2E9FA

Crystal structure of t.th.hb8 argininosuccinate lyase complexed with l-arginine
Total Genus 168
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
449
structure length
449
Chain Sequence
PDALAARFNASLAFDRALWREDLWQNRVHARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFPWREELEDVHMNLEARLTELVGPPGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHFTARELGFKAPMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEELILYSTEEFGFVEVPDAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGLPLAYNKDLQEDKEPLLDALATYRDSLRLLAALLPGLKWRRERMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEEGRALKDLTLEELQAHHPLFAEDALPLLRLETAIHRRRSYGGTAPEAVRERLEEAKKEVGLD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine
rcsb
source organism Thermus thermophilus
molecule tags Lyase
molecule keywords Argininosuccinate lyase
total genus 168
structure length 449
sequence length 449
chains with identical sequence B, C, D
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2007-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2e9fA03
1.10.275.50 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase C; Chain B, domain 1 2e9fA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2e9fA02
2NYNA 3RRPA 3TV2A 1T6PA 1K7WA 2NYFA 3NZ4A 4HGVA 1FUPA 1YFEA 1HY0A 1AUWA 4NSLA 2PTSA 1DOFA 5EYVA 4C5SA 1J3UA 3E04A 4ADMA 2O6YA 1C3CA 4V2QA 2J91A 1T6JA 5F91A 1GK3A 4APAA 4EEIA 1VDKA 1FUOA 3QBPA 2PTQA 5D6BA 3KDZA 1K62A 4CQ5A 4C6GA 2O78A 3GZHA 4NLEA 3KDYA 3BHGA 4ADLA 1Q5NA 2RJRA 1JSWA 1EB4A 4C5RA 1XWOA 2OHYA 2VD6A 3OCFA 2O7DA 1W27A 2O7FA 3UNVA 2PTRA 4EFCA 1YISA 4C5UA 4V2RA 5EYTA 1I0AA 1U16A 3OCEA 3NO9A 2E9FA 3R6YA 1TJVA 2RJSA 1HY1A 3R6QA 1U15A 2O7BA 1TJWA 1KQ7A 5HW2A 1GKMA 2QGAB 2HVGA 1DCNA 2QVEA 1RE5A 3R6VA 3CZOA 3GTDA 1GK2A 1Y2MA 4APBA 4BABA 1FURA 1TJ7A 3RD8A 1B8FA 1GKJA 2X75A 2O7EA 2PFMA 2YIIA 4FLCA 3C8TA 5F92A 4MX2A 1YFMA 1FUQA 4BAAA 1TJUA 4FFXA 2FUSA 1C3UA
chains in the Genus database with same CATH superfamily
1Z4MA 2NYNA 3RRPA 3TV2A 1T6PA 2JAWA 1Q92A 2RCNA 1K7WA 2NYFA 3NZ4A 4HGVA 1Z4LA 1FUPA 1YFEA 1HY0A 1Z4QA 1AUWA 1Z4KA 4NSLA 3F4SA 2PTSA 2VL7A 1DOFA 5EYVA 4C5SA 1J3UA 3E04A 4ADMA 2O6YA 2FELA 1C3CA 3F4TA 1XL8A 2J91A 1T6JA 5F91A 1XL7A 1GK3A 4V2QA 4APAA 4EEIA 1VDKA 3CI0K 1XLYA 1FUOA 3QBPA 3F4RA 1XMDA 2PTQA 3BWVA 5D6BA 4YIHA 3KDZA 1K62A 4CQ5A 4C6GA 5H8WA 2O78A 5M0JA 3GZHA 4NLEA 3KDYA 3BHGA 4ADLA 1Q5NA 2RJRA 4E88A 1XMCA 4MWOA 1JSWA 1EB4A 5M0IA 4C5RA 1XWOA 2JAOA 2OHYA 1Z4JA 2VD6A 3OCFA 2I7DA 1Z4PX 2O7DA 4NFLA 1U0LA 1W27A 2O7FA 3CRVA 3UNVA 2PTRA 4EFCA 1YISA 4C5UA 4V2RA 5EYTA 2JAUA 1T9HA 1I0AA 1Q91A 1U16A 3U13A 3OCEA 3NO9A 2E9FA 3R6YA 2D28C 1TJVA 2RJSA 1HY1A 3R6QA 1IW7D 4L6AA 4YIKA 1U15A 2O7BA 1TJWA 1KQ7A 1Z4IA 5HW2A 1GKMA 4WNLA 4MUMA 2QGAB 2HVGA 1DCNA 2QVEA 1RE5A 3R6VA 3U19A 3CZOA 3GTDA 1GK2A 1Y2MA 4L6CA 4APBA 4BABA 2D27A 1FURA 1TJ7A 3RD8A 1B8FA 1GKJA 2X75A 2O7EA 2YV5A 2PFMA 2YIIA 4FLCA 4A15A 3C8TA 3CRW1 5F92A 4MX2A 1MH9A 1YFMA 4IQJM 2VSFA 2JARA 2FENA 1FUQA 4L57A 4BAAA 1TJUA 4FFXA 2FUSA 1C3UA
chains in the Genus database with same CATH topology
2NYNA 3RRPA 3TV2A 1T6PA 1K7WA 2NYFA 3NZ4A 4HGVA 1FUPA 1YFEA 1HY0A 1AUWA 4NSLA 2PTSA 2VL7A 1DOFA 5EYVA 4C5SA 1J3UA 3E04A 4ADMA 2O6YA 1C3CA 4V2QA 1XL8A 2J91A 1T6JA 5F91A 1XL7A 1GK3A 4APAA 4EEIA 1VDKA 1FUOA 3QBPA 1XMDA 2PTQA 5D6BA 3KDZA 1K62A 4CQ5A 4C6GA 5H8WA 2O78A 3GZHA 4NLEA 3KDYA 3BHGA 4ADLA 1Q5NA 2RJRA 1XMCA 1JSWA 1EB4A 4C5RA 1XWOA 2OHYA 2VD6A 3OCFA 2O7DA 1W27A 2O7FA 3CRVA 3UNVA 2PTRA 4EFCA 1YISA 4C5UA 4V2RA 5EYTA 1I0AA 1U16A 3OCEA 3NO9A 2E9FA 3R6YA 1TJVA 2RJSA 1HY1A 3R6QA 1U15A 2O7BA 1TJWA 1KQ7A 5HW2A 1GKMA 2QGAB 2HVGA 1DCNA 2QVEA 1RE5A 3R6VA 3CZOA 3GTDA 1GK2A 1Y2MA 4APBA 4BABA 1FURA 1TJ7A 3RD8A 1B8FA 1GKJA 2X75A 2O7EA 2PFMA 2YIIA 4FLCA 4A15A 3C8TA 3CRW1 5F92A 4MX2A 1YFMA 2VSFA 1FUQA 4BAAA 1TJUA 4FFXA 2FUSA 1C3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYN A;  3RRP A;  3TV2 A;  1T6P A;  1K7W A;  2NYF A;  3NZ4 A;  4HGV A;  1FUP A;  1YFE A;  1HY0 A;  1AUW A;  4NSL A;  2PTS A;  1DOF A;  5EYV A;  4C5S A;  1J3U A;  3E04 A;  4ADM A;  2O6Y A;  1C3C A;  4V2Q A;  2J91 A;  1T6J A;  5F91 A;  1GK3 A;  4APA A;  4EEI A;  1VDK A;  1FUO A;  3QBP A;  2PTQ A;  5D6B A;  3KDZ A;  1K62 A;  4CQ5 A;  4C6G A;  2O78 A;  3GZH A;  4NLE A;  3KDY A;  3BHG A;  4ADL A;  1Q5N A;  2RJR A;  1JSW A;  1EB4 A;  4C5R A;  1XWO A;  2OHY A;  2VD6 A;  3OCF A;  2O7D A;  1W27 A;  2O7F A;  3UNV A;  2PTR A;  4EFC A;  1YIS A;  4C5U A;  4V2R A;  5EYT A;  1I0A A;  1U16 A;  3OCE A;  3NO9 A;  2E9F A;  3R6Y A;  1TJV A;  2RJS A;  1HY1 A;  3R6Q A;  1U15 A;  2O7B A;  1TJW A;  1KQ7 A;  5HW2 A;  1GKM A;  2QGA B;  2HVG A;  1DCN A;  2QVE A;  1RE5 A;  3R6V A;  3CZO A;  3GTD A;  1GK2 A;  1Y2M A;  4APB A;  4BAB A;  1FUR A;  1TJ7 A;  3RD8 A;  1B8F A;  1GKJ A;  2X75 A;  2O7E A;  2PFM A;  2YII A;  4FLC A;  3C8T A;  5F92 A;  4MX2 A;  1YFM A;  1FUQ A;  4BAA A;  1TJU A;  4FFX A;  2FUS A;  1C3U A; 
#chains in the Genus database with same CATH topology
 1Z4M A;  2NYN A;  3RRP A;  3TV2 A;  1T6P A;  2JAW A;  1Q92 A;  2RCN A;  1K7W A;  2NYF A;  3NZ4 A;  4HGV A;  1Z4L A;  1FUP A;  1YFE A;  1HY0 A;  1Z4Q A;  1AUW A;  1Z4K A;  4NSL A;  3F4S A;  2PTS A;  2VL7 A;  1DOF A;  5EYV A;  4C5S A;  1J3U A;  3E04 A;  4ADM A;  2O6Y A;  2FEL A;  1C3C A;  3F4T A;  1XL8 A;  2J91 A;  1T6J A;  5F91 A;  1XL7 A;  1GK3 A;  4V2Q A;  4APA A;  4EEI A;  1VDK A;  3CI0 K;  1XLY A;  1FUO A;  3QBP A;  3F4R A;  1XMD A;  2PTQ A;  3BWV A;  5D6B A;  4YIH A;  3KDZ A;  1K62 A;  4CQ5 A;  4C6G A;  5H8W A;  2O78 A;  5M0J A;  3GZH A;  4NLE A;  3KDY A;  3BHG A;  4ADL A;  1Q5N A;  2RJR A;  4E88 A;  1XMC A;  4MWO A;  1JSW A;  1EB4 A;  5M0I A;  4C5R A;  1XWO A;  2JAO A;  2OHY A;  1Z4J A;  2VD6 A;  3OCF A;  2I7D A;  1Z4P X;  2O7D A;  4NFL A;  1U0L A;  1W27 A;  2O7F A;  3CRV A;  3UNV A;  2PTR A;  4EFC A;  1YIS A;  4C5U A;  4V2R A;  5EYT A;  2JAU A;  1T9H A;  1I0A A;  1Q91 A;  1U16 A;  3U13 A;  3OCE A;  3NO9 A;  2E9F A;  3R6Y A;  2D28 C;  1TJV A;  2RJS A;  1HY1 A;  3R6Q A;  1IW7 D;  4L6A A;  4YIK A;  1U15 A;  2O7B A;  1TJW A;  1KQ7 A;  1Z4I A;  5HW2 A;  1GKM A;  4WNL A;  4MUM A;  2QGA B;  2HVG A;  1DCN A;  2QVE A;  1RE5 A;  3R6V A;  3U19 A;  3CZO A;  3GTD A;  1GK2 A;  1Y2M A;  4L6C A;  4APB A;  4BAB A;  2D27 A;  1FUR A;  1TJ7 A;  3RD8 A;  1B8F A;  1GKJ A;  2X75 A;  2O7E A;  2YV5 A;  2PFM A;  2YII A;  4FLC A;  4A15 A;  3C8T A;  3CRW 1;  5F92 A;  4MX2 A;  1MH9 A;  1YFM A;  4IQJ M;  2VSF A;  2JAR A;  2FEN A;  1FUQ A;  4L57 A;  4BAA A;  1TJU A;  4FFX A;  2FUS A;  1C3U A; 
#chains in the Genus database with same CATH homology
 2NYN A;  3RRP A;  3TV2 A;  1T6P A;  1K7W A;  2NYF A;  3NZ4 A;  4HGV A;  1FUP A;  1YFE A;  1HY0 A;  1AUW A;  4NSL A;  2PTS A;  2VL7 A;  1DOF A;  5EYV A;  4C5S A;  1J3U A;  3E04 A;  4ADM A;  2O6Y A;  1C3C A;  4V2Q A;  1XL8 A;  2J91 A;  1T6J A;  5F91 A;  1XL7 A;  1GK3 A;  4APA A;  4EEI A;  1VDK A;  1FUO A;  3QBP A;  1XMD A;  2PTQ A;  5D6B A;  3KDZ A;  1K62 A;  4CQ5 A;  4C6G A;  5H8W A;  2O78 A;  3GZH A;  4NLE A;  3KDY A;  3BHG A;  4ADL A;  1Q5N A;  2RJR A;  1XMC A;  1JSW A;  1EB4 A;  4C5R A;  1XWO A;  2OHY A;  2VD6 A;  3OCF A;  2O7D A;  1W27 A;  2O7F A;  3CRV A;  3UNV A;  2PTR A;  4EFC A;  1YIS A;  4C5U A;  4V2R A;  5EYT A;  1I0A A;  1U16 A;  3OCE A;  3NO9 A;  2E9F A;  3R6Y A;  1TJV A;  2RJS A;  1HY1 A;  3R6Q A;  1U15 A;  2O7B A;  1TJW A;  1KQ7 A;  5HW2 A;  1GKM A;  2QGA B;  2HVG A;  1DCN A;  2QVE A;  1RE5 A;  3R6V A;  3CZO A;  3GTD A;  1GK2 A;  1Y2M A;  4APB A;  4BAB A;  1FUR A;  1TJ7 A;  3RD8 A;  1B8F A;  1GKJ A;  2X75 A;  2O7E A;  2PFM A;  2YII A;  4FLC A;  4A15 A;  3C8T A;  3CRW 1;  5F92 A;  4MX2 A;  1YFM A;  2VSF A;  1FUQ A;  4BAA A;  1TJU A;  4FFX A;  2FUS A;  1C3U A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...