1JSWA

Native l-aspartate ammonia lyase
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
459
structure length
459
Chain Sequence
MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLIKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Amino acid ammonia-lyase
molecule keywords L-ASPARTATE AMMONIA-LYASE
publication title The structure of L-aspartate ammonia-lyase from Escherichia coli.
pubmed doi rcsb
total genus 139
structure length 459
sequence length 459
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.1: Aspartate ammonia-lyase.
pdb deposition date 1997-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1jswA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1jswA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1jswA02
1DOFA 2J91A 2OHYA 3GZHA 4APBA 1TJ7A 4ADLA 2YIIA 4BAAA 2X75A 1FUQA 2NYFA 3CZOA 2QVEA 1I0AA 4HGVA 4V2RA 2PTRA 1GKJA 1GK3A 1T6PA 1HY0A 4C5SA 3TV2A 4NSLA 3C8TA 1T6JA 2O7FA 1EB4A 1W27A 5D6BA 5F91A 2VD6A 1FURA 2NYNA 3KDZA 3UNVA 1Q5NA 4V2QA 1YISA 1GKMA 1C3CA 1K7WA 2O78A 3RD8A 1YFEA 4MX2A 3GTDA 2PTQA 3OCEA 2RJRA 2O7EA 1RE5A 5EYVA 2O7BA 1JSWA 3R6QA 4FLCA 4ADMA 3KDYA 1FUPA 2FUSA 2PTSA 1J3UA 4APAA 1U16A 1Y2MA 4C6GA 4C5UA 3E04A 2E9FA 1TJWA 1B8FA 3RRPA 1K62A 1VDKA 5F92A 1U15A 1C3UA 2O7DA 2QGAB 4EEIA 1GK2A 1YFMA 2HVGA 5EYTA 1TJUA 3BHGA 4C5RA 3R6VA 4EFCA 5HW2A 1AUWA 4NLEA 1DCNA 4BABA 1FUOA 4CQ5A 3OCFA 1XWOA 2RJSA 3NZ4A 1KQ7A 3NO9A 1TJVA 2O6YA 3QBPA 4FFXA 3R6YA 2PFMA 1HY1A
chains in the Genus database with same CATH superfamily
2FENA 1DOFA 2J91A 2OHYA 1Z4QA 3GZHA 4APBA 1TJ7A 4ADLA 5M0IA 2JAUA 2YIIA 4E88A 4BAAA 2X75A 1Q91A 1FUQA 3BWVA 4YIHA 2NYFA 3CZOA 2QVEA 1I0AA 3CRVA 4HGVA 3F4RA 4YIKA 4V2RA 2PTRA 1GKJA 1GK3A 1Z4JA 1T6PA 1XL7A 1HY0A 3U13A 4C5SA 3CI0K 3TV2A 4WNLA 4NSLA 2RCNA 3C8TA 1T6JA 2O7FA 1EB4A 2VL7A 1W27A 5D6BA 3F4SA 5F91A 2VD6A 1IW7D 1FURA 2NYNA 3KDZA 3UNVA 1MH9A 1Q5NA 4V2QA 2FELA 4L6CA 4L6AA 1XLYA 1YISA 4L57A 1GKMA 1C3CA 1K7WA 2O78A 3RD8A 2VSFA 1YFEA 4MX2A 2D28C 2JAOA 3GTDA 1Z4MA 2PTQA 3OCEA 2RJRA 2O7EA 1RE5A 5EYVA 4NFLA 2O7BA 2JAWA 1JSWA 3R6QA 1T9HA 4FLCA 4ADMA 3KDYA 1FUPA 2FUSA 2PTSA 1J3UA 1Z4IA 2YV5A 1Z4KA 4APAA 1XMDA 1U16A 2JARA 3U19A 1Z4PX 1Y2MA 4C6GA 4C5UA 3E04A 2E9FA 1XL8A 1TJWA 1B8FA 3RRPA 1K62A 1VDKA 5F92A 1U15A 1C3UA 4MUMA 2O7DA 2QGAB 4EEIA 1GK2A 2D27A 1YFMA 2HVGA 2I7DA 5EYTA 1TJUA 3BHGA 3CRW1 1XMCA 4C5RA 5H8WA 3R6VA 4EFCA 5HW2A 1U0LA 1AUWA 4NLEA 4IQJM 1DCNA 4BABA 1Q92A 1FUOA 4CQ5A 4A15A 3OCFA 1XWOA 1Z4LA 2RJSA 3NZ4A 5M0JA 1KQ7A 3NO9A 1TJVA 2O6YA 3QBPA 4FFXA 3R6YA 2PFMA 3F4TA 4MWOA 1HY1A
chains in the Genus database with same CATH topology
1DOFA 2J91A 2OHYA 3GZHA 4APBA 1TJ7A 4ADLA 2YIIA 4BAAA 2X75A 1FUQA 2NYFA 3CZOA 2QVEA 1I0AA 4HGVA 4V2RA 2PTRA 1GKJA 1GK3A 1T6PA 1HY0A 4C5SA 3TV2A 4NSLA 3C8TA 1T6JA 2O7FA 1EB4A 1W27A 5D6BA 5F91A 2VD6A 1FURA 2NYNA 3KDZA 3UNVA 1Q5NA 4V2QA 1YISA 1GKMA 1C3CA 1K7WA 2O78A 3RD8A 1YFEA 4MX2A 3GTDA 2PTQA 3OCEA 2RJRA 2O7EA 1RE5A 5EYVA 2O7BA 1JSWA 3R6QA 4FLCA 4ADMA 3KDYA 1FUPA 2FUSA 2PTSA 1J3UA 4APAA 1U16A 1Y2MA 4C6GA 4C5UA 3E04A 2E9FA 1TJWA 1B8FA 3RRPA 1K62A 1VDKA 5F92A 1U15A 1C3UA 2O7DA 2QGAB 4EEIA 1GK2A 1YFMA 2HVGA 5EYTA 1TJUA 3BHGA 4C5RA 3R6VA 4EFCA 5HW2A 1AUWA 4NLEA 1DCNA 4BABA 1FUOA 4CQ5A 3OCFA 1XWOA 2RJSA 3NZ4A 1KQ7A 3NO9A 1TJVA 2O6YA 3QBPA 4FFXA 3R6YA 2PFMA 1HY1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DOF A;  2J91 A;  2OHY A;  3GZH A;  4APB A;  1TJ7 A;  4ADL A;  2YII A;  4BAA A;  2X75 A;  1FUQ A;  2NYF A;  3CZO A;  2QVE A;  1I0A A;  4HGV A;  4V2R A;  2PTR A;  1GKJ A;  1GK3 A;  1T6P A;  1HY0 A;  4C5S A;  3TV2 A;  4NSL A;  3C8T A;  1T6J A;  2O7F A;  1EB4 A;  1W27 A;  5D6B A;  5F91 A;  2VD6 A;  1FUR A;  2NYN A;  3KDZ A;  3UNV A;  1Q5N A;  4V2Q A;  1YIS A;  1GKM A;  1C3C A;  1K7W A;  2O78 A;  3RD8 A;  1YFE A;  4MX2 A;  3GTD A;  2PTQ A;  3OCE A;  2RJR A;  2O7E A;  1RE5 A;  5EYV A;  2O7B A;  1JSW A;  3R6Q A;  4FLC A;  4ADM A;  3KDY A;  1FUP A;  2FUS A;  2PTS A;  1J3U A;  4APA A;  1U16 A;  1Y2M A;  4C6G A;  4C5U A;  3E04 A;  2E9F A;  1TJW A;  1B8F A;  3RRP A;  1K62 A;  1VDK A;  5F92 A;  1U15 A;  1C3U A;  2O7D A;  2QGA B;  4EEI A;  1GK2 A;  1YFM A;  2HVG A;  5EYT A;  1TJU A;  3BHG A;  4C5R A;  3R6V A;  4EFC A;  5HW2 A;  1AUW A;  4NLE A;  1DCN A;  4BAB A;  1FUO A;  4CQ5 A;  3OCF A;  1XWO A;  2RJS A;  3NZ4 A;  1KQ7 A;  3NO9 A;  1TJV A;  2O6Y A;  3QBP A;  4FFX A;  3R6Y A;  2PFM A;  1HY1 A; 
#chains in the Genus database with same CATH topology
 2FEN A;  1DOF A;  2J91 A;  2OHY A;  1Z4Q A;  3GZH A;  4APB A;  1TJ7 A;  4ADL A;  5M0I A;  2JAU A;  2YII A;  4E88 A;  4BAA A;  2X75 A;  1Q91 A;  1FUQ A;  3BWV A;  4YIH A;  2NYF A;  3CZO A;  2QVE A;  1I0A A;  3CRV A;  4HGV A;  3F4R A;  4YIK A;  4V2R A;  2PTR A;  1GKJ A;  1GK3 A;  1Z4J A;  1T6P A;  1XL7 A;  1HY0 A;  3U13 A;  4C5S A;  3CI0 K;  3TV2 A;  4WNL A;  4NSL A;  2RCN A;  3C8T A;  1T6J A;  2O7F A;  1EB4 A;  2VL7 A;  1W27 A;  5D6B A;  3F4S A;  5F91 A;  2VD6 A;  1IW7 D;  1FUR A;  2NYN A;  3KDZ A;  3UNV A;  1MH9 A;  1Q5N A;  4V2Q A;  2FEL A;  4L6C A;  4L6A A;  1XLY A;  1YIS A;  4L57 A;  1GKM A;  1C3C A;  1K7W A;  2O78 A;  3RD8 A;  2VSF A;  1YFE A;  4MX2 A;  2D28 C;  2JAO A;  3GTD A;  1Z4M A;  2PTQ A;  3OCE A;  2RJR A;  2O7E A;  1RE5 A;  5EYV A;  4NFL A;  2O7B A;  2JAW A;  1JSW A;  3R6Q A;  1T9H A;  4FLC A;  4ADM A;  3KDY A;  1FUP A;  2FUS A;  2PTS A;  1J3U A;  1Z4I A;  2YV5 A;  1Z4K A;  4APA A;  1XMD A;  1U16 A;  2JAR A;  3U19 A;  1Z4P X;  1Y2M A;  4C6G A;  4C5U A;  3E04 A;  2E9F A;  1XL8 A;  1TJW A;  1B8F A;  3RRP A;  1K62 A;  1VDK A;  5F92 A;  1U15 A;  1C3U A;  4MUM A;  2O7D A;  2QGA B;  4EEI A;  1GK2 A;  2D27 A;  1YFM A;  2HVG A;  2I7D A;  5EYT A;  1TJU A;  3BHG A;  3CRW 1;  1XMC A;  4C5R A;  5H8W A;  3R6V A;  4EFC A;  5HW2 A;  1U0L A;  1AUW A;  4NLE A;  4IQJ M;  1DCN A;  4BAB A;  1Q92 A;  1FUO A;  4CQ5 A;  4A15 A;  3OCF A;  1XWO A;  1Z4L A;  2RJS A;  3NZ4 A;  5M0J A;  1KQ7 A;  3NO9 A;  1TJV A;  2O6Y A;  3QBP A;  4FFX A;  3R6Y A;  2PFM A;  3F4T A;  4MWO A;  1HY1 A; 
#chains in the Genus database with same CATH homology
 1DOF A;  2J91 A;  2OHY A;  3GZH A;  4APB A;  1TJ7 A;  4ADL A;  2YII A;  4BAA A;  2X75 A;  1FUQ A;  2NYF A;  3CZO A;  2QVE A;  1I0A A;  4HGV A;  4V2R A;  2PTR A;  1GKJ A;  1GK3 A;  1T6P A;  1HY0 A;  4C5S A;  3TV2 A;  4NSL A;  3C8T A;  1T6J A;  2O7F A;  1EB4 A;  1W27 A;  5D6B A;  5F91 A;  2VD6 A;  1FUR A;  2NYN A;  3KDZ A;  3UNV A;  1Q5N A;  4V2Q A;  1YIS A;  1GKM A;  1C3C A;  1K7W A;  2O78 A;  3RD8 A;  1YFE A;  4MX2 A;  3GTD A;  2PTQ A;  3OCE A;  2RJR A;  2O7E A;  1RE5 A;  5EYV A;  2O7B A;  1JSW A;  3R6Q A;  4FLC A;  4ADM A;  3KDY A;  1FUP A;  2FUS A;  2PTS A;  1J3U A;  4APA A;  1U16 A;  1Y2M A;  4C6G A;  4C5U A;  3E04 A;  2E9F A;  1TJW A;  1B8F A;  3RRP A;  1K62 A;  1VDK A;  5F92 A;  1U15 A;  1C3U A;  2O7D A;  2QGA B;  4EEI A;  1GK2 A;  1YFM A;  2HVG A;  5EYT A;  1TJU A;  3BHG A;  4C5R A;  3R6V A;  4EFC A;  5HW2 A;  1AUW A;  4NLE A;  1DCN A;  4BAB A;  1FUO A;  4CQ5 A;  3OCF A;  1XWO A;  2RJS A;  3NZ4 A;  1KQ7 A;  3NO9 A;  1TJV A;  2O6Y A;  3QBP A;  4FFX A;  3R6Y A;  2PFM A;  1HY1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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