1C3CA

T. maritima adenylosuccinate lyase
Total Genus 171
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
171
sequence length
429
structure length
424
Chain Sequence
VERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase
molecule keywords PROTEIN (ADENYLOSUCCINATE LYASE)
total genus 171
structure length 424
sequence length 429
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 1999-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1c3cA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1c3cA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1c3cA02
4BABA 2PFMA 1FUQA 1GKMA 4C5SA 1T6PA 1U16A 3QBPA 1GK2A 4FLCA 2O78A 3OCFA 1B8FA 4FFXA 5F91A 2O6YA 3GTDA 3CZOA 1K7WA 4ADLA 1TJVA 4V2RA 1Y2MA 5EYVA 2VD6A 1YISA 3KDZA 4C5RA 2RJRA 4CQ5A 1C3UA 4HGVA 4APAA 1YFEA 1HY1A 1K62A 1FURA 1GK3A 1W27A 2NYNA 2J91A 1GKJA 5EYTA 1XWOA 2HVGA 1J3UA 3E04A 4C5UA 2O7FA 5F92A 4MX2A 1FUPA 4EFCA 2RJSA 5D6BA 3R6YA 4ADMA 3TV2A 2PTRA 1T6JA 2O7DA 3KDYA 2O7BA 2QGAB 2E9FA 3R6VA 1HY0A 3UNVA 2QVEA 2FUSA 1I0AA 1TJUA 3GZHA 1DCNA 3OCEA 1YFMA 5HW2A 1VDKA 1C3CA 1FUOA 1U15A 1JSWA 2PTQA 2X75A 3C8TA 1EB4A 4EEIA 3RD8A 1TJ7A 1TJWA 2PTSA 1KQ7A 3BHGA 4NLEA 2OHYA 3NO9A 3RRPA 4APBA 4V2QA 2YIIA 3NZ4A 4NSLA 3R6QA 1RE5A 4C6GA 2NYFA 2O7EA 1Q5NA 1DOFA 1AUWA 4BAAA
chains in the Genus database with same CATH superfamily
4BABA 2PFMA 1Z4JA 1FUQA 1GKMA 4C5SA 2JAWA 1T6PA 4L6AA 1U16A 1Q91A 2FENA 3QBPA 4YIHA 1GK2A 2O78A 4FLCA 2JAOA 3OCFA 1B8FA 4FFXA 5F91A 2VSFA 2YV5A 2O6YA 3GTDA 3CZOA 1XMCA 1K7WA 1Z4PX 4IQJM 4NFLA 4ADLA 5M0JA 1TJVA 4V2RA 1XLYA 1Y2MA 5EYVA 2VL7A 1T9HA 3F4SA 3F4TA 2VD6A 3U19A 1YISA 3KDZA 4C5RA 2RJRA 4CQ5A 1XL7A 1C3UA 4HGVA 1Z4MA 4APAA 1YFEA 1HY1A 1K62A 1FURA 1GK3A 1W27A 2NYNA 2J91A 1GKJA 5EYTA 1XWOA 2HVGA 1J3UA 3E04A 1Z4KA 1U0LA 4C5UA 3CRW1 1Z4QA 2O7FA 1IW7D 1Z4IA 3CRVA 5F92A 3F4RA 3BWVA 4MX2A 1FUPA 2JAUA 4EFCA 2RJSA 5D6BA 3R6YA 4ADMA 3U13A 3TV2A 2PTRA 4MUMA 4MWOA 1T6JA 2O7DA 5H8WA 3KDYA 2O7BA 2QGAB 2E9FA 3R6VA 1HY0A 4E88A 3UNVA 2QVEA 2FUSA 1I0AA 2D28C 1TJUA 2JARA 3GZHA 1DCNA 1Z4LA 3OCEA 2FELA 1YFMA 5HW2A 1VDKA 4A15A 1C3CA 1FUOA 1U15A 1JSWA 2PTQA 2X75A 1MH9A 2RCNA 1Q92A 3CI0K 3C8TA 1EB4A 4EEIA 3RD8A 2I7DA 1TJ7A 1TJWA 4L57A 1XMDA 2PTSA 1KQ7A 4WNLA 3BHGA 4NLEA 2D27A 2OHYA 3NO9A 3RRPA 4APBA 4V2QA 2YIIA 3NZ4A 4NSLA 3R6QA 1RE5A 4L6CA 2NYFA 4C6GA 4YIKA 2O7EA 1Q5NA 1XL8A 1DOFA 5M0IA 1AUWA 4BAAA
chains in the Genus database with same CATH topology
4BABA 2PFMA 1FUQA 1GKMA 4C5SA 1T6PA 1U16A 3QBPA 1GK2A 4FLCA 2O78A 3OCFA 1B8FA 4FFXA 5F91A 2O6YA 3GTDA 3CZOA 1K7WA 4ADLA 1TJVA 4V2RA 1Y2MA 5EYVA 2VD6A 1YISA 3KDZA 4C5RA 2RJRA 4CQ5A 1C3UA 4HGVA 4APAA 1YFEA 1HY1A 1K62A 1FURA 1GK3A 1W27A 2NYNA 2J91A 1GKJA 5EYTA 1XWOA 2HVGA 1J3UA 3E04A 4C5UA 2O7FA 5F92A 4MX2A 1FUPA 4EFCA 2RJSA 5D6BA 3R6YA 4ADMA 3TV2A 2PTRA 1T6JA 2O7DA 3KDYA 2O7BA 2QGAB 2E9FA 3R6VA 1HY0A 3UNVA 2QVEA 2FUSA 1I0AA 1TJUA 3GZHA 1DCNA 3OCEA 1YFMA 5HW2A 1VDKA 1C3CA 1FUOA 1U15A 1JSWA 2PTQA 2X75A 3C8TA 1EB4A 4EEIA 3RD8A 1TJ7A 1TJWA 2PTSA 1KQ7A 3BHGA 4NLEA 2OHYA 3NO9A 3RRPA 4APBA 4V2QA 2YIIA 3NZ4A 4NSLA 3R6QA 1RE5A 4C6GA 2NYFA 2O7EA 1Q5NA 1DOFA 1AUWA 4BAAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BAB A;  2PFM A;  1FUQ A;  1GKM A;  4C5S A;  1T6P A;  1U16 A;  3QBP A;  1GK2 A;  4FLC A;  2O78 A;  3OCF A;  1B8F A;  4FFX A;  5F91 A;  2O6Y A;  3GTD A;  3CZO A;  1K7W A;  4ADL A;  1TJV A;  4V2R A;  1Y2M A;  5EYV A;  2VD6 A;  1YIS A;  3KDZ A;  4C5R A;  2RJR A;  4CQ5 A;  1C3U A;  4HGV A;  4APA A;  1YFE A;  1HY1 A;  1K62 A;  1FUR A;  1GK3 A;  1W27 A;  2NYN A;  2J91 A;  1GKJ A;  5EYT A;  1XWO A;  2HVG A;  1J3U A;  3E04 A;  4C5U A;  2O7F A;  5F92 A;  4MX2 A;  1FUP A;  4EFC A;  2RJS A;  5D6B A;  3R6Y A;  4ADM A;  3TV2 A;  2PTR A;  1T6J A;  2O7D A;  3KDY A;  2O7B A;  2QGA B;  2E9F A;  3R6V A;  1HY0 A;  3UNV A;  2QVE A;  2FUS A;  1I0A A;  1TJU A;  3GZH A;  1DCN A;  3OCE A;  1YFM A;  5HW2 A;  1VDK A;  1C3C A;  1FUO A;  1U15 A;  1JSW A;  2PTQ A;  2X75 A;  3C8T A;  1EB4 A;  4EEI A;  3RD8 A;  1TJ7 A;  1TJW A;  2PTS A;  1KQ7 A;  3BHG A;  4NLE A;  2OHY A;  3NO9 A;  3RRP A;  4APB A;  4V2Q A;  2YII A;  3NZ4 A;  4NSL A;  3R6Q A;  1RE5 A;  4C6G A;  2NYF A;  2O7E A;  1Q5N A;  1DOF A;  1AUW A;  4BAA A; 
#chains in the Genus database with same CATH topology
 4BAB A;  2PFM A;  1Z4J A;  1FUQ A;  1GKM A;  4C5S A;  2JAW A;  1T6P A;  4L6A A;  1U16 A;  1Q91 A;  2FEN A;  3QBP A;  4YIH A;  1GK2 A;  2O78 A;  4FLC A;  2JAO A;  3OCF A;  1B8F A;  4FFX A;  5F91 A;  2VSF A;  2YV5 A;  2O6Y A;  3GTD A;  3CZO A;  1XMC A;  1K7W A;  1Z4P X;  4IQJ M;  4NFL A;  4ADL A;  5M0J A;  1TJV A;  4V2R A;  1XLY A;  1Y2M A;  5EYV A;  2VL7 A;  1T9H A;  3F4S A;  3F4T A;  2VD6 A;  3U19 A;  1YIS A;  3KDZ A;  4C5R A;  2RJR A;  4CQ5 A;  1XL7 A;  1C3U A;  4HGV A;  1Z4M A;  4APA A;  1YFE A;  1HY1 A;  1K62 A;  1FUR A;  1GK3 A;  1W27 A;  2NYN A;  2J91 A;  1GKJ A;  5EYT A;  1XWO A;  2HVG A;  1J3U A;  3E04 A;  1Z4K A;  1U0L A;  4C5U A;  3CRW 1;  1Z4Q A;  2O7F A;  1IW7 D;  1Z4I A;  3CRV A;  5F92 A;  3F4R A;  3BWV A;  4MX2 A;  1FUP A;  2JAU A;  4EFC A;  2RJS A;  5D6B A;  3R6Y A;  4ADM A;  3U13 A;  3TV2 A;  2PTR A;  4MUM A;  4MWO A;  1T6J A;  2O7D A;  5H8W A;  3KDY A;  2O7B A;  2QGA B;  2E9F A;  3R6V A;  1HY0 A;  4E88 A;  3UNV A;  2QVE A;  2FUS A;  1I0A A;  2D28 C;  1TJU A;  2JAR A;  3GZH A;  1DCN A;  1Z4L A;  3OCE A;  2FEL A;  1YFM A;  5HW2 A;  1VDK A;  4A15 A;  1C3C A;  1FUO A;  1U15 A;  1JSW A;  2PTQ A;  2X75 A;  1MH9 A;  2RCN A;  1Q92 A;  3CI0 K;  3C8T A;  1EB4 A;  4EEI A;  3RD8 A;  2I7D A;  1TJ7 A;  1TJW A;  4L57 A;  1XMD A;  2PTS A;  1KQ7 A;  4WNL A;  3BHG A;  4NLE A;  2D27 A;  2OHY A;  3NO9 A;  3RRP A;  4APB A;  4V2Q A;  2YII A;  3NZ4 A;  4NSL A;  3R6Q A;  1RE5 A;  4L6C A;  2NYF A;  4C6G A;  4YIK A;  2O7E A;  1Q5N A;  1XL8 A;  1DOF A;  5M0I A;  1AUW A;  4BAA A; 
#chains in the Genus database with same CATH homology
 4BAB A;  2PFM A;  1FUQ A;  1GKM A;  4C5S A;  1T6P A;  1U16 A;  3QBP A;  1GK2 A;  4FLC A;  2O78 A;  3OCF A;  1B8F A;  4FFX A;  5F91 A;  2O6Y A;  3GTD A;  3CZO A;  1K7W A;  4ADL A;  1TJV A;  4V2R A;  1Y2M A;  5EYV A;  2VD6 A;  1YIS A;  3KDZ A;  4C5R A;  2RJR A;  4CQ5 A;  1C3U A;  4HGV A;  4APA A;  1YFE A;  1HY1 A;  1K62 A;  1FUR A;  1GK3 A;  1W27 A;  2NYN A;  2J91 A;  1GKJ A;  5EYT A;  1XWO A;  2HVG A;  1J3U A;  3E04 A;  4C5U A;  2O7F A;  5F92 A;  4MX2 A;  1FUP A;  4EFC A;  2RJS A;  5D6B A;  3R6Y A;  4ADM A;  3TV2 A;  2PTR A;  1T6J A;  2O7D A;  3KDY A;  2O7B A;  2QGA B;  2E9F A;  3R6V A;  1HY0 A;  3UNV A;  2QVE A;  2FUS A;  1I0A A;  1TJU A;  3GZH A;  1DCN A;  3OCE A;  1YFM A;  5HW2 A;  1VDK A;  1C3C A;  1FUO A;  1U15 A;  1JSW A;  2PTQ A;  2X75 A;  3C8T A;  1EB4 A;  4EEI A;  3RD8 A;  1TJ7 A;  1TJW A;  2PTS A;  1KQ7 A;  3BHG A;  4NLE A;  2OHY A;  3NO9 A;  3RRP A;  4APB A;  4V2Q A;  2YII A;  3NZ4 A;  4NSL A;  3R6Q A;  1RE5 A;  4C6G A;  2NYF A;  2O7E A;  1Q5N A;  1DOF A;  1AUW A;  4BAA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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