2HVGA

Crystal structure of adenylosuccinate lyase from plasmodium vivax
Total Genus 162
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
162
sequence length
458
structure length
447
Chain Sequence
HLKNISPIDGRYKKACGELSAFFSEHALIKHRIIVEVRWLLFLNEEELFFEKVTDHSVEVLNQIATNITDSDIARVKAIEHDVKAVEYFVKEKLKNSKREDLLKIKEYVHYLCTSEDINNVAYATCLKACLNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPASSTTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKKHFNLTYSIYCTQIQDHDYICELCDGLARANGTLIDLCVDIWLYISNNLLKLKSSTMPHKVNPIDFENAEGNLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGSSLAYCLIAYKSVLKGLNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQFTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTGYADYLAKNVERLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
pubmed doi rcsb
source organism Plasmodium vivax
molecule tags Lyase
molecule keywords Adenylosuccinate lyase
total genus 162
structure length 447
sequence length 458
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF08328 ASL_C Adenylosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2hvgA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2hvgA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2hvgA02
2VD6A 1FUPA 4CQ5A 4NLEA 2PTQA 1JSWA 5D6BA 2YIIA 5EYVA 1TJWA 1FUQA 2PTRA 3RRPA 2RJSA 2RJRA 3NZ4A 5EYTA 1DOFA 1Y2MA 1GK2A 1GKMA 2NYNA 2NYFA 2O7EA 1T6JA 1VDKA 1KQ7A 1Q5NA 3RD8A 4C6GA 1YFEA 5HW2A 4ADLA 1J3UA 1U16A 4ADMA 3QBPA 3OCEA 4C5SA 3R6VA 4V2RA 1YFMA 2HVGA 4BABA 2OHYA 3R6YA 3C8TA 2PFMA 3KDZA 1B8FA 4NSLA 1XWOA 1EB4A 1GKJA 1TJVA 1DCNA 1FURA 3CZOA 1U15A 4C5UA 4APBA 1C3UA 2O7FA 3TV2A 1AUWA 4EFCA 3KDYA 4FLCA 1RE5A 1W27A 4BAAA 1HY0A 1GK3A 2X75A 2E9FA 1TJ7A 4EEIA 1T6PA 1C3CA 1I0AA 1HY1A 1K7WA 2O7BA 4FFXA 3GZHA 2PTSA 5F92A 4HGVA 1FUOA 4V2QA 3R6QA 1K62A 2FUSA 2QGAB 4C5RA 1YISA 4APAA 3E04A 2J91A 3GTDA 3UNVA 1TJUA 3BHGA 2QVEA 2O78A 5F91A 4MX2A 2O6YA 3NO9A 2O7DA 3OCFA
chains in the Genus database with same CATH superfamily
2I7DA 2VD6A 1FUPA 4CQ5A 4WNLA 4NLEA 2PTQA 1JSWA 5D6BA 2YIIA 5EYVA 1TJWA 1Z4PX 1FUQA 2PTRA 3RRPA 2RJSA 1Z4IA 2RJRA 2VSFA 3F4SA 5M0IA 3NZ4A 2JAWA 5EYTA 1DOFA 1Y2MA 1Z4MA 1GK2A 1GKMA 2NYNA 4YIKA 2NYFA 2O7EA 3CI0K 1VDKA 1KQ7A 1Q5NA 3RD8A 1T6JA 1Z4JA 1U0LA 4C6GA 1MH9A 1YFEA 5HW2A 1IW7D 2YV5A 4ADLA 1J3UA 3CRW1 1U16A 4ADMA 3QBPA 3OCEA 4C5SA 1Q91A 3R6VA 3U13A 4V2RA 4MUMA 1YFMA 2HVGA 2JAUA 4YIHA 4BABA 4MWOA 2OHYA 2FELA 3R6YA 3C8TA 2PFMA 3KDZA 1B8FA 4A15A 4NSLA 1XWOA 1EB4A 1GKJA 1TJVA 1XMDA 1DCNA 2D27A 1FURA 3CZOA 4L6AA 1U15A 4C5UA 2JARA 5H8WA 4APBA 3F4TA 1Q92A 1C3UA 5M0JA 1Z4KA 2D28C 2O7FA 3TV2A 2VL7A 1XMCA 2FENA 1AUWA 4EFCA 3KDYA 1T9HA 4FLCA 1RE5A 1Z4QA 1W27A 4BAAA 1HY0A 4L6CA 4NFLA 1GK3A 1XLYA 2X75A 3CRVA 2E9FA 3BWVA 1XL7A 1TJ7A 4EEIA 1T6PA 1C3CA 1I0AA 1HY1A 1K7WA 4L57A 2O7BA 4FFXA 3GZHA 2RCNA 2PTSA 5F92A 4HGVA 1FUOA 4V2QA 3R6QA 1K62A 2FUSA 2QGAB 1XL8A 2JAOA 4C5RA 1YISA 4APAA 3E04A 2J91A 3GTDA 1Z4LA 3UNVA 1TJUA 3BHGA 3F4RA 2QVEA 4IQJM 2O78A 5F91A 4MX2A 2O6YA 4E88A 3U19A 3NO9A 2O7DA 3OCFA
chains in the Genus database with same CATH topology
2VD6A 1FUPA 4CQ5A 4NLEA 2PTQA 1JSWA 5D6BA 2YIIA 5EYVA 1TJWA 1FUQA 2PTRA 3RRPA 2RJSA 2RJRA 3NZ4A 5EYTA 1DOFA 1Y2MA 1GK2A 1GKMA 2NYNA 2NYFA 2O7EA 1T6JA 1VDKA 1KQ7A 1Q5NA 3RD8A 4C6GA 1YFEA 5HW2A 4ADLA 1J3UA 1U16A 4ADMA 3QBPA 3OCEA 4C5SA 3R6VA 4V2RA 1YFMA 2HVGA 4BABA 2OHYA 3R6YA 3C8TA 2PFMA 3KDZA 1B8FA 4NSLA 1XWOA 1EB4A 1GKJA 1TJVA 1DCNA 1FURA 3CZOA 1U15A 4C5UA 4APBA 1C3UA 2O7FA 3TV2A 1AUWA 4EFCA 3KDYA 4FLCA 1RE5A 1W27A 4BAAA 1HY0A 1GK3A 2X75A 2E9FA 1TJ7A 4EEIA 1T6PA 1C3CA 1I0AA 1HY1A 1K7WA 2O7BA 4FFXA 3GZHA 2PTSA 5F92A 4HGVA 1FUOA 4V2QA 3R6QA 1K62A 2FUSA 2QGAB 4C5RA 1YISA 4APAA 3E04A 2J91A 3GTDA 3UNVA 1TJUA 3BHGA 2QVEA 2O78A 5F91A 4MX2A 2O6YA 3NO9A 2O7DA 3OCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VD6 A;  1FUP A;  4CQ5 A;  4NLE A;  2PTQ A;  1JSW A;  5D6B A;  2YII A;  5EYV A;  1TJW A;  1FUQ A;  2PTR A;  3RRP A;  2RJS A;  2RJR A;  3NZ4 A;  5EYT A;  1DOF A;  1Y2M A;  1GK2 A;  1GKM A;  2NYN A;  2NYF A;  2O7E A;  1T6J A;  1VDK A;  1KQ7 A;  1Q5N A;  3RD8 A;  4C6G A;  1YFE A;  5HW2 A;  4ADL A;  1J3U A;  1U16 A;  4ADM A;  3QBP A;  3OCE A;  4C5S A;  3R6V A;  4V2R A;  1YFM A;  2HVG A;  4BAB A;  2OHY A;  3R6Y A;  3C8T A;  2PFM A;  3KDZ A;  1B8F A;  4NSL A;  1XWO A;  1EB4 A;  1GKJ A;  1TJV A;  1DCN A;  1FUR A;  3CZO A;  1U15 A;  4C5U A;  4APB A;  1C3U A;  2O7F A;  3TV2 A;  1AUW A;  4EFC A;  3KDY A;  4FLC A;  1RE5 A;  1W27 A;  4BAA A;  1HY0 A;  1GK3 A;  2X75 A;  2E9F A;  1TJ7 A;  4EEI A;  1T6P A;  1C3C A;  1I0A A;  1HY1 A;  1K7W A;  2O7B A;  4FFX A;  3GZH A;  2PTS A;  5F92 A;  4HGV A;  1FUO A;  4V2Q A;  3R6Q A;  1K62 A;  2FUS A;  2QGA B;  4C5R A;  1YIS A;  4APA A;  3E04 A;  2J91 A;  3GTD A;  3UNV A;  1TJU A;  3BHG A;  2QVE A;  2O78 A;  5F91 A;  4MX2 A;  2O6Y A;  3NO9 A;  2O7D A;  3OCF A; 
#chains in the Genus database with same CATH topology
 2I7D A;  2VD6 A;  1FUP A;  4CQ5 A;  4WNL A;  4NLE A;  2PTQ A;  1JSW A;  5D6B A;  2YII A;  5EYV A;  1TJW A;  1Z4P X;  1FUQ A;  2PTR A;  3RRP A;  2RJS A;  1Z4I A;  2RJR A;  2VSF A;  3F4S A;  5M0I A;  3NZ4 A;  2JAW A;  5EYT A;  1DOF A;  1Y2M A;  1Z4M A;  1GK2 A;  1GKM A;  2NYN A;  4YIK A;  2NYF A;  2O7E A;  3CI0 K;  1VDK A;  1KQ7 A;  1Q5N A;  3RD8 A;  1T6J A;  1Z4J A;  1U0L A;  4C6G A;  1MH9 A;  1YFE A;  5HW2 A;  1IW7 D;  2YV5 A;  4ADL A;  1J3U A;  3CRW 1;  1U16 A;  4ADM A;  3QBP A;  3OCE A;  4C5S A;  1Q91 A;  3R6V A;  3U13 A;  4V2R A;  4MUM A;  1YFM A;  2HVG A;  2JAU A;  4YIH A;  4BAB A;  4MWO A;  2OHY A;  2FEL A;  3R6Y A;  3C8T A;  2PFM A;  3KDZ A;  1B8F A;  4A15 A;  4NSL A;  1XWO A;  1EB4 A;  1GKJ A;  1TJV A;  1XMD A;  1DCN A;  2D27 A;  1FUR A;  3CZO A;  4L6A A;  1U15 A;  4C5U A;  2JAR A;  5H8W A;  4APB A;  3F4T A;  1Q92 A;  1C3U A;  5M0J A;  1Z4K A;  2D28 C;  2O7F A;  3TV2 A;  2VL7 A;  1XMC A;  2FEN A;  1AUW A;  4EFC A;  3KDY A;  1T9H A;  4FLC A;  1RE5 A;  1Z4Q A;  1W27 A;  4BAA A;  1HY0 A;  4L6C A;  4NFL A;  1GK3 A;  1XLY A;  2X75 A;  3CRV A;  2E9F A;  3BWV A;  1XL7 A;  1TJ7 A;  4EEI A;  1T6P A;  1C3C A;  1I0A A;  1HY1 A;  1K7W A;  4L57 A;  2O7B A;  4FFX A;  3GZH A;  2RCN A;  2PTS A;  5F92 A;  4HGV A;  1FUO A;  4V2Q A;  3R6Q A;  1K62 A;  2FUS A;  2QGA B;  1XL8 A;  2JAO A;  4C5R A;  1YIS A;  4APA A;  3E04 A;  2J91 A;  3GTD A;  1Z4L A;  3UNV A;  1TJU A;  3BHG A;  3F4R A;  2QVE A;  4IQJ M;  2O78 A;  5F91 A;  4MX2 A;  2O6Y A;  4E88 A;  3U19 A;  3NO9 A;  2O7D A;  3OCF A; 
#chains in the Genus database with same CATH homology
 2VD6 A;  1FUP A;  4CQ5 A;  4NLE A;  2PTQ A;  1JSW A;  5D6B A;  2YII A;  5EYV A;  1TJW A;  1FUQ A;  2PTR A;  3RRP A;  2RJS A;  2RJR A;  3NZ4 A;  5EYT A;  1DOF A;  1Y2M A;  1GK2 A;  1GKM A;  2NYN A;  2NYF A;  2O7E A;  1T6J A;  1VDK A;  1KQ7 A;  1Q5N A;  3RD8 A;  4C6G A;  1YFE A;  5HW2 A;  4ADL A;  1J3U A;  1U16 A;  4ADM A;  3QBP A;  3OCE A;  4C5S A;  3R6V A;  4V2R A;  1YFM A;  2HVG A;  4BAB A;  2OHY A;  3R6Y A;  3C8T A;  2PFM A;  3KDZ A;  1B8F A;  4NSL A;  1XWO A;  1EB4 A;  1GKJ A;  1TJV A;  1DCN A;  1FUR A;  3CZO A;  1U15 A;  4C5U A;  4APB A;  1C3U A;  2O7F A;  3TV2 A;  1AUW A;  4EFC A;  3KDY A;  4FLC A;  1RE5 A;  1W27 A;  4BAA A;  1HY0 A;  1GK3 A;  2X75 A;  2E9F A;  1TJ7 A;  4EEI A;  1T6P A;  1C3C A;  1I0A A;  1HY1 A;  1K7W A;  2O7B A;  4FFX A;  3GZH A;  2PTS A;  5F92 A;  4HGV A;  1FUO A;  4V2Q A;  3R6Q A;  1K62 A;  2FUS A;  2QGA B;  4C5R A;  1YIS A;  4APA A;  3E04 A;  2J91 A;  3GTD A;  3UNV A;  1TJU A;  3BHG A;  2QVE A;  2O78 A;  5F91 A;  4MX2 A;  2O6Y A;  3NO9 A;  2O7D A;  3OCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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