1JSWA

Native l-aspartate ammonia lyase
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
459
structure length
459
Chain Sequence
MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLIKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of L-aspartate ammonia-lyase from Escherichia coli.
pubmed doi rcsb
molecule tags Amino acid ammonia-lyase
molecule keywords L-ASPARTATE AMMONIA-LYASE
total genus 139
structure length 459
sequence length 459
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.1: Aspartate ammonia-lyase.
pdb deposition date 1997-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1jswA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1jswA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1jswA02
1U16A 1GKMA 2E9FA 1K62A 2PTQA 2J91A 2QVEA 4CQ5A 4V2RA 3NO9A 4C5RA 1EB4A 1K7WA 1GK3A 1VDKA 1YFMA 1J3UA 1Q5NA 5EYVA 4EFCA 1AUWA 1FUPA 1RE5A 1C3CA 1W27A 4V2QA 1TJ7A 4ADMA 1TJUA 5F91A 1I0AA 1JSWA 2OHYA 4APAA 1U15A 4C5SA 2PTRA 1B8FA 1FURA 1Y2MA 2NYFA 4NSLA 1TJWA 1YISA 2PFMA 4C5UA 3KDZA 3RD8A 1YFEA 3CZOA 1T6PA 4C6GA 3OCFA 2HVGA 2NYNA 1DOFA 1DCNA 3QBPA 2X75A 3R6QA 4BABA 2RJRA 4EEIA 1GKJA 3OCEA 4FFXA 3BHGA 2RJSA 2O78A 1FUOA 2QGAB 4APBA 1C3UA 1KQ7A 1TJVA 3NZ4A 5EYTA 4NLEA 2O7FA 1XWOA 3C8TA 1HY1A 2FUSA 4ADLA 3KDYA 2O6YA 1FUQA 2O7EA 1GK2A 3GZHA 2VD6A 2YIIA 3R6VA 3E04A 4BAAA 2O7DA 3UNVA 3R6YA 4MX2A 1T6JA 3GTDA 5HW2A 2PTSA 3TV2A 5F92A 1HY0A 3RRPA 5D6BA 4FLCA 2O7BA 4HGVA
chains in the Genus database with same CATH superfamily
4L6AA 1Z4JA 1XL8A 1U16A 1GKMA 2E9FA 1XMCA 1K62A 2PTQA 2J91A 4WNLA 2QVEA 4CQ5A 4V2RA 3NO9A 3BWVA 4C5RA 2FENA 1EB4A 1K7WA 1GK3A 4NFLA 1VDKA 1U0LA 1YFMA 3F4SA 1J3UA 2JAWA 1Q5NA 5EYVA 4MWOA 4EFCA 1AUWA 1FUPA 5H8WA 1MH9A 1RE5A 1C3CA 2YV5A 1W27A 1Z4LA 4V2QA 1TJ7A 4ADMA 1TJUA 2D27A 1I0AA 5F91A 1JSWA 4L6CA 2OHYA 3U19A 4MUMA 2VL7A 1Z4MA 4APAA 1U15A 4C5SA 2I7DA 2PTRA 1B8FA 1FURA 1Y2MA 2NYFA 4NSLA 1TJWA 1IW7D 1YISA 2PFMA 4C5UA 3F4TA 3KDZA 1XLYA 4L57A 3RD8A 1YFEA 3CZOA 1T6PA 4C6GA 3OCFA 2HVGA 3CRVA 1XL7A 2NYNA 1DOFA 2FELA 1DCNA 3QBPA 2X75A 3R6QA 4BABA 2RJRA 3CRW1 4EEIA 1Q91A 1GKJA 3OCEA 4FFXA 1Z4KA 2JAOA 3BHGA 2RJSA 1Z4PX 2O78A 1FUOA 4YIKA 1T9HA 2D28C 2QGAB 4APBA 2JAUA 1C3UA 3CI0K 1KQ7A 1TJVA 3NZ4A 3U13A 5EYTA 4NLEA 2O7FA 1XWOA 3C8TA 1HY1A 2FUSA 4ADLA 1Q92A 3KDYA 1Z4IA 1FUQA 2O7EA 2O6YA 1GK2A 3GZHA 2VD6A 2YIIA 3R6VA 4E88A 3E04A 4BAAA 4A15A 2O7DA 2JARA 3UNVA 3R6YA 4MX2A 2VSFA 1T6JA 3GTDA 5M0IA 5HW2A 2PTSA 3TV2A 5M0JA 2RCNA 5F92A 1HY0A 1XMDA 3RRPA 5D6BA 1Z4QA 4FLCA 2O7BA 4HGVA 4IQJM 4YIHA 3F4RA
chains in the Genus database with same CATH topology
1U16A 1GKMA 2E9FA 1K62A 2PTQA 2J91A 2QVEA 4CQ5A 4V2RA 3NO9A 4C5RA 1EB4A 1K7WA 1GK3A 1VDKA 1YFMA 1J3UA 1Q5NA 5EYVA 4EFCA 1AUWA 1FUPA 1RE5A 1C3CA 1W27A 4V2QA 1TJ7A 4ADMA 1TJUA 5F91A 1I0AA 1JSWA 2OHYA 4APAA 1U15A 4C5SA 2PTRA 1B8FA 1FURA 1Y2MA 2NYFA 4NSLA 1TJWA 1YISA 2PFMA 4C5UA 3KDZA 3RD8A 1YFEA 3CZOA 1T6PA 4C6GA 3OCFA 2HVGA 2NYNA 1DOFA 1DCNA 3QBPA 2X75A 3R6QA 4BABA 2RJRA 4EEIA 1GKJA 3OCEA 4FFXA 3BHGA 2RJSA 2O78A 1FUOA 2QGAB 4APBA 1C3UA 1KQ7A 1TJVA 3NZ4A 5EYTA 4NLEA 2O7FA 1XWOA 3C8TA 1HY1A 2FUSA 4ADLA 3KDYA 2O6YA 1FUQA 2O7EA 1GK2A 3GZHA 2VD6A 2YIIA 3R6VA 3E04A 4BAAA 2O7DA 3UNVA 3R6YA 4MX2A 1T6JA 3GTDA 5HW2A 2PTSA 3TV2A 5F92A 1HY0A 3RRPA 5D6BA 4FLCA 2O7BA 4HGVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U16 A;  1GKM A;  2E9F A;  1K62 A;  2PTQ A;  2J91 A;  2QVE A;  4CQ5 A;  4V2R A;  3NO9 A;  4C5R A;  1EB4 A;  1K7W A;  1GK3 A;  1VDK A;  1YFM A;  1J3U A;  1Q5N A;  5EYV A;  4EFC A;  1AUW A;  1FUP A;  1RE5 A;  1C3C A;  1W27 A;  4V2Q A;  1TJ7 A;  4ADM A;  1TJU A;  5F91 A;  1I0A A;  1JSW A;  2OHY A;  4APA A;  1U15 A;  4C5S A;  2PTR A;  1B8F A;  1FUR A;  1Y2M A;  2NYF A;  4NSL A;  1TJW A;  1YIS A;  2PFM A;  4C5U A;  3KDZ A;  3RD8 A;  1YFE A;  3CZO A;  1T6P A;  4C6G A;  3OCF A;  2HVG A;  2NYN A;  1DOF A;  1DCN A;  3QBP A;  2X75 A;  3R6Q A;  4BAB A;  2RJR A;  4EEI A;  1GKJ A;  3OCE A;  4FFX A;  3BHG A;  2RJS A;  2O78 A;  1FUO A;  2QGA B;  4APB A;  1C3U A;  1KQ7 A;  1TJV A;  3NZ4 A;  5EYT A;  4NLE A;  2O7F A;  1XWO A;  3C8T A;  1HY1 A;  2FUS A;  4ADL A;  3KDY A;  2O6Y A;  1FUQ A;  2O7E A;  1GK2 A;  3GZH A;  2VD6 A;  2YII A;  3R6V A;  3E04 A;  4BAA A;  2O7D A;  3UNV A;  3R6Y A;  4MX2 A;  1T6J A;  3GTD A;  5HW2 A;  2PTS A;  3TV2 A;  5F92 A;  1HY0 A;  3RRP A;  5D6B A;  4FLC A;  2O7B A;  4HGV A; 
#chains in the Genus database with same CATH topology
 4L6A A;  1Z4J A;  1XL8 A;  1U16 A;  1GKM A;  2E9F A;  1XMC A;  1K62 A;  2PTQ A;  2J91 A;  4WNL A;  2QVE A;  4CQ5 A;  4V2R A;  3NO9 A;  3BWV A;  4C5R A;  2FEN A;  1EB4 A;  1K7W A;  1GK3 A;  4NFL A;  1VDK A;  1U0L A;  1YFM A;  3F4S A;  1J3U A;  2JAW A;  1Q5N A;  5EYV A;  4MWO A;  4EFC A;  1AUW A;  1FUP A;  5H8W A;  1MH9 A;  1RE5 A;  1C3C A;  2YV5 A;  1W27 A;  1Z4L A;  4V2Q A;  1TJ7 A;  4ADM A;  1TJU A;  2D27 A;  1I0A A;  5F91 A;  1JSW A;  4L6C A;  2OHY A;  3U19 A;  4MUM A;  2VL7 A;  1Z4M A;  4APA A;  1U15 A;  4C5S A;  2I7D A;  2PTR A;  1B8F A;  1FUR A;  1Y2M A;  2NYF A;  4NSL A;  1TJW A;  1IW7 D;  1YIS A;  2PFM A;  4C5U A;  3F4T A;  3KDZ A;  1XLY A;  4L57 A;  3RD8 A;  1YFE A;  3CZO A;  1T6P A;  4C6G A;  3OCF A;  2HVG A;  3CRV A;  1XL7 A;  2NYN A;  1DOF A;  2FEL A;  1DCN A;  3QBP A;  2X75 A;  3R6Q A;  4BAB A;  2RJR A;  3CRW 1;  4EEI A;  1Q91 A;  1GKJ A;  3OCE A;  4FFX A;  1Z4K A;  2JAO A;  3BHG A;  2RJS A;  1Z4P X;  2O78 A;  1FUO A;  4YIK A;  1T9H A;  2D28 C;  2QGA B;  4APB A;  2JAU A;  1C3U A;  3CI0 K;  1KQ7 A;  1TJV A;  3NZ4 A;  3U13 A;  5EYT A;  4NLE A;  2O7F A;  1XWO A;  3C8T A;  1HY1 A;  2FUS A;  4ADL A;  1Q92 A;  3KDY A;  1Z4I A;  1FUQ A;  2O7E A;  2O6Y A;  1GK2 A;  3GZH A;  2VD6 A;  2YII A;  3R6V A;  4E88 A;  3E04 A;  4BAA A;  4A15 A;  2O7D A;  2JAR A;  3UNV A;  3R6Y A;  4MX2 A;  2VSF A;  1T6J A;  3GTD A;  5M0I A;  5HW2 A;  2PTS A;  3TV2 A;  5M0J A;  2RCN A;  5F92 A;  1HY0 A;  1XMD A;  3RRP A;  5D6B A;  1Z4Q A;  4FLC A;  2O7B A;  4HGV A;  4IQJ M;  4YIH A;  3F4R A; 
#chains in the Genus database with same CATH homology
 1U16 A;  1GKM A;  2E9F A;  1K62 A;  2PTQ A;  2J91 A;  2QVE A;  4CQ5 A;  4V2R A;  3NO9 A;  4C5R A;  1EB4 A;  1K7W A;  1GK3 A;  1VDK A;  1YFM A;  1J3U A;  1Q5N A;  5EYV A;  4EFC A;  1AUW A;  1FUP A;  1RE5 A;  1C3C A;  1W27 A;  4V2Q A;  1TJ7 A;  4ADM A;  1TJU A;  5F91 A;  1I0A A;  1JSW A;  2OHY A;  4APA A;  1U15 A;  4C5S A;  2PTR A;  1B8F A;  1FUR A;  1Y2M A;  2NYF A;  4NSL A;  1TJW A;  1YIS A;  2PFM A;  4C5U A;  3KDZ A;  3RD8 A;  1YFE A;  3CZO A;  1T6P A;  4C6G A;  3OCF A;  2HVG A;  2NYN A;  1DOF A;  1DCN A;  3QBP A;  2X75 A;  3R6Q A;  4BAB A;  2RJR A;  4EEI A;  1GKJ A;  3OCE A;  4FFX A;  3BHG A;  2RJS A;  2O78 A;  1FUO A;  2QGA B;  4APB A;  1C3U A;  1KQ7 A;  1TJV A;  3NZ4 A;  5EYT A;  4NLE A;  2O7F A;  1XWO A;  3C8T A;  1HY1 A;  2FUS A;  4ADL A;  3KDY A;  2O6Y A;  1FUQ A;  2O7E A;  1GK2 A;  3GZH A;  2VD6 A;  2YII A;  3R6V A;  3E04 A;  4BAA A;  2O7D A;  3UNV A;  3R6Y A;  4MX2 A;  1T6J A;  3GTD A;  5HW2 A;  2PTS A;  3TV2 A;  5F92 A;  1HY0 A;  3RRP A;  5D6B A;  4FLC A;  2O7B A;  4HGV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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