3OCEA

Crystal structure of fumarate lyase:delta crystallin from brucella melitensis bound to cobalt
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
sequence length
461
structure length
461
Chain Sequence
MTRREQDSLGERDIPMDAYFGIQTLRAVENFSLSDVALNHIPALVRALAMVKKAAATANYKLRQLPEPKYAAIVAACDDIIDGLLMEQFVVDVFQGGAGTSSNMNANEVIANRALEHLGRPRGDYQTIHPNDDVNMSQSTNDVYPTAVRLALLLSQNQVQTALHRLIAAFEAKGREFATVIKIGRTQLQDAVPITLGQEFEAFAATLREDTARLEEVAALFREVNLGGTAIGTRINASHAYAEQAIVELSQISGIELKATGNLVEASWDTGAFVTFSGILRRIAVKLSKIANDLRLLSSGPRSGLGEIRLPAVQPGSSIMPGKVNPVIPESVNQVCYQVIGNDLTVTMAAESGQLQLNAFEPLIVYNILSSMRLLGRAMTNLAERCVDGIEANVERCRAGAEESISLATALVPVVGYARAAEIAKQALASGQTVMEVAISKGLDASALTIMLDPLRMAFPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Fumarate lyase:Delta crystallin
publication title Crystal structure of fumarate lyase:delta crystallin from Brucella melitensis bound to cobalt
rcsb
source organism Brucella melitensis
total genus 187
structure length 461
sequence length 461
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.1: Aspartate ammonia-lyase.
pdb deposition date 2010-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3oceA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3oceA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3oceA02
3R6QA 2FUSA 2E9FA 1YFEA 1AUWA 3NZ4A 2O6YA 1GK3A 4BABA 1I0AA 1GKMA 3GZHA 1J3UA 4EEIA 4FLCA 1TJ7A 3C8TA 1VDKA 1GKJA 3R6YA 2OHYA 1TJWA 1FUPA 4EFCA 5EYTA 1YFMA 3OCEA 4V2QA 1TJVA 2J91A 3CZOA 2NYNA 2O78A 3BHGA 1HY1A 1K62A 4C5SA 2PTQA 2YIIA 3KDZA 4ADLA 2O7DA 3RRPA 3NO9A 2NYFA 1FURA 4V2RA 1EB4A 4HGVA 2RJSA 3R6VA 5F91A 4ADMA 1YISA 5F92A 1C3CA 1K7WA 1W27A 4C5UA 4NLEA 2PFMA 2PTSA 5HW2A 2QGAB 2RJRA 5D6BA 1XWOA 1U15A 4MX2A 1C3UA 3GTDA 3UNVA 3RD8A 2O7EA 1Y2MA 1KQ7A 2O7BA 1T6JA 4BAAA 1DOFA 3OCFA 1HY0A 3KDYA 4APBA 1TJUA 2O7FA 4C6GA 3QBPA 1GK2A 3TV2A 1RE5A 1Q5NA 1JSWA 1FUOA 1T6PA 3E04A 5EYVA 1U16A 4CQ5A 2X75A 1DCNA 2VD6A 2QVEA 1FUQA 4NSLA 4FFXA 1B8FA 2PTRA 4C5RA 4APAA 2HVGA
chains in the Genus database with same CATH superfamily
3R6QA 2FUSA 1IW7D 2E9FA 1YFEA 2JAOA 1AUWA 3NZ4A 2O6YA 1GK3A 5M0JA 4BABA 3BWVA 1I0AA 3CI0K 1GKMA 3GZHA 4MUMA 1J3UA 4EEIA 4FLCA 1TJ7A 1XMCA 3C8TA 1VDKA 1GKJA 3R6YA 3F4RA 1TJWA 2OHYA 3CRW1 1FUPA 4E88A 2JARA 4EFCA 5EYTA 1YFMA 2YV5A 1U0LA 2D28C 3OCEA 4V2QA 1TJVA 2J91A 4YIHA 3CZOA 1Z4QA 1XMDA 2NYNA 2O78A 1Z4KA 3BHGA 1HY1A 1K62A 4C5SA 4NFLA 4L57A 2PTQA 1XL8A 2YIIA 4MWOA 3KDZA 4ADLA 2O7DA 5H8WA 3RRPA 2FENA 3NO9A 1XL7A 2NYFA 1FURA 4V2RA 1EB4A 4HGVA 2RJSA 1Z4MA 3R6VA 5F91A 4ADMA 1YISA 5F92A 1C3CA 1K7WA 2JAWA 1W27A 4C5UA 4NLEA 2PFMA 2VL7A 2PTSA 5HW2A 2QGAB 2FELA 2RJRA 4L6AA 2D27A 1XWOA 5D6BA 1XLYA 1U15A 4MX2A 1C3UA 3GTDA 3UNVA 3RD8A 1MH9A 2O7EA 1Y2MA 1KQ7A 2O7BA 1T6JA 1Z4LA 4BAAA 1DOFA 3F4TA 3OCFA 1HY0A 3U19A 4APBA 1TJUA 3KDYA 5M0IA 2O7FA 2VSFA 4C6GA 1Q91A 1Q92A 3QBPA 1GK2A 3TV2A 1RE5A 1Q5NA 1JSWA 1FUOA 1T6PA 2JAUA 3E04A 5EYVA 4L6CA 4A15A 1Z4IA 1U16A 4CQ5A 2X75A 1DCNA 2RCNA 2VD6A 3F4SA 2QVEA 2I7DA 1Z4PX 1FUQA 4IQJM 1T9HA 4NSLA 3U13A 4FFXA 3CRVA 4YIKA 4WNLA 1Z4JA 1B8FA 2PTRA 4C5RA 4APAA 2HVGA
chains in the Genus database with same CATH topology
3R6QA 2FUSA 2E9FA 1YFEA 1AUWA 3NZ4A 2O6YA 1GK3A 4BABA 1I0AA 1GKMA 3GZHA 1J3UA 4EEIA 4FLCA 1TJ7A 3C8TA 1VDKA 1GKJA 3R6YA 2OHYA 1TJWA 1FUPA 4EFCA 5EYTA 1YFMA 3OCEA 4V2QA 1TJVA 2J91A 3CZOA 2NYNA 2O78A 3BHGA 1HY1A 1K62A 4C5SA 2PTQA 2YIIA 3KDZA 4ADLA 2O7DA 3RRPA 3NO9A 2NYFA 1FURA 4V2RA 1EB4A 4HGVA 2RJSA 3R6VA 5F91A 4ADMA 1YISA 5F92A 1C3CA 1K7WA 1W27A 4C5UA 4NLEA 2PFMA 2PTSA 5HW2A 2QGAB 2RJRA 5D6BA 1XWOA 1U15A 4MX2A 1C3UA 3GTDA 3UNVA 3RD8A 2O7EA 1Y2MA 1KQ7A 2O7BA 1T6JA 4BAAA 1DOFA 3OCFA 1HY0A 3KDYA 4APBA 1TJUA 2O7FA 4C6GA 3QBPA 1GK2A 3TV2A 1RE5A 1Q5NA 1JSWA 1FUOA 1T6PA 3E04A 5EYVA 1U16A 4CQ5A 2X75A 1DCNA 2VD6A 2QVEA 1FUQA 4NSLA 4FFXA 1B8FA 2PTRA 4C5RA 4APAA 2HVGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R6Q A;  2FUS A;  2E9F A;  1YFE A;  1AUW A;  3NZ4 A;  2O6Y A;  1GK3 A;  4BAB A;  1I0A A;  1GKM A;  3GZH A;  1J3U A;  4EEI A;  4FLC A;  1TJ7 A;  3C8T A;  1VDK A;  1GKJ A;  3R6Y A;  2OHY A;  1TJW A;  1FUP A;  4EFC A;  5EYT A;  1YFM A;  3OCE A;  4V2Q A;  1TJV A;  2J91 A;  3CZO A;  2NYN A;  2O78 A;  3BHG A;  1HY1 A;  1K62 A;  4C5S A;  2PTQ A;  2YII A;  3KDZ A;  4ADL A;  2O7D A;  3RRP A;  3NO9 A;  2NYF A;  1FUR A;  4V2R A;  1EB4 A;  4HGV A;  2RJS A;  3R6V A;  5F91 A;  4ADM A;  1YIS A;  5F92 A;  1C3C A;  1K7W A;  1W27 A;  4C5U A;  4NLE A;  2PFM A;  2PTS A;  5HW2 A;  2QGA B;  2RJR A;  5D6B A;  1XWO A;  1U15 A;  4MX2 A;  1C3U A;  3GTD A;  3UNV A;  3RD8 A;  2O7E A;  1Y2M A;  1KQ7 A;  2O7B A;  1T6J A;  4BAA A;  1DOF A;  3OCF A;  1HY0 A;  3KDY A;  4APB A;  1TJU A;  2O7F A;  4C6G A;  3QBP A;  1GK2 A;  3TV2 A;  1RE5 A;  1Q5N A;  1JSW A;  1FUO A;  1T6P A;  3E04 A;  5EYV A;  1U16 A;  4CQ5 A;  2X75 A;  1DCN A;  2VD6 A;  2QVE A;  1FUQ A;  4NSL A;  4FFX A;  1B8F A;  2PTR A;  4C5R A;  4APA A;  2HVG A; 
#chains in the Genus database with same CATH topology
 3R6Q A;  2FUS A;  1IW7 D;  2E9F A;  1YFE A;  2JAO A;  1AUW A;  3NZ4 A;  2O6Y A;  1GK3 A;  5M0J A;  4BAB A;  3BWV A;  1I0A A;  3CI0 K;  1GKM A;  3GZH A;  4MUM A;  1J3U A;  4EEI A;  4FLC A;  1TJ7 A;  1XMC A;  3C8T A;  1VDK A;  1GKJ A;  3R6Y A;  3F4R A;  1TJW A;  2OHY A;  3CRW 1;  1FUP A;  4E88 A;  2JAR A;  4EFC A;  5EYT A;  1YFM A;  2YV5 A;  1U0L A;  2D28 C;  3OCE A;  4V2Q A;  1TJV A;  2J91 A;  4YIH A;  3CZO A;  1Z4Q A;  1XMD A;  2NYN A;  2O78 A;  1Z4K A;  3BHG A;  1HY1 A;  1K62 A;  4C5S A;  4NFL A;  4L57 A;  2PTQ A;  1XL8 A;  2YII A;  4MWO A;  3KDZ A;  4ADL A;  2O7D A;  5H8W A;  3RRP A;  2FEN A;  3NO9 A;  1XL7 A;  2NYF A;  1FUR A;  4V2R A;  1EB4 A;  4HGV A;  2RJS A;  1Z4M A;  3R6V A;  5F91 A;  4ADM A;  1YIS A;  5F92 A;  1C3C A;  1K7W A;  2JAW A;  1W27 A;  4C5U A;  4NLE A;  2PFM A;  2VL7 A;  2PTS A;  5HW2 A;  2QGA B;  2FEL A;  2RJR A;  4L6A A;  2D27 A;  1XWO A;  5D6B A;  1XLY A;  1U15 A;  4MX2 A;  1C3U A;  3GTD A;  3UNV A;  3RD8 A;  1MH9 A;  2O7E A;  1Y2M A;  1KQ7 A;  2O7B A;  1T6J A;  1Z4L A;  4BAA A;  1DOF A;  3F4T A;  3OCF A;  1HY0 A;  3U19 A;  4APB A;  1TJU A;  3KDY A;  5M0I A;  2O7F A;  2VSF A;  4C6G A;  1Q91 A;  1Q92 A;  3QBP A;  1GK2 A;  3TV2 A;  1RE5 A;  1Q5N A;  1JSW A;  1FUO A;  1T6P A;  2JAU A;  3E04 A;  5EYV A;  4L6C A;  4A15 A;  1Z4I A;  1U16 A;  4CQ5 A;  2X75 A;  1DCN A;  2RCN A;  2VD6 A;  3F4S A;  2QVE A;  2I7D A;  1Z4P X;  1FUQ A;  4IQJ M;  1T9H A;  4NSL A;  3U13 A;  4FFX A;  3CRV A;  4YIK A;  4WNL A;  1Z4J A;  1B8F A;  2PTR A;  4C5R A;  4APA A;  2HVG A; 
#chains in the Genus database with same CATH homology
 3R6Q A;  2FUS A;  2E9F A;  1YFE A;  1AUW A;  3NZ4 A;  2O6Y A;  1GK3 A;  4BAB A;  1I0A A;  1GKM A;  3GZH A;  1J3U A;  4EEI A;  4FLC A;  1TJ7 A;  3C8T A;  1VDK A;  1GKJ A;  3R6Y A;  2OHY A;  1TJW A;  1FUP A;  4EFC A;  5EYT A;  1YFM A;  3OCE A;  4V2Q A;  1TJV A;  2J91 A;  3CZO A;  2NYN A;  2O78 A;  3BHG A;  1HY1 A;  1K62 A;  4C5S A;  2PTQ A;  2YII A;  3KDZ A;  4ADL A;  2O7D A;  3RRP A;  3NO9 A;  2NYF A;  1FUR A;  4V2R A;  1EB4 A;  4HGV A;  2RJS A;  3R6V A;  5F91 A;  4ADM A;  1YIS A;  5F92 A;  1C3C A;  1K7W A;  1W27 A;  4C5U A;  4NLE A;  2PFM A;  2PTS A;  5HW2 A;  2QGA B;  2RJR A;  5D6B A;  1XWO A;  1U15 A;  4MX2 A;  1C3U A;  3GTD A;  3UNV A;  3RD8 A;  2O7E A;  1Y2M A;  1KQ7 A;  2O7B A;  1T6J A;  4BAA A;  1DOF A;  3OCF A;  1HY0 A;  3KDY A;  4APB A;  1TJU A;  2O7F A;  4C6G A;  3QBP A;  1GK2 A;  3TV2 A;  1RE5 A;  1Q5N A;  1JSW A;  1FUO A;  1T6P A;  3E04 A;  5EYV A;  1U16 A;  4CQ5 A;  2X75 A;  1DCN A;  2VD6 A;  2QVE A;  1FUQ A;  4NSL A;  4FFX A;  1B8F A;  2PTR A;  4C5R A;  4APA A;  2HVG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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