1C3CA

T. maritima adenylosuccinate lyase
Total Genus 171
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
171
sequence length
429
structure length
424
Chain Sequence
VERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PROTEIN (ADENYLOSUCCINATE LYASE)
publication title The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase
total genus 171
structure length 424
sequence length 429
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 1999-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1c3cA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1c3cA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1c3cA02
4ADLA 3CZOA 4HGVA 4C5RA 2QGAB 1TJUA 2PTRA 3GTDA 2O7DA 3E04A 2O7EA 3UNVA 2E9FA 1EB4A 2YIIA 3NO9A 4MX2A 2RJSA 1YFMA 1GKMA 4NSLA 2PFMA 1YFEA 5F92A 2J91A 1FUPA 3C8TA 4C5UA 1J3UA 1K62A 4V2QA 1FUQA 2PTQA 3KDZA 3RRPA 3R6VA 2O7FA 1I0AA 4NLEA 1KQ7A 3TV2A 1TJVA 4EEIA 1W27A 2FUSA 3GZHA 4BAAA 1RE5A 1C3CA 2O78A 2QVEA 1VDKA 2OHYA 1T6JA 1Q5NA 1C3UA 4ADMA 1XWOA 4APBA 5D6BA 1HY1A 5EYVA 1YISA 1HY0A 1GK2A 2VD6A 3R6QA 3RD8A 1K7WA 3OCFA 5HW2A 2PTSA 5EYTA 3BHGA 1B8FA 1DCNA 1Y2MA 1AUWA 1FURA 4EFCA 1TJ7A 1U15A 4APAA 1GK3A 1U16A 1T6PA 5F91A 4V2RA 4CQ5A 3OCEA 2O7BA 2NYNA 2HVGA 1DOFA 4C5SA 4FLCA 4C6GA 3QBPA 2X75A 1FUOA 2RJRA 3R6YA 2NYFA 3NZ4A 1GKJA 1JSWA 2O6YA 3KDYA 1TJWA 4BABA 4FFXA
chains in the Genus database with same CATH superfamily
4ADLA 1U0LA 3CZOA 4HGVA 2D27A 2D28C 4C5RA 2QGAB 1TJUA 1Q91A 2PTRA 3GTDA 2O7DA 4A15A 3E04A 2O7EA 1Z4JA 3UNVA 2E9FA 1EB4A 2YIIA 3NO9A 4MX2A 2RJSA 1YFMA 1GKMA 4NSLA 2PFMA 1YFEA 5F92A 4MWOA 1Z4PX 2J91A 1FUPA 3C8TA 4C5UA 1J3UA 1K62A 4V2QA 1FUQA 2PTQA 3CRVA 3F4SA 3KDZA 3RRPA 3R6VA 2O7FA 1I0AA 2JAOA 4NFLA 4NLEA 1KQ7A 2JAUA 4L6CA 3TV2A 1TJVA 4EEIA 1W27A 2FUSA 4YIKA 3GZHA 2VL7A 4BAAA 1RE5A 1C3CA 4YIHA 2YV5A 3BWVA 4IQJM 5M0IA 3U13A 2JAWA 3F4TA 1XMDA 2O78A 1XMCA 2QVEA 1VDKA 2OHYA 1T6JA 1Q5NA 1C3UA 4ADMA 1XWOA 4APBA 1Z4IA 3U19A 1HY1A 5D6BA 5EYVA 1YISA 1HY0A 1GK2A 2VD6A 3R6QA 3RD8A 1Z4QA 1K7WA 3OCFA 5HW2A 2PTSA 1Z4KA 1Q92A 3CI0K 5EYTA 1XL7A 3BHGA 1B8FA 4MUMA 1DCNA 4E88A 3CRW1 1MH9A 1Y2MA 5H8WA 1T9HA 1AUWA 1FURA 4EFCA 1TJ7A 4L6AA 1U15A 4APAA 2JARA 1GK3A 1U16A 1Z4LA 1T6PA 5F91A 4V2RA 1Z4MA 4CQ5A 2VSFA 5M0JA 3OCEA 2O7BA 2NYNA 2HVGA 1IW7D 1XLYA 1DOFA 4C5SA 2FENA 3F4RA 4FLCA 4C6GA 3QBPA 2X75A 1XL8A 1FUOA 2RJRA 3R6YA 2NYFA 3NZ4A 1GKJA 1JSWA 2O6YA 3KDYA 2I7DA 2RCNA 1TJWA 4L57A 2FELA 4WNLA 4BABA 4FFXA
chains in the Genus database with same CATH topology
4ADLA 3CZOA 4HGVA 4C5RA 2QGAB 1TJUA 2PTRA 3GTDA 2O7DA 3E04A 2O7EA 3UNVA 2E9FA 1EB4A 2YIIA 3NO9A 4MX2A 2RJSA 1YFMA 1GKMA 4NSLA 2PFMA 1YFEA 5F92A 2J91A 1FUPA 3C8TA 4C5UA 1J3UA 1K62A 4V2QA 1FUQA 2PTQA 3KDZA 3RRPA 3R6VA 2O7FA 1I0AA 4NLEA 1KQ7A 3TV2A 1TJVA 4EEIA 1W27A 2FUSA 3GZHA 4BAAA 1RE5A 1C3CA 2O78A 2QVEA 1VDKA 2OHYA 1T6JA 1Q5NA 1C3UA 4ADMA 1XWOA 4APBA 5D6BA 1HY1A 5EYVA 1YISA 1HY0A 1GK2A 2VD6A 3R6QA 3RD8A 1K7WA 3OCFA 5HW2A 2PTSA 5EYTA 3BHGA 1B8FA 1DCNA 1Y2MA 1AUWA 1FURA 4EFCA 1TJ7A 1U15A 4APAA 1GK3A 1U16A 1T6PA 5F91A 4V2RA 4CQ5A 3OCEA 2O7BA 2NYNA 2HVGA 1DOFA 4C5SA 4FLCA 4C6GA 3QBPA 2X75A 1FUOA 2RJRA 3R6YA 2NYFA 3NZ4A 1GKJA 1JSWA 2O6YA 3KDYA 1TJWA 4BABA 4FFXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ADL A;  3CZO A;  4HGV A;  4C5R A;  2QGA B;  1TJU A;  2PTR A;  3GTD A;  2O7D A;  3E04 A;  2O7E A;  3UNV A;  2E9F A;  1EB4 A;  2YII A;  3NO9 A;  4MX2 A;  2RJS A;  1YFM A;  1GKM A;  4NSL A;  2PFM A;  1YFE A;  5F92 A;  2J91 A;  1FUP A;  3C8T A;  4C5U A;  1J3U A;  1K62 A;  4V2Q A;  1FUQ A;  2PTQ A;  3KDZ A;  3RRP A;  3R6V A;  2O7F A;  1I0A A;  4NLE A;  1KQ7 A;  3TV2 A;  1TJV A;  4EEI A;  1W27 A;  2FUS A;  3GZH A;  4BAA A;  1RE5 A;  1C3C A;  2O78 A;  2QVE A;  1VDK A;  2OHY A;  1T6J A;  1Q5N A;  1C3U A;  4ADM A;  1XWO A;  4APB A;  5D6B A;  1HY1 A;  5EYV A;  1YIS A;  1HY0 A;  1GK2 A;  2VD6 A;  3R6Q A;  3RD8 A;  1K7W A;  3OCF A;  5HW2 A;  2PTS A;  5EYT A;  3BHG A;  1B8F A;  1DCN A;  1Y2M A;  1AUW A;  1FUR A;  4EFC A;  1TJ7 A;  1U15 A;  4APA A;  1GK3 A;  1U16 A;  1T6P A;  5F91 A;  4V2R A;  4CQ5 A;  3OCE A;  2O7B A;  2NYN A;  2HVG A;  1DOF A;  4C5S A;  4FLC A;  4C6G A;  3QBP A;  2X75 A;  1FUO A;  2RJR A;  3R6Y A;  2NYF A;  3NZ4 A;  1GKJ A;  1JSW A;  2O6Y A;  3KDY A;  1TJW A;  4BAB A;  4FFX A; 
#chains in the Genus database with same CATH topology
 4ADL A;  1U0L A;  3CZO A;  4HGV A;  2D27 A;  2D28 C;  4C5R A;  2QGA B;  1TJU A;  1Q91 A;  2PTR A;  3GTD A;  2O7D A;  4A15 A;  3E04 A;  2O7E A;  1Z4J A;  3UNV A;  2E9F A;  1EB4 A;  2YII A;  3NO9 A;  4MX2 A;  2RJS A;  1YFM A;  1GKM A;  4NSL A;  2PFM A;  1YFE A;  5F92 A;  4MWO A;  1Z4P X;  2J91 A;  1FUP A;  3C8T A;  4C5U A;  1J3U A;  1K62 A;  4V2Q A;  1FUQ A;  2PTQ A;  3CRV A;  3F4S A;  3KDZ A;  3RRP A;  3R6V A;  2O7F A;  1I0A A;  2JAO A;  4NFL A;  4NLE A;  1KQ7 A;  2JAU A;  4L6C A;  3TV2 A;  1TJV A;  4EEI A;  1W27 A;  2FUS A;  4YIK A;  3GZH A;  2VL7 A;  4BAA A;  1RE5 A;  1C3C A;  4YIH A;  2YV5 A;  3BWV A;  4IQJ M;  5M0I A;  3U13 A;  2JAW A;  3F4T A;  1XMD A;  2O78 A;  1XMC A;  2QVE A;  1VDK A;  2OHY A;  1T6J A;  1Q5N A;  1C3U A;  4ADM A;  1XWO A;  4APB A;  1Z4I A;  3U19 A;  1HY1 A;  5D6B A;  5EYV A;  1YIS A;  1HY0 A;  1GK2 A;  2VD6 A;  3R6Q A;  3RD8 A;  1Z4Q A;  1K7W A;  3OCF A;  5HW2 A;  2PTS A;  1Z4K A;  1Q92 A;  3CI0 K;  5EYT A;  1XL7 A;  3BHG A;  1B8F A;  4MUM A;  1DCN A;  4E88 A;  3CRW 1;  1MH9 A;  1Y2M A;  5H8W A;  1T9H A;  1AUW A;  1FUR A;  4EFC A;  1TJ7 A;  4L6A A;  1U15 A;  4APA A;  2JAR A;  1GK3 A;  1U16 A;  1Z4L A;  1T6P A;  5F91 A;  4V2R A;  1Z4M A;  4CQ5 A;  2VSF A;  5M0J A;  3OCE A;  2O7B A;  2NYN A;  2HVG A;  1IW7 D;  1XLY A;  1DOF A;  4C5S A;  2FEN A;  3F4R A;  4FLC A;  4C6G A;  3QBP A;  2X75 A;  1XL8 A;  1FUO A;  2RJR A;  3R6Y A;  2NYF A;  3NZ4 A;  1GKJ A;  1JSW A;  2O6Y A;  3KDY A;  2I7D A;  2RCN A;  1TJW A;  4L57 A;  2FEL A;  4WNL A;  4BAB A;  4FFX A; 
#chains in the Genus database with same CATH homology
 4ADL A;  3CZO A;  4HGV A;  4C5R A;  2QGA B;  1TJU A;  2PTR A;  3GTD A;  2O7D A;  3E04 A;  2O7E A;  3UNV A;  2E9F A;  1EB4 A;  2YII A;  3NO9 A;  4MX2 A;  2RJS A;  1YFM A;  1GKM A;  4NSL A;  2PFM A;  1YFE A;  5F92 A;  2J91 A;  1FUP A;  3C8T A;  4C5U A;  1J3U A;  1K62 A;  4V2Q A;  1FUQ A;  2PTQ A;  3KDZ A;  3RRP A;  3R6V A;  2O7F A;  1I0A A;  4NLE A;  1KQ7 A;  3TV2 A;  1TJV A;  4EEI A;  1W27 A;  2FUS A;  3GZH A;  4BAA A;  1RE5 A;  1C3C A;  2O78 A;  2QVE A;  1VDK A;  2OHY A;  1T6J A;  1Q5N A;  1C3U A;  4ADM A;  1XWO A;  4APB A;  5D6B A;  1HY1 A;  5EYV A;  1YIS A;  1HY0 A;  1GK2 A;  2VD6 A;  3R6Q A;  3RD8 A;  1K7W A;  3OCF A;  5HW2 A;  2PTS A;  5EYT A;  3BHG A;  1B8F A;  1DCN A;  1Y2M A;  1AUW A;  1FUR A;  4EFC A;  1TJ7 A;  1U15 A;  4APA A;  1GK3 A;  1U16 A;  1T6P A;  5F91 A;  4V2R A;  4CQ5 A;  3OCE A;  2O7B A;  2NYN A;  2HVG A;  1DOF A;  4C5S A;  4FLC A;  4C6G A;  3QBP A;  2X75 A;  1FUO A;  2RJR A;  3R6Y A;  2NYF A;  3NZ4 A;  1GKJ A;  1JSW A;  2O6Y A;  3KDY A;  1TJW A;  4BAB A;  4FFX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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