2HVGA

Crystal structure of adenylosuccinate lyase from plasmodium vivax
Total Genus 162
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
162
sequence length
458
structure length
447
Chain Sequence
HLKNISPIDGRYKKACGELSAFFSEHALIKHRIIVEVRWLLFLNEEELFFEKVTDHSVEVLNQIATNITDSDIARVKAIEHDVKAVEYFVKEKLKNSKREDLLKIKEYVHYLCTSEDINNVAYATCLKACLNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPASSTTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKKHFNLTYSIYCTQIQDHDYICELCDGLARANGTLIDLCVDIWLYISNNLLKLKSSTMPHKVNPIDFENAEGNLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGSSLAYCLIAYKSVLKGLNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQFTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTGYADYLAKNVERLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
pubmed doi rcsb
source organism Plasmodium vivax
molecule tags Lyase
total genus 162
structure length 447
sequence length 458
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF08328 ASL_C Adenylosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2hvgA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2hvgA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2hvgA02
1Q5NA 4CQ5A 3BHGA 2PFMA 1TJ7A 1C3CA 2HVGA 1C3UA 3C8TA 4C5UA 1HY0A 1FURA 2RJRA 5HW2A 3E04A 1GKMA 1Y2MA 1JSWA 2OHYA 4NLEA 4C5RA 4C6GA 1FUQA 3KDZA 1B8FA 1K7WA 4FLCA 3RD8A 1YISA 1VDKA 2NYFA 3NO9A 2J91A 5D6BA 1KQ7A 4APBA 2PTSA 3NZ4A 3GTDA 1T6PA 1FUOA 1YFMA 2YIIA 2PTRA 5F92A 1DOFA 3QBPA 5EYVA 2O6YA 3R6QA 3OCFA 3GZHA 1DCNA 3OCEA 4EEIA 3TV2A 4BABA 1FUPA 2E9FA 3CZOA 2QVEA 1AUWA 5EYTA 1GK2A 4HGVA 4ADLA 1XWOA 3KDYA 1K62A 2QGAB 2O7FA 4FFXA 1U15A 2O7BA 1W27A 3RRPA 4APAA 4MX2A 2O7EA 1J3UA 2VD6A 2O78A 1EB4A 4BAAA 4V2RA 3R6YA 1TJVA 2NYNA 1RE5A 1GK3A 3R6VA 4EFCA 1TJWA 4V2QA 4ADMA 1T6JA 2O7DA 1YFEA 2X75A 5F91A 3UNVA 4C5SA 1I0AA 2RJSA 1U16A 1HY1A 1TJUA 2PTQA 1GKJA 4NSLA 2FUSA
chains in the Genus database with same CATH superfamily
1Q5NA 4CQ5A 3CRW1 3BHGA 2PFMA 1TJ7A 1C3CA 4L6CA 4YIHA 2HVGA 1C3UA 3C8TA 2RCNA 4C5UA 1HY0A 3CI0K 2FELA 1FURA 2JAWA 2RJRA 5HW2A 3E04A 3F4SA 1GKMA 1Y2MA 1JSWA 4L57A 2OHYA 4NLEA 4C5RA 1Q92A 4YIKA 2VL7A 4C6GA 1FUQA 5M0JA 3KDZA 1B8FA 1K7WA 1XL7A 4WNLA 4FLCA 3RD8A 1YISA 2D27A 3F4RA 4A15A 1VDKA 2NYFA 2JARA 3NO9A 1XMDA 2J91A 5D6BA 1KQ7A 4APBA 2PTSA 3NZ4A 3GTDA 1T6PA 1FUOA 2YV5A 1XL8A 1YFMA 2YIIA 1XMCA 4MUMA 2PTRA 5F92A 1DOFA 3QBPA 5EYVA 2O6YA 3R6QA 3OCFA 3GZHA 1DCNA 3OCEA 4EEIA 3F4TA 3TV2A 4BABA 1FUPA 2E9FA 3CZOA 2I7DA 2QVEA 1AUWA 1MH9A 5EYTA 4E88A 1GK2A 4HGVA 4ADLA 1XWOA 3KDYA 1Z4QA 1Z4PX 1K62A 2QGAB 2O7FA 4FFXA 1U15A 2O7BA 1XLYA 1Q91A 1W27A 3RRPA 4APAA 4MX2A 2O7EA 2VSFA 1J3UA 1Z4MA 1U0LA 2JAUA 2VD6A 1Z4KA 2O78A 1Z4IA 1EB4A 4BAAA 4V2RA 3R6YA 1TJVA 4IQJM 2NYNA 5M0IA 3BWVA 5H8WA 1RE5A 1GK3A 3R6VA 1Z4LA 4L6AA 4NFLA 4EFCA 2D28C 1TJWA 4V2QA 4ADMA 4MWOA 3U19A 1T6JA 2O7DA 1YFEA 1Z4JA 2X75A 5F91A 3UNVA 3CRVA 4C5SA 1I0AA 3U13A 2RJSA 1U16A 1HY1A 1TJUA 2PTQA 1GKJA 2FENA 1IW7D 2JAOA 4NSLA 2FUSA 1T9HA
chains in the Genus database with same CATH topology
1Q5NA 4CQ5A 3BHGA 2PFMA 1TJ7A 1C3CA 2HVGA 1C3UA 3C8TA 4C5UA 1HY0A 1FURA 2RJRA 5HW2A 3E04A 1GKMA 1Y2MA 1JSWA 2OHYA 4NLEA 4C5RA 4C6GA 1FUQA 3KDZA 1B8FA 1K7WA 4FLCA 3RD8A 1YISA 1VDKA 2NYFA 3NO9A 2J91A 5D6BA 1KQ7A 4APBA 2PTSA 3NZ4A 3GTDA 1T6PA 1FUOA 1YFMA 2YIIA 2PTRA 5F92A 1DOFA 3QBPA 5EYVA 2O6YA 3R6QA 3OCFA 3GZHA 1DCNA 3OCEA 4EEIA 3TV2A 4BABA 1FUPA 2E9FA 3CZOA 2QVEA 1AUWA 5EYTA 1GK2A 4HGVA 4ADLA 1XWOA 3KDYA 1K62A 2QGAB 2O7FA 4FFXA 1U15A 2O7BA 1W27A 3RRPA 4APAA 4MX2A 2O7EA 1J3UA 2VD6A 2O78A 1EB4A 4BAAA 4V2RA 3R6YA 1TJVA 2NYNA 1RE5A 1GK3A 3R6VA 4EFCA 1TJWA 4V2QA 4ADMA 1T6JA 2O7DA 1YFEA 2X75A 5F91A 3UNVA 4C5SA 1I0AA 2RJSA 1U16A 1HY1A 1TJUA 2PTQA 1GKJA 4NSLA 2FUSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q5N A;  4CQ5 A;  3BHG A;  2PFM A;  1TJ7 A;  1C3C A;  2HVG A;  1C3U A;  3C8T A;  4C5U A;  1HY0 A;  1FUR A;  2RJR A;  5HW2 A;  3E04 A;  1GKM A;  1Y2M A;  1JSW A;  2OHY A;  4NLE A;  4C5R A;  4C6G A;  1FUQ A;  3KDZ A;  1B8F A;  1K7W A;  4FLC A;  3RD8 A;  1YIS A;  1VDK A;  2NYF A;  3NO9 A;  2J91 A;  5D6B A;  1KQ7 A;  4APB A;  2PTS A;  3NZ4 A;  3GTD A;  1T6P A;  1FUO A;  1YFM A;  2YII A;  2PTR A;  5F92 A;  1DOF A;  3QBP A;  5EYV A;  2O6Y A;  3R6Q A;  3OCF A;  3GZH A;  1DCN A;  3OCE A;  4EEI A;  3TV2 A;  4BAB A;  1FUP A;  2E9F A;  3CZO A;  2QVE A;  1AUW A;  5EYT A;  1GK2 A;  4HGV A;  4ADL A;  1XWO A;  3KDY A;  1K62 A;  2QGA B;  2O7F A;  4FFX A;  1U15 A;  2O7B A;  1W27 A;  3RRP A;  4APA A;  4MX2 A;  2O7E A;  1J3U A;  2VD6 A;  2O78 A;  1EB4 A;  4BAA A;  4V2R A;  3R6Y A;  1TJV A;  2NYN A;  1RE5 A;  1GK3 A;  3R6V A;  4EFC A;  1TJW A;  4V2Q A;  4ADM A;  1T6J A;  2O7D A;  1YFE A;  2X75 A;  5F91 A;  3UNV A;  4C5S A;  1I0A A;  2RJS A;  1U16 A;  1HY1 A;  1TJU A;  2PTQ A;  1GKJ A;  4NSL A;  2FUS A; 
#chains in the Genus database with same CATH topology
 1Q5N A;  4CQ5 A;  3CRW 1;  3BHG A;  2PFM A;  1TJ7 A;  1C3C A;  4L6C A;  4YIH A;  2HVG A;  1C3U A;  3C8T A;  2RCN A;  4C5U A;  1HY0 A;  3CI0 K;  2FEL A;  1FUR A;  2JAW A;  2RJR A;  5HW2 A;  3E04 A;  3F4S A;  1GKM A;  1Y2M A;  1JSW A;  4L57 A;  2OHY A;  4NLE A;  4C5R A;  1Q92 A;  4YIK A;  2VL7 A;  4C6G A;  1FUQ A;  5M0J A;  3KDZ A;  1B8F A;  1K7W A;  1XL7 A;  4WNL A;  4FLC A;  3RD8 A;  1YIS A;  2D27 A;  3F4R A;  4A15 A;  1VDK A;  2NYF A;  2JAR A;  3NO9 A;  1XMD A;  2J91 A;  5D6B A;  1KQ7 A;  4APB A;  2PTS A;  3NZ4 A;  3GTD A;  1T6P A;  1FUO A;  2YV5 A;  1XL8 A;  1YFM A;  2YII A;  1XMC A;  4MUM A;  2PTR A;  5F92 A;  1DOF A;  3QBP A;  5EYV A;  2O6Y A;  3R6Q A;  3OCF A;  3GZH A;  1DCN A;  3OCE A;  4EEI A;  3F4T A;  3TV2 A;  4BAB A;  1FUP A;  2E9F A;  3CZO A;  2I7D A;  2QVE A;  1AUW A;  1MH9 A;  5EYT A;  4E88 A;  1GK2 A;  4HGV A;  4ADL A;  1XWO A;  3KDY A;  1Z4Q A;  1Z4P X;  1K62 A;  2QGA B;  2O7F A;  4FFX A;  1U15 A;  2O7B A;  1XLY A;  1Q91 A;  1W27 A;  3RRP A;  4APA A;  4MX2 A;  2O7E A;  2VSF A;  1J3U A;  1Z4M A;  1U0L A;  2JAU A;  2VD6 A;  1Z4K A;  2O78 A;  1Z4I A;  1EB4 A;  4BAA A;  4V2R A;  3R6Y A;  1TJV A;  4IQJ M;  2NYN A;  5M0I A;  3BWV A;  5H8W A;  1RE5 A;  1GK3 A;  3R6V A;  1Z4L A;  4L6A A;  4NFL A;  4EFC A;  2D28 C;  1TJW A;  4V2Q A;  4ADM A;  4MWO A;  3U19 A;  1T6J A;  2O7D A;  1YFE A;  1Z4J A;  2X75 A;  5F91 A;  3UNV A;  3CRV A;  4C5S A;  1I0A A;  3U13 A;  2RJS A;  1U16 A;  1HY1 A;  1TJU A;  2PTQ A;  1GKJ A;  2FEN A;  1IW7 D;  2JAO A;  4NSL A;  2FUS A;  1T9H A; 
#chains in the Genus database with same CATH homology
 1Q5N A;  4CQ5 A;  3BHG A;  2PFM A;  1TJ7 A;  1C3C A;  2HVG A;  1C3U A;  3C8T A;  4C5U A;  1HY0 A;  1FUR A;  2RJR A;  5HW2 A;  3E04 A;  1GKM A;  1Y2M A;  1JSW A;  2OHY A;  4NLE A;  4C5R A;  4C6G A;  1FUQ A;  3KDZ A;  1B8F A;  1K7W A;  4FLC A;  3RD8 A;  1YIS A;  1VDK A;  2NYF A;  3NO9 A;  2J91 A;  5D6B A;  1KQ7 A;  4APB A;  2PTS A;  3NZ4 A;  3GTD A;  1T6P A;  1FUO A;  1YFM A;  2YII A;  2PTR A;  5F92 A;  1DOF A;  3QBP A;  5EYV A;  2O6Y A;  3R6Q A;  3OCF A;  3GZH A;  1DCN A;  3OCE A;  4EEI A;  3TV2 A;  4BAB A;  1FUP A;  2E9F A;  3CZO A;  2QVE A;  1AUW A;  5EYT A;  1GK2 A;  4HGV A;  4ADL A;  1XWO A;  3KDY A;  1K62 A;  2QGA B;  2O7F A;  4FFX A;  1U15 A;  2O7B A;  1W27 A;  3RRP A;  4APA A;  4MX2 A;  2O7E A;  1J3U A;  2VD6 A;  2O78 A;  1EB4 A;  4BAA A;  4V2R A;  3R6Y A;  1TJV A;  2NYN A;  1RE5 A;  1GK3 A;  3R6V A;  4EFC A;  1TJW A;  4V2Q A;  4ADM A;  1T6J A;  2O7D A;  1YFE A;  2X75 A;  5F91 A;  3UNV A;  4C5S A;  1I0A A;  2RJS A;  1U16 A;  1HY1 A;  1TJU A;  2PTQ A;  1GKJ A;  4NSL A;  2FUS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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