1TJ7A

Structure determination and refinement at 2.44 a resolution of argininosuccinate lyase from e. coli
Total Genus 177
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
455
structure length
455
Chain Sequence
LWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli.
pubmed doi rcsb
molecule tags Lyase
molecule keywords Argininosuccinate lyase
total genus 177
structure length 455
sequence length 455
chains with identical sequence B
ec nomenclature ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date 2004-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF14698 ASL_C2 Argininosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1tj7A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1tj7A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1tj7A02
1U16A 1K62A 4V2RA 2QVEA 3NZ4A 3OCEA 3C8TA 1RE5A 2HVGA 4CQ5A 2PTQA 2X75A 1C3UA 4EFCA 5F92A 5EYTA 1YFMA 3R6VA 1YISA 3RRPA 1DCNA 1T6JA 1TJ7A 3GTDA 2OHYA 2PTSA 1C3CA 1GK3A 2J91A 1TJVA 4C5RA 3GZHA 1JSWA 1TJUA 1FUOA 4NLEA 2O7DA 2E9FA 1FUQA 3RD8A 4HGVA 1HY1A 1VDKA 1GK2A 2QGAB 1AUWA 2O7EA 4ADMA 1KQ7A 5HW2A 1B8FA 3NO9A 3KDYA 3QBPA 1GKMA 4ADLA 1DOFA 3TV2A 3KDZA 4C5SA 5D6BA 4NSLA 1K7WA 2O6YA 4FFXA 3R6QA 1EB4A 1T6PA 3R6YA 4MX2A 2PTRA 2RJSA 2O7BA 4APAA 1Q5NA 1XWOA 5F91A 4C5UA 3CZOA 1FURA 1FUPA 1YFEA 1W27A 2O78A 4BAAA 2NYNA 3BHGA 4APBA 2NYFA 2VD6A 2PFMA 2YIIA 5EYVA 4EEIA 1I0AA 1GKJA 3UNVA 4C6GA 2RJRA 1Y2MA 1HY0A 4FLCA 4BABA 1U15A 1J3UA 3E04A 4V2QA 2FUSA 1TJWA 2O7FA 3OCFA
chains in the Genus database with same CATH superfamily
1U16A 4L6CA 1K62A 3U13A 1Z4IA 4V2RA 2QVEA 3NZ4A 3OCEA 3C8TA 1RE5A 1T9HA 3F4TA 2HVGA 4CQ5A 3F4SA 1Z4JA 2PTQA 2X75A 1C3UA 4EFCA 2JAOA 3CRW1 5F92A 4MWOA 5EYTA 1YFMA 3R6VA 2JAWA 1Z4MA 1IW7D 4L6AA 3BWVA 1U0LA 1YISA 1XL7A 2D28C 3RRPA 1DCNA 1T6JA 2FENA 1TJ7A 3GTDA 2OHYA 2PTSA 1C3CA 1GK3A 2J91A 1TJVA 4IQJM 1MH9A 4C5RA 3U19A 3GZHA 1JSWA 1TJUA 1Z4QA 1FUOA 4NLEA 2O7DA 2E9FA 1FUQA 3RD8A 4E88A 4HGVA 1HY1A 1VDKA 1GK2A 2QGAB 1AUWA 4YIKA 1Z4LA 2O7EA 4ADMA 1KQ7A 5HW2A 1B8FA 4NFLA 3NO9A 3KDYA 2VL7A 3QBPA 1GKMA 4ADLA 1DOFA 3TV2A 3KDZA 4C5SA 5D6BA 4A15A 4NSLA 1K7WA 2O6YA 4FFXA 5M0IA 3R6QA 1EB4A 1T6PA 3R6YA 1Z4KA 4MX2A 2FELA 2PTRA 2RJSA 2O7BA 4APAA 1XMCA 1Q5NA 4L57A 1XWOA 5F91A 4C5UA 3CZOA 1FURA 1FUPA 1YFEA 4YIHA 1W27A 2RCNA 2O78A 5H8WA 4BAAA 2NYNA 3BHGA 1Q91A 4APBA 1XMDA 4WNLA 2D27A 2NYFA 2VD6A 2PFMA 1XL8A 1Z4PX 2YIIA 2VSFA 1Q92A 5EYVA 4EEIA 1I0AA 1GKJA 3UNVA 2JARA 2I7DA 3F4RA 1XLYA 4MUMA 4C6GA 5M0JA 2RJRA 1Y2MA 1HY0A 4FLCA 4BABA 1U15A 1J3UA 3E04A 4V2QA 2JAUA 3CRVA 2FUSA 3CI0K 2YV5A 1TJWA 2O7FA 3OCFA
chains in the Genus database with same CATH topology
1U16A 1K62A 4V2RA 2QVEA 3NZ4A 3OCEA 3C8TA 1RE5A 2HVGA 4CQ5A 2PTQA 2X75A 1C3UA 4EFCA 5F92A 5EYTA 1YFMA 3R6VA 1YISA 3RRPA 1DCNA 1T6JA 1TJ7A 3GTDA 2OHYA 2PTSA 1C3CA 1GK3A 2J91A 1TJVA 4C5RA 3GZHA 1JSWA 1TJUA 1FUOA 4NLEA 2O7DA 2E9FA 1FUQA 3RD8A 4HGVA 1HY1A 1VDKA 1GK2A 2QGAB 1AUWA 2O7EA 4ADMA 1KQ7A 5HW2A 1B8FA 3NO9A 3KDYA 3QBPA 1GKMA 4ADLA 1DOFA 3TV2A 3KDZA 4C5SA 5D6BA 4NSLA 1K7WA 2O6YA 4FFXA 3R6QA 1EB4A 1T6PA 3R6YA 4MX2A 2PTRA 2RJSA 2O7BA 4APAA 1Q5NA 1XWOA 5F91A 4C5UA 3CZOA 1FURA 1FUPA 1YFEA 1W27A 2O78A 4BAAA 2NYNA 3BHGA 4APBA 2NYFA 2VD6A 2PFMA 2YIIA 5EYVA 4EEIA 1I0AA 1GKJA 3UNVA 4C6GA 2RJRA 1Y2MA 1HY0A 4FLCA 4BABA 1U15A 1J3UA 3E04A 4V2QA 2FUSA 1TJWA 2O7FA 3OCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U16 A;  1K62 A;  4V2R A;  2QVE A;  3NZ4 A;  3OCE A;  3C8T A;  1RE5 A;  2HVG A;  4CQ5 A;  2PTQ A;  2X75 A;  1C3U A;  4EFC A;  5F92 A;  5EYT A;  1YFM A;  3R6V A;  1YIS A;  3RRP A;  1DCN A;  1T6J A;  1TJ7 A;  3GTD A;  2OHY A;  2PTS A;  1C3C A;  1GK3 A;  2J91 A;  1TJV A;  4C5R A;  3GZH A;  1JSW A;  1TJU A;  1FUO A;  4NLE A;  2O7D A;  2E9F A;  1FUQ A;  3RD8 A;  4HGV A;  1HY1 A;  1VDK A;  1GK2 A;  2QGA B;  1AUW A;  2O7E A;  4ADM A;  1KQ7 A;  5HW2 A;  1B8F A;  3NO9 A;  3KDY A;  3QBP A;  1GKM A;  4ADL A;  1DOF A;  3TV2 A;  3KDZ A;  4C5S A;  5D6B A;  4NSL A;  1K7W A;  2O6Y A;  4FFX A;  3R6Q A;  1EB4 A;  1T6P A;  3R6Y A;  4MX2 A;  2PTR A;  2RJS A;  2O7B A;  4APA A;  1Q5N A;  1XWO A;  5F91 A;  4C5U A;  3CZO A;  1FUR A;  1FUP A;  1YFE A;  1W27 A;  2O78 A;  4BAA A;  2NYN A;  3BHG A;  4APB A;  2NYF A;  2VD6 A;  2PFM A;  2YII A;  5EYV A;  4EEI A;  1I0A A;  1GKJ A;  3UNV A;  4C6G A;  2RJR A;  1Y2M A;  1HY0 A;  4FLC A;  4BAB A;  1U15 A;  1J3U A;  3E04 A;  4V2Q A;  2FUS A;  1TJW A;  2O7F A;  3OCF A; 
#chains in the Genus database with same CATH topology
 1U16 A;  4L6C A;  1K62 A;  3U13 A;  1Z4I A;  4V2R A;  2QVE A;  3NZ4 A;  3OCE A;  3C8T A;  1RE5 A;  1T9H A;  3F4T A;  2HVG A;  4CQ5 A;  3F4S A;  1Z4J A;  2PTQ A;  2X75 A;  1C3U A;  4EFC A;  2JAO A;  3CRW 1;  5F92 A;  4MWO A;  5EYT A;  1YFM A;  3R6V A;  2JAW A;  1Z4M A;  1IW7 D;  4L6A A;  3BWV A;  1U0L A;  1YIS A;  1XL7 A;  2D28 C;  3RRP A;  1DCN A;  1T6J A;  2FEN A;  1TJ7 A;  3GTD A;  2OHY A;  2PTS A;  1C3C A;  1GK3 A;  2J91 A;  1TJV A;  4IQJ M;  1MH9 A;  4C5R A;  3U19 A;  3GZH A;  1JSW A;  1TJU A;  1Z4Q A;  1FUO A;  4NLE A;  2O7D A;  2E9F A;  1FUQ A;  3RD8 A;  4E88 A;  4HGV A;  1HY1 A;  1VDK A;  1GK2 A;  2QGA B;  1AUW A;  4YIK A;  1Z4L A;  2O7E A;  4ADM A;  1KQ7 A;  5HW2 A;  1B8F A;  4NFL A;  3NO9 A;  3KDY A;  2VL7 A;  3QBP A;  1GKM A;  4ADL A;  1DOF A;  3TV2 A;  3KDZ A;  4C5S A;  5D6B A;  4A15 A;  4NSL A;  1K7W A;  2O6Y A;  4FFX A;  5M0I A;  3R6Q A;  1EB4 A;  1T6P A;  3R6Y A;  1Z4K A;  4MX2 A;  2FEL A;  2PTR A;  2RJS A;  2O7B A;  4APA A;  1XMC A;  1Q5N A;  4L57 A;  1XWO A;  5F91 A;  4C5U A;  3CZO A;  1FUR A;  1FUP A;  1YFE A;  4YIH A;  1W27 A;  2RCN A;  2O78 A;  5H8W A;  4BAA A;  2NYN A;  3BHG A;  1Q91 A;  4APB A;  1XMD A;  4WNL A;  2D27 A;  2NYF A;  2VD6 A;  2PFM A;  1XL8 A;  1Z4P X;  2YII A;  2VSF A;  1Q92 A;  5EYV A;  4EEI A;  1I0A A;  1GKJ A;  3UNV A;  2JAR A;  2I7D A;  3F4R A;  1XLY A;  4MUM A;  4C6G A;  5M0J A;  2RJR A;  1Y2M A;  1HY0 A;  4FLC A;  4BAB A;  1U15 A;  1J3U A;  3E04 A;  4V2Q A;  2JAU A;  3CRV A;  2FUS A;  3CI0 K;  2YV5 A;  1TJW A;  2O7F A;  3OCF A; 
#chains in the Genus database with same CATH homology
 1U16 A;  1K62 A;  4V2R A;  2QVE A;  3NZ4 A;  3OCE A;  3C8T A;  1RE5 A;  2HVG A;  4CQ5 A;  2PTQ A;  2X75 A;  1C3U A;  4EFC A;  5F92 A;  5EYT A;  1YFM A;  3R6V A;  1YIS A;  3RRP A;  1DCN A;  1T6J A;  1TJ7 A;  3GTD A;  2OHY A;  2PTS A;  1C3C A;  1GK3 A;  2J91 A;  1TJV A;  4C5R A;  3GZH A;  1JSW A;  1TJU A;  1FUO A;  4NLE A;  2O7D A;  2E9F A;  1FUQ A;  3RD8 A;  4HGV A;  1HY1 A;  1VDK A;  1GK2 A;  2QGA B;  1AUW A;  2O7E A;  4ADM A;  1KQ7 A;  5HW2 A;  1B8F A;  3NO9 A;  3KDY A;  3QBP A;  1GKM A;  4ADL A;  1DOF A;  3TV2 A;  3KDZ A;  4C5S A;  5D6B A;  4NSL A;  1K7W A;  2O6Y A;  4FFX A;  3R6Q A;  1EB4 A;  1T6P A;  3R6Y A;  4MX2 A;  2PTR A;  2RJS A;  2O7B A;  4APA A;  1Q5N A;  1XWO A;  5F91 A;  4C5U A;  3CZO A;  1FUR A;  1FUP A;  1YFE A;  1W27 A;  2O78 A;  4BAA A;  2NYN A;  3BHG A;  4APB A;  2NYF A;  2VD6 A;  2PFM A;  2YII A;  5EYV A;  4EEI A;  1I0A A;  1GKJ A;  3UNV A;  4C6G A;  2RJR A;  1Y2M A;  1HY0 A;  4FLC A;  4BAB A;  1U15 A;  1J3U A;  3E04 A;  4V2Q A;  2FUS A;  1TJW A;  2O7F A;  3OCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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