1C3CA

T. maritima adenylosuccinate lyase
Total Genus 171
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
171
sequence length
429
structure length
424
Chain Sequence
VERYSLSPMKDLWTEEAKYRRWLEVELAVTRAYEELGMIPKGVTERIRNNAKIDVELFKKIEEKTNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISGAVGNYANVPPEVEEKALSYLGLKPEPVSTQVVPRDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEEPFRKSAMPHKKNPITCERLTGLSRMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSQRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKKLVTKEELEELFDISYYLKHVDHIFERFEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase
molecule keywords PROTEIN (ADENYLOSUCCINATE LYASE)
total genus 171
structure length 424
sequence length 429
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 1999-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1c3cA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1c3cA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1c3cA02
2O6YA 4C5RA 3CZOA 1FUOA 4BABA 2PTSA 3NO9A 4ADLA 2FUSA 3E04A 3R6QA 3OCEA 1FUPA 2PTQA 3RRPA 2RJRA 4C6GA 4MX2A 2NYNA 2O7FA 3C8TA 1U15A 1DCNA 5F91A 3R6VA 1T6JA 1Y2MA 2O7DA 1GK3A 1B8FA 4FLCA 5HW2A 1I0AA 1TJWA 4HGVA 1FUQA 2QGAB 1DOFA 2YIIA 4CQ5A 1J3UA 3NZ4A 1K7WA 3KDYA 1KQ7A 2HVGA 1VDKA 1GKJA 3RD8A 1C3UA 2X75A 1C3CA 1JSWA 1U16A 4C5UA 4NSLA 3UNVA 4FFXA 2QVEA 1HY1A 3GTDA 2J91A 1XWOA 1YFEA 1TJVA 3GZHA 1HY0A 1GK2A 1YFMA 2RJSA 1W27A 3QBPA 3R6YA 1YISA 4APAA 1AUWA 3BHGA 4C5SA 5D6BA 2O78A 2O7BA 4EEIA 1TJUA 4V2QA 4NLEA 1FURA 4APBA 2PFMA 3OCFA 2OHYA 2VD6A 1RE5A 5EYTA 4EFCA 1EB4A 2E9FA 1K62A 4V2RA 4BAAA 5F92A 2O7EA 1T6PA 1Q5NA 4ADMA 2PTRA 3KDZA 2NYFA 3TV2A 5EYVA 1GKMA 1TJ7A
chains in the Genus database with same CATH superfamily
1XL8A 2O6YA 5H8WA 4C5RA 2YV5A 1Z4IA 3CZOA 1FUOA 3CI0K 2PTSA 3NO9A 4ADLA 2FUSA 4BABA 3E04A 3CRVA 3R6QA 3OCEA 1FUPA 2PTQA 3RRPA 2VL7A 2RJRA 1Z4QA 4C6GA 4MX2A 2JARA 2NYNA 1XMDA 1MH9A 2JAWA 1T9HA 2O7FA 4NFLA 4L6CA 3C8TA 1U15A 1DCNA 5F91A 3R6VA 1T6JA 1Y2MA 2O7DA 1GK3A 1B8FA 4FLCA 1Q92A 4MWOA 5HW2A 2D28C 1I0AA 4A15A 1TJWA 4HGVA 1Q91A 1FUQA 1Z4JA 2QGAB 1DOFA 2YIIA 4IQJM 4WNLA 1XMCA 3F4SA 4CQ5A 1J3UA 3NZ4A 1K7WA 3KDYA 1KQ7A 2HVGA 4L57A 1VDKA 1GKJA 2JAUA 2I7DA 3RD8A 1C3UA 3F4RA 2X75A 1C3CA 1JSWA 1XLYA 1U16A 4C5UA 1Z4LA 4NSLA 3UNVA 4FFXA 2QVEA 1HY1A 3GTDA 1Z4KA 4MUMA 2J91A 3CRW1 1XWOA 1YFEA 4L6AA 4YIKA 1TJVA 3GZHA 1HY0A 1GK2A 1YFMA 3F4TA 2RJSA 1Z4PX 1W27A 3QBPA 3R6YA 1U0LA 1XL7A 1YISA 4APAA 1AUWA 3BHGA 4C5SA 5D6BA 2O78A 2O7BA 4EEIA 5M0IA 1TJUA 4V2QA 3U19A 4NLEA 2D27A 1FURA 4APBA 2PFMA 3OCFA 2OHYA 2VD6A 1RE5A 3U13A 5EYTA 4EFCA 1EB4A 2E9FA 4E88A 1K62A 4V2RA 4BAAA 5F92A 2O7EA 1T6PA 2FELA 1Q5NA 4ADMA 2PTRA 2FENA 2JAOA 4YIHA 3KDZA 2VSFA 2NYFA 1Z4MA 3TV2A 1IW7D 5EYVA 2RCNA 5M0JA 1GKMA 1TJ7A 3BWVA
chains in the Genus database with same CATH topology
2O6YA 4C5RA 3CZOA 1FUOA 4BABA 2PTSA 3NO9A 4ADLA 2FUSA 3E04A 3R6QA 3OCEA 1FUPA 2PTQA 3RRPA 2RJRA 4C6GA 4MX2A 2NYNA 2O7FA 3C8TA 1U15A 1DCNA 5F91A 3R6VA 1T6JA 1Y2MA 2O7DA 1GK3A 1B8FA 4FLCA 5HW2A 1I0AA 1TJWA 4HGVA 1FUQA 2QGAB 1DOFA 2YIIA 4CQ5A 1J3UA 3NZ4A 1K7WA 3KDYA 1KQ7A 2HVGA 1VDKA 1GKJA 3RD8A 1C3UA 2X75A 1C3CA 1JSWA 1U16A 4C5UA 4NSLA 3UNVA 4FFXA 2QVEA 1HY1A 3GTDA 2J91A 1XWOA 1YFEA 1TJVA 3GZHA 1HY0A 1GK2A 1YFMA 2RJSA 1W27A 3QBPA 3R6YA 1YISA 4APAA 1AUWA 3BHGA 4C5SA 5D6BA 2O78A 2O7BA 4EEIA 1TJUA 4V2QA 4NLEA 1FURA 4APBA 2PFMA 3OCFA 2OHYA 2VD6A 1RE5A 5EYTA 4EFCA 1EB4A 2E9FA 1K62A 4V2RA 4BAAA 5F92A 2O7EA 1T6PA 1Q5NA 4ADMA 2PTRA 3KDZA 2NYFA 3TV2A 5EYVA 1GKMA 1TJ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O6Y A;  4C5R A;  3CZO A;  1FUO A;  4BAB A;  2PTS A;  3NO9 A;  4ADL A;  2FUS A;  3E04 A;  3R6Q A;  3OCE A;  1FUP A;  2PTQ A;  3RRP A;  2RJR A;  4C6G A;  4MX2 A;  2NYN A;  2O7F A;  3C8T A;  1U15 A;  1DCN A;  5F91 A;  3R6V A;  1T6J A;  1Y2M A;  2O7D A;  1GK3 A;  1B8F A;  4FLC A;  5HW2 A;  1I0A A;  1TJW A;  4HGV A;  1FUQ A;  2QGA B;  1DOF A;  2YII A;  4CQ5 A;  1J3U A;  3NZ4 A;  1K7W A;  3KDY A;  1KQ7 A;  2HVG A;  1VDK A;  1GKJ A;  3RD8 A;  1C3U A;  2X75 A;  1C3C A;  1JSW A;  1U16 A;  4C5U A;  4NSL A;  3UNV A;  4FFX A;  2QVE A;  1HY1 A;  3GTD A;  2J91 A;  1XWO A;  1YFE A;  1TJV A;  3GZH A;  1HY0 A;  1GK2 A;  1YFM A;  2RJS A;  1W27 A;  3QBP A;  3R6Y A;  1YIS A;  4APA A;  1AUW A;  3BHG A;  4C5S A;  5D6B A;  2O78 A;  2O7B A;  4EEI A;  1TJU A;  4V2Q A;  4NLE A;  1FUR A;  4APB A;  2PFM A;  3OCF A;  2OHY A;  2VD6 A;  1RE5 A;  5EYT A;  4EFC A;  1EB4 A;  2E9F A;  1K62 A;  4V2R A;  4BAA A;  5F92 A;  2O7E A;  1T6P A;  1Q5N A;  4ADM A;  2PTR A;  3KDZ A;  2NYF A;  3TV2 A;  5EYV A;  1GKM A;  1TJ7 A; 
#chains in the Genus database with same CATH topology
 1XL8 A;  2O6Y A;  5H8W A;  4C5R A;  2YV5 A;  1Z4I A;  3CZO A;  1FUO A;  3CI0 K;  2PTS A;  3NO9 A;  4ADL A;  2FUS A;  4BAB A;  3E04 A;  3CRV A;  3R6Q A;  3OCE A;  1FUP A;  2PTQ A;  3RRP A;  2VL7 A;  2RJR A;  1Z4Q A;  4C6G A;  4MX2 A;  2JAR A;  2NYN A;  1XMD A;  1MH9 A;  2JAW A;  1T9H A;  2O7F A;  4NFL A;  4L6C A;  3C8T A;  1U15 A;  1DCN A;  5F91 A;  3R6V A;  1T6J A;  1Y2M A;  2O7D A;  1GK3 A;  1B8F A;  4FLC A;  1Q92 A;  4MWO A;  5HW2 A;  2D28 C;  1I0A A;  4A15 A;  1TJW A;  4HGV A;  1Q91 A;  1FUQ A;  1Z4J A;  2QGA B;  1DOF A;  2YII A;  4IQJ M;  4WNL A;  1XMC A;  3F4S A;  4CQ5 A;  1J3U A;  3NZ4 A;  1K7W A;  3KDY A;  1KQ7 A;  2HVG A;  4L57 A;  1VDK A;  1GKJ A;  2JAU A;  2I7D A;  3RD8 A;  1C3U A;  3F4R A;  2X75 A;  1C3C A;  1JSW A;  1XLY A;  1U16 A;  4C5U A;  1Z4L A;  4NSL A;  3UNV A;  4FFX A;  2QVE A;  1HY1 A;  3GTD A;  1Z4K A;  4MUM A;  2J91 A;  3CRW 1;  1XWO A;  1YFE A;  4L6A A;  4YIK A;  1TJV A;  3GZH A;  1HY0 A;  1GK2 A;  1YFM A;  3F4T A;  2RJS A;  1Z4P X;  1W27 A;  3QBP A;  3R6Y A;  1U0L A;  1XL7 A;  1YIS A;  4APA A;  1AUW A;  3BHG A;  4C5S A;  5D6B A;  2O78 A;  2O7B A;  4EEI A;  5M0I A;  1TJU A;  4V2Q A;  3U19 A;  4NLE A;  2D27 A;  1FUR A;  4APB A;  2PFM A;  3OCF A;  2OHY A;  2VD6 A;  1RE5 A;  3U13 A;  5EYT A;  4EFC A;  1EB4 A;  2E9F A;  4E88 A;  1K62 A;  4V2R A;  4BAA A;  5F92 A;  2O7E A;  1T6P A;  2FEL A;  1Q5N A;  4ADM A;  2PTR A;  2FEN A;  2JAO A;  4YIH A;  3KDZ A;  2VSF A;  2NYF A;  1Z4M A;  3TV2 A;  1IW7 D;  5EYV A;  2RCN A;  5M0J A;  1GKM A;  1TJ7 A;  3BWV A; 
#chains in the Genus database with same CATH homology
 2O6Y A;  4C5R A;  3CZO A;  1FUO A;  4BAB A;  2PTS A;  3NO9 A;  4ADL A;  2FUS A;  3E04 A;  3R6Q A;  3OCE A;  1FUP A;  2PTQ A;  3RRP A;  2RJR A;  4C6G A;  4MX2 A;  2NYN A;  2O7F A;  3C8T A;  1U15 A;  1DCN A;  5F91 A;  3R6V A;  1T6J A;  1Y2M A;  2O7D A;  1GK3 A;  1B8F A;  4FLC A;  5HW2 A;  1I0A A;  1TJW A;  4HGV A;  1FUQ A;  2QGA B;  1DOF A;  2YII A;  4CQ5 A;  1J3U A;  3NZ4 A;  1K7W A;  3KDY A;  1KQ7 A;  2HVG A;  1VDK A;  1GKJ A;  3RD8 A;  1C3U A;  2X75 A;  1C3C A;  1JSW A;  1U16 A;  4C5U A;  4NSL A;  3UNV A;  4FFX A;  2QVE A;  1HY1 A;  3GTD A;  2J91 A;  1XWO A;  1YFE A;  1TJV A;  3GZH A;  1HY0 A;  1GK2 A;  1YFM A;  2RJS A;  1W27 A;  3QBP A;  3R6Y A;  1YIS A;  4APA A;  1AUW A;  3BHG A;  4C5S A;  5D6B A;  2O78 A;  2O7B A;  4EEI A;  1TJU A;  4V2Q A;  4NLE A;  1FUR A;  4APB A;  2PFM A;  3OCF A;  2OHY A;  2VD6 A;  1RE5 A;  5EYT A;  4EFC A;  1EB4 A;  2E9F A;  1K62 A;  4V2R A;  4BAA A;  5F92 A;  2O7E A;  1T6P A;  1Q5N A;  4ADM A;  2PTR A;  3KDZ A;  2NYF A;  3TV2 A;  5EYV A;  1GKM A;  1TJ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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