1GK3A

Histidine ammonia-lyase (hal) mutant d145a from pseudomonas putida
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
509
structure length
509
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGALAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Autocatalytic Peptide Cyclization During Chain Folding of Histidine Ammonia-Lyase.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
molecule keywords HISTIDINE AMMONIA-LYASE
total genus 192
structure length 509
sequence length 509
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gk3A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gk3A02
1GKMA 4C5UA 3OCFA 4BAAA 1I0AA 2J91A 1YFEA 2RJRA 1Y2MA 5EYTA 3KDZA 2PTQA 1HY1A 1FUPA 3RRPA 5HW2A 1FURA 1GK2A 3UNVA 3CZOA 1FUOA 2O7FA 2FUSA 4MX2A 4APAA 1TJ7A 2O7BA 2O7EA 2RJSA 2O7DA 1TJWA 2HVGA 3GTDA 3R6YA 4EFCA 4V2RA 4CQ5A 1T6PA 5F92A 1JSWA 2YIIA 4C6GA 4C5SA 4EEIA 4V2QA 1B8FA 5EYVA 4ADMA 1W27A 1TJUA 1U15A 2X75A 1T6JA 1C3UA 1GK3A 3NO9A 1TJVA 2PTSA 3E04A 3KDYA 1HY0A 1DCNA 4NSLA 2OHYA 1EB4A 3QBPA 1DOFA 1AUWA 1Q5NA 4FLCA 4APBA 3GZHA 2O6YA 3BHGA 3RD8A 2PFMA 3NZ4A 1VDKA 1YISA 2PTRA 2NYNA 4C5RA 3OCEA 1YFMA 1K62A 4ADLA 4HGVA 2E9FA 1GKJA 4FFXA 1RE5A 2QVEA 4NLEA 2QGAB 2VD6A 5F91A 1U16A 5D6BA 1J3UA 3C8TA 1KQ7A 3R6QA 4BABA 3R6VA 1K7WA 2O78A 1XWOA 2NYFA 1C3CA 3TV2A 1FUQA
chains in the Genus database with same CATH superfamily
1GKMA 4C5UA 3OCFA 4BAAA 1I0AA 1XMCA 2J91A 1YFEA 2RJRA 1Y2MA 5EYTA 3KDZA 2PTQA 1HY1A 4A15A 1FUPA 3RRPA 2VSFA 1FURA 1GK2A 3UNVA 5HW2A 3CZOA 1FUOA 2O7FA 5M0IA 2FUSA 4MX2A 5M0JA 4APAA 1TJ7A 2O7BA 2O7EA 2RJSA 2O7DA 1TJWA 2HVGA 3GTDA 3R6YA 4WNLA 4EFCA 4V2RA 4CQ5A 1T6PA 5F92A 1JSWA 2YIIA 4C6GA 4C5SA 4EEIA 1XL7A 4V2QA 1B8FA 5EYVA 4ADMA 1W27A 1TJUA 1U15A 2X75A 1T6JA 1C3UA 1XMDA 1GK3A 3NO9A 1TJVA 1XL8A 2PTSA 3E04A 1XLYA 2FENA 3KDYA 2VL7A 1HY0A 1DCNA 3CRVA 4NSLA 2OHYA 1EB4A 3QBPA 1DOFA 1AUWA 1Q5NA 4FLCA 5H8WA 4APBA 3GZHA 2O6YA 3BHGA 3RD8A 2PFMA 3NZ4A 1VDKA 1YISA 2PTRA 2NYNA 4C5RA 3OCEA 1YFMA 1K62A 4ADLA 4HGVA 2E9FA 1GKJA 4FFXA 1RE5A 2QVEA 4NLEA 2QGAB 2VD6A 5F91A 1U16A 5D6BA 1J3UA 3C8TA 3CRW1 1KQ7A 3R6QA 4BABA 3R6VA 1K7WA 2O78A 1XWOA 2FELA 2NYFA 1C3CA 3TV2A 1FUQA
chains in the Genus database with same CATH topology
1GKMA 4C5UA 3OCFA 4BAAA 1I0AA 2J91A 1YFEA 2RJRA 1Y2MA 5EYTA 3KDZA 2PTQA 1HY1A 1FUPA 3RRPA 5HW2A 1FURA 1GK2A 3UNVA 3CZOA 1FUOA 2O7FA 2FUSA 4MX2A 4APAA 1TJ7A 2O7BA 2O7EA 2RJSA 2O7DA 1TJWA 2HVGA 3GTDA 3R6YA 4EFCA 4V2RA 4CQ5A 1T6PA 5F92A 1JSWA 2YIIA 4C6GA 4C5SA 4EEIA 4V2QA 1B8FA 5EYVA 4ADMA 1W27A 1TJUA 1U15A 2X75A 1T6JA 1C3UA 1GK3A 3NO9A 1TJVA 2PTSA 3E04A 3KDYA 1HY0A 1DCNA 4NSLA 2OHYA 1EB4A 3QBPA 1DOFA 1AUWA 1Q5NA 4FLCA 4APBA 3GZHA 2O6YA 3BHGA 3RD8A 2PFMA 3NZ4A 1VDKA 1YISA 2PTRA 2NYNA 4C5RA 3OCEA 1YFMA 1K62A 4ADLA 4HGVA 2E9FA 1GKJA 4FFXA 1RE5A 2QVEA 4NLEA 2QGAB 2VD6A 5F91A 1U16A 5D6BA 1J3UA 3C8TA 1KQ7A 3R6QA 4BABA 3R6VA 1K7WA 2O78A 1XWOA 2NYFA 1C3CA 3TV2A 1FUQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKM A;  4C5U A;  3OCF A;  4BAA A;  1I0A A;  2J91 A;  1YFE A;  2RJR A;  1Y2M A;  5EYT A;  3KDZ A;  2PTQ A;  1HY1 A;  1FUP A;  3RRP A;  5HW2 A;  1FUR A;  1GK2 A;  3UNV A;  3CZO A;  1FUO A;  2O7F A;  2FUS A;  4MX2 A;  4APA A;  1TJ7 A;  2O7B A;  2O7E A;  2RJS A;  2O7D A;  1TJW A;  2HVG A;  3GTD A;  3R6Y A;  4EFC A;  4V2R A;  4CQ5 A;  1T6P A;  5F92 A;  1JSW A;  2YII A;  4C6G A;  4C5S A;  4EEI A;  4V2Q A;  1B8F A;  5EYV A;  4ADM A;  1W27 A;  1TJU A;  1U15 A;  2X75 A;  1T6J A;  1C3U A;  1GK3 A;  3NO9 A;  1TJV A;  2PTS A;  3E04 A;  3KDY A;  1HY0 A;  1DCN A;  4NSL A;  2OHY A;  1EB4 A;  3QBP A;  1DOF A;  1AUW A;  1Q5N A;  4FLC A;  4APB A;  3GZH A;  2O6Y A;  3BHG A;  3RD8 A;  2PFM A;  3NZ4 A;  1VDK A;  1YIS A;  2PTR A;  2NYN A;  4C5R A;  3OCE A;  1YFM A;  1K62 A;  4ADL A;  4HGV A;  2E9F A;  1GKJ A;  4FFX A;  1RE5 A;  2QVE A;  4NLE A;  2QGA B;  2VD6 A;  5F91 A;  1U16 A;  5D6B A;  1J3U A;  3C8T A;  1KQ7 A;  3R6Q A;  4BAB A;  3R6V A;  1K7W A;  2O78 A;  1XWO A;  2NYF A;  1C3C A;  3TV2 A;  1FUQ A; 
#chains in the Genus database with same CATH topology
 1GKM A;  4C5U A;  3OCF A;  4BAA A;  1I0A A;  1XMC A;  2J91 A;  1YFE A;  2RJR A;  1Y2M A;  5EYT A;  3KDZ A;  2PTQ A;  1HY1 A;  4A15 A;  1FUP A;  3RRP A;  2VSF A;  1FUR A;  1GK2 A;  3UNV A;  5HW2 A;  3CZO A;  1FUO A;  2O7F A;  5M0I A;  2FUS A;  4MX2 A;  5M0J A;  4APA A;  1TJ7 A;  2O7B A;  2O7E A;  2RJS A;  2O7D A;  1TJW A;  2HVG A;  3GTD A;  3R6Y A;  4WNL A;  4EFC A;  4V2R A;  4CQ5 A;  1T6P A;  5F92 A;  1JSW A;  2YII A;  4C6G A;  4C5S A;  4EEI A;  1XL7 A;  4V2Q A;  1B8F A;  5EYV A;  4ADM A;  1W27 A;  1TJU A;  1U15 A;  2X75 A;  1T6J A;  1C3U A;  1XMD A;  1GK3 A;  3NO9 A;  1TJV A;  1XL8 A;  2PTS A;  3E04 A;  1XLY A;  2FEN A;  3KDY A;  2VL7 A;  1HY0 A;  1DCN A;  3CRV A;  4NSL A;  2OHY A;  1EB4 A;  3QBP A;  1DOF A;  1AUW A;  1Q5N A;  4FLC A;  5H8W A;  4APB A;  3GZH A;  2O6Y A;  3BHG A;  3RD8 A;  2PFM A;  3NZ4 A;  1VDK A;  1YIS A;  2PTR A;  2NYN A;  4C5R A;  3OCE A;  1YFM A;  1K62 A;  4ADL A;  4HGV A;  2E9F A;  1GKJ A;  4FFX A;  1RE5 A;  2QVE A;  4NLE A;  2QGA B;  2VD6 A;  5F91 A;  1U16 A;  5D6B A;  1J3U A;  3C8T A;  3CRW 1;  1KQ7 A;  3R6Q A;  4BAB A;  3R6V A;  1K7W A;  2O78 A;  1XWO A;  2FEL A;  2NYF A;  1C3C A;  3TV2 A;  1FUQ A; 
#chains in the Genus database with same CATH homology
 1GKM A;  4C5U A;  3OCF A;  4BAA A;  1I0A A;  2J91 A;  1YFE A;  2RJR A;  1Y2M A;  5EYT A;  3KDZ A;  2PTQ A;  1HY1 A;  1FUP A;  3RRP A;  5HW2 A;  1FUR A;  1GK2 A;  3UNV A;  3CZO A;  1FUO A;  2O7F A;  2FUS A;  4MX2 A;  4APA A;  1TJ7 A;  2O7B A;  2O7E A;  2RJS A;  2O7D A;  1TJW A;  2HVG A;  3GTD A;  3R6Y A;  4EFC A;  4V2R A;  4CQ5 A;  1T6P A;  5F92 A;  1JSW A;  2YII A;  4C6G A;  4C5S A;  4EEI A;  4V2Q A;  1B8F A;  5EYV A;  4ADM A;  1W27 A;  1TJU A;  1U15 A;  2X75 A;  1T6J A;  1C3U A;  1GK3 A;  3NO9 A;  1TJV A;  2PTS A;  3E04 A;  3KDY A;  1HY0 A;  1DCN A;  4NSL A;  2OHY A;  1EB4 A;  3QBP A;  1DOF A;  1AUW A;  1Q5N A;  4FLC A;  4APB A;  3GZH A;  2O6Y A;  3BHG A;  3RD8 A;  2PFM A;  3NZ4 A;  1VDK A;  1YIS A;  2PTR A;  2NYN A;  4C5R A;  3OCE A;  1YFM A;  1K62 A;  4ADL A;  4HGV A;  2E9F A;  1GKJ A;  4FFX A;  1RE5 A;  2QVE A;  4NLE A;  2QGA B;  2VD6 A;  5F91 A;  1U16 A;  5D6B A;  1J3U A;  3C8T A;  1KQ7 A;  3R6Q A;  4BAB A;  3R6V A;  1K7W A;  2O78 A;  1XWO A;  2NYF A;  1C3C A;  3TV2 A;  1FUQ A; 
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similar chains in the Genus database (?% sequence similarity)
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