2E9FA

Crystal structure of t.th.hb8 argininosuccinate lyase complexed with l-arginine
Total Genus 168
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
449
structure length
449
Chain Sequence
PDALAARFNASLAFDRALWREDLWQNRVHARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFPWREELEDVHMNLEARLTELVGPPGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHFTARELGFKAPMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEELILYSTEEFGFVEVPDAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGLPLAYNKDLQEDKEPLLDALATYRDSLRLLAALLPGLKWRRERMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEEGRALKDLTLEELQAHHPLFAEDALPLLRLETAIHRRRSYGGTAPEAVRERLEEAKKEVGLD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine
rcsb
source organism Thermus thermophilus
molecule tags Lyase
molecule keywords Argininosuccinate lyase
total genus 168
structure length 449
sequence length 449
chains with identical sequence B, C, D
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2007-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2e9fA03
1.10.275.50 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase C; Chain B, domain 1 2e9fA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2e9fA02
2O7EA 3R6VA 2PTRA 4FFXA 4MX2A 2O78A 1Q5NA 3OCFA 1RE5A 1GKMA 3KDYA 5D6BA 4ADMA 1Y2MA 3BHGA 1W27A 3CZOA 1K62A 3C8TA 1KQ7A 1EB4A 2FUSA 4APAA 4NSLA 4APBA 4BABA 2E9FA 1K7WA 3TV2A 4ADLA 4C5RA 1GK2A 2PTQA 2QGAB 3QBPA 2RJSA 4BAAA 1U16A 1TJVA 1GK3A 1TJ7A 2YIIA 4C5SA 2X75A 4EEIA 4C5UA 1T6JA 1TJUA 3E04A 1VDKA 2NYFA 1HY1A 2O6YA 3KDZA 3NZ4A 4V2QA 1TJWA 1J3UA 1B8FA 1FUQA 1GKJA 5F92A 1DCNA 2J91A 2NYNA 2PTSA 1U15A 1DOFA 1XWOA 1YFMA 1I0AA 2PFMA 4C6GA 4V2RA 5EYVA 2O7DA 3GTDA 2RJRA 1JSWA 1YFEA 3RD8A 4EFCA 2VD6A 1FUOA 4CQ5A 2O7BA 2OHYA 5F91A 5EYTA 5HW2A 2HVGA 4NLEA 1C3CA 1AUWA 2O7FA 3OCEA 1YISA 3R6YA 3RRPA 3NO9A 4FLCA 3GZHA 1FURA 4HGVA 1C3UA 3R6QA 1T6PA 1HY0A 2QVEA 1FUPA 3UNVA
chains in the Genus database with same CATH superfamily
2O7EA 3R6VA 2PTRA 4FFXA 4MX2A 2O78A 1Q5NA 3OCFA 1XL7A 1RE5A 1GKMA 3KDYA 5D6BA 4ADMA 1Y2MA 3BHGA 4L57A 1W27A 3CZOA 1K62A 3C8TA 1KQ7A 1T9HA 1EB4A 2FUSA 4APAA 4NSLA 4APBA 4BABA 2E9FA 4YIHA 2I7DA 1K7WA 1XL8A 5M0JA 3TV2A 4ADLA 4C5RA 1IW7D 1GK2A 3U13A 2PTQA 2D28C 2QGAB 3QBPA 3UNVA 2RJSA 4BAAA 1U16A 1TJVA 4L6AA 1TJ7A 1GK3A 2YIIA 4C5SA 2X75A 3F4RA 4EEIA 2FELA 4C5UA 3CRW1 4A15A 1T6JA 1TJUA 3E04A 1VDKA 2NYFA 1HY1A 1Z4MA 2YV5A 2O6YA 3KDZA 3NZ4A 4V2QA 1TJWA 3BWVA 2VSFA 1J3UA 1B8FA 2FENA 2RCNA 1Q91A 4YIKA 4NFLA 1FUQA 3F4TA 3CI0K 1GKJA 3F4SA 5F92A 1Z4PX 1DCNA 2J91A 2NYNA 1XMCA 2PTSA 1U15A 1DOFA 1Z4JA 1U0LA 1XWOA 1YFMA 2JAOA 1I0AA 1XLYA 2PFMA 4C6GA 2JARA 4V2RA 5EYVA 1Q92A 3GTDA 2O7DA 1Z4IA 2RJRA 1JSWA 1YFEA 3RD8A 4EFCA 2VD6A 1FUOA 4CQ5A 2O7BA 2OHYA 5F91A 2VL7A 5EYTA 5M0IA 1Z4LA 5H8WA 3CRVA 5HW2A 2HVGA 4NLEA 4E88A 3U19A 1C3CA 1AUWA 2O7FA 1Z4KA 2D27A 3OCEA 1YISA 3R6YA 3RRPA 3NO9A 4IQJM 4MWOA 1Z4QA 4FLCA 4WNLA 3GZHA 4L6CA 1FURA 4HGVA 1C3UA 3R6QA 1T6PA 1HY0A 4MUMA 1XMDA 2JAUA 2QVEA 1FUPA 2JAWA 1MH9A
chains in the Genus database with same CATH topology
2O7EA 3R6VA 2PTRA 4FFXA 4MX2A 2O78A 1Q5NA 3OCFA 1XL7A 1RE5A 1GKMA 3KDYA 5D6BA 4ADMA 1Y2MA 3BHGA 1W27A 3CZOA 1K62A 3C8TA 1KQ7A 1EB4A 2FUSA 4APAA 4NSLA 4APBA 4BABA 2E9FA 1XL8A 1K7WA 3TV2A 4ADLA 4C5RA 1GK2A 2PTQA 2QGAB 3QBPA 2RJSA 4BAAA 1U16A 1TJVA 1GK3A 1TJ7A 2YIIA 4C5SA 2X75A 4EEIA 4C5UA 3CRW1 4A15A 1T6JA 1TJUA 3E04A 1VDKA 2NYFA 1HY1A 2O6YA 3KDZA 3NZ4A 4V2QA 1TJWA 2VSFA 1J3UA 1B8FA 1FUQA 1GKJA 5F92A 1DCNA 2J91A 2NYNA 1XMCA 2PTSA 1U15A 1DOFA 1XWOA 1YFMA 1I0AA 2PFMA 4C6GA 4V2RA 5EYVA 2O7DA 3GTDA 2RJRA 1JSWA 1YFEA 3RD8A 4EFCA 2VD6A 1FUOA 4CQ5A 2O7BA 2OHYA 5F91A 2VL7A 5EYTA 5H8WA 3CRVA 5HW2A 2HVGA 4NLEA 1C3CA 1AUWA 2O7FA 3OCEA 1YISA 3R6YA 3RRPA 3NO9A 4FLCA 3GZHA 1FURA 4HGVA 1C3UA 3R6QA 1T6PA 1HY0A 1XMDA 2QVEA 1FUPA 3UNVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O7E A;  3R6V A;  2PTR A;  4FFX A;  4MX2 A;  2O78 A;  1Q5N A;  3OCF A;  1RE5 A;  1GKM A;  3KDY A;  5D6B A;  4ADM A;  1Y2M A;  3BHG A;  1W27 A;  3CZO A;  1K62 A;  3C8T A;  1KQ7 A;  1EB4 A;  2FUS A;  4APA A;  4NSL A;  4APB A;  4BAB A;  2E9F A;  1K7W A;  3TV2 A;  4ADL A;  4C5R A;  1GK2 A;  2PTQ A;  2QGA B;  3QBP A;  2RJS A;  4BAA A;  1U16 A;  1TJV A;  1GK3 A;  1TJ7 A;  2YII A;  4C5S A;  2X75 A;  4EEI A;  4C5U A;  1T6J A;  1TJU A;  3E04 A;  1VDK A;  2NYF A;  1HY1 A;  2O6Y A;  3KDZ A;  3NZ4 A;  4V2Q A;  1TJW A;  1J3U A;  1B8F A;  1FUQ A;  1GKJ A;  5F92 A;  1DCN A;  2J91 A;  2NYN A;  2PTS A;  1U15 A;  1DOF A;  1XWO A;  1YFM A;  1I0A A;  2PFM A;  4C6G A;  4V2R A;  5EYV A;  2O7D A;  3GTD A;  2RJR A;  1JSW A;  1YFE A;  3RD8 A;  4EFC A;  2VD6 A;  1FUO A;  4CQ5 A;  2O7B A;  2OHY A;  5F91 A;  5EYT A;  5HW2 A;  2HVG A;  4NLE A;  1C3C A;  1AUW A;  2O7F A;  3OCE A;  1YIS A;  3R6Y A;  3RRP A;  3NO9 A;  4FLC A;  3GZH A;  1FUR A;  4HGV A;  1C3U A;  3R6Q A;  1T6P A;  1HY0 A;  2QVE A;  1FUP A;  3UNV A; 
#chains in the Genus database with same CATH topology
 2O7E A;  3R6V A;  2PTR A;  4FFX A;  4MX2 A;  2O78 A;  1Q5N A;  3OCF A;  1XL7 A;  1RE5 A;  1GKM A;  3KDY A;  5D6B A;  4ADM A;  1Y2M A;  3BHG A;  4L57 A;  1W27 A;  3CZO A;  1K62 A;  3C8T A;  1KQ7 A;  1T9H A;  1EB4 A;  2FUS A;  4APA A;  4NSL A;  4APB A;  4BAB A;  2E9F A;  4YIH A;  2I7D A;  1K7W A;  1XL8 A;  5M0J A;  3TV2 A;  4ADL A;  4C5R A;  1IW7 D;  1GK2 A;  3U13 A;  2PTQ A;  2D28 C;  2QGA B;  3QBP A;  3UNV A;  2RJS A;  4BAA A;  1U16 A;  1TJV A;  4L6A A;  1TJ7 A;  1GK3 A;  2YII A;  4C5S A;  2X75 A;  3F4R A;  4EEI A;  2FEL A;  4C5U A;  3CRW 1;  4A15 A;  1T6J A;  1TJU A;  3E04 A;  1VDK A;  2NYF A;  1HY1 A;  1Z4M A;  2YV5 A;  2O6Y A;  3KDZ A;  3NZ4 A;  4V2Q A;  1TJW A;  3BWV A;  2VSF A;  1J3U A;  1B8F A;  2FEN A;  2RCN A;  1Q91 A;  4YIK A;  4NFL A;  1FUQ A;  3F4T A;  3CI0 K;  1GKJ A;  3F4S A;  5F92 A;  1Z4P X;  1DCN A;  2J91 A;  2NYN A;  1XMC A;  2PTS A;  1U15 A;  1DOF A;  1Z4J A;  1U0L A;  1XWO A;  1YFM A;  2JAO A;  1I0A A;  1XLY A;  2PFM A;  4C6G A;  2JAR A;  4V2R A;  5EYV A;  1Q92 A;  3GTD A;  2O7D A;  1Z4I A;  2RJR A;  1JSW A;  1YFE A;  3RD8 A;  4EFC A;  2VD6 A;  1FUO A;  4CQ5 A;  2O7B A;  2OHY A;  5F91 A;  2VL7 A;  5EYT A;  5M0I A;  1Z4L A;  5H8W A;  3CRV A;  5HW2 A;  2HVG A;  4NLE A;  4E88 A;  3U19 A;  1C3C A;  1AUW A;  2O7F A;  1Z4K A;  2D27 A;  3OCE A;  1YIS A;  3R6Y A;  3RRP A;  3NO9 A;  4IQJ M;  4MWO A;  1Z4Q A;  4FLC A;  4WNL A;  3GZH A;  4L6C A;  1FUR A;  4HGV A;  1C3U A;  3R6Q A;  1T6P A;  1HY0 A;  4MUM A;  1XMD A;  2JAU A;  2QVE A;  1FUP A;  2JAW A;  1MH9 A; 
#chains in the Genus database with same CATH homology
 2O7E A;  3R6V A;  2PTR A;  4FFX A;  4MX2 A;  2O78 A;  1Q5N A;  3OCF A;  1XL7 A;  1RE5 A;  1GKM A;  3KDY A;  5D6B A;  4ADM A;  1Y2M A;  3BHG A;  1W27 A;  3CZO A;  1K62 A;  3C8T A;  1KQ7 A;  1EB4 A;  2FUS A;  4APA A;  4NSL A;  4APB A;  4BAB A;  2E9F A;  1XL8 A;  1K7W A;  3TV2 A;  4ADL A;  4C5R A;  1GK2 A;  2PTQ A;  2QGA B;  3QBP A;  2RJS A;  4BAA A;  1U16 A;  1TJV A;  1GK3 A;  1TJ7 A;  2YII A;  4C5S A;  2X75 A;  4EEI A;  4C5U A;  3CRW 1;  4A15 A;  1T6J A;  1TJU A;  3E04 A;  1VDK A;  2NYF A;  1HY1 A;  2O6Y A;  3KDZ A;  3NZ4 A;  4V2Q A;  1TJW A;  2VSF A;  1J3U A;  1B8F A;  1FUQ A;  1GKJ A;  5F92 A;  1DCN A;  2J91 A;  2NYN A;  1XMC A;  2PTS A;  1U15 A;  1DOF A;  1XWO A;  1YFM A;  1I0A A;  2PFM A;  4C6G A;  4V2R A;  5EYV A;  2O7D A;  3GTD A;  2RJR A;  1JSW A;  1YFE A;  3RD8 A;  4EFC A;  2VD6 A;  1FUO A;  4CQ5 A;  2O7B A;  2OHY A;  5F91 A;  2VL7 A;  5EYT A;  5H8W A;  3CRV A;  5HW2 A;  2HVG A;  4NLE A;  1C3C A;  1AUW A;  2O7F A;  3OCE A;  1YIS A;  3R6Y A;  3RRP A;  3NO9 A;  4FLC A;  3GZH A;  1FUR A;  4HGV A;  1C3U A;  3R6Q A;  1T6P A;  1HY0 A;  1XMD A;  2QVE A;  1FUP A;  3UNV A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...