1GKMA

Histidine ammonia-lyase (hal) from pseudomonas putida inhibited with l-cysteine
Total Genus 202
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
202
sequence length
507
structure length
506
Chain Sequence
b'TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HISTIDINE AMMONIA-LYASE
publication title Structures of Two Histidine Ammonia-Lyase Modifications and Implications for the Catalytic Mechanism
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
total genus 202
structure length 506
sequence length 507
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gkmA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gkmA02
1B8FA 1Y2MA 4NLEA 1JSWA 3R6QA 3R6VA 3QBPA 4C6GA 2QVEA 4ADMA 4BAAA 1C3CA 2YIIA 4ADLA 1C3UA 4EEIA 4APAA 3RRPA 3E04A 4BABA 2O6YA 2HVGA 4FLCA 4CQ5A 2PTSA 2FUSA 2O7BA 1HY1A 2OHYA 2X75A 4MX2A 1EB4A 1J3UA 5HW2A 4APBA 3R6YA 1RE5A 1T6PA 1FURA 2O7FA 3CZOA 5F92A 1K62A 1DCNA 2QGAB 4V2QA 1YFMA 3C8TA 3GTDA 1AUWA 4C5RA 2O7DA 2RJSA 1K7WA 5F91A 2PTRA 1U15A 1KQ7A 4NSLA 4HGVA 2PFMA 2NYNA 3TV2A 4V2RA 3GZHA 1HY0A 3OCEA 2J91A 2RJRA 1YFEA 2O78A 4C5SA 1TJUA 1FUOA 5EYVA 1T6JA 1FUPA 4C5UA 3BHGA 1GKMA 1W27A 4FFXA 1VDKA 1YISA 1Q5NA 3OCFA 2PTQA 2NYFA 3NO9A 2VD6A 3UNVA 1TJ7A 3KDZA 1TJVA 2E9FA 3NZ4A 5D6BA 1GK3A 1TJWA 1GK2A 4EFCA 5EYTA 1I0AA 1GKJA 1DOFA 1U16A 1XWOA 3RD8A 1FUQA 2O7EA 3KDYA
chains in the Genus database with same CATH superfamily
1B8FA 1Y2MA 4NLEA 1JSWA 3R6QA 3R6VA 2VL7A 3QBPA 4WNLA 4C6GA 2QVEA 4ADMA 4BAAA 2YIIA 1C3CA 4ADLA 1C3UA 4EEIA 4APAA 3RRPA 3E04A 4BABA 2O6YA 2HVGA 4FLCA 4CQ5A 2PTSA 2FUSA 1XL8A 2O7BA 1HY1A 2OHYA 2X75A 4MX2A 4A15A 5M0JA 1EB4A 1J3UA 5HW2A 4APBA 3R6YA 1RE5A 1T6PA 2FELA 1FURA 2O7FA 3CZOA 5F92A 1XMDA 1K62A 1DCNA 2QGAB 4V2QA 1YFMA 1XL7A 3C8TA 1AUWA 3GTDA 4C5RA 2O7DA 2RJSA 1K7WA 5F91A 2PTRA 1U15A 1KQ7A 4NSLA 1XLYA 4HGVA 2PFMA 2NYNA 3TV2A 4V2RA 3GZHA 1HY0A 3OCEA 2FENA 1XMCA 2J91A 2RJRA 1YFEA 2O78A 4C5SA 1TJUA 5H8WA 1FUOA 5EYVA 1T6JA 1FUPA 4C5UA 3BHGA 1GKMA 1W27A 2VSFA 4FFXA 5M0IA 1VDKA 1YISA 1Q5NA 3OCFA 2PTQA 2NYFA 3NO9A 2VD6A 3UNVA 1TJ7A 3CRVA 3KDZA 1TJVA 2E9FA 3NZ4A 5D6BA 1GK3A 1TJWA 1GK2A 4EFCA 5EYTA 1I0AA 1GKJA 1DOFA 1U16A 1XWOA 3RD8A 1FUQA 2O7EA 3KDYA 3CRW1
chains in the Genus database with same CATH topology
1B8FA 1Y2MA 4NLEA 1JSWA 3R6QA 3R6VA 3QBPA 4C6GA 2QVEA 4ADMA 4BAAA 1C3CA 2YIIA 4ADLA 1C3UA 4EEIA 4APAA 3RRPA 3E04A 4BABA 2O6YA 2HVGA 4FLCA 4CQ5A 2PTSA 2FUSA 2O7BA 1HY1A 2OHYA 2X75A 4MX2A 1EB4A 1J3UA 5HW2A 4APBA 3R6YA 1RE5A 1T6PA 1FURA 2O7FA 3CZOA 5F92A 1K62A 1DCNA 2QGAB 4V2QA 1YFMA 3C8TA 3GTDA 1AUWA 4C5RA 2O7DA 2RJSA 1K7WA 5F91A 2PTRA 1U15A 1KQ7A 4NSLA 4HGVA 2PFMA 2NYNA 3TV2A 4V2RA 3GZHA 1HY0A 3OCEA 2J91A 2RJRA 1YFEA 2O78A 4C5SA 1TJUA 1FUOA 5EYVA 1T6JA 1FUPA 4C5UA 3BHGA 1GKMA 1W27A 4FFXA 1VDKA 1YISA 1Q5NA 3OCFA 2PTQA 2NYFA 3NO9A 2VD6A 3UNVA 1TJ7A 3KDZA 1TJVA 2E9FA 3NZ4A 5D6BA 1GK3A 1TJWA 1GK2A 4EFCA 5EYTA 1I0AA 1GKJA 1DOFA 1U16A 1XWOA 3RD8A 1FUQA 2O7EA 3KDYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B8F A;  1Y2M A;  4NLE A;  1JSW A;  3R6Q A;  3R6V A;  3QBP A;  4C6G A;  2QVE A;  4ADM A;  4BAA A;  1C3C A;  2YII A;  4ADL A;  1C3U A;  4EEI A;  4APA A;  3RRP A;  3E04 A;  4BAB A;  2O6Y A;  2HVG A;  4FLC A;  4CQ5 A;  2PTS A;  2FUS A;  2O7B A;  1HY1 A;  2OHY A;  2X75 A;  4MX2 A;  1EB4 A;  1J3U A;  5HW2 A;  4APB A;  3R6Y A;  1RE5 A;  1T6P A;  1FUR A;  2O7F A;  3CZO A;  5F92 A;  1K62 A;  1DCN A;  2QGA B;  4V2Q A;  1YFM A;  3C8T A;  3GTD A;  1AUW A;  4C5R A;  2O7D A;  2RJS A;  1K7W A;  5F91 A;  2PTR A;  1U15 A;  1KQ7 A;  4NSL A;  4HGV A;  2PFM A;  2NYN A;  3TV2 A;  4V2R A;  3GZH A;  1HY0 A;  3OCE A;  2J91 A;  2RJR A;  1YFE A;  2O78 A;  4C5S A;  1TJU A;  1FUO A;  5EYV A;  1T6J A;  1FUP A;  4C5U A;  3BHG A;  1GKM A;  1W27 A;  4FFX A;  1VDK A;  1YIS A;  1Q5N A;  3OCF A;  2PTQ A;  2NYF A;  3NO9 A;  2VD6 A;  3UNV A;  1TJ7 A;  3KDZ A;  1TJV A;  2E9F A;  3NZ4 A;  5D6B A;  1GK3 A;  1TJW A;  1GK2 A;  4EFC A;  5EYT A;  1I0A A;  1GKJ A;  1DOF A;  1U16 A;  1XWO A;  3RD8 A;  1FUQ A;  2O7E A;  3KDY A; 
#chains in the Genus database with same CATH topology
 1B8F A;  1Y2M A;  4NLE A;  1JSW A;  3R6Q A;  3R6V A;  2VL7 A;  3QBP A;  4WNL A;  4C6G A;  2QVE A;  4ADM A;  4BAA A;  2YII A;  1C3C A;  4ADL A;  1C3U A;  4EEI A;  4APA A;  3RRP A;  3E04 A;  4BAB A;  2O6Y A;  2HVG A;  4FLC A;  4CQ5 A;  2PTS A;  2FUS A;  1XL8 A;  2O7B A;  1HY1 A;  2OHY A;  2X75 A;  4MX2 A;  4A15 A;  5M0J A;  1EB4 A;  1J3U A;  5HW2 A;  4APB A;  3R6Y A;  1RE5 A;  1T6P A;  2FEL A;  1FUR A;  2O7F A;  3CZO A;  5F92 A;  1XMD A;  1K62 A;  1DCN A;  2QGA B;  4V2Q A;  1YFM A;  1XL7 A;  3C8T A;  1AUW A;  3GTD A;  4C5R A;  2O7D A;  2RJS A;  1K7W A;  5F91 A;  2PTR A;  1U15 A;  1KQ7 A;  4NSL A;  1XLY A;  4HGV A;  2PFM A;  2NYN A;  3TV2 A;  4V2R A;  3GZH A;  1HY0 A;  3OCE A;  2FEN A;  1XMC A;  2J91 A;  2RJR A;  1YFE A;  2O78 A;  4C5S A;  1TJU A;  5H8W A;  1FUO A;  5EYV A;  1T6J A;  1FUP A;  4C5U A;  3BHG A;  1GKM A;  1W27 A;  2VSF A;  4FFX A;  5M0I A;  1VDK A;  1YIS A;  1Q5N A;  3OCF A;  2PTQ A;  2NYF A;  3NO9 A;  2VD6 A;  3UNV A;  1TJ7 A;  3CRV A;  3KDZ A;  1TJV A;  2E9F A;  3NZ4 A;  5D6B A;  1GK3 A;  1TJW A;  1GK2 A;  4EFC A;  5EYT A;  1I0A A;  1GKJ A;  1DOF A;  1U16 A;  1XWO A;  3RD8 A;  1FUQ A;  2O7E A;  3KDY A;  3CRW 1; 
#chains in the Genus database with same CATH homology
 1B8F A;  1Y2M A;  4NLE A;  1JSW A;  3R6Q A;  3R6V A;  3QBP A;  4C6G A;  2QVE A;  4ADM A;  4BAA A;  1C3C A;  2YII A;  4ADL A;  1C3U A;  4EEI A;  4APA A;  3RRP A;  3E04 A;  4BAB A;  2O6Y A;  2HVG A;  4FLC A;  4CQ5 A;  2PTS A;  2FUS A;  2O7B A;  1HY1 A;  2OHY A;  2X75 A;  4MX2 A;  1EB4 A;  1J3U A;  5HW2 A;  4APB A;  3R6Y A;  1RE5 A;  1T6P A;  1FUR A;  2O7F A;  3CZO A;  5F92 A;  1K62 A;  1DCN A;  2QGA B;  4V2Q A;  1YFM A;  3C8T A;  3GTD A;  1AUW A;  4C5R A;  2O7D A;  2RJS A;  1K7W A;  5F91 A;  2PTR A;  1U15 A;  1KQ7 A;  4NSL A;  4HGV A;  2PFM A;  2NYN A;  3TV2 A;  4V2R A;  3GZH A;  1HY0 A;  3OCE A;  2J91 A;  2RJR A;  1YFE A;  2O78 A;  4C5S A;  1TJU A;  1FUO A;  5EYV A;  1T6J A;  1FUP A;  4C5U A;  3BHG A;  1GKM A;  1W27 A;  4FFX A;  1VDK A;  1YIS A;  1Q5N A;  3OCF A;  2PTQ A;  2NYF A;  3NO9 A;  2VD6 A;  3UNV A;  1TJ7 A;  3KDZ A;  1TJV A;  2E9F A;  3NZ4 A;  5D6B A;  1GK3 A;  1TJW A;  1GK2 A;  4EFC A;  5EYT A;  1I0A A;  1GKJ A;  1DOF A;  1U16 A;  1XWO A;  3RD8 A;  1FUQ A;  2O7E A;  3KDY A; 
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