2PFMA

Crystal structure of adenylosuccinate lyase (purb) from bacillus anthracis
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
434
structure length
434
Chain Sequence
ISRYTRPEMGAIWTEENKFKAWLEVEILACEAWAELGDIPKEDVKKIREHASFDIDRIYEIEKETRHDVVAFTRAVSETPALGEERKWVHYGLTSTDVVDTALSYILKQANEIILKDLENFVSILANKAKEHKYTIMMGRTHGVHAEPTTFGLKLGLWYEEMKRNVERFKQAANTVRVGKLSGAVGTYANIDPFVEKYVCENLGLEAAPISTQTLQRDRHAHYMSTLALIATSIEKMAVEIRGLQKSETREVEEAFAKGQKGSSAMPHKRNPIGSENMTGLARVIRGYMMTAYENVPLWHERDISHSSAERVILPDATIALNYMLNRFGNIVKNLTVYPENMKRNMTRTYGLIYSQRVMLTLIDKGMVREEAYDIVQPKAMEAWETQVQFKELVEADERITSKLTQEEINECFNYEHHMQHVDTIFERLGLNEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Adenylosuccinate lyase
publication title Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis
rcsb
source organism Bacillus anthracis
total genus 175
structure length 434
sequence length 434
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2007-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 2pfmA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2pfmA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2pfmA02
1DOFA 1FUOA 2PTSA 1GK3A 4C5RA 4NSLA 1GKJA 2NYFA 2NYNA 1T6JA 4APAA 3GZHA 2QGAB 1B8FA 1U15A 4C5UA 1FUQA 4BABA 1GK2A 2HVGA 1YISA 1K62A 3OCEA 2J91A 2O6YA 1TJUA 1Q5NA 4C5SA 1Y2MA 3NZ4A 2O78A 1C3UA 3QBPA 4EEIA 2RJSA 1YFMA 1J3UA 4ADMA 4APBA 1T6PA 1FURA 2RJRA 2E9FA 1KQ7A 4FLCA 1YFEA 1XWOA 3BHGA 4C6GA 4CQ5A 1RE5A 3KDZA 1FUPA 4V2QA 3R6YA 3C8TA 3TV2A 4MX2A 1I0AA 1TJWA 2QVEA 2PTRA 3OCFA 1VDKA 1C3CA 3R6QA 5EYVA 1HY0A 4FFXA 1TJVA 1AUWA 4HGVA 5HW2A 2O7DA 2X75A 1GKMA 1HY1A 5EYTA 1TJ7A 5D6BA 1JSWA 2O7BA 1W27A 3NO9A 2YIIA 4V2RA 1K7WA 2PFMA 3RRPA 4EFCA 1U16A 2PTQA 3GTDA 5F92A 2OHYA 2O7EA 4BAAA 2FUSA 5F91A 2VD6A 4NLEA 2O7FA 3UNVA 3RD8A 1DCNA 3E04A 1EB4A 4ADLA 3CZOA 3KDYA 3R6VA
chains in the Genus database with same CATH superfamily
4L57A 1DOFA 1IW7D 4L6AA 1FUOA 2PTSA 1MH9A 1GK3A 4C5RA 1Z4JA 4NSLA 1GKJA 2NYFA 2NYNA 1T6JA 1Z4LA 4NFLA 2FELA 4APAA 1U0LA 3GZHA 2QGAB 1B8FA 1U15A 4C5UA 1FUQA 5M0JA 4BABA 1GK2A 2D28C 2HVGA 1YISA 3U13A 1K62A 3OCEA 2J91A 2O6YA 2VL7A 1TJUA 1Q5NA 1XMCA 4C5SA 1Y2MA 3NZ4A 2O78A 1C3UA 3CI0K 4A15A 3QBPA 4EEIA 2RJSA 1YFMA 4WNLA 1EB4A 1J3UA 4ADMA 4YIHA 4APBA 1T6PA 1FURA 2RJRA 2E9FA 1KQ7A 4FLCA 1YFEA 1XWOA 3BHGA 1Q91A 4C6GA 4CQ5A 1RE5A 3KDZA 1FUPA 4V2QA 3R6YA 3C8TA 2JAUA 4MX2A 3TV2A 1I0AA 1TJWA 2QVEA 2PTRA 4YIKA 3OCFA 1VDKA 1C3CA 1T9HA 3CRW1 3R6QA 5M0IA 3BWVA 5EYVA 1HY0A 2JAWA 1XMDA 4FFXA 1TJVA 1AUWA 4HGVA 5HW2A 2O7DA 2X75A 1HY1A 1GKMA 4L6CA 1TJ7A 5EYTA 5D6BA 1JSWA 1Z4QA 2RCNA 1XL8A 2O7BA 1W27A 3NO9A 4MWOA 2YIIA 2YV5A 2FENA 1Z4KA 1Z4IA 4V2RA 1K7WA 1XLYA 2PFMA 2VSFA 3RRPA 4EFCA 1Z4MA 1U16A 2JARA 3F4RA 5H8WA 2PTQA 3GTDA 5F92A 2OHYA 2O7EA 4MUMA 4BAAA 2FUSA 5F91A 1Q92A 4IQJM 2VD6A 3U19A 4NLEA 4E88A 2O7FA 3UNVA 2JAOA 3RD8A 3F4TA 2D27A 1DCNA 2I7DA 3CRVA 1XL7A 3E04A 1Z4PX 3F4SA 4ADLA 3CZOA 3KDYA 3R6VA
chains in the Genus database with same CATH topology
1DOFA 1FUOA 2PTSA 1GK3A 4C5RA 4NSLA 1GKJA 2NYFA 2NYNA 1T6JA 4APAA 3GZHA 2QGAB 1B8FA 1U15A 4C5UA 1FUQA 4BABA 1GK2A 2HVGA 1YISA 1K62A 3OCEA 2J91A 2O6YA 1TJUA 1Q5NA 4C5SA 1Y2MA 3NZ4A 2O78A 1C3UA 3QBPA 4EEIA 2RJSA 1YFMA 1J3UA 4ADMA 4APBA 1T6PA 1FURA 2RJRA 2E9FA 1KQ7A 4FLCA 1YFEA 1XWOA 3BHGA 4C6GA 4CQ5A 1RE5A 3KDZA 1FUPA 4V2QA 3R6YA 3C8TA 3TV2A 4MX2A 1I0AA 1TJWA 2QVEA 2PTRA 3OCFA 1VDKA 1C3CA 3R6QA 5EYVA 1HY0A 4FFXA 1TJVA 1AUWA 4HGVA 5HW2A 2O7DA 2X75A 1GKMA 1HY1A 5EYTA 1TJ7A 5D6BA 1JSWA 2O7BA 1W27A 3NO9A 2YIIA 4V2RA 1K7WA 2PFMA 3RRPA 4EFCA 1U16A 2PTQA 3GTDA 5F92A 2OHYA 2O7EA 4BAAA 2FUSA 5F91A 2VD6A 4NLEA 2O7FA 3UNVA 3RD8A 1DCNA 3E04A 1EB4A 4ADLA 3CZOA 3KDYA 3R6VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DOF A;  1FUO A;  2PTS A;  1GK3 A;  4C5R A;  4NSL A;  1GKJ A;  2NYF A;  2NYN A;  1T6J A;  4APA A;  3GZH A;  2QGA B;  1B8F A;  1U15 A;  4C5U A;  1FUQ A;  4BAB A;  1GK2 A;  2HVG A;  1YIS A;  1K62 A;  3OCE A;  2J91 A;  2O6Y A;  1TJU A;  1Q5N A;  4C5S A;  1Y2M A;  3NZ4 A;  2O78 A;  1C3U A;  3QBP A;  4EEI A;  2RJS A;  1YFM A;  1J3U A;  4ADM A;  4APB A;  1T6P A;  1FUR A;  2RJR A;  2E9F A;  1KQ7 A;  4FLC A;  1YFE A;  1XWO A;  3BHG A;  4C6G A;  4CQ5 A;  1RE5 A;  3KDZ A;  1FUP A;  4V2Q A;  3R6Y A;  3C8T A;  3TV2 A;  4MX2 A;  1I0A A;  1TJW A;  2QVE A;  2PTR A;  3OCF A;  1VDK A;  1C3C A;  3R6Q A;  5EYV A;  1HY0 A;  4FFX A;  1TJV A;  1AUW A;  4HGV A;  5HW2 A;  2O7D A;  2X75 A;  1GKM A;  1HY1 A;  5EYT A;  1TJ7 A;  5D6B A;  1JSW A;  2O7B A;  1W27 A;  3NO9 A;  2YII A;  4V2R A;  1K7W A;  2PFM A;  3RRP A;  4EFC A;  1U16 A;  2PTQ A;  3GTD A;  5F92 A;  2OHY A;  2O7E A;  4BAA A;  2FUS A;  5F91 A;  2VD6 A;  4NLE A;  2O7F A;  3UNV A;  3RD8 A;  1DCN A;  3E04 A;  1EB4 A;  4ADL A;  3CZO A;  3KDY A;  3R6V A; 
#chains in the Genus database with same CATH topology
 4L57 A;  1DOF A;  1IW7 D;  4L6A A;  1FUO A;  2PTS A;  1MH9 A;  1GK3 A;  4C5R A;  1Z4J A;  4NSL A;  1GKJ A;  2NYF A;  2NYN A;  1T6J A;  1Z4L A;  4NFL A;  2FEL A;  4APA A;  1U0L A;  3GZH A;  2QGA B;  1B8F A;  1U15 A;  4C5U A;  1FUQ A;  5M0J A;  4BAB A;  1GK2 A;  2D28 C;  2HVG A;  1YIS A;  3U13 A;  1K62 A;  3OCE A;  2J91 A;  2O6Y A;  2VL7 A;  1TJU A;  1Q5N A;  1XMC A;  4C5S A;  1Y2M A;  3NZ4 A;  2O78 A;  1C3U A;  3CI0 K;  4A15 A;  3QBP A;  4EEI A;  2RJS A;  1YFM A;  4WNL A;  1EB4 A;  1J3U A;  4ADM A;  4YIH A;  4APB A;  1T6P A;  1FUR A;  2RJR A;  2E9F A;  1KQ7 A;  4FLC A;  1YFE A;  1XWO A;  3BHG A;  1Q91 A;  4C6G A;  4CQ5 A;  1RE5 A;  3KDZ A;  1FUP A;  4V2Q A;  3R6Y A;  3C8T A;  2JAU A;  4MX2 A;  3TV2 A;  1I0A A;  1TJW A;  2QVE A;  2PTR A;  4YIK A;  3OCF A;  1VDK A;  1C3C A;  1T9H A;  3CRW 1;  3R6Q A;  5M0I A;  3BWV A;  5EYV A;  1HY0 A;  2JAW A;  1XMD A;  4FFX A;  1TJV A;  1AUW A;  4HGV A;  5HW2 A;  2O7D A;  2X75 A;  1HY1 A;  1GKM A;  4L6C A;  1TJ7 A;  5EYT A;  5D6B A;  1JSW A;  1Z4Q A;  2RCN A;  1XL8 A;  2O7B A;  1W27 A;  3NO9 A;  4MWO A;  2YII A;  2YV5 A;  2FEN A;  1Z4K A;  1Z4I A;  4V2R A;  1K7W A;  1XLY A;  2PFM A;  2VSF A;  3RRP A;  4EFC A;  1Z4M A;  1U16 A;  2JAR A;  3F4R A;  5H8W A;  2PTQ A;  3GTD A;  5F92 A;  2OHY A;  2O7E A;  4MUM A;  4BAA A;  2FUS A;  5F91 A;  1Q92 A;  4IQJ M;  2VD6 A;  3U19 A;  4NLE A;  4E88 A;  2O7F A;  3UNV A;  2JAO A;  3RD8 A;  3F4T A;  2D27 A;  1DCN A;  2I7D A;  3CRV A;  1XL7 A;  3E04 A;  1Z4P X;  3F4S A;  4ADL A;  3CZO A;  3KDY A;  3R6V A; 
#chains in the Genus database with same CATH homology
 1DOF A;  1FUO A;  2PTS A;  1GK3 A;  4C5R A;  4NSL A;  1GKJ A;  2NYF A;  2NYN A;  1T6J A;  4APA A;  3GZH A;  2QGA B;  1B8F A;  1U15 A;  4C5U A;  1FUQ A;  4BAB A;  1GK2 A;  2HVG A;  1YIS A;  1K62 A;  3OCE A;  2J91 A;  2O6Y A;  1TJU A;  1Q5N A;  4C5S A;  1Y2M A;  3NZ4 A;  2O78 A;  1C3U A;  3QBP A;  4EEI A;  2RJS A;  1YFM A;  1J3U A;  4ADM A;  4APB A;  1T6P A;  1FUR A;  2RJR A;  2E9F A;  1KQ7 A;  4FLC A;  1YFE A;  1XWO A;  3BHG A;  4C6G A;  4CQ5 A;  1RE5 A;  3KDZ A;  1FUP A;  4V2Q A;  3R6Y A;  3C8T A;  3TV2 A;  4MX2 A;  1I0A A;  1TJW A;  2QVE A;  2PTR A;  3OCF A;  1VDK A;  1C3C A;  3R6Q A;  5EYV A;  1HY0 A;  4FFX A;  1TJV A;  1AUW A;  4HGV A;  5HW2 A;  2O7D A;  2X75 A;  1GKM A;  1HY1 A;  5EYT A;  1TJ7 A;  5D6B A;  1JSW A;  2O7B A;  1W27 A;  3NO9 A;  2YII A;  4V2R A;  1K7W A;  2PFM A;  3RRP A;  4EFC A;  1U16 A;  2PTQ A;  3GTD A;  5F92 A;  2OHY A;  2O7E A;  4BAA A;  2FUS A;  5F91 A;  2VD6 A;  4NLE A;  2O7F A;  3UNV A;  3RD8 A;  1DCN A;  3E04 A;  1EB4 A;  4ADL A;  3CZO A;  3KDY A;  3R6V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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