1GK3A

Histidine ammonia-lyase (hal) mutant d145a from pseudomonas putida
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
509
structure length
509
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGALAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HISTIDINE AMMONIA-LYASE
publication title Autocatalytic Peptide Cyclization During Chain Folding of Histidine Ammonia-Lyase.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
total genus 192
structure length 509
sequence length 509
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gk3A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gk3A02
3RD8A 2E9FA 1T6PA 2O7EA 1K7WA 1KQ7A 4C5SA 1FUOA 1FUPA 2QGAB 4BABA 1U15A 1GK3A 1C3UA 4C5RA 2O6YA 4C6GA 2VD6A 3NZ4A 3E04A 3KDYA 2O7BA 2O7DA 3TV2A 2PTQA 1Y2MA 2NYFA 1J3UA 1K62A 4V2RA 1GKMA 2PFMA 2O78A 1FURA 2RJSA 1RE5A 5HW2A 4APAA 4NLEA 1DCNA 3GZHA 1YISA 3KDZA 1JSWA 2PTSA 5F91A 1TJUA 2HVGA 5F92A 1FUQA 2QVEA 4EFCA 2YIIA 2RJRA 4V2QA 3UNVA 3NO9A 2NYNA 3R6VA 1GK2A 1EB4A 1YFEA 4CQ5A 1GKJA 4APBA 3BHGA 3CZOA 1I0AA 1DOFA 3QBPA 1W27A 1VDKA 2PTRA 2X75A 3GTDA 3OCFA 1U16A 4EEIA 4ADMA 1YFMA 1AUWA 3RRPA 3R6QA 4FLCA 3C8TA 1TJWA 3R6YA 2FUSA 4NSLA 5EYVA 1T6JA 4C5UA 4HGVA 1TJVA 4ADLA 1B8FA 5EYTA 5D6BA 1XWOA 3OCEA 1HY0A 4FFXA 4MX2A 1Q5NA 1C3CA 1HY1A 4BAAA 1TJ7A 2O7FA 2OHYA 2J91A
chains in the Genus database with same CATH superfamily
3RD8A 2E9FA 1T6PA 2O7EA 1K7WA 1KQ7A 4A15A 4C5SA 1FUOA 1FUPA 2QGAB 3CRW1 4BABA 1U15A 1GK3A 1C3UA 4C5RA 4WNLA 1XMDA 2O6YA 4C6GA 2FENA 1XL7A 2VD6A 3NZ4A 3E04A 3KDYA 1XLYA 1XL8A 2O7BA 2O7DA 3TV2A 2VSFA 2PTQA 1Y2MA 2VL7A 2NYFA 1J3UA 1K62A 4V2RA 1GKMA 1XMCA 2PFMA 2O78A 1FURA 2RJSA 1RE5A 5HW2A 4APAA 4NLEA 1DCNA 3GZHA 1YISA 3KDZA 1JSWA 2PTSA 5F91A 1TJUA 2HVGA 5F92A 1FUQA 5M0JA 2QVEA 4EFCA 2YIIA 2RJRA 4V2QA 3UNVA 3NO9A 2NYNA 3R6VA 1GK2A 1EB4A 1YFEA 4CQ5A 1GKJA 4APBA 3BHGA 3CZOA 1I0AA 1DOFA 3QBPA 1W27A 1VDKA 2PTRA 2X75A 3GTDA 3OCFA 1U16A 4EEIA 4ADMA 1YFMA 1AUWA 3RRPA 3R6QA 4FLCA 3C8TA 1TJWA 3R6YA 2FUSA 4NSLA 5EYVA 1T6JA 4C5UA 4HGVA 5M0IA 1TJVA 4ADLA 1B8FA 5EYTA 5D6BA 1XWOA 3OCEA 3CRVA 1HY0A 4FFXA 2FELA 4MX2A 1Q5NA 1C3CA 5H8WA 1HY1A 4BAAA 1TJ7A 2O7FA 2OHYA 2J91A
chains in the Genus database with same CATH topology
3RD8A 2E9FA 1T6PA 2O7EA 1K7WA 1KQ7A 4C5SA 1FUOA 1FUPA 2QGAB 4BABA 1U15A 1GK3A 1C3UA 4C5RA 2O6YA 4C6GA 2VD6A 3NZ4A 3E04A 3KDYA 2O7BA 2O7DA 3TV2A 2PTQA 1Y2MA 2NYFA 1J3UA 1K62A 4V2RA 1GKMA 2PFMA 2O78A 1FURA 2RJSA 1RE5A 5HW2A 4APAA 4NLEA 1DCNA 3GZHA 1YISA 3KDZA 1JSWA 2PTSA 5F91A 1TJUA 2HVGA 5F92A 1FUQA 2QVEA 4EFCA 2YIIA 2RJRA 4V2QA 3UNVA 3NO9A 2NYNA 3R6VA 1GK2A 1EB4A 1YFEA 4CQ5A 1GKJA 4APBA 3BHGA 3CZOA 1I0AA 1DOFA 3QBPA 1W27A 1VDKA 2PTRA 2X75A 3GTDA 3OCFA 1U16A 4EEIA 4ADMA 1YFMA 1AUWA 3RRPA 3R6QA 4FLCA 3C8TA 1TJWA 3R6YA 2FUSA 4NSLA 5EYVA 1T6JA 4C5UA 4HGVA 1TJVA 4ADLA 1B8FA 5EYTA 5D6BA 1XWOA 3OCEA 1HY0A 4FFXA 4MX2A 1Q5NA 1C3CA 1HY1A 4BAAA 1TJ7A 2O7FA 2OHYA 2J91A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RD8 A;  2E9F A;  1T6P A;  2O7E A;  1K7W A;  1KQ7 A;  4C5S A;  1FUO A;  1FUP A;  2QGA B;  4BAB A;  1U15 A;  1GK3 A;  1C3U A;  4C5R A;  2O6Y A;  4C6G A;  2VD6 A;  3NZ4 A;  3E04 A;  3KDY A;  2O7B A;  2O7D A;  3TV2 A;  2PTQ A;  1Y2M A;  2NYF A;  1J3U A;  1K62 A;  4V2R A;  1GKM A;  2PFM A;  2O78 A;  1FUR A;  2RJS A;  1RE5 A;  5HW2 A;  4APA A;  4NLE A;  1DCN A;  3GZH A;  1YIS A;  3KDZ A;  1JSW A;  2PTS A;  5F91 A;  1TJU A;  2HVG A;  5F92 A;  1FUQ A;  2QVE A;  4EFC A;  2YII A;  2RJR A;  4V2Q A;  3UNV A;  3NO9 A;  2NYN A;  3R6V A;  1GK2 A;  1EB4 A;  1YFE A;  4CQ5 A;  1GKJ A;  4APB A;  3BHG A;  3CZO A;  1I0A A;  1DOF A;  3QBP A;  1W27 A;  1VDK A;  2PTR A;  2X75 A;  3GTD A;  3OCF A;  1U16 A;  4EEI A;  4ADM A;  1YFM A;  1AUW A;  3RRP A;  3R6Q A;  4FLC A;  3C8T A;  1TJW A;  3R6Y A;  2FUS A;  4NSL A;  5EYV A;  1T6J A;  4C5U A;  4HGV A;  1TJV A;  4ADL A;  1B8F A;  5EYT A;  5D6B A;  1XWO A;  3OCE A;  1HY0 A;  4FFX A;  4MX2 A;  1Q5N A;  1C3C A;  1HY1 A;  4BAA A;  1TJ7 A;  2O7F A;  2OHY A;  2J91 A; 
#chains in the Genus database with same CATH topology
 3RD8 A;  2E9F A;  1T6P A;  2O7E A;  1K7W A;  1KQ7 A;  4A15 A;  4C5S A;  1FUO A;  1FUP A;  2QGA B;  3CRW 1;  4BAB A;  1U15 A;  1GK3 A;  1C3U A;  4C5R A;  4WNL A;  1XMD A;  2O6Y A;  4C6G A;  2FEN A;  1XL7 A;  2VD6 A;  3NZ4 A;  3E04 A;  3KDY A;  1XLY A;  1XL8 A;  2O7B A;  2O7D A;  3TV2 A;  2VSF A;  2PTQ A;  1Y2M A;  2VL7 A;  2NYF A;  1J3U A;  1K62 A;  4V2R A;  1GKM A;  1XMC A;  2PFM A;  2O78 A;  1FUR A;  2RJS A;  1RE5 A;  5HW2 A;  4APA A;  4NLE A;  1DCN A;  3GZH A;  1YIS A;  3KDZ A;  1JSW A;  2PTS A;  5F91 A;  1TJU A;  2HVG A;  5F92 A;  1FUQ A;  5M0J A;  2QVE A;  4EFC A;  2YII A;  2RJR A;  4V2Q A;  3UNV A;  3NO9 A;  2NYN A;  3R6V A;  1GK2 A;  1EB4 A;  1YFE A;  4CQ5 A;  1GKJ A;  4APB A;  3BHG A;  3CZO A;  1I0A A;  1DOF A;  3QBP A;  1W27 A;  1VDK A;  2PTR A;  2X75 A;  3GTD A;  3OCF A;  1U16 A;  4EEI A;  4ADM A;  1YFM A;  1AUW A;  3RRP A;  3R6Q A;  4FLC A;  3C8T A;  1TJW A;  3R6Y A;  2FUS A;  4NSL A;  5EYV A;  1T6J A;  4C5U A;  4HGV A;  5M0I A;  1TJV A;  4ADL A;  1B8F A;  5EYT A;  5D6B A;  1XWO A;  3OCE A;  3CRV A;  1HY0 A;  4FFX A;  2FEL A;  4MX2 A;  1Q5N A;  1C3C A;  5H8W A;  1HY1 A;  4BAA A;  1TJ7 A;  2O7F A;  2OHY A;  2J91 A; 
#chains in the Genus database with same CATH homology
 3RD8 A;  2E9F A;  1T6P A;  2O7E A;  1K7W A;  1KQ7 A;  4C5S A;  1FUO A;  1FUP A;  2QGA B;  4BAB A;  1U15 A;  1GK3 A;  1C3U A;  4C5R A;  2O6Y A;  4C6G A;  2VD6 A;  3NZ4 A;  3E04 A;  3KDY A;  2O7B A;  2O7D A;  3TV2 A;  2PTQ A;  1Y2M A;  2NYF A;  1J3U A;  1K62 A;  4V2R A;  1GKM A;  2PFM A;  2O78 A;  1FUR A;  2RJS A;  1RE5 A;  5HW2 A;  4APA A;  4NLE A;  1DCN A;  3GZH A;  1YIS A;  3KDZ A;  1JSW A;  2PTS A;  5F91 A;  1TJU A;  2HVG A;  5F92 A;  1FUQ A;  2QVE A;  4EFC A;  2YII A;  2RJR A;  4V2Q A;  3UNV A;  3NO9 A;  2NYN A;  3R6V A;  1GK2 A;  1EB4 A;  1YFE A;  4CQ5 A;  1GKJ A;  4APB A;  3BHG A;  3CZO A;  1I0A A;  1DOF A;  3QBP A;  1W27 A;  1VDK A;  2PTR A;  2X75 A;  3GTD A;  3OCF A;  1U16 A;  4EEI A;  4ADM A;  1YFM A;  1AUW A;  3RRP A;  3R6Q A;  4FLC A;  3C8T A;  1TJW A;  3R6Y A;  2FUS A;  4NSL A;  5EYV A;  1T6J A;  4C5U A;  4HGV A;  1TJV A;  4ADL A;  1B8F A;  5EYT A;  5D6B A;  1XWO A;  3OCE A;  1HY0 A;  4FFX A;  4MX2 A;  1Q5N A;  1C3C A;  1HY1 A;  4BAA A;  1TJ7 A;  2O7F A;  2OHY A;  2J91 A; 
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similar chains in the Genus database (?% sequence similarity)
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