4EEIA

Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with amp and succinate
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
433
structure length
414
Chain Sequence
MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRARAQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYEGFKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAYLSSFYLHFLVANTPFMREDCYKIVQQVESFSKKLQKVMHDEHNIILDIPEMDFEGIKKTYLKEIDHVFDRSVKAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
rcsb
source organism Francisella tularensis subsp. tularensis schu s4
molecule tags Lyase
molecule keywords Adenylosuccinate lyase
total genus 166
structure length 414
sequence length 433
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2012-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4eeiA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4eeiA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4eeiA02
1U15A 5EYVA 3CZOA 1YFMA 1Q5NA 1B8FA 1EB4A 1FUQA 3OCEA 3NZ4A 3KDYA 1HY0A 2YIIA 1C3UA 5EYTA 1FUPA 3RRPA 4FFXA 3TV2A 2J91A 2RJSA 2E9FA 4C5UA 3E04A 2PTSA 3GTDA 4V2RA 1DOFA 3C8TA 4APAA 1Y2MA 4HGVA 4CQ5A 3QBPA 4APBA 4C5SA 1K62A 2VD6A 1TJVA 2QVEA 1U16A 1K7WA 2NYFA 5HW2A 1TJ7A 4BAAA 1YFEA 3KDZA 4C6GA 3R6QA 1FUOA 5D6BA 2O7EA 2HVGA 2O7BA 3BHGA 1GKMA 2RJRA 2FUSA 1FURA 2O6YA 2PTQA 4ADLA 4MX2A 4EFCA 1GKJA 3R6YA 3R6VA 1J3UA 1GK3A 1DCNA 1TJUA 2O78A 2O7FA 2PTRA 2QGAB 1HY1A 3UNVA 1YISA 4EEIA 3OCFA 4C5RA 3GZHA 1XWOA 1T6JA 4NLEA 1W27A 4FLCA 1C3CA 2NYNA 3RD8A 4BABA 1JSWA 5F91A 1GK2A 1T6PA 3NO9A 1I0AA 4ADMA 2PFMA 4V2QA 2OHYA 1RE5A 1AUWA 1TJWA 2O7DA 2X75A 1KQ7A 1VDKA 5F92A 4NSLA
chains in the Genus database with same CATH superfamily
2FENA 1U15A 5EYVA 3CZOA 1YFMA 1Q5NA 4MUMA 1Z4PX 1B8FA 1EB4A 5M0JA 1FUQA 3OCEA 3NZ4A 4WNLA 3KDYA 1HY0A 3F4RA 3F4TA 1C3UA 2YIIA 5EYTA 1FUPA 3RRPA 4FFXA 3TV2A 2J91A 2RJSA 2VSFA 1IW7D 2E9FA 4C5UA 1Q91A 3E04A 2PTSA 3GTDA 4V2RA 1DOFA 3C8TA 4APAA 2D28C 1Y2MA 4HGVA 1U0LA 2FELA 2D27A 4CQ5A 3QBPA 4NFLA 4APBA 1K62A 2VD6A 3CRVA 4C5SA 2JAOA 1TJVA 2QVEA 1U16A 4L6CA 1K7WA 2NYFA 5HW2A 1TJ7A 3CRW1 4BAAA 1YFEA 3KDZA 2I7DA 4C6GA 3R6QA 1FUOA 5D6BA 2O7EA 2HVGA 3BWVA 4A15A 2O7BA 4YIHA 1Z4JA 4MWOA 3BHGA 2JAUA 1GKMA 2RJRA 2FUSA 1FURA 4L57A 2O6YA 2PTQA 1XL7A 4ADLA 3CI0K 4MX2A 4EFCA 1GKJA 3R6YA 3F4SA 1J3UA 3R6VA 1XMCA 1GK3A 1DCNA 1TJUA 2JAWA 2O78A 1MH9A 2O7FA 2VL7A 1Z4IA 2PTRA 2QGAB 2YV5A 1HY1A 3UNVA 1YISA 4EEIA 1Z4KA 4YIKA 3OCFA 2RCNA 4C5RA 3GZHA 1XWOA 1T6JA 4NLEA 1W27A 4FLCA 1C3CA 2NYNA 3RD8A 2JARA 4BABA 1JSWA 1T9HA 5F91A 1GK2A 1T6PA 3NO9A 1XMDA 1I0AA 4L6AA 1Z4QA 4ADMA 2PFMA 4V2QA 2OHYA 1Q92A 1RE5A 3U13A 1AUWA 1Z4MA 1TJWA 2O7DA 3U19A 4E88A 5M0IA 1Z4LA 2X75A 1KQ7A 1VDKA 1XL8A 5F92A 4IQJM 1XLYA 4NSLA 5H8WA
chains in the Genus database with same CATH topology
1U15A 5EYVA 3CZOA 1YFMA 1Q5NA 1B8FA 1EB4A 1FUQA 3OCEA 3NZ4A 3KDYA 1HY0A 2YIIA 1C3UA 5EYTA 1FUPA 3RRPA 4FFXA 3TV2A 2J91A 2RJSA 2E9FA 4C5UA 3E04A 2PTSA 3GTDA 4V2RA 1DOFA 3C8TA 4APAA 1Y2MA 4HGVA 4CQ5A 3QBPA 4APBA 4C5SA 1K62A 2VD6A 1TJVA 2QVEA 1U16A 1K7WA 2NYFA 5HW2A 1TJ7A 4BAAA 1YFEA 3KDZA 4C6GA 3R6QA 1FUOA 5D6BA 2O7EA 2HVGA 2O7BA 3BHGA 1GKMA 2RJRA 2FUSA 1FURA 2O6YA 2PTQA 4ADLA 4MX2A 4EFCA 1GKJA 3R6YA 3R6VA 1J3UA 1GK3A 1DCNA 1TJUA 2O78A 2O7FA 2PTRA 2QGAB 1HY1A 3UNVA 1YISA 4EEIA 3OCFA 4C5RA 3GZHA 1XWOA 1T6JA 4NLEA 1W27A 4FLCA 1C3CA 2NYNA 3RD8A 4BABA 1JSWA 5F91A 1GK2A 1T6PA 3NO9A 1I0AA 4ADMA 2PFMA 4V2QA 2OHYA 1RE5A 1AUWA 1TJWA 2O7DA 2X75A 1KQ7A 1VDKA 5F92A 4NSLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U15 A;  5EYV A;  3CZO A;  1YFM A;  1Q5N A;  1B8F A;  1EB4 A;  1FUQ A;  3OCE A;  3NZ4 A;  3KDY A;  1HY0 A;  2YII A;  1C3U A;  5EYT A;  1FUP A;  3RRP A;  4FFX A;  3TV2 A;  2J91 A;  2RJS A;  2E9F A;  4C5U A;  3E04 A;  2PTS A;  3GTD A;  4V2R A;  1DOF A;  3C8T A;  4APA A;  1Y2M A;  4HGV A;  4CQ5 A;  3QBP A;  4APB A;  4C5S A;  1K62 A;  2VD6 A;  1TJV A;  2QVE A;  1U16 A;  1K7W A;  2NYF A;  5HW2 A;  1TJ7 A;  4BAA A;  1YFE A;  3KDZ A;  4C6G A;  3R6Q A;  1FUO A;  5D6B A;  2O7E A;  2HVG A;  2O7B A;  3BHG A;  1GKM A;  2RJR A;  2FUS A;  1FUR A;  2O6Y A;  2PTQ A;  4ADL A;  4MX2 A;  4EFC A;  1GKJ A;  3R6Y A;  3R6V A;  1J3U A;  1GK3 A;  1DCN A;  1TJU A;  2O78 A;  2O7F A;  2PTR A;  2QGA B;  1HY1 A;  3UNV A;  1YIS A;  4EEI A;  3OCF A;  4C5R A;  3GZH A;  1XWO A;  1T6J A;  4NLE A;  1W27 A;  4FLC A;  1C3C A;  2NYN A;  3RD8 A;  4BAB A;  1JSW A;  5F91 A;  1GK2 A;  1T6P A;  3NO9 A;  1I0A A;  4ADM A;  2PFM A;  4V2Q A;  2OHY A;  1RE5 A;  1AUW A;  1TJW A;  2O7D A;  2X75 A;  1KQ7 A;  1VDK A;  5F92 A;  4NSL A; 
#chains in the Genus database with same CATH topology
 2FEN A;  1U15 A;  5EYV A;  3CZO A;  1YFM A;  1Q5N A;  4MUM A;  1Z4P X;  1B8F A;  1EB4 A;  5M0J A;  1FUQ A;  3OCE A;  3NZ4 A;  4WNL A;  3KDY A;  1HY0 A;  3F4R A;  3F4T A;  1C3U A;  2YII A;  5EYT A;  1FUP A;  3RRP A;  4FFX A;  3TV2 A;  2J91 A;  2RJS A;  2VSF A;  1IW7 D;  2E9F A;  4C5U A;  1Q91 A;  3E04 A;  2PTS A;  3GTD A;  4V2R A;  1DOF A;  3C8T A;  4APA A;  2D28 C;  1Y2M A;  4HGV A;  1U0L A;  2FEL A;  2D27 A;  4CQ5 A;  3QBP A;  4NFL A;  4APB A;  1K62 A;  2VD6 A;  3CRV A;  4C5S A;  2JAO A;  1TJV A;  2QVE A;  1U16 A;  4L6C A;  1K7W A;  2NYF A;  5HW2 A;  1TJ7 A;  3CRW 1;  4BAA A;  1YFE A;  3KDZ A;  2I7D A;  4C6G A;  3R6Q A;  1FUO A;  5D6B A;  2O7E A;  2HVG A;  3BWV A;  4A15 A;  2O7B A;  4YIH A;  1Z4J A;  4MWO A;  3BHG A;  2JAU A;  1GKM A;  2RJR A;  2FUS A;  1FUR A;  4L57 A;  2O6Y A;  2PTQ A;  1XL7 A;  4ADL A;  3CI0 K;  4MX2 A;  4EFC A;  1GKJ A;  3R6Y A;  3F4S A;  1J3U A;  3R6V A;  1XMC A;  1GK3 A;  1DCN A;  1TJU A;  2JAW A;  2O78 A;  1MH9 A;  2O7F A;  2VL7 A;  1Z4I A;  2PTR A;  2QGA B;  2YV5 A;  1HY1 A;  3UNV A;  1YIS A;  4EEI A;  1Z4K A;  4YIK A;  3OCF A;  2RCN A;  4C5R A;  3GZH A;  1XWO A;  1T6J A;  4NLE A;  1W27 A;  4FLC A;  1C3C A;  2NYN A;  3RD8 A;  2JAR A;  4BAB A;  1JSW A;  1T9H A;  5F91 A;  1GK2 A;  1T6P A;  3NO9 A;  1XMD A;  1I0A A;  4L6A A;  1Z4Q A;  4ADM A;  2PFM A;  4V2Q A;  2OHY A;  1Q92 A;  1RE5 A;  3U13 A;  1AUW A;  1Z4M A;  1TJW A;  2O7D A;  3U19 A;  4E88 A;  5M0I A;  1Z4L A;  2X75 A;  1KQ7 A;  1VDK A;  1XL8 A;  5F92 A;  4IQJ M;  1XLY A;  4NSL A;  5H8W A; 
#chains in the Genus database with same CATH homology
 1U15 A;  5EYV A;  3CZO A;  1YFM A;  1Q5N A;  1B8F A;  1EB4 A;  1FUQ A;  3OCE A;  3NZ4 A;  3KDY A;  1HY0 A;  2YII A;  1C3U A;  5EYT A;  1FUP A;  3RRP A;  4FFX A;  3TV2 A;  2J91 A;  2RJS A;  2E9F A;  4C5U A;  3E04 A;  2PTS A;  3GTD A;  4V2R A;  1DOF A;  3C8T A;  4APA A;  1Y2M A;  4HGV A;  4CQ5 A;  3QBP A;  4APB A;  4C5S A;  1K62 A;  2VD6 A;  1TJV A;  2QVE A;  1U16 A;  1K7W A;  2NYF A;  5HW2 A;  1TJ7 A;  4BAA A;  1YFE A;  3KDZ A;  4C6G A;  3R6Q A;  1FUO A;  5D6B A;  2O7E A;  2HVG A;  2O7B A;  3BHG A;  1GKM A;  2RJR A;  2FUS A;  1FUR A;  2O6Y A;  2PTQ A;  4ADL A;  4MX2 A;  4EFC A;  1GKJ A;  3R6Y A;  3R6V A;  1J3U A;  1GK3 A;  1DCN A;  1TJU A;  2O78 A;  2O7F A;  2PTR A;  2QGA B;  1HY1 A;  3UNV A;  1YIS A;  4EEI A;  3OCF A;  4C5R A;  3GZH A;  1XWO A;  1T6J A;  4NLE A;  1W27 A;  4FLC A;  1C3C A;  2NYN A;  3RD8 A;  4BAB A;  1JSW A;  5F91 A;  1GK2 A;  1T6P A;  3NO9 A;  1I0A A;  4ADM A;  2PFM A;  4V2Q A;  2OHY A;  1RE5 A;  1AUW A;  1TJW A;  2O7D A;  2X75 A;  1KQ7 A;  1VDK A;  5F92 A;  4NSL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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