4GU4A

Crystal structure of the t1l reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
205
structure length
205
Chain Sequence
KIDSVLPPLTVREASGVRTLSFGYDTSDFTIINSVLSLRSRLTLPTYRYPLELDTANNRVQVADRFGMRTGTWTGQLQYQHPQLSWRANVTLNLMKVDDWLVLSFSQMTTNSIMADGKFVINFVSGLSSGWQTGDTEPSSTIDPLSTTFAAVQFLNNGQRIDAFRIMGVSEWTDGELEIKNYGGTYTGHTQVYWAPWTIMYPCNV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus.
pubmed doi rcsb
molecule tags Viral protein
source organism Mammalian orthoreovirus 1
molecule keywords Outer capsid protein sigma-1
total genus 30
structure length 205
sequence length 205
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.20 Mainly Beta Ribbon Laminin reovirus attachment protein sigma1; domain 1 4gu4A01
2.60.90.20 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Virus attachment protein , globular domain 4gu4A02
2VRSA 1KKEA 3S6XA 4GU3A 4ODBA 1V1IA 2JJLA 2OJ6A 3EOYA 2BSFA 1V1HA 5MHSA 4GU4A 2BT7A 2OJ5A 1QIUA 2BT8A 4XC5A
chains in the Genus database with same CATH superfamily
5I46L 1YUKB 2VTWA 1ATDA 2XC0L 4YZUB 1NPEB 1CX2A 3GISX 4Z6AL 3EOYA 5F1AA 2J1KC 4OTJA 1TOZA 3CA7A 3N8WA 1V3XB 3KQDL 1PTHA 3SOBB 1PRHA 5CKNA 2I9BA 2J34B 1EGFA 1YO8A 2IUNA 2WGTA 5JBBE 2JJLA 2Y80B 1EMOA 1URKA 3HO3A 1MOXC 4RUTA 1TLEA 5COXA 3TGFA 1HJ7A 2KNIA 2W9LC 1F7EA 4BXSA 2J12A 1HREA 4FM5A 2YGQA 3HO5A 3NTGA 4E1GA 2I9AA 2P3FN 2Y7XB 3HS5A 1FE2A 4D0EA 3QH0A 1KACA 4LORA 2W26B 2P28B 1GK5A 2K2SB 1DX5I 4Y7BB 5CISA 1HX2A 2WFXB 1L3YA 4Y7AB 3V65B 1NFUB 4ZH8B 4WYJA 1KIGL 3S6XA 2M74A 2UWOB 2VWOL 4JZFL 3QMOA 4Y71B 4K6VA 2PHBB 5IKTA 3U7UG 3SW2A 3QNDA 3FCSB 2P3FL 3PGHA 1WHEA 5E8DA 1W7XL 3IJEB 3F1SB 3BPSE 4GU4A 2P3UA 4NA9L 1HT8A 4A7IA 2WYGB 2Y5FL 3BQ4A 2BOHA 4CSYA 3L89A 1QIUA 3EGFA 3LAQA 2J95B 4TGFA 1RFNB 3L88A 2J94B 2W3IB 1HZ8A 3M37L 2BT7A 2WFTA 4JYVL 4ISHL 1HAEA 4X8SL 4BTIA 2WGUA 3N8XA 4X8UL 4RRWA 4XL1A 4Y76B 4RRZA 3F6UL 3N8ZA 1IQGL 1KNBA 1LMJA 2K2TA 4G1MB 2H9EC 3ZPEA 1FAXL 4RRYA 1HAFA 2WPIE 4BDWA 3FBYA 3HS7A 1IGZA 3HS6A 2MGPA 4JZEL 1PGEA 3H5CB 1UZKA 3GCXE 3GCWE 1XDTR 2NPRA 4NGAL 2OJ6A 3HPTA 4ZXXL 1IQML 3N8YB 1HRFA 2VH6B 3KCGL 1Z6CA 2W86A 1IOXA 2O39A 1V1HA 3ZPFA 1EZQB 1BF9A 2VVCK 3TBDA 2WPHE 3SOQA 1FFMA 3OLUA 5JB9E 1NOBA 2WPME 1SZBA 1YUFA 4RRXA 2D1JB 4M10A 4C16A 3F0YA 1P9JA 2BZ6L 1KLJL 1AUTL 1MQ6L 2PUQL 1PFXL 3ZYGA 1F0RB 1P6AA 3K9XA 6COXA 4ISIL 3TK6B 1G1SA 2BSFA 2XC5L 3KQCL 1LMMA 1PXXA 2VVUL 1KLIL 1NFXB 4PH9A 4Y6DB 1J9CL 4ZHAB 4OTYA 3V64C 1IVOC 1HT5A 1APQA 1P0SL 2WPKE 1APOA 2VWMK 4NG9L 4A94C 2AYLA 3ELAL 1EQGA 4BTTA 2EI8B 4YT7L 2XBWL 2BQ7A 3MQEA 3ZYJB 4ZAEB 1IQJL 1ADXA 2P95L 4D90A 4GU3A 3LIWB 1U67A 2BOXA 1LPGA 1P69A 2VRSA 2WG4B 5IKRA 2CJIB 1UXEA 3N0IA 2J38B 3ENSA 1K37A 1IQLL 4Z0LA 2BZUA 1X7AL 1NFYB 4X8TL 3RR3A 3POYA 2FLGA 4Y79B 4JZDL 3OLTA 1XKAL 1IQFL 1G1RA 1ATEA 4AQTA 1OB1C 1I0UA 2J2JA 2HORA 1L5GB 5L30L 2W2OE 1IQHL 1JV2B 3EXVA 3NTBA 3BT1A 2WPLE 2UWLB 1EQHA 1M1XB 4K6TA 3LC5B 2P16L 3TK5B 5KN5C 1CEJA 4ZXYL 1IQEL 1KSNB 3IITB 1XFEA 2J2UB 5CKQA 5IKVA 2IUMA 1G2MB 1KKEA 3LTGD 2Y5GL 4CUFA 4XQAA 2J4IB 2YGPA 4COXA 4RS0A 4LMFA 2XBXL 4X8VL 4D0FA 2FZZL 1NT0A 3R05A 1UXBA 4XBMA 2EI7B 2FLBL 3U73A 2BMGA 3KQEL 3NT1A 1LPZA 2BT8A 1IQNL 5L2ZL 2MHPA 3EXWA 3N8WB 3LTFB 2WBVA 2BQWA 4O02B 1G1TA 2G00L 4MMYB 1JL9A 3BT2A 2OYUP 1H7ZA 4K6WA 1WHFA 2WG3C 2PR3B 1O5DL 3O8EA 1EPJA 2B7DL 1IGXA 2YGOA 2BOKL 2HOXA 2W2NE 4MMXB 4BDXA 3P5BL 1EBVA 1HCGB 4O1ZA 1FAKL 1DIYA 2Y81B 4Z0KB 1IQKL 1F0SB 3LN0A 3QCWA 3KK6A 4YT6L 2Y82B 2BZVA 4ODBA 3LC3B 3N8YA 5CKMA 1NZIA 1DDXA 3NJPC 2W2QE 1F7MA 2FLRL 2VH0B 2VWLL 5KIRA 3TZIA 4D62A 2KV4A 5IKQA 4XLWA 3CNCA 1QHVA 2MGRA 3KRKA 1NFWB 1COUA 2VJ3A 2WSTA 1ATAA 1QFKL 1V1IA 2FD6A 1Z6EL 2Q1JB 3KQBL 1U8CB 1G2LB 3TH3L 1EMNA 4ZDGA 1UZPA 4CUEA 2W2PE 5L2YL 2Y5HL 2WBWA 2BO2A 1WU1B 4XL8A 3CFWA 1CCVA 4D63A 3MDLA 1N7DA 1W8BL 1ZAQA 5JBCE 3FFGL 3KL6B 3CENL 1IQIL 1CQEA 2BOUA 2WZPP 3C9AC 2JKHL 2OJ5A 1A3PA 1FF7A 4ATZA 4JYUL 1C5MF 1B9WA 2RHPA 1MQ5L 4BTUA 5FDQA 5JW1A 1ATBA 3Q3KB 2P93L 1EPGA 2ADXA 2TGFA 2QLKA 2W2ME 4M11A 3HO4A 1XKBA 2VVVL 1LQDA 1DQBA 2Y38A 3M36L 2RNLA 1DVAL 1CVUA 4LIYA 5MHSA 1EPIA 1FSBA 2BQ6A 1IJQA 5K0HB 2F9BL 2KL7A 3N8VA 1JBUL 3CS7L 2Y7ZB 5JVYA 4K6UA 1K36A 1N1IA 1CCFA 2KB9A 4MMZB 4BXWA 5F19A 1Q4GA 1TPGA 3DEMA 5EGMB 3SOVA 3ASIA 2P3TA 5JB8E 1FJSL 2OYEP 4XQBA 1EPHA 2RA0L 2VWNL 5JBAE 1EAIC 1LK9A 3ZYIB 4CW8A 2P94L 2W3KB 1YUGA 2EI6B 2WPJE 2P26A 2XBVL 4CUDA 2UWPB 1YGCL 2H9EL 1LPKA 1NQLB 2WYJB 2GD4A 1IOEL 1G1QA 1UZQA 3LN1A 2XBYL 2XC4L 1KLOA 2DDUA 3Q7DA 1IP0A 1UXAA 1CVWL 5JVZA 1UZJA 4XC5A
chains in the Genus database with same CATH topology
2VRSA 1KKEA 3S6XA 4GU3A 4ODBA 1V1IA 2JJLA 2OJ6A 3EOYA 2BSFA 1V1HA 5MHSA 4GU4A 2BT7A 2OJ5A 1QIUA 2BT8A 4XC5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VRS A;  1KKE A;  3S6X A;  4GU3 A;  4ODB A;  1V1I A;  2JJL A;  2OJ6 A;  3EOY A;  2BSF A;  1V1H A;  5MHS A;  4GU4 A;  2BT7 A;  2OJ5 A;  1QIU A;  2BT8 A;  4XC5 A; 
#chains in the Genus database with same CATH topology
 5I46 L;  1YUK B;  2VTW A;  1ATD A;  2XC0 L;  4YZU B;  1NPE B;  1CX2 A;  3GIS X;  4Z6A L;  3EOY A;  5F1A A;  2J1K C;  4OTJ A;  1TOZ A;  3CA7 A;  3N8W A;  1V3X B;  3KQD L;  1PTH A;  3SOB B;  1PRH A;  5CKN A;  2I9B A;  2J34 B;  1EGF A;  1YO8 A;  2IUN A;  2WGT A;  5JBB E;  2JJL A;  2Y80 B;  1EMO A;  1URK A;  3HO3 A;  1MOX C;  4RUT A;  1TLE A;  5COX A;  3TGF A;  1HJ7 A;  2KNI A;  2W9L C;  1F7E A;  4BXS A;  2J12 A;  1HRE A;  4FM5 A;  2YGQ A;  3HO5 A;  3NTG A;  4E1G A;  2I9A A;  2P3F N;  2Y7X B;  3HS5 A;  1FE2 A;  4D0E A;  3QH0 A;  1KAC A;  4LOR A;  2W26 B;  2P28 B;  1GK5 A;  2K2S B;  1DX5 I;  4Y7B B;  5CIS A;  1HX2 A;  2WFX B;  1L3Y A;  4Y7A B;  3V65 B;  1NFU B;  4ZH8 B;  4WYJ A;  1KIG L;  3S6X A;  2M74 A;  2UWO B;  2VWO L;  4JZF L;  3QMO A;  4Y71 B;  4K6V A;  2PHB B;  5IKT A;  3U7U G;  3SW2 A;  3QND A;  3FCS B;  2P3F L;  3PGH A;  1WHE A;  5E8D A;  1W7X L;  3IJE B;  3F1S B;  3BPS E;  4GU4 A;  2P3U A;  4NA9 L;  1HT8 A;  4A7I A;  2WYG B;  2Y5F L;  3BQ4 A;  2BOH A;  4CSY A;  3L89 A;  1QIU A;  3EGF A;  3LAQ A;  2J95 B;  4TGF A;  1RFN B;  3L88 A;  2J94 B;  2W3I B;  1HZ8 A;  3M37 L;  2BT7 A;  2WFT A;  4JYV L;  4ISH L;  1HAE A;  4X8S L;  4BTI A;  2WGU A;  3N8X A;  4X8U L;  4RRW A;  4XL1 A;  4Y76 B;  4RRZ A;  3F6U L;  3N8Z A;  1IQG L;  1KNB A;  1LMJ A;  2K2T A;  4G1M B;  2H9E C;  3ZPE A;  1FAX L;  4RRY A;  1HAF A;  2WPI E;  4BDW A;  3FBY A;  3HS7 A;  1IGZ A;  3HS6 A;  2MGP A;  4JZE L;  1PGE A;  3H5C B;  1UZK A;  3GCX E;  3GCW E;  1XDT R;  2NPR A;  4NGA L;  2OJ6 A;  3HPT A;  4ZXX L;  1IQM L;  3N8Y B;  1HRF A;  2VH6 B;  3KCG L;  1Z6C A;  2W86 A;  1IOX A;  2O39 A;  1V1H A;  3ZPF A;  1EZQ B;  1BF9 A;  2VVC K;  3TBD A;  2WPH E;  3SOQ A;  1FFM A;  3OLU A;  5JB9 E;  1NOB A;  2WPM E;  1SZB A;  1YUF A;  4RRX A;  2D1J B;  4M10 A;  4C16 A;  3F0Y A;  1P9J A;  2BZ6 L;  1KLJ L;  1AUT L;  1MQ6 L;  2PUQ L;  1PFX L;  3ZYG A;  1F0R B;  1P6A A;  3K9X A;  6COX A;  4ISI L;  3TK6 B;  1G1S A;  2BSF A;  2XC5 L;  3KQC L;  1LMM A;  1PXX A;  2VVU L;  1KLI L;  1NFX B;  4PH9 A;  4Y6D B;  1J9C L;  4ZHA B;  4OTY A;  3V64 C;  1IVO C;  1HT5 A;  1APQ A;  1P0S L;  2WPK E;  1APO A;  2VWM K;  4NG9 L;  4A94 C;  2AYL A;  3ELA L;  1EQG A;  4BTT A;  2EI8 B;  4YT7 L;  2XBW L;  2BQ7 A;  3MQE A;  3ZYJ B;  4ZAE B;  1IQJ L;  1ADX A;  2P95 L;  4D90 A;  4GU3 A;  3LIW B;  1U67 A;  2BOX A;  1LPG A;  1P69 A;  2VRS A;  2WG4 B;  5IKR A;  2CJI B;  1UXE A;  3N0I A;  2J38 B;  3ENS A;  1K37 A;  1IQL L;  4Z0L A;  2BZU A;  1X7A L;  1NFY B;  4X8T L;  3RR3 A;  3POY A;  2FLG A;  4Y79 B;  4JZD L;  3OLT A;  1XKA L;  1IQF L;  1G1R A;  1ATE A;  4AQT A;  1OB1 C;  1I0U A;  2J2J A;  2HOR A;  1L5G B;  5L30 L;  2W2O E;  1IQH L;  1JV2 B;  3EXV A;  3NTB A;  3BT1 A;  2WPL E;  2UWL B;  1EQH A;  1M1X B;  4K6T A;  3LC5 B;  2P16 L;  3TK5 B;  5KN5 C;  1CEJ A;  4ZXY L;  1IQE L;  1KSN B;  3IIT B;  1XFE A;  2J2U B;  5CKQ A;  5IKV A;  2IUM A;  1G2M B;  1KKE A;  3LTG D;  2Y5G L;  4CUF A;  4XQA A;  2J4I B;  2YGP A;  4COX A;  4RS0 A;  4LMF A;  2XBX L;  4X8V L;  4D0F A;  2FZZ L;  1NT0 A;  3R05 A;  1UXB A;  4XBM A;  2EI7 B;  2FLB L;  3U73 A;  2BMG A;  3KQE L;  3NT1 A;  1LPZ A;  2BT8 A;  1IQN L;  5L2Z L;  2MHP A;  3EXW A;  3N8W B;  3LTF B;  2WBV A;  2BQW A;  4O02 B;  1G1T A;  2G00 L;  4MMY B;  1JL9 A;  3BT2 A;  2OYU P;  1H7Z A;  4K6W A;  1WHF A;  2WG3 C;  2PR3 B;  1O5D L;  3O8E A;  1EPJ A;  2B7D L;  1IGX A;  2YGO A;  2BOK L;  2HOX A;  2W2N E;  4MMX B;  4BDX A;  3P5B L;  1EBV A;  1HCG B;  4O1Z A;  1FAK L;  1DIY A;  2Y81 B;  4Z0K B;  1IQK L;  1F0S B;  3LN0 A;  3QCW A;  3KK6 A;  4YT6 L;  2Y82 B;  2BZV A;  4ODB A;  3LC3 B;  3N8Y A;  5CKM A;  1NZI A;  1DDX A;  3NJP C;  2W2Q E;  1F7M A;  2FLR L;  2VH0 B;  2VWL L;  5KIR A;  3TZI A;  4D62 A;  2KV4 A;  5IKQ A;  4XLW A;  3CNC A;  1QHV A;  2MGR A;  3KRK A;  1NFW B;  1COU A;  2VJ3 A;  2WST A;  1ATA A;  1QFK L;  1V1I A;  2FD6 A;  1Z6E L;  2Q1J B;  3KQB L;  1U8C B;  1G2L B;  3TH3 L;  1EMN A;  4ZDG A;  1UZP A;  4CUE A;  2W2P E;  5L2Y L;  2Y5H L;  2WBW A;  2BO2 A;  1WU1 B;  4XL8 A;  3CFW A;  1CCV A;  4D63 A;  3MDL A;  1N7D A;  1W8B L;  1ZAQ A;  5JBC E;  3FFG L;  3KL6 B;  3CEN L;  1IQI L;  1CQE A;  2BOU A;  2WZP P;  3C9A C;  2JKH L;  2OJ5 A;  1A3P A;  1FF7 A;  4ATZ A;  4JYU L;  1C5M F;  1B9W A;  2RHP A;  1MQ5 L;  4BTU A;  5FDQ A;  5JW1 A;  1ATB A;  3Q3K B;  2P93 L;  1EPG A;  2ADX A;  2TGF A;  2QLK A;  2W2M E;  4M11 A;  3HO4 A;  1XKB A;  2VVV L;  1LQD A;  1DQB A;  2Y38 A;  3M36 L;  2RNL A;  1DVA L;  1CVU A;  4LIY A;  5MHS A;  1EPI A;  1FSB A;  2BQ6 A;  1IJQ A;  5K0H B;  2F9B L;  2KL7 A;  3N8V A;  1JBU L;  3CS7 L;  2Y7Z B;  5JVY A;  4K6U A;  1K36 A;  1N1I A;  1CCF A;  2KB9 A;  4MMZ B;  4BXW A;  5F19 A;  1Q4G A;  1TPG A;  3DEM A;  5EGM B;  3SOV A;  3ASI A;  2P3T A;  5JB8 E;  1FJS L;  2OYE P;  4XQB A;  1EPH A;  2RA0 L;  2VWN L;  5JBA E;  1EAI C;  1LK9 A;  3ZYI B;  4CW8 A;  2P94 L;  2W3K B;  1YUG A;  2EI6 B;  2WPJ E;  2P26 A;  2XBV L;  4CUD A;  2UWP B;  1YGC L;  2H9E L;  1LPK A;  1NQL B;  2WYJ B;  2GD4 A;  1IOE L;  1G1Q A;  1UZQ A;  3LN1 A;  2XBY L;  2XC4 L;  1KLO A;  2DDU A;  3Q7D A;  1IP0 A;  1UXA A;  1CVW L;  5JVZ A;  1UZJ A;  4XC5 A; 
#chains in the Genus database with same CATH homology
 2VRS A;  1KKE A;  3S6X A;  4GU3 A;  4ODB A;  1V1I A;  2JJL A;  2OJ6 A;  3EOY A;  2BSF A;  1V1H A;  5MHS A;  4GU4 A;  2BT7 A;  2OJ5 A;  1QIU A;  2BT8 A;  4XC5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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