4GU3A

Crystal structure of the t1l reovirus attachment protein sigma1 in complex with the gm2 glycan
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
205
structure length
205
Chain Sequence
KIDSVLPPLTVREASGVRTLSFGYDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVADRFGMRTGTWTGQLQYQHPQLSWRANVTLNLMKVDDWLVLSFSQMTTNSIMADGKFVINFVSGLSSGWQTGDTEPSSTIDPLSTTFAAVQFLNNGQRIDAFRIMGVSEWTDGELEIKNYGGTYTGHTQVYWAPWTIMYPCNV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus.
pubmed doi rcsb
molecule tags Viral protein
source organism Mammalian orthoreovirus 1
molecule keywords Outer capsid protein sigma-1
total genus 30
structure length 205
sequence length 205
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.20 Mainly Beta Ribbon Laminin reovirus attachment protein sigma1; domain 1 4gu3A01
2.60.90.20 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Virus attachment protein , globular domain 4gu3A02
4XC5A 2BT7A 2VRSA 2OJ5A 4ODBA 4GU4A 2BSFA 3EOYA 1QIUA 1V1IA 2BT8A 5MHSA 1KKEA 3S6XA 1V1HA 2JJLA 4GU3A 2OJ6A
chains in the Genus database with same CATH superfamily
2OJ5A 5JBAE 2KB9A 2WPHE 2WZPP 1IQJL 3CENL 1P69A 2WPME 4BTIA 3CFWA 3HS6A 1P9JA 1TLEA 4C16A 1Z6EL 4NGAL 1FE2A 1KNBA 5L2ZL 2YGOA 1Z6CA 1N7DA 2J4IB 4OTJA 1MQ6L 5JVZA 4JZEL 1CEJA 2JJLA 4X8TL 3LTGD 1CVUA 3EXWA 3CNCA 3N8XA 1PRHA 1KKEA 3MQEA 2WG4B 1U8CB 2VVVL 3LC3B 4G1MB 1KSNB 2XBXL 3TBDA 2FZZL 4XLWA 2W3IB 2OYUP 1YUKB 2EI7B 2J2UB 1EPIA 4WYJA 4M10A 4XC5A 2FLRL 4K6WA 1LK9A 2VWMK 5L30L 2HOXA 2VVCK 3Q7DA 4ATZA 2W3KB 3RR3A 3V64C 2BMGA 5CKQA 1I0UA 1IP0A 1G1SA 1CVWL 2WGTA 1PGEA 1CCVA 3NTGA 4NA9L 2BOUA 2MGPA 3LIWB 3NT1A 4CW8A 5CKNA 2DDUA 3CS7L 3QNDA 5CISA 1DX5I 1JV2B 2VWOL 3ZPEA 2F9BL 2WPJE 2W2ME 1A3PA 3POYA 1IGXA 2J2JA 1NZIA 3LN1A 4AQTA 3TK5B 4BTTA 2UWOB 1K36A 4ZXXL 3DEMA 5FDQA 3HO5A 2P3TA 3H5CB 2OYEP 1UXEA 2RHPA 3V65B 2PUQL 1N1IA 3CA7A 4K6TA 1WHFA 2NPRA 2P94L 5L2YL 2Q1JB 2BOKL 2P95L 2TGFA 5JB9E 1XKBA 1QHVA 3MDLA 2VWNL 2VRSA 2W86A 4ZAEB 5KN5C 2J12A 1HCGB 2J95B 3SOBB 4BDXA 1EBVA 2WYJB 1ATEA 2K2TA 1CCFA 4K6VA 1IQKL 5JVYA 1PTHA 2VWLL 4A7IA 1KLJL 2WBWA 4E1GA 1OB1C 1MQ5L 2WYGB 5KIRA 1HT5A 3EXVA 1YGCL 1CQEA 4Z6AL 3TH3L 2Y82B 1NFXB 3N8YA 4LORA 3KRKA 1F7MA 3PGHA 4YT6L 1C5MF 5EGMB 4X8VL 2IUMA 1IOEL 1HZ8A 5F1AA 1DQBA 1HREA 3NTBA 4XL8A 5IKQA 2I9AA 2W2PE 1M1XB 2W2QE 2FLBL 4JZFL 1HT8A 1UZJA 1TPGA 2I9BA 3KQBL 3QH0A 2BZ6L 3LC5B 1Q4GA 2RA0L 1W8BL 1DIYA 1NFYB 4OTYA 3ZYIB 1KACA 4BDWA 2J94B 3QMOA 1NT0A 5MHSA 1XDTR 4JYUL 1APQA 4ZDGA 4RRWA 2KV4A 2VJ3A 1GK5A 1IQIL 3N8ZA 5COXA 4RRZA 1DVAL 3ZPFA 3M36L 1O5DL 2BT7A 2QLKA 1F0RB 2VH0B 1NQLB 3O8EA 2G00L 2P26A 3EOYA 2VH6B 3KCGL 1EPGA 1L5GB 2BOHA 1LPZA 2BQWA 1HAFA 1H7ZA 1LPKA 2YGPA 4K6UA 3HS7A 2MGRA 3KQDL 3TK6B 3F1SB 2H9EC 2XBWL 1U67A 3OLTA 2Y7XB 4YT7L 1FFMA 1IQEL 3U73A 5JBCE 5CKMA 5JBBE 4MMZB 2Y81B 2WPLE 4BTUA 4LIYA 1UZKA 3KK6A 1PXXA 4BXWA 3N8VA 4MMXB 1JBUL 2J38B 5E8DA 1IGZA 3LTFB 1IJQA 1HJ7A 2W9LC 2FLGA 3EGFA 1NOBA 2WGUA 4XQBA 3BPSE 4Y7BB 3N0IA 1COUA 2D1JB 4O02B 3FBYA 4O1ZA 1FAKL 2J34B 4MMYB 3BT2A 2VTWA 2PHBB 1NFWB 5JW1A 3KQEL 4Y76B 4JZDL 2W2NE 1HAEA 3N8YB 3N8WB 5I46L 1F0SB 4XBMA 1HRFA 2EI6B 2KNIA 4ZHAB 4RRXA 1HX2A 3LAQA 2BT8A 2P93L 4ISIL 1QFKL 4X8SL 5JB8E 1EGFA 2BQ7A 4CSYA 2W26B 1X7AL 2W2OE 1KIGL 3Q3KB 2MHPA 2Y5HL 4Z0LA 3FFGL 1IQHL 4CUDA 1W7XL 1F7EA 2M74A 1EMNA 3TZIA 1URKA 2EI8B 4M11A 1SZBA 4X8UL 1EQHA 1IQFL 1V1HA 1YUFA 1UXBA 3HPTA 1LMJA 4Y6DB 1G1QA 4ZH8B 3FCSB 2BOXA 1EZQB 4JYVL 2WFXB 2AYLA 2WPKE 1DDXA 3HO3A 2HORA 3OLUA 2B7DL 3K9XA 1ATBA 4Y71B 1IQML 4XL1A 3KL6B 2UWLB 2O39A 1ADXA 3ZYJB 4D90A 3U7UG 4XQAA 2Y7ZB 1V3XB 1LQDA 3M37L 1KLIL 1XFEA 1EPHA 3LN0A 4NG9L 2Y38A 1IOXA 3ZYGA 4Y79B 1ATDA 4RUTA 2WFTA 1JL9A 2BO2A 4ZXYL 2BQ6A 3GCWE 1FSBA 3F0YA 2BZUA 1IVOC 4FM5A 1B9WA 3KQCL 4ODBA 5IKRA 2FD6A 3SW2A 1BF9A 3C9AC 4TGFA 1L3YA 2PR3B 2JKHL 1EPJA 1G2LB 1NFUB 2P3FN 4RRYA 1UXAA 1MOXC 1V1IA 2XC0L 4D0FA 3BT1A 2P28B 1P0SL 1UZPA 2YGQA 4COXA 3GCXE 1CX2A 2BSFA 1K37A 4CUFA 2WPIE 4YZUB 2K2SB 1APOA 3QCWA 5K0HB 3L88A 3R05A 2WBVA 2WG3C 3ELAL 2VVUL 2BZVA 1QIUA 2Y5FL 4Y7AB 3GISX 1KLOA 1IQNL 1EMOA 2WSTA 2UWPB 2Y80B 1YO8A 3ASIA 3ENSA 1XKAL 1IQGL 2XC4L 4A94C 3S6XA 2XBVL 1G1RA 3L89A 1G2MB 2P3UA 3HS5A 3BQ4A 2H9EL 1NPEB 4CUEA 1RFNB 1TOZA 3HO4A 2P3FL 1J9CL 3IITB 2IUNA 4D63A 1WU1B 1LMMA 3SOQA 1PFXL 1FF7A 3IJEB 1EQGA 2XBYL 2OJ6A 1G1TA 1AUTL 4LMFA 2GD4A 5F19A 3F6UL 2KL7A 3NJPC 3TGFA 1IQLL 3SOVA 4ISHL 4D0EA 2Y5GL 1YUGA 5IKTA 1LPGA 1WHEA 1P6AA 2ADXA 2RNLA 1EAIC 1FJSL 2J1KC 4GU4A 1UZQA 1FAXL 1ATAA 5IKVA 3N8WA 4D62A 2XC5L 2CJIB 4Z0KB 4PH9A 1ZAQA 2P16L 3P5BL 4RS0A 4BXSA 6COXA 4GU3A
chains in the Genus database with same CATH topology
4XC5A 2BT7A 2VRSA 2OJ5A 4ODBA 4GU4A 2BSFA 3EOYA 1QIUA 1V1IA 2BT8A 5MHSA 1KKEA 3S6XA 1V1HA 2JJLA 4GU3A 2OJ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XC5 A;  2BT7 A;  2VRS A;  2OJ5 A;  4ODB A;  4GU4 A;  2BSF A;  3EOY A;  1QIU A;  1V1I A;  2BT8 A;  5MHS A;  1KKE A;  3S6X A;  1V1H A;  2JJL A;  4GU3 A;  2OJ6 A; 
#chains in the Genus database with same CATH topology
 2OJ5 A;  5JBA E;  2KB9 A;  2WPH E;  2WZP P;  1IQJ L;  3CEN L;  1P69 A;  2WPM E;  4BTI A;  3CFW A;  3HS6 A;  1P9J A;  1TLE A;  4C16 A;  1Z6E L;  4NGA L;  1FE2 A;  1KNB A;  5L2Z L;  2YGO A;  1Z6C A;  1N7D A;  2J4I B;  4OTJ A;  1MQ6 L;  5JVZ A;  4JZE L;  1CEJ A;  2JJL A;  4X8T L;  3LTG D;  1CVU A;  3EXW A;  3CNC A;  3N8X A;  1PRH A;  1KKE A;  3MQE A;  2WG4 B;  1U8C B;  2VVV L;  3LC3 B;  4G1M B;  1KSN B;  2XBX L;  3TBD A;  2FZZ L;  4XLW A;  2W3I B;  2OYU P;  1YUK B;  2EI7 B;  2J2U B;  1EPI A;  4WYJ A;  4M10 A;  4XC5 A;  2FLR L;  4K6W A;  1LK9 A;  2VWM K;  5L30 L;  2HOX A;  2VVC K;  3Q7D A;  4ATZ A;  2W3K B;  3RR3 A;  3V64 C;  2BMG A;  5CKQ A;  1I0U A;  1IP0 A;  1G1S A;  1CVW L;  2WGT A;  1PGE A;  1CCV A;  3NTG A;  4NA9 L;  2BOU A;  2MGP A;  3LIW B;  3NT1 A;  4CW8 A;  5CKN A;  2DDU A;  3CS7 L;  3QND A;  5CIS A;  1DX5 I;  1JV2 B;  2VWO L;  3ZPE A;  2F9B L;  2WPJ E;  2W2M E;  1A3P A;  3POY A;  1IGX A;  2J2J A;  1NZI A;  3LN1 A;  4AQT A;  3TK5 B;  4BTT A;  2UWO B;  1K36 A;  4ZXX L;  3DEM A;  5FDQ A;  3HO5 A;  2P3T A;  3H5C B;  2OYE P;  1UXE A;  2RHP A;  3V65 B;  2PUQ L;  1N1I A;  3CA7 A;  4K6T A;  1WHF A;  2NPR A;  2P94 L;  5L2Y L;  2Q1J B;  2BOK L;  2P95 L;  2TGF A;  5JB9 E;  1XKB A;  1QHV A;  3MDL A;  2VWN L;  2VRS A;  2W86 A;  4ZAE B;  5KN5 C;  2J12 A;  1HCG B;  2J95 B;  3SOB B;  4BDX A;  1EBV A;  2WYJ B;  1ATE A;  2K2T A;  1CCF A;  4K6V A;  1IQK L;  5JVY A;  1PTH A;  2VWL L;  4A7I A;  1KLJ L;  2WBW A;  4E1G A;  1OB1 C;  1MQ5 L;  2WYG B;  5KIR A;  1HT5 A;  3EXV A;  1YGC L;  1CQE A;  4Z6A L;  3TH3 L;  2Y82 B;  1NFX B;  3N8Y A;  4LOR A;  3KRK A;  1F7M A;  3PGH A;  4YT6 L;  1C5M F;  5EGM B;  4X8V L;  2IUM A;  1IOE L;  1HZ8 A;  5F1A A;  1DQB A;  1HRE A;  3NTB A;  4XL8 A;  5IKQ A;  2I9A A;  2W2P E;  1M1X B;  2W2Q E;  2FLB L;  4JZF L;  1HT8 A;  1UZJ A;  1TPG A;  2I9B A;  3KQB L;  3QH0 A;  2BZ6 L;  3LC5 B;  1Q4G A;  2RA0 L;  1W8B L;  1DIY A;  1NFY B;  4OTY A;  3ZYI B;  1KAC A;  4BDW A;  2J94 B;  3QMO A;  1NT0 A;  5MHS A;  1XDT R;  4JYU L;  1APQ A;  4ZDG A;  4RRW A;  2KV4 A;  2VJ3 A;  1GK5 A;  1IQI L;  3N8Z A;  5COX A;  4RRZ A;  1DVA L;  3ZPF A;  3M36 L;  1O5D L;  2BT7 A;  2QLK A;  1F0R B;  2VH0 B;  1NQL B;  3O8E A;  2G00 L;  2P26 A;  3EOY A;  2VH6 B;  3KCG L;  1EPG A;  1L5G B;  2BOH A;  1LPZ A;  2BQW A;  1HAF A;  1H7Z A;  1LPK A;  2YGP A;  4K6U A;  3HS7 A;  2MGR A;  3KQD L;  3TK6 B;  3F1S B;  2H9E C;  2XBW L;  1U67 A;  3OLT A;  2Y7X B;  4YT7 L;  1FFM A;  1IQE L;  3U73 A;  5JBC E;  5CKM A;  5JBB E;  4MMZ B;  2Y81 B;  2WPL E;  4BTU A;  4LIY A;  1UZK A;  3KK6 A;  1PXX A;  4BXW A;  3N8V A;  4MMX B;  1JBU L;  2J38 B;  5E8D A;  1IGZ A;  3LTF B;  1IJQ A;  1HJ7 A;  2W9L C;  2FLG A;  3EGF A;  1NOB A;  2WGU A;  4XQB A;  3BPS E;  4Y7B B;  3N0I A;  1COU A;  2D1J B;  4O02 B;  3FBY A;  4O1Z A;  1FAK L;  2J34 B;  4MMY B;  3BT2 A;  2VTW A;  2PHB B;  1NFW B;  5JW1 A;  3KQE L;  4Y76 B;  4JZD L;  2W2N E;  1HAE A;  3N8Y B;  3N8W B;  5I46 L;  1F0S B;  4XBM A;  1HRF A;  2EI6 B;  2KNI A;  4ZHA B;  4RRX A;  1HX2 A;  3LAQ A;  2BT8 A;  2P93 L;  4ISI L;  1QFK L;  4X8S L;  5JB8 E;  1EGF A;  2BQ7 A;  4CSY A;  2W26 B;  1X7A L;  2W2O E;  1KIG L;  3Q3K B;  2MHP A;  2Y5H L;  4Z0L A;  3FFG L;  1IQH L;  4CUD A;  1W7X L;  1F7E A;  2M74 A;  1EMN A;  3TZI A;  1URK A;  2EI8 B;  4M11 A;  1SZB A;  4X8U L;  1EQH A;  1IQF L;  1V1H A;  1YUF A;  1UXB A;  3HPT A;  1LMJ A;  4Y6D B;  1G1Q A;  4ZH8 B;  3FCS B;  2BOX A;  1EZQ B;  4JYV L;  2WFX B;  2AYL A;  2WPK E;  1DDX A;  3HO3 A;  2HOR A;  3OLU A;  2B7D L;  3K9X A;  1ATB A;  4Y71 B;  1IQM L;  4XL1 A;  3KL6 B;  2UWL B;  2O39 A;  1ADX A;  3ZYJ B;  4D90 A;  3U7U G;  4XQA A;  2Y7Z B;  1V3X B;  1LQD A;  3M37 L;  1KLI L;  1XFE A;  1EPH A;  3LN0 A;  4NG9 L;  2Y38 A;  1IOX A;  3ZYG A;  4Y79 B;  1ATD A;  4RUT A;  2WFT A;  1JL9 A;  2BO2 A;  4ZXY L;  2BQ6 A;  3GCW E;  1FSB A;  3F0Y A;  2BZU A;  1IVO C;  4FM5 A;  1B9W A;  3KQC L;  4ODB A;  5IKR A;  2FD6 A;  3SW2 A;  1BF9 A;  3C9A C;  4TGF A;  1L3Y A;  2PR3 B;  2JKH L;  1EPJ A;  1G2L B;  1NFU B;  2P3F N;  4RRY A;  1UXA A;  1MOX C;  1V1I A;  2XC0 L;  4D0F A;  3BT1 A;  2P28 B;  1P0S L;  1UZP A;  2YGQ A;  4COX A;  3GCX E;  1CX2 A;  2BSF A;  1K37 A;  4CUF A;  2WPI E;  4YZU B;  2K2S B;  1APO A;  3QCW A;  5K0H B;  3L88 A;  3R05 A;  2WBV A;  2WG3 C;  3ELA L;  2VVU L;  2BZV A;  1QIU A;  2Y5F L;  4Y7A B;  3GIS X;  1KLO A;  1IQN L;  1EMO A;  2WST A;  2UWP B;  2Y80 B;  1YO8 A;  3ASI A;  3ENS A;  1XKA L;  1IQG L;  2XC4 L;  4A94 C;  3S6X A;  2XBV L;  1G1R A;  3L89 A;  1G2M B;  2P3U A;  3HS5 A;  3BQ4 A;  2H9E L;  1NPE B;  4CUE A;  1RFN B;  1TOZ A;  3HO4 A;  2P3F L;  1J9C L;  3IIT B;  2IUN A;  4D63 A;  1WU1 B;  1LMM A;  3SOQ A;  1PFX L;  1FF7 A;  3IJE B;  1EQG A;  2XBY L;  2OJ6 A;  1G1T A;  1AUT L;  4LMF A;  2GD4 A;  5F19 A;  3F6U L;  2KL7 A;  3NJP C;  3TGF A;  1IQL L;  3SOV A;  4ISH L;  4D0E A;  2Y5G L;  1YUG A;  5IKT A;  1LPG A;  1WHE A;  1P6A A;  2ADX A;  2RNL A;  1EAI C;  1FJS L;  2J1K C;  4GU4 A;  1UZQ A;  1FAX L;  1ATA A;  5IKV A;  3N8W A;  4D62 A;  2XC5 L;  2CJI B;  4Z0K B;  4PH9 A;  1ZAQ A;  2P16 L;  3P5B L;  4RS0 A;  4BXS A;  6COX A;  4GU3 A; 
#chains in the Genus database with same CATH homology
 4XC5 A;  2BT7 A;  2VRS A;  2OJ5 A;  4ODB A;  4GU4 A;  2BSF A;  3EOY A;  1QIU A;  1V1I A;  2BT8 A;  5MHS A;  1KKE A;  3S6X A;  1V1H A;  2JJL A;  4GU3 A;  2OJ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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