4EEIA

Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with amp and succinate
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
433
structure length
414
Chain Sequence
b'MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRARAQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYEGFKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAYLSSFYLHFLVANTPFMREDCYKIVQQVESFSKKLQKVMHDEHNIILDIPEMDFEGIKKTYLKEIDHVFDRSVKAR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
molecule tags Lyase
source organism Francisella tularensis subsp. tularensis schu s4
publication title Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
rcsb
total genus 166
structure length 414
sequence length 433
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2012-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4eeiA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4eeiA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4eeiA02
3CZOA 1TJUA 4FLCA 2RJSA 4BAAA 4MX2A 1GK2A 5EYVA 1K7WA 1EB4A 1YISA 2NYNA 1DCNA 3E04A 3GZHA 5D6BA 3NO9A 3OCFA 5HW2A 2O7FA 1JSWA 2FUSA 4V2QA 3C8TA 1GK3A 4ADLA 4FFXA 1XWOA 2E9FA 4C5RA 1DOFA 3NZ4A 2YIIA 2RJRA 2PTRA 1TJVA 2PFMA 1U16A 1GKJA 1YFMA 4CQ5A 5F91A 4ADMA 2QGAB 4NLEA 2O7BA 3UNVA 4EEIA 3R6YA 4EFCA 2NYFA 1KQ7A 2O78A 1RE5A 2PTQA 1C3CA 1GKMA 3BHGA 2HVGA 2PTSA 1T6JA 1YFEA 1J3UA 1TJ7A 3GTDA 1T6PA 3RRPA 2O6YA 1I0AA 1Y2MA 1FUQA 3TV2A 2X75A 4APBA 1HY0A 1C3UA 3RD8A 2VD6A 1B8FA 2QVEA 3OCEA 2J91A 1HY1A 2OHYA 4V2RA 3R6VA 3QBPA 4NSLA 4C5UA 2O7EA 3KDYA 1W27A 1FURA 1Q5NA 4C5SA 4BABA 4HGVA 1VDKA 1AUWA 4C6GA 1TJWA 5EYTA 4APAA 5F92A 1U15A 3KDZA 2O7DA 1FUPA 1K62A 1FUOA 3R6QA
chains in the Genus database with same CATH superfamily
2JAUA 3CZOA 1TJUA 2FELA 4FLCA 1Z4LA 2RJSA 1MH9A 1Q91A 4BAAA 4YIHA 4MX2A 1GK2A 5M0JA 5EYVA 4YIKA 1K7WA 1EB4A 1YISA 1DCNA 3E04A 3GZHA 4MUMA 3NO9A 4L6CA 5D6BA 3OCFA 2NYNA 2D28C 5HW2A 4E88A 4NFLA 2O7FA 2JAWA 1JSWA 2FUSA 4V2QA 3C8TA 3F4TA 1GK3A 4ADLA 5H8WA 4FFXA 1XWOA 2E9FA 4C5RA 1DOFA 3NZ4A 2YIIA 5M0IA 2RJRA 3CI0K 2PTRA 1TJVA 2PFMA 2JARA 1U16A 1Z4QA 1YFMA 4L6AA 1GKJA 3F4RA 4CQ5A 5F91A 4ADMA 4IQJM 2VL7A 2QGAB 4NLEA 2O7BA 3UNVA 4EEIA 1Z4KA 3R6YA 4EFCA 2NYFA 1KQ7A 2O78A 1RE5A 1Z4PX 2PTQA 1C3CA 2VSFA 2YV5A 1GKMA 2FENA 4L57A 3BHGA 2RCNA 2HVGA 2PTSA 1T6JA 1YFEA 1XL7A 1J3UA 1TJ7A 3GTDA 1T6PA 2JAOA 3CRW1 4MWOA 3RRPA 2O6YA 1Z4IA 1I0AA 1Y2MA 4A15A 1XL8A 1FUQA 3TV2A 1XMCA 2X75A 1Z4JA 3U19A 4APBA 1HY0A 2I7DA 1C3UA 3RD8A 2VD6A 1XMDA 3F4SA 1B8FA 2QVEA 3BWVA 3OCEA 1Z4MA 2J91A 4WNLA 1IW7D 1HY1A 1XLYA 1T9HA 2OHYA 4V2RA 2D27A 3R6VA 3QBPA 4NSLA 4C5UA 2O7EA 3KDYA 1U0LA 1FURA 1W27A 1Q5NA 4C5SA 4BABA 4HGVA 3U13A 1VDKA 1AUWA 3CRVA 4C6GA 1TJWA 5EYTA 4APAA 5F92A 1U15A 3KDZA 1Q92A 1FUPA 2O7DA 1K62A 1FUOA 3R6QA
chains in the Genus database with same CATH topology
3CZOA 1TJUA 4FLCA 2RJSA 4BAAA 4MX2A 1GK2A 5EYVA 1K7WA 1EB4A 1YISA 2NYNA 1DCNA 3E04A 3GZHA 5D6BA 3NO9A 3OCFA 5HW2A 2O7FA 1JSWA 2FUSA 4V2QA 3C8TA 1GK3A 4ADLA 4FFXA 1XWOA 2E9FA 4C5RA 1DOFA 3NZ4A 2YIIA 2RJRA 2PTRA 1TJVA 2PFMA 1U16A 1GKJA 1YFMA 4CQ5A 5F91A 4ADMA 2QGAB 4NLEA 2O7BA 3UNVA 4EEIA 3R6YA 4EFCA 2NYFA 1KQ7A 2O78A 1RE5A 2PTQA 1C3CA 1GKMA 3BHGA 2HVGA 2PTSA 1T6JA 1YFEA 1J3UA 1TJ7A 3GTDA 1T6PA 3RRPA 2O6YA 1I0AA 1Y2MA 1FUQA 3TV2A 2X75A 4APBA 1HY0A 1C3UA 3RD8A 2VD6A 1B8FA 2QVEA 3OCEA 2J91A 1HY1A 2OHYA 4V2RA 3R6VA 3QBPA 4NSLA 4C5UA 2O7EA 3KDYA 1W27A 1FURA 1Q5NA 4C5SA 4BABA 4HGVA 1VDKA 1AUWA 4C6GA 1TJWA 5EYTA 4APAA 5F92A 1U15A 3KDZA 2O7DA 1FUPA 1K62A 1FUOA 3R6QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CZO A;  1TJU A;  4FLC A;  2RJS A;  4BAA A;  4MX2 A;  1GK2 A;  5EYV A;  1K7W A;  1EB4 A;  1YIS A;  2NYN A;  1DCN A;  3E04 A;  3GZH A;  5D6B A;  3NO9 A;  3OCF A;  5HW2 A;  2O7F A;  1JSW A;  2FUS A;  4V2Q A;  3C8T A;  1GK3 A;  4ADL A;  4FFX A;  1XWO A;  2E9F A;  4C5R A;  1DOF A;  3NZ4 A;  2YII A;  2RJR A;  2PTR A;  1TJV A;  2PFM A;  1U16 A;  1GKJ A;  1YFM A;  4CQ5 A;  5F91 A;  4ADM A;  2QGA B;  4NLE A;  2O7B A;  3UNV A;  4EEI A;  3R6Y A;  4EFC A;  2NYF A;  1KQ7 A;  2O78 A;  1RE5 A;  2PTQ A;  1C3C A;  1GKM A;  3BHG A;  2HVG A;  2PTS A;  1T6J A;  1YFE A;  1J3U A;  1TJ7 A;  3GTD A;  1T6P A;  3RRP A;  2O6Y A;  1I0A A;  1Y2M A;  1FUQ A;  3TV2 A;  2X75 A;  4APB A;  1HY0 A;  1C3U A;  3RD8 A;  2VD6 A;  1B8F A;  2QVE A;  3OCE A;  2J91 A;  1HY1 A;  2OHY A;  4V2R A;  3R6V A;  3QBP A;  4NSL A;  4C5U A;  2O7E A;  3KDY A;  1W27 A;  1FUR A;  1Q5N A;  4C5S A;  4BAB A;  4HGV A;  1VDK A;  1AUW A;  4C6G A;  1TJW A;  5EYT A;  4APA A;  5F92 A;  1U15 A;  3KDZ A;  2O7D A;  1FUP A;  1K62 A;  1FUO A;  3R6Q A; 
#chains in the Genus database with same CATH topology
 2JAU A;  3CZO A;  1TJU A;  2FEL A;  4FLC A;  1Z4L A;  2RJS A;  1MH9 A;  1Q91 A;  4BAA A;  4YIH A;  4MX2 A;  1GK2 A;  5M0J A;  5EYV A;  4YIK A;  1K7W A;  1EB4 A;  1YIS A;  1DCN A;  3E04 A;  3GZH A;  4MUM A;  3NO9 A;  4L6C A;  5D6B A;  3OCF A;  2NYN A;  2D28 C;  5HW2 A;  4E88 A;  4NFL A;  2O7F A;  2JAW A;  1JSW A;  2FUS A;  4V2Q A;  3C8T A;  3F4T A;  1GK3 A;  4ADL A;  5H8W A;  4FFX A;  1XWO A;  2E9F A;  4C5R A;  1DOF A;  3NZ4 A;  2YII A;  5M0I A;  2RJR A;  3CI0 K;  2PTR A;  1TJV A;  2PFM A;  2JAR A;  1U16 A;  1Z4Q A;  1YFM A;  4L6A A;  1GKJ A;  3F4R A;  4CQ5 A;  5F91 A;  4ADM A;  4IQJ M;  2VL7 A;  2QGA B;  4NLE A;  2O7B A;  3UNV A;  4EEI A;  1Z4K A;  3R6Y A;  4EFC A;  2NYF A;  1KQ7 A;  2O78 A;  1RE5 A;  1Z4P X;  2PTQ A;  1C3C A;  2VSF A;  2YV5 A;  1GKM A;  2FEN A;  4L57 A;  3BHG A;  2RCN A;  2HVG A;  2PTS A;  1T6J A;  1YFE A;  1XL7 A;  1J3U A;  1TJ7 A;  3GTD A;  1T6P A;  2JAO A;  3CRW 1;  4MWO A;  3RRP A;  2O6Y A;  1Z4I A;  1I0A A;  1Y2M A;  4A15 A;  1XL8 A;  1FUQ A;  3TV2 A;  1XMC A;  2X75 A;  1Z4J A;  3U19 A;  4APB A;  1HY0 A;  2I7D A;  1C3U A;  3RD8 A;  2VD6 A;  1XMD A;  3F4S A;  1B8F A;  2QVE A;  3BWV A;  3OCE A;  1Z4M A;  2J91 A;  4WNL A;  1IW7 D;  1HY1 A;  1XLY A;  1T9H A;  2OHY A;  4V2R A;  2D27 A;  3R6V A;  3QBP A;  4NSL A;  4C5U A;  2O7E A;  3KDY A;  1U0L A;  1FUR A;  1W27 A;  1Q5N A;  4C5S A;  4BAB A;  4HGV A;  3U13 A;  1VDK A;  1AUW A;  3CRV A;  4C6G A;  1TJW A;  5EYT A;  4APA A;  5F92 A;  1U15 A;  3KDZ A;  1Q92 A;  1FUP A;  2O7D A;  1K62 A;  1FUO A;  3R6Q A; 
#chains in the Genus database with same CATH homology
 3CZO A;  1TJU A;  4FLC A;  2RJS A;  4BAA A;  4MX2 A;  1GK2 A;  5EYV A;  1K7W A;  1EB4 A;  1YIS A;  2NYN A;  1DCN A;  3E04 A;  3GZH A;  5D6B A;  3NO9 A;  3OCF A;  5HW2 A;  2O7F A;  1JSW A;  2FUS A;  4V2Q A;  3C8T A;  1GK3 A;  4ADL A;  4FFX A;  1XWO A;  2E9F A;  4C5R A;  1DOF A;  3NZ4 A;  2YII A;  2RJR A;  2PTR A;  1TJV A;  2PFM A;  1U16 A;  1GKJ A;  1YFM A;  4CQ5 A;  5F91 A;  4ADM A;  2QGA B;  4NLE A;  2O7B A;  3UNV A;  4EEI A;  3R6Y A;  4EFC A;  2NYF A;  1KQ7 A;  2O78 A;  1RE5 A;  2PTQ A;  1C3C A;  1GKM A;  3BHG A;  2HVG A;  2PTS A;  1T6J A;  1YFE A;  1J3U A;  1TJ7 A;  3GTD A;  1T6P A;  3RRP A;  2O6Y A;  1I0A A;  1Y2M A;  1FUQ A;  3TV2 A;  2X75 A;  4APB A;  1HY0 A;  1C3U A;  3RD8 A;  2VD6 A;  1B8F A;  2QVE A;  3OCE A;  2J91 A;  1HY1 A;  2OHY A;  4V2R A;  3R6V A;  3QBP A;  4NSL A;  4C5U A;  2O7E A;  3KDY A;  1W27 A;  1FUR A;  1Q5N A;  4C5S A;  4BAB A;  4HGV A;  1VDK A;  1AUW A;  4C6G A;  1TJW A;  5EYT A;  4APA A;  5F92 A;  1U15 A;  3KDZ A;  2O7D A;  1FUP A;  1K62 A;  1FUO A;  3R6Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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