4EEIA

Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with amp and succinate
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
433
structure length
414
Chain Sequence
MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRARAQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYEGFKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAYLSSFYLHFLVANTPFMREDCYKIVQQVESFSKKLQKVMHDEHNIILDIPEMDFEGIKKTYLKEIDHVFDRSVKAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
rcsb
source organism Francisella tularensis subsp. tularensis schu s4
molecule tags Lyase
total genus 166
structure length 414
sequence length 433
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2012-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4eeiA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4eeiA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4eeiA02
1JSWA 3C8TA 3BHGA 4FLCA 2X75A 3TV2A 4C5UA 4EFCA 2PTSA 2PFMA 1GK2A 4FFXA 3E04A 4CQ5A 1TJ7A 5F92A 3R6VA 2NYNA 1FUQA 4NSLA 1Q5NA 4APAA 2YIIA 1YISA 2RJSA 1T6JA 1C3CA 3CZOA 4V2RA 4C6GA 4BABA 2HVGA 4NLEA 1HY0A 4C5RA 3R6YA 2RJRA 3OCEA 3OCFA 2QVEA 4V2QA 1J3UA 1VDKA 2PTQA 3RRPA 3QBPA 1YFMA 4HGVA 5EYTA 1DOFA 1K7WA 1Y2MA 1TJWA 1AUWA 1EB4A 1B8FA 3R6QA 1TJVA 1XWOA 1KQ7A 3UNVA 1C3UA 5HW2A 1GKJA 2O7DA 1U16A 1RE5A 4C5SA 2J91A 3KDYA 2O78A 2FUSA 1TJUA 1T6PA 2VD6A 1FUPA 1HY1A 4ADMA 1GKMA 2NYFA 4ADLA 2O7FA 3GZHA 1GK3A 1K62A 5D6BA 3NO9A 1DCNA 3KDZA 2PTRA 4BAAA 2OHYA 4APBA 2O6YA 2O7BA 1I0AA 2O7EA 1W27A 4MX2A 1YFEA 1FURA 1U15A 1FUOA 3GTDA 5F91A 3RD8A 2QGAB 2E9FA 4EEIA 5EYVA 3NZ4A
chains in the Genus database with same CATH superfamily
1Z4IA 1JSWA 3U19A 3C8TA 3BHGA 4FLCA 2X75A 2D27A 3TV2A 4C5UA 4EFCA 2PTSA 2PFMA 1GK2A 4FFXA 3E04A 3F4TA 3F4SA 4CQ5A 1TJ7A 5F92A 3R6VA 4MUMA 1XLYA 1Z4PX 2NYNA 1FUQA 4NSLA 4IQJM 1Q5NA 4APAA 2YIIA 1YISA 1T9HA 2RJSA 2I7DA 2FELA 1T6JA 1C3CA 3CZOA 1MH9A 1Q92A 2D28C 2JAUA 2JARA 4V2RA 1XMCA 4YIHA 4C6GA 4L57A 1XMDA 4BABA 2HVGA 2RCNA 4NLEA 1HY0A 4C5RA 3R6YA 2RJRA 5M0IA 3OCEA 2VL7A 4L6CA 3OCFA 2QVEA 4V2QA 5M0JA 1J3UA 1VDKA 1Q91A 2PTQA 3RRPA 3QBPA 1YFMA 4HGVA 5EYTA 1DOFA 1K7WA 4YIKA 1Z4JA 1Y2MA 1TJWA 1Z4MA 1XL7A 4WNLA 1AUWA 1EB4A 5H8WA 1B8FA 3R6QA 1TJVA 1XWOA 1XL8A 1KQ7A 3UNVA 1C3UA 5HW2A 3BWVA 1GKJA 2O7DA 1U16A 1RE5A 3F4RA 4C5SA 3U13A 2FENA 2J91A 1U0LA 3KDYA 3CI0K 2O78A 2FUSA 1TJUA 1T6PA 2VD6A 1FUPA 1HY1A 4ADMA 1GKMA 2NYFA 3CRVA 2JAOA 4ADLA 2O7FA 3GZHA 1GK3A 1Z4LA 1K62A 5D6BA 3NO9A 1DCNA 3KDZA 2PTRA 1Z4KA 4BAAA 2OHYA 3CRW1 4APBA 2VSFA 2O6YA 4A15A 4NFLA 2O7BA 1Z4QA 1I0AA 2O7EA 1IW7D 1W27A 4L6AA 2JAWA 4MX2A 1YFEA 1FURA 4E88A 1U15A 4MWOA 1FUOA 3GTDA 5F91A 3RD8A 2QGAB 2YV5A 2E9FA 4EEIA 5EYVA 3NZ4A
chains in the Genus database with same CATH topology
1JSWA 3C8TA 3BHGA 4FLCA 2X75A 3TV2A 4C5UA 4EFCA 2PTSA 2PFMA 1GK2A 4FFXA 3E04A 4CQ5A 1TJ7A 5F92A 3R6VA 2NYNA 1FUQA 4NSLA 1Q5NA 4APAA 2YIIA 1YISA 2RJSA 1T6JA 1C3CA 3CZOA 4V2RA 4C6GA 4BABA 2HVGA 4NLEA 1HY0A 4C5RA 3R6YA 2RJRA 3OCEA 3OCFA 2QVEA 4V2QA 1J3UA 1VDKA 2PTQA 3RRPA 3QBPA 1YFMA 4HGVA 5EYTA 1DOFA 1K7WA 1Y2MA 1TJWA 1AUWA 1EB4A 1B8FA 3R6QA 1TJVA 1XWOA 1KQ7A 3UNVA 1C3UA 5HW2A 1GKJA 2O7DA 1U16A 1RE5A 4C5SA 2J91A 3KDYA 2O78A 2FUSA 1TJUA 1T6PA 2VD6A 1FUPA 1HY1A 4ADMA 1GKMA 2NYFA 4ADLA 2O7FA 3GZHA 1GK3A 1K62A 5D6BA 3NO9A 1DCNA 3KDZA 2PTRA 4BAAA 2OHYA 4APBA 2O6YA 2O7BA 1I0AA 2O7EA 1W27A 4MX2A 1YFEA 1FURA 1U15A 1FUOA 3GTDA 5F91A 3RD8A 2QGAB 2E9FA 4EEIA 5EYVA 3NZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JSW A;  3C8T A;  3BHG A;  4FLC A;  2X75 A;  3TV2 A;  4C5U A;  4EFC A;  2PTS A;  2PFM A;  1GK2 A;  4FFX A;  3E04 A;  4CQ5 A;  1TJ7 A;  5F92 A;  3R6V A;  2NYN A;  1FUQ A;  4NSL A;  1Q5N A;  4APA A;  2YII A;  1YIS A;  2RJS A;  1T6J A;  1C3C A;  3CZO A;  4V2R A;  4C6G A;  4BAB A;  2HVG A;  4NLE A;  1HY0 A;  4C5R A;  3R6Y A;  2RJR A;  3OCE A;  3OCF A;  2QVE A;  4V2Q A;  1J3U A;  1VDK A;  2PTQ A;  3RRP A;  3QBP A;  1YFM A;  4HGV A;  5EYT A;  1DOF A;  1K7W A;  1Y2M A;  1TJW A;  1AUW A;  1EB4 A;  1B8F A;  3R6Q A;  1TJV A;  1XWO A;  1KQ7 A;  3UNV A;  1C3U A;  5HW2 A;  1GKJ A;  2O7D A;  1U16 A;  1RE5 A;  4C5S A;  2J91 A;  3KDY A;  2O78 A;  2FUS A;  1TJU A;  1T6P A;  2VD6 A;  1FUP A;  1HY1 A;  4ADM A;  1GKM A;  2NYF A;  4ADL A;  2O7F A;  3GZH A;  1GK3 A;  1K62 A;  5D6B A;  3NO9 A;  1DCN A;  3KDZ A;  2PTR A;  4BAA A;  2OHY A;  4APB A;  2O6Y A;  2O7B A;  1I0A A;  2O7E A;  1W27 A;  4MX2 A;  1YFE A;  1FUR A;  1U15 A;  1FUO A;  3GTD A;  5F91 A;  3RD8 A;  2QGA B;  2E9F A;  4EEI A;  5EYV A;  3NZ4 A; 
#chains in the Genus database with same CATH topology
 1Z4I A;  1JSW A;  3U19 A;  3C8T A;  3BHG A;  4FLC A;  2X75 A;  2D27 A;  3TV2 A;  4C5U A;  4EFC A;  2PTS A;  2PFM A;  1GK2 A;  4FFX A;  3E04 A;  3F4T A;  3F4S A;  4CQ5 A;  1TJ7 A;  5F92 A;  3R6V A;  4MUM A;  1XLY A;  1Z4P X;  2NYN A;  1FUQ A;  4NSL A;  4IQJ M;  1Q5N A;  4APA A;  2YII A;  1YIS A;  1T9H A;  2RJS A;  2I7D A;  2FEL A;  1T6J A;  1C3C A;  3CZO A;  1MH9 A;  1Q92 A;  2D28 C;  2JAU A;  2JAR A;  4V2R A;  1XMC A;  4YIH A;  4C6G A;  4L57 A;  1XMD A;  4BAB A;  2HVG A;  2RCN A;  4NLE A;  1HY0 A;  4C5R A;  3R6Y A;  2RJR A;  5M0I A;  3OCE A;  2VL7 A;  4L6C A;  3OCF A;  2QVE A;  4V2Q A;  5M0J A;  1J3U A;  1VDK A;  1Q91 A;  2PTQ A;  3RRP A;  3QBP A;  1YFM A;  4HGV A;  5EYT A;  1DOF A;  1K7W A;  4YIK A;  1Z4J A;  1Y2M A;  1TJW A;  1Z4M A;  1XL7 A;  4WNL A;  1AUW A;  1EB4 A;  5H8W A;  1B8F A;  3R6Q A;  1TJV A;  1XWO A;  1XL8 A;  1KQ7 A;  3UNV A;  1C3U A;  5HW2 A;  3BWV A;  1GKJ A;  2O7D A;  1U16 A;  1RE5 A;  3F4R A;  4C5S A;  3U13 A;  2FEN A;  2J91 A;  1U0L A;  3KDY A;  3CI0 K;  2O78 A;  2FUS A;  1TJU A;  1T6P A;  2VD6 A;  1FUP A;  1HY1 A;  4ADM A;  1GKM A;  2NYF A;  3CRV A;  2JAO A;  4ADL A;  2O7F A;  3GZH A;  1GK3 A;  1Z4L A;  1K62 A;  5D6B A;  3NO9 A;  1DCN A;  3KDZ A;  2PTR A;  1Z4K A;  4BAA A;  2OHY A;  3CRW 1;  4APB A;  2VSF A;  2O6Y A;  4A15 A;  4NFL A;  2O7B A;  1Z4Q A;  1I0A A;  2O7E A;  1IW7 D;  1W27 A;  4L6A A;  2JAW A;  4MX2 A;  1YFE A;  1FUR A;  4E88 A;  1U15 A;  4MWO A;  1FUO A;  3GTD A;  5F91 A;  3RD8 A;  2QGA B;  2YV5 A;  2E9F A;  4EEI A;  5EYV A;  3NZ4 A; 
#chains in the Genus database with same CATH homology
 1JSW A;  3C8T A;  3BHG A;  4FLC A;  2X75 A;  3TV2 A;  4C5U A;  4EFC A;  2PTS A;  2PFM A;  1GK2 A;  4FFX A;  3E04 A;  4CQ5 A;  1TJ7 A;  5F92 A;  3R6V A;  2NYN A;  1FUQ A;  4NSL A;  1Q5N A;  4APA A;  2YII A;  1YIS A;  2RJS A;  1T6J A;  1C3C A;  3CZO A;  4V2R A;  4C6G A;  4BAB A;  2HVG A;  4NLE A;  1HY0 A;  4C5R A;  3R6Y A;  2RJR A;  3OCE A;  3OCF A;  2QVE A;  4V2Q A;  1J3U A;  1VDK A;  2PTQ A;  3RRP A;  3QBP A;  1YFM A;  4HGV A;  5EYT A;  1DOF A;  1K7W A;  1Y2M A;  1TJW A;  1AUW A;  1EB4 A;  1B8F A;  3R6Q A;  1TJV A;  1XWO A;  1KQ7 A;  3UNV A;  1C3U A;  5HW2 A;  1GKJ A;  2O7D A;  1U16 A;  1RE5 A;  4C5S A;  2J91 A;  3KDY A;  2O78 A;  2FUS A;  1TJU A;  1T6P A;  2VD6 A;  1FUP A;  1HY1 A;  4ADM A;  1GKM A;  2NYF A;  4ADL A;  2O7F A;  3GZH A;  1GK3 A;  1K62 A;  5D6B A;  3NO9 A;  1DCN A;  3KDZ A;  2PTR A;  4BAA A;  2OHY A;  4APB A;  2O6Y A;  2O7B A;  1I0A A;  2O7E A;  1W27 A;  4MX2 A;  1YFE A;  1FUR A;  1U15 A;  1FUO A;  3GTD A;  5F91 A;  3RD8 A;  2QGA B;  2E9F A;  4EEI A;  5EYV A;  3NZ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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