2E9FA

Crystal structure of t.th.hb8 argininosuccinate lyase complexed with l-arginine
Total Genus 168
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
449
structure length
449
Chain Sequence
PDALAARFNASLAFDRALWREDLWQNRVHARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFPWREELEDVHMNLEARLTELVGPPGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHFTARELGFKAPMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEELILYSTEEFGFVEVPDAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGLPLAYNKDLQEDKEPLLDALATYRDSLRLLAALLPGLKWRRERMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEEGRALKDLTLEELQAHHPLFAEDALPLLRLETAIHRRRSYGGTAPEAVRERLEEAKKEVGLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine
rcsb
molecule keywords Argininosuccinate lyase
molecule tags Lyase
source organism Thermus thermophilus
total genus 168
structure length 449
sequence length 449
chains with identical sequence B, C, D
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2007-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2e9fA03
1.10.275.50 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase C; Chain B, domain 1 2e9fA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2e9fA02
2O78A 1KQ7A 2QVEA 1HY0A 1YFEA 1B8FA 3NZ4A 1YFMA 4HGVA 4V2RA 2PTQA 3R6QA 1Q5NA 2O7BA 1I0AA 2VD6A 4APBA 4FLCA 2O7DA 4C5SA 4C5RA 2HVGA 3R6YA 3RRPA 2J91A 3BHGA 1EB4A 1AUWA 1C3UA 4C5UA 1FUQA 1K7WA 2O6YA 1Y2MA 4CQ5A 1YISA 2X75A 3GZHA 1JSWA 1XWOA 3GTDA 1VDKA 2PTRA 2RJSA 2OHYA 3UNVA 1TJWA 3TV2A 1TJVA 1DCNA 4MX2A 3KDYA 4BAAA 2NYNA 4BABA 2NYFA 4V2QA 3R6VA 2FUSA 4NSLA 3QBPA 4C6GA 1C3CA 2YIIA 4EFCA 2PTSA 1U15A 1U16A 3KDZA 3CZOA 1K62A 3C8TA 1GK3A 3NO9A 1TJUA 5D6BA 5F92A 3OCFA 2RJRA 5F91A 1DOFA 1J3UA 4NLEA 1FURA 4FFXA 1RE5A 3OCEA 5EYVA 4APAA 5HW2A 4ADLA 1T6PA 5EYTA 1FUOA 4EEIA 2O7FA 1W27A 3RD8A 1T6JA 4ADMA 2O7EA 3E04A 2PFMA 1GKMA 1FUPA 1TJ7A 1GKJA 2E9FA 1HY1A 1GK2A 2QGAB
chains in the Genus database with same CATH superfamily
1Z4IA 2O78A 4YIHA 1KQ7A 2QVEA 1HY0A 1YFEA 1GK2A 1B8FA 3NZ4A 1YFMA 4HGVA 1MH9A 1U0LA 4V2RA 2PTQA 1XMDA 3R6QA 3F4RA 2VL7A 4L57A 1Q5NA 2O7BA 1I0AA 2VD6A 2FELA 4APBA 4FLCA 2O7DA 4C5SA 4C5RA 2HVGA 3R6YA 3RRPA 1Z4PX 2J91A 3BHGA 1AUWA 1EB4A 1C3UA 4C5UA 3CRW1 1FUQA 1K7WA 2O6YA 2JAOA 1XMCA 2I7DA 1IW7D 1Y2MA 4CQ5A 1YISA 2X75A 3GZHA 1Z4KA 1JSWA 1XWOA 3CI0K 4L6AA 4E88A 3GTDA 1VDKA 2PTRA 2RJSA 2RCNA 2OHYA 3UNVA 1TJWA 4MWOA 3TV2A 1TJVA 1DCNA 4MX2A 1Q91A 3KDYA 3U13A 4BAAA 2NYNA 4BABA 1Z4QA 2NYFA 4V2QA 2D28C 3R6VA 3U19A 2FUSA 2JAWA 3QBPA 4NSLA 3F4SA 1Z4LA 3BWVA 4A15A 4C6GA 1C3CA 2YIIA 2JAUA 4EFCA 1U15A 1U16A 3KDZA 3CZOA 1K62A 3C8TA 1GK3A 5M0IA 3NO9A 1TJUA 5D6BA 5F92A 3OCFA 2RJRA 5F91A 1Z4JA 1DOFA 1J3UA 4NLEA 1FURA 4FFXA 1RE5A 4WNLA 3OCEA 3F4TA 4MUMA 1Q92A 5EYVA 4APAA 1XL7A 4L6CA 5HW2A 4ADLA 1Z4MA 1T6PA 4IQJM 2FENA 5EYTA 4NFLA 1FUOA 1XLYA 4EEIA 2O7FA 2JARA 1XL8A 4YIKA 2VSFA 2YV5A 1T9HA 2D27A 1W27A 3RD8A 1T6JA 4ADMA 2O7EA 3E04A 3CRVA 2PFMA 1GKMA 1FUPA 1TJ7A 5M0JA 1GKJA 5H8WA 2E9FA 1HY1A 2PTSA 2QGAB
chains in the Genus database with same CATH topology
2O78A 1KQ7A 2QVEA 1HY0A 1YFEA 1GK2A 1B8FA 3NZ4A 1YFMA 4HGVA 4V2RA 2PTQA 1XMDA 3R6QA 2VL7A 1Q5NA 2O7BA 1I0AA 2VD6A 4APBA 4FLCA 2O7DA 4C5SA 4C5RA 2HVGA 3R6YA 3RRPA 2J91A 3BHGA 1AUWA 1EB4A 1C3UA 4C5UA 3CRW1 1FUQA 1K7WA 2O6YA 1XMCA 1Y2MA 4CQ5A 1YISA 2X75A 3GZHA 1JSWA 1XWOA 3GTDA 1VDKA 2PTRA 2RJSA 2OHYA 3UNVA 1TJWA 3TV2A 1TJVA 1DCNA 4MX2A 3KDYA 4BAAA 2NYNA 4BABA 2NYFA 4V2QA 3R6VA 2FUSA 4NSLA 3QBPA 4A15A 4C6GA 1C3CA 2YIIA 4EFCA 1U15A 1U16A 3KDZA 3CZOA 1K62A 3C8TA 1GK3A 3NO9A 1TJUA 5D6BA 5F92A 3OCFA 2RJRA 5F91A 1DOFA 1J3UA 4NLEA 1FURA 4FFXA 1RE5A 3OCEA 5EYVA 1XL7A 4APAA 5HW2A 4ADLA 1T6PA 5EYTA 1FUOA 4EEIA 2O7FA 1XL8A 2VSFA 1W27A 3RD8A 1T6JA 4ADMA 2O7EA 3E04A 3CRVA 2PFMA 1GKMA 1FUPA 1TJ7A 1GKJA 5H8WA 2E9FA 1HY1A 2PTSA 2QGAB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O78 A;  1KQ7 A;  2QVE A;  1HY0 A;  1YFE A;  1B8F A;  3NZ4 A;  1YFM A;  4HGV A;  4V2R A;  2PTQ A;  3R6Q A;  1Q5N A;  2O7B A;  1I0A A;  2VD6 A;  4APB A;  4FLC A;  2O7D A;  4C5S A;  4C5R A;  2HVG A;  3R6Y A;  3RRP A;  2J91 A;  3BHG A;  1EB4 A;  1AUW A;  1C3U A;  4C5U A;  1FUQ A;  1K7W A;  2O6Y A;  1Y2M A;  4CQ5 A;  1YIS A;  2X75 A;  3GZH A;  1JSW A;  1XWO A;  3GTD A;  1VDK A;  2PTR A;  2RJS A;  2OHY A;  3UNV A;  1TJW A;  3TV2 A;  1TJV A;  1DCN A;  4MX2 A;  3KDY A;  4BAA A;  2NYN A;  4BAB A;  2NYF A;  4V2Q A;  3R6V A;  2FUS A;  4NSL A;  3QBP A;  4C6G A;  1C3C A;  2YII A;  4EFC A;  2PTS A;  1U15 A;  1U16 A;  3KDZ A;  3CZO A;  1K62 A;  3C8T A;  1GK3 A;  3NO9 A;  1TJU A;  5D6B A;  5F92 A;  3OCF A;  2RJR A;  5F91 A;  1DOF A;  1J3U A;  4NLE A;  1FUR A;  4FFX A;  1RE5 A;  3OCE A;  5EYV A;  4APA A;  5HW2 A;  4ADL A;  1T6P A;  5EYT A;  1FUO A;  4EEI A;  2O7F A;  1W27 A;  3RD8 A;  1T6J A;  4ADM A;  2O7E A;  3E04 A;  2PFM A;  1GKM A;  1FUP A;  1TJ7 A;  1GKJ A;  2E9F A;  1HY1 A;  1GK2 A;  2QGA B; 
#chains in the Genus database with same CATH topology
 1Z4I A;  2O78 A;  4YIH A;  1KQ7 A;  2QVE A;  1HY0 A;  1YFE A;  1GK2 A;  1B8F A;  3NZ4 A;  1YFM A;  4HGV A;  1MH9 A;  1U0L A;  4V2R A;  2PTQ A;  1XMD A;  3R6Q A;  3F4R A;  2VL7 A;  4L57 A;  1Q5N A;  2O7B A;  1I0A A;  2VD6 A;  2FEL A;  4APB A;  4FLC A;  2O7D A;  4C5S A;  4C5R A;  2HVG A;  3R6Y A;  3RRP A;  1Z4P X;  2J91 A;  3BHG A;  1AUW A;  1EB4 A;  1C3U A;  4C5U A;  3CRW 1;  1FUQ A;  1K7W A;  2O6Y A;  2JAO A;  1XMC A;  2I7D A;  1IW7 D;  1Y2M A;  4CQ5 A;  1YIS A;  2X75 A;  3GZH A;  1Z4K A;  1JSW A;  1XWO A;  3CI0 K;  4L6A A;  4E88 A;  3GTD A;  1VDK A;  2PTR A;  2RJS A;  2RCN A;  2OHY A;  3UNV A;  1TJW A;  4MWO A;  3TV2 A;  1TJV A;  1DCN A;  4MX2 A;  1Q91 A;  3KDY A;  3U13 A;  4BAA A;  2NYN A;  4BAB A;  1Z4Q A;  2NYF A;  4V2Q A;  2D28 C;  3R6V A;  3U19 A;  2FUS A;  2JAW A;  3QBP A;  4NSL A;  3F4S A;  1Z4L A;  3BWV A;  4A15 A;  4C6G A;  1C3C A;  2YII A;  2JAU A;  4EFC A;  1U15 A;  1U16 A;  3KDZ A;  3CZO A;  1K62 A;  3C8T A;  1GK3 A;  5M0I A;  3NO9 A;  1TJU A;  5D6B A;  5F92 A;  3OCF A;  2RJR A;  5F91 A;  1Z4J A;  1DOF A;  1J3U A;  4NLE A;  1FUR A;  4FFX A;  1RE5 A;  4WNL A;  3OCE A;  3F4T A;  4MUM A;  1Q92 A;  5EYV A;  4APA A;  1XL7 A;  4L6C A;  5HW2 A;  4ADL A;  1Z4M A;  1T6P A;  4IQJ M;  2FEN A;  5EYT A;  4NFL A;  1FUO A;  1XLY A;  4EEI A;  2O7F A;  2JAR A;  1XL8 A;  4YIK A;  2VSF A;  2YV5 A;  1T9H A;  2D27 A;  1W27 A;  3RD8 A;  1T6J A;  4ADM A;  2O7E A;  3E04 A;  3CRV A;  2PFM A;  1GKM A;  1FUP A;  1TJ7 A;  5M0J A;  1GKJ A;  5H8W A;  2E9F A;  1HY1 A;  2PTS A;  2QGA B; 
#chains in the Genus database with same CATH homology
 2O78 A;  1KQ7 A;  2QVE A;  1HY0 A;  1YFE A;  1GK2 A;  1B8F A;  3NZ4 A;  1YFM A;  4HGV A;  4V2R A;  2PTQ A;  1XMD A;  3R6Q A;  2VL7 A;  1Q5N A;  2O7B A;  1I0A A;  2VD6 A;  4APB A;  4FLC A;  2O7D A;  4C5S A;  4C5R A;  2HVG A;  3R6Y A;  3RRP A;  2J91 A;  3BHG A;  1AUW A;  1EB4 A;  1C3U A;  4C5U A;  3CRW 1;  1FUQ A;  1K7W A;  2O6Y A;  1XMC A;  1Y2M A;  4CQ5 A;  1YIS A;  2X75 A;  3GZH A;  1JSW A;  1XWO A;  3GTD A;  1VDK A;  2PTR A;  2RJS A;  2OHY A;  3UNV A;  1TJW A;  3TV2 A;  1TJV A;  1DCN A;  4MX2 A;  3KDY A;  4BAA A;  2NYN A;  4BAB A;  2NYF A;  4V2Q A;  3R6V A;  2FUS A;  4NSL A;  3QBP A;  4A15 A;  4C6G A;  1C3C A;  2YII A;  4EFC A;  1U15 A;  1U16 A;  3KDZ A;  3CZO A;  1K62 A;  3C8T A;  1GK3 A;  3NO9 A;  1TJU A;  5D6B A;  5F92 A;  3OCF A;  2RJR A;  5F91 A;  1DOF A;  1J3U A;  4NLE A;  1FUR A;  4FFX A;  1RE5 A;  3OCE A;  5EYV A;  1XL7 A;  4APA A;  5HW2 A;  4ADL A;  1T6P A;  5EYT A;  1FUO A;  4EEI A;  2O7F A;  1XL8 A;  2VSF A;  1W27 A;  3RD8 A;  1T6J A;  4ADM A;  2O7E A;  3E04 A;  3CRV A;  2PFM A;  1GKM A;  1FUP A;  1TJ7 A;  1GKJ A;  5H8W A;  2E9F A;  1HY1 A;  2PTS A;  2QGA B; 
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