1GKJA

Histidine ammonia-lyase (hal) mutant y280f from pseudomonas putida
Total Genus 203
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
203
sequence length
507
structure length
506
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPFSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Two Histidine Ammonia-Lyase Modifications and Implications for the Catalytic Mechanism
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
molecule keywords HISTIDINE AMMONIA-LYASE
total genus 203
structure length 506
sequence length 507
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gkjA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gkjA02
4ADLA 2PTQA 1DOFA 2O78A 1KQ7A 4APAA 4BABA 5F92A 2FUSA 1T6PA 1HY0A 2O7FA 4C5UA 1U16A 2RJRA 3UNVA 1YFMA 3CZOA 3NZ4A 1DCNA 5EYTA 4NLEA 2O7EA 4C6GA 2YIIA 1YISA 1YFEA 1T6JA 1U15A 1W27A 3R6QA 2PFMA 1TJ7A 5D6BA 4HGVA 4EEIA 5F91A 1FURA 2O6YA 4BAAA 3OCFA 1Y2MA 1AUWA 1TJVA 4NSLA 3C8TA 1GKJA 4V2QA 3GZHA 1RE5A 3QBPA 5EYVA 2OHYA 3KDZA 4C5SA 1TJUA 4V2RA 1GK2A 3OCEA 2PTSA 1GKMA 2QGAB 1I0AA 1K7WA 3TV2A 3E04A 1XWOA 1C3UA 3KDYA 2VD6A 2X75A 1FUQA 2NYFA 1J3UA 4FFXA 4FLCA 1K62A 3BHGA 1B8FA 1JSWA 2QVEA 4CQ5A 3R6YA 2E9FA 2NYNA 2RJSA 4MX2A 3GTDA 1TJWA 1FUPA 2O7BA 3RRPA 3NO9A 4APBA 2HVGA 4ADMA 1C3CA 1VDKA 4C5RA 4EFCA 5HW2A 1FUOA 1Q5NA 3R6VA 1HY1A 1EB4A 1GK3A 2O7DA 2J91A 3RD8A 2PTRA
chains in the Genus database with same CATH superfamily
4ADLA 2PTQA 1DOFA 2VL7A 2O78A 1KQ7A 2FENA 4APAA 4BABA 5F92A 2FUSA 1T6PA 1HY0A 2O7FA 4C5UA 1U16A 2RJRA 3UNVA 1YFMA 2VSFA 3CZOA 3NZ4A 1DCNA 1XL8A 4NLEA 5EYTA 2O7EA 4C6GA 2YIIA 1YISA 1YFEA 1T6JA 1U15A 1W27A 3R6QA 2PFMA 1TJ7A 5D6BA 4HGVA 4EEIA 5F91A 1FURA 2O6YA 1XMDA 3CRVA 4BAAA 3OCFA 1Y2MA 1AUWA 1TJVA 4NSLA 3C8TA 1GKJA 4V2QA 3GZHA 1RE5A 3QBPA 5H8WA 5EYVA 2OHYA 3KDZA 4C5SA 1TJUA 4V2RA 1XL7A 1GK2A 3OCEA 2PTSA 1GKMA 2QGAB 1I0AA 1K7WA 3TV2A 4A15A 3E04A 1XWOA 1C3UA 3KDYA 2VD6A 2X75A 1FUQA 5M0JA 2NYFA 1J3UA 4FFXA 4FLCA 1K62A 3BHGA 1B8FA 1JSWA 2QVEA 4CQ5A 3R6YA 1XLYA 2E9FA 2NYNA 2RJSA 4MX2A 3GTDA 1TJWA 1FUPA 2O7BA 2FELA 3RRPA 3NO9A 4WNLA 4APBA 2HVGA 4ADMA 1C3CA 1VDKA 4C5RA 4EFCA 5M0IA 5HW2A 1FUOA 1Q5NA 3R6VA 1XMCA 1HY1A 1EB4A 1GK3A 2O7DA 2J91A 3CRW1 3RD8A 2PTRA
chains in the Genus database with same CATH topology
4ADLA 2PTQA 1DOFA 2O78A 1KQ7A 4APAA 4BABA 5F92A 2FUSA 1T6PA 1HY0A 2O7FA 4C5UA 1U16A 2RJRA 3UNVA 1YFMA 3CZOA 3NZ4A 1DCNA 5EYTA 4NLEA 2O7EA 4C6GA 2YIIA 1YISA 1YFEA 1T6JA 1U15A 1W27A 3R6QA 2PFMA 1TJ7A 5D6BA 4HGVA 4EEIA 5F91A 1FURA 2O6YA 4BAAA 3OCFA 1Y2MA 1AUWA 1TJVA 4NSLA 3C8TA 1GKJA 4V2QA 3GZHA 1RE5A 3QBPA 5EYVA 2OHYA 3KDZA 4C5SA 1TJUA 4V2RA 1GK2A 3OCEA 2PTSA 1GKMA 2QGAB 1I0AA 1K7WA 3TV2A 3E04A 1XWOA 1C3UA 3KDYA 2VD6A 2X75A 1FUQA 2NYFA 1J3UA 4FFXA 4FLCA 1K62A 3BHGA 1B8FA 1JSWA 2QVEA 4CQ5A 3R6YA 2E9FA 2NYNA 2RJSA 4MX2A 3GTDA 1TJWA 1FUPA 2O7BA 3RRPA 3NO9A 4APBA 2HVGA 4ADMA 1C3CA 1VDKA 4C5RA 4EFCA 5HW2A 1FUOA 1Q5NA 3R6VA 1HY1A 1EB4A 1GK3A 2O7DA 2J91A 3RD8A 2PTRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ADL A;  2PTQ A;  1DOF A;  2O78 A;  1KQ7 A;  4APA A;  4BAB A;  5F92 A;  2FUS A;  1T6P A;  1HY0 A;  2O7F A;  4C5U A;  1U16 A;  2RJR A;  3UNV A;  1YFM A;  3CZO A;  3NZ4 A;  1DCN A;  5EYT A;  4NLE A;  2O7E A;  4C6G A;  2YII A;  1YIS A;  1YFE A;  1T6J A;  1U15 A;  1W27 A;  3R6Q A;  2PFM A;  1TJ7 A;  5D6B A;  4HGV A;  4EEI A;  5F91 A;  1FUR A;  2O6Y A;  4BAA A;  3OCF A;  1Y2M A;  1AUW A;  1TJV A;  4NSL A;  3C8T A;  1GKJ A;  4V2Q A;  3GZH A;  1RE5 A;  3QBP A;  5EYV A;  2OHY A;  3KDZ A;  4C5S A;  1TJU A;  4V2R A;  1GK2 A;  3OCE A;  2PTS A;  1GKM A;  2QGA B;  1I0A A;  1K7W A;  3TV2 A;  3E04 A;  1XWO A;  1C3U A;  3KDY A;  2VD6 A;  2X75 A;  1FUQ A;  2NYF A;  1J3U A;  4FFX A;  4FLC A;  1K62 A;  3BHG A;  1B8F A;  1JSW A;  2QVE A;  4CQ5 A;  3R6Y A;  2E9F A;  2NYN A;  2RJS A;  4MX2 A;  3GTD A;  1TJW A;  1FUP A;  2O7B A;  3RRP A;  3NO9 A;  4APB A;  2HVG A;  4ADM A;  1C3C A;  1VDK A;  4C5R A;  4EFC A;  5HW2 A;  1FUO A;  1Q5N A;  3R6V A;  1HY1 A;  1EB4 A;  1GK3 A;  2O7D A;  2J91 A;  3RD8 A;  2PTR A; 
#chains in the Genus database with same CATH topology
 4ADL A;  2PTQ A;  1DOF A;  2VL7 A;  2O78 A;  1KQ7 A;  2FEN A;  4APA A;  4BAB A;  5F92 A;  2FUS A;  1T6P A;  1HY0 A;  2O7F A;  4C5U A;  1U16 A;  2RJR A;  3UNV A;  1YFM A;  2VSF A;  3CZO A;  3NZ4 A;  1DCN A;  1XL8 A;  4NLE A;  5EYT A;  2O7E A;  4C6G A;  2YII A;  1YIS A;  1YFE A;  1T6J A;  1U15 A;  1W27 A;  3R6Q A;  2PFM A;  1TJ7 A;  5D6B A;  4HGV A;  4EEI A;  5F91 A;  1FUR A;  2O6Y A;  1XMD A;  3CRV A;  4BAA A;  3OCF A;  1Y2M A;  1AUW A;  1TJV A;  4NSL A;  3C8T A;  1GKJ A;  4V2Q A;  3GZH A;  1RE5 A;  3QBP A;  5H8W A;  5EYV A;  2OHY A;  3KDZ A;  4C5S A;  1TJU A;  4V2R A;  1XL7 A;  1GK2 A;  3OCE A;  2PTS A;  1GKM A;  2QGA B;  1I0A A;  1K7W A;  3TV2 A;  4A15 A;  3E04 A;  1XWO A;  1C3U A;  3KDY A;  2VD6 A;  2X75 A;  1FUQ A;  5M0J A;  2NYF A;  1J3U A;  4FFX A;  4FLC A;  1K62 A;  3BHG A;  1B8F A;  1JSW A;  2QVE A;  4CQ5 A;  3R6Y A;  1XLY A;  2E9F A;  2NYN A;  2RJS A;  4MX2 A;  3GTD A;  1TJW A;  1FUP A;  2O7B A;  2FEL A;  3RRP A;  3NO9 A;  4WNL A;  4APB A;  2HVG A;  4ADM A;  1C3C A;  1VDK A;  4C5R A;  4EFC A;  5M0I A;  5HW2 A;  1FUO A;  1Q5N A;  3R6V A;  1XMC A;  1HY1 A;  1EB4 A;  1GK3 A;  2O7D A;  2J91 A;  3CRW 1;  3RD8 A;  2PTR A; 
#chains in the Genus database with same CATH homology
 4ADL A;  2PTQ A;  1DOF A;  2O78 A;  1KQ7 A;  4APA A;  4BAB A;  5F92 A;  2FUS A;  1T6P A;  1HY0 A;  2O7F A;  4C5U A;  1U16 A;  2RJR A;  3UNV A;  1YFM A;  3CZO A;  3NZ4 A;  1DCN A;  5EYT A;  4NLE A;  2O7E A;  4C6G A;  2YII A;  1YIS A;  1YFE A;  1T6J A;  1U15 A;  1W27 A;  3R6Q A;  2PFM A;  1TJ7 A;  5D6B A;  4HGV A;  4EEI A;  5F91 A;  1FUR A;  2O6Y A;  4BAA A;  3OCF A;  1Y2M A;  1AUW A;  1TJV A;  4NSL A;  3C8T A;  1GKJ A;  4V2Q A;  3GZH A;  1RE5 A;  3QBP A;  5EYV A;  2OHY A;  3KDZ A;  4C5S A;  1TJU A;  4V2R A;  1GK2 A;  3OCE A;  2PTS A;  1GKM A;  2QGA B;  1I0A A;  1K7W A;  3TV2 A;  3E04 A;  1XWO A;  1C3U A;  3KDY A;  2VD6 A;  2X75 A;  1FUQ A;  2NYF A;  1J3U A;  4FFX A;  4FLC A;  1K62 A;  3BHG A;  1B8F A;  1JSW A;  2QVE A;  4CQ5 A;  3R6Y A;  2E9F A;  2NYN A;  2RJS A;  4MX2 A;  3GTD A;  1TJW A;  1FUP A;  2O7B A;  3RRP A;  3NO9 A;  4APB A;  2HVG A;  4ADM A;  1C3C A;  1VDK A;  4C5R A;  4EFC A;  5HW2 A;  1FUO A;  1Q5N A;  3R6V A;  1HY1 A;  1EB4 A;  1GK3 A;  2O7D A;  2J91 A;  3RD8 A;  2PTR A; 
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