2E9FA

Crystal structure of t.th.hb8 argininosuccinate lyase complexed with l-arginine
Total Genus 168
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
449
structure length
449
Chain Sequence
PDALAARFNASLAFDRALWREDLWQNRVHARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFPWREELEDVHMNLEARLTELVGPPGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHFTARELGFKAPMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEELILYSTEEFGFVEVPDAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGLPLAYNKDLQEDKEPLLDALATYRDSLRLLAALLPGLKWRRERMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEEGRALKDLTLEELQAHHPLFAEDALPLLRLETAIHRRRSYGGTAPEAVRERLEEAKKEVGLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Argininosuccinate lyase
publication title Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine
rcsb
source organism Thermus thermophilus
molecule tags Lyase
total genus 168
structure length 449
sequence length 449
chains with identical sequence B, C, D
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2007-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2e9fA03
1.10.275.50 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase C; Chain B, domain 1 2e9fA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2e9fA02
4MX2A 1HY1A 1XWOA 2X75A 3NZ4A 4CQ5A 4FLCA 2O6YA 1Y2MA 2J91A 3R6QA 2PFMA 1AUWA 2VD6A 2O78A 1GKJA 3RD8A 4C5SA 2PTQA 4V2QA 1T6PA 1GKMA 5HW2A 1EB4A 1YFMA 4C5UA 2YIIA 5D6BA 1T6JA 5EYVA 1I0AA 1RE5A 2RJSA 2O7BA 2HVGA 1DCNA 4V2RA 3TV2A 1FUPA 3E04A 4NLEA 1FUQA 2QVEA 4BAAA 1TJ7A 3NO9A 4EEIA 1J3UA 1JSWA 1GK3A 1HY0A 1TJVA 3KDYA 1FURA 4HGVA 1TJUA 5F91A 1DOFA 3C8TA 3UNVA 2PTSA 2O7EA 3RRPA 4ADLA 4ADMA 1C3CA 3OCEA 4NSLA 1W27A 5EYTA 1U16A 4FFXA 3GZHA 4C5RA 3QBPA 2PTRA 2E9FA 2O7DA 3R6VA 2NYNA 4C6GA 1K62A 1TJWA 4APBA 2OHYA 1B8FA 2RJRA 2O7FA 1Q5NA 1U15A 1VDKA 1YISA 5F92A 1YFEA 1C3UA 2NYFA 3GTDA 4BABA 1FUOA 3BHGA 3CZOA 4APAA 3KDZA 2QGAB 1GK2A 4EFCA 1K7WA 1KQ7A 3R6YA 3OCFA 2FUSA
chains in the Genus database with same CATH superfamily
4MX2A 1HY1A 1XWOA 2X75A 3NZ4A 2FELA 4CQ5A 4FLCA 2O6YA 1Y2MA 2J91A 1T9HA 3R6QA 2PFMA 1AUWA 2VD6A 2O78A 1MH9A 1Z4JA 1GKJA 3RD8A 4YIHA 3F4TA 4C5SA 4A15A 2YV5A 2PTQA 4V2QA 3CI0K 1T6PA 1Z4PX 1GKMA 5HW2A 3CRVA 3CRW1 5H8WA 1Z4MA 1EB4A 1YFMA 2D28C 4C5UA 4L6CA 4MUMA 2RCNA 2VL7A 2YIIA 5D6BA 1T6JA 5EYVA 1I0AA 1RE5A 2RJSA 2O7BA 1XMCA 1Q92A 2HVGA 1DCNA 2JARA 3F4RA 4V2RA 3TV2A 1FUPA 1XL8A 1IW7D 3E04A 4NLEA 4NFLA 4YIKA 1FUQA 2QVEA 2JAUA 4MWOA 3BWVA 4BAAA 1Z4IA 1TJ7A 3NO9A 4EEIA 1J3UA 1JSWA 1GK3A 1HY0A 2JAOA 1TJVA 3KDYA 1FURA 1Z4LA 3F4SA 2I7DA 4HGVA 1TJUA 4L57A 5F91A 5M0IA 4L6AA 4WNLA 1XLYA 1DOFA 3C8TA 3UNVA 2PTSA 2O7EA 2FENA 1Z4QA 3RRPA 4ADLA 4ADMA 1C3CA 3OCEA 4NSLA 1W27A 5EYTA 1U16A 4FFXA 3GZHA 2D27A 4C5RA 3QBPA 2PTRA 2E9FA 2O7DA 5M0JA 3R6VA 2NYNA 1XL7A 3U19A 4C6GA 1K62A 1TJWA 4APBA 2OHYA 2JAWA 1U0LA 4IQJM 1B8FA 2RJRA 1XMDA 2O7FA 1Q5NA 1Q91A 1U15A 4E88A 1VDKA 1YISA 3U13A 5F92A 1YFEA 2VSFA 1C3UA 2NYFA 3GTDA 4BABA 1Z4KA 1FUOA 3BHGA 3CZOA 4APAA 3KDZA 2QGAB 1GK2A 4EFCA 1K7WA 1KQ7A 3R6YA 3OCFA 2FUSA
chains in the Genus database with same CATH topology
4MX2A 1HY1A 1XWOA 2X75A 3NZ4A 4CQ5A 4FLCA 2O6YA 1Y2MA 2J91A 3R6QA 2PFMA 1AUWA 2VD6A 2O78A 1GKJA 3RD8A 4A15A 4C5SA 2PTQA 4V2QA 1T6PA 1GKMA 5HW2A 3CRVA 3CRW1 5H8WA 1EB4A 1YFMA 4C5UA 2VL7A 2YIIA 5D6BA 1T6JA 5EYVA 1I0AA 1RE5A 2RJSA 2O7BA 1XMCA 2HVGA 1DCNA 4V2RA 3TV2A 1FUPA 1XL8A 3E04A 4NLEA 1FUQA 2QVEA 4BAAA 1TJ7A 3NO9A 4EEIA 1J3UA 1JSWA 1GK3A 1HY0A 1TJVA 3KDYA 1FURA 4HGVA 1TJUA 5F91A 1DOFA 3C8TA 3UNVA 2PTSA 2O7EA 3RRPA 4ADLA 4ADMA 1C3CA 3OCEA 4NSLA 1W27A 5EYTA 1U16A 4FFXA 3GZHA 4C5RA 3QBPA 2PTRA 2E9FA 2O7DA 3R6VA 2NYNA 1XL7A 4C6GA 1K62A 1TJWA 4APBA 2OHYA 1B8FA 2RJRA 1XMDA 2O7FA 1Q5NA 1U15A 1VDKA 1YISA 5F92A 1YFEA 2VSFA 1C3UA 2NYFA 3GTDA 4BABA 1FUOA 3BHGA 3CZOA 4APAA 3KDZA 2QGAB 1GK2A 4EFCA 1K7WA 1KQ7A 3R6YA 3OCFA 2FUSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MX2 A;  1HY1 A;  1XWO A;  2X75 A;  3NZ4 A;  4CQ5 A;  4FLC A;  2O6Y A;  1Y2M A;  2J91 A;  3R6Q A;  2PFM A;  1AUW A;  2VD6 A;  2O78 A;  1GKJ A;  3RD8 A;  4C5S A;  2PTQ A;  4V2Q A;  1T6P A;  1GKM A;  5HW2 A;  1EB4 A;  1YFM A;  4C5U A;  2YII A;  5D6B A;  1T6J A;  5EYV A;  1I0A A;  1RE5 A;  2RJS A;  2O7B A;  2HVG A;  1DCN A;  4V2R A;  3TV2 A;  1FUP A;  3E04 A;  4NLE A;  1FUQ A;  2QVE A;  4BAA A;  1TJ7 A;  3NO9 A;  4EEI A;  1J3U A;  1JSW A;  1GK3 A;  1HY0 A;  1TJV A;  3KDY A;  1FUR A;  4HGV A;  1TJU A;  5F91 A;  1DOF A;  3C8T A;  3UNV A;  2PTS A;  2O7E A;  3RRP A;  4ADL A;  4ADM A;  1C3C A;  3OCE A;  4NSL A;  1W27 A;  5EYT A;  1U16 A;  4FFX A;  3GZH A;  4C5R A;  3QBP A;  2PTR A;  2E9F A;  2O7D A;  3R6V A;  2NYN A;  4C6G A;  1K62 A;  1TJW A;  4APB A;  2OHY A;  1B8F A;  2RJR A;  2O7F A;  1Q5N A;  1U15 A;  1VDK A;  1YIS A;  5F92 A;  1YFE A;  1C3U A;  2NYF A;  3GTD A;  4BAB A;  1FUO A;  3BHG A;  3CZO A;  4APA A;  3KDZ A;  2QGA B;  1GK2 A;  4EFC A;  1K7W A;  1KQ7 A;  3R6Y A;  3OCF A;  2FUS A; 
#chains in the Genus database with same CATH topology
 4MX2 A;  1HY1 A;  1XWO A;  2X75 A;  3NZ4 A;  2FEL A;  4CQ5 A;  4FLC A;  2O6Y A;  1Y2M A;  2J91 A;  1T9H A;  3R6Q A;  2PFM A;  1AUW A;  2VD6 A;  2O78 A;  1MH9 A;  1Z4J A;  1GKJ A;  3RD8 A;  4YIH A;  3F4T A;  4C5S A;  4A15 A;  2YV5 A;  2PTQ A;  4V2Q A;  3CI0 K;  1T6P A;  1Z4P X;  1GKM A;  5HW2 A;  3CRV A;  3CRW 1;  5H8W A;  1Z4M A;  1EB4 A;  1YFM A;  2D28 C;  4C5U A;  4L6C A;  4MUM A;  2RCN A;  2VL7 A;  2YII A;  5D6B A;  1T6J A;  5EYV A;  1I0A A;  1RE5 A;  2RJS A;  2O7B A;  1XMC A;  1Q92 A;  2HVG A;  1DCN A;  2JAR A;  3F4R A;  4V2R A;  3TV2 A;  1FUP A;  1XL8 A;  1IW7 D;  3E04 A;  4NLE A;  4NFL A;  4YIK A;  1FUQ A;  2QVE A;  2JAU A;  4MWO A;  3BWV A;  4BAA A;  1Z4I A;  1TJ7 A;  3NO9 A;  4EEI A;  1J3U A;  1JSW A;  1GK3 A;  1HY0 A;  2JAO A;  1TJV A;  3KDY A;  1FUR A;  1Z4L A;  3F4S A;  2I7D A;  4HGV A;  1TJU A;  4L57 A;  5F91 A;  5M0I A;  4L6A A;  4WNL A;  1XLY A;  1DOF A;  3C8T A;  3UNV A;  2PTS A;  2O7E A;  2FEN A;  1Z4Q A;  3RRP A;  4ADL A;  4ADM A;  1C3C A;  3OCE A;  4NSL A;  1W27 A;  5EYT A;  1U16 A;  4FFX A;  3GZH A;  2D27 A;  4C5R A;  3QBP A;  2PTR A;  2E9F A;  2O7D A;  5M0J A;  3R6V A;  2NYN A;  1XL7 A;  3U19 A;  4C6G A;  1K62 A;  1TJW A;  4APB A;  2OHY A;  2JAW A;  1U0L A;  4IQJ M;  1B8F A;  2RJR A;  1XMD A;  2O7F A;  1Q5N A;  1Q91 A;  1U15 A;  4E88 A;  1VDK A;  1YIS A;  3U13 A;  5F92 A;  1YFE A;  2VSF A;  1C3U A;  2NYF A;  3GTD A;  4BAB A;  1Z4K A;  1FUO A;  3BHG A;  3CZO A;  4APA A;  3KDZ A;  2QGA B;  1GK2 A;  4EFC A;  1K7W A;  1KQ7 A;  3R6Y A;  3OCF A;  2FUS A; 
#chains in the Genus database with same CATH homology
 4MX2 A;  1HY1 A;  1XWO A;  2X75 A;  3NZ4 A;  4CQ5 A;  4FLC A;  2O6Y A;  1Y2M A;  2J91 A;  3R6Q A;  2PFM A;  1AUW A;  2VD6 A;  2O78 A;  1GKJ A;  3RD8 A;  4A15 A;  4C5S A;  2PTQ A;  4V2Q A;  1T6P A;  1GKM A;  5HW2 A;  3CRV A;  3CRW 1;  5H8W A;  1EB4 A;  1YFM A;  4C5U A;  2VL7 A;  2YII A;  5D6B A;  1T6J A;  5EYV A;  1I0A A;  1RE5 A;  2RJS A;  2O7B A;  1XMC A;  2HVG A;  1DCN A;  4V2R A;  3TV2 A;  1FUP A;  1XL8 A;  3E04 A;  4NLE A;  1FUQ A;  2QVE A;  4BAA A;  1TJ7 A;  3NO9 A;  4EEI A;  1J3U A;  1JSW A;  1GK3 A;  1HY0 A;  1TJV A;  3KDY A;  1FUR A;  4HGV A;  1TJU A;  5F91 A;  1DOF A;  3C8T A;  3UNV A;  2PTS A;  2O7E A;  3RRP A;  4ADL A;  4ADM A;  1C3C A;  3OCE A;  4NSL A;  1W27 A;  5EYT A;  1U16 A;  4FFX A;  3GZH A;  4C5R A;  3QBP A;  2PTR A;  2E9F A;  2O7D A;  3R6V A;  2NYN A;  1XL7 A;  4C6G A;  1K62 A;  1TJW A;  4APB A;  2OHY A;  1B8F A;  2RJR A;  1XMD A;  2O7F A;  1Q5N A;  1U15 A;  1VDK A;  1YIS A;  5F92 A;  1YFE A;  2VSF A;  1C3U A;  2NYF A;  3GTD A;  4BAB A;  1FUO A;  3BHG A;  3CZO A;  4APA A;  3KDZ A;  2QGA B;  1GK2 A;  4EFC A;  1K7W A;  1KQ7 A;  3R6Y A;  3OCF A;  2FUS A; 
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similar chains in the pdb database (?% sequence similarity)

 
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