1GK3A

Histidine ammonia-lyase (hal) mutant d145a from pseudomonas putida
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
509
structure length
509
Chain Sequence
b'TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGALAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HISTIDINE AMMONIA-LYASE
publication title Autocatalytic Peptide Cyclization During Chain Folding of Histidine Ammonia-Lyase.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
total genus 192
structure length 509
sequence length 509
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gk3A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gk3A02
2FUSA 2PTSA 3KDZA 4APBA 1T6JA 5EYTA 5F91A 3R6QA 2VD6A 1YFEA 3UNVA 1EB4A 5EYVA 4HGVA 1TJUA 2O7BA 4ADLA 4C5UA 1JSWA 4NSLA 2O6YA 1Y2MA 2HVGA 2NYFA 1W27A 4ADMA 4FLCA 1T6PA 2PTQA 2J91A 2QVEA 4MX2A 5HW2A 2X75A 1FURA 1GK3A 2QGAB 3BHGA 1FUQA 1B8FA 3GTDA 3RD8A 2E9FA 3NO9A 1AUWA 1K7WA 1FUOA 3GZHA 2OHYA 1HY0A 1YFMA 1Q5NA 2PTRA 1TJWA 3R6VA 1YISA 4BAAA 4FFXA 1TJ7A 3RRPA 3C8TA 1I0AA 1K62A 2O7DA 4EEIA 3OCFA 3QBPA 4NLEA 1DCNA 2RJSA 1C3CA 2YIIA 3CZOA 3OCEA 1C3UA 2O7EA 2O7FA 1U16A 1DOFA 2PFMA 1GK2A 4C6GA 3NZ4A 2RJRA 4V2QA 1J3UA 1FUPA 3R6YA 1TJVA 3KDYA 2O78A 5D6BA 4EFCA 4C5SA 4APAA 1GKMA 3TV2A 1XWOA 1GKJA 5F92A 4C5RA 3E04A 4V2RA 1VDKA 4BABA 2NYNA 1KQ7A 4CQ5A 1HY1A 1U15A 1RE5A
chains in the Genus database with same CATH superfamily
2FUSA 2PTSA 3KDZA 4APBA 1T6JA 5EYTA 1XL8A 5F91A 3R6QA 2VD6A 1YFEA 3UNVA 1EB4A 1XMCA 5EYVA 4HGVA 1TJUA 2O7BA 4ADLA 3CRVA 4C5UA 1JSWA 2VSFA 4NSLA 4WNLA 2O6YA 1Y2MA 2HVGA 3CRW1 2NYFA 1W27A 4ADMA 4FLCA 1T6PA 2PTQA 2J91A 1XLYA 2QVEA 4MX2A 5HW2A 2X75A 1FURA 1GK3A 2QGAB 3BHGA 1FUQA 1B8FA 3GTDA 3RD8A 2E9FA 3NO9A 1AUWA 2FELA 1K7WA 1FUOA 3GZHA 5H8WA 2OHYA 1HY0A 1YFMA 1Q5NA 2PTRA 1TJWA 3R6VA 1YISA 4BAAA 4FFXA 1TJ7A 3RRPA 3C8TA 1I0AA 1K62A 2O7DA 4EEIA 3OCFA 3QBPA 4NLEA 1DCNA 2RJSA 1XL7A 1C3CA 2YIIA 3CZOA 3OCEA 1C3UA 2O7EA 2O7FA 1U16A 1DOFA 2PFMA 1GK2A 4C6GA 3NZ4A 2RJRA 4V2QA 1J3UA 1FUPA 2FENA 2VL7A 3R6YA 1TJVA 3KDYA 2O78A 5D6BA 4EFCA 4C5SA 4APAA 1GKMA 3TV2A 1XWOA 4A15A 1GKJA 5F92A 4C5RA 3E04A 5M0IA 5M0JA 4V2RA 1VDKA 4BABA 2NYNA 1KQ7A 4CQ5A 1XMDA 1HY1A 1U15A 1RE5A
chains in the Genus database with same CATH topology
2FUSA 2PTSA 3KDZA 4APBA 1T6JA 5EYTA 5F91A 3R6QA 2VD6A 1YFEA 3UNVA 1EB4A 5EYVA 4HGVA 1TJUA 2O7BA 4ADLA 4C5UA 1JSWA 4NSLA 2O6YA 1Y2MA 2HVGA 2NYFA 1W27A 4ADMA 4FLCA 1T6PA 2PTQA 2J91A 2QVEA 4MX2A 5HW2A 2X75A 1FURA 1GK3A 2QGAB 3BHGA 1FUQA 1B8FA 3GTDA 3RD8A 2E9FA 3NO9A 1AUWA 1K7WA 1FUOA 3GZHA 2OHYA 1HY0A 1YFMA 1Q5NA 2PTRA 1TJWA 3R6VA 1YISA 4BAAA 4FFXA 1TJ7A 3RRPA 3C8TA 1I0AA 1K62A 2O7DA 4EEIA 3OCFA 3QBPA 4NLEA 1DCNA 2RJSA 1C3CA 2YIIA 3CZOA 3OCEA 1C3UA 2O7EA 2O7FA 1U16A 1DOFA 2PFMA 1GK2A 4C6GA 3NZ4A 2RJRA 4V2QA 1J3UA 1FUPA 3R6YA 1TJVA 3KDYA 2O78A 5D6BA 4EFCA 4C5SA 4APAA 1GKMA 3TV2A 1XWOA 1GKJA 5F92A 4C5RA 3E04A 4V2RA 1VDKA 4BABA 2NYNA 1KQ7A 4CQ5A 1HY1A 1U15A 1RE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FUS A;  2PTS A;  3KDZ A;  4APB A;  1T6J A;  5EYT A;  5F91 A;  3R6Q A;  2VD6 A;  1YFE A;  3UNV A;  1EB4 A;  5EYV A;  4HGV A;  1TJU A;  2O7B A;  4ADL A;  4C5U A;  1JSW A;  4NSL A;  2O6Y A;  1Y2M A;  2HVG A;  2NYF A;  1W27 A;  4ADM A;  4FLC A;  1T6P A;  2PTQ A;  2J91 A;  2QVE A;  4MX2 A;  5HW2 A;  2X75 A;  1FUR A;  1GK3 A;  2QGA B;  3BHG A;  1FUQ A;  1B8F A;  3GTD A;  3RD8 A;  2E9F A;  3NO9 A;  1AUW A;  1K7W A;  1FUO A;  3GZH A;  2OHY A;  1HY0 A;  1YFM A;  1Q5N A;  2PTR A;  1TJW A;  3R6V A;  1YIS A;  4BAA A;  4FFX A;  1TJ7 A;  3RRP A;  3C8T A;  1I0A A;  1K62 A;  2O7D A;  4EEI A;  3OCF A;  3QBP A;  4NLE A;  1DCN A;  2RJS A;  1C3C A;  2YII A;  3CZO A;  3OCE A;  1C3U A;  2O7E A;  2O7F A;  1U16 A;  1DOF A;  2PFM A;  1GK2 A;  4C6G A;  3NZ4 A;  2RJR A;  4V2Q A;  1J3U A;  1FUP A;  3R6Y A;  1TJV A;  3KDY A;  2O78 A;  5D6B A;  4EFC A;  4C5S A;  4APA A;  1GKM A;  3TV2 A;  1XWO A;  1GKJ A;  5F92 A;  4C5R A;  3E04 A;  4V2R A;  1VDK A;  4BAB A;  2NYN A;  1KQ7 A;  4CQ5 A;  1HY1 A;  1U15 A;  1RE5 A; 
#chains in the Genus database with same CATH topology
 2FUS A;  2PTS A;  3KDZ A;  4APB A;  1T6J A;  5EYT A;  1XL8 A;  5F91 A;  3R6Q A;  2VD6 A;  1YFE A;  3UNV A;  1EB4 A;  1XMC A;  5EYV A;  4HGV A;  1TJU A;  2O7B A;  4ADL A;  3CRV A;  4C5U A;  1JSW A;  2VSF A;  4NSL A;  4WNL A;  2O6Y A;  1Y2M A;  2HVG A;  3CRW 1;  2NYF A;  1W27 A;  4ADM A;  4FLC A;  1T6P A;  2PTQ A;  2J91 A;  1XLY A;  2QVE A;  4MX2 A;  5HW2 A;  2X75 A;  1FUR A;  1GK3 A;  2QGA B;  3BHG A;  1FUQ A;  1B8F A;  3GTD A;  3RD8 A;  2E9F A;  3NO9 A;  1AUW A;  2FEL A;  1K7W A;  1FUO A;  3GZH A;  5H8W A;  2OHY A;  1HY0 A;  1YFM A;  1Q5N A;  2PTR A;  1TJW A;  3R6V A;  1YIS A;  4BAA A;  4FFX A;  1TJ7 A;  3RRP A;  3C8T A;  1I0A A;  1K62 A;  2O7D A;  4EEI A;  3OCF A;  3QBP A;  4NLE A;  1DCN A;  2RJS A;  1XL7 A;  1C3C A;  2YII A;  3CZO A;  3OCE A;  1C3U A;  2O7E A;  2O7F A;  1U16 A;  1DOF A;  2PFM A;  1GK2 A;  4C6G A;  3NZ4 A;  2RJR A;  4V2Q A;  1J3U A;  1FUP A;  2FEN A;  2VL7 A;  3R6Y A;  1TJV A;  3KDY A;  2O78 A;  5D6B A;  4EFC A;  4C5S A;  4APA A;  1GKM A;  3TV2 A;  1XWO A;  4A15 A;  1GKJ A;  5F92 A;  4C5R A;  3E04 A;  5M0I A;  5M0J A;  4V2R A;  1VDK A;  4BAB A;  2NYN A;  1KQ7 A;  4CQ5 A;  1XMD A;  1HY1 A;  1U15 A;  1RE5 A; 
#chains in the Genus database with same CATH homology
 2FUS A;  2PTS A;  3KDZ A;  4APB A;  1T6J A;  5EYT A;  5F91 A;  3R6Q A;  2VD6 A;  1YFE A;  3UNV A;  1EB4 A;  5EYV A;  4HGV A;  1TJU A;  2O7B A;  4ADL A;  4C5U A;  1JSW A;  4NSL A;  2O6Y A;  1Y2M A;  2HVG A;  2NYF A;  1W27 A;  4ADM A;  4FLC A;  1T6P A;  2PTQ A;  2J91 A;  2QVE A;  4MX2 A;  5HW2 A;  2X75 A;  1FUR A;  1GK3 A;  2QGA B;  3BHG A;  1FUQ A;  1B8F A;  3GTD A;  3RD8 A;  2E9F A;  3NO9 A;  1AUW A;  1K7W A;  1FUO A;  3GZH A;  2OHY A;  1HY0 A;  1YFM A;  1Q5N A;  2PTR A;  1TJW A;  3R6V A;  1YIS A;  4BAA A;  4FFX A;  1TJ7 A;  3RRP A;  3C8T A;  1I0A A;  1K62 A;  2O7D A;  4EEI A;  3OCF A;  3QBP A;  4NLE A;  1DCN A;  2RJS A;  1C3C A;  2YII A;  3CZO A;  3OCE A;  1C3U A;  2O7E A;  2O7F A;  1U16 A;  1DOF A;  2PFM A;  1GK2 A;  4C6G A;  3NZ4 A;  2RJR A;  4V2Q A;  1J3U A;  1FUP A;  3R6Y A;  1TJV A;  3KDY A;  2O78 A;  5D6B A;  4EFC A;  4C5S A;  4APA A;  1GKM A;  3TV2 A;  1XWO A;  1GKJ A;  5F92 A;  4C5R A;  3E04 A;  4V2R A;  1VDK A;  4BAB A;  2NYN A;  1KQ7 A;  4CQ5 A;  1HY1 A;  1U15 A;  1RE5 A; 
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