1B8FA

Histidine ammonia-lyase (hal) from pseudomonas putida
Total Genus 195
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
195
sequence length
507
structure length
506
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Lyase
molecule keywords Histidine ammonia-lyase
publication title Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile.
pubmed doi rcsb
source organism Pseudomonas putida
total genus 195
structure length 506
sequence length 507
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 1999-01-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1b8fA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1b8fA02
4ADLA 4C5UA 4V2RA 4C5SA 4ADMA 3CZOA 2FUSA 2NYFA 1AUWA 1RE5A 2E9FA 2PTSA 3BHGA 1TJ7A 3RRPA 5HW2A 1KQ7A 3KDYA 3OCFA 3R6VA 1K62A 4C5RA 1HY1A 1TJVA 1HY0A 2RJSA 2PTRA 3NO9A 2O78A 4APAA 4HGVA 2J91A 1TJUA 2PFMA 4C6GA 1B8FA 1GK2A 1J3UA 1YFMA 3OCEA 1YFEA 5EYTA 5D6BA 2RJRA 4BABA 4NLEA 1C3CA 2YIIA 1FUPA 4MX2A 1FUQA 1XWOA 4FLCA 2O7EA 3R6YA 1U16A 3NZ4A 1C3UA 2VD6A 1GK3A 5F92A 1FURA 4EEIA 1W27A 3E04A 2HVGA 3UNVA 1JSWA 1DOFA 2O7DA 2QGAB 2NYNA 1T6PA 1FUOA 3TV2A 1GKMA 2O7BA 3C8TA 5F91A 4CQ5A 1GKJA 4FFXA 2PTQA 1I0AA 1DCNA 3GTDA 2X75A 1T6JA 1Q5NA 3KDZA 2QVEA 3GZHA 4V2QA 1TJWA 3QBPA 1Y2MA 2O7FA 3R6QA 2O6YA 1U15A 3RD8A 4APBA 4BAAA 5EYVA 4NSLA 4EFCA 1VDKA 1EB4A 2OHYA 1K7WA 1YISA
chains in the Genus database with same CATH superfamily
4ADLA 4C5UA 5M0JA 4V2RA 4C5SA 4ADMA 3CZOA 2FUSA 2NYFA 1AUWA 1RE5A 2E9FA 2PTSA 3BHGA 1TJ7A 3RRPA 5HW2A 2FENA 1KQ7A 3KDYA 3OCFA 3R6VA 4WNLA 1K62A 4C5RA 1HY1A 1TJVA 1HY0A 2RJSA 2PTRA 3NO9A 2O78A 4APAA 4HGVA 2J91A 1TJUA 2PFMA 4C6GA 1B8FA 1GK2A 1J3UA 3CRVA 1YFMA 3OCEA 1YFEA 3CRW1 5EYTA 5D6BA 2RJRA 4BABA 4NLEA 1C3CA 1XLYA 5M0IA 2YIIA 1FUPA 4MX2A 1FUQA 1XWOA 4FLCA 2O7EA 3R6YA 1U16A 3NZ4A 1C3UA 2VD6A 1GK3A 5F92A 1FURA 4EEIA 1W27A 3E04A 2HVGA 3UNVA 1JSWA 1DOFA 2O7DA 2QGAB 2NYNA 2VSFA 1T6PA 1FUOA 1XL7A 3TV2A 1GKMA 2O7BA 3C8TA 5F91A 4CQ5A 1GKJA 4FFXA 2PTQA 1I0AA 1DCNA 3GTDA 2X75A 4A15A 1XL8A 2VL7A 1T6JA 5H8WA 1Q5NA 2QVEA 3KDZA 3GZHA 4V2QA 1TJWA 3QBPA 1Y2MA 2FELA 2O7FA 3R6QA 2O6YA 1XMCA 1U15A 3RD8A 4APBA 4BAAA 1XMDA 5EYVA 4NSLA 4EFCA 1VDKA 1EB4A 2OHYA 1K7WA 1YISA
chains in the Genus database with same CATH topology
4ADLA 4C5UA 4V2RA 4C5SA 4ADMA 3CZOA 2FUSA 2NYFA 1AUWA 1RE5A 2E9FA 2PTSA 3BHGA 1TJ7A 3RRPA 5HW2A 1KQ7A 3KDYA 3OCFA 3R6VA 1K62A 4C5RA 1HY1A 1TJVA 1HY0A 2RJSA 2PTRA 3NO9A 2O78A 4APAA 4HGVA 2J91A 1TJUA 2PFMA 4C6GA 1B8FA 1GK2A 1J3UA 1YFMA 3OCEA 1YFEA 5EYTA 5D6BA 2RJRA 4BABA 4NLEA 1C3CA 2YIIA 1FUPA 4MX2A 1FUQA 1XWOA 4FLCA 2O7EA 3R6YA 1U16A 3NZ4A 1C3UA 2VD6A 1GK3A 5F92A 1FURA 4EEIA 1W27A 3E04A 2HVGA 3UNVA 1JSWA 1DOFA 2O7DA 2QGAB 2NYNA 1T6PA 1FUOA 3TV2A 1GKMA 2O7BA 3C8TA 5F91A 4CQ5A 1GKJA 4FFXA 2PTQA 1I0AA 1DCNA 3GTDA 2X75A 1T6JA 1Q5NA 3KDZA 2QVEA 3GZHA 4V2QA 1TJWA 3QBPA 1Y2MA 2O7FA 3R6QA 2O6YA 1U15A 3RD8A 4APBA 4BAAA 5EYVA 4NSLA 4EFCA 1VDKA 1EB4A 2OHYA 1K7WA 1YISA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ADL A;  4C5U A;  4V2R A;  4C5S A;  4ADM A;  3CZO A;  2FUS A;  2NYF A;  1AUW A;  1RE5 A;  2E9F A;  2PTS A;  3BHG A;  1TJ7 A;  3RRP A;  5HW2 A;  1KQ7 A;  3KDY A;  3OCF A;  3R6V A;  1K62 A;  4C5R A;  1HY1 A;  1TJV A;  1HY0 A;  2RJS A;  2PTR A;  3NO9 A;  2O78 A;  4APA A;  4HGV A;  2J91 A;  1TJU A;  2PFM A;  4C6G A;  1B8F A;  1GK2 A;  1J3U A;  1YFM A;  3OCE A;  1YFE A;  5EYT A;  5D6B A;  2RJR A;  4BAB A;  4NLE A;  1C3C A;  2YII A;  1FUP A;  4MX2 A;  1FUQ A;  1XWO A;  4FLC A;  2O7E A;  3R6Y A;  1U16 A;  3NZ4 A;  1C3U A;  2VD6 A;  1GK3 A;  5F92 A;  1FUR A;  4EEI A;  1W27 A;  3E04 A;  2HVG A;  3UNV A;  1JSW A;  1DOF A;  2O7D A;  2QGA B;  2NYN A;  1T6P A;  1FUO A;  3TV2 A;  1GKM A;  2O7B A;  3C8T A;  5F91 A;  4CQ5 A;  1GKJ A;  4FFX A;  2PTQ A;  1I0A A;  1DCN A;  3GTD A;  2X75 A;  1T6J A;  1Q5N A;  3KDZ A;  2QVE A;  3GZH A;  4V2Q A;  1TJW A;  3QBP A;  1Y2M A;  2O7F A;  3R6Q A;  2O6Y A;  1U15 A;  3RD8 A;  4APB A;  4BAA A;  5EYV A;  4NSL A;  4EFC A;  1VDK A;  1EB4 A;  2OHY A;  1K7W A;  1YIS A; 
#chains in the Genus database with same CATH topology
 4ADL A;  4C5U A;  5M0J A;  4V2R A;  4C5S A;  4ADM A;  3CZO A;  2FUS A;  2NYF A;  1AUW A;  1RE5 A;  2E9F A;  2PTS A;  3BHG A;  1TJ7 A;  3RRP A;  5HW2 A;  2FEN A;  1KQ7 A;  3KDY A;  3OCF A;  3R6V A;  4WNL A;  1K62 A;  4C5R A;  1HY1 A;  1TJV A;  1HY0 A;  2RJS A;  2PTR A;  3NO9 A;  2O78 A;  4APA A;  4HGV A;  2J91 A;  1TJU A;  2PFM A;  4C6G A;  1B8F A;  1GK2 A;  1J3U A;  3CRV A;  1YFM A;  3OCE A;  1YFE A;  3CRW 1;  5EYT A;  5D6B A;  2RJR A;  4BAB A;  4NLE A;  1C3C A;  1XLY A;  5M0I A;  2YII A;  1FUP A;  4MX2 A;  1FUQ A;  1XWO A;  4FLC A;  2O7E A;  3R6Y A;  1U16 A;  3NZ4 A;  1C3U A;  2VD6 A;  1GK3 A;  5F92 A;  1FUR A;  4EEI A;  1W27 A;  3E04 A;  2HVG A;  3UNV A;  1JSW A;  1DOF A;  2O7D A;  2QGA B;  2NYN A;  2VSF A;  1T6P A;  1FUO A;  1XL7 A;  3TV2 A;  1GKM A;  2O7B A;  3C8T A;  5F91 A;  4CQ5 A;  1GKJ A;  4FFX A;  2PTQ A;  1I0A A;  1DCN A;  3GTD A;  2X75 A;  4A15 A;  1XL8 A;  2VL7 A;  1T6J A;  5H8W A;  1Q5N A;  2QVE A;  3KDZ A;  3GZH A;  4V2Q A;  1TJW A;  3QBP A;  1Y2M A;  2FEL A;  2O7F A;  3R6Q A;  2O6Y A;  1XMC A;  1U15 A;  3RD8 A;  4APB A;  4BAA A;  1XMD A;  5EYV A;  4NSL A;  4EFC A;  1VDK A;  1EB4 A;  2OHY A;  1K7W A;  1YIS A; 
#chains in the Genus database with same CATH homology
 4ADL A;  4C5U A;  4V2R A;  4C5S A;  4ADM A;  3CZO A;  2FUS A;  2NYF A;  1AUW A;  1RE5 A;  2E9F A;  2PTS A;  3BHG A;  1TJ7 A;  3RRP A;  5HW2 A;  1KQ7 A;  3KDY A;  3OCF A;  3R6V A;  1K62 A;  4C5R A;  1HY1 A;  1TJV A;  1HY0 A;  2RJS A;  2PTR A;  3NO9 A;  2O78 A;  4APA A;  4HGV A;  2J91 A;  1TJU A;  2PFM A;  4C6G A;  1B8F A;  1GK2 A;  1J3U A;  1YFM A;  3OCE A;  1YFE A;  5EYT A;  5D6B A;  2RJR A;  4BAB A;  4NLE A;  1C3C A;  2YII A;  1FUP A;  4MX2 A;  1FUQ A;  1XWO A;  4FLC A;  2O7E A;  3R6Y A;  1U16 A;  3NZ4 A;  1C3U A;  2VD6 A;  1GK3 A;  5F92 A;  1FUR A;  4EEI A;  1W27 A;  3E04 A;  2HVG A;  3UNV A;  1JSW A;  1DOF A;  2O7D A;  2QGA B;  2NYN A;  1T6P A;  1FUO A;  3TV2 A;  1GKM A;  2O7B A;  3C8T A;  5F91 A;  4CQ5 A;  1GKJ A;  4FFX A;  2PTQ A;  1I0A A;  1DCN A;  3GTD A;  2X75 A;  1T6J A;  1Q5N A;  3KDZ A;  2QVE A;  3GZH A;  4V2Q A;  1TJW A;  3QBP A;  1Y2M A;  2O7F A;  3R6Q A;  2O6Y A;  1U15 A;  3RD8 A;  4APB A;  4BAA A;  5EYV A;  4NSL A;  4EFC A;  1VDK A;  1EB4 A;  2OHY A;  1K7W A;  1YIS A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...