1JSWA

Native l-aspartate ammonia lyase
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
459
structure length
459
Chain Sequence
MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLIKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of L-aspartate ammonia-lyase from Escherichia coli.
pubmed doi rcsb
molecule tags Amino acid ammonia-lyase
molecule keywords L-ASPARTATE AMMONIA-LYASE
total genus 139
structure length 459
sequence length 459
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.1: Aspartate ammonia-lyase.
pdb deposition date 1997-02-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1jswA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1jswA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1jswA02
1YFEA 2J91A 2PTRA 3GTDA 1U16A 4NSLA 1YFMA 1FUQA 1TJ7A 2PFMA 4BAAA 1U15A 4C5UA 1Q5NA 5EYTA 4CQ5A 1DCNA 4FLCA 1GK3A 3NO9A 3RD8A 5F92A 2O7DA 3E04A 1FUOA 3C8TA 3GZHA 3RRPA 5HW2A 3OCEA 3KDYA 3R6QA 4NLEA 2FUSA 1K62A 1TJWA 4C5RA 1VDKA 1W27A 1TJUA 1B8FA 1T6PA 2OHYA 1FURA 1HY1A 1C3UA 3R6VA 5D6BA 4EEIA 4EFCA 4ADMA 2O7EA 1J3UA 1DOFA 4BABA 1YISA 1XWOA 1AUWA 2QGAB 3R6YA 5EYVA 1KQ7A 2PTSA 1GKJA 1Y2MA 2HVGA 2O7FA 4FFXA 4C6GA 2QVEA 3UNVA 4APAA 3CZOA 2YIIA 2X75A 4ADLA 2RJRA 1T6JA 3TV2A 3OCFA 1TJVA 2O78A 1RE5A 3NZ4A 2PTQA 1K7WA 4V2RA 2NYFA 4MX2A 4C5SA 1FUPA 2E9FA 4APBA 1GKMA 1C3CA 2O7BA 1GK2A 3QBPA 1JSWA 1HY0A 4V2QA 4HGVA 5F91A 2RJSA 1I0AA 3BHGA 2O6YA 3KDZA 2VD6A 2NYNA 1EB4A
chains in the Genus database with same CATH superfamily
1YFEA 2J91A 2PTRA 3F4TA 3GTDA 1U16A 4NSLA 1YFMA 1FUQA 1TJ7A 1Z4LA 2PFMA 4BAAA 3F4RA 2VL7A 3CI0K 1U15A 4C5UA 1Q5NA 1U0LA 5EYTA 4CQ5A 1DCNA 4FLCA 1GK3A 1Z4PX 1Q92A 3NO9A 3RD8A 3U13A 5F92A 2O7DA 2FELA 3E04A 1FUOA 3C8TA 4WNLA 3GZHA 3RRPA 5HW2A 3OCEA 3KDYA 5H8WA 3R6QA 4NLEA 2FUSA 2JAUA 4A15A 2FENA 1K62A 4L6AA 1TJWA 2VSFA 1Q91A 1XMDA 4C5RA 1VDKA 1Z4QA 1XMCA 1W27A 3U19A 1TJUA 2D27A 1B8FA 4MUMA 1T6PA 2OHYA 1FURA 1HY1A 1C3UA 1Z4JA 3R6VA 1Z4KA 4YIKA 5D6BA 4EEIA 2D28C 4EFCA 3F4SA 4L6CA 1XLYA 2JARA 1XL8A 4E88A 4ADMA 2YV5A 4NFLA 2O7EA 4IQJM 1T9HA 4MWOA 1J3UA 2RCNA 1DOFA 4BABA 1YISA 1XWOA 3BWVA 1AUWA 2QGAB 3R6YA 1XL7A 5EYVA 1KQ7A 2PTSA 1GKJA 1Y2MA 2HVGA 2O7FA 4FFXA 4C6GA 2QVEA 1MH9A 3UNVA 4APAA 3CZOA 2YIIA 2X75A 4ADLA 2RJRA 1T6JA 3TV2A 3OCFA 1TJVA 2O78A 3CRVA 1RE5A 5M0IA 3NZ4A 2PTQA 1K7WA 4V2RA 2NYFA 2JAOA 4MX2A 4C5SA 2JAWA 1FUPA 2E9FA 2I7DA 4APBA 1GKMA 5M0JA 1C3CA 2O7BA 1GK2A 1Z4IA 3QBPA 1Z4MA 1JSWA 1HY0A 4L57A 4V2QA 4HGVA 5F91A 2RJSA 3CRW1 1IW7D 1I0AA 3BHGA 4YIHA 2O6YA 3KDZA 2VD6A 2NYNA 1EB4A
chains in the Genus database with same CATH topology
1YFEA 2J91A 2PTRA 3GTDA 1U16A 4NSLA 1YFMA 1FUQA 1TJ7A 2PFMA 4BAAA 1U15A 4C5UA 1Q5NA 5EYTA 4CQ5A 1DCNA 4FLCA 1GK3A 3NO9A 3RD8A 5F92A 2O7DA 3E04A 1FUOA 3C8TA 3GZHA 3RRPA 5HW2A 3OCEA 3KDYA 3R6QA 4NLEA 2FUSA 1K62A 1TJWA 4C5RA 1VDKA 1W27A 1TJUA 1B8FA 1T6PA 2OHYA 1FURA 1HY1A 1C3UA 3R6VA 5D6BA 4EEIA 4EFCA 4ADMA 2O7EA 1J3UA 1DOFA 4BABA 1YISA 1XWOA 1AUWA 2QGAB 3R6YA 5EYVA 1KQ7A 2PTSA 1GKJA 1Y2MA 2HVGA 2O7FA 4FFXA 4C6GA 2QVEA 3UNVA 4APAA 3CZOA 2YIIA 2X75A 4ADLA 2RJRA 1T6JA 3TV2A 3OCFA 1TJVA 2O78A 1RE5A 3NZ4A 2PTQA 1K7WA 4V2RA 2NYFA 4MX2A 4C5SA 1FUPA 2E9FA 4APBA 1GKMA 1C3CA 2O7BA 1GK2A 3QBPA 1JSWA 1HY0A 4V2QA 4HGVA 5F91A 2RJSA 1I0AA 3BHGA 2O6YA 3KDZA 2VD6A 2NYNA 1EB4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YFE A;  2J91 A;  2PTR A;  3GTD A;  1U16 A;  4NSL A;  1YFM A;  1FUQ A;  1TJ7 A;  2PFM A;  4BAA A;  1U15 A;  4C5U A;  1Q5N A;  5EYT A;  4CQ5 A;  1DCN A;  4FLC A;  1GK3 A;  3NO9 A;  3RD8 A;  5F92 A;  2O7D A;  3E04 A;  1FUO A;  3C8T A;  3GZH A;  3RRP A;  5HW2 A;  3OCE A;  3KDY A;  3R6Q A;  4NLE A;  2FUS A;  1K62 A;  1TJW A;  4C5R A;  1VDK A;  1W27 A;  1TJU A;  1B8F A;  1T6P A;  2OHY A;  1FUR A;  1HY1 A;  1C3U A;  3R6V A;  5D6B A;  4EEI A;  4EFC A;  4ADM A;  2O7E A;  1J3U A;  1DOF A;  4BAB A;  1YIS A;  1XWO A;  1AUW A;  2QGA B;  3R6Y A;  5EYV A;  1KQ7 A;  2PTS A;  1GKJ A;  1Y2M A;  2HVG A;  2O7F A;  4FFX A;  4C6G A;  2QVE A;  3UNV A;  4APA A;  3CZO A;  2YII A;  2X75 A;  4ADL A;  2RJR A;  1T6J A;  3TV2 A;  3OCF A;  1TJV A;  2O78 A;  1RE5 A;  3NZ4 A;  2PTQ A;  1K7W A;  4V2R A;  2NYF A;  4MX2 A;  4C5S A;  1FUP A;  2E9F A;  4APB A;  1GKM A;  1C3C A;  2O7B A;  1GK2 A;  3QBP A;  1JSW A;  1HY0 A;  4V2Q A;  4HGV A;  5F91 A;  2RJS A;  1I0A A;  3BHG A;  2O6Y A;  3KDZ A;  2VD6 A;  2NYN A;  1EB4 A; 
#chains in the Genus database with same CATH topology
 1YFE A;  2J91 A;  2PTR A;  3F4T A;  3GTD A;  1U16 A;  4NSL A;  1YFM A;  1FUQ A;  1TJ7 A;  1Z4L A;  2PFM A;  4BAA A;  3F4R A;  2VL7 A;  3CI0 K;  1U15 A;  4C5U A;  1Q5N A;  1U0L A;  5EYT A;  4CQ5 A;  1DCN A;  4FLC A;  1GK3 A;  1Z4P X;  1Q92 A;  3NO9 A;  3RD8 A;  3U13 A;  5F92 A;  2O7D A;  2FEL A;  3E04 A;  1FUO A;  3C8T A;  4WNL A;  3GZH A;  3RRP A;  5HW2 A;  3OCE A;  3KDY A;  5H8W A;  3R6Q A;  4NLE A;  2FUS A;  2JAU A;  4A15 A;  2FEN A;  1K62 A;  4L6A A;  1TJW A;  2VSF A;  1Q91 A;  1XMD A;  4C5R A;  1VDK A;  1Z4Q A;  1XMC A;  1W27 A;  3U19 A;  1TJU A;  2D27 A;  1B8F A;  4MUM A;  1T6P A;  2OHY A;  1FUR A;  1HY1 A;  1C3U A;  1Z4J A;  3R6V A;  1Z4K A;  4YIK A;  5D6B A;  4EEI A;  2D28 C;  4EFC A;  3F4S A;  4L6C A;  1XLY A;  2JAR A;  1XL8 A;  4E88 A;  4ADM A;  2YV5 A;  4NFL A;  2O7E A;  4IQJ M;  1T9H A;  4MWO A;  1J3U A;  2RCN A;  1DOF A;  4BAB A;  1YIS A;  1XWO A;  3BWV A;  1AUW A;  2QGA B;  3R6Y A;  1XL7 A;  5EYV A;  1KQ7 A;  2PTS A;  1GKJ A;  1Y2M A;  2HVG A;  2O7F A;  4FFX A;  4C6G A;  2QVE A;  1MH9 A;  3UNV A;  4APA A;  3CZO A;  2YII A;  2X75 A;  4ADL A;  2RJR A;  1T6J A;  3TV2 A;  3OCF A;  1TJV A;  2O78 A;  3CRV A;  1RE5 A;  5M0I A;  3NZ4 A;  2PTQ A;  1K7W A;  4V2R A;  2NYF A;  2JAO A;  4MX2 A;  4C5S A;  2JAW A;  1FUP A;  2E9F A;  2I7D A;  4APB A;  1GKM A;  5M0J A;  1C3C A;  2O7B A;  1GK2 A;  1Z4I A;  3QBP A;  1Z4M A;  1JSW A;  1HY0 A;  4L57 A;  4V2Q A;  4HGV A;  5F91 A;  2RJS A;  3CRW 1;  1IW7 D;  1I0A A;  3BHG A;  4YIH A;  2O6Y A;  3KDZ A;  2VD6 A;  2NYN A;  1EB4 A; 
#chains in the Genus database with same CATH homology
 1YFE A;  2J91 A;  2PTR A;  3GTD A;  1U16 A;  4NSL A;  1YFM A;  1FUQ A;  1TJ7 A;  2PFM A;  4BAA A;  1U15 A;  4C5U A;  1Q5N A;  5EYT A;  4CQ5 A;  1DCN A;  4FLC A;  1GK3 A;  3NO9 A;  3RD8 A;  5F92 A;  2O7D A;  3E04 A;  1FUO A;  3C8T A;  3GZH A;  3RRP A;  5HW2 A;  3OCE A;  3KDY A;  3R6Q A;  4NLE A;  2FUS A;  1K62 A;  1TJW A;  4C5R A;  1VDK A;  1W27 A;  1TJU A;  1B8F A;  1T6P A;  2OHY A;  1FUR A;  1HY1 A;  1C3U A;  3R6V A;  5D6B A;  4EEI A;  4EFC A;  4ADM A;  2O7E A;  1J3U A;  1DOF A;  4BAB A;  1YIS A;  1XWO A;  1AUW A;  2QGA B;  3R6Y A;  5EYV A;  1KQ7 A;  2PTS A;  1GKJ A;  1Y2M A;  2HVG A;  2O7F A;  4FFX A;  4C6G A;  2QVE A;  3UNV A;  4APA A;  3CZO A;  2YII A;  2X75 A;  4ADL A;  2RJR A;  1T6J A;  3TV2 A;  3OCF A;  1TJV A;  2O78 A;  1RE5 A;  3NZ4 A;  2PTQ A;  1K7W A;  4V2R A;  2NYF A;  4MX2 A;  4C5S A;  1FUP A;  2E9F A;  4APB A;  1GKM A;  1C3C A;  2O7B A;  1GK2 A;  3QBP A;  1JSW A;  1HY0 A;  4V2Q A;  4HGV A;  5F91 A;  2RJS A;  1I0A A;  3BHG A;  2O6Y A;  3KDZ A;  2VD6 A;  2NYN A;  1EB4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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