1GKMA

Histidine ammonia-lyase (hal) from pseudomonas putida inhibited with l-cysteine
Total Genus 202
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
202
sequence length
507
structure length
506
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords HISTIDINE AMMONIA-LYASE
publication title Structures of Two Histidine Ammonia-Lyase Modifications and Implications for the Catalytic Mechanism
pubmed doi rcsb
source organism Pseudomonas putida
total genus 202
structure length 506
sequence length 507
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gkmA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gkmA02
5F92A 2O7FA 4EFCA 2PTRA 5HW2A 2VD6A 3GZHA 3TV2A 4V2QA 4CQ5A 4C6GA 2RJRA 5EYVA 3C8TA 4MX2A 3QBPA 1JSWA 5EYTA 2OHYA 2PTSA 1TJ7A 2PTQA 1I0AA 1XWOA 3KDZA 3R6QA 3NO9A 1HY0A 1C3UA 4NLEA 4V2RA 1FURA 1GKJA 1Q5NA 4ADMA 4EEIA 2HVGA 2X75A 2O78A 1U15A 1K62A 3BHGA 1C3CA 1TJWA 1GK3A 3RRPA 2O6YA 4NSLA 1J3UA 1YISA 3E04A 2FUSA 2O7BA 4HGVA 5D6BA 1B8FA 1Y2MA 3RD8A 2PFMA 1FUPA 3OCFA 4FLCA 4APAA 2QVEA 4C5SA 3R6YA 1T6JA 1TJUA 3CZOA 4C5RA 2NYFA 3KDYA 3OCEA 1DCNA 2NYNA 2O7DA 1GK2A 3UNVA 2RJSA 2QGAB 5F91A 3GTDA 4BABA 1HY1A 4BAAA 2YIIA 1U16A 3NZ4A 1VDKA 1EB4A 2O7EA 2J91A 2E9FA 4APBA 1RE5A 1AUWA 4C5UA 1KQ7A 1GKMA 1W27A 4FFXA 4ADLA 1YFMA 1FUOA 1T6PA 1DOFA 3R6VA 1FUQA 1YFEA 1TJVA 1K7WA
chains in the Genus database with same CATH superfamily
5F92A 2O7FA 4EFCA 2PTRA 5HW2A 2VD6A 3GZHA 3TV2A 4V2QA 1XL7A 4CQ5A 4C6GA 2RJRA 4A15A 5EYVA 3C8TA 4MX2A 3QBPA 1JSWA 5EYTA 2OHYA 2PTSA 1TJ7A 2PTQA 2FELA 1XL8A 1I0AA 1XWOA 3KDZA 3R6QA 3NO9A 1HY0A 1C3UA 4NLEA 4V2RA 1FURA 1GKJA 1Q5NA 4ADMA 3CRW1 2VSFA 4EEIA 2HVGA 2X75A 2O78A 1U15A 1K62A 3BHGA 1C3CA 1TJWA 1GK3A 3RRPA 2O6YA 4NSLA 1J3UA 1YISA 3E04A 2FUSA 2O7BA 4HGVA 5D6BA 1B8FA 1Y2MA 3RD8A 2PFMA 1FUPA 3OCFA 4FLCA 4APAA 2QVEA 4C5SA 3R6YA 4WNLA 1T6JA 1TJUA 3CZOA 4C5RA 2NYFA 3KDYA 3OCEA 3CRVA 2FENA 1DCNA 1XMDA 2NYNA 2O7DA 1GK2A 1XLYA 3UNVA 2RJSA 2QGAB 5F91A 5H8WA 3GTDA 4BABA 1HY1A 4BAAA 2YIIA 1U16A 3NZ4A 1VDKA 1EB4A 2O7EA 2J91A 5M0IA 2E9FA 4APBA 1RE5A 1AUWA 4C5UA 5M0JA 1KQ7A 2VL7A 1GKMA 1W27A 4FFXA 4ADLA 1YFMA 1FUOA 1T6PA 1DOFA 1XMCA 3R6VA 1FUQA 1YFEA 1TJVA 1K7WA
chains in the Genus database with same CATH topology
5F92A 2O7FA 4EFCA 2PTRA 5HW2A 2VD6A 3GZHA 3TV2A 4V2QA 4CQ5A 4C6GA 2RJRA 5EYVA 3C8TA 4MX2A 3QBPA 1JSWA 5EYTA 2OHYA 2PTSA 1TJ7A 2PTQA 1I0AA 1XWOA 3KDZA 3R6QA 3NO9A 1HY0A 1C3UA 4NLEA 4V2RA 1FURA 1GKJA 1Q5NA 4ADMA 4EEIA 2HVGA 2X75A 2O78A 1U15A 1K62A 3BHGA 1C3CA 1TJWA 1GK3A 3RRPA 2O6YA 4NSLA 1J3UA 1YISA 3E04A 2FUSA 2O7BA 4HGVA 5D6BA 1B8FA 1Y2MA 3RD8A 2PFMA 1FUPA 3OCFA 4FLCA 4APAA 2QVEA 4C5SA 3R6YA 1T6JA 1TJUA 3CZOA 4C5RA 2NYFA 3KDYA 3OCEA 1DCNA 2NYNA 2O7DA 1GK2A 3UNVA 2RJSA 2QGAB 5F91A 3GTDA 4BABA 1HY1A 4BAAA 2YIIA 1U16A 3NZ4A 1VDKA 1EB4A 2O7EA 2J91A 2E9FA 4APBA 1RE5A 1AUWA 4C5UA 1KQ7A 1GKMA 1W27A 4FFXA 4ADLA 1YFMA 1FUOA 1T6PA 1DOFA 3R6VA 1FUQA 1YFEA 1TJVA 1K7WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F92 A;  2O7F A;  4EFC A;  2PTR A;  5HW2 A;  2VD6 A;  3GZH A;  3TV2 A;  4V2Q A;  4CQ5 A;  4C6G A;  2RJR A;  5EYV A;  3C8T A;  4MX2 A;  3QBP A;  1JSW A;  5EYT A;  2OHY A;  2PTS A;  1TJ7 A;  2PTQ A;  1I0A A;  1XWO A;  3KDZ A;  3R6Q A;  3NO9 A;  1HY0 A;  1C3U A;  4NLE A;  4V2R A;  1FUR A;  1GKJ A;  1Q5N A;  4ADM A;  4EEI A;  2HVG A;  2X75 A;  2O78 A;  1U15 A;  1K62 A;  3BHG A;  1C3C A;  1TJW A;  1GK3 A;  3RRP A;  2O6Y A;  4NSL A;  1J3U A;  1YIS A;  3E04 A;  2FUS A;  2O7B A;  4HGV A;  5D6B A;  1B8F A;  1Y2M A;  3RD8 A;  2PFM A;  1FUP A;  3OCF A;  4FLC A;  4APA A;  2QVE A;  4C5S A;  3R6Y A;  1T6J A;  1TJU A;  3CZO A;  4C5R A;  2NYF A;  3KDY A;  3OCE A;  1DCN A;  2NYN A;  2O7D A;  1GK2 A;  3UNV A;  2RJS A;  2QGA B;  5F91 A;  3GTD A;  4BAB A;  1HY1 A;  4BAA A;  2YII A;  1U16 A;  3NZ4 A;  1VDK A;  1EB4 A;  2O7E A;  2J91 A;  2E9F A;  4APB A;  1RE5 A;  1AUW A;  4C5U A;  1KQ7 A;  1GKM A;  1W27 A;  4FFX A;  4ADL A;  1YFM A;  1FUO A;  1T6P A;  1DOF A;  3R6V A;  1FUQ A;  1YFE A;  1TJV A;  1K7W A; 
#chains in the Genus database with same CATH topology
 5F92 A;  2O7F A;  4EFC A;  2PTR A;  5HW2 A;  2VD6 A;  3GZH A;  3TV2 A;  4V2Q A;  1XL7 A;  4CQ5 A;  4C6G A;  2RJR A;  4A15 A;  5EYV A;  3C8T A;  4MX2 A;  3QBP A;  1JSW A;  5EYT A;  2OHY A;  2PTS A;  1TJ7 A;  2PTQ A;  2FEL A;  1XL8 A;  1I0A A;  1XWO A;  3KDZ A;  3R6Q A;  3NO9 A;  1HY0 A;  1C3U A;  4NLE A;  4V2R A;  1FUR A;  1GKJ A;  1Q5N A;  4ADM A;  3CRW 1;  2VSF A;  4EEI A;  2HVG A;  2X75 A;  2O78 A;  1U15 A;  1K62 A;  3BHG A;  1C3C A;  1TJW A;  1GK3 A;  3RRP A;  2O6Y A;  4NSL A;  1J3U A;  1YIS A;  3E04 A;  2FUS A;  2O7B A;  4HGV A;  5D6B A;  1B8F A;  1Y2M A;  3RD8 A;  2PFM A;  1FUP A;  3OCF A;  4FLC A;  4APA A;  2QVE A;  4C5S A;  3R6Y A;  4WNL A;  1T6J A;  1TJU A;  3CZO A;  4C5R A;  2NYF A;  3KDY A;  3OCE A;  3CRV A;  2FEN A;  1DCN A;  1XMD A;  2NYN A;  2O7D A;  1GK2 A;  1XLY A;  3UNV A;  2RJS A;  2QGA B;  5F91 A;  5H8W A;  3GTD A;  4BAB A;  1HY1 A;  4BAA A;  2YII A;  1U16 A;  3NZ4 A;  1VDK A;  1EB4 A;  2O7E A;  2J91 A;  5M0I A;  2E9F A;  4APB A;  1RE5 A;  1AUW A;  4C5U A;  5M0J A;  1KQ7 A;  2VL7 A;  1GKM A;  1W27 A;  4FFX A;  4ADL A;  1YFM A;  1FUO A;  1T6P A;  1DOF A;  1XMC A;  3R6V A;  1FUQ A;  1YFE A;  1TJV A;  1K7W A; 
#chains in the Genus database with same CATH homology
 5F92 A;  2O7F A;  4EFC A;  2PTR A;  5HW2 A;  2VD6 A;  3GZH A;  3TV2 A;  4V2Q A;  4CQ5 A;  4C6G A;  2RJR A;  5EYV A;  3C8T A;  4MX2 A;  3QBP A;  1JSW A;  5EYT A;  2OHY A;  2PTS A;  1TJ7 A;  2PTQ A;  1I0A A;  1XWO A;  3KDZ A;  3R6Q A;  3NO9 A;  1HY0 A;  1C3U A;  4NLE A;  4V2R A;  1FUR A;  1GKJ A;  1Q5N A;  4ADM A;  4EEI A;  2HVG A;  2X75 A;  2O78 A;  1U15 A;  1K62 A;  3BHG A;  1C3C A;  1TJW A;  1GK3 A;  3RRP A;  2O6Y A;  4NSL A;  1J3U A;  1YIS A;  3E04 A;  2FUS A;  2O7B A;  4HGV A;  5D6B A;  1B8F A;  1Y2M A;  3RD8 A;  2PFM A;  1FUP A;  3OCF A;  4FLC A;  4APA A;  2QVE A;  4C5S A;  3R6Y A;  1T6J A;  1TJU A;  3CZO A;  4C5R A;  2NYF A;  3KDY A;  3OCE A;  1DCN A;  2NYN A;  2O7D A;  1GK2 A;  3UNV A;  2RJS A;  2QGA B;  5F91 A;  3GTD A;  4BAB A;  1HY1 A;  4BAA A;  2YII A;  1U16 A;  3NZ4 A;  1VDK A;  1EB4 A;  2O7E A;  2J91 A;  2E9F A;  4APB A;  1RE5 A;  1AUW A;  4C5U A;  1KQ7 A;  1GKM A;  1W27 A;  4FFX A;  4ADL A;  1YFM A;  1FUO A;  1T6P A;  1DOF A;  3R6V A;  1FUQ A;  1YFE A;  1TJV A;  1K7W A; 
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