4GU4A

Crystal structure of the t1l reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
205
structure length
205
Chain Sequence
KIDSVLPPLTVREASGVRTLSFGYDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVADRFGMRTGTWTGQLQYQHPQLSWRANVTLNLMKVDDWLVLSFSQMTTNSIMADGKFVINFVSGLSSGWQTGDTEPSSTIDPLSTTFAAVQFLNNGQRIDAFRIMGVSEWTDGELEIKNYGGTYTGHTQVYWAPWTIMYPCNV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Viral protein
source organism Mammalian orthoreovirus 1
publication title The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus.
pubmed doi rcsb
molecule keywords Outer capsid protein sigma-1
total genus 30
structure length 205
sequence length 205
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.20 Mainly Beta Ribbon Laminin reovirus attachment protein sigma1; domain 1 4gu4A01
2.60.90.20 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Virus attachment protein , globular domain 4gu4A02
2OJ6A 1V1IA 3S6XA 2OJ5A 4XC5A 4ODBA 5MHSA 4GU3A 3EOYA 2JJLA 1QIUA 2VRSA 4GU4A 2BT7A 2BSFA 2BT8A 1KKEA 1V1HA
chains in the Genus database with same CATH superfamily
3QH0A 2Y5GL 3GCXE 2XC5L 5F1AA 5JVZA 3K9XA 2WFXB 4A7IA 3F1SB 1EMNA 1TLEA 1FJSL 5K0HB 2YGQA 4OTYA 1EGFA 2WPHE 3NT1A 3EOYA 3DEMA 2P94L 1ATDA 3EXWA 4A94C 2IUMA 2VTWA 2I9BA 2JJLA 3BPSE 1CCFA 2XBYL 1NFYB 1QFKL 2Y5FL 1W7XL 2FZZL 3Q7DA 1F7MA 1FE2A 3LAQA 4JZFL 1CVWL 1HCGB 4D90A 2K2SB 2VJ3A 4MMXB 1IQFL 1H7ZA 3L88A 1YUKB 2VVUL 1I0UA 4RRYA 1FAKL 2W2ME 4O1ZA 2Y81B 2P28B 2Y7XB 1IOXA 2J34B 4COXA 3NTGA 3QMOA 4RRZA 1X7AL 3L89A 1IP0A 1V3XB 2W3IB 4ZDGA 4BTTA 5KIRA 1UZJA 2UWPB 3OLTA 2FLRL 1NOBA 1ADXA 4D63A 4Y7AB 3KQBL 1EPHA 1URKA 3OLUA 4XQAA 5F19A 3NTBA 1LPZA 3QCWA 4Y7BB 2VVCK 4K6WA 3O8EA 2PHBB 2XBVL 4JZDL 3CFWA 2H9EC 1K37A 3U7UG 4Z6AL 2P95L 2WBVA 2WPLE 3IITB 2VWNL 5IKTA 3LC3B 2WFTA 1FFMA 1ATEA 3CENL 2QLKA 3HS6A 4X8UL 1MOXC 3LC5B 4GU3A 2J94B 2W2QE 2WYGB 2W2NE 3M37L 1EQGA 4ZXYL 1CX2A 5IKRA 1K36A 2UWLB 3SOQA 1SZBA 3FFGL 1HX2A 2BSFA 2TGFA 1IJQA 1MQ6L 2W86A 1DX5I 2WPKE 3ZPEA 1DQBA 1CEJA 1W8BL 1UXAA 3ELAL 4NGAL 1PTHA 3IJEB 1U67A 1EAIC 1FAXL 2WG4B 1F7EA 5EGMB 3HPTA 4RRXA 1IQIL 1IQHL 3SOBB 4RRWA 3KQCL 1UZKA 3N8WB 1IQKL 2MGRA 2P93L 2PR3B 1P9JA 2J12A 2J95B 2FLBL 2OYUP 3NJPC 1M1XB 4CUDA 3TBDA 3TK6B 4D0EA 1EBVA 1IGZA 3KK6A 1G2LB 2YGPA 6COXA 1JL9A 4ZAEB 1G1SA 1NT0A 1WHFA 4K6VA 4ATZA 3TH3L 1KLJL 1IQNL 2IUNA 1JBUL 3N0IA 3CS7L 4M11A 3F6UL 5L2YL 1B9WA 3KL6B 3POYA 2NPRA 2HOXA 1F0SB 1PRHA 4BXWA 5I46L 2YGOA 4YZUB 1V1IA 2WYJB 2WGTA 1XKAL 1P69A 1LMJA 1HZ8A 4D62A 4X8SL 2J38B 2RA0L 3R05A 4XBMA 1QHVA 5JB8E 4O02B 4XL8A 3ZYIB 1CQEA 4X8TL 5JVYA 4M10A 2WZPP 3GCWE 1PGEA 1HJ7A 1DDXA 3EGFA 4JYUL 2VH6B 1J9CL 3BQ4A 3TGFA 1KACA 4X8VL 1A3PA 1HREA 3N8ZA 2VVVL 4MMZB 2JKHL 2P3FN 4K6TA 1EPGA 1LK9A 1IQEL 5CKNA 2WPJE 4ISIL 1YO8A 3BT2A 4C16A 3MQEA 2AYLA 3KQDL 2FD6A 1EPJA 2J2UB 1HT5A 3S6XA 3QNDA 1HT8A 1QIUA 2KL7A 5CKMA 2P26A 4XQBA 2J4IB 1PFXL 2KB9A 2OJ6A 3SOVA 4JYVL 1IQML 2HORA 5JBCE 1LPGA 4BDWA 2BOKL 2KNIA 1AUTL 1FF7A 5FDQA 1ATBA 2GD4A 1IGXA 3RR3A 4BTUA 3TK5B 4CUEA 1Z6EL 3N8XA 2BOHA 4FM5A 2Y7ZB 5IKVA 3F0YA 4ZHAB 3HS7A 2DDUA 3H5CB 2H9EL 4XC5A 2UWOB 1G1TA 2M74A 1LQDA 2W3KB 1Z6CA 3LTFB 1CCVA 3BT1A 2KV4A 3P5BL 3HS5A 5COXA 1WHEA 1IVOC 5L2ZL 5IKQA 1NFUB 3CNCA 2K2TA 1COUA 2P3UA 2WG3C 2MHPA 1XFEA 5KN5C 1P6AA 1GK5A 4BDXA 1YUFA 4AQTA 2XC4L 4CW8A 1YUGA 3PGHA 2BQWA 4RUTA 1MQ5L 2G00L 4LORA 4D0FA 2EI7B 4WYJA 5JB9E 1C5MF 1P0SL 2BOXA 2BMGA 3LN1A 1O5DL 2F9BL 2P3TA 2W26B 2W9LC 3N8YB 1APOA 1KNBA 3SW2A 1XKBA 4Y71B 1CVUA 4LIYA 1DIYA 4Y79B 1IOEL 3HO4A 1NQLB 1G2MB 3LN0A 4G1MB 2J2JA 4TGFA 2VRSA 1NFXB 1UZQA 2WGUA 2I9AA 4XL1A 1LMMA 1N1IA 1L5GB 1LPKA 2B7DL 1JV2B 1UXBA 5JBAE 1KLIL 3V64C 3FBYA 1DVAL 3U73A 2XC0L 2VWLL 3Q3KB 5JW1A 1NFWB 1KKEA 2BQ6A 3M36L 5CKQA 1KIGL 2Y82B 4Y76B 4K6UA 1UXEA 2Y5HL 3N8VA 4PH9A 3GISX 4NG9L 2W2PE 3N8WA 1YGCL 3ENSA 1TPGA 2VH0B 2ADXA 1ZAQA 3MDLA 5MHSA 1FSBA 4ZXXL 1G1RA 3KCGL 2RHPA 4YT6L 1N7DA 2XBXL 4LMFA 3ZPFA 2BO2A 4GU4A 4MMYB 1BF9A 4Y6DB 1APQA 2OYEP 4E1GA 2BOUA 1KSNB 1U8CB 3V65B 3EXVA 2Y38A 2O39A 3KRKA 1RFNB 2P3FL 2P16L 1NZIA 3CA7A 4ISHL 5CISA 1Q4GA 2RNLA 2XBWL 2BT8A 4YT7L 2D1JB 2MGPA 2WBWA 1IQJL 3ZYJB 2EI8B 4Z0KB 4BTIA 1TOZA 2BT7A 3N8YA 3ZYGA 2Q1JB 4ODBA 3C9AC 1PXXA 2CJIB 2FLGA 1EZQB 4NA9L 1V1HA 2BQ7A 4CUFA 2W2OE 4OTJA 4BXSA 2PUQL 2J1KC 4CSYA 1ATAA 3FCSB 1IQGL 1XDTR 1HAFA 2WPME 1UZPA 2OJ5A 3KQEL 3LIWB 2BZVA 1F0RB 1NPEB 4JZEL 1HAEA 1EMOA 1EPIA 3TZIA 1L3YA 2Y80B 2WSTA 1KLOA 3HO5A 1IQLL 2VWMK 4XLWA 1EQHA 1G1QA 2EI6B 3HO3A 5JBBE 3LTGD 2WPIE 5E8DA 1OB1C 4RS0A 3ASIA 5L30L 2BZUA 4ZH8B 1WU1B 1HRFA 4Z0LA 2BZ6L 2VWOL
chains in the Genus database with same CATH topology
2OJ6A 1V1IA 3S6XA 2OJ5A 4XC5A 4ODBA 5MHSA 4GU3A 3EOYA 2JJLA 1QIUA 2VRSA 4GU4A 2BT7A 2BSFA 2BT8A 1KKEA 1V1HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OJ6 A;  1V1I A;  3S6X A;  2OJ5 A;  4XC5 A;  4ODB A;  5MHS A;  4GU3 A;  3EOY A;  2JJL A;  1QIU A;  2VRS A;  4GU4 A;  2BT7 A;  2BSF A;  2BT8 A;  1KKE A;  1V1H A; 
#chains in the Genus database with same CATH topology
 3QH0 A;  2Y5G L;  3GCX E;  2XC5 L;  5F1A A;  5JVZ A;  3K9X A;  2WFX B;  4A7I A;  3F1S B;  1EMN A;  1TLE A;  1FJS L;  5K0H B;  2YGQ A;  4OTY A;  1EGF A;  2WPH E;  3NT1 A;  3EOY A;  3DEM A;  2P94 L;  1ATD A;  3EXW A;  4A94 C;  2IUM A;  2VTW A;  2I9B A;  2JJL A;  3BPS E;  1CCF A;  2XBY L;  1NFY B;  1QFK L;  2Y5F L;  1W7X L;  2FZZ L;  3Q7D A;  1F7M A;  1FE2 A;  3LAQ A;  4JZF L;  1CVW L;  1HCG B;  4D90 A;  2K2S B;  2VJ3 A;  4MMX B;  1IQF L;  1H7Z A;  3L88 A;  1YUK B;  2VVU L;  1I0U A;  4RRY A;  1FAK L;  2W2M E;  4O1Z A;  2Y81 B;  2P28 B;  2Y7X B;  1IOX A;  2J34 B;  4COX A;  3NTG A;  3QMO A;  4RRZ A;  1X7A L;  3L89 A;  1IP0 A;  1V3X B;  2W3I B;  4ZDG A;  4BTT A;  5KIR A;  1UZJ A;  2UWP B;  3OLT A;  2FLR L;  1NOB A;  1ADX A;  4D63 A;  4Y7A B;  3KQB L;  1EPH A;  1URK A;  3OLU A;  4XQA A;  5F19 A;  3NTB A;  1LPZ A;  3QCW A;  4Y7B B;  2VVC K;  4K6W A;  3O8E A;  2PHB B;  2XBV L;  4JZD L;  3CFW A;  2H9E C;  1K37 A;  3U7U G;  4Z6A L;  2P95 L;  2WBV A;  2WPL E;  3IIT B;  2VWN L;  5IKT A;  3LC3 B;  2WFT A;  1FFM A;  1ATE A;  3CEN L;  2QLK A;  3HS6 A;  4X8U L;  1MOX C;  3LC5 B;  4GU3 A;  2J94 B;  2W2Q E;  2WYG B;  2W2N E;  3M37 L;  1EQG A;  4ZXY L;  1CX2 A;  5IKR A;  1K36 A;  2UWL B;  3SOQ A;  1SZB A;  3FFG L;  1HX2 A;  2BSF A;  2TGF A;  1IJQ A;  1MQ6 L;  2W86 A;  1DX5 I;  2WPK E;  3ZPE A;  1DQB A;  1CEJ A;  1W8B L;  1UXA A;  3ELA L;  4NGA L;  1PTH A;  3IJE B;  1U67 A;  1EAI C;  1FAX L;  2WG4 B;  1F7E A;  5EGM B;  3HPT A;  4RRX A;  1IQI L;  1IQH L;  3SOB B;  4RRW A;  3KQC L;  1UZK A;  3N8W B;  1IQK L;  2MGR A;  2P93 L;  2PR3 B;  1P9J A;  2J12 A;  2J95 B;  2FLB L;  2OYU P;  3NJP C;  1M1X B;  4CUD A;  3TBD A;  3TK6 B;  4D0E A;  1EBV A;  1IGZ A;  3KK6 A;  1G2L B;  2YGP A;  6COX A;  1JL9 A;  4ZAE B;  1G1S A;  1NT0 A;  1WHF A;  4K6V A;  4ATZ A;  3TH3 L;  1KLJ L;  1IQN L;  2IUN A;  1JBU L;  3N0I A;  3CS7 L;  4M11 A;  3F6U L;  5L2Y L;  1B9W A;  3KL6 B;  3POY A;  2NPR A;  2HOX A;  1F0S B;  1PRH A;  4BXW A;  5I46 L;  2YGO A;  4YZU B;  1V1I A;  2WYJ B;  2WGT A;  1XKA L;  1P69 A;  1LMJ A;  1HZ8 A;  4D62 A;  4X8S L;  2J38 B;  2RA0 L;  3R05 A;  4XBM A;  1QHV A;  5JB8 E;  4O02 B;  4XL8 A;  3ZYI B;  1CQE A;  4X8T L;  5JVY A;  4M10 A;  2WZP P;  3GCW E;  1PGE A;  1HJ7 A;  1DDX A;  3EGF A;  4JYU L;  2VH6 B;  1J9C L;  3BQ4 A;  3TGF A;  1KAC A;  4X8V L;  1A3P A;  1HRE A;  3N8Z A;  2VVV L;  4MMZ B;  2JKH L;  2P3F N;  4K6T A;  1EPG A;  1LK9 A;  1IQE L;  5CKN A;  2WPJ E;  4ISI L;  1YO8 A;  3BT2 A;  4C16 A;  3MQE A;  2AYL A;  3KQD L;  2FD6 A;  1EPJ A;  2J2U B;  1HT5 A;  3S6X A;  3QND A;  1HT8 A;  1QIU A;  2KL7 A;  5CKM A;  2P26 A;  4XQB A;  2J4I B;  1PFX L;  2KB9 A;  2OJ6 A;  3SOV A;  4JYV L;  1IQM L;  2HOR A;  5JBC E;  1LPG A;  4BDW A;  2BOK L;  2KNI A;  1AUT L;  1FF7 A;  5FDQ A;  1ATB A;  2GD4 A;  1IGX A;  3RR3 A;  4BTU A;  3TK5 B;  4CUE A;  1Z6E L;  3N8X A;  2BOH A;  4FM5 A;  2Y7Z B;  5IKV A;  3F0Y A;  4ZHA B;  3HS7 A;  2DDU A;  3H5C B;  2H9E L;  4XC5 A;  2UWO B;  1G1T A;  2M74 A;  1LQD A;  2W3K B;  1Z6C A;  3LTF B;  1CCV A;  3BT1 A;  2KV4 A;  3P5B L;  3HS5 A;  5COX A;  1WHE A;  1IVO C;  5L2Z L;  5IKQ A;  1NFU B;  3CNC A;  2K2T A;  1COU A;  2P3U A;  2WG3 C;  2MHP A;  1XFE A;  5KN5 C;  1P6A A;  1GK5 A;  4BDX A;  1YUF A;  4AQT A;  2XC4 L;  4CW8 A;  1YUG A;  3PGH A;  2BQW A;  4RUT A;  1MQ5 L;  2G00 L;  4LOR A;  4D0F A;  2EI7 B;  4WYJ A;  5JB9 E;  1C5M F;  1P0S L;  2BOX A;  2BMG A;  3LN1 A;  1O5D L;  2F9B L;  2P3T A;  2W26 B;  2W9L C;  3N8Y B;  1APO A;  1KNB A;  3SW2 A;  1XKB A;  4Y71 B;  1CVU A;  4LIY A;  1DIY A;  4Y79 B;  1IOE L;  3HO4 A;  1NQL B;  1G2M B;  3LN0 A;  4G1M B;  2J2J A;  4TGF A;  2VRS A;  1NFX B;  1UZQ A;  2WGU A;  2I9A A;  4XL1 A;  1LMM A;  1N1I A;  1L5G B;  1LPK A;  2B7D L;  1JV2 B;  1UXB A;  5JBA E;  1KLI L;  3V64 C;  3FBY A;  1DVA L;  3U73 A;  2XC0 L;  2VWL L;  3Q3K B;  5JW1 A;  1NFW B;  1KKE A;  2BQ6 A;  3M36 L;  5CKQ A;  1KIG L;  2Y82 B;  4Y76 B;  4K6U A;  1UXE A;  2Y5H L;  3N8V A;  4PH9 A;  3GIS X;  4NG9 L;  2W2P E;  3N8W A;  1YGC L;  3ENS A;  1TPG A;  2VH0 B;  2ADX A;  1ZAQ A;  3MDL A;  5MHS A;  1FSB A;  4ZXX L;  1G1R A;  3KCG L;  2RHP A;  4YT6 L;  1N7D A;  2XBX L;  4LMF A;  3ZPF A;  2BO2 A;  4GU4 A;  4MMY B;  1BF9 A;  4Y6D B;  1APQ A;  2OYE P;  4E1G A;  2BOU A;  1KSN B;  1U8C B;  3V65 B;  3EXV A;  2Y38 A;  2O39 A;  3KRK A;  1RFN B;  2P3F L;  2P16 L;  1NZI A;  3CA7 A;  4ISH L;  5CIS A;  1Q4G A;  2RNL A;  2XBW L;  2BT8 A;  4YT7 L;  2D1J B;  2MGP A;  2WBW A;  1IQJ L;  3ZYJ B;  2EI8 B;  4Z0K B;  4BTI A;  1TOZ A;  2BT7 A;  3N8Y A;  3ZYG A;  2Q1J B;  4ODB A;  3C9A C;  1PXX A;  2CJI B;  2FLG A;  1EZQ B;  4NA9 L;  1V1H A;  2BQ7 A;  4CUF A;  2W2O E;  4OTJ A;  4BXS A;  2PUQ L;  2J1K C;  4CSY A;  1ATA A;  3FCS B;  1IQG L;  1XDT R;  1HAF A;  2WPM E;  1UZP A;  2OJ5 A;  3KQE L;  3LIW B;  2BZV A;  1F0R B;  1NPE B;  4JZE L;  1HAE A;  1EMO A;  1EPI A;  3TZI A;  1L3Y A;  2Y80 B;  2WST A;  1KLO A;  3HO5 A;  1IQL L;  2VWM K;  4XLW A;  1EQH A;  1G1Q A;  2EI6 B;  3HO3 A;  5JBB E;  3LTG D;  2WPI E;  5E8D A;  1OB1 C;  4RS0 A;  3ASI A;  5L30 L;  2BZU A;  4ZH8 B;  1WU1 B;  1HRF A;  4Z0L A;  2BZ6 L;  2VWO L; 
#chains in the Genus database with same CATH homology
 2OJ6 A;  1V1I A;  3S6X A;  2OJ5 A;  4XC5 A;  4ODB A;  5MHS A;  4GU3 A;  3EOY A;  2JJL A;  1QIU A;  2VRS A;  4GU4 A;  2BT7 A;  2BSF A;  2BT8 A;  1KKE A;  1V1H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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