4GU4A

Crystal structure of the t1l reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
205
structure length
205
Chain Sequence
KIDSVLPPLTVREASGVRTLSFGYDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVADRFGMRTGTWTGQLQYQHPQLSWRANVTLNLMKVDDWLVLSFSQMTTNSIMADGKFVINFVSGLSSGWQTGDTEPSSTIDPLSTTFAAVQFLNNGQRIDAFRIMGVSEWTDGELEIKNYGGTYTGHTQVYWAPWTIMYPCNV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus.
pubmed doi rcsb
molecule tags Viral protein
source organism Mammalian orthoreovirus 1
molecule keywords Outer capsid protein sigma-1
total genus 30
structure length 205
sequence length 205
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.20 Mainly Beta Ribbon Laminin reovirus attachment protein sigma1; domain 1 4gu4A01
2.60.90.20 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Virus attachment protein , globular domain 4gu4A02
1KKEA 4GU3A 1V1HA 4GU4A 2OJ6A 3EOYA 1QIUA 2VRSA 4ODBA 2JJLA 4XC5A 5MHSA 1V1IA 2BSFA 3S6XA 2BT8A 2BT7A 2OJ5A
chains in the Genus database with same CATH superfamily
3TK5B 2BOHA 3HO3A 3CENL 2W2NE 1OB1C 4BDWA 1MQ5L 4ATZA 3KQCL 2VWNL 3N8YA 2BOXA 4BTTA 2JKHL 1HX2A 1BF9A 1YUFA 4COXA 1GK5A 2W3IB 1ADXA 2ADXA 2KV4A 4RRXA 4D62A 4Y6DB 2W2PE 2Y7XB 1FE2A 3SOVA 5K0HB 3R05A 1CVUA 1QHVA 1F7MA 4ISIL 1IQFL 4TGFA 1ZAQA 2HORA 1U8CB 4X8UL 4G1MB 1FAKL 1G1SA 1H7ZA 1N1IA 1WHEA 1NT0A 3U7UG 5I46L 3IITB 3LTFB 5E8DA 2G00L 1EMNA 2J4IB 4CW8A 1KLOA 3PGHA 2WGUA 1P69A 5IKTA 2P16L 1Z6EL 2XBVL 1HJ7A 1C5MF 4D63A 1Q4GA 4JZEL 4M10A 5JB9E 1DDXA 2WBWA 2YGPA 2BZUA 3KQBL 1LPZA 4XBMA 1KIGL 5JBAE 2KNIA 1CVWL 2Y5FL 2BQ6A 1V3XB 1EGFA 1KACA 1LMJA 4O1ZA 3O8EA 4XL1A 3ENSA 2J38B 3GCXE 3GISX 4RUTA 4Z0LA 2Q1JB 1NFWB 5JBBE 1P0SL 3HS6A 4GU4A 3V64C 1WU1B 2WPKE 2W2OE 4D0FA 2QLKA 4K6VA 2VVCK 4Z0KB 1YUGA 3MQEA 2H9EL 4C16A 2UWOB 1ATAA 3MDLA 1UXEA 5JVZA 1J9CL 2MHPA 2P3FN 1HAFA 4JYVL 2VH6B 1YUKB 1F7EA 2PUQL 1NFUB 4CUDA 1COUA 4XQBA 1IOXA 4AQTA 1G1TA 3N8YB 3SW2A 1I0UA 2YGQA 2MGRA 1PXXA 3NTBA 4BDXA 1DX5I 2EI7B 1HREA 2W86A 1M1XB 3TH3L 1TOZA 2IUMA 1HT8A 3EXVA 3N8XA 4Z6AL 2J34B 4JZDL 1APOA 3TGFA 1K37A 2KL7A 2OYUP 3TBDA 4BXSA 4PH9A 4D90A 1APQA 3POYA 1FSBA 2BQ7A 1IQLL 4BTIA 1P6AA 1EZQB 2WPME 1UXAA 2VVVL 2P3UA 2PR3B 1FFMA 2YGOA 3ZYJB 1DVAL 5F19A 1CQEA 1IQGL 1NZIA 4ZDGA 2BZ6L 3M37L 1W7XL 3FBYA 1EPGA 2P93L 2VWMK 3CS7L 3LAQA 4MMXB 2J95B 1IQEL 1TPGA 4FM5A 4CUEA 1JBUL 1MQ6L 2EI8B 1QIUA 1KSNB 1N7DA 1YO8A 1QFKL 2WZPP 4ZHAB 2XBXL 6COXA 1ATEA 3N8WA 3M36L 1LPGA 2GD4A 2I9BA 3NT1A 3F6UL 3QCWA 5CKQA 2W26B 3U73A 1G1RA 1EBVA 3P5BL 1XKBA 5CKMA 4MMYB 2OJ6A 2B7DL 5IKVA 3KQEL 4XL8A 3OLUA 2K2SB 4ZAEB 3ELAL 4BXWA 2VWLL 2RHPA 4ZXYL 1XDTR 2W2QE 2BT7A 3KCGL 4RS0A 5F1AA 2H9EC 1CX2A 1UZQA 2P94L 4ODBA 2VTWA 2MGPA 4WYJA 1IQIL 3GCWE 2M74A 1RFNB 2FLRL 2RNLA 1MOXC 3LC5B 1KNBA 3N0IA 1WHFA 3LN1A 1IP0A 4LIYA 1IQHL 1LPKA 4YT7L 1B9WA 4OTYA 2WYJB 3BQ4A 3N8VA 3EGFA 1IQKL 1LK9A 3BT1A 2P26A 2NPRA 2BO2A 3BT2A 2Y80B 2XBWL 3LN0A 3ZPEA 3QMOA 4X8SL 2WYGB 3ZYGA 1IQML 2Y81B 3K9XA 1IJQA 1FJSL 3ZPFA 2UWLB 3ASIA 1DIYA 2RA0L 1PTHA 1CCFA 4YT6L 1KLJL 2J1KC 2Y38A 2TGFA 3Q7DA 2BT8A 1HT5A 2VH0B 5MHSA 4NGAL 3S6XA 3ZYIB 2WGTA 1X7AL 1TLEA 2XC4L 4K6UA 2WBVA 2WG4B 1HAEA 1O5DL 2BMGA 2P3TA 2KB9A 2WG3C 3C9AC 4OTJA 1EPIA 2UWPB 1L5GB 2XC5L 1XKAL 3BPSE 2WPIE 5JB8E 1NQLB 3TK6B 2WSTA 1UZKA 1CCVA 2BZVA 2P28B 1JV2B 2EI6B 4JZFL 3H5CB 1W8BL 4GU3A 3IJEB 5JW1A 4YZUB 3LIWB 2VJ3A 4RRZA 4MMZB 3KK6A 5IKRA 1UZPA 1EPJA 2HOXA 4ZH8B 2BQWA 3DEMA 3RR3A 2XC0L 4CUFA 3F1SB 4RRYA 4RRWA 3LC3B 4LMFA 1HRFA 3OLTA 4XC5A 3L89A 1EPHA 3NJPC 1U67A 4X8VL 1K36A 3LTGD 2J12A 1G1QA 2OJ5A 2I9AA 2W3KB 1IVOC 1ATBA 5CKNA 2PHBB 2AYLA 4LORA 2WFTA 4ISHL 2IUNA 1IQJL 1LMMA 1PFXL 3EOYA 3SOQA 3CA7A 2Y82B 2VWOL 1NOBA 3HS5A 5JVYA 1EAIC 5L2YL 1KKEA 2FD6A 2P3FL 3KRKA 2J2JA 5EGMB 1SZBA 4Y7AB 1NFXB 5L30L 1IGXA 3HPTA 1IQNL 1Z6CA 2W9LC 5CISA 3HS7A 5L2ZL 1UXBA 1JL9A 1HZ8A 3F0YA 3EXWA 1ATDA 1EQGA 1UZJA 1V1HA 1LQDA 2WPLE 4NG9L 2Y5GL 3CNCA 1HCGB 1FAXL 3FFGL 1PGEA 2BOKL 2FLBL 1FF7A 4A7IA 1DQBA 5JBCE 2WPHE 5COXA 1AUTL 2J94B 1IOEL 2D1JB 2FLGA 2VRSA 1F0SB 2VVUL 3HO5A 3NTGA 2O39A 1NPEB 2JJLA 1V1IA 3Q3KB 2DDUA 2XBYL 4Y79B 2CJIB 2Y7ZB 4ZXXL 3SOBB 3HO4A 4O02B 1G2LB 1NFYB 1YGCL 1EMOA 4M11A 4D0EA 5KN5C 4BTUA 1P9JA 2J2UB 2BOUA 4K6WA 3L88A 1L3YA 1G2MB 3FCSB 1CEJA 3N8ZA 4XQAA 2W2ME 3V65B 2WPJE 1F0RB 2OYEP 2P95L 4NA9L 5KIRA 1IGZA 4Y76B 4Y7BB 3CFWA 2BSFA 1URKA 3KQDL 3TZIA 5IKQA 4E1GA 2FZZL 4X8TL 3N8WB 3KL6B 1A3PA 3QH0A 4A94C 2F9BL 4CSYA 1EQHA 2K2TA 4XLWA 2Y5HL 4JYUL 1XFEA 4Y71B 5FDQA 3QNDA 4K6TA 1PRHA 2WFXB 1KLIL
chains in the Genus database with same CATH topology
1KKEA 4GU3A 1V1HA 4GU4A 2OJ6A 3EOYA 1QIUA 2VRSA 4ODBA 2JJLA 4XC5A 5MHSA 1V1IA 2BSFA 3S6XA 2BT8A 2BT7A 2OJ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KKE A;  4GU3 A;  1V1H A;  4GU4 A;  2OJ6 A;  3EOY A;  1QIU A;  2VRS A;  4ODB A;  2JJL A;  4XC5 A;  5MHS A;  1V1I A;  2BSF A;  3S6X A;  2BT8 A;  2BT7 A;  2OJ5 A; 
#chains in the Genus database with same CATH topology
 3TK5 B;  2BOH A;  3HO3 A;  3CEN L;  2W2N E;  1OB1 C;  4BDW A;  1MQ5 L;  4ATZ A;  3KQC L;  2VWN L;  3N8Y A;  2BOX A;  4BTT A;  2JKH L;  1HX2 A;  1BF9 A;  1YUF A;  4COX A;  1GK5 A;  2W3I B;  1ADX A;  2ADX A;  2KV4 A;  4RRX A;  4D62 A;  4Y6D B;  2W2P E;  2Y7X B;  1FE2 A;  3SOV A;  5K0H B;  3R05 A;  1CVU A;  1QHV A;  1F7M A;  4ISI L;  1IQF L;  4TGF A;  1ZAQ A;  2HOR A;  1U8C B;  4X8U L;  4G1M B;  1FAK L;  1G1S A;  1H7Z A;  1N1I A;  1WHE A;  1NT0 A;  3U7U G;  5I46 L;  3IIT B;  3LTF B;  5E8D A;  2G00 L;  1EMN A;  2J4I B;  4CW8 A;  1KLO A;  3PGH A;  2WGU A;  1P69 A;  5IKT A;  2P16 L;  1Z6E L;  2XBV L;  1HJ7 A;  1C5M F;  4D63 A;  1Q4G A;  4JZE L;  4M10 A;  5JB9 E;  1DDX A;  2WBW A;  2YGP A;  2BZU A;  3KQB L;  1LPZ A;  4XBM A;  1KIG L;  5JBA E;  2KNI A;  1CVW L;  2Y5F L;  2BQ6 A;  1V3X B;  1EGF A;  1KAC A;  1LMJ A;  4O1Z A;  3O8E A;  4XL1 A;  3ENS A;  2J38 B;  3GCX E;  3GIS X;  4RUT A;  4Z0L A;  2Q1J B;  1NFW B;  5JBB E;  1P0S L;  3HS6 A;  4GU4 A;  3V64 C;  1WU1 B;  2WPK E;  2W2O E;  4D0F A;  2QLK A;  4K6V A;  2VVC K;  4Z0K B;  1YUG A;  3MQE A;  2H9E L;  4C16 A;  2UWO B;  1ATA A;  3MDL A;  1UXE A;  5JVZ A;  1J9C L;  2MHP A;  2P3F N;  1HAF A;  4JYV L;  2VH6 B;  1YUK B;  1F7E A;  2PUQ L;  1NFU B;  4CUD A;  1COU A;  4XQB A;  1IOX A;  4AQT A;  1G1T A;  3N8Y B;  3SW2 A;  1I0U A;  2YGQ A;  2MGR A;  1PXX A;  3NTB A;  4BDX A;  1DX5 I;  2EI7 B;  1HRE A;  2W86 A;  1M1X B;  3TH3 L;  1TOZ A;  2IUM A;  1HT8 A;  3EXV A;  3N8X A;  4Z6A L;  2J34 B;  4JZD L;  1APO A;  3TGF A;  1K37 A;  2KL7 A;  2OYU P;  3TBD A;  4BXS A;  4PH9 A;  4D90 A;  1APQ A;  3POY A;  1FSB A;  2BQ7 A;  1IQL L;  4BTI A;  1P6A A;  1EZQ B;  2WPM E;  1UXA A;  2VVV L;  2P3U A;  2PR3 B;  1FFM A;  2YGO A;  3ZYJ B;  1DVA L;  5F19 A;  1CQE A;  1IQG L;  1NZI A;  4ZDG A;  2BZ6 L;  3M37 L;  1W7X L;  3FBY A;  1EPG A;  2P93 L;  2VWM K;  3CS7 L;  3LAQ A;  4MMX B;  2J95 B;  1IQE L;  1TPG A;  4FM5 A;  4CUE A;  1JBU L;  1MQ6 L;  2EI8 B;  1QIU A;  1KSN B;  1N7D A;  1YO8 A;  1QFK L;  2WZP P;  4ZHA B;  2XBX L;  6COX A;  1ATE A;  3N8W A;  3M36 L;  1LPG A;  2GD4 A;  2I9B A;  3NT1 A;  3F6U L;  3QCW A;  5CKQ A;  2W26 B;  3U73 A;  1G1R A;  1EBV A;  3P5B L;  1XKB A;  5CKM A;  4MMY B;  2OJ6 A;  2B7D L;  5IKV A;  3KQE L;  4XL8 A;  3OLU A;  2K2S B;  4ZAE B;  3ELA L;  4BXW A;  2VWL L;  2RHP A;  4ZXY L;  1XDT R;  2W2Q E;  2BT7 A;  3KCG L;  4RS0 A;  5F1A A;  2H9E C;  1CX2 A;  1UZQ A;  2P94 L;  4ODB A;  2VTW A;  2MGP A;  4WYJ A;  1IQI L;  3GCW E;  2M74 A;  1RFN B;  2FLR L;  2RNL A;  1MOX C;  3LC5 B;  1KNB A;  3N0I A;  1WHF A;  3LN1 A;  1IP0 A;  4LIY A;  1IQH L;  1LPK A;  4YT7 L;  1B9W A;  4OTY A;  2WYJ B;  3BQ4 A;  3N8V A;  3EGF A;  1IQK L;  1LK9 A;  3BT1 A;  2P26 A;  2NPR A;  2BO2 A;  3BT2 A;  2Y80 B;  2XBW L;  3LN0 A;  3ZPE A;  3QMO A;  4X8S L;  2WYG B;  3ZYG A;  1IQM L;  2Y81 B;  3K9X A;  1IJQ A;  1FJS L;  3ZPF A;  2UWL B;  3ASI A;  1DIY A;  2RA0 L;  1PTH A;  1CCF A;  4YT6 L;  1KLJ L;  2J1K C;  2Y38 A;  2TGF A;  3Q7D A;  2BT8 A;  1HT5 A;  2VH0 B;  5MHS A;  4NGA L;  3S6X A;  3ZYI B;  2WGT A;  1X7A L;  1TLE A;  2XC4 L;  4K6U A;  2WBV A;  2WG4 B;  1HAE A;  1O5D L;  2BMG A;  2P3T A;  2KB9 A;  2WG3 C;  3C9A C;  4OTJ A;  1EPI A;  2UWP B;  1L5G B;  2XC5 L;  1XKA L;  3BPS E;  2WPI E;  5JB8 E;  1NQL B;  3TK6 B;  2WST A;  1UZK A;  1CCV A;  2BZV A;  2P28 B;  1JV2 B;  2EI6 B;  4JZF L;  3H5C B;  1W8B L;  4GU3 A;  3IJE B;  5JW1 A;  4YZU B;  3LIW B;  2VJ3 A;  4RRZ A;  4MMZ B;  3KK6 A;  5IKR A;  1UZP A;  1EPJ A;  2HOX A;  4ZH8 B;  2BQW A;  3DEM A;  3RR3 A;  2XC0 L;  4CUF A;  3F1S B;  4RRY A;  4RRW A;  3LC3 B;  4LMF A;  1HRF A;  3OLT A;  4XC5 A;  3L89 A;  1EPH A;  3NJP C;  1U67 A;  4X8V L;  1K36 A;  3LTG D;  2J12 A;  1G1Q A;  2OJ5 A;  2I9A A;  2W3K B;  1IVO C;  1ATB A;  5CKN A;  2PHB B;  2AYL A;  4LOR A;  2WFT A;  4ISH L;  2IUN A;  1IQJ L;  1LMM A;  1PFX L;  3EOY A;  3SOQ A;  3CA7 A;  2Y82 B;  2VWO L;  1NOB A;  3HS5 A;  5JVY A;  1EAI C;  5L2Y L;  1KKE A;  2FD6 A;  2P3F L;  3KRK A;  2J2J A;  5EGM B;  1SZB A;  4Y7A B;  1NFX B;  5L30 L;  1IGX A;  3HPT A;  1IQN L;  1Z6C A;  2W9L C;  5CIS A;  3HS7 A;  5L2Z L;  1UXB A;  1JL9 A;  1HZ8 A;  3F0Y A;  3EXW A;  1ATD A;  1EQG A;  1UZJ A;  1V1H A;  1LQD A;  2WPL E;  4NG9 L;  2Y5G L;  3CNC A;  1HCG B;  1FAX L;  3FFG L;  1PGE A;  2BOK L;  2FLB L;  1FF7 A;  4A7I A;  1DQB A;  5JBC E;  2WPH E;  5COX A;  1AUT L;  2J94 B;  1IOE L;  2D1J B;  2FLG A;  2VRS A;  1F0S B;  2VVU L;  3HO5 A;  3NTG A;  2O39 A;  1NPE B;  2JJL A;  1V1I A;  3Q3K B;  2DDU A;  2XBY L;  4Y79 B;  2CJI B;  2Y7Z B;  4ZXX L;  3SOB B;  3HO4 A;  4O02 B;  1G2L B;  1NFY B;  1YGC L;  1EMO A;  4M11 A;  4D0E A;  5KN5 C;  4BTU A;  1P9J A;  2J2U B;  2BOU A;  4K6W A;  3L88 A;  1L3Y A;  1G2M B;  3FCS B;  1CEJ A;  3N8Z A;  4XQA A;  2W2M E;  3V65 B;  2WPJ E;  1F0R B;  2OYE P;  2P95 L;  4NA9 L;  5KIR A;  1IGZ A;  4Y76 B;  4Y7B B;  3CFW A;  2BSF A;  1URK A;  3KQD L;  3TZI A;  5IKQ A;  4E1G A;  2FZZ L;  4X8T L;  3N8W B;  3KL6 B;  1A3P A;  3QH0 A;  4A94 C;  2F9B L;  4CSY A;  1EQH A;  2K2T A;  4XLW A;  2Y5H L;  4JYU L;  1XFE A;  4Y71 B;  5FDQ A;  3QND A;  4K6T A;  1PRH A;  2WFX B;  1KLI L; 
#chains in the Genus database with same CATH homology
 1KKE A;  4GU3 A;  1V1H A;  4GU4 A;  2OJ6 A;  3EOY A;  1QIU A;  2VRS A;  4ODB A;  2JJL A;  4XC5 A;  5MHS A;  1V1I A;  2BSF A;  3S6X A;  2BT8 A;  2BT7 A;  2OJ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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