1C3CA

T. maritima adenylosuccinate lyase
Total Genus 171
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
171
sequence length
429
structure length
424
Chain Sequence
b'VERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEK'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PROTEIN (ADENYLOSUCCINATE LYASE)
publication title The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase
total genus 171
structure length 424
sequence length 429
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 1999-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1c3cA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1c3cA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1c3cA02
3OCFA 2QGAB 1Y2MA 1DCNA 4HGVA 4APAA 3KDYA 4C6GA 2RJSA 1HY1A 1FUQA 4BABA 2E9FA 3RD8A 2PTSA 4MX2A 3NZ4A 1C3CA 1GKJA 1KQ7A 4ADMA 1T6JA 1J3UA 5EYVA 4NLEA 3OCEA 1XWOA 3BHGA 4APBA 2YIIA 1TJVA 3GTDA 1GKMA 1GK3A 4C5UA 1K62A 2O7EA 4BAAA 4V2RA 2NYNA 1AUWA 4EEIA 3UNVA 3KDZA 1HY0A 2O7DA 1K7WA 1TJWA 1YFMA 1W27A 1Q5NA 5EYTA 1T6PA 1TJUA 4FLCA 1FUOA 3RRPA 3R6QA 3R6VA 4EFCA 3QBPA 1FUPA 3TV2A 2J91A 2PFMA 4C5RA 1U16A 4V2QA 1B8FA 1VDKA 2O7FA 2O78A 1EB4A 4ADLA 2HVGA 1C3UA 2PTRA 4CQ5A 2VD6A 1TJ7A 1DOFA 2O6YA 3E04A 3CZOA 3GZHA 1YISA 2FUSA 3NO9A 4NSLA 5HW2A 2NYFA 1I0AA 2PTQA 3R6YA 2X75A 5D6BA 1FURA 2QVEA 1JSWA 1U15A 5F91A 2RJRA 1YFEA 2O7BA 5F92A 2OHYA 4FFXA 1GK2A 1RE5A 3C8TA 4C5SA
chains in the Genus database with same CATH superfamily
3OCFA 2QGAB 1Y2MA 1DCNA 3BWVA 4HGVA 3CI0K 4APAA 5M0JA 3KDYA 4C6GA 2RJSA 1HY1A 4L6AA 3F4SA 1FUQA 1Z4JA 4BABA 3U13A 1T9HA 2E9FA 3RD8A 2PTSA 2I7DA 4L57A 4MX2A 3NZ4A 1C3CA 1GKJA 4WNLA 2FELA 3CRVA 1KQ7A 4ADMA 1T6JA 2D27A 1J3UA 5EYVA 4NLEA 3OCEA 1XWOA 3BHGA 4APBA 2YIIA 1TJVA 3GTDA 1GKMA 1U0LA 1XMDA 1XMCA 1GK3A 4A15A 4C5UA 1K62A 2O7EA 4BAAA 4V2RA 2NYNA 3CRW1 2YV5A 1AUWA 4IQJM 4MUMA 4EEIA 1Z4MA 3UNVA 3KDZA 1HY0A 1Q92A 1K7WA 2O7DA 1TJWA 1YFMA 1W27A 1Z4KA 1Q5NA 5H8WA 5EYTA 1T6PA 1TJUA 4FLCA 1FUOA 3RRPA 2JAWA 3R6QA 1XL7A 3R6VA 4EFCA 3QBPA 1FUPA 2RCNA 3TV2A 4E88A 2J91A 4L6CA 2PFMA 4C5RA 1U16A 1Z4PX 4YIHA 4V2QA 3F4RA 1B8FA 1VDKA 2O7FA 2O78A 2VSFA 1IW7D 2D28C 1EB4A 4ADLA 2HVGA 1C3UA 1MH9A 2PTRA 4CQ5A 2VD6A 1Z4IA 2VL7A 1TJ7A 1Z4QA 1DOFA 2O6YA 3E04A 3CZOA 3GZHA 1XLYA 4MWOA 4YIKA 1YISA 2FENA 2FUSA 3NO9A 4NSLA 2JAUA 5HW2A 2JAOA 1XL8A 1I0AA 2NYFA 2PTQA 3R6YA 2X75A 5D6BA 1FURA 2QVEA 3F4TA 5M0IA 1JSWA 1U15A 5F91A 2RJRA 1YFEA 2O7BA 3U19A 5F92A 1Z4LA 2OHYA 4FFXA 1GK2A 1Q91A 1RE5A 4NFLA 3C8TA 4C5SA 2JARA
chains in the Genus database with same CATH topology
3OCFA 2QGAB 1Y2MA 1DCNA 4HGVA 4APAA 3KDYA 4C6GA 2RJSA 1HY1A 1FUQA 4BABA 2E9FA 3RD8A 2PTSA 4MX2A 3NZ4A 1C3CA 1GKJA 1KQ7A 4ADMA 1T6JA 1J3UA 5EYVA 4NLEA 3OCEA 1XWOA 3BHGA 4APBA 2YIIA 1TJVA 3GTDA 1GKMA 1GK3A 4C5UA 1K62A 2O7EA 4BAAA 4V2RA 2NYNA 1AUWA 4EEIA 3UNVA 3KDZA 1HY0A 2O7DA 1K7WA 1TJWA 1YFMA 1W27A 1Q5NA 5EYTA 1T6PA 1TJUA 4FLCA 1FUOA 3RRPA 3R6QA 3R6VA 4EFCA 3QBPA 1FUPA 3TV2A 2J91A 2PFMA 4C5RA 1U16A 4V2QA 1B8FA 1VDKA 2O7FA 2O78A 1EB4A 4ADLA 2HVGA 1C3UA 2PTRA 4CQ5A 2VD6A 1TJ7A 1DOFA 2O6YA 3E04A 3CZOA 3GZHA 1YISA 2FUSA 3NO9A 4NSLA 5HW2A 2NYFA 1I0AA 2PTQA 3R6YA 2X75A 5D6BA 1FURA 2QVEA 1JSWA 1U15A 5F91A 2RJRA 1YFEA 2O7BA 5F92A 2OHYA 4FFXA 1GK2A 1RE5A 3C8TA 4C5SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OCF A;  2QGA B;  1Y2M A;  1DCN A;  4HGV A;  4APA A;  3KDY A;  4C6G A;  2RJS A;  1HY1 A;  1FUQ A;  4BAB A;  2E9F A;  3RD8 A;  2PTS A;  4MX2 A;  3NZ4 A;  1C3C A;  1GKJ A;  1KQ7 A;  4ADM A;  1T6J A;  1J3U A;  5EYV A;  4NLE A;  3OCE A;  1XWO A;  3BHG A;  4APB A;  2YII A;  1TJV A;  3GTD A;  1GKM A;  1GK3 A;  4C5U A;  1K62 A;  2O7E A;  4BAA A;  4V2R A;  2NYN A;  1AUW A;  4EEI A;  3UNV A;  3KDZ A;  1HY0 A;  2O7D A;  1K7W A;  1TJW A;  1YFM A;  1W27 A;  1Q5N A;  5EYT A;  1T6P A;  1TJU A;  4FLC A;  1FUO A;  3RRP A;  3R6Q A;  3R6V A;  4EFC A;  3QBP A;  1FUP A;  3TV2 A;  2J91 A;  2PFM A;  4C5R A;  1U16 A;  4V2Q A;  1B8F A;  1VDK A;  2O7F A;  2O78 A;  1EB4 A;  4ADL A;  2HVG A;  1C3U A;  2PTR A;  4CQ5 A;  2VD6 A;  1TJ7 A;  1DOF A;  2O6Y A;  3E04 A;  3CZO A;  3GZH A;  1YIS A;  2FUS A;  3NO9 A;  4NSL A;  5HW2 A;  2NYF A;  1I0A A;  2PTQ A;  3R6Y A;  2X75 A;  5D6B A;  1FUR A;  2QVE A;  1JSW A;  1U15 A;  5F91 A;  2RJR A;  1YFE A;  2O7B A;  5F92 A;  2OHY A;  4FFX A;  1GK2 A;  1RE5 A;  3C8T A;  4C5S A; 
#chains in the Genus database with same CATH topology
 3OCF A;  2QGA B;  1Y2M A;  1DCN A;  3BWV A;  4HGV A;  3CI0 K;  4APA A;  5M0J A;  3KDY A;  4C6G A;  2RJS A;  1HY1 A;  4L6A A;  3F4S A;  1FUQ A;  1Z4J A;  4BAB A;  3U13 A;  1T9H A;  2E9F A;  3RD8 A;  2PTS A;  2I7D A;  4L57 A;  4MX2 A;  3NZ4 A;  1C3C A;  1GKJ A;  4WNL A;  2FEL A;  3CRV A;  1KQ7 A;  4ADM A;  1T6J A;  2D27 A;  1J3U A;  5EYV A;  4NLE A;  3OCE A;  1XWO A;  3BHG A;  4APB A;  2YII A;  1TJV A;  3GTD A;  1GKM A;  1U0L A;  1XMD A;  1XMC A;  1GK3 A;  4A15 A;  4C5U A;  1K62 A;  2O7E A;  4BAA A;  4V2R A;  2NYN A;  3CRW 1;  2YV5 A;  1AUW A;  4IQJ M;  4MUM A;  4EEI A;  1Z4M A;  3UNV A;  3KDZ A;  1HY0 A;  1Q92 A;  1K7W A;  2O7D A;  1TJW A;  1YFM A;  1W27 A;  1Z4K A;  1Q5N A;  5H8W A;  5EYT A;  1T6P A;  1TJU A;  4FLC A;  1FUO A;  3RRP A;  2JAW A;  3R6Q A;  1XL7 A;  3R6V A;  4EFC A;  3QBP A;  1FUP A;  2RCN A;  3TV2 A;  4E88 A;  2J91 A;  4L6C A;  2PFM A;  4C5R A;  1U16 A;  1Z4P X;  4YIH A;  4V2Q A;  3F4R A;  1B8F A;  1VDK A;  2O7F A;  2O78 A;  2VSF A;  1IW7 D;  2D28 C;  1EB4 A;  4ADL A;  2HVG A;  1C3U A;  1MH9 A;  2PTR A;  4CQ5 A;  2VD6 A;  1Z4I A;  2VL7 A;  1TJ7 A;  1Z4Q A;  1DOF A;  2O6Y A;  3E04 A;  3CZO A;  3GZH A;  1XLY A;  4MWO A;  4YIK A;  1YIS A;  2FEN A;  2FUS A;  3NO9 A;  4NSL A;  2JAU A;  5HW2 A;  2JAO A;  1XL8 A;  1I0A A;  2NYF A;  2PTQ A;  3R6Y A;  2X75 A;  5D6B A;  1FUR A;  2QVE A;  3F4T A;  5M0I A;  1JSW A;  1U15 A;  5F91 A;  2RJR A;  1YFE A;  2O7B A;  3U19 A;  5F92 A;  1Z4L A;  2OHY A;  4FFX A;  1GK2 A;  1Q91 A;  1RE5 A;  4NFL A;  3C8T A;  4C5S A;  2JAR A; 
#chains in the Genus database with same CATH homology
 3OCF A;  2QGA B;  1Y2M A;  1DCN A;  4HGV A;  4APA A;  3KDY A;  4C6G A;  2RJS A;  1HY1 A;  1FUQ A;  4BAB A;  2E9F A;  3RD8 A;  2PTS A;  4MX2 A;  3NZ4 A;  1C3C A;  1GKJ A;  1KQ7 A;  4ADM A;  1T6J A;  1J3U A;  5EYV A;  4NLE A;  3OCE A;  1XWO A;  3BHG A;  4APB A;  2YII A;  1TJV A;  3GTD A;  1GKM A;  1GK3 A;  4C5U A;  1K62 A;  2O7E A;  4BAA A;  4V2R A;  2NYN A;  1AUW A;  4EEI A;  3UNV A;  3KDZ A;  1HY0 A;  2O7D A;  1K7W A;  1TJW A;  1YFM A;  1W27 A;  1Q5N A;  5EYT A;  1T6P A;  1TJU A;  4FLC A;  1FUO A;  3RRP A;  3R6Q A;  3R6V A;  4EFC A;  3QBP A;  1FUP A;  3TV2 A;  2J91 A;  2PFM A;  4C5R A;  1U16 A;  4V2Q A;  1B8F A;  1VDK A;  2O7F A;  2O78 A;  1EB4 A;  4ADL A;  2HVG A;  1C3U A;  2PTR A;  4CQ5 A;  2VD6 A;  1TJ7 A;  1DOF A;  2O6Y A;  3E04 A;  3CZO A;  3GZH A;  1YIS A;  2FUS A;  3NO9 A;  4NSL A;  5HW2 A;  2NYF A;  1I0A A;  2PTQ A;  3R6Y A;  2X75 A;  5D6B A;  1FUR A;  2QVE A;  1JSW A;  1U15 A;  5F91 A;  2RJR A;  1YFE A;  2O7B A;  5F92 A;  2OHY A;  4FFX A;  1GK2 A;  1RE5 A;  3C8T A;  4C5S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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