2O6YA

Tyrosine ammonia-lyase from rhodobacter sphaeroides
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o6yA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o6yA02
2VD6A 4BABA 1I0AA 1C3UA 4FFXA 5EYTA 1GK3A 1GKMA 1DOFA 1TJWA 2O7EA 2PTQA 1Y2MA 3NZ4A 2PTRA 2RJRA 3NO9A 2QVEA 1RE5A 4BAAA 1Q5NA 4EFCA 3R6YA 1YFMA 3RD8A 3RRPA 2O6YA 1K62A 2OHYA 1TJUA 1YFEA 2HVGA 5HW2A 4CQ5A 1TJVA 1B8FA 1VDKA 4ADMA 1T6PA 1GKJA 1W27A 3TV2A 1AUWA 3OCEA 2X75A 1T6JA 3GZHA 1FUOA 1C3CA 1TJ7A 1U16A 4C5UA 5F91A 1FURA 1HY0A 4C5RA 4MX2A 4V2QA 3KDYA 3BHGA 3R6VA 2O78A 4APAA 1K7WA 2NYFA 3KDZA 5F92A 1XWOA 2O7BA 1U15A 5D6BA 2FUSA 3C8TA 2QGAB 3UNVA 4ADLA 1EB4A 1FUPA 3R6QA 2NYNA 4FLCA 4NSLA 2J91A 4NLEA 1HY1A 2O7FA 3CZOA 1GK2A 5EYVA 2E9FA 1YISA 2O7DA 3QBPA 2RJSA 3E04A 3OCFA 4C5SA 4C6GA 1DCNA 4EEIA 4V2RA 1JSWA 3GTDA 4APBA 2PTSA 1KQ7A 2YIIA 1FUQA 1J3UA 4HGVA 2PFMA
chains in the Genus database with same CATH superfamily
2VD6A 4BABA 1I0AA 1C3UA 4FFXA 4A15A 5EYTA 1XMCA 1GK3A 1GKMA 1DOFA 1TJWA 2O7EA 2PTQA 1Y2MA 3NZ4A 2PTRA 2RJRA 3NO9A 2QVEA 1RE5A 4BAAA 1Q5NA 4EFCA 1XL8A 3R6YA 1YFMA 3RD8A 3RRPA 2O6YA 1K62A 2OHYA 1TJUA 1YFEA 2HVGA 5HW2A 4CQ5A 2FELA 1TJVA 1B8FA 1VDKA 4ADMA 1T6PA 1GKJA 1W27A 3TV2A 4WNLA 1AUWA 3OCEA 2X75A 5H8WA 1T6JA 3GZHA 1FUOA 1C3CA 1XMDA 1XLYA 1TJ7A 1U16A 4C5UA 5F91A 1FURA 1HY0A 3CRVA 4C5RA 4MX2A 4V2QA 3KDYA 3BHGA 3R6VA 2O78A 3CRW1 4APAA 1K7WA 2NYFA 3KDZA 2VL7A 5F92A 1XWOA 2O7BA 1U15A 5D6BA 2FUSA 3C8TA 2QGAB 3UNVA 4ADLA 2VSFA 1EB4A 1FUPA 3R6QA 2NYNA 5M0JA 4FLCA 4NSLA 2FENA 2J91A 4NLEA 1HY1A 2O7FA 3CZOA 1GK2A 2E9FA 5EYVA 1YISA 2O7DA 1XL7A 3QBPA 2RJSA 3E04A 3OCFA 4C5SA 4C6GA 1DCNA 4EEIA 4V2RA 1JSWA 3GTDA 4APBA 2PTSA 1KQ7A 2YIIA 5M0IA 1FUQA 1J3UA 4HGVA 2PFMA
chains in the Genus database with same CATH topology
2VD6A 4BABA 1I0AA 1C3UA 4FFXA 5EYTA 1GK3A 1GKMA 1DOFA 1TJWA 2O7EA 2PTQA 1Y2MA 3NZ4A 2PTRA 2RJRA 3NO9A 2QVEA 1RE5A 4BAAA 1Q5NA 4EFCA 3R6YA 1YFMA 3RD8A 3RRPA 2O6YA 1K62A 2OHYA 1TJUA 1YFEA 2HVGA 5HW2A 4CQ5A 1TJVA 1B8FA 1VDKA 4ADMA 1T6PA 1GKJA 1W27A 3TV2A 1AUWA 3OCEA 2X75A 1T6JA 3GZHA 1FUOA 1C3CA 1TJ7A 1U16A 4C5UA 5F91A 1FURA 1HY0A 4C5RA 4MX2A 4V2QA 3KDYA 3BHGA 3R6VA 2O78A 4APAA 1K7WA 2NYFA 3KDZA 5F92A 1XWOA 2O7BA 1U15A 5D6BA 2FUSA 3C8TA 2QGAB 3UNVA 4ADLA 1EB4A 1FUPA 3R6QA 2NYNA 4FLCA 4NSLA 2J91A 4NLEA 1HY1A 2O7FA 3CZOA 1GK2A 5EYVA 2E9FA 1YISA 2O7DA 3QBPA 2RJSA 3E04A 3OCFA 4C5SA 4C6GA 1DCNA 4EEIA 4V2RA 1JSWA 3GTDA 4APBA 2PTSA 1KQ7A 2YIIA 1FUQA 1J3UA 4HGVA 2PFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VD6 A;  4BAB A;  1I0A A;  1C3U A;  4FFX A;  5EYT A;  1GK3 A;  1GKM A;  1DOF A;  1TJW A;  2O7E A;  2PTQ A;  1Y2M A;  3NZ4 A;  2PTR A;  2RJR A;  3NO9 A;  2QVE A;  1RE5 A;  4BAA A;  1Q5N A;  4EFC A;  3R6Y A;  1YFM A;  3RD8 A;  3RRP A;  2O6Y A;  1K62 A;  2OHY A;  1TJU A;  1YFE A;  2HVG A;  5HW2 A;  4CQ5 A;  1TJV A;  1B8F A;  1VDK A;  4ADM A;  1T6P A;  1GKJ A;  1W27 A;  3TV2 A;  1AUW A;  3OCE A;  2X75 A;  1T6J A;  3GZH A;  1FUO A;  1C3C A;  1TJ7 A;  1U16 A;  4C5U A;  5F91 A;  1FUR A;  1HY0 A;  4C5R A;  4MX2 A;  4V2Q A;  3KDY A;  3BHG A;  3R6V A;  2O78 A;  4APA A;  1K7W A;  2NYF A;  3KDZ A;  5F92 A;  1XWO A;  2O7B A;  1U15 A;  5D6B A;  2FUS A;  3C8T A;  2QGA B;  3UNV A;  4ADL A;  1EB4 A;  1FUP A;  3R6Q A;  2NYN A;  4FLC A;  4NSL A;  2J91 A;  4NLE A;  1HY1 A;  2O7F A;  3CZO A;  1GK2 A;  5EYV A;  2E9F A;  1YIS A;  2O7D A;  3QBP A;  2RJS A;  3E04 A;  3OCF A;  4C5S A;  4C6G A;  1DCN A;  4EEI A;  4V2R A;  1JSW A;  3GTD A;  4APB A;  2PTS A;  1KQ7 A;  2YII A;  1FUQ A;  1J3U A;  4HGV A;  2PFM A; 
#chains in the Genus database with same CATH topology
 2VD6 A;  4BAB A;  1I0A A;  1C3U A;  4FFX A;  4A15 A;  5EYT A;  1XMC A;  1GK3 A;  1GKM A;  1DOF A;  1TJW A;  2O7E A;  2PTQ A;  1Y2M A;  3NZ4 A;  2PTR A;  2RJR A;  3NO9 A;  2QVE A;  1RE5 A;  4BAA A;  1Q5N A;  4EFC A;  1XL8 A;  3R6Y A;  1YFM A;  3RD8 A;  3RRP A;  2O6Y A;  1K62 A;  2OHY A;  1TJU A;  1YFE A;  2HVG A;  5HW2 A;  4CQ5 A;  2FEL A;  1TJV A;  1B8F A;  1VDK A;  4ADM A;  1T6P A;  1GKJ A;  1W27 A;  3TV2 A;  4WNL A;  1AUW A;  3OCE A;  2X75 A;  5H8W A;  1T6J A;  3GZH A;  1FUO A;  1C3C A;  1XMD A;  1XLY A;  1TJ7 A;  1U16 A;  4C5U A;  5F91 A;  1FUR A;  1HY0 A;  3CRV A;  4C5R A;  4MX2 A;  4V2Q A;  3KDY A;  3BHG A;  3R6V A;  2O78 A;  3CRW 1;  4APA A;  1K7W A;  2NYF A;  3KDZ A;  2VL7 A;  5F92 A;  1XWO A;  2O7B A;  1U15 A;  5D6B A;  2FUS A;  3C8T A;  2QGA B;  3UNV A;  4ADL A;  2VSF A;  1EB4 A;  1FUP A;  3R6Q A;  2NYN A;  5M0J A;  4FLC A;  4NSL A;  2FEN A;  2J91 A;  4NLE A;  1HY1 A;  2O7F A;  3CZO A;  1GK2 A;  2E9F A;  5EYV A;  1YIS A;  2O7D A;  1XL7 A;  3QBP A;  2RJS A;  3E04 A;  3OCF A;  4C5S A;  4C6G A;  1DCN A;  4EEI A;  4V2R A;  1JSW A;  3GTD A;  4APB A;  2PTS A;  1KQ7 A;  2YII A;  5M0I A;  1FUQ A;  1J3U A;  4HGV A;  2PFM A; 
#chains in the Genus database with same CATH homology
 2VD6 A;  4BAB A;  1I0A A;  1C3U A;  4FFX A;  5EYT A;  1GK3 A;  1GKM A;  1DOF A;  1TJW A;  2O7E A;  2PTQ A;  1Y2M A;  3NZ4 A;  2PTR A;  2RJR A;  3NO9 A;  2QVE A;  1RE5 A;  4BAA A;  1Q5N A;  4EFC A;  3R6Y A;  1YFM A;  3RD8 A;  3RRP A;  2O6Y A;  1K62 A;  2OHY A;  1TJU A;  1YFE A;  2HVG A;  5HW2 A;  4CQ5 A;  1TJV A;  1B8F A;  1VDK A;  4ADM A;  1T6P A;  1GKJ A;  1W27 A;  3TV2 A;  1AUW A;  3OCE A;  2X75 A;  1T6J A;  3GZH A;  1FUO A;  1C3C A;  1TJ7 A;  1U16 A;  4C5U A;  5F91 A;  1FUR A;  1HY0 A;  4C5R A;  4MX2 A;  4V2Q A;  3KDY A;  3BHG A;  3R6V A;  2O78 A;  4APA A;  1K7W A;  2NYF A;  3KDZ A;  5F92 A;  1XWO A;  2O7B A;  1U15 A;  5D6B A;  2FUS A;  3C8T A;  2QGA B;  3UNV A;  4ADL A;  1EB4 A;  1FUP A;  3R6Q A;  2NYN A;  4FLC A;  4NSL A;  2J91 A;  4NLE A;  1HY1 A;  2O7F A;  3CZO A;  1GK2 A;  5EYV A;  2E9F A;  1YIS A;  2O7D A;  3QBP A;  2RJS A;  3E04 A;  3OCF A;  4C5S A;  4C6G A;  1DCN A;  4EEI A;  4V2R A;  1JSW A;  3GTD A;  4APB A;  2PTS A;  1KQ7 A;  2YII A;  1FUQ A;  1J3U A;  4HGV A;  2PFM A; 
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