2O6YA

Tyrosine ammonia-lyase from rhodobacter sphaeroides
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
b'PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Putative histidine ammonia-lyase
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o6yA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o6yA02
4FLCA 4C5UA 2FUSA 1YFEA 1JSWA 5D6BA 1KQ7A 2O7DA 1FUQA 3OCFA 1RE5A 2PFMA 3UNVA 4CQ5A 1J3UA 2QGAB 4BAAA 3RD8A 4ADLA 1TJUA 2HVGA 3R6VA 1U16A 1EB4A 5EYTA 1B8FA 3C8TA 3BHGA 2O6YA 2VD6A 2O7BA 1K62A 1GKJA 1AUWA 2O78A 2NYFA 1T6JA 1GK3A 1GKMA 4MX2A 4HGVA 4EEIA 1TJ7A 5HW2A 4V2QA 4C6GA 3TV2A 1C3UA 1FURA 3E04A 1TJVA 3KDYA 4APAA 4C5RA 2X75A 1TJWA 5EYVA 2PTQA 2OHYA 1HY1A 3NO9A 3CZOA 4APBA 1HY0A 3OCEA 1VDKA 3NZ4A 1T6PA 3GZHA 1GK2A 1W27A 2J91A 2E9FA 4NLEA 2NYNA 1U15A 3RRPA 3QBPA 1I0AA 1YFMA 3R6YA 1FUOA 1Y2MA 5F92A 1XWOA 4EFCA 2RJSA 1K7WA 3KDZA 2O7EA 5F91A 4V2RA 2YIIA 1DOFA 2PTSA 3GTDA 1Q5NA 1DCNA 4FFXA 4C5SA 1C3CA 1FUPA 4BABA 4ADMA 2PTRA 2QVEA 2O7FA 1YISA 3R6QA 4NSLA 2RJRA
chains in the Genus database with same CATH superfamily
4FLCA 4C5UA 2FUSA 1YFEA 1JSWA 5D6BA 1KQ7A 2O7DA 1FUQA 3OCFA 5H8WA 1RE5A 2PFMA 3UNVA 4CQ5A 1J3UA 2QGAB 4BAAA 3RD8A 4ADLA 1TJUA 2HVGA 3R6VA 1U16A 1EB4A 5EYTA 1XMDA 1B8FA 3C8TA 3BHGA 2O6YA 5M0IA 2VD6A 2O7BA 1K62A 1GKJA 1AUWA 2O78A 2NYFA 1T6JA 1GK3A 1GKMA 4MX2A 3CRVA 4HGVA 4EEIA 1TJ7A 5HW2A 4V2QA 4C6GA 3TV2A 1C3UA 1FURA 3E04A 1TJVA 3KDYA 4APAA 4C5RA 2X75A 1TJWA 5EYVA 2PTQA 2OHYA 1HY1A 3NO9A 3CZOA 4APBA 1HY0A 3OCEA 1VDKA 3NZ4A 1T6PA 3GZHA 2FELA 1XL8A 1GK2A 1W27A 2J91A 4WNLA 2E9FA 4NLEA 2NYNA 3CRW1 1U15A 3RRPA 2VL7A 3QBPA 1I0AA 1YFMA 3R6YA 1FUOA 1Y2MA 5F92A 1XWOA 4EFCA 2RJSA 2FENA 1K7WA 3KDZA 2O7EA 5F91A 4A15A 4V2RA 2YIIA 1XLYA 1XMCA 2VSFA 5M0JA 1DOFA 2PTSA 3GTDA 1Q5NA 1DCNA 4FFXA 1XL7A 4C5SA 1C3CA 1FUPA 4BABA 4ADMA 2PTRA 2QVEA 2O7FA 1YISA 3R6QA 4NSLA 2RJRA
chains in the Genus database with same CATH topology
4FLCA 4C5UA 2FUSA 1YFEA 1JSWA 5D6BA 1KQ7A 2O7DA 1FUQA 3OCFA 1RE5A 2PFMA 3UNVA 4CQ5A 1J3UA 2QGAB 4BAAA 3RD8A 4ADLA 1TJUA 2HVGA 3R6VA 1U16A 1EB4A 5EYTA 1B8FA 3C8TA 3BHGA 2O6YA 2VD6A 2O7BA 1K62A 1GKJA 1AUWA 2O78A 2NYFA 1T6JA 1GK3A 1GKMA 4MX2A 4HGVA 4EEIA 1TJ7A 5HW2A 4V2QA 4C6GA 3TV2A 1C3UA 1FURA 3E04A 1TJVA 3KDYA 4APAA 4C5RA 2X75A 1TJWA 5EYVA 2PTQA 2OHYA 1HY1A 3NO9A 3CZOA 4APBA 1HY0A 3OCEA 1VDKA 3NZ4A 1T6PA 3GZHA 1GK2A 1W27A 2J91A 2E9FA 4NLEA 2NYNA 1U15A 3RRPA 3QBPA 1I0AA 1YFMA 3R6YA 1FUOA 1Y2MA 5F92A 1XWOA 4EFCA 2RJSA 1K7WA 3KDZA 2O7EA 5F91A 4V2RA 2YIIA 1DOFA 2PTSA 3GTDA 1Q5NA 1DCNA 4FFXA 4C5SA 1C3CA 1FUPA 4BABA 4ADMA 2PTRA 2QVEA 2O7FA 1YISA 3R6QA 4NSLA 2RJRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FLC A;  4C5U A;  2FUS A;  1YFE A;  1JSW A;  5D6B A;  1KQ7 A;  2O7D A;  1FUQ A;  3OCF A;  1RE5 A;  2PFM A;  3UNV A;  4CQ5 A;  1J3U A;  2QGA B;  4BAA A;  3RD8 A;  4ADL A;  1TJU A;  2HVG A;  3R6V A;  1U16 A;  1EB4 A;  5EYT A;  1B8F A;  3C8T A;  3BHG A;  2O6Y A;  2VD6 A;  2O7B A;  1K62 A;  1GKJ A;  1AUW A;  2O78 A;  2NYF A;  1T6J A;  1GK3 A;  1GKM A;  4MX2 A;  4HGV A;  4EEI A;  1TJ7 A;  5HW2 A;  4V2Q A;  4C6G A;  3TV2 A;  1C3U A;  1FUR A;  3E04 A;  1TJV A;  3KDY A;  4APA A;  4C5R A;  2X75 A;  1TJW A;  5EYV A;  2PTQ A;  2OHY A;  1HY1 A;  3NO9 A;  3CZO A;  4APB A;  1HY0 A;  3OCE A;  1VDK A;  3NZ4 A;  1T6P A;  3GZH A;  1GK2 A;  1W27 A;  2J91 A;  2E9F A;  4NLE A;  2NYN A;  1U15 A;  3RRP A;  3QBP A;  1I0A A;  1YFM A;  3R6Y A;  1FUO A;  1Y2M A;  5F92 A;  1XWO A;  4EFC A;  2RJS A;  1K7W A;  3KDZ A;  2O7E A;  5F91 A;  4V2R A;  2YII A;  1DOF A;  2PTS A;  3GTD A;  1Q5N A;  1DCN A;  4FFX A;  4C5S A;  1C3C A;  1FUP A;  4BAB A;  4ADM A;  2PTR A;  2QVE A;  2O7F A;  1YIS A;  3R6Q A;  4NSL A;  2RJR A; 
#chains in the Genus database with same CATH topology
 4FLC A;  4C5U A;  2FUS A;  1YFE A;  1JSW A;  5D6B A;  1KQ7 A;  2O7D A;  1FUQ A;  3OCF A;  5H8W A;  1RE5 A;  2PFM A;  3UNV A;  4CQ5 A;  1J3U A;  2QGA B;  4BAA A;  3RD8 A;  4ADL A;  1TJU A;  2HVG A;  3R6V A;  1U16 A;  1EB4 A;  5EYT A;  1XMD A;  1B8F A;  3C8T A;  3BHG A;  2O6Y A;  5M0I A;  2VD6 A;  2O7B A;  1K62 A;  1GKJ A;  1AUW A;  2O78 A;  2NYF A;  1T6J A;  1GK3 A;  1GKM A;  4MX2 A;  3CRV A;  4HGV A;  4EEI A;  1TJ7 A;  5HW2 A;  4V2Q A;  4C6G A;  3TV2 A;  1C3U A;  1FUR A;  3E04 A;  1TJV A;  3KDY A;  4APA A;  4C5R A;  2X75 A;  1TJW A;  5EYV A;  2PTQ A;  2OHY A;  1HY1 A;  3NO9 A;  3CZO A;  4APB A;  1HY0 A;  3OCE A;  1VDK A;  3NZ4 A;  1T6P A;  3GZH A;  2FEL A;  1XL8 A;  1GK2 A;  1W27 A;  2J91 A;  4WNL A;  2E9F A;  4NLE A;  2NYN A;  3CRW 1;  1U15 A;  3RRP A;  2VL7 A;  3QBP A;  1I0A A;  1YFM A;  3R6Y A;  1FUO A;  1Y2M A;  5F92 A;  1XWO A;  4EFC A;  2RJS A;  2FEN A;  1K7W A;  3KDZ A;  2O7E A;  5F91 A;  4A15 A;  4V2R A;  2YII A;  1XLY A;  1XMC A;  2VSF A;  5M0J A;  1DOF A;  2PTS A;  3GTD A;  1Q5N A;  1DCN A;  4FFX A;  1XL7 A;  4C5S A;  1C3C A;  1FUP A;  4BAB A;  4ADM A;  2PTR A;  2QVE A;  2O7F A;  1YIS A;  3R6Q A;  4NSL A;  2RJR A; 
#chains in the Genus database with same CATH homology
 4FLC A;  4C5U A;  2FUS A;  1YFE A;  1JSW A;  5D6B A;  1KQ7 A;  2O7D A;  1FUQ A;  3OCF A;  1RE5 A;  2PFM A;  3UNV A;  4CQ5 A;  1J3U A;  2QGA B;  4BAA A;  3RD8 A;  4ADL A;  1TJU A;  2HVG A;  3R6V A;  1U16 A;  1EB4 A;  5EYT A;  1B8F A;  3C8T A;  3BHG A;  2O6Y A;  2VD6 A;  2O7B A;  1K62 A;  1GKJ A;  1AUW A;  2O78 A;  2NYF A;  1T6J A;  1GK3 A;  1GKM A;  4MX2 A;  4HGV A;  4EEI A;  1TJ7 A;  5HW2 A;  4V2Q A;  4C6G A;  3TV2 A;  1C3U A;  1FUR A;  3E04 A;  1TJV A;  3KDY A;  4APA A;  4C5R A;  2X75 A;  1TJW A;  5EYV A;  2PTQ A;  2OHY A;  1HY1 A;  3NO9 A;  3CZO A;  4APB A;  1HY0 A;  3OCE A;  1VDK A;  3NZ4 A;  1T6P A;  3GZH A;  1GK2 A;  1W27 A;  2J91 A;  2E9F A;  4NLE A;  2NYN A;  1U15 A;  3RRP A;  3QBP A;  1I0A A;  1YFM A;  3R6Y A;  1FUO A;  1Y2M A;  5F92 A;  1XWO A;  4EFC A;  2RJS A;  1K7W A;  3KDZ A;  2O7E A;  5F91 A;  4V2R A;  2YII A;  1DOF A;  2PTS A;  3GTD A;  1Q5N A;  1DCN A;  4FFX A;  4C5S A;  1C3C A;  1FUP A;  4BAB A;  4ADM A;  2PTR A;  2QVE A;  2O7F A;  1YIS A;  3R6Q A;  4NSL A;  2RJR A; 
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