2HVGA

Crystal structure of adenylosuccinate lyase from plasmodium vivax
Total Genus 162
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
162
sequence length
458
structure length
447
Chain Sequence
HLKNISPIDGRYKKACGELSAFFSEHALIKHRIIVEVRWLLFLNEEELFFEKVTDHSVEVLNQIATNITDSDIARVKAIEHDVKAVEYFVKEKLKNSKREDLLKIKEYVHYLCTSEDINNVAYATCLKACLNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPASSTTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKKHFNLTYSIYCTQIQDHDYICELCDGLARANGTLIDLCVDIWLYISNNLLKLKSSTMPHKVNPIDFENAEGNLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGSSLAYCLIAYKSVLKGLNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQFTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTGYADYLAKNVERLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Adenylosuccinate lyase
publication title Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
pubmed doi rcsb
source organism Plasmodium vivax
total genus 162
structure length 447
sequence length 458
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2006-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF08328 ASL_C Adenylosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2hvgA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2hvgA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2hvgA02
4EEIA 1Q5NA 3R6VA 1T6PA 1JSWA 2QVEA 2HVGA 1FUOA 3BHGA 4ADLA 2PTRA 2VD6A 2O7DA 4APAA 4HGVA 1DCNA 1GKMA 1TJ7A 1TJUA 2O6YA 4APBA 1GKJA 3CZOA 3OCFA 4C5RA 4EFCA 3KDYA 5D6BA 2NYFA 3UNVA 1FUPA 2OHYA 4CQ5A 1I0AA 2YIIA 2O7BA 2O78A 1GK2A 4NSLA 4MX2A 2QGAB 1TJVA 1VDKA 2X75A 2O7FA 3RRPA 1K7WA 4FLCA 4C6GA 1HY1A 1AUWA 5F91A 2FUSA 5F92A 1FUQA 1EB4A 1HY0A 4NLEA 1U16A 1J3UA 5EYVA 1W27A 3KDZA 3RD8A 4ADMA 4FFXA 1C3UA 3E04A 5HW2A 1C3CA 2RJRA 4BABA 1KQ7A 2NYNA 2PFMA 1DOFA 3C8TA 2J91A 5EYTA 1Y2MA 1FURA 2E9FA 2PTQA 1T6JA 3R6YA 1TJWA 1YISA 2RJSA 1K62A 4V2RA 3GTDA 2O7EA 4C5UA 1U15A 3GZHA 3OCEA 3R6QA 4BAAA 2PTSA 4V2QA 1XWOA 3NZ4A 1GK3A 1YFEA 1RE5A 1YFMA 3NO9A 1B8FA 3QBPA 4C5SA 3TV2A
chains in the Genus database with same CATH superfamily
4EEIA 1Q5NA 3R6VA 1T6PA 1JSWA 4L57A 2QVEA 2HVGA 1FUOA 3BHGA 1Z4KA 2PTRA 4ADLA 2VD6A 2O7DA 4APAA 4HGVA 4E88A 1DCNA 1XL8A 1GKMA 1TJ7A 1TJUA 2O6YA 3F4RA 4APBA 3U19A 1GKJA 1Q92A 5H8WA 3CZOA 3OCFA 4C5RA 4EFCA 3BWVA 3KDYA 5D6BA 2NYFA 3UNVA 1XLYA 1FUPA 2OHYA 4CQ5A 1I0AA 2YIIA 4NFLA 2O7BA 2O78A 2VL7A 1GK2A 1Z4LA 4NSLA 4MX2A 2VSFA 4A15A 2QGAB 1IW7D 1TJVA 1VDKA 2X75A 2O7FA 2I7DA 2D27A 3RRPA 1K7WA 4FLCA 4C6GA 4WNLA 1HY1A 1U0LA 3U13A 4L6AA 1AUWA 5F91A 1Z4JA 2FUSA 5F92A 1FUQA 3CRVA 1EB4A 2FENA 1HY0A 4NLEA 1U16A 1J3UA 1XMCA 1Z4PX 5EYVA 4YIHA 1W27A 5M0IA 2FELA 4YIKA 3KDZA 1MH9A 2RCNA 3RD8A 4ADMA 1T9HA 1C3UA 4FFXA 3E04A 1Z4MA 5HW2A 1C3CA 3F4TA 1Z4QA 2RJRA 4BABA 1KQ7A 2NYNA 2PFMA 2JAUA 1DOFA 2JARA 3C8TA 2J91A 4IQJM 5EYTA 1Y2MA 1Q91A 1FURA 3F4SA 2JAOA 2E9FA 2PTQA 1T6JA 3R6YA 1TJWA 1YISA 2RJSA 1K62A 3CRW1 4V2RA 3GTDA 2O7EA 4C5UA 1XMDA 1U15A 3GZHA 3OCEA 3R6QA 4BAAA 2PTSA 1Z4IA 2YV5A 4V2QA 1XWOA 4MWOA 3NZ4A 2D28C 1GK3A 1YFEA 3CI0K 1XL7A 1RE5A 1YFMA 3NO9A 1B8FA 3QBPA 4C5SA 3TV2A 2JAWA 4MUMA 5M0JA 4L6CA
chains in the Genus database with same CATH topology
4EEIA 1Q5NA 3R6VA 1T6PA 1JSWA 2QVEA 2HVGA 1FUOA 3BHGA 4ADLA 2PTRA 2VD6A 2O7DA 4APAA 4HGVA 1DCNA 1GKMA 1TJ7A 1TJUA 2O6YA 4APBA 1GKJA 3CZOA 3OCFA 4C5RA 4EFCA 3KDYA 5D6BA 2NYFA 3UNVA 1FUPA 2OHYA 4CQ5A 1I0AA 2YIIA 2O7BA 2O78A 1GK2A 4NSLA 4MX2A 2QGAB 1TJVA 1VDKA 2X75A 2O7FA 3RRPA 1K7WA 4FLCA 4C6GA 1HY1A 1AUWA 5F91A 2FUSA 5F92A 1FUQA 1EB4A 1HY0A 4NLEA 1U16A 1J3UA 5EYVA 1W27A 3KDZA 3RD8A 4ADMA 4FFXA 1C3UA 3E04A 5HW2A 1C3CA 2RJRA 4BABA 1KQ7A 2NYNA 2PFMA 1DOFA 3C8TA 2J91A 5EYTA 1Y2MA 1FURA 2E9FA 2PTQA 1T6JA 3R6YA 1TJWA 1YISA 2RJSA 1K62A 4V2RA 3GTDA 2O7EA 4C5UA 1U15A 3GZHA 3OCEA 3R6QA 4BAAA 2PTSA 4V2QA 1XWOA 3NZ4A 1GK3A 1YFEA 1RE5A 1YFMA 3NO9A 1B8FA 3QBPA 4C5SA 3TV2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EEI A;  1Q5N A;  3R6V A;  1T6P A;  1JSW A;  2QVE A;  2HVG A;  1FUO A;  3BHG A;  4ADL A;  2PTR A;  2VD6 A;  2O7D A;  4APA A;  4HGV A;  1DCN A;  1GKM A;  1TJ7 A;  1TJU A;  2O6Y A;  4APB A;  1GKJ A;  3CZO A;  3OCF A;  4C5R A;  4EFC A;  3KDY A;  5D6B A;  2NYF A;  3UNV A;  1FUP A;  2OHY A;  4CQ5 A;  1I0A A;  2YII A;  2O7B A;  2O78 A;  1GK2 A;  4NSL A;  4MX2 A;  2QGA B;  1TJV A;  1VDK A;  2X75 A;  2O7F A;  3RRP A;  1K7W A;  4FLC A;  4C6G A;  1HY1 A;  1AUW A;  5F91 A;  2FUS A;  5F92 A;  1FUQ A;  1EB4 A;  1HY0 A;  4NLE A;  1U16 A;  1J3U A;  5EYV A;  1W27 A;  3KDZ A;  3RD8 A;  4ADM A;  4FFX A;  1C3U A;  3E04 A;  5HW2 A;  1C3C A;  2RJR A;  4BAB A;  1KQ7 A;  2NYN A;  2PFM A;  1DOF A;  3C8T A;  2J91 A;  5EYT A;  1Y2M A;  1FUR A;  2E9F A;  2PTQ A;  1T6J A;  3R6Y A;  1TJW A;  1YIS A;  2RJS A;  1K62 A;  4V2R A;  3GTD A;  2O7E A;  4C5U A;  1U15 A;  3GZH A;  3OCE A;  3R6Q A;  4BAA A;  2PTS A;  4V2Q A;  1XWO A;  3NZ4 A;  1GK3 A;  1YFE A;  1RE5 A;  1YFM A;  3NO9 A;  1B8F A;  3QBP A;  4C5S A;  3TV2 A; 
#chains in the Genus database with same CATH topology
 4EEI A;  1Q5N A;  3R6V A;  1T6P A;  1JSW A;  4L57 A;  2QVE A;  2HVG A;  1FUO A;  3BHG A;  1Z4K A;  2PTR A;  4ADL A;  2VD6 A;  2O7D A;  4APA A;  4HGV A;  4E88 A;  1DCN A;  1XL8 A;  1GKM A;  1TJ7 A;  1TJU A;  2O6Y A;  3F4R A;  4APB A;  3U19 A;  1GKJ A;  1Q92 A;  5H8W A;  3CZO A;  3OCF A;  4C5R A;  4EFC A;  3BWV A;  3KDY A;  5D6B A;  2NYF A;  3UNV A;  1XLY A;  1FUP A;  2OHY A;  4CQ5 A;  1I0A A;  2YII A;  4NFL A;  2O7B A;  2O78 A;  2VL7 A;  1GK2 A;  1Z4L A;  4NSL A;  4MX2 A;  2VSF A;  4A15 A;  2QGA B;  1IW7 D;  1TJV A;  1VDK A;  2X75 A;  2O7F A;  2I7D A;  2D27 A;  3RRP A;  1K7W A;  4FLC A;  4C6G A;  4WNL A;  1HY1 A;  1U0L A;  3U13 A;  4L6A A;  1AUW A;  5F91 A;  1Z4J A;  2FUS A;  5F92 A;  1FUQ A;  3CRV A;  1EB4 A;  2FEN A;  1HY0 A;  4NLE A;  1U16 A;  1J3U A;  1XMC A;  1Z4P X;  5EYV A;  4YIH A;  1W27 A;  5M0I A;  2FEL A;  4YIK A;  3KDZ A;  1MH9 A;  2RCN A;  3RD8 A;  4ADM A;  1T9H A;  1C3U A;  4FFX A;  3E04 A;  1Z4M A;  5HW2 A;  1C3C A;  3F4T A;  1Z4Q A;  2RJR A;  4BAB A;  1KQ7 A;  2NYN A;  2PFM A;  2JAU A;  1DOF A;  2JAR A;  3C8T A;  2J91 A;  4IQJ M;  5EYT A;  1Y2M A;  1Q91 A;  1FUR A;  3F4S A;  2JAO A;  2E9F A;  2PTQ A;  1T6J A;  3R6Y A;  1TJW A;  1YIS A;  2RJS A;  1K62 A;  3CRW 1;  4V2R A;  3GTD A;  2O7E A;  4C5U A;  1XMD A;  1U15 A;  3GZH A;  3OCE A;  3R6Q A;  4BAA A;  2PTS A;  1Z4I A;  2YV5 A;  4V2Q A;  1XWO A;  4MWO A;  3NZ4 A;  2D28 C;  1GK3 A;  1YFE A;  3CI0 K;  1XL7 A;  1RE5 A;  1YFM A;  3NO9 A;  1B8F A;  3QBP A;  4C5S A;  3TV2 A;  2JAW A;  4MUM A;  5M0J A;  4L6C A; 
#chains in the Genus database with same CATH homology
 4EEI A;  1Q5N A;  3R6V A;  1T6P A;  1JSW A;  2QVE A;  2HVG A;  1FUO A;  3BHG A;  4ADL A;  2PTR A;  2VD6 A;  2O7D A;  4APA A;  4HGV A;  1DCN A;  1GKM A;  1TJ7 A;  1TJU A;  2O6Y A;  4APB A;  1GKJ A;  3CZO A;  3OCF A;  4C5R A;  4EFC A;  3KDY A;  5D6B A;  2NYF A;  3UNV A;  1FUP A;  2OHY A;  4CQ5 A;  1I0A A;  2YII A;  2O7B A;  2O78 A;  1GK2 A;  4NSL A;  4MX2 A;  2QGA B;  1TJV A;  1VDK A;  2X75 A;  2O7F A;  3RRP A;  1K7W A;  4FLC A;  4C6G A;  1HY1 A;  1AUW A;  5F91 A;  2FUS A;  5F92 A;  1FUQ A;  1EB4 A;  1HY0 A;  4NLE A;  1U16 A;  1J3U A;  5EYV A;  1W27 A;  3KDZ A;  3RD8 A;  4ADM A;  4FFX A;  1C3U A;  3E04 A;  5HW2 A;  1C3C A;  2RJR A;  4BAB A;  1KQ7 A;  2NYN A;  2PFM A;  1DOF A;  3C8T A;  2J91 A;  5EYT A;  1Y2M A;  1FUR A;  2E9F A;  2PTQ A;  1T6J A;  3R6Y A;  1TJW A;  1YIS A;  2RJS A;  1K62 A;  4V2R A;  3GTD A;  2O7E A;  4C5U A;  1U15 A;  3GZH A;  3OCE A;  3R6Q A;  4BAA A;  2PTS A;  4V2Q A;  1XWO A;  3NZ4 A;  1GK3 A;  1YFE A;  1RE5 A;  1YFM A;  3NO9 A;  1B8F A;  3QBP A;  4C5S A;  3TV2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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