2O6YA

Tyrosine ammonia-lyase from rhodobacter sphaeroides
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o6yA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o6yA02
1AUWA 1C3CA 3R6VA 1DOFA 3GZHA 3QBPA 3NO9A 5EYVA 1GK2A 1J3UA 2RJSA 1FUPA 3UNVA 2QVEA 1FUOA 4CQ5A 4ADLA 4NSLA 1Y2MA 2O7FA 4C5UA 1W27A 3E04A 4FFXA 1B8FA 1GKMA 2FUSA 1GKJA 4HGVA 4FLCA 1HY1A 4MX2A 3GTDA 2VD6A 1RE5A 3BHGA 4APAA 1HY0A 4C5SA 3NZ4A 5F92A 2PTRA 3CZOA 1DCNA 2NYFA 1U15A 1K7WA 1KQ7A 1K62A 1TJ7A 2E9FA 4C6GA 2O7BA 1TJWA 2HVGA 3OCFA 4BAAA 1FURA 2X75A 5EYTA 4C5RA 5HW2A 4BABA 2O7DA 1TJUA 2OHYA 1C3UA 3KDZA 1YISA 2O6YA 2PTQA 1VDKA 2YIIA 2O7EA 4NLEA 3OCEA 4V2QA 4V2RA 5F91A 1JSWA 2PTSA 1T6JA 2J91A 2NYNA 2RJRA 1XWOA 1YFEA 1U16A 3RD8A 4ADMA 1GK3A 2PFMA 2O78A 1I0AA 3R6YA 3KDYA 3RRPA 4APBA 1Q5NA 4EFCA 1YFMA 5D6BA 1FUQA 3R6QA 3C8TA 1TJVA 4EEIA 3TV2A 2QGAB 1EB4A 1T6PA
chains in the Genus database with same CATH superfamily
1AUWA 1C3CA 3R6VA 3CRVA 4A15A 1DOFA 3GZHA 3QBPA 3NO9A 5EYVA 1GK2A 1J3UA 2RJSA 1FUPA 3UNVA 2QVEA 4WNLA 1FUOA 4CQ5A 4ADLA 4NSLA 1Y2MA 1XMCA 2O7FA 4C5UA 1W27A 3E04A 4FFXA 1B8FA 1GKMA 2FUSA 1GKJA 4HGVA 4FLCA 1HY1A 4MX2A 3GTDA 2VD6A 1RE5A 1XMDA 3BHGA 4APAA 2FENA 5M0IA 1HY0A 4C5SA 1XL8A 3NZ4A 5F92A 2PTRA 3CZOA 1DCNA 2NYFA 1U15A 5M0JA 1K7WA 1KQ7A 1K62A 1TJ7A 2E9FA 2VL7A 4C6GA 2O7BA 1TJWA 2HVGA 3OCFA 4BAAA 1FURA 2X75A 5EYTA 4C5RA 5HW2A 4BABA 2O7DA 1TJUA 2OHYA 1C3UA 3KDZA 1YISA 5H8WA 1XLYA 2FELA 2O6YA 2PTQA 1VDKA 2YIIA 2O7EA 4NLEA 3OCEA 4V2QA 4V2RA 5F91A 1JSWA 2PTSA 1T6JA 2J91A 2NYNA 2RJRA 1XWOA 1YFEA 1U16A 2VSFA 3RD8A 4ADMA 1XL7A 1GK3A 2PFMA 2O78A 1I0AA 3R6YA 3KDYA 3RRPA 4APBA 1Q5NA 4EFCA 3CRW1 1YFMA 5D6BA 1FUQA 3R6QA 3C8TA 1TJVA 4EEIA 3TV2A 2QGAB 1EB4A 1T6PA
chains in the Genus database with same CATH topology
1AUWA 1C3CA 3R6VA 1DOFA 3GZHA 3QBPA 3NO9A 5EYVA 1GK2A 1J3UA 2RJSA 1FUPA 3UNVA 2QVEA 1FUOA 4CQ5A 4ADLA 4NSLA 1Y2MA 2O7FA 4C5UA 1W27A 3E04A 4FFXA 1B8FA 1GKMA 2FUSA 1GKJA 4HGVA 4FLCA 1HY1A 4MX2A 3GTDA 2VD6A 1RE5A 3BHGA 4APAA 1HY0A 4C5SA 3NZ4A 5F92A 2PTRA 3CZOA 1DCNA 2NYFA 1U15A 1K7WA 1KQ7A 1K62A 1TJ7A 2E9FA 4C6GA 2O7BA 1TJWA 2HVGA 3OCFA 4BAAA 1FURA 2X75A 5EYTA 4C5RA 5HW2A 4BABA 2O7DA 1TJUA 2OHYA 1C3UA 3KDZA 1YISA 2O6YA 2PTQA 1VDKA 2YIIA 2O7EA 4NLEA 3OCEA 4V2QA 4V2RA 5F91A 1JSWA 2PTSA 1T6JA 2J91A 2NYNA 2RJRA 1XWOA 1YFEA 1U16A 3RD8A 4ADMA 1GK3A 2PFMA 2O78A 1I0AA 3R6YA 3KDYA 3RRPA 4APBA 1Q5NA 4EFCA 1YFMA 5D6BA 1FUQA 3R6QA 3C8TA 1TJVA 4EEIA 3TV2A 2QGAB 1EB4A 1T6PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AUW A;  1C3C A;  3R6V A;  1DOF A;  3GZH A;  3QBP A;  3NO9 A;  5EYV A;  1GK2 A;  1J3U A;  2RJS A;  1FUP A;  3UNV A;  2QVE A;  1FUO A;  4CQ5 A;  4ADL A;  4NSL A;  1Y2M A;  2O7F A;  4C5U A;  1W27 A;  3E04 A;  4FFX A;  1B8F A;  1GKM A;  2FUS A;  1GKJ A;  4HGV A;  4FLC A;  1HY1 A;  4MX2 A;  3GTD A;  2VD6 A;  1RE5 A;  3BHG A;  4APA A;  1HY0 A;  4C5S A;  3NZ4 A;  5F92 A;  2PTR A;  3CZO A;  1DCN A;  2NYF A;  1U15 A;  1K7W A;  1KQ7 A;  1K62 A;  1TJ7 A;  2E9F A;  4C6G A;  2O7B A;  1TJW A;  2HVG A;  3OCF A;  4BAA A;  1FUR A;  2X75 A;  5EYT A;  4C5R A;  5HW2 A;  4BAB A;  2O7D A;  1TJU A;  2OHY A;  1C3U A;  3KDZ A;  1YIS A;  2O6Y A;  2PTQ A;  1VDK A;  2YII A;  2O7E A;  4NLE A;  3OCE A;  4V2Q A;  4V2R A;  5F91 A;  1JSW A;  2PTS A;  1T6J A;  2J91 A;  2NYN A;  2RJR A;  1XWO A;  1YFE A;  1U16 A;  3RD8 A;  4ADM A;  1GK3 A;  2PFM A;  2O78 A;  1I0A A;  3R6Y A;  3KDY A;  3RRP A;  4APB A;  1Q5N A;  4EFC A;  1YFM A;  5D6B A;  1FUQ A;  3R6Q A;  3C8T A;  1TJV A;  4EEI A;  3TV2 A;  2QGA B;  1EB4 A;  1T6P A; 
#chains in the Genus database with same CATH topology
 1AUW A;  1C3C A;  3R6V A;  3CRV A;  4A15 A;  1DOF A;  3GZH A;  3QBP A;  3NO9 A;  5EYV A;  1GK2 A;  1J3U A;  2RJS A;  1FUP A;  3UNV A;  2QVE A;  4WNL A;  1FUO A;  4CQ5 A;  4ADL A;  4NSL A;  1Y2M A;  1XMC A;  2O7F A;  4C5U A;  1W27 A;  3E04 A;  4FFX A;  1B8F A;  1GKM A;  2FUS A;  1GKJ A;  4HGV A;  4FLC A;  1HY1 A;  4MX2 A;  3GTD A;  2VD6 A;  1RE5 A;  1XMD A;  3BHG A;  4APA A;  2FEN A;  5M0I A;  1HY0 A;  4C5S A;  1XL8 A;  3NZ4 A;  5F92 A;  2PTR A;  3CZO A;  1DCN A;  2NYF A;  1U15 A;  5M0J A;  1K7W A;  1KQ7 A;  1K62 A;  1TJ7 A;  2E9F A;  2VL7 A;  4C6G A;  2O7B A;  1TJW A;  2HVG A;  3OCF A;  4BAA A;  1FUR A;  2X75 A;  5EYT A;  4C5R A;  5HW2 A;  4BAB A;  2O7D A;  1TJU A;  2OHY A;  1C3U A;  3KDZ A;  1YIS A;  5H8W A;  1XLY A;  2FEL A;  2O6Y A;  2PTQ A;  1VDK A;  2YII A;  2O7E A;  4NLE A;  3OCE A;  4V2Q A;  4V2R A;  5F91 A;  1JSW A;  2PTS A;  1T6J A;  2J91 A;  2NYN A;  2RJR A;  1XWO A;  1YFE A;  1U16 A;  2VSF A;  3RD8 A;  4ADM A;  1XL7 A;  1GK3 A;  2PFM A;  2O78 A;  1I0A A;  3R6Y A;  3KDY A;  3RRP A;  4APB A;  1Q5N A;  4EFC A;  3CRW 1;  1YFM A;  5D6B A;  1FUQ A;  3R6Q A;  3C8T A;  1TJV A;  4EEI A;  3TV2 A;  2QGA B;  1EB4 A;  1T6P A; 
#chains in the Genus database with same CATH homology
 1AUW A;  1C3C A;  3R6V A;  1DOF A;  3GZH A;  3QBP A;  3NO9 A;  5EYV A;  1GK2 A;  1J3U A;  2RJS A;  1FUP A;  3UNV A;  2QVE A;  1FUO A;  4CQ5 A;  4ADL A;  4NSL A;  1Y2M A;  2O7F A;  4C5U A;  1W27 A;  3E04 A;  4FFX A;  1B8F A;  1GKM A;  2FUS A;  1GKJ A;  4HGV A;  4FLC A;  1HY1 A;  4MX2 A;  3GTD A;  2VD6 A;  1RE5 A;  3BHG A;  4APA A;  1HY0 A;  4C5S A;  3NZ4 A;  5F92 A;  2PTR A;  3CZO A;  1DCN A;  2NYF A;  1U15 A;  1K7W A;  1KQ7 A;  1K62 A;  1TJ7 A;  2E9F A;  4C6G A;  2O7B A;  1TJW A;  2HVG A;  3OCF A;  4BAA A;  1FUR A;  2X75 A;  5EYT A;  4C5R A;  5HW2 A;  4BAB A;  2O7D A;  1TJU A;  2OHY A;  1C3U A;  3KDZ A;  1YIS A;  2O6Y A;  2PTQ A;  1VDK A;  2YII A;  2O7E A;  4NLE A;  3OCE A;  4V2Q A;  4V2R A;  5F91 A;  1JSW A;  2PTS A;  1T6J A;  2J91 A;  2NYN A;  2RJR A;  1XWO A;  1YFE A;  1U16 A;  3RD8 A;  4ADM A;  1GK3 A;  2PFM A;  2O78 A;  1I0A A;  3R6Y A;  3KDY A;  3RRP A;  4APB A;  1Q5N A;  4EFC A;  1YFM A;  5D6B A;  1FUQ A;  3R6Q A;  3C8T A;  1TJV A;  4EEI A;  3TV2 A;  2QGA B;  1EB4 A;  1T6P A; 
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