1GKJA

Histidine ammonia-lyase (hal) mutant y280f from pseudomonas putida
Total Genus 203
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
203
sequence length
507
structure length
506
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPFSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HISTIDINE AMMONIA-LYASE
publication title Structures of Two Histidine Ammonia-Lyase Modifications and Implications for the Catalytic Mechanism
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
total genus 203
structure length 506
sequence length 507
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gkjA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gkjA02
1I0AA 1DOFA 2J91A 3GTDA 4BAAA 1YFEA 1FURA 3NO9A 2FUSA 4NLEA 1YISA 3RRPA 4EEIA 4NSLA 3BHGA 1HY0A 4ADLA 2O6YA 1GK3A 1K7WA 2X75A 5D6BA 4C5UA 1T6PA 1TJWA 1U16A 4APAA 2O78A 2PTRA 4HGVA 4CQ5A 2PTQA 1YFMA 2VD6A 4C6GA 1TJ7A 2YIIA 4BABA 1KQ7A 3QBPA 4V2RA 1DCNA 1T6JA 1Y2MA 3KDZA 3R6VA 2NYNA 1TJVA 1FUOA 1GKJA 3CZOA 1C3CA 3E04A 3UNVA 3RD8A 2QVEA 4V2QA 4C5RA 3OCEA 1FUPA 3R6YA 1J3UA 1B8FA 4ADMA 2O7DA 2O7EA 5HW2A 5EYVA 3TV2A 1FUQA 1TJUA 1AUWA 1GKMA 4FLCA 1W27A 2RJRA 2PTSA 2O7FA 1EB4A 3C8TA 3OCFA 5F91A 4APBA 3NZ4A 1RE5A 4MX2A 3GZHA 2QGAB 2RJSA 4FFXA 1VDKA 2NYFA 5F92A 4EFCA 1HY1A 1C3UA 1GK2A 2PFMA 1JSWA 1XWOA 2O7BA 2E9FA 1Q5NA 1U15A 2HVGA 3R6QA 5EYTA 3KDYA 1K62A 2OHYA 4C5SA
chains in the Genus database with same CATH superfamily
1I0AA 1DOFA 2J91A 3GTDA 4BAAA 1YFEA 1FURA 3NO9A 2FUSA 5H8WA 4NLEA 1YISA 3RRPA 4EEIA 4NSLA 3BHGA 5M0IA 1HY0A 4ADLA 2O6YA 1GK3A 1K7WA 2X75A 5D6BA 4C5UA 4WNLA 1T6PA 1TJWA 1U16A 2FENA 4APAA 2O78A 3CRVA 2PTRA 4HGVA 5M0JA 4CQ5A 2PTQA 1YFMA 2VD6A 4C6GA 1TJ7A 2YIIA 4BABA 2VSFA 1KQ7A 3QBPA 4V2RA 1DCNA 1T6JA 1Y2MA 3KDZA 3R6VA 2FELA 2NYNA 1TJVA 1FUOA 1GKJA 3CZOA 1C3CA 3E04A 3UNVA 3CRW1 3RD8A 2QVEA 4V2QA 2VL7A 4C5RA 3OCEA 1FUPA 3R6YA 1J3UA 1B8FA 4ADMA 2O7DA 2O7EA 5HW2A 5EYVA 3TV2A 1FUQA 1TJUA 1AUWA 1GKMA 4FLCA 4A15A 1W27A 2PTSA 2RJRA 2O7FA 1EB4A 3C8TA 3OCFA 1XLYA 5F91A 1XMCA 4APBA 3NZ4A 1RE5A 4MX2A 3GZHA 2QGAB 2RJSA 4FFXA 1VDKA 2NYFA 5F92A 4EFCA 1HY1A 1XL7A 1C3UA 1GK2A 2PFMA 1JSWA 1XWOA 2O7BA 2E9FA 1Q5NA 1U15A 2HVGA 3R6QA 5EYTA 1XL8A 3KDYA 1K62A 2OHYA 1XMDA 4C5SA
chains in the Genus database with same CATH topology
1I0AA 1DOFA 2J91A 3GTDA 4BAAA 1YFEA 1FURA 3NO9A 2FUSA 4NLEA 1YISA 3RRPA 4EEIA 4NSLA 3BHGA 1HY0A 4ADLA 2O6YA 1GK3A 1K7WA 2X75A 5D6BA 4C5UA 1T6PA 1TJWA 1U16A 4APAA 2O78A 2PTRA 4HGVA 4CQ5A 2PTQA 1YFMA 2VD6A 4C6GA 1TJ7A 2YIIA 4BABA 1KQ7A 3QBPA 4V2RA 1DCNA 1T6JA 1Y2MA 3KDZA 3R6VA 2NYNA 1TJVA 1FUOA 1GKJA 3CZOA 1C3CA 3E04A 3UNVA 3RD8A 2QVEA 4V2QA 4C5RA 3OCEA 1FUPA 3R6YA 1J3UA 1B8FA 4ADMA 2O7DA 2O7EA 5HW2A 5EYVA 3TV2A 1FUQA 1TJUA 1AUWA 1GKMA 4FLCA 1W27A 2RJRA 2PTSA 2O7FA 1EB4A 3C8TA 3OCFA 5F91A 4APBA 3NZ4A 1RE5A 4MX2A 3GZHA 2QGAB 2RJSA 4FFXA 1VDKA 2NYFA 5F92A 4EFCA 1HY1A 1C3UA 1GK2A 2PFMA 1JSWA 1XWOA 2O7BA 2E9FA 1Q5NA 1U15A 2HVGA 3R6QA 5EYTA 3KDYA 1K62A 2OHYA 4C5SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I0A A;  1DOF A;  2J91 A;  3GTD A;  4BAA A;  1YFE A;  1FUR A;  3NO9 A;  2FUS A;  4NLE A;  1YIS A;  3RRP A;  4EEI A;  4NSL A;  3BHG A;  1HY0 A;  4ADL A;  2O6Y A;  1GK3 A;  1K7W A;  2X75 A;  5D6B A;  4C5U A;  1T6P A;  1TJW A;  1U16 A;  4APA A;  2O78 A;  2PTR A;  4HGV A;  4CQ5 A;  2PTQ A;  1YFM A;  2VD6 A;  4C6G A;  1TJ7 A;  2YII A;  4BAB A;  1KQ7 A;  3QBP A;  4V2R A;  1DCN A;  1T6J A;  1Y2M A;  3KDZ A;  3R6V A;  2NYN A;  1TJV A;  1FUO A;  1GKJ A;  3CZO A;  1C3C A;  3E04 A;  3UNV A;  3RD8 A;  2QVE A;  4V2Q A;  4C5R A;  3OCE A;  1FUP A;  3R6Y A;  1J3U A;  1B8F A;  4ADM A;  2O7D A;  2O7E A;  5HW2 A;  5EYV A;  3TV2 A;  1FUQ A;  1TJU A;  1AUW A;  1GKM A;  4FLC A;  1W27 A;  2RJR A;  2PTS A;  2O7F A;  1EB4 A;  3C8T A;  3OCF A;  5F91 A;  4APB A;  3NZ4 A;  1RE5 A;  4MX2 A;  3GZH A;  2QGA B;  2RJS A;  4FFX A;  1VDK A;  2NYF A;  5F92 A;  4EFC A;  1HY1 A;  1C3U A;  1GK2 A;  2PFM A;  1JSW A;  1XWO A;  2O7B A;  2E9F A;  1Q5N A;  1U15 A;  2HVG A;  3R6Q A;  5EYT A;  3KDY A;  1K62 A;  2OHY A;  4C5S A; 
#chains in the Genus database with same CATH topology
 1I0A A;  1DOF A;  2J91 A;  3GTD A;  4BAA A;  1YFE A;  1FUR A;  3NO9 A;  2FUS A;  5H8W A;  4NLE A;  1YIS A;  3RRP A;  4EEI A;  4NSL A;  3BHG A;  5M0I A;  1HY0 A;  4ADL A;  2O6Y A;  1GK3 A;  1K7W A;  2X75 A;  5D6B A;  4C5U A;  4WNL A;  1T6P A;  1TJW A;  1U16 A;  2FEN A;  4APA A;  2O78 A;  3CRV A;  2PTR A;  4HGV A;  5M0J A;  4CQ5 A;  2PTQ A;  1YFM A;  2VD6 A;  4C6G A;  1TJ7 A;  2YII A;  4BAB A;  2VSF A;  1KQ7 A;  3QBP A;  4V2R A;  1DCN A;  1T6J A;  1Y2M A;  3KDZ A;  3R6V A;  2FEL A;  2NYN A;  1TJV A;  1FUO A;  1GKJ A;  3CZO A;  1C3C A;  3E04 A;  3UNV A;  3CRW 1;  3RD8 A;  2QVE A;  4V2Q A;  2VL7 A;  4C5R A;  3OCE A;  1FUP A;  3R6Y A;  1J3U A;  1B8F A;  4ADM A;  2O7D A;  2O7E A;  5HW2 A;  5EYV A;  3TV2 A;  1FUQ A;  1TJU A;  1AUW A;  1GKM A;  4FLC A;  4A15 A;  1W27 A;  2PTS A;  2RJR A;  2O7F A;  1EB4 A;  3C8T A;  3OCF A;  1XLY A;  5F91 A;  1XMC A;  4APB A;  3NZ4 A;  1RE5 A;  4MX2 A;  3GZH A;  2QGA B;  2RJS A;  4FFX A;  1VDK A;  2NYF A;  5F92 A;  4EFC A;  1HY1 A;  1XL7 A;  1C3U A;  1GK2 A;  2PFM A;  1JSW A;  1XWO A;  2O7B A;  2E9F A;  1Q5N A;  1U15 A;  2HVG A;  3R6Q A;  5EYT A;  1XL8 A;  3KDY A;  1K62 A;  2OHY A;  1XMD A;  4C5S A; 
#chains in the Genus database with same CATH homology
 1I0A A;  1DOF A;  2J91 A;  3GTD A;  4BAA A;  1YFE A;  1FUR A;  3NO9 A;  2FUS A;  4NLE A;  1YIS A;  3RRP A;  4EEI A;  4NSL A;  3BHG A;  1HY0 A;  4ADL A;  2O6Y A;  1GK3 A;  1K7W A;  2X75 A;  5D6B A;  4C5U A;  1T6P A;  1TJW A;  1U16 A;  4APA A;  2O78 A;  2PTR A;  4HGV A;  4CQ5 A;  2PTQ A;  1YFM A;  2VD6 A;  4C6G A;  1TJ7 A;  2YII A;  4BAB A;  1KQ7 A;  3QBP A;  4V2R A;  1DCN A;  1T6J A;  1Y2M A;  3KDZ A;  3R6V A;  2NYN A;  1TJV A;  1FUO A;  1GKJ A;  3CZO A;  1C3C A;  3E04 A;  3UNV A;  3RD8 A;  2QVE A;  4V2Q A;  4C5R A;  3OCE A;  1FUP A;  3R6Y A;  1J3U A;  1B8F A;  4ADM A;  2O7D A;  2O7E A;  5HW2 A;  5EYV A;  3TV2 A;  1FUQ A;  1TJU A;  1AUW A;  1GKM A;  4FLC A;  1W27 A;  2RJR A;  2PTS A;  2O7F A;  1EB4 A;  3C8T A;  3OCF A;  5F91 A;  4APB A;  3NZ4 A;  1RE5 A;  4MX2 A;  3GZH A;  2QGA B;  2RJS A;  4FFX A;  1VDK A;  2NYF A;  5F92 A;  4EFC A;  1HY1 A;  1C3U A;  1GK2 A;  2PFM A;  1JSW A;  1XWO A;  2O7B A;  2E9F A;  1Q5N A;  1U15 A;  2HVG A;  3R6Q A;  5EYT A;  3KDY A;  1K62 A;  2OHY A;  4C5S A; 
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