4EEIA

Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with amp and succinate
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
433
structure length
414
Chain Sequence
MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRARAQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYEGFKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAYLSSFYLHFLVANTPFMREDCYKIVQQVESFSKKLQKVMHDEHNIILDIPEMDFEGIKKTYLKEIDHVFDRSVKAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
rcsb
source organism Francisella tularensis subsp. tularensis schu s4
molecule tags Lyase
molecule keywords Adenylosuccinate lyase
total genus 166
structure length 414
sequence length 433
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2012-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4eeiA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4eeiA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4eeiA02
1TJWA 3KDZA 1Y2MA 4NLEA 5D6BA 4NSLA 1TJVA 3UNVA 4BAAA 2PTRA 4APBA 1U16A 1B8FA 3R6QA 5F91A 1HY0A 3RRPA 4HGVA 2QVEA 4CQ5A 2RJRA 3E04A 4C5SA 2FUSA 1Q5NA 1GKMA 1YFEA 2X75A 3NO9A 1JSWA 1T6PA 2PTQA 1J3UA 2O7BA 4ADMA 1K7WA 1GK2A 2O78A 2HVGA 1YISA 2O7FA 2O7DA 4C6GA 2YIIA 4V2RA 1TJUA 1YFMA 3QBPA 2J91A 2NYFA 4C5RA 1FUPA 3BHGA 3KDYA 5HW2A 3CZOA 2PFMA 1FURA 1U15A 4EEIA 3TV2A 1XWOA 1DCNA 1T6JA 1DOFA 2O6YA 3NZ4A 4C5UA 4MX2A 3RD8A 4ADLA 1AUWA 2VD6A 1K62A 4BABA 3GZHA 2PTSA 1FUQA 2OHYA 5EYVA 1VDKA 3R6YA 1C3UA 1HY1A 1TJ7A 2RJSA 5F92A 4APAA 3GTDA 1C3CA 4EFCA 4V2QA 3OCEA 1FUOA 3R6VA 1W27A 2QGAB 2E9FA 2NYNA 1RE5A 1I0AA 3OCFA 1GK3A 1GKJA 4FLCA 3C8TA 1KQ7A 4FFXA 5EYTA 2O7EA 1EB4A
chains in the Genus database with same CATH superfamily
1TJWA 3KDZA 1Y2MA 3CRVA 4NLEA 5D6BA 4YIKA 4NSLA 1TJVA 2JARA 3UNVA 4BAAA 2PTRA 4APBA 1U16A 1B8FA 3R6QA 5F91A 1HY0A 3RRPA 3F4RA 4HGVA 2QVEA 4CQ5A 2RJRA 2VL7A 1XLYA 3E04A 4C5SA 2FUSA 4L6AA 2JAWA 1Q5NA 1GKMA 1YFEA 2X75A 3NO9A 1JSWA 2VSFA 2FENA 1T6PA 5H8WA 2PTQA 1J3UA 2O7BA 2JAOA 4ADMA 1Z4IA 1K7WA 1GK2A 1IW7D 1Z4PX 1Z4JA 3CI0K 1Q92A 4E88A 1XMDA 2O78A 2HVGA 1YISA 2O7FA 4NFLA 2O7DA 4C6GA 2YIIA 4V2RA 1TJUA 2D27A 4L6CA 1YFMA 3QBPA 2J91A 2NYFA 1U0LA 4C5RA 1FUPA 2D28C 3BHGA 3KDYA 5HW2A 3U19A 3F4TA 3CZOA 3F4SA 1MH9A 4YIHA 4L57A 2PFMA 2FELA 1FURA 1U15A 5M0IA 4EEIA 3TV2A 1XWOA 2JAUA 1DCNA 1T6JA 1DOFA 2O6YA 3NZ4A 1XMCA 4C5UA 1Z4MA 4MX2A 3CRW1 3RD8A 4ADLA 2I7DA 4IQJM 1AUWA 2VD6A 1Q91A 1K62A 4MUMA 4BABA 3GZHA 2PTSA 1FUQA 3U13A 2OHYA 5EYVA 1Z4KA 1VDKA 1XL8A 3R6YA 4A15A 1C3UA 1HY1A 1TJ7A 2RJSA 4APAA 5F92A 4WNLA 3GTDA 1C3CA 2RCNA 3BWVA 4EFCA 4V2QA 3OCEA 1FUOA 3R6VA 1W27A 2QGAB 1XL7A 2E9FA 2YV5A 2NYNA 1RE5A 1I0AA 4MWOA 3OCFA 1GK3A 1Z4QA 1GKJA 4FLCA 3C8TA 1KQ7A 1T9HA 4FFXA 5M0JA 5EYTA 2O7EA 1EB4A 1Z4LA
chains in the Genus database with same CATH topology
1TJWA 3KDZA 1Y2MA 4NLEA 5D6BA 4NSLA 1TJVA 3UNVA 4BAAA 2PTRA 4APBA 1U16A 1B8FA 3R6QA 5F91A 1HY0A 3RRPA 4HGVA 2QVEA 4CQ5A 2RJRA 3E04A 4C5SA 2FUSA 1Q5NA 1GKMA 1YFEA 2X75A 3NO9A 1JSWA 1T6PA 2PTQA 1J3UA 2O7BA 4ADMA 1K7WA 1GK2A 2O78A 2HVGA 1YISA 2O7FA 2O7DA 4C6GA 2YIIA 4V2RA 1TJUA 1YFMA 3QBPA 2J91A 2NYFA 4C5RA 1FUPA 3BHGA 3KDYA 5HW2A 3CZOA 2PFMA 1FURA 1U15A 4EEIA 3TV2A 1XWOA 1DCNA 1T6JA 1DOFA 2O6YA 3NZ4A 4C5UA 4MX2A 3RD8A 4ADLA 1AUWA 2VD6A 1K62A 4BABA 3GZHA 2PTSA 1FUQA 2OHYA 5EYVA 1VDKA 3R6YA 1C3UA 1HY1A 1TJ7A 2RJSA 5F92A 4APAA 3GTDA 1C3CA 4EFCA 4V2QA 3OCEA 1FUOA 3R6VA 1W27A 2QGAB 2E9FA 2NYNA 1RE5A 1I0AA 3OCFA 1GK3A 1GKJA 4FLCA 3C8TA 1KQ7A 4FFXA 5EYTA 2O7EA 1EB4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TJW A;  3KDZ A;  1Y2M A;  4NLE A;  5D6B A;  4NSL A;  1TJV A;  3UNV A;  4BAA A;  2PTR A;  4APB A;  1U16 A;  1B8F A;  3R6Q A;  5F91 A;  1HY0 A;  3RRP A;  4HGV A;  2QVE A;  4CQ5 A;  2RJR A;  3E04 A;  4C5S A;  2FUS A;  1Q5N A;  1GKM A;  1YFE A;  2X75 A;  3NO9 A;  1JSW A;  1T6P A;  2PTQ A;  1J3U A;  2O7B A;  4ADM A;  1K7W A;  1GK2 A;  2O78 A;  2HVG A;  1YIS A;  2O7F A;  2O7D A;  4C6G A;  2YII A;  4V2R A;  1TJU A;  1YFM A;  3QBP A;  2J91 A;  2NYF A;  4C5R A;  1FUP A;  3BHG A;  3KDY A;  5HW2 A;  3CZO A;  2PFM A;  1FUR A;  1U15 A;  4EEI A;  3TV2 A;  1XWO A;  1DCN A;  1T6J A;  1DOF A;  2O6Y A;  3NZ4 A;  4C5U A;  4MX2 A;  3RD8 A;  4ADL A;  1AUW A;  2VD6 A;  1K62 A;  4BAB A;  3GZH A;  2PTS A;  1FUQ A;  2OHY A;  5EYV A;  1VDK A;  3R6Y A;  1C3U A;  1HY1 A;  1TJ7 A;  2RJS A;  5F92 A;  4APA A;  3GTD A;  1C3C A;  4EFC A;  4V2Q A;  3OCE A;  1FUO A;  3R6V A;  1W27 A;  2QGA B;  2E9F A;  2NYN A;  1RE5 A;  1I0A A;  3OCF A;  1GK3 A;  1GKJ A;  4FLC A;  3C8T A;  1KQ7 A;  4FFX A;  5EYT A;  2O7E A;  1EB4 A; 
#chains in the Genus database with same CATH topology
 1TJW A;  3KDZ A;  1Y2M A;  3CRV A;  4NLE A;  5D6B A;  4YIK A;  4NSL A;  1TJV A;  2JAR A;  3UNV A;  4BAA A;  2PTR A;  4APB A;  1U16 A;  1B8F A;  3R6Q A;  5F91 A;  1HY0 A;  3RRP A;  3F4R A;  4HGV A;  2QVE A;  4CQ5 A;  2RJR A;  2VL7 A;  1XLY A;  3E04 A;  4C5S A;  2FUS A;  4L6A A;  2JAW A;  1Q5N A;  1GKM A;  1YFE A;  2X75 A;  3NO9 A;  1JSW A;  2VSF A;  2FEN A;  1T6P A;  5H8W A;  2PTQ A;  1J3U A;  2O7B A;  2JAO A;  4ADM A;  1Z4I A;  1K7W A;  1GK2 A;  1IW7 D;  1Z4P X;  1Z4J A;  3CI0 K;  1Q92 A;  4E88 A;  1XMD A;  2O78 A;  2HVG A;  1YIS A;  2O7F A;  4NFL A;  2O7D A;  4C6G A;  2YII A;  4V2R A;  1TJU A;  2D27 A;  4L6C A;  1YFM A;  3QBP A;  2J91 A;  2NYF A;  1U0L A;  4C5R A;  1FUP A;  2D28 C;  3BHG A;  3KDY A;  5HW2 A;  3U19 A;  3F4T A;  3CZO A;  3F4S A;  1MH9 A;  4YIH A;  4L57 A;  2PFM A;  2FEL A;  1FUR A;  1U15 A;  5M0I A;  4EEI A;  3TV2 A;  1XWO A;  2JAU A;  1DCN A;  1T6J A;  1DOF A;  2O6Y A;  3NZ4 A;  1XMC A;  4C5U A;  1Z4M A;  4MX2 A;  3CRW 1;  3RD8 A;  4ADL A;  2I7D A;  4IQJ M;  1AUW A;  2VD6 A;  1Q91 A;  1K62 A;  4MUM A;  4BAB A;  3GZH A;  2PTS A;  1FUQ A;  3U13 A;  2OHY A;  5EYV A;  1Z4K A;  1VDK A;  1XL8 A;  3R6Y A;  4A15 A;  1C3U A;  1HY1 A;  1TJ7 A;  2RJS A;  4APA A;  5F92 A;  4WNL A;  3GTD A;  1C3C A;  2RCN A;  3BWV A;  4EFC A;  4V2Q A;  3OCE A;  1FUO A;  3R6V A;  1W27 A;  2QGA B;  1XL7 A;  2E9F A;  2YV5 A;  2NYN A;  1RE5 A;  1I0A A;  4MWO A;  3OCF A;  1GK3 A;  1Z4Q A;  1GKJ A;  4FLC A;  3C8T A;  1KQ7 A;  1T9H A;  4FFX A;  5M0J A;  5EYT A;  2O7E A;  1EB4 A;  1Z4L A; 
#chains in the Genus database with same CATH homology
 1TJW A;  3KDZ A;  1Y2M A;  4NLE A;  5D6B A;  4NSL A;  1TJV A;  3UNV A;  4BAA A;  2PTR A;  4APB A;  1U16 A;  1B8F A;  3R6Q A;  5F91 A;  1HY0 A;  3RRP A;  4HGV A;  2QVE A;  4CQ5 A;  2RJR A;  3E04 A;  4C5S A;  2FUS A;  1Q5N A;  1GKM A;  1YFE A;  2X75 A;  3NO9 A;  1JSW A;  1T6P A;  2PTQ A;  1J3U A;  2O7B A;  4ADM A;  1K7W A;  1GK2 A;  2O78 A;  2HVG A;  1YIS A;  2O7F A;  2O7D A;  4C6G A;  2YII A;  4V2R A;  1TJU A;  1YFM A;  3QBP A;  2J91 A;  2NYF A;  4C5R A;  1FUP A;  3BHG A;  3KDY A;  5HW2 A;  3CZO A;  2PFM A;  1FUR A;  1U15 A;  4EEI A;  3TV2 A;  1XWO A;  1DCN A;  1T6J A;  1DOF A;  2O6Y A;  3NZ4 A;  4C5U A;  4MX2 A;  3RD8 A;  4ADL A;  1AUW A;  2VD6 A;  1K62 A;  4BAB A;  3GZH A;  2PTS A;  1FUQ A;  2OHY A;  5EYV A;  1VDK A;  3R6Y A;  1C3U A;  1HY1 A;  1TJ7 A;  2RJS A;  5F92 A;  4APA A;  3GTD A;  1C3C A;  4EFC A;  4V2Q A;  3OCE A;  1FUO A;  3R6V A;  1W27 A;  2QGA B;  2E9F A;  2NYN A;  1RE5 A;  1I0A A;  3OCF A;  1GK3 A;  1GKJ A;  4FLC A;  3C8T A;  1KQ7 A;  4FFX A;  5EYT A;  2O7E A;  1EB4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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