1TJ7A

Structure determination and refinement at 2.44 a resolution of argininosuccinate lyase from e. coli
Total Genus 177
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
455
structure length
455
Chain Sequence
LWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Lyase
molecule keywords Argininosuccinate lyase
publication title Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli.
pubmed doi rcsb
total genus 177
structure length 455
sequence length 455
chains with identical sequence B
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2004-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1tj7A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1tj7A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1tj7A02
2X75A 1T6JA 1C3UA 2O7DA 1AUWA 4NSLA 1HY0A 2O7EA 1Q5NA 5D6BA 4FLCA 5F91A 1TJ7A 3BHGA 1FUQA 1YISA 3CZOA 3R6VA 2NYFA 1VDKA 1XWOA 2J91A 4ADMA 1C3CA 1K7WA 1TJWA 3GZHA 4C5SA 3GTDA 4EFCA 4V2RA 2O7FA 1Y2MA 4V2QA 1B8FA 4ADLA 1EB4A 1YFMA 1FUPA 4CQ5A 1KQ7A 4HGVA 1I0AA 3OCEA 2PTRA 3R6QA 2FUSA 2O78A 1U16A 3QBPA 2QVEA 5EYTA 2O6YA 2YIIA 3R6YA 2PFMA 5F92A 2PTQA 1TJVA 2NYNA 2QGAB 5HW2A 1DCNA 3KDYA 3NZ4A 1TJUA 1J3UA 4MX2A 4NLEA 4APAA 2OHYA 4C6GA 4C5UA 2HVGA 3RRPA 1YFEA 4APBA 2VD6A 1FUOA 2PTSA 3NO9A 3UNVA 2E9FA 1FURA 2O7BA 1HY1A 3RD8A 1GKJA 4BABA 3OCFA 1T6PA 1JSWA 1RE5A 1K62A 1GK2A 1W27A 1U15A 1DOFA 2RJSA 3TV2A 2RJRA 4FFXA 3C8TA 3E04A 3KDZA 1GKMA 5EYVA 4C5RA 1GK3A 4BAAA 4EEIA
chains in the Genus database with same CATH superfamily
2D28C 2X75A 1Z4KA 1T6JA 1C3UA 2O7DA 1AUWA 1XL8A 3CRW1 4NSLA 1HY0A 1Z4JA 2O7EA 1Q5NA 5D6BA 1MH9A 4FLCA 5F91A 3BWVA 3F4SA 1TJ7A 3BHGA 1FUQA 1YISA 1Z4PX 3CZOA 3R6VA 2NYFA 1VDKA 1XWOA 3F4RA 4YIHA 2J91A 4YIKA 1C3CA 1K7WA 4ADMA 1TJWA 2JAOA 1IW7D 3GZHA 4C5SA 3GTDA 4EFCA 1Q92A 4V2RA 4IQJM 4E88A 4L6CA 2O7FA 4MWOA 1Y2MA 4V2QA 1B8FA 2VSFA 4ADLA 1EB4A 1YFMA 2D27A 1Z4LA 4WNLA 1Q91A 3F4TA 5H8WA 1FUPA 4A15A 4CQ5A 1KQ7A 2RCNA 2YV5A 1XMCA 4HGVA 1I0AA 4MUMA 3OCEA 2PTRA 3R6QA 3U19A 1XL7A 2FELA 4L6AA 2FUSA 2O78A 1U16A 3QBPA 3CRVA 2QVEA 5EYTA 1Z4IA 2O6YA 2YIIA 3R6YA 2PFMA 5F92A 2PTQA 1TJVA 2NYNA 2QGAB 5HW2A 1DCNA 3KDYA 3NZ4A 1TJUA 1J3UA 4MX2A 4NLEA 4APAA 2OHYA 4C6GA 4C5UA 1Z4QA 2HVGA 3RRPA 1YFEA 4APBA 2VD6A 1FUOA 2PTSA 3CI0K 3U13A 3NO9A 4NFLA 3UNVA 2E9FA 2JAUA 2JAWA 1FURA 1T9HA 2O7BA 1HY1A 3RD8A 1GKJA 4BABA 3OCFA 1T6PA 1JSWA 1RE5A 1K62A 2JARA 1Z4MA 1GK2A 1W27A 1U15A 1DOFA 2RJSA 5M0IA 3TV2A 2RJRA 4FFXA 3C8TA 1XLYA 1U0LA 1XMDA 3E04A 3KDZA 4L57A 5M0JA 1GKMA 5EYVA 2VL7A 2I7DA 4C5RA 1GK3A 4BAAA 4EEIA 2FENA
chains in the Genus database with same CATH topology
2X75A 1T6JA 1C3UA 2O7DA 1AUWA 4NSLA 1HY0A 2O7EA 1Q5NA 5D6BA 4FLCA 5F91A 1TJ7A 3BHGA 1FUQA 1YISA 3CZOA 3R6VA 2NYFA 1VDKA 1XWOA 2J91A 4ADMA 1C3CA 1K7WA 1TJWA 3GZHA 4C5SA 3GTDA 4EFCA 4V2RA 2O7FA 1Y2MA 4V2QA 1B8FA 4ADLA 1EB4A 1YFMA 1FUPA 4CQ5A 1KQ7A 4HGVA 1I0AA 3OCEA 2PTRA 3R6QA 2FUSA 2O78A 1U16A 3QBPA 2QVEA 5EYTA 2O6YA 2YIIA 3R6YA 2PFMA 5F92A 2PTQA 1TJVA 2NYNA 2QGAB 5HW2A 1DCNA 3KDYA 3NZ4A 1TJUA 1J3UA 4MX2A 4NLEA 4APAA 2OHYA 4C6GA 4C5UA 2HVGA 3RRPA 1YFEA 4APBA 2VD6A 1FUOA 2PTSA 3NO9A 3UNVA 2E9FA 1FURA 2O7BA 1HY1A 3RD8A 1GKJA 4BABA 3OCFA 1T6PA 1JSWA 1RE5A 1K62A 1GK2A 1W27A 1U15A 1DOFA 2RJSA 3TV2A 2RJRA 4FFXA 3C8TA 3E04A 3KDZA 1GKMA 5EYVA 4C5RA 1GK3A 4BAAA 4EEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X75 A;  1T6J A;  1C3U A;  2O7D A;  1AUW A;  4NSL A;  1HY0 A;  2O7E A;  1Q5N A;  5D6B A;  4FLC A;  5F91 A;  1TJ7 A;  3BHG A;  1FUQ A;  1YIS A;  3CZO A;  3R6V A;  2NYF A;  1VDK A;  1XWO A;  2J91 A;  4ADM A;  1C3C A;  1K7W A;  1TJW A;  3GZH A;  4C5S A;  3GTD A;  4EFC A;  4V2R A;  2O7F A;  1Y2M A;  4V2Q A;  1B8F A;  4ADL A;  1EB4 A;  1YFM A;  1FUP A;  4CQ5 A;  1KQ7 A;  4HGV A;  1I0A A;  3OCE A;  2PTR A;  3R6Q A;  2FUS A;  2O78 A;  1U16 A;  3QBP A;  2QVE A;  5EYT A;  2O6Y A;  2YII A;  3R6Y A;  2PFM A;  5F92 A;  2PTQ A;  1TJV A;  2NYN A;  2QGA B;  5HW2 A;  1DCN A;  3KDY A;  3NZ4 A;  1TJU A;  1J3U A;  4MX2 A;  4NLE A;  4APA A;  2OHY A;  4C6G A;  4C5U A;  2HVG A;  3RRP A;  1YFE A;  4APB A;  2VD6 A;  1FUO A;  2PTS A;  3NO9 A;  3UNV A;  2E9F A;  1FUR A;  2O7B A;  1HY1 A;  3RD8 A;  1GKJ A;  4BAB A;  3OCF A;  1T6P A;  1JSW A;  1RE5 A;  1K62 A;  1GK2 A;  1W27 A;  1U15 A;  1DOF A;  2RJS A;  3TV2 A;  2RJR A;  4FFX A;  3C8T A;  3E04 A;  3KDZ A;  1GKM A;  5EYV A;  4C5R A;  1GK3 A;  4BAA A;  4EEI A; 
#chains in the Genus database with same CATH topology
 2D28 C;  2X75 A;  1Z4K A;  1T6J A;  1C3U A;  2O7D A;  1AUW A;  1XL8 A;  3CRW 1;  4NSL A;  1HY0 A;  1Z4J A;  2O7E A;  1Q5N A;  5D6B A;  1MH9 A;  4FLC A;  5F91 A;  3BWV A;  3F4S A;  1TJ7 A;  3BHG A;  1FUQ A;  1YIS A;  1Z4P X;  3CZO A;  3R6V A;  2NYF A;  1VDK A;  1XWO A;  3F4R A;  4YIH A;  2J91 A;  4YIK A;  1C3C A;  1K7W A;  4ADM A;  1TJW A;  2JAO A;  1IW7 D;  3GZH A;  4C5S A;  3GTD A;  4EFC A;  1Q92 A;  4V2R A;  4IQJ M;  4E88 A;  4L6C A;  2O7F A;  4MWO A;  1Y2M A;  4V2Q A;  1B8F A;  2VSF A;  4ADL A;  1EB4 A;  1YFM A;  2D27 A;  1Z4L A;  4WNL A;  1Q91 A;  3F4T A;  5H8W A;  1FUP A;  4A15 A;  4CQ5 A;  1KQ7 A;  2RCN A;  2YV5 A;  1XMC A;  4HGV A;  1I0A A;  4MUM A;  3OCE A;  2PTR A;  3R6Q A;  3U19 A;  1XL7 A;  2FEL A;  4L6A A;  2FUS A;  2O78 A;  1U16 A;  3QBP A;  3CRV A;  2QVE A;  5EYT A;  1Z4I A;  2O6Y A;  2YII A;  3R6Y A;  2PFM A;  5F92 A;  2PTQ A;  1TJV A;  2NYN A;  2QGA B;  5HW2 A;  1DCN A;  3KDY A;  3NZ4 A;  1TJU A;  1J3U A;  4MX2 A;  4NLE A;  4APA A;  2OHY A;  4C6G A;  4C5U A;  1Z4Q A;  2HVG A;  3RRP A;  1YFE A;  4APB A;  2VD6 A;  1FUO A;  2PTS A;  3CI0 K;  3U13 A;  3NO9 A;  4NFL A;  3UNV A;  2E9F A;  2JAU A;  2JAW A;  1FUR A;  1T9H A;  2O7B A;  1HY1 A;  3RD8 A;  1GKJ A;  4BAB A;  3OCF A;  1T6P A;  1JSW A;  1RE5 A;  1K62 A;  2JAR A;  1Z4M A;  1GK2 A;  1W27 A;  1U15 A;  1DOF A;  2RJS A;  5M0I A;  3TV2 A;  2RJR A;  4FFX A;  3C8T A;  1XLY A;  1U0L A;  1XMD A;  3E04 A;  3KDZ A;  4L57 A;  5M0J A;  1GKM A;  5EYV A;  2VL7 A;  2I7D A;  4C5R A;  1GK3 A;  4BAA A;  4EEI A;  2FEN A; 
#chains in the Genus database with same CATH homology
 2X75 A;  1T6J A;  1C3U A;  2O7D A;  1AUW A;  4NSL A;  1HY0 A;  2O7E A;  1Q5N A;  5D6B A;  4FLC A;  5F91 A;  1TJ7 A;  3BHG A;  1FUQ A;  1YIS A;  3CZO A;  3R6V A;  2NYF A;  1VDK A;  1XWO A;  2J91 A;  4ADM A;  1C3C A;  1K7W A;  1TJW A;  3GZH A;  4C5S A;  3GTD A;  4EFC A;  4V2R A;  2O7F A;  1Y2M A;  4V2Q A;  1B8F A;  4ADL A;  1EB4 A;  1YFM A;  1FUP A;  4CQ5 A;  1KQ7 A;  4HGV A;  1I0A A;  3OCE A;  2PTR A;  3R6Q A;  2FUS A;  2O78 A;  1U16 A;  3QBP A;  2QVE A;  5EYT A;  2O6Y A;  2YII A;  3R6Y A;  2PFM A;  5F92 A;  2PTQ A;  1TJV A;  2NYN A;  2QGA B;  5HW2 A;  1DCN A;  3KDY A;  3NZ4 A;  1TJU A;  1J3U A;  4MX2 A;  4NLE A;  4APA A;  2OHY A;  4C6G A;  4C5U A;  2HVG A;  3RRP A;  1YFE A;  4APB A;  2VD6 A;  1FUO A;  2PTS A;  3NO9 A;  3UNV A;  2E9F A;  1FUR A;  2O7B A;  1HY1 A;  3RD8 A;  1GKJ A;  4BAB A;  3OCF A;  1T6P A;  1JSW A;  1RE5 A;  1K62 A;  1GK2 A;  1W27 A;  1U15 A;  1DOF A;  2RJS A;  3TV2 A;  2RJR A;  4FFX A;  3C8T A;  3E04 A;  3KDZ A;  1GKM A;  5EYV A;  4C5R A;  1GK3 A;  4BAA A;  4EEI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...