4EEIA

Crystal structure of adenylosuccinate lyase from francisella tularensis complexed with amp and succinate
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
433
structure length
414
Chain Sequence
MIKRYDVAEISKIWADENKYAKMLEVELAILEALEDRMVPKGTAAEIRARAQIRPERVDEIEKVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADILGLPVEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYEGFKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAYLSSFYLHFLVANTPFMREDCYKIVQQVESFSKKLQKVMHDEHNIILDIPEMDFEGIKKTYLKEIDHVFDRSVKAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
rcsb
source organism Francisella tularensis subsp. tularensis schu s4
molecule tags Lyase
total genus 166
structure length 414
sequence length 433
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2012-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4eeiA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4eeiA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4eeiA02
1TJUA 1U15A 1EB4A 4V2RA 5HW2A 1FURA 4NLEA 3GTDA 3KDYA 1FUOA 3RRPA 3R6VA 2PFMA 1YFEA 1TJ7A 3GZHA 3OCFA 4NSLA 4EEIA 1DCNA 4EFCA 4C5RA 1AUWA 4BABA 2QGAB 3UNVA 2RJSA 1RE5A 1XWOA 2O7DA 4ADLA 4APBA 1TJVA 1Q5NA 2OHYA 3R6QA 4MX2A 3CZOA 1J3UA 2HVGA 2PTRA 1W27A 1YISA 1FUPA 4V2QA 4FFXA 1HY0A 2O7FA 1TJWA 2O6YA 5EYTA 2E9FA 2YIIA 2RJRA 1KQ7A 4FLCA 2O7BA 4BAAA 1I0AA 5D6BA 3TV2A 1GK2A 1JSWA 3OCEA 2NYNA 3R6YA 1HY1A 2O7EA 3NZ4A 1GKMA 2VD6A 1GKJA 1T6JA 2X75A 1B8FA 3QBPA 1C3CA 4HGVA 3E04A 1K7WA 1K62A 2FUSA 3KDZA 4CQ5A 1U16A 2QVEA 4ADMA 4C5UA 4APAA 1YFMA 1VDKA 1C3UA 1Y2MA 2J91A 1DOFA 1T6PA 2PTQA 4C6GA 3BHGA 3RD8A 1GK3A 5F92A 1FUQA 5F91A 4C5SA 5EYVA 3C8TA 3NO9A 2O78A 2NYFA 2PTSA
chains in the Genus database with same CATH superfamily
3U13A 1T9HA 1Z4KA 1TJUA 1U15A 1EB4A 3CRVA 1XMCA 4V2RA 5M0JA 5HW2A 1FURA 1Z4IA 4NLEA 3GTDA 4MUMA 2I7DA 3KDYA 1FUOA 3RRPA 4L6CA 4NFLA 2PFMA 3R6VA 1YFEA 1TJ7A 3GZHA 3OCFA 4NSLA 4EEIA 1DCNA 4EFCA 4C5RA 4MWOA 2JAUA 1AUWA 4IQJM 3CI0K 4BABA 2QGAB 3UNVA 5H8WA 2RJSA 1RE5A 1XWOA 2O7DA 2D28C 4L6AA 4ADLA 4APBA 1TJVA 1Q5NA 2OHYA 3R6QA 4MX2A 3CZOA 1J3UA 4YIHA 1U0LA 2HVGA 1XL8A 2PTRA 1W27A 1YISA 1FUPA 4V2QA 4FFXA 1HY0A 2O7FA 1TJWA 2O6YA 3F4TA 5EYTA 2E9FA 2YIIA 2RJRA 1KQ7A 2FENA 4FLCA 2O7BA 3U19A 4BAAA 2VSFA 2YV5A 1I0AA 5D6BA 3TV2A 1GK2A 1JSWA 1Z4QA 3OCEA 2NYNA 3R6YA 1HY1A 4YIKA 1Z4MA 4L57A 2FELA 2O7EA 3NZ4A 3CRW1 2VL7A 1GKMA 2VD6A 1GKJA 1T6JA 2RCNA 2JAWA 3F4SA 2X75A 1XL7A 1Q92A 1B8FA 5M0IA 2JARA 1Z4PX 1C3CA 3QBPA 2JAOA 4HGVA 1XMDA 3E04A 1K7WA 1K62A 2FUSA 3KDZA 4CQ5A 1U16A 2QVEA 4ADMA 4E88A 4C5UA 4APAA 1YFMA 1VDKA 1Z4JA 1C3UA 1Y2MA 2J91A 1DOFA 1Z4LA 1T6PA 2PTQA 4C6GA 3F4RA 3BHGA 4WNLA 3RD8A 1GK3A 5F92A 1MH9A 1FUQA 5F91A 2D27A 4C5SA 5EYVA 3C8TA 1IW7D 1XLYA 3NO9A 2O78A 1Q91A 2NYFA 3BWVA 4A15A 2PTSA
chains in the Genus database with same CATH topology
1TJUA 1U15A 1EB4A 4V2RA 5HW2A 1FURA 4NLEA 3GTDA 3KDYA 1FUOA 3RRPA 3R6VA 2PFMA 1YFEA 1TJ7A 3GZHA 3OCFA 4NSLA 4EEIA 1DCNA 4EFCA 4C5RA 1AUWA 4BABA 2QGAB 3UNVA 2RJSA 1RE5A 1XWOA 2O7DA 4ADLA 4APBA 1TJVA 1Q5NA 2OHYA 3R6QA 4MX2A 3CZOA 1J3UA 2HVGA 2PTRA 1W27A 1YISA 1FUPA 4V2QA 4FFXA 1HY0A 2O7FA 1TJWA 2O6YA 5EYTA 2E9FA 2YIIA 2RJRA 1KQ7A 4FLCA 2O7BA 4BAAA 1I0AA 5D6BA 3TV2A 1GK2A 1JSWA 3OCEA 2NYNA 3R6YA 1HY1A 2O7EA 3NZ4A 1GKMA 2VD6A 1GKJA 1T6JA 2X75A 1B8FA 3QBPA 1C3CA 4HGVA 3E04A 1K7WA 1K62A 2FUSA 3KDZA 4CQ5A 1U16A 2QVEA 4ADMA 4C5UA 4APAA 1YFMA 1VDKA 1C3UA 1Y2MA 2J91A 1DOFA 1T6PA 2PTQA 4C6GA 3BHGA 3RD8A 1GK3A 5F92A 1FUQA 5F91A 4C5SA 5EYVA 3C8TA 3NO9A 2O78A 2NYFA 2PTSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TJU A;  1U15 A;  1EB4 A;  4V2R A;  5HW2 A;  1FUR A;  4NLE A;  3GTD A;  3KDY A;  1FUO A;  3RRP A;  3R6V A;  2PFM A;  1YFE A;  1TJ7 A;  3GZH A;  3OCF A;  4NSL A;  4EEI A;  1DCN A;  4EFC A;  4C5R A;  1AUW A;  4BAB A;  2QGA B;  3UNV A;  2RJS A;  1RE5 A;  1XWO A;  2O7D A;  4ADL A;  4APB A;  1TJV A;  1Q5N A;  2OHY A;  3R6Q A;  4MX2 A;  3CZO A;  1J3U A;  2HVG A;  2PTR A;  1W27 A;  1YIS A;  1FUP A;  4V2Q A;  4FFX A;  1HY0 A;  2O7F A;  1TJW A;  2O6Y A;  5EYT A;  2E9F A;  2YII A;  2RJR A;  1KQ7 A;  4FLC A;  2O7B A;  4BAA A;  1I0A A;  5D6B A;  3TV2 A;  1GK2 A;  1JSW A;  3OCE A;  2NYN A;  3R6Y A;  1HY1 A;  2O7E A;  3NZ4 A;  1GKM A;  2VD6 A;  1GKJ A;  1T6J A;  2X75 A;  1B8F A;  3QBP A;  1C3C A;  4HGV A;  3E04 A;  1K7W A;  1K62 A;  2FUS A;  3KDZ A;  4CQ5 A;  1U16 A;  2QVE A;  4ADM A;  4C5U A;  4APA A;  1YFM A;  1VDK A;  1C3U A;  1Y2M A;  2J91 A;  1DOF A;  1T6P A;  2PTQ A;  4C6G A;  3BHG A;  3RD8 A;  1GK3 A;  5F92 A;  1FUQ A;  5F91 A;  4C5S A;  5EYV A;  3C8T A;  3NO9 A;  2O78 A;  2NYF A;  2PTS A; 
#chains in the Genus database with same CATH topology
 3U13 A;  1T9H A;  1Z4K A;  1TJU A;  1U15 A;  1EB4 A;  3CRV A;  1XMC A;  4V2R A;  5M0J A;  5HW2 A;  1FUR A;  1Z4I A;  4NLE A;  3GTD A;  4MUM A;  2I7D A;  3KDY A;  1FUO A;  3RRP A;  4L6C A;  4NFL A;  2PFM A;  3R6V A;  1YFE A;  1TJ7 A;  3GZH A;  3OCF A;  4NSL A;  4EEI A;  1DCN A;  4EFC A;  4C5R A;  4MWO A;  2JAU A;  1AUW A;  4IQJ M;  3CI0 K;  4BAB A;  2QGA B;  3UNV A;  5H8W A;  2RJS A;  1RE5 A;  1XWO A;  2O7D A;  2D28 C;  4L6A A;  4ADL A;  4APB A;  1TJV A;  1Q5N A;  2OHY A;  3R6Q A;  4MX2 A;  3CZO A;  1J3U A;  4YIH A;  1U0L A;  2HVG A;  1XL8 A;  2PTR A;  1W27 A;  1YIS A;  1FUP A;  4V2Q A;  4FFX A;  1HY0 A;  2O7F A;  1TJW A;  2O6Y A;  3F4T A;  5EYT A;  2E9F A;  2YII A;  2RJR A;  1KQ7 A;  2FEN A;  4FLC A;  2O7B A;  3U19 A;  4BAA A;  2VSF A;  2YV5 A;  1I0A A;  5D6B A;  3TV2 A;  1GK2 A;  1JSW A;  1Z4Q A;  3OCE A;  2NYN A;  3R6Y A;  1HY1 A;  4YIK A;  1Z4M A;  4L57 A;  2FEL A;  2O7E A;  3NZ4 A;  3CRW 1;  2VL7 A;  1GKM A;  2VD6 A;  1GKJ A;  1T6J A;  2RCN A;  2JAW A;  3F4S A;  2X75 A;  1XL7 A;  1Q92 A;  1B8F A;  5M0I A;  2JAR A;  1Z4P X;  1C3C A;  3QBP A;  2JAO A;  4HGV A;  1XMD A;  3E04 A;  1K7W A;  1K62 A;  2FUS A;  3KDZ A;  4CQ5 A;  1U16 A;  2QVE A;  4ADM A;  4E88 A;  4C5U A;  4APA A;  1YFM A;  1VDK A;  1Z4J A;  1C3U A;  1Y2M A;  2J91 A;  1DOF A;  1Z4L A;  1T6P A;  2PTQ A;  4C6G A;  3F4R A;  3BHG A;  4WNL A;  3RD8 A;  1GK3 A;  5F92 A;  1MH9 A;  1FUQ A;  5F91 A;  2D27 A;  4C5S A;  5EYV A;  3C8T A;  1IW7 D;  1XLY A;  3NO9 A;  2O78 A;  1Q91 A;  2NYF A;  3BWV A;  4A15 A;  2PTS A; 
#chains in the Genus database with same CATH homology
 1TJU A;  1U15 A;  1EB4 A;  4V2R A;  5HW2 A;  1FUR A;  4NLE A;  3GTD A;  3KDY A;  1FUO A;  3RRP A;  3R6V A;  2PFM A;  1YFE A;  1TJ7 A;  3GZH A;  3OCF A;  4NSL A;  4EEI A;  1DCN A;  4EFC A;  4C5R A;  1AUW A;  4BAB A;  2QGA B;  3UNV A;  2RJS A;  1RE5 A;  1XWO A;  2O7D A;  4ADL A;  4APB A;  1TJV A;  1Q5N A;  2OHY A;  3R6Q A;  4MX2 A;  3CZO A;  1J3U A;  2HVG A;  2PTR A;  1W27 A;  1YIS A;  1FUP A;  4V2Q A;  4FFX A;  1HY0 A;  2O7F A;  1TJW A;  2O6Y A;  5EYT A;  2E9F A;  2YII A;  2RJR A;  1KQ7 A;  4FLC A;  2O7B A;  4BAA A;  1I0A A;  5D6B A;  3TV2 A;  1GK2 A;  1JSW A;  3OCE A;  2NYN A;  3R6Y A;  1HY1 A;  2O7E A;  3NZ4 A;  1GKM A;  2VD6 A;  1GKJ A;  1T6J A;  2X75 A;  1B8F A;  3QBP A;  1C3C A;  4HGV A;  3E04 A;  1K7W A;  1K62 A;  2FUS A;  3KDZ A;  4CQ5 A;  1U16 A;  2QVE A;  4ADM A;  4C5U A;  4APA A;  1YFM A;  1VDK A;  1C3U A;  1Y2M A;  2J91 A;  1DOF A;  1T6P A;  2PTQ A;  4C6G A;  3BHG A;  3RD8 A;  1GK3 A;  5F92 A;  1FUQ A;  5F91 A;  4C5S A;  5EYV A;  3C8T A;  3NO9 A;  2O78 A;  2NYF A;  2PTS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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