 2WK6A 4HKMA 3UU1A 4EADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BPQ A;  4ZOF A;  4N5V A;  4MUO A;  1VQU A;  3QS8 A;  4GIU A;  4OWQ A;  1ZXY A;  5C2L A;  1KGZ A;  4LHM A;  1GXB A;  2GVQ A;  4N8Q A;  4ZOJ A;  4GA6 A;  1ZYK A;  4X59 A;  4GTN A;  1O17 A;  1OTP A;  4N93 A;  3QSA A;  3R88 A;  2TPT A;  5C7S A;  4X5A A;  4X5D A;  2WK5 A;  3QQS A;  5C1R A;  4OWO A;  4OWM A;  2ELC A;  5EY3 A;  4IJ1 A;  4XR5 A;  1AZY A;  3R6C A;  4YI7 A;  4ZOK A;  2J0F A;  4GA5 A;  5BNE A;  5EP8 A;  4ZTV A;  4X5E A;  3QR9 A;  4GKM A;  1BRW A;  4YEK A;  4OWN A;  4X5B A;  4OWU A;  4GA4 A;  4M0R A;  5BO2 A;  1KHD A;  4X58 A;  3GBR A;  4OWV A;  4YYY A;  5BO3 A;  4X5C A;  3TWP A;  3H5Q A;  4EAF A;  5BYT A;  1UOU A;  4OWS A;  1ZVW A;  2DSJ A;  1V8G A;  4X46 A;  2WK6 A;  4HKM A;  3UU1 A;  4EAD A; 
#chains in the Genus database with same CATH topology
 4USA A;  2OMD A;  2JBM A;  1VQK H;  2BPQ A;  3CC4 H;  4ZOF A;  3CCM H;  1JJ2 H;  2B7Q A;  5GAE N;  2I14 A;  5MPO C;  4N5V A;  1NJI J;  3CC2 H;  4I9A A;  3NVW C;  1YJW H;  4WFN J;  4IOC J;  1Y69 K;  1Q82 J;  4MUO A;  1M90 J;  1VQU A;  2I1O A;  2Q5W E;  5GAG N;  1FMA E;  1FIQ C;  3AM9 A;  1JRP B;  3QS8 A;  3SR6 C;  3VMM A;  5DM6 J;  4GIU A;  1VQM H;  4OWQ A;  2W3R B;  1VQ8 H;  3BII E;  2E3T A;  1ZXY A;  3NRZ C;  4AP8 A;  5HUP A;  5C2L A;  1KGZ A;  4LHM A;  3G6E H;  4WCE J;  1SB3 A;  5AYX A;  5GAD N;  1GXB A;  2GVQ A;  4N8Q A;  1N61 B;  4ZOJ A;  3C2V A;  1VLB A;  1VQ5 H;  1VQ7 H;  5AYZ A;  2W54 B;  1FM0 E;  1S72 H;  4GA6 A;  1ZYK A;  4X59 A;  1N63 B;  2WP4 A;  3CXC H;  4GTN A;  3NVY C;  1VQ6 H;  1YTD A;  3PIP J;  1O17 A;  1OTP A;  4N93 A;  3QSA A;  3R88 A;  1DGJ A;  2TPT A;  1SIJ A;  1X1O A;  5AN9 F;  5MLC O;  4U67 J;  5C7S A;  1WKI A;  1K8A J;  3CCV H;  2OTL H;  1N5X A;  4X5A A;  1N62 B;  3C2F A;  5AYY A;  5DM7 J;  4WFB J;  4F3F C;  3AMZ A;  3C2O A;  4X5D A;  4IOA J;  2WK5 A;  2B7P A;  1KQS H;  3QQS A;  1K73 J;  1FFU B;  1QPO A;  2ZJP J;  5C1R A;  3G4S H;  1YJ9 H;  4OWO A;  1K9M J;  2B7N A;  4OWM A;  2ELC A;  5EY3 A;  1N8R J;  4US9 A;  3CPW H;  3WO0 A;  2QA4 H;  3CCL H;  4UY8 M;  4IJ1 A;  3B9J C;  4XR5 A;  3WO1 A;  3TQV A;  1AZY A;  1W2B H;  3CCQ H;  5H1S O;  3R6C A;  1QVF H;  4YI7 A;  3I56 H;  4ZOK A;  1QAP A;  1YI2 H;  1VQ9 H;  1VQN H;  2J0F A;  4GA5 A;  3ETR C;  1ZXI B;  5HUL A;  5HUO A;  1QPR A;  5BNE A;  4KWW A;  3CMA H;  3CCU H;  1YIT H;  1QVG H;  5EP8 A;  4ZTV A;  1N60 B;  1YTE A;  4X5E A;  4WF9 J;  2ZJQ J;  3CF5 J;  3WNZ A;  3QR9 A;  1Q81 J;  3DLL J;  4GKM A;  4C7Y A;  1VQP H;  1M1K J;  1VQL H;  3G71 H;  1BRW A;  1Q86 J;  4YEK A;  1N5W B;  4OWN A;  3J7Z M;  3CCS H;  3CD6 H;  4X5B A;  3GNN A;  4OWU A;  1Q7Y J;  4GA4 A;  3CCJ H;  1RF8 B;  4M0R A;  3FAH A;  4WFA J;  3CCR H;  1KC8 J;  1O4U A;  4C7Z A;  1VQO H;  1VDV A;  1FO4 A;  1V97 A;  3CC7 H;  5BO2 A;  3PIO J;  1KHD A;  4X58 A;  3NVZ C;  3GBR A;  3NVV C;  1FFV B;  1JRO B;  4OWV A;  3L0G A;  1WYG A;  4YYY A;  1YHQ H;  2OTJ H;  2W55 B;  5BO3 A;  4X5C A;  1QPN A;  3C2R A;  3AN1 A;  1YIJ H;  3TWP A;  4ZOH A;  5JVH J;  3OW2 H;  3H5Q A;  4EAF A;  3CME H;  2QEX H;  1YTK A;  1RM6 A;  3EUB 4;  5BYT A;  1UOU A;  2PA2 A;  4OWS A;  1ZVW A;  3I55 H;  5JVG J;  2W3S B;  4KWV A;  2DSJ A;  3C2E A;  5GAH N;  1YJN H;  1VQ4 H;  3L4P A;  4US8 A;  4C80 A;  1KD1 J;  1NVI E;  5HL7 J;  1V8G A;  4X46 A;  3NS1 C;  2WK6 A;  3CCE H;  3FC4 A;  3PAJ A;  1RRZ A;  1NVJ A;  4HKM A;  3UU1 A;  1QPQ A;  4IO9 J;  4EAD A;  2ZJR J;  3RPF A;  2QIE A; 
#chains in the Genus database with same CATH homology
 2BPQ A;  4ZOF A;  4N5V A;  4MUO A;  1VQU A;  3QS8 A;  4GIU A;  4OWQ A;  1ZXY A;  5C2L A;  1KGZ A;  4LHM A;  1GXB A;  2GVQ A;  4N8Q A;  4ZOJ A;  4GA6 A;  1ZYK A;  4X59 A;  4GTN A;  1O17 A;  1OTP A;  4N93 A;  3QSA A;  3R88 A;  2TPT A;  5C7S A;  4X5A A;  4X5D A;  2WK5 A;  3QQS A;  5C1R A;  4OWO A;  4OWM A;  2ELC A;  5EY3 A;  4IJ1 A;  4XR5 A;  1AZY A;  3R6C A;  4YI7 A;  4ZOK A;  2J0F A;  4GA5 A;  5BNE A;  5EP8 A;  4ZTV A;  4X5E A;  3QR9 A;  4GKM A;  1BRW A;  4YEK A;  4OWN A;  4X5B A;  4OWU A;  4GA4 A;  4M0R A;  5BO2 A;  1KHD A;  4X58 A;  3GBR A;  4OWV A;  4YYY A;  5BO3 A;  4X5C A;  3TWP A;  3H5Q A;  4EAF A;  5BYT A;  1UOU A;  4OWS A;  1ZVW A;  2DSJ A;  1V8G A;  4X46 A;  2WK6 A;  4HKM A;  3UU1 A;  4EAD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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