1JSWA

Native l-aspartate ammonia lyase
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
459
structure length
459
Chain Sequence
MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLIKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords L-ASPARTATE AMMONIA-LYASE
publication title The structure of L-aspartate ammonia-lyase from Escherichia coli.
pubmed doi rcsb
molecule tags Amino acid ammonia-lyase
total genus 139
structure length 459
sequence length 459
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.1: Aspartate ammonia-lyase.
pdb deposition date 1997-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1jswA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1jswA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1jswA02
3R6YA 4FFXA 4HGVA 1YFMA 3UNVA 2O78A 2O6YA 1AUWA 4V2RA 1GK3A 5D6BA 2YIIA 2PTRA 5EYTA 3E04A 2O7BA 1I0AA 4MX2A 3CZOA 3OCEA 1FUOA 1KQ7A 1TJVA 1VDKA 3QBPA 2NYFA 2O7DA 5EYVA 3RD8A 5F91A 4ADLA 1HY0A 2X75A 1HY1A 2RJRA 2NYNA 4C5SA 1W27A 4ADMA 3KDZA 1YFEA 2E9FA 3C8TA 2O7EA 2RJSA 2O7FA 3NZ4A 1DCNA 1GK2A 1TJWA 2QVEA 1TJUA 3NO9A 2VD6A 1Y2MA 2QGAB 3KDYA 4APBA 1XWOA 3TV2A 2J91A 1T6JA 3R6VA 1FUPA 4C6GA 5HW2A 2OHYA 2PTSA 1U16A 3R6QA 1T6PA 4NLEA 1GKJA 4CQ5A 1TJ7A 1YISA 1GKMA 4FLCA 2PFMA 4BAAA 2FUSA 4APAA 1FURA 1FUQA 1C3CA 1RE5A 1J3UA 3OCFA 4NSLA 1C3UA 1K7WA 2HVGA 1EB4A 1Q5NA 4C5UA 1U15A 1B8FA 3GZHA 3BHGA 3GTDA 4EEIA 1K62A 4V2QA 4EFCA 5F92A 1DOFA 3RRPA 4C5RA 2PTQA 1JSWA 4BABA
chains in the Genus database with same CATH superfamily
2I7DA 3R6YA 4FFXA 2D28C 4MWOA 4L6AA 4E88A 5M0IA 4HGVA 1YFMA 3UNVA 1XMCA 1IW7D 2O78A 2O6YA 3F4SA 1T9HA 1AUWA 1XLYA 4V2RA 1GK3A 5D6BA 2YIIA 2JAWA 1Z4MA 1Z4QA 2PTRA 5EYTA 3E04A 1Z4JA 2O7BA 1I0AA 4MX2A 3BWVA 3CI0K 1XMDA 3CZOA 3OCEA 1FUOA 4YIKA 1KQ7A 4NFLA 1TJVA 1VDKA 3QBPA 2NYFA 2O7DA 5EYVA 3RD8A 5F91A 4ADLA 3CRW1 1HY0A 2X75A 1HY1A 2RJRA 2NYNA 3F4RA 4C5SA 1W27A 4ADMA 3KDZA 1YFEA 1Z4LA 2E9FA 3C8TA 2O7EA 2RJSA 2O7FA 4YIHA 3NZ4A 1DCNA 1Q91A 4L57A 1Q92A 1GK2A 3U19A 1TJWA 1Z4IA 2QVEA 1TJUA 3NO9A 2JARA 4IQJM 2VD6A 1Y2MA 2QGAB 3KDYA 4APBA 1XWOA 3CRVA 3TV2A 1Z4PX 2D27A 2J91A 1T6JA 3R6VA 1FUPA 4C6GA 5HW2A 2OHYA 2PTSA 1U16A 3R6QA 1T6PA 4NLEA 1Z4KA 2FENA 1GKJA 4CQ5A 1TJ7A 4L6CA 1YISA 1GKMA 4FLCA 2VL7A 2PFMA 4BAAA 2FUSA 4APAA 2YV5A 1FURA 5H8WA 1FUQA 1U0LA 1C3CA 1RE5A 2RCNA 1J3UA 4MUMA 3OCFA 4NSLA 4A15A 1C3UA 1K7WA 2HVGA 1MH9A 1EB4A 1Q5NA 1XL8A 2VSFA 2JAUA 4C5UA 1U15A 1B8FA 2JAOA 3GZHA 3BHGA 3GTDA 4EEIA 1K62A 1XL7A 4EFCA 5F92A 4V2QA 2FELA 3U13A 1DOFA 3RRPA 4C5RA 4WNLA 2PTQA 3F4TA 1JSWA 5M0JA 4BABA
chains in the Genus database with same CATH topology
3R6YA 4FFXA 4HGVA 1YFMA 3UNVA 2O78A 2O6YA 1AUWA 4V2RA 1GK3A 5D6BA 2YIIA 2PTRA 5EYTA 3E04A 2O7BA 1I0AA 4MX2A 3CZOA 3OCEA 1FUOA 1KQ7A 1TJVA 1VDKA 3QBPA 2NYFA 2O7DA 5EYVA 3RD8A 5F91A 4ADLA 1HY0A 2X75A 1HY1A 2RJRA 2NYNA 4C5SA 1W27A 4ADMA 3KDZA 1YFEA 2E9FA 3C8TA 2O7EA 2RJSA 2O7FA 3NZ4A 1DCNA 1GK2A 1TJWA 2QVEA 1TJUA 3NO9A 2VD6A 1Y2MA 2QGAB 3KDYA 4APBA 1XWOA 3TV2A 2J91A 1T6JA 3R6VA 1FUPA 4C6GA 5HW2A 2OHYA 2PTSA 1U16A 3R6QA 1T6PA 4NLEA 1GKJA 4CQ5A 1TJ7A 1YISA 1GKMA 4FLCA 2PFMA 4BAAA 2FUSA 4APAA 1FURA 1FUQA 1C3CA 1RE5A 1J3UA 3OCFA 4NSLA 1C3UA 1K7WA 2HVGA 1EB4A 1Q5NA 4C5UA 1U15A 1B8FA 3GZHA 3BHGA 3GTDA 4EEIA 1K62A 4V2QA 4EFCA 5F92A 1DOFA 3RRPA 4C5RA 2PTQA 1JSWA 4BABA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R6Y A;  4FFX A;  4HGV A;  1YFM A;  3UNV A;  2O78 A;  2O6Y A;  1AUW A;  4V2R A;  1GK3 A;  5D6B A;  2YII A;  2PTR A;  5EYT A;  3E04 A;  2O7B A;  1I0A A;  4MX2 A;  3CZO A;  3OCE A;  1FUO A;  1KQ7 A;  1TJV A;  1VDK A;  3QBP A;  2NYF A;  2O7D A;  5EYV A;  3RD8 A;  5F91 A;  4ADL A;  1HY0 A;  2X75 A;  1HY1 A;  2RJR A;  2NYN A;  4C5S A;  1W27 A;  4ADM A;  3KDZ A;  1YFE A;  2E9F A;  3C8T A;  2O7E A;  2RJS A;  2O7F A;  3NZ4 A;  1DCN A;  1GK2 A;  1TJW A;  2QVE A;  1TJU A;  3NO9 A;  2VD6 A;  1Y2M A;  2QGA B;  3KDY A;  4APB A;  1XWO A;  3TV2 A;  2J91 A;  1T6J A;  3R6V A;  1FUP A;  4C6G A;  5HW2 A;  2OHY A;  2PTS A;  1U16 A;  3R6Q A;  1T6P A;  4NLE A;  1GKJ A;  4CQ5 A;  1TJ7 A;  1YIS A;  1GKM A;  4FLC A;  2PFM A;  4BAA A;  2FUS A;  4APA A;  1FUR A;  1FUQ A;  1C3C A;  1RE5 A;  1J3U A;  3OCF A;  4NSL A;  1C3U A;  1K7W A;  2HVG A;  1EB4 A;  1Q5N A;  4C5U A;  1U15 A;  1B8F A;  3GZH A;  3BHG A;  3GTD A;  4EEI A;  1K62 A;  4V2Q A;  4EFC A;  5F92 A;  1DOF A;  3RRP A;  4C5R A;  2PTQ A;  1JSW A;  4BAB A; 
#chains in the Genus database with same CATH topology
 2I7D A;  3R6Y A;  4FFX A;  2D28 C;  4MWO A;  4L6A A;  4E88 A;  5M0I A;  4HGV A;  1YFM A;  3UNV A;  1XMC A;  1IW7 D;  2O78 A;  2O6Y A;  3F4S A;  1T9H A;  1AUW A;  1XLY A;  4V2R A;  1GK3 A;  5D6B A;  2YII A;  2JAW A;  1Z4M A;  1Z4Q A;  2PTR A;  5EYT A;  3E04 A;  1Z4J A;  2O7B A;  1I0A A;  4MX2 A;  3BWV A;  3CI0 K;  1XMD A;  3CZO A;  3OCE A;  1FUO A;  4YIK A;  1KQ7 A;  4NFL A;  1TJV A;  1VDK A;  3QBP A;  2NYF A;  2O7D A;  5EYV A;  3RD8 A;  5F91 A;  4ADL A;  3CRW 1;  1HY0 A;  2X75 A;  1HY1 A;  2RJR A;  2NYN A;  3F4R A;  4C5S A;  1W27 A;  4ADM A;  3KDZ A;  1YFE A;  1Z4L A;  2E9F A;  3C8T A;  2O7E A;  2RJS A;  2O7F A;  4YIH A;  3NZ4 A;  1DCN A;  1Q91 A;  4L57 A;  1Q92 A;  1GK2 A;  3U19 A;  1TJW A;  1Z4I A;  2QVE A;  1TJU A;  3NO9 A;  2JAR A;  4IQJ M;  2VD6 A;  1Y2M A;  2QGA B;  3KDY A;  4APB A;  1XWO A;  3CRV A;  3TV2 A;  1Z4P X;  2D27 A;  2J91 A;  1T6J A;  3R6V A;  1FUP A;  4C6G A;  5HW2 A;  2OHY A;  2PTS A;  1U16 A;  3R6Q A;  1T6P A;  4NLE A;  1Z4K A;  2FEN A;  1GKJ A;  4CQ5 A;  1TJ7 A;  4L6C A;  1YIS A;  1GKM A;  4FLC A;  2VL7 A;  2PFM A;  4BAA A;  2FUS A;  4APA A;  2YV5 A;  1FUR A;  5H8W A;  1FUQ A;  1U0L A;  1C3C A;  1RE5 A;  2RCN A;  1J3U A;  4MUM A;  3OCF A;  4NSL A;  4A15 A;  1C3U A;  1K7W A;  2HVG A;  1MH9 A;  1EB4 A;  1Q5N A;  1XL8 A;  2VSF A;  2JAU A;  4C5U A;  1U15 A;  1B8F A;  2JAO A;  3GZH A;  3BHG A;  3GTD A;  4EEI A;  1K62 A;  1XL7 A;  4EFC A;  5F92 A;  4V2Q A;  2FEL A;  3U13 A;  1DOF A;  3RRP A;  4C5R A;  4WNL A;  2PTQ A;  3F4T A;  1JSW A;  5M0J A;  4BAB A; 
#chains in the Genus database with same CATH homology
 3R6Y A;  4FFX A;  4HGV A;  1YFM A;  3UNV A;  2O78 A;  2O6Y A;  1AUW A;  4V2R A;  1GK3 A;  5D6B A;  2YII A;  2PTR A;  5EYT A;  3E04 A;  2O7B A;  1I0A A;  4MX2 A;  3CZO A;  3OCE A;  1FUO A;  1KQ7 A;  1TJV A;  1VDK A;  3QBP A;  2NYF A;  2O7D A;  5EYV A;  3RD8 A;  5F91 A;  4ADL A;  1HY0 A;  2X75 A;  1HY1 A;  2RJR A;  2NYN A;  4C5S A;  1W27 A;  4ADM A;  3KDZ A;  1YFE A;  2E9F A;  3C8T A;  2O7E A;  2RJS A;  2O7F A;  3NZ4 A;  1DCN A;  1GK2 A;  1TJW A;  2QVE A;  1TJU A;  3NO9 A;  2VD6 A;  1Y2M A;  2QGA B;  3KDY A;  4APB A;  1XWO A;  3TV2 A;  2J91 A;  1T6J A;  3R6V A;  1FUP A;  4C6G A;  5HW2 A;  2OHY A;  2PTS A;  1U16 A;  3R6Q A;  1T6P A;  4NLE A;  1GKJ A;  4CQ5 A;  1TJ7 A;  1YIS A;  1GKM A;  4FLC A;  2PFM A;  4BAA A;  2FUS A;  4APA A;  1FUR A;  1FUQ A;  1C3C A;  1RE5 A;  1J3U A;  3OCF A;  4NSL A;  1C3U A;  1K7W A;  2HVG A;  1EB4 A;  1Q5N A;  4C5U A;  1U15 A;  1B8F A;  3GZH A;  3BHG A;  3GTD A;  4EEI A;  1K62 A;  4V2Q A;  4EFC A;  5F92 A;  1DOF A;  3RRP A;  4C5R A;  2PTQ A;  1JSW A;  4BAB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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