2X75A

Staphylococcus aureus adenylosuccinate lyase
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
430
structure length
427
Chain Sequence
IERYSREEMSNIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESITTKEELDECFDPKHHLNQVDTIFERAGLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords ADENYLOSUCCINATE LYASE
publication title Structure of Staphylococcus Aureus Adenylosuccinate Lyase (Purb) and Assessment of its Potential as a Target for Structure-Based Inhibitor Discovery.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 165
structure length 427
sequence length 430
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2010-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2x75A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2x75A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2x75A02
1KQ7A 3UNVA 2FUSA 2PTSA 1TJ7A 1K7WA 3GZHA 3KDYA 5EYVA 2PTRA 1XWOA 2NYFA 1K62A 4ADLA 5EYTA 4MX2A 1HY1A 2OHYA 3R6YA 1W27A 2O7EA 4V2QA 1FURA 4HGVA 1TJWA 2VD6A 1FUQA 4APAA 1I0AA 2QVEA 1Q5NA 1C3CA 2O7DA 1U15A 2HVGA 1AUWA 2PFMA 5HW2A 4C5UA 2O7FA 3BHGA 4BAAA 1T6JA 1TJVA 1YFMA 3RD8A 3OCEA 2O7BA 3CZOA 4BABA 3NZ4A 2O6YA 2QGAB 3R6QA 3C8TA 4ADMA 2O78A 2PTQA 4APBA 4NSLA 1B8FA 3GTDA 2YIIA 1U16A 2J91A 2RJSA 5F91A 1C3UA 1VDKA 3E04A 3R6VA 1Y2MA 3TV2A 4FFXA 3RRPA 1GKMA 4C5SA 1JSWA 1DCNA 2X75A 3KDZA 4V2RA 1HY0A 4FLCA 1FUOA 4C6GA 1EB4A 1TJUA 1T6PA 1GKJA 1FUPA 1YFEA 4C5RA 3OCFA 2E9FA 4EFCA 1J3UA 1GK2A 1YISA 5F92A 3QBPA 3NO9A 2RJRA 1RE5A 1GK3A 4CQ5A 1DOFA 4NLEA 5D6BA 4EEIA 2NYNA
chains in the Genus database with same CATH superfamily
1KQ7A 2JAUA 3UNVA 2FUSA 2PTSA 1TJ7A 4WNLA 4MUMA 1K7WA 3GZHA 3KDYA 5EYVA 2D28C 2PTRA 1XWOA 2NYFA 1K62A 4ADLA 3CI0K 5EYTA 4MX2A 1HY1A 2OHYA 3R6YA 1W27A 2O7EA 4V2QA 1FURA 3CRW1 4HGVA 1TJWA 4E88A 2VD6A 2RCNA 2FELA 1FUQA 4APAA 1I0AA 2QVEA 5M0JA 1Q5NA 1C3CA 4NFLA 2O7DA 1XMDA 1U15A 2HVGA 1AUWA 2PFMA 5HW2A 4C5UA 4YIKA 3BWVA 2O7FA 1XMCA 4A15A 3BHGA 4L6AA 4BAAA 4L57A 4MWOA 1T6JA 1TJVA 1IW7D 1YFMA 3RD8A 3OCEA 2O7BA 3CZOA 4BABA 3NZ4A 5M0IA 2O6YA 3U13A 2QGAB 3R6QA 3C8TA 4ADMA 2VSFA 3F4RA 2O78A 2PTQA 1MH9A 2JAWA 4APBA 1Z4IA 4NSLA 1B8FA 3U19A 3GTDA 2YIIA 1U16A 2J91A 2FENA 2RJSA 5F91A 1C3UA 1VDKA 3E04A 3R6VA 1Z4JA 1Y2MA 3TV2A 4FFXA 3RRPA 1GKMA 4C5SA 1JSWA 1DCNA 1Z4QA 2X75A 3KDZA 1XL8A 4V2RA 1HY0A 5H8WA 4FLCA 4YIHA 3F4TA 1FUOA 4C6GA 1EB4A 1TJUA 1T6PA 1Z4PX 1GKJA 1FUPA 3F4SA 1YFEA 4C5RA 3OCFA 1U0LA 1Q91A 2E9FA 4EFCA 2YV5A 2JARA 1J3UA 1GK2A 1Z4LA 1XL7A 1YISA 5F92A 1T9HA 2JAOA 3QBPA 3NO9A 2RJRA 1RE5A 1Z4MA 4L6CA 2VL7A 2I7DA 1Q92A 4IQJM 3CRVA 2D27A 1GK3A 4CQ5A 1Z4KA 1DOFA 4NLEA 5D6BA 4EEIA 2NYNA 1XLYA
chains in the Genus database with same CATH topology
1KQ7A 3UNVA 2FUSA 2PTSA 1TJ7A 1K7WA 3GZHA 3KDYA 5EYVA 2PTRA 1XWOA 2NYFA 1K62A 4ADLA 5EYTA 4MX2A 1HY1A 2OHYA 3R6YA 1W27A 2O7EA 4V2QA 1FURA 4HGVA 1TJWA 2VD6A 1FUQA 4APAA 1I0AA 2QVEA 1Q5NA 1C3CA 2O7DA 1U15A 2HVGA 1AUWA 2PFMA 5HW2A 4C5UA 2O7FA 3BHGA 4BAAA 1T6JA 1TJVA 1YFMA 3RD8A 3OCEA 2O7BA 3CZOA 4BABA 3NZ4A 2O6YA 2QGAB 3R6QA 3C8TA 4ADMA 2O78A 2PTQA 4APBA 4NSLA 1B8FA 3GTDA 2YIIA 1U16A 2J91A 2RJSA 5F91A 1C3UA 1VDKA 3E04A 3R6VA 1Y2MA 3TV2A 4FFXA 3RRPA 1GKMA 4C5SA 1JSWA 1DCNA 2X75A 3KDZA 4V2RA 1HY0A 4FLCA 1FUOA 4C6GA 1EB4A 1TJUA 1T6PA 1GKJA 1FUPA 1YFEA 4C5RA 3OCFA 2E9FA 4EFCA 1J3UA 1GK2A 1YISA 5F92A 3QBPA 3NO9A 2RJRA 1RE5A 1GK3A 4CQ5A 1DOFA 4NLEA 5D6BA 4EEIA 2NYNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KQ7 A;  3UNV A;  2FUS A;  2PTS A;  1TJ7 A;  1K7W A;  3GZH A;  3KDY A;  5EYV A;  2PTR A;  1XWO A;  2NYF A;  1K62 A;  4ADL A;  5EYT A;  4MX2 A;  1HY1 A;  2OHY A;  3R6Y A;  1W27 A;  2O7E A;  4V2Q A;  1FUR A;  4HGV A;  1TJW A;  2VD6 A;  1FUQ A;  4APA A;  1I0A A;  2QVE A;  1Q5N A;  1C3C A;  2O7D A;  1U15 A;  2HVG A;  1AUW A;  2PFM A;  5HW2 A;  4C5U A;  2O7F A;  3BHG A;  4BAA A;  1T6J A;  1TJV A;  1YFM A;  3RD8 A;  3OCE A;  2O7B A;  3CZO A;  4BAB A;  3NZ4 A;  2O6Y A;  2QGA B;  3R6Q A;  3C8T A;  4ADM A;  2O78 A;  2PTQ A;  4APB A;  4NSL A;  1B8F A;  3GTD A;  2YII A;  1U16 A;  2J91 A;  2RJS A;  5F91 A;  1C3U A;  1VDK A;  3E04 A;  3R6V A;  1Y2M A;  3TV2 A;  4FFX A;  3RRP A;  1GKM A;  4C5S A;  1JSW A;  1DCN A;  2X75 A;  3KDZ A;  4V2R A;  1HY0 A;  4FLC A;  1FUO A;  4C6G A;  1EB4 A;  1TJU A;  1T6P A;  1GKJ A;  1FUP A;  1YFE A;  4C5R A;  3OCF A;  2E9F A;  4EFC A;  1J3U A;  1GK2 A;  1YIS A;  5F92 A;  3QBP A;  3NO9 A;  2RJR A;  1RE5 A;  1GK3 A;  4CQ5 A;  1DOF A;  4NLE A;  5D6B A;  4EEI A;  2NYN A; 
#chains in the Genus database with same CATH topology
 1KQ7 A;  2JAU A;  3UNV A;  2FUS A;  2PTS A;  1TJ7 A;  4WNL A;  4MUM A;  1K7W A;  3GZH A;  3KDY A;  5EYV A;  2D28 C;  2PTR A;  1XWO A;  2NYF A;  1K62 A;  4ADL A;  3CI0 K;  5EYT A;  4MX2 A;  1HY1 A;  2OHY A;  3R6Y A;  1W27 A;  2O7E A;  4V2Q A;  1FUR A;  3CRW 1;  4HGV A;  1TJW A;  4E88 A;  2VD6 A;  2RCN A;  2FEL A;  1FUQ A;  4APA A;  1I0A A;  2QVE A;  5M0J A;  1Q5N A;  1C3C A;  4NFL A;  2O7D A;  1XMD A;  1U15 A;  2HVG A;  1AUW A;  2PFM A;  5HW2 A;  4C5U A;  4YIK A;  3BWV A;  2O7F A;  1XMC A;  4A15 A;  3BHG A;  4L6A A;  4BAA A;  4L57 A;  4MWO A;  1T6J A;  1TJV A;  1IW7 D;  1YFM A;  3RD8 A;  3OCE A;  2O7B A;  3CZO A;  4BAB A;  3NZ4 A;  5M0I A;  2O6Y A;  3U13 A;  2QGA B;  3R6Q A;  3C8T A;  4ADM A;  2VSF A;  3F4R A;  2O78 A;  2PTQ A;  1MH9 A;  2JAW A;  4APB A;  1Z4I A;  4NSL A;  1B8F A;  3U19 A;  3GTD A;  2YII A;  1U16 A;  2J91 A;  2FEN A;  2RJS A;  5F91 A;  1C3U A;  1VDK A;  3E04 A;  3R6V A;  1Z4J A;  1Y2M A;  3TV2 A;  4FFX A;  3RRP A;  1GKM A;  4C5S A;  1JSW A;  1DCN A;  1Z4Q A;  2X75 A;  3KDZ A;  1XL8 A;  4V2R A;  1HY0 A;  5H8W A;  4FLC A;  4YIH A;  3F4T A;  1FUO A;  4C6G A;  1EB4 A;  1TJU A;  1T6P A;  1Z4P X;  1GKJ A;  1FUP A;  3F4S A;  1YFE A;  4C5R A;  3OCF A;  1U0L A;  1Q91 A;  2E9F A;  4EFC A;  2YV5 A;  2JAR A;  1J3U A;  1GK2 A;  1Z4L A;  1XL7 A;  1YIS A;  5F92 A;  1T9H A;  2JAO A;  3QBP A;  3NO9 A;  2RJR A;  1RE5 A;  1Z4M A;  4L6C A;  2VL7 A;  2I7D A;  1Q92 A;  4IQJ M;  3CRV A;  2D27 A;  1GK3 A;  4CQ5 A;  1Z4K A;  1DOF A;  4NLE A;  5D6B A;  4EEI A;  2NYN A;  1XLY A; 
#chains in the Genus database with same CATH homology
 1KQ7 A;  3UNV A;  2FUS A;  2PTS A;  1TJ7 A;  1K7W A;  3GZH A;  3KDY A;  5EYV A;  2PTR A;  1XWO A;  2NYF A;  1K62 A;  4ADL A;  5EYT A;  4MX2 A;  1HY1 A;  2OHY A;  3R6Y A;  1W27 A;  2O7E A;  4V2Q A;  1FUR A;  4HGV A;  1TJW A;  2VD6 A;  1FUQ A;  4APA A;  1I0A A;  2QVE A;  1Q5N A;  1C3C A;  2O7D A;  1U15 A;  2HVG A;  1AUW A;  2PFM A;  5HW2 A;  4C5U A;  2O7F A;  3BHG A;  4BAA A;  1T6J A;  1TJV A;  1YFM A;  3RD8 A;  3OCE A;  2O7B A;  3CZO A;  4BAB A;  3NZ4 A;  2O6Y A;  2QGA B;  3R6Q A;  3C8T A;  4ADM A;  2O78 A;  2PTQ A;  4APB A;  4NSL A;  1B8F A;  3GTD A;  2YII A;  1U16 A;  2J91 A;  2RJS A;  5F91 A;  1C3U A;  1VDK A;  3E04 A;  3R6V A;  1Y2M A;  3TV2 A;  4FFX A;  3RRP A;  1GKM A;  4C5S A;  1JSW A;  1DCN A;  2X75 A;  3KDZ A;  4V2R A;  1HY0 A;  4FLC A;  1FUO A;  4C6G A;  1EB4 A;  1TJU A;  1T6P A;  1GKJ A;  1FUP A;  1YFE A;  4C5R A;  3OCF A;  2E9F A;  4EFC A;  1J3U A;  1GK2 A;  1YIS A;  5F92 A;  3QBP A;  3NO9 A;  2RJR A;  1RE5 A;  1GK3 A;  4CQ5 A;  1DOF A;  4NLE A;  5D6B A;  4EEI A;  2NYN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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