4GU4A

Crystal structure of the t1l reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
205
structure length
205
Chain Sequence
KIDSVLPPLTVREASGVRTLSFGYDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVADRFGMRTGTWTGQLQYQHPQLSWRANVTLNLMKVDDWLVLSFSQMTTNSIMADGKFVINFVSGLSSGWQTGDTEPSSTIDPLSTTFAAVQFLNNGQRIDAFRIMGVSEWTDGELEIKNYGGTYTGHTQVYWAPWTIMYPCNV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus.
pubmed doi rcsb
molecule tags Viral protein
source organism Mammalian orthoreovirus 1
molecule keywords Outer capsid protein sigma-1
total genus 30
structure length 205
sequence length 205
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.20 Mainly Beta Ribbon Laminin reovirus attachment protein sigma1; domain 1 4gu4A01
2.60.90.20 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Virus attachment protein , globular domain 4gu4A02
2BT7A 1QIUA 4GU4A 4ODBA 3S6XA 2OJ6A 1V1HA 2BT8A 4XC5A 5MHSA 2BSFA 1KKEA 2VRSA 2OJ5A 1V1IA 2JJLA 3EOYA 4GU3A
chains in the Genus database with same CATH superfamily
1IQHL 3OLUA 2WBVA 1IGZA 3POYA 4K6UA 4JZEL 2FZZL 1FJSL 1EGFA 1IQIL 2P3FL 4O02B 1EZQB 2BQ6A 3BPSE 2BSFA 5L2YL 2XC5L 3M36L 2HORA 4ZDGA 2G00L 1WHFA 4Y6DB 3GCWE 3LAQA 1CCFA 3HO3A 2VTWA 1G2LB 5L2ZL 2XBYL 4WYJA 2FLBL 4XC5A 2P93L 4ZH8B 3L89A 1GK5A 2VJ3A 2AYLA 2Q1JB 2VVCK 4K6VA 2BMGA 3TBDA 1IP0A 4YT7L 2NPRA 4CSYA 1HT5A 2H9EC 2UWLB 4ZAEB 5JBAE 3N8ZA 4BTUA 2Y5HL 5JVYA 3DEMA 2W2QE 3CS7L 4JYUL 3L88A 3C9AC 5KN5C 1CCVA 1EBVA 3NT1A 2WGUA 3N8XA 1V1HA 2K2TA 3ASIA 4RUTA 2VWOL 1EPIA 3TGFA 4ODBA 4ISIL 1ZAQA 3Q7DA 3ZPFA 4X8UL 2WPKE 4JZDL 1CEJA 2P3TA 1IJQA 2W3IB 2W2OE 4RRWA 2K2SB 4RS0A 4O1ZA 5CKQA 2TGFA 1P0SL 3V65B 2WPLE 1LMJA 4MMZB 4LMFA 2FD6A 3P5BL 3F1SB 1LMMA 1XFEA 2DDUA 4BTIA 1DIYA 2YGQA 4D0FA 2RA0L 1HT8A 1HAEA 1PRHA 1FSBA 4NGAL 5JBBE 2VWNL 1SZBA 2QLKA 1NFYB 1IVOC 5K0HB 2XBWL 2OJ6A 1AUTL 1MQ6L 1WHEA 2M74A 5JVZA 1CVUA 1PFXL 2BOUA 3ZYJB 3RR3A 1QHVA 1P9JA 4CUDA 2OYUP 4GU3A 1NPEB 2W3KB 2WGTA 3BQ4A 1KLOA 3Q3KB 4OTJA 3ENSA 4JZFL 3EXWA 1V1IA 2W26B 2P26A 1FF7A 1NFXB 2PHBB 2VH0B 1IQLL 2BQ7A 4XBMA 1LPGA 2UWOB 5E8DA 5IKRA 3F0YA 3FBYA 1IQFL 5IKTA 1DX5I 1IOEL 4XQBA 2WBWA 5IKVA 2W9LC 1EMNA 1G1RA 1N7DA 3KCGL 3NJPC 4A94C 4D63A 3HS7A 4BXSA 1F0SB 1KACA 1EAIC 1G1TA 1EQHA 2J2UB 1G1QA 4OTYA 3N0IA 4ZXXL 2FLGA 3NTGA 1NFWB 6COXA 3R05A 5MHSA 3PGHA 4D62A 1FFMA 1EMOA 4YT6L 1Z6CA 2VH6B 3N8VA 1FAXL 1APOA 2KNIA 2Y38A 1IQGL 1HCGB 1HZ8A 4D90A 4ZHAB 1KLJL 1EPGA 2J34B 1F0RB 1JV2B 2WFTA 2VRSA 2IUMA 3ELAL 2OYEP 1K36A 3CNCA 1JBUL 3FFGL 1RFNB 4LORA 4A7IA 5CKNA 1HRFA 1XKAL 2HOXA 2W2NE 4ATZA 3KQEL 3LTGD 2WFXB 1YGCL 1UZQA 1C5MF 1W8BL 3CENL 2BZ6L 4G1MB 3ZYIB 1DDXA 4M11A 5F19A 4X8VL 2D1JB 5JW1A 4XL1A 1I0UA 4BXWA 3KK6A 3KQBL 1EPJA 4Z0LA 3HS5A 3BT2A 2I9AA 1CVWL 2WG4B 1LPKA 2BT8A 1UZPA 2EI6B 4E1GA 3EOYA 1WU1B 2F9BL 2H9EL 3CFWA 1B9WA 1ATDA 1LPZA 2VWLL 1HAFA 1TOZA 4CUEA 3LN1A 3H5CB 1UXBA 1UZKA 2BZVA 1OB1C 3EXVA 5FDQA 2WZPP 1N1IA 2W2ME 1V3XB 1P6AA 2O39A 1MQ5L 1TPGA 4K6TA 3GISX 1IQML 2UWPB 2MHPA 2B7DL 4XL8A 3ZPEA 1NT0A 3N8YA 1A3PA 2VVVL 1NOBA 2P95L 3GCXE 2Y5GL 1MOXC 4Y71B 3MQEA 2BOHA 3TK6B 4RRYA 2J2JA 1Q4GA 3S6XA 4AQTA 1P69A 3QNDA 1DVAL 1NFUB 1M1XB 1U8CB 3QCWA 2VWMK 1L3YA 2Y5FL 1W7XL 3QMOA 4GU4A 3IITB 3KQDL 2KB9A 2J38B 1KLIL 3FCSB 3M37L 1IQJL 2EI7B 1H7ZA 2P16L 2WYJB 2Y7ZB 3ZYGA 1YUKB 3KRKA 2WSTA 2XBXL 3SOBB 3KQCL 2ADXA 4JYVL 4TGFA 4XLWA 1EQGA 3U7UG 1ATEA 1ATBA 1TLEA 2BQWA 3MDLA 1F7MA 4MMXB 2Y82B 2RHPA 4NG9L 1BF9A 3HPTA 5JB8E 4BDXA 4Y76B 1Z6EL 2BOXA 3LTFB 2W86A 2Y81B 1HJ7A 2WPME 1NQLB 2Y7XB 2MGPA 3IJEB 2J12A 2BO2A 4FM5A 3U73A 2IUNA 4BDWA 2KV4A 1EPHA 3TZIA 3EGFA 1IOXA 2J95B 3TH3L 4CW8A 4ISHL 1PTHA 2PUQL 2J1KC 4X8SL 4Z6AL 1O5DL 1KSNB 3HS6A 3HO5A 3N8WA 4XQAA 2XC0L 4K6WA 1IQKL 1QIUA 4CUFA 4ZXYL 3LC5B 1KKEA 2GD4A 2JJLA 4COXA 2KL7A 3NTBA 2J94B 2J4IB 4NA9L 1X7AL 4Y7BB 2FLRL 2CJIB 2XC4L 2Y80B 1G1SA 4LIYA 1UXAA 1PXXA 4RRZA 2YGOA 2P3FN 3LC3B 4C16A 3HO4A 2YGPA 4YZUB 3N8WB 1XDTR 1APQA 2P94L 4PH9A 3LIWB 2BOKL 1K37A 2EI8B 2WYGB 4D0EA 1ADXA 2WG3C 3LN0A 3O8EA 2BZUA 1CX2A 1KIGL 1HX2A 5KIRA 5L30L 1QFKL 2BT7A 2P28B 5IKQA 1F7EA 3CA7A 1G2MB 1UXEA 3OLTA 5CKMA 2PR3B 1PGEA 1YUFA 1J9CL 2MGRA 2VVUL 1LQDA 1URKA 5CISA 1U67A 1COUA 2XBVL 1XKBA 1FE2A 3QH0A 4M10A 1NZIA 5F1AA 3F6UL 1IQEL 2WPJE 1ATAA 2P3UA 1JL9A 4Y7AB 1L5GB 5EGMB 5JB9E 3KL6B 4X8TL 3TK5B 3K9XA 5I46L 4MMYB 1UZJA 2I9BA 1YUGA 1IQNL 2OJ5A 1CQEA 4Z0KB 4BTTA 3SW2A 1FAKL 1LK9A 3SOVA 3BT1A 5JBCE 2RNLA 2JKHL 3N8YB 2WPIE 2W2PE 3SOQA 1YO8A 1DQBA 5COXA 1HREA 1KNBA 2WPHE 1IGXA 4Y79B 4RRXA 3V64C
chains in the Genus database with same CATH topology
2BT7A 1QIUA 4GU4A 4ODBA 3S6XA 2OJ6A 1V1HA 2BT8A 4XC5A 5MHSA 2BSFA 1KKEA 2VRSA 2OJ5A 1V1IA 2JJLA 3EOYA 4GU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BT7 A;  1QIU A;  4GU4 A;  4ODB A;  3S6X A;  2OJ6 A;  1V1H A;  2BT8 A;  4XC5 A;  5MHS A;  2BSF A;  1KKE A;  2VRS A;  2OJ5 A;  1V1I A;  2JJL A;  3EOY A;  4GU3 A; 
#chains in the Genus database with same CATH topology
 1IQH L;  3OLU A;  2WBV A;  1IGZ A;  3POY A;  4K6U A;  4JZE L;  2FZZ L;  1FJS L;  1EGF A;  1IQI L;  2P3F L;  4O02 B;  1EZQ B;  2BQ6 A;  3BPS E;  2BSF A;  5L2Y L;  2XC5 L;  3M36 L;  2HOR A;  4ZDG A;  2G00 L;  1WHF A;  4Y6D B;  3GCW E;  3LAQ A;  1CCF A;  3HO3 A;  2VTW A;  1G2L B;  5L2Z L;  2XBY L;  4WYJ A;  2FLB L;  4XC5 A;  2P93 L;  4ZH8 B;  3L89 A;  1GK5 A;  2VJ3 A;  2AYL A;  2Q1J B;  2VVC K;  4K6V A;  2BMG A;  3TBD A;  1IP0 A;  4YT7 L;  2NPR A;  4CSY A;  1HT5 A;  2H9E C;  2UWL B;  4ZAE B;  5JBA E;  3N8Z A;  4BTU A;  2Y5H L;  5JVY A;  3DEM A;  2W2Q E;  3CS7 L;  4JYU L;  3L88 A;  3C9A C;  5KN5 C;  1CCV A;  1EBV A;  3NT1 A;  2WGU A;  3N8X A;  1V1H A;  2K2T A;  3ASI A;  4RUT A;  2VWO L;  1EPI A;  3TGF A;  4ODB A;  4ISI L;  1ZAQ A;  3Q7D A;  3ZPF A;  4X8U L;  2WPK E;  4JZD L;  1CEJ A;  2P3T A;  1IJQ A;  2W3I B;  2W2O E;  4RRW A;  2K2S B;  4RS0 A;  4O1Z A;  5CKQ A;  2TGF A;  1P0S L;  3V65 B;  2WPL E;  1LMJ A;  4MMZ B;  4LMF A;  2FD6 A;  3P5B L;  3F1S B;  1LMM A;  1XFE A;  2DDU A;  4BTI A;  1DIY A;  2YGQ A;  4D0F A;  2RA0 L;  1HT8 A;  1HAE A;  1PRH A;  1FSB A;  4NGA L;  5JBB E;  2VWN L;  1SZB A;  2QLK A;  1NFY B;  1IVO C;  5K0H B;  2XBW L;  2OJ6 A;  1AUT L;  1MQ6 L;  1WHE A;  2M74 A;  5JVZ A;  1CVU A;  1PFX L;  2BOU A;  3ZYJ B;  3RR3 A;  1QHV A;  1P9J A;  4CUD A;  2OYU P;  4GU3 A;  1NPE B;  2W3K B;  2WGT A;  3BQ4 A;  1KLO A;  3Q3K B;  4OTJ A;  3ENS A;  4JZF L;  3EXW A;  1V1I A;  2W26 B;  2P26 A;  1FF7 A;  1NFX B;  2PHB B;  2VH0 B;  1IQL L;  2BQ7 A;  4XBM A;  1LPG A;  2UWO B;  5E8D A;  5IKR A;  3F0Y A;  3FBY A;  1IQF L;  5IKT A;  1DX5 I;  1IOE L;  4XQB A;  2WBW A;  5IKV A;  2W9L C;  1EMN A;  1G1R A;  1N7D A;  3KCG L;  3NJP C;  4A94 C;  4D63 A;  3HS7 A;  4BXS A;  1F0S B;  1KAC A;  1EAI C;  1G1T A;  1EQH A;  2J2U B;  1G1Q A;  4OTY A;  3N0I A;  4ZXX L;  2FLG A;  3NTG A;  1NFW B;  6COX A;  3R05 A;  5MHS A;  3PGH A;  4D62 A;  1FFM A;  1EMO A;  4YT6 L;  1Z6C A;  2VH6 B;  3N8V A;  1FAX L;  1APO A;  2KNI A;  2Y38 A;  1IQG L;  1HCG B;  1HZ8 A;  4D90 A;  4ZHA B;  1KLJ L;  1EPG A;  2J34 B;  1F0R B;  1JV2 B;  2WFT A;  2VRS A;  2IUM A;  3ELA L;  2OYE P;  1K36 A;  3CNC A;  1JBU L;  3FFG L;  1RFN B;  4LOR A;  4A7I A;  5CKN A;  1HRF A;  1XKA L;  2HOX A;  2W2N E;  4ATZ A;  3KQE L;  3LTG D;  2WFX B;  1YGC L;  1UZQ A;  1C5M F;  1W8B L;  3CEN L;  2BZ6 L;  4G1M B;  3ZYI B;  1DDX A;  4M11 A;  5F19 A;  4X8V L;  2D1J B;  5JW1 A;  4XL1 A;  1I0U A;  4BXW A;  3KK6 A;  3KQB L;  1EPJ A;  4Z0L A;  3HS5 A;  3BT2 A;  2I9A A;  1CVW L;  2WG4 B;  1LPK A;  2BT8 A;  1UZP A;  2EI6 B;  4E1G A;  3EOY A;  1WU1 B;  2F9B L;  2H9E L;  3CFW A;  1B9W A;  1ATD A;  1LPZ A;  2VWL L;  1HAF A;  1TOZ A;  4CUE A;  3LN1 A;  3H5C B;  1UXB A;  1UZK A;  2BZV A;  1OB1 C;  3EXV A;  5FDQ A;  2WZP P;  1N1I A;  2W2M E;  1V3X B;  1P6A A;  2O39 A;  1MQ5 L;  1TPG A;  4K6T A;  3GIS X;  1IQM L;  2UWP B;  2MHP A;  2B7D L;  4XL8 A;  3ZPE A;  1NT0 A;  3N8Y A;  1A3P A;  2VVV L;  1NOB A;  2P95 L;  3GCX E;  2Y5G L;  1MOX C;  4Y71 B;  3MQE A;  2BOH A;  3TK6 B;  4RRY A;  2J2J A;  1Q4G A;  3S6X A;  4AQT A;  1P69 A;  3QND A;  1DVA L;  1NFU B;  1M1X B;  1U8C B;  3QCW A;  2VWM K;  1L3Y A;  2Y5F L;  1W7X L;  3QMO A;  4GU4 A;  3IIT B;  3KQD L;  2KB9 A;  2J38 B;  1KLI L;  3FCS B;  3M37 L;  1IQJ L;  2EI7 B;  1H7Z A;  2P16 L;  2WYJ B;  2Y7Z B;  3ZYG A;  1YUK B;  3KRK A;  2WST A;  2XBX L;  3SOB B;  3KQC L;  2ADX A;  4JYV L;  4TGF A;  4XLW A;  1EQG A;  3U7U G;  1ATE A;  1ATB A;  1TLE A;  2BQW A;  3MDL A;  1F7M A;  4MMX B;  2Y82 B;  2RHP A;  4NG9 L;  1BF9 A;  3HPT A;  5JB8 E;  4BDX A;  4Y76 B;  1Z6E L;  2BOX A;  3LTF B;  2W86 A;  2Y81 B;  1HJ7 A;  2WPM E;  1NQL B;  2Y7X B;  2MGP A;  3IJE B;  2J12 A;  2BO2 A;  4FM5 A;  3U73 A;  2IUN A;  4BDW A;  2KV4 A;  1EPH A;  3TZI A;  3EGF A;  1IOX A;  2J95 B;  3TH3 L;  4CW8 A;  4ISH L;  1PTH A;  2PUQ L;  2J1K C;  4X8S L;  4Z6A L;  1O5D L;  1KSN B;  3HS6 A;  3HO5 A;  3N8W A;  4XQA A;  2XC0 L;  4K6W A;  1IQK L;  1QIU A;  4CUF A;  4ZXY L;  3LC5 B;  1KKE A;  2GD4 A;  2JJL A;  4COX A;  2KL7 A;  3NTB A;  2J94 B;  2J4I B;  4NA9 L;  1X7A L;  4Y7B B;  2FLR L;  2CJI B;  2XC4 L;  2Y80 B;  1G1S A;  4LIY A;  1UXA A;  1PXX A;  4RRZ A;  2YGO A;  2P3F N;  3LC3 B;  4C16 A;  3HO4 A;  2YGP A;  4YZU B;  3N8W B;  1XDT R;  1APQ A;  2P94 L;  4PH9 A;  3LIW B;  2BOK L;  1K37 A;  2EI8 B;  2WYG B;  4D0E A;  1ADX A;  2WG3 C;  3LN0 A;  3O8E A;  2BZU A;  1CX2 A;  1KIG L;  1HX2 A;  5KIR A;  5L30 L;  1QFK L;  2BT7 A;  2P28 B;  5IKQ A;  1F7E A;  3CA7 A;  1G2M B;  1UXE A;  3OLT A;  5CKM A;  2PR3 B;  1PGE A;  1YUF A;  1J9C L;  2MGR A;  2VVU L;  1LQD A;  1URK A;  5CIS A;  1U67 A;  1COU A;  2XBV L;  1XKB A;  1FE2 A;  3QH0 A;  4M10 A;  1NZI A;  5F1A A;  3F6U L;  1IQE L;  2WPJ E;  1ATA A;  2P3U A;  1JL9 A;  4Y7A B;  1L5G B;  5EGM B;  5JB9 E;  3KL6 B;  4X8T L;  3TK5 B;  3K9X A;  5I46 L;  4MMY B;  1UZJ A;  2I9B A;  1YUG A;  1IQN L;  2OJ5 A;  1CQE A;  4Z0K B;  4BTT A;  3SW2 A;  1FAK L;  1LK9 A;  3SOV A;  3BT1 A;  5JBC E;  2RNL A;  2JKH L;  3N8Y B;  2WPI E;  2W2P E;  3SOQ A;  1YO8 A;  1DQB A;  5COX A;  1HRE A;  1KNB A;  2WPH E;  1IGX A;  4Y79 B;  4RRX A;  3V64 C; 
#chains in the Genus database with same CATH homology
 2BT7 A;  1QIU A;  4GU4 A;  4ODB A;  3S6X A;  2OJ6 A;  1V1H A;  2BT8 A;  4XC5 A;  5MHS A;  2BSF A;  1KKE A;  2VRS A;  2OJ5 A;  1V1I A;  2JJL A;  3EOY A;  4GU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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