3OCEA

Crystal structure of fumarate lyase:delta crystallin from brucella melitensis bound to cobalt
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
sequence length
461
structure length
461
Chain Sequence
MTRREQDSLGERDIPMDAYFGIQTLRAVENFSLSDVALNHIPALVRALAMVKKAAATANYKLRQLPEPKYAAIVAACDDIIDGLLMEQFVVDVFQGGAGTSSNMNANEVIANRALEHLGRPRGDYQTIHPNDDVNMSQSTNDVYPTAVRLALLLSQNQVQTALHRLIAAFEAKGREFATVIKIGRTQLQDAVPITLGQEFEAFAATLREDTARLEEVAALFREVNLGGTAIGTRINASHAYAEQAIVELSQISGIELKATGNLVEASWDTGAFVTFSGILRRIAVKLSKIANDLRLLSSGPRSGLGEIRLPAVQPGSSIMPGKVNPVIPESVNQVCYQVIGNDLTVTMAAESGQLQLNAFEPLIVYNILSSMRLLGRAMTNLAERCVDGIEANVERCRAGAEESISLATALVPVVGYARAAEIAKQALASGQTVMEVAISKGLDASALTIMLDPLRMAFPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Fumarate lyase:Delta crystallin
publication title Crystal structure of fumarate lyase:delta crystallin from Brucella melitensis bound to cobalt
rcsb
source organism Brucella melitensis
molecule tags Lyase
total genus 187
structure length 461
sequence length 461
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.1: Aspartate ammonia-lyase.
pdb deposition date 2010-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3oceA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3oceA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3oceA02
1C3UA 1GKJA 5D6BA 2YIIA 1K7WA 3GZHA 4CQ5A 2NYFA 3KDZA 3BHGA 1W27A 4V2QA 1HY0A 3GTDA 5F91A 3UNVA 4ADLA 1YFMA 4NSLA 3NZ4A 1YFEA 2O6YA 2FUSA 2O7EA 5EYTA 2PFMA 3RD8A 5EYVA 1GK2A 1TJVA 1B8FA 1JSWA 3CZOA 4MX2A 4FFXA 1TJWA 4BAAA 2RJRA 5HW2A 1FUPA 4EFCA 3RRPA 1HY1A 2NYNA 3QBPA 1VDKA 2J91A 1FURA 5F92A 1Q5NA 1TJ7A 2QGAB 1Y2MA 2E9FA 2QVEA 1U16A 1T6PA 4APBA 1DCNA 1GKMA 2PTSA 2VD6A 1U15A 1AUWA 1YISA 1J3UA 1KQ7A 1XWOA 3R6YA 2PTQA 1FUQA 2OHYA 4NLEA 3TV2A 3C8TA 1I0AA 2PTRA 3R6QA 3R6VA 1TJUA 2O78A 2RJSA 4C6GA 1K62A 1T6JA 3KDYA 3OCEA 1C3CA 4C5RA 2HVGA 2X75A 4BABA 3OCFA 4C5UA 1FUOA 4HGVA 2O7DA 2O7BA 4ADMA 3E04A 1DOFA 4V2RA 4EEIA 4C5SA 4APAA 1EB4A 1RE5A 2O7FA 3NO9A 4FLCA 1GK3A
chains in the Genus database with same CATH superfamily
1C3UA 1GKJA 5D6BA 2YIIA 2VSFA 3CRW1 1K7WA 3GZHA 3BWVA 4CQ5A 2FELA 1T9HA 2NYFA 2JARA 3KDZA 3BHGA 1XLYA 1W27A 4V2QA 3CI0K 1HY0A 3F4TA 3GTDA 2I7DA 5F91A 3UNVA 4L57A 4ADLA 1YFMA 4NSLA 2YV5A 3NZ4A 4NFLA 1Q92A 1YFEA 2O6YA 5M0JA 2FUSA 2O7EA 1XMDA 5EYTA 2PFMA 3RD8A 5EYVA 1GK2A 1TJVA 4L6AA 1B8FA 1JSWA 3CZOA 1Z4KA 4MUMA 4MX2A 4FFXA 1TJWA 1Z4MA 4BAAA 2RJRA 5HW2A 1FUPA 4EFCA 3RRPA 1Z4PX 1XMCA 2RCNA 1HY1A 4YIKA 2NYNA 3QBPA 2JAOA 1VDKA 2J91A 1FURA 5F92A 1Q5NA 1TJ7A 5M0IA 4MWOA 2QGAB 4L6CA 4A15A 1U0LA 1Y2MA 2E9FA 5H8WA 2QVEA 1U16A 1T6PA 4APBA 1DCNA 1GKMA 1MH9A 2PTSA 4IQJM 2VD6A 1U15A 1AUWA 1YISA 1J3UA 3F4SA 1KQ7A 1XWOA 2JAUA 3R6YA 2PTQA 1FUQA 2OHYA 4NLEA 3F4RA 3TV2A 2D28C 3C8TA 1I0AA 4YIHA 2PTRA 1Z4IA 3U19A 3R6QA 3R6VA 1TJUA 2JAWA 2O78A 2RJSA 4C6GA 1K62A 1T6JA 3KDYA 3OCEA 1XL7A 1C3CA 4C5RA 2HVGA 2D27A 2X75A 4BABA 2VL7A 2FENA 1Z4QA 3OCFA 4C5UA 1FUOA 4HGVA 3CRVA 2O7DA 4E88A 2O7BA 1Z4LA 4ADMA 3E04A 1DOFA 4V2RA 4EEIA 1XL8A 4C5SA 1IW7D 1Q91A 4APAA 1EB4A 4WNLA 1RE5A 3U13A 2O7FA 3NO9A 4FLCA 1GK3A 1Z4JA
chains in the Genus database with same CATH topology
1C3UA 1GKJA 5D6BA 2YIIA 1K7WA 3GZHA 4CQ5A 2NYFA 3KDZA 3BHGA 1W27A 4V2QA 1HY0A 3GTDA 5F91A 3UNVA 4ADLA 1YFMA 4NSLA 3NZ4A 1YFEA 2O6YA 2FUSA 2O7EA 5EYTA 2PFMA 3RD8A 5EYVA 1GK2A 1TJVA 1B8FA 1JSWA 3CZOA 4MX2A 4FFXA 1TJWA 4BAAA 2RJRA 5HW2A 1FUPA 4EFCA 3RRPA 1HY1A 2NYNA 3QBPA 1VDKA 2J91A 1FURA 5F92A 1Q5NA 1TJ7A 2QGAB 1Y2MA 2E9FA 2QVEA 1U16A 1T6PA 4APBA 1DCNA 1GKMA 2PTSA 2VD6A 1U15A 1AUWA 1YISA 1J3UA 1KQ7A 1XWOA 3R6YA 2PTQA 1FUQA 2OHYA 4NLEA 3TV2A 3C8TA 1I0AA 2PTRA 3R6QA 3R6VA 1TJUA 2O78A 2RJSA 4C6GA 1K62A 1T6JA 3KDYA 3OCEA 1C3CA 4C5RA 2HVGA 2X75A 4BABA 3OCFA 4C5UA 1FUOA 4HGVA 2O7DA 2O7BA 4ADMA 3E04A 1DOFA 4V2RA 4EEIA 4C5SA 4APAA 1EB4A 1RE5A 2O7FA 3NO9A 4FLCA 1GK3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C3U A;  1GKJ A;  5D6B A;  2YII A;  1K7W A;  3GZH A;  4CQ5 A;  2NYF A;  3KDZ A;  3BHG A;  1W27 A;  4V2Q A;  1HY0 A;  3GTD A;  5F91 A;  3UNV A;  4ADL A;  1YFM A;  4NSL A;  3NZ4 A;  1YFE A;  2O6Y A;  2FUS A;  2O7E A;  5EYT A;  2PFM A;  3RD8 A;  5EYV A;  1GK2 A;  1TJV A;  1B8F A;  1JSW A;  3CZO A;  4MX2 A;  4FFX A;  1TJW A;  4BAA A;  2RJR A;  5HW2 A;  1FUP A;  4EFC A;  3RRP A;  1HY1 A;  2NYN A;  3QBP A;  1VDK A;  2J91 A;  1FUR A;  5F92 A;  1Q5N A;  1TJ7 A;  2QGA B;  1Y2M A;  2E9F A;  2QVE A;  1U16 A;  1T6P A;  4APB A;  1DCN A;  1GKM A;  2PTS A;  2VD6 A;  1U15 A;  1AUW A;  1YIS A;  1J3U A;  1KQ7 A;  1XWO A;  3R6Y A;  2PTQ A;  1FUQ A;  2OHY A;  4NLE A;  3TV2 A;  3C8T A;  1I0A A;  2PTR A;  3R6Q A;  3R6V A;  1TJU A;  2O78 A;  2RJS A;  4C6G A;  1K62 A;  1T6J A;  3KDY A;  3OCE A;  1C3C A;  4C5R A;  2HVG A;  2X75 A;  4BAB A;  3OCF A;  4C5U A;  1FUO A;  4HGV A;  2O7D A;  2O7B A;  4ADM A;  3E04 A;  1DOF A;  4V2R A;  4EEI A;  4C5S A;  4APA A;  1EB4 A;  1RE5 A;  2O7F A;  3NO9 A;  4FLC A;  1GK3 A; 
#chains in the Genus database with same CATH topology
 1C3U A;  1GKJ A;  5D6B A;  2YII A;  2VSF A;  3CRW 1;  1K7W A;  3GZH A;  3BWV A;  4CQ5 A;  2FEL A;  1T9H A;  2NYF A;  2JAR A;  3KDZ A;  3BHG A;  1XLY A;  1W27 A;  4V2Q A;  3CI0 K;  1HY0 A;  3F4T A;  3GTD A;  2I7D A;  5F91 A;  3UNV A;  4L57 A;  4ADL A;  1YFM A;  4NSL A;  2YV5 A;  3NZ4 A;  4NFL A;  1Q92 A;  1YFE A;  2O6Y A;  5M0J A;  2FUS A;  2O7E A;  1XMD A;  5EYT A;  2PFM A;  3RD8 A;  5EYV A;  1GK2 A;  1TJV A;  4L6A A;  1B8F A;  1JSW A;  3CZO A;  1Z4K A;  4MUM A;  4MX2 A;  4FFX A;  1TJW A;  1Z4M A;  4BAA A;  2RJR A;  5HW2 A;  1FUP A;  4EFC A;  3RRP A;  1Z4P X;  1XMC A;  2RCN A;  1HY1 A;  4YIK A;  2NYN A;  3QBP A;  2JAO A;  1VDK A;  2J91 A;  1FUR A;  5F92 A;  1Q5N A;  1TJ7 A;  5M0I A;  4MWO A;  2QGA B;  4L6C A;  4A15 A;  1U0L A;  1Y2M A;  2E9F A;  5H8W A;  2QVE A;  1U16 A;  1T6P A;  4APB A;  1DCN A;  1GKM A;  1MH9 A;  2PTS A;  4IQJ M;  2VD6 A;  1U15 A;  1AUW A;  1YIS A;  1J3U A;  3F4S A;  1KQ7 A;  1XWO A;  2JAU A;  3R6Y A;  2PTQ A;  1FUQ A;  2OHY A;  4NLE A;  3F4R A;  3TV2 A;  2D28 C;  3C8T A;  1I0A A;  4YIH A;  2PTR A;  1Z4I A;  3U19 A;  3R6Q A;  3R6V A;  1TJU A;  2JAW A;  2O78 A;  2RJS A;  4C6G A;  1K62 A;  1T6J A;  3KDY A;  3OCE A;  1XL7 A;  1C3C A;  4C5R A;  2HVG A;  2D27 A;  2X75 A;  4BAB A;  2VL7 A;  2FEN A;  1Z4Q A;  3OCF A;  4C5U A;  1FUO A;  4HGV A;  3CRV A;  2O7D A;  4E88 A;  2O7B A;  1Z4L A;  4ADM A;  3E04 A;  1DOF A;  4V2R A;  4EEI A;  1XL8 A;  4C5S A;  1IW7 D;  1Q91 A;  4APA A;  1EB4 A;  4WNL A;  1RE5 A;  3U13 A;  2O7F A;  3NO9 A;  4FLC A;  1GK3 A;  1Z4J A; 
#chains in the Genus database with same CATH homology
 1C3U A;  1GKJ A;  5D6B A;  2YII A;  1K7W A;  3GZH A;  4CQ5 A;  2NYF A;  3KDZ A;  3BHG A;  1W27 A;  4V2Q A;  1HY0 A;  3GTD A;  5F91 A;  3UNV A;  4ADL A;  1YFM A;  4NSL A;  3NZ4 A;  1YFE A;  2O6Y A;  2FUS A;  2O7E A;  5EYT A;  2PFM A;  3RD8 A;  5EYV A;  1GK2 A;  1TJV A;  1B8F A;  1JSW A;  3CZO A;  4MX2 A;  4FFX A;  1TJW A;  4BAA A;  2RJR A;  5HW2 A;  1FUP A;  4EFC A;  3RRP A;  1HY1 A;  2NYN A;  3QBP A;  1VDK A;  2J91 A;  1FUR A;  5F92 A;  1Q5N A;  1TJ7 A;  2QGA B;  1Y2M A;  2E9F A;  2QVE A;  1U16 A;  1T6P A;  4APB A;  1DCN A;  1GKM A;  2PTS A;  2VD6 A;  1U15 A;  1AUW A;  1YIS A;  1J3U A;  1KQ7 A;  1XWO A;  3R6Y A;  2PTQ A;  1FUQ A;  2OHY A;  4NLE A;  3TV2 A;  3C8T A;  1I0A A;  2PTR A;  3R6Q A;  3R6V A;  1TJU A;  2O78 A;  2RJS A;  4C6G A;  1K62 A;  1T6J A;  3KDY A;  3OCE A;  1C3C A;  4C5R A;  2HVG A;  2X75 A;  4BAB A;  3OCF A;  4C5U A;  1FUO A;  4HGV A;  2O7D A;  2O7B A;  4ADM A;  3E04 A;  1DOF A;  4V2R A;  4EEI A;  4C5S A;  4APA A;  1EB4 A;  1RE5 A;  2O7F A;  3NO9 A;  4FLC A;  1GK3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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