1TJ7A

Structure determination and refinement at 2.44 a resolution of argininosuccinate lyase from e. coli
Total Genus 177
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
455
structure length
455
Chain Sequence
LWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Argininosuccinate lyase
publication title Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli.
pubmed doi rcsb
molecule tags Lyase
total genus 177
structure length 455
sequence length 455
chains with identical sequence B
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2004-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1tj7A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1tj7A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1tj7A02
4EFCA 2QVEA 2J91A 1T6PA 3GZHA 2O6YA 1Q5NA 4BABA 3KDYA 1K62A 3TV2A 3OCEA 5F91A 1GK2A 1HY1A 4ADLA 4NLEA 4FFXA 1TJWA 3UNVA 4C6GA 1DCNA 5HW2A 1U15A 4CQ5A 2OHYA 4NSLA 3E04A 3BHGA 5EYVA 3R6YA 4ADMA 4EEIA 2NYFA 1DOFA 1U16A 5D6BA 1YISA 1TJ7A 3CZOA 1FUPA 2X75A 1AUWA 1I0AA 4MX2A 3RD8A 2NYNA 4HGVA 1JSWA 2QGAB 4V2RA 1YFMA 1FURA 1VDKA 4V2QA 4C5UA 1J3UA 1HY0A 2O7BA 1W27A 2YIIA 1FUQA 3R6VA 4C5RA 4BAAA 1YFEA 2RJRA 1EB4A 1TJUA 3QBPA 1XWOA 1RE5A 1C3UA 1B8FA 3R6QA 2O7FA 2PTSA 1GKMA 3OCFA 4APAA 1GK3A 3NZ4A 2O78A 3NO9A 2PFMA 3GTDA 2E9FA 2PTQA 5EYTA 2O7EA 1FUOA 1K7WA 2RJSA 1Y2MA 3KDZA 1GKJA 2HVGA 2FUSA 2VD6A 2PTRA 3C8TA 1C3CA 4APBA 3RRPA 2O7DA 4C5SA 1KQ7A 1T6JA 4FLCA 5F92A 1TJVA
chains in the Genus database with same CATH superfamily
4EFCA 2QVEA 2J91A 1T6PA 2YV5A 3GZHA 5H8WA 4YIKA 2O6YA 1Q5NA 1Q92A 2VSFA 4BABA 3KDYA 1K62A 3CI0K 3TV2A 3OCEA 5F91A 4MWOA 1GK2A 1XMDA 1HY1A 2FELA 4ADLA 2FENA 4NLEA 4FFXA 1TJWA 3UNVA 4C6GA 1DCNA 5HW2A 1U15A 4CQ5A 2OHYA 4NSLA 5M0IA 2JAOA 3E04A 3BHGA 5EYVA 3CRVA 4NFLA 3R6YA 4ADMA 4E88A 1Z4MA 4EEIA 2NYFA 1DOFA 1U16A 5D6BA 1YISA 1TJ7A 1XL8A 3CZOA 1FUPA 2X75A 3F4SA 1IW7D 1AUWA 1I0AA 4MX2A 2JARA 1Q91A 3RD8A 2NYNA 4HGVA 1JSWA 2QGAB 3CRW1 4V2RA 1YFMA 1FURA 2JAWA 1VDKA 4V2QA 4C5UA 1J3UA 1HY0A 3F4TA 2O7BA 2D27A 1Z4KA 1W27A 2YIIA 2VL7A 1FUQA 4MUMA 3R6VA 4C5RA 4BAAA 1YFEA 2RJRA 1EB4A 2D28C 2JAUA 1U0LA 1TJUA 5M0JA 3QBPA 1XWOA 1RE5A 1C3UA 4L57A 1B8FA 3R6QA 2O7FA 2PTSA 4YIHA 1GKMA 3OCFA 4APAA 1XL7A 1MH9A 1XLYA 1GK3A 3NZ4A 2O78A 3NO9A 2PFMA 1Z4LA 3GTDA 2E9FA 2PTQA 5EYTA 1T9HA 2O7EA 4A15A 2I7DA 1Z4JA 1Z4QA 4L6CA 1FUOA 1K7WA 4IQJM 4WNLA 2RJSA 1Y2MA 3KDZA 3F4RA 3BWVA 3U13A 1GKJA 1Z4PX 2HVGA 2FUSA 3U19A 1Z4IA 4L6AA 1XMCA 2VD6A 2PTRA 3C8TA 1C3CA 4APBA 2RCNA 3RRPA 2O7DA 4C5SA 1KQ7A 1T6JA 4FLCA 5F92A 1TJVA
chains in the Genus database with same CATH topology
4EFCA 2QVEA 2J91A 1T6PA 3GZHA 2O6YA 1Q5NA 4BABA 3KDYA 1K62A 3TV2A 3OCEA 5F91A 1GK2A 1HY1A 4ADLA 4NLEA 4FFXA 1TJWA 3UNVA 4C6GA 1DCNA 5HW2A 1U15A 4CQ5A 2OHYA 4NSLA 3E04A 3BHGA 5EYVA 3R6YA 4ADMA 4EEIA 2NYFA 1DOFA 1U16A 5D6BA 1YISA 1TJ7A 3CZOA 1FUPA 2X75A 1AUWA 1I0AA 4MX2A 3RD8A 2NYNA 4HGVA 1JSWA 2QGAB 4V2RA 1YFMA 1FURA 1VDKA 4V2QA 4C5UA 1J3UA 1HY0A 2O7BA 1W27A 2YIIA 1FUQA 3R6VA 4C5RA 4BAAA 1YFEA 2RJRA 1EB4A 1TJUA 3QBPA 1XWOA 1RE5A 1C3UA 1B8FA 3R6QA 2O7FA 2PTSA 1GKMA 3OCFA 4APAA 1GK3A 3NZ4A 2O78A 3NO9A 2PFMA 3GTDA 2E9FA 2PTQA 5EYTA 2O7EA 1FUOA 1K7WA 2RJSA 1Y2MA 3KDZA 1GKJA 2HVGA 2FUSA 2VD6A 2PTRA 3C8TA 1C3CA 4APBA 3RRPA 2O7DA 4C5SA 1KQ7A 1T6JA 4FLCA 5F92A 1TJVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EFC A;  2QVE A;  2J91 A;  1T6P A;  3GZH A;  2O6Y A;  1Q5N A;  4BAB A;  3KDY A;  1K62 A;  3TV2 A;  3OCE A;  5F91 A;  1GK2 A;  1HY1 A;  4ADL A;  4NLE A;  4FFX A;  1TJW A;  3UNV A;  4C6G A;  1DCN A;  5HW2 A;  1U15 A;  4CQ5 A;  2OHY A;  4NSL A;  3E04 A;  3BHG A;  5EYV A;  3R6Y A;  4ADM A;  4EEI A;  2NYF A;  1DOF A;  1U16 A;  5D6B A;  1YIS A;  1TJ7 A;  3CZO A;  1FUP A;  2X75 A;  1AUW A;  1I0A A;  4MX2 A;  3RD8 A;  2NYN A;  4HGV A;  1JSW A;  2QGA B;  4V2R A;  1YFM A;  1FUR A;  1VDK A;  4V2Q A;  4C5U A;  1J3U A;  1HY0 A;  2O7B A;  1W27 A;  2YII A;  1FUQ A;  3R6V A;  4C5R A;  4BAA A;  1YFE A;  2RJR A;  1EB4 A;  1TJU A;  3QBP A;  1XWO A;  1RE5 A;  1C3U A;  1B8F A;  3R6Q A;  2O7F A;  2PTS A;  1GKM A;  3OCF A;  4APA A;  1GK3 A;  3NZ4 A;  2O78 A;  3NO9 A;  2PFM A;  3GTD A;  2E9F A;  2PTQ A;  5EYT A;  2O7E A;  1FUO A;  1K7W A;  2RJS A;  1Y2M A;  3KDZ A;  1GKJ A;  2HVG A;  2FUS A;  2VD6 A;  2PTR A;  3C8T A;  1C3C A;  4APB A;  3RRP A;  2O7D A;  4C5S A;  1KQ7 A;  1T6J A;  4FLC A;  5F92 A;  1TJV A; 
#chains in the Genus database with same CATH topology
 4EFC A;  2QVE A;  2J91 A;  1T6P A;  2YV5 A;  3GZH A;  5H8W A;  4YIK A;  2O6Y A;  1Q5N A;  1Q92 A;  2VSF A;  4BAB A;  3KDY A;  1K62 A;  3CI0 K;  3TV2 A;  3OCE A;  5F91 A;  4MWO A;  1GK2 A;  1XMD A;  1HY1 A;  2FEL A;  4ADL A;  2FEN A;  4NLE A;  4FFX A;  1TJW A;  3UNV A;  4C6G A;  1DCN A;  5HW2 A;  1U15 A;  4CQ5 A;  2OHY A;  4NSL A;  5M0I A;  2JAO A;  3E04 A;  3BHG A;  5EYV A;  3CRV A;  4NFL A;  3R6Y A;  4ADM A;  4E88 A;  1Z4M A;  4EEI A;  2NYF A;  1DOF A;  1U16 A;  5D6B A;  1YIS A;  1TJ7 A;  1XL8 A;  3CZO A;  1FUP A;  2X75 A;  3F4S A;  1IW7 D;  1AUW A;  1I0A A;  4MX2 A;  2JAR A;  1Q91 A;  3RD8 A;  2NYN A;  4HGV A;  1JSW A;  2QGA B;  3CRW 1;  4V2R A;  1YFM A;  1FUR A;  2JAW A;  1VDK A;  4V2Q A;  4C5U A;  1J3U A;  1HY0 A;  3F4T A;  2O7B A;  2D27 A;  1Z4K A;  1W27 A;  2YII A;  2VL7 A;  1FUQ A;  4MUM A;  3R6V A;  4C5R A;  4BAA A;  1YFE A;  2RJR A;  1EB4 A;  2D28 C;  2JAU A;  1U0L A;  1TJU A;  5M0J A;  3QBP A;  1XWO A;  1RE5 A;  1C3U A;  4L57 A;  1B8F A;  3R6Q A;  2O7F A;  2PTS A;  4YIH A;  1GKM A;  3OCF A;  4APA A;  1XL7 A;  1MH9 A;  1XLY A;  1GK3 A;  3NZ4 A;  2O78 A;  3NO9 A;  2PFM A;  1Z4L A;  3GTD A;  2E9F A;  2PTQ A;  5EYT A;  1T9H A;  2O7E A;  4A15 A;  2I7D A;  1Z4J A;  1Z4Q A;  4L6C A;  1FUO A;  1K7W A;  4IQJ M;  4WNL A;  2RJS A;  1Y2M A;  3KDZ A;  3F4R A;  3BWV A;  3U13 A;  1GKJ A;  1Z4P X;  2HVG A;  2FUS A;  3U19 A;  1Z4I A;  4L6A A;  1XMC A;  2VD6 A;  2PTR A;  3C8T A;  1C3C A;  4APB A;  2RCN A;  3RRP A;  2O7D A;  4C5S A;  1KQ7 A;  1T6J A;  4FLC A;  5F92 A;  1TJV A; 
#chains in the Genus database with same CATH homology
 4EFC A;  2QVE A;  2J91 A;  1T6P A;  3GZH A;  2O6Y A;  1Q5N A;  4BAB A;  3KDY A;  1K62 A;  3TV2 A;  3OCE A;  5F91 A;  1GK2 A;  1HY1 A;  4ADL A;  4NLE A;  4FFX A;  1TJW A;  3UNV A;  4C6G A;  1DCN A;  5HW2 A;  1U15 A;  4CQ5 A;  2OHY A;  4NSL A;  3E04 A;  3BHG A;  5EYV A;  3R6Y A;  4ADM A;  4EEI A;  2NYF A;  1DOF A;  1U16 A;  5D6B A;  1YIS A;  1TJ7 A;  3CZO A;  1FUP A;  2X75 A;  1AUW A;  1I0A A;  4MX2 A;  3RD8 A;  2NYN A;  4HGV A;  1JSW A;  2QGA B;  4V2R A;  1YFM A;  1FUR A;  1VDK A;  4V2Q A;  4C5U A;  1J3U A;  1HY0 A;  2O7B A;  1W27 A;  2YII A;  1FUQ A;  3R6V A;  4C5R A;  4BAA A;  1YFE A;  2RJR A;  1EB4 A;  1TJU A;  3QBP A;  1XWO A;  1RE5 A;  1C3U A;  1B8F A;  3R6Q A;  2O7F A;  2PTS A;  1GKM A;  3OCF A;  4APA A;  1GK3 A;  3NZ4 A;  2O78 A;  3NO9 A;  2PFM A;  3GTD A;  2E9F A;  2PTQ A;  5EYT A;  2O7E A;  1FUO A;  1K7W A;  2RJS A;  1Y2M A;  3KDZ A;  1GKJ A;  2HVG A;  2FUS A;  2VD6 A;  2PTR A;  3C8T A;  1C3C A;  4APB A;  3RRP A;  2O7D A;  4C5S A;  1KQ7 A;  1T6J A;  4FLC A;  5F92 A;  1TJV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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