2O6YA

Tyrosine ammonia-lyase from rhodobacter sphaeroides
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Putative histidine ammonia-lyase
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o6yA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o6yA02
4C5RA 4ADMA 4NLEA 3KDYA 3QBPA 1GK2A 1T6PA 4CQ5A 4V2RA 4HGVA 1K7WA 5EYTA 1I0AA 1TJ7A 3TV2A 4C5SA 2OHYA 2E9FA 4V2QA 1EB4A 3R6QA 1RE5A 3OCEA 2O7FA 1GK3A 1TJVA 2PTRA 1T6JA 5EYVA 2FUSA 1HY1A 4MX2A 1DCNA 3C8TA 1Y2MA 3OCFA 1HY0A 2O7EA 1FUPA 1Q5NA 2X75A 1AUWA 1KQ7A 2QVEA 1YFEA 1B8FA 5F92A 1C3UA 2J91A 1TJWA 2O7DA 1FUOA 4FFXA 1GKMA 3E04A 4C6GA 2PFMA 4FLCA 1GKJA 1C3CA 3R6VA 2O78A 3GTDA 2NYNA 5HW2A 4APBA 1YISA 1U16A 4BAAA 4EFCA 3UNVA 5F91A 4NSLA 1JSWA 3RRPA 1FURA 4APAA 4ADLA 2RJRA 5D6BA 3RD8A 2VD6A 1DOFA 2O7BA 3NO9A 3NZ4A 3BHGA 2O6YA 2RJSA 3R6YA 4BABA 1K62A 3CZOA 2HVGA 1J3UA 2PTQA 3KDZA 1W27A 4C5UA 1XWOA 2YIIA 2NYFA 4EEIA 1VDKA 1TJUA 3GZHA 1FUQA 1U15A 1YFMA 2QGAB 2PTSA
chains in the Genus database with same CATH superfamily
4C5RA 4NLEA 4ADMA 3KDYA 3QBPA 3CRW1 1GK2A 1T6PA 5M0IA 4CQ5A 4V2RA 4HGVA 1K7WA 5EYTA 1I0AA 1TJ7A 3TV2A 4C5SA 2OHYA 2E9FA 4V2QA 4WNLA 1EB4A 3R6QA 1RE5A 3OCEA 2O7FA 1GK3A 1TJVA 2PTRA 1T6JA 5EYVA 2FUSA 1HY1A 4MX2A 1DCNA 3C8TA 1Y2MA 3OCFA 1HY0A 2O7EA 1FUPA 1Q5NA 2X75A 1AUWA 5H8WA 1KQ7A 2QVEA 1YFEA 1B8FA 5F92A 2FELA 1C3UA 1XL8A 2J91A 1TJWA 1XL7A 2O7DA 2VSFA 1FUOA 4FFXA 4A15A 1GKMA 3E04A 4C6GA 2PFMA 4FLCA 1GKJA 1C3CA 3R6VA 2O78A 3GTDA 2NYNA 5HW2A 4APBA 1YISA 1U16A 4BAAA 4EFCA 3CRVA 3UNVA 5F91A 4NSLA 1JSWA 3RRPA 2FENA 1FURA 4APAA 2VL7A 4ADLA 2RJRA 5D6BA 3RD8A 2VD6A 1DOFA 2O7BA 3NO9A 3NZ4A 5M0JA 3BHGA 1XLYA 2O6YA 2RJSA 3R6YA 4BABA 1K62A 3CZOA 2HVGA 1XMCA 1J3UA 1XMDA 2PTQA 3KDZA 1W27A 4C5UA 1XWOA 2YIIA 2NYFA 4EEIA 1VDKA 1TJUA 3GZHA 1FUQA 1U15A 1YFMA 2QGAB 2PTSA
chains in the Genus database with same CATH topology
4C5RA 4ADMA 4NLEA 3KDYA 3QBPA 1GK2A 1T6PA 4CQ5A 4V2RA 4HGVA 1K7WA 5EYTA 1I0AA 1TJ7A 3TV2A 4C5SA 2OHYA 2E9FA 4V2QA 1EB4A 3R6QA 1RE5A 3OCEA 2O7FA 1GK3A 1TJVA 2PTRA 1T6JA 5EYVA 2FUSA 1HY1A 4MX2A 1DCNA 3C8TA 1Y2MA 3OCFA 1HY0A 2O7EA 1FUPA 1Q5NA 2X75A 1AUWA 1KQ7A 2QVEA 1YFEA 1B8FA 5F92A 1C3UA 2J91A 1TJWA 2O7DA 1FUOA 4FFXA 1GKMA 3E04A 4C6GA 2PFMA 4FLCA 1GKJA 1C3CA 3R6VA 2O78A 3GTDA 2NYNA 5HW2A 4APBA 1YISA 1U16A 4BAAA 4EFCA 3UNVA 5F91A 4NSLA 1JSWA 3RRPA 1FURA 4APAA 4ADLA 2RJRA 5D6BA 3RD8A 2VD6A 1DOFA 2O7BA 3NO9A 3NZ4A 3BHGA 2O6YA 2RJSA 3R6YA 4BABA 1K62A 3CZOA 2HVGA 1J3UA 2PTQA 3KDZA 1W27A 4C5UA 1XWOA 2YIIA 2NYFA 4EEIA 1VDKA 1TJUA 3GZHA 1FUQA 1U15A 1YFMA 2QGAB 2PTSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5R A;  4ADM A;  4NLE A;  3KDY A;  3QBP A;  1GK2 A;  1T6P A;  4CQ5 A;  4V2R A;  4HGV A;  1K7W A;  5EYT A;  1I0A A;  1TJ7 A;  3TV2 A;  4C5S A;  2OHY A;  2E9F A;  4V2Q A;  1EB4 A;  3R6Q A;  1RE5 A;  3OCE A;  2O7F A;  1GK3 A;  1TJV A;  2PTR A;  1T6J A;  5EYV A;  2FUS A;  1HY1 A;  4MX2 A;  1DCN A;  3C8T A;  1Y2M A;  3OCF A;  1HY0 A;  2O7E A;  1FUP A;  1Q5N A;  2X75 A;  1AUW A;  1KQ7 A;  2QVE A;  1YFE A;  1B8F A;  5F92 A;  1C3U A;  2J91 A;  1TJW A;  2O7D A;  1FUO A;  4FFX A;  1GKM A;  3E04 A;  4C6G A;  2PFM A;  4FLC A;  1GKJ A;  1C3C A;  3R6V A;  2O78 A;  3GTD A;  2NYN A;  5HW2 A;  4APB A;  1YIS A;  1U16 A;  4BAA A;  4EFC A;  3UNV A;  5F91 A;  4NSL A;  1JSW A;  3RRP A;  1FUR A;  4APA A;  4ADL A;  2RJR A;  5D6B A;  3RD8 A;  2VD6 A;  1DOF A;  2O7B A;  3NO9 A;  3NZ4 A;  3BHG A;  2O6Y A;  2RJS A;  3R6Y A;  4BAB A;  1K62 A;  3CZO A;  2HVG A;  1J3U A;  2PTQ A;  3KDZ A;  1W27 A;  4C5U A;  1XWO A;  2YII A;  2NYF A;  4EEI A;  1VDK A;  1TJU A;  3GZH A;  1FUQ A;  1U15 A;  1YFM A;  2QGA B;  2PTS A; 
#chains in the Genus database with same CATH topology
 4C5R A;  4NLE A;  4ADM A;  3KDY A;  3QBP A;  3CRW 1;  1GK2 A;  1T6P A;  5M0I A;  4CQ5 A;  4V2R A;  4HGV A;  1K7W A;  5EYT A;  1I0A A;  1TJ7 A;  3TV2 A;  4C5S A;  2OHY A;  2E9F A;  4V2Q A;  4WNL A;  1EB4 A;  3R6Q A;  1RE5 A;  3OCE A;  2O7F A;  1GK3 A;  1TJV A;  2PTR A;  1T6J A;  5EYV A;  2FUS A;  1HY1 A;  4MX2 A;  1DCN A;  3C8T A;  1Y2M A;  3OCF A;  1HY0 A;  2O7E A;  1FUP A;  1Q5N A;  2X75 A;  1AUW A;  5H8W A;  1KQ7 A;  2QVE A;  1YFE A;  1B8F A;  5F92 A;  2FEL A;  1C3U A;  1XL8 A;  2J91 A;  1TJW A;  1XL7 A;  2O7D A;  2VSF A;  1FUO A;  4FFX A;  4A15 A;  1GKM A;  3E04 A;  4C6G A;  2PFM A;  4FLC A;  1GKJ A;  1C3C A;  3R6V A;  2O78 A;  3GTD A;  2NYN A;  5HW2 A;  4APB A;  1YIS A;  1U16 A;  4BAA A;  4EFC A;  3CRV A;  3UNV A;  5F91 A;  4NSL A;  1JSW A;  3RRP A;  2FEN A;  1FUR A;  4APA A;  2VL7 A;  4ADL A;  2RJR A;  5D6B A;  3RD8 A;  2VD6 A;  1DOF A;  2O7B A;  3NO9 A;  3NZ4 A;  5M0J A;  3BHG A;  1XLY A;  2O6Y A;  2RJS A;  3R6Y A;  4BAB A;  1K62 A;  3CZO A;  2HVG A;  1XMC A;  1J3U A;  1XMD A;  2PTQ A;  3KDZ A;  1W27 A;  4C5U A;  1XWO A;  2YII A;  2NYF A;  4EEI A;  1VDK A;  1TJU A;  3GZH A;  1FUQ A;  1U15 A;  1YFM A;  2QGA B;  2PTS A; 
#chains in the Genus database with same CATH homology
 4C5R A;  4ADM A;  4NLE A;  3KDY A;  3QBP A;  1GK2 A;  1T6P A;  4CQ5 A;  4V2R A;  4HGV A;  1K7W A;  5EYT A;  1I0A A;  1TJ7 A;  3TV2 A;  4C5S A;  2OHY A;  2E9F A;  4V2Q A;  1EB4 A;  3R6Q A;  1RE5 A;  3OCE A;  2O7F A;  1GK3 A;  1TJV A;  2PTR A;  1T6J A;  5EYV A;  2FUS A;  1HY1 A;  4MX2 A;  1DCN A;  3C8T A;  1Y2M A;  3OCF A;  1HY0 A;  2O7E A;  1FUP A;  1Q5N A;  2X75 A;  1AUW A;  1KQ7 A;  2QVE A;  1YFE A;  1B8F A;  5F92 A;  1C3U A;  2J91 A;  1TJW A;  2O7D A;  1FUO A;  4FFX A;  1GKM A;  3E04 A;  4C6G A;  2PFM A;  4FLC A;  1GKJ A;  1C3C A;  3R6V A;  2O78 A;  3GTD A;  2NYN A;  5HW2 A;  4APB A;  1YIS A;  1U16 A;  4BAA A;  4EFC A;  3UNV A;  5F91 A;  4NSL A;  1JSW A;  3RRP A;  1FUR A;  4APA A;  4ADL A;  2RJR A;  5D6B A;  3RD8 A;  2VD6 A;  1DOF A;  2O7B A;  3NO9 A;  3NZ4 A;  3BHG A;  2O6Y A;  2RJS A;  3R6Y A;  4BAB A;  1K62 A;  3CZO A;  2HVG A;  1J3U A;  2PTQ A;  3KDZ A;  1W27 A;  4C5U A;  1XWO A;  2YII A;  2NYF A;  4EEI A;  1VDK A;  1TJU A;  3GZH A;  1FUQ A;  1U15 A;  1YFM A;  2QGA B;  2PTS A; 
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