2E9FA

Crystal structure of t.th.hb8 argininosuccinate lyase complexed with l-arginine
Total Genus 168
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
449
structure length
449
Chain Sequence
b'PDALAARFNASLAFDRALWREDLWQNRVHARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFPWREELEDVHMNLEARLTELVGPPGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHFTARELGFKAPMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEELILYSTEEFGFVEVPDAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGLPLAYNKDLQEDKEPLLDALATYRDSLRLLAALLPGLKWRRERMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEEGRALKDLTLEELQAHHPLFAEDALPLLRLETAIHRRRSYGGTAPEAVRERLEEAKKEVGLD'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Argininosuccinate lyase
publication title Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine
rcsb
source organism Thermus thermophilus
molecule tags Lyase
total genus 168
structure length 449
sequence length 449
chains with identical sequence B, C, D
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2007-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2e9fA03
1.10.275.50 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase C; Chain B, domain 1 2e9fA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2e9fA02
5F91A 2O7EA 2PTSA 4FFXA 1GKMA 2NYNA 4APAA 3NO9A 1DOFA 3E04A 1TJUA 1YFMA 1U15A 2PFMA 3NZ4A 1U16A 1K7WA 4NSLA 2X75A 1TJ7A 3QBPA 1C3UA 1W27A 4C5RA 1RE5A 1TJWA 1GK3A 2O78A 1KQ7A 4ADMA 1VDKA 2O7BA 4C5UA 1TJVA 1T6PA 1JSWA 4APBA 4V2RA 3OCFA 2QGAB 1J3UA 2O7FA 4NLEA 2PTQA 4FLCA 5EYVA 2HVGA 3KDZA 2PTRA 4BABA 2E9FA 1HY0A 1GKJA 2OHYA 3R6VA 4EFCA 2RJSA 1Q5NA 1FURA 1T6JA 5HW2A 1XWOA 2O7DA 1Y2MA 4BAAA 4C6GA 4V2QA 2QVEA 2FUSA 1B8FA 3KDYA 1HY1A 4ADLA 3RD8A 2NYFA 3R6QA 1FUPA 3OCEA 1AUWA 1C3CA 3TV2A 3R6YA 2J91A 4MX2A 1YISA 4C5SA 5EYTA 1K62A 3CZOA 3GTDA 4CQ5A 1FUOA 5D6BA 1I0AA 3RRPA 2VD6A 3GZHA 1YFEA 2YIIA 4EEIA 1DCNA 1FUQA 3UNVA 1EB4A 3BHGA 2RJRA 1GK2A 2O6YA 4HGVA 5F92A 3C8TA
chains in the Genus database with same CATH superfamily
1XMCA 5F91A 1Z4IA 1XL8A 2PTSA 2O7EA 4FFXA 1Z4QA 1GKMA 2NYNA 4APAA 3NO9A 4MUMA 1DOFA 3E04A 1TJUA 1YFMA 2JAOA 1U15A 2PFMA 3NZ4A 1U16A 1K7WA 4A15A 3U19A 1XL7A 4E88A 4NSLA 2X75A 4L6AA 2JAWA 1TJ7A 4YIHA 3QBPA 1C3UA 1MH9A 1W27A 4C5RA 1RE5A 1TJWA 3F4TA 1GK3A 1KQ7A 2O78A 1Q91A 4ADMA 4MWOA 1VDKA 2O7BA 4C5UA 1TJVA 1T6PA 1JSWA 4APBA 4V2RA 3OCFA 2D28C 2FELA 2QGAB 1J3UA 2O7FA 1XLYA 4NLEA 2PTQA 4FLCA 5EYVA 2HVGA 3KDZA 4YIKA 2PTRA 4BABA 2E9FA 1HY0A 1GKJA 3CI0K 3R6VA 2OHYA 4EFCA 2RJSA 2YV5A 1Q5NA 4IQJM 1XMDA 4WNLA 3U13A 1FURA 1XWOA 5HW2A 1Q92A 1T6JA 2O7DA 1Y2MA 4BAAA 4C6GA 2FENA 1Z4MA 4V2QA 2VSFA 2QVEA 2FUSA 1T9HA 2D27A 1B8FA 3KDYA 1HY1A 4ADLA 3RD8A 1Z4KA 2NYFA 2JAUA 3R6QA 1FUPA 4L57A 3OCEA 3CRVA 1AUWA 1C3CA 3TV2A 3R6YA 2J91A 4MX2A 5M0IA 1YISA 4C5SA 2JARA 5EYTA 1K62A 3CZOA 3GTDA 1IW7D 3F4SA 4CQ5A 1FUOA 5D6BA 1I0AA 3RRPA 3BWVA 2VD6A 4L6CA 3GZHA 1YFEA 5M0JA 2YIIA 3F4RA 1Z4PX 4EEIA 1DCNA 2VL7A 1Z4JA 3CRW1 1FUQA 3UNVA 1U0LA 1EB4A 4NFLA 2I7DA 3BHGA 2RJRA 2RCNA 1GK2A 5H8WA 2O6YA 1Z4LA 4HGVA 5F92A 3C8TA
chains in the Genus database with same CATH topology
1XMCA 5F91A 2O7EA 1XL8A 2PTSA 4FFXA 1GKMA 2NYNA 4APAA 3NO9A 1DOFA 3E04A 1TJUA 1YFMA 1U15A 2PFMA 3NZ4A 1U16A 1K7WA 4A15A 1XL7A 4NSLA 2X75A 1TJ7A 3QBPA 1C3UA 1W27A 4C5RA 1RE5A 1TJWA 1GK3A 2O78A 1KQ7A 4ADMA 1VDKA 2O7BA 4C5UA 1TJVA 1T6PA 1JSWA 4APBA 4V2RA 3OCFA 2QGAB 1J3UA 2O7FA 4NLEA 2PTQA 4FLCA 5EYVA 2HVGA 3KDZA 2PTRA 4BABA 2E9FA 1HY0A 1GKJA 2OHYA 3R6VA 4EFCA 2RJSA 1Q5NA 1XMDA 1FURA 1XWOA 5HW2A 1T6JA 2O7DA 1Y2MA 4BAAA 4C6GA 4V2QA 2VSFA 2QVEA 2FUSA 1B8FA 3KDYA 1HY1A 4ADLA 3RD8A 2NYFA 3R6QA 1FUPA 3OCEA 3CRVA 1AUWA 1C3CA 3TV2A 3R6YA 2J91A 4MX2A 1YISA 4C5SA 5EYTA 1K62A 3CZOA 3GTDA 4CQ5A 1FUOA 5D6BA 1I0AA 3RRPA 2VD6A 3GZHA 1YFEA 2YIIA 4EEIA 1DCNA 2VL7A 3CRW1 1FUQA 3UNVA 1EB4A 3BHGA 2RJRA 1GK2A 5H8WA 2O6YA 4HGVA 5F92A 3C8TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F91 A;  2O7E A;  2PTS A;  4FFX A;  1GKM A;  2NYN A;  4APA A;  3NO9 A;  1DOF A;  3E04 A;  1TJU A;  1YFM A;  1U15 A;  2PFM A;  3NZ4 A;  1U16 A;  1K7W A;  4NSL A;  2X75 A;  1TJ7 A;  3QBP A;  1C3U A;  1W27 A;  4C5R A;  1RE5 A;  1TJW A;  1GK3 A;  2O78 A;  1KQ7 A;  4ADM A;  1VDK A;  2O7B A;  4C5U A;  1TJV A;  1T6P A;  1JSW A;  4APB A;  4V2R A;  3OCF A;  2QGA B;  1J3U A;  2O7F A;  4NLE A;  2PTQ A;  4FLC A;  5EYV A;  2HVG A;  3KDZ A;  2PTR A;  4BAB A;  2E9F A;  1HY0 A;  1GKJ A;  2OHY A;  3R6V A;  4EFC A;  2RJS A;  1Q5N A;  1FUR A;  1T6J A;  5HW2 A;  1XWO A;  2O7D A;  1Y2M A;  4BAA A;  4C6G A;  4V2Q A;  2QVE A;  2FUS A;  1B8F A;  3KDY A;  1HY1 A;  4ADL A;  3RD8 A;  2NYF A;  3R6Q A;  1FUP A;  3OCE A;  1AUW A;  1C3C A;  3TV2 A;  3R6Y A;  2J91 A;  4MX2 A;  1YIS A;  4C5S A;  5EYT A;  1K62 A;  3CZO A;  3GTD A;  4CQ5 A;  1FUO A;  5D6B A;  1I0A A;  3RRP A;  2VD6 A;  3GZH A;  1YFE A;  2YII A;  4EEI A;  1DCN A;  1FUQ A;  3UNV A;  1EB4 A;  3BHG A;  2RJR A;  1GK2 A;  2O6Y A;  4HGV A;  5F92 A;  3C8T A; 
#chains in the Genus database with same CATH topology
 1XMC A;  5F91 A;  1Z4I A;  1XL8 A;  2PTS A;  2O7E A;  4FFX A;  1Z4Q A;  1GKM A;  2NYN A;  4APA A;  3NO9 A;  4MUM A;  1DOF A;  3E04 A;  1TJU A;  1YFM A;  2JAO A;  1U15 A;  2PFM A;  3NZ4 A;  1U16 A;  1K7W A;  4A15 A;  3U19 A;  1XL7 A;  4E88 A;  4NSL A;  2X75 A;  4L6A A;  2JAW A;  1TJ7 A;  4YIH A;  3QBP A;  1C3U A;  1MH9 A;  1W27 A;  4C5R A;  1RE5 A;  1TJW A;  3F4T A;  1GK3 A;  1KQ7 A;  2O78 A;  1Q91 A;  4ADM A;  4MWO A;  1VDK A;  2O7B A;  4C5U A;  1TJV A;  1T6P A;  1JSW A;  4APB A;  4V2R A;  3OCF A;  2D28 C;  2FEL A;  2QGA B;  1J3U A;  2O7F A;  1XLY A;  4NLE A;  2PTQ A;  4FLC A;  5EYV A;  2HVG A;  3KDZ A;  4YIK A;  2PTR A;  4BAB A;  2E9F A;  1HY0 A;  1GKJ A;  3CI0 K;  3R6V A;  2OHY A;  4EFC A;  2RJS A;  2YV5 A;  1Q5N A;  4IQJ M;  1XMD A;  4WNL A;  3U13 A;  1FUR A;  1XWO A;  5HW2 A;  1Q92 A;  1T6J A;  2O7D A;  1Y2M A;  4BAA A;  4C6G A;  2FEN A;  1Z4M A;  4V2Q A;  2VSF A;  2QVE A;  2FUS A;  1T9H A;  2D27 A;  1B8F A;  3KDY A;  1HY1 A;  4ADL A;  3RD8 A;  1Z4K A;  2NYF A;  2JAU A;  3R6Q A;  1FUP A;  4L57 A;  3OCE A;  3CRV A;  1AUW A;  1C3C A;  3TV2 A;  3R6Y A;  2J91 A;  4MX2 A;  5M0I A;  1YIS A;  4C5S A;  2JAR A;  5EYT A;  1K62 A;  3CZO A;  3GTD A;  1IW7 D;  3F4S A;  4CQ5 A;  1FUO A;  5D6B A;  1I0A A;  3RRP A;  3BWV A;  2VD6 A;  4L6C A;  3GZH A;  1YFE A;  5M0J A;  2YII A;  3F4R A;  1Z4P X;  4EEI A;  1DCN A;  2VL7 A;  1Z4J A;  3CRW 1;  1FUQ A;  3UNV A;  1U0L A;  1EB4 A;  4NFL A;  2I7D A;  3BHG A;  2RJR A;  2RCN A;  1GK2 A;  5H8W A;  2O6Y A;  1Z4L A;  4HGV A;  5F92 A;  3C8T A; 
#chains in the Genus database with same CATH homology
 1XMC A;  5F91 A;  2O7E A;  1XL8 A;  2PTS A;  4FFX A;  1GKM A;  2NYN A;  4APA A;  3NO9 A;  1DOF A;  3E04 A;  1TJU A;  1YFM A;  1U15 A;  2PFM A;  3NZ4 A;  1U16 A;  1K7W A;  4A15 A;  1XL7 A;  4NSL A;  2X75 A;  1TJ7 A;  3QBP A;  1C3U A;  1W27 A;  4C5R A;  1RE5 A;  1TJW A;  1GK3 A;  2O78 A;  1KQ7 A;  4ADM A;  1VDK A;  2O7B A;  4C5U A;  1TJV A;  1T6P A;  1JSW A;  4APB A;  4V2R A;  3OCF A;  2QGA B;  1J3U A;  2O7F A;  4NLE A;  2PTQ A;  4FLC A;  5EYV A;  2HVG A;  3KDZ A;  2PTR A;  4BAB A;  2E9F A;  1HY0 A;  1GKJ A;  2OHY A;  3R6V A;  4EFC A;  2RJS A;  1Q5N A;  1XMD A;  1FUR A;  1XWO A;  5HW2 A;  1T6J A;  2O7D A;  1Y2M A;  4BAA A;  4C6G A;  4V2Q A;  2VSF A;  2QVE A;  2FUS A;  1B8F A;  3KDY A;  1HY1 A;  4ADL A;  3RD8 A;  2NYF A;  3R6Q A;  1FUP A;  3OCE A;  3CRV A;  1AUW A;  1C3C A;  3TV2 A;  3R6Y A;  2J91 A;  4MX2 A;  1YIS A;  4C5S A;  5EYT A;  1K62 A;  3CZO A;  3GTD A;  4CQ5 A;  1FUO A;  5D6B A;  1I0A A;  3RRP A;  2VD6 A;  3GZH A;  1YFE A;  2YII A;  4EEI A;  1DCN A;  2VL7 A;  3CRW 1;  1FUQ A;  3UNV A;  1EB4 A;  3BHG A;  2RJR A;  1GK2 A;  5H8W A;  2O6Y A;  4HGV A;  5F92 A;  3C8T A; 
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