1C3CA

T. maritima adenylosuccinate lyase
Total Genus 171
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
171
sequence length
429
structure length
424
Chain Sequence
VERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords PROTEIN (ADENYLOSUCCINATE LYASE)
publication title The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
pubmed doi rcsb
source organism Thermotoga maritima
total genus 171
structure length 424
sequence length 429
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 1999-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1c3cA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1c3cA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1c3cA02
3GZHA 2YIIA 3E04A 2PTQA 1C3CA 4NLEA 2HVGA 1GKMA 3R6QA 2E9FA 4MX2A 2X75A 3OCEA 4V2QA 4BAAA 1J3UA 2FUSA 1GK3A 1YFEA 1HY0A 4C5SA 4CQ5A 1T6PA 1DCNA 5EYTA 1TJVA 4V2RA 1B8FA 2NYNA 1T6JA 4C5UA 1DOFA 1I0AA 3BHGA 3R6VA 3R6YA 3UNVA 1TJWA 2PFMA 5EYVA 1Q5NA 3GTDA 1FUPA 4APAA 3NO9A 3OCFA 1U16A 2O7DA 2O7FA 1AUWA 1FUOA 2O7BA 3KDZA 2PTSA 1GKJA 1EB4A 4C6GA 2RJSA 3RD8A 3KDYA 3TV2A 1TJ7A 1RE5A 1KQ7A 4FLCA 1XWOA 4ADLA 3RRPA 1FURA 4C5RA 1FUQA 1C3UA 4BABA 2QGAB 4FFXA 4HGVA 1K7WA 1YISA 1TJUA 1U15A 1Y2MA 4NSLA 1GK2A 3CZOA 3NZ4A 5HW2A 5D6BA 2O6YA 5F91A 4EFCA 1HY1A 1K62A 2O7EA 2VD6A 2RJRA 5F92A 2NYFA 3C8TA 4APBA 1VDKA 2J91A 2OHYA 1JSWA 2PTRA 4ADMA 4EEIA 3QBPA 2O78A 2QVEA 1W27A 1YFMA
chains in the Genus database with same CATH superfamily
3GZHA 2YIIA 3E04A 2YV5A 1MH9A 1Q92A 2PTQA 1C3CA 1T9HA 4NLEA 1Z4LA 2HVGA 1GKMA 1Z4PX 3R6QA 2E9FA 4MX2A 2VL7A 2D27A 2X75A 2JARA 1Z4IA 3OCEA 4V2QA 4BAAA 1J3UA 2FUSA 3CRW1 3F4RA 1GK3A 3CI0K 1YFEA 1HY0A 1XMDA 4C5SA 4CQ5A 1T6PA 4A15A 1DCNA 5EYTA 2JAWA 4L6CA 1TJVA 4V2RA 1B8FA 2NYNA 1T6JA 3U13A 4C5UA 1Q91A 1DOFA 1I0AA 3BHGA 3R6VA 3R6YA 3UNVA 1XL8A 1TJWA 2PFMA 5EYVA 1Q5NA 3GTDA 1Z4JA 1FUPA 4MWOA 4APAA 3NO9A 3OCFA 1U16A 1XMCA 1Z4MA 5M0JA 3CRVA 2O7DA 3BWVA 4YIHA 2O7FA 1AUWA 1FUOA 4YIKA 2O7BA 3KDZA 2PTSA 1GKJA 4IQJM 1EB4A 4C6GA 2RJSA 3F4SA 3RD8A 3KDYA 3TV2A 1Z4KA 2FENA 1TJ7A 1RE5A 2RCNA 1KQ7A 4FLCA 3F4TA 1XWOA 4ADLA 3RRPA 1FURA 4C5RA 1FUQA 1C3UA 4BABA 2QGAB 4FFXA 2I7DA 4HGVA 4L57A 1K7WA 1YISA 1TJUA 1U15A 1Y2MA 5H8WA 4NSLA 1GK2A 2JAOA 4E88A 2JAUA 1XLYA 4L6AA 3CZOA 4NFLA 1XL7A 3NZ4A 5HW2A 5D6BA 2O6YA 5F91A 1Z4QA 4EFCA 1HY1A 1K62A 2O7EA 2VD6A 2RJRA 4WNLA 2D28C 4MUMA 5F92A 2NYFA 1U0LA 5M0IA 1IW7D 3U19A 3C8TA 4APBA 1VDKA 2J91A 2FELA 2OHYA 2VSFA 1JSWA 2PTRA 4ADMA 4EEIA 3QBPA 2O78A 2QVEA 1W27A 1YFMA
chains in the Genus database with same CATH topology
3GZHA 2YIIA 3E04A 2PTQA 1C3CA 4NLEA 2HVGA 1GKMA 3R6QA 2E9FA 4MX2A 2X75A 3OCEA 4V2QA 4BAAA 1J3UA 2FUSA 1GK3A 1YFEA 1HY0A 4C5SA 4CQ5A 1T6PA 1DCNA 5EYTA 1TJVA 4V2RA 1B8FA 2NYNA 1T6JA 4C5UA 1DOFA 1I0AA 3BHGA 3R6VA 3R6YA 3UNVA 1TJWA 2PFMA 5EYVA 1Q5NA 3GTDA 1FUPA 4APAA 3NO9A 3OCFA 1U16A 2O7DA 2O7FA 1AUWA 1FUOA 2O7BA 3KDZA 2PTSA 1GKJA 1EB4A 4C6GA 2RJSA 3RD8A 3KDYA 3TV2A 1TJ7A 1RE5A 1KQ7A 4FLCA 1XWOA 4ADLA 3RRPA 1FURA 4C5RA 1FUQA 1C3UA 4BABA 2QGAB 4FFXA 4HGVA 1K7WA 1YISA 1TJUA 1U15A 1Y2MA 4NSLA 1GK2A 3CZOA 3NZ4A 5HW2A 5D6BA 2O6YA 5F91A 4EFCA 1HY1A 1K62A 2O7EA 2VD6A 2RJRA 5F92A 2NYFA 3C8TA 4APBA 1VDKA 2J91A 2OHYA 1JSWA 2PTRA 4ADMA 4EEIA 3QBPA 2O78A 2QVEA 1W27A 1YFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GZH A;  2YII A;  3E04 A;  2PTQ A;  1C3C A;  4NLE A;  2HVG A;  1GKM A;  3R6Q A;  2E9F A;  4MX2 A;  2X75 A;  3OCE A;  4V2Q A;  4BAA A;  1J3U A;  2FUS A;  1GK3 A;  1YFE A;  1HY0 A;  4C5S A;  4CQ5 A;  1T6P A;  1DCN A;  5EYT A;  1TJV A;  4V2R A;  1B8F A;  2NYN A;  1T6J A;  4C5U A;  1DOF A;  1I0A A;  3BHG A;  3R6V A;  3R6Y A;  3UNV A;  1TJW A;  2PFM A;  5EYV A;  1Q5N A;  3GTD A;  1FUP A;  4APA A;  3NO9 A;  3OCF A;  1U16 A;  2O7D A;  2O7F A;  1AUW A;  1FUO A;  2O7B A;  3KDZ A;  2PTS A;  1GKJ A;  1EB4 A;  4C6G A;  2RJS A;  3RD8 A;  3KDY A;  3TV2 A;  1TJ7 A;  1RE5 A;  1KQ7 A;  4FLC A;  1XWO A;  4ADL A;  3RRP A;  1FUR A;  4C5R A;  1FUQ A;  1C3U A;  4BAB A;  2QGA B;  4FFX A;  4HGV A;  1K7W A;  1YIS A;  1TJU A;  1U15 A;  1Y2M A;  4NSL A;  1GK2 A;  3CZO A;  3NZ4 A;  5HW2 A;  5D6B A;  2O6Y A;  5F91 A;  4EFC A;  1HY1 A;  1K62 A;  2O7E A;  2VD6 A;  2RJR A;  5F92 A;  2NYF A;  3C8T A;  4APB A;  1VDK A;  2J91 A;  2OHY A;  1JSW A;  2PTR A;  4ADM A;  4EEI A;  3QBP A;  2O78 A;  2QVE A;  1W27 A;  1YFM A; 
#chains in the Genus database with same CATH topology
 3GZH A;  2YII A;  3E04 A;  2YV5 A;  1MH9 A;  1Q92 A;  2PTQ A;  1C3C A;  1T9H A;  4NLE A;  1Z4L A;  2HVG A;  1GKM A;  1Z4P X;  3R6Q A;  2E9F A;  4MX2 A;  2VL7 A;  2D27 A;  2X75 A;  2JAR A;  1Z4I A;  3OCE A;  4V2Q A;  4BAA A;  1J3U A;  2FUS A;  3CRW 1;  3F4R A;  1GK3 A;  3CI0 K;  1YFE A;  1HY0 A;  1XMD A;  4C5S A;  4CQ5 A;  1T6P A;  4A15 A;  1DCN A;  5EYT A;  2JAW A;  4L6C A;  1TJV A;  4V2R A;  1B8F A;  2NYN A;  1T6J A;  3U13 A;  4C5U A;  1Q91 A;  1DOF A;  1I0A A;  3BHG A;  3R6V A;  3R6Y A;  3UNV A;  1XL8 A;  1TJW A;  2PFM A;  5EYV A;  1Q5N A;  3GTD A;  1Z4J A;  1FUP A;  4MWO A;  4APA A;  3NO9 A;  3OCF A;  1U16 A;  1XMC A;  1Z4M A;  5M0J A;  3CRV A;  2O7D A;  3BWV A;  4YIH A;  2O7F A;  1AUW A;  1FUO A;  4YIK A;  2O7B A;  3KDZ A;  2PTS A;  1GKJ A;  4IQJ M;  1EB4 A;  4C6G A;  2RJS A;  3F4S A;  3RD8 A;  3KDY A;  3TV2 A;  1Z4K A;  2FEN A;  1TJ7 A;  1RE5 A;  2RCN A;  1KQ7 A;  4FLC A;  3F4T A;  1XWO A;  4ADL A;  3RRP A;  1FUR A;  4C5R A;  1FUQ A;  1C3U A;  4BAB A;  2QGA B;  4FFX A;  2I7D A;  4HGV A;  4L57 A;  1K7W A;  1YIS A;  1TJU A;  1U15 A;  1Y2M A;  5H8W A;  4NSL A;  1GK2 A;  2JAO A;  4E88 A;  2JAU A;  1XLY A;  4L6A A;  3CZO A;  4NFL A;  1XL7 A;  3NZ4 A;  5HW2 A;  5D6B A;  2O6Y A;  5F91 A;  1Z4Q A;  4EFC A;  1HY1 A;  1K62 A;  2O7E A;  2VD6 A;  2RJR A;  4WNL A;  2D28 C;  4MUM A;  5F92 A;  2NYF A;  1U0L A;  5M0I A;  1IW7 D;  3U19 A;  3C8T A;  4APB A;  1VDK A;  2J91 A;  2FEL A;  2OHY A;  2VSF A;  1JSW A;  2PTR A;  4ADM A;  4EEI A;  3QBP A;  2O78 A;  2QVE A;  1W27 A;  1YFM A; 
#chains in the Genus database with same CATH homology
 3GZH A;  2YII A;  3E04 A;  2PTQ A;  1C3C A;  4NLE A;  2HVG A;  1GKM A;  3R6Q A;  2E9F A;  4MX2 A;  2X75 A;  3OCE A;  4V2Q A;  4BAA A;  1J3U A;  2FUS A;  1GK3 A;  1YFE A;  1HY0 A;  4C5S A;  4CQ5 A;  1T6P A;  1DCN A;  5EYT A;  1TJV A;  4V2R A;  1B8F A;  2NYN A;  1T6J A;  4C5U A;  1DOF A;  1I0A A;  3BHG A;  3R6V A;  3R6Y A;  3UNV A;  1TJW A;  2PFM A;  5EYV A;  1Q5N A;  3GTD A;  1FUP A;  4APA A;  3NO9 A;  3OCF A;  1U16 A;  2O7D A;  2O7F A;  1AUW A;  1FUO A;  2O7B A;  3KDZ A;  2PTS A;  1GKJ A;  1EB4 A;  4C6G A;  2RJS A;  3RD8 A;  3KDY A;  3TV2 A;  1TJ7 A;  1RE5 A;  1KQ7 A;  4FLC A;  1XWO A;  4ADL A;  3RRP A;  1FUR A;  4C5R A;  1FUQ A;  1C3U A;  4BAB A;  2QGA B;  4FFX A;  4HGV A;  1K7W A;  1YIS A;  1TJU A;  1U15 A;  1Y2M A;  4NSL A;  1GK2 A;  3CZO A;  3NZ4 A;  5HW2 A;  5D6B A;  2O6Y A;  5F91 A;  4EFC A;  1HY1 A;  1K62 A;  2O7E A;  2VD6 A;  2RJR A;  5F92 A;  2NYF A;  3C8T A;  4APB A;  1VDK A;  2J91 A;  2OHY A;  1JSW A;  2PTR A;  4ADM A;  4EEI A;  3QBP A;  2O78 A;  2QVE A;  1W27 A;  1YFM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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