2O6YA

Tyrosine ammonia-lyase from rhodobacter sphaeroides
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o6yA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o6yA02
1FUQA 3GTDA 3NZ4A 1TJVA 2PTRA 1GKJA 2QVEA 2FUSA 1J3UA 4V2QA 2O7FA 1XWOA 3OCEA 2E9FA 1VDKA 4C6GA 1KQ7A 3QBPA 5EYTA 3UNVA 1FUPA 1JSWA 4HGVA 1U15A 3C8TA 1GK3A 1GK2A 1TJ7A 2PTSA 4C5RA 1Y2MA 3CZOA 2O7EA 3NO9A 2X75A 1B8FA 3TV2A 5HW2A 2PFMA 4FFXA 4CQ5A 2NYNA 2OHYA 2O78A 2O7DA 1TJUA 2QGAB 2RJSA 4MX2A 1GKMA 1Q5NA 1YFMA 4V2RA 1FURA 5F91A 2NYFA 1C3UA 3R6QA 4FLCA 4EFCA 4C5UA 3KDYA 4NLEA 5D6BA 1DOFA 1W27A 4APAA 1I0AA 1T6JA 4C5SA 1U16A 3GZHA 1RE5A 1T6PA 3KDZA 4BAAA 2PTQA 4NSLA 4APBA 4ADLA 1HY0A 1YFEA 1DCNA 1FUOA 1TJWA 2YIIA 4EEIA 2O6YA 2RJRA 1K62A 3OCFA 2VD6A 1YISA 1K7WA 4ADMA 1AUWA 5EYVA 3RRPA 3R6YA 4BABA 2J91A 3RD8A 5F92A 3BHGA 1HY1A 3R6VA 3E04A 2HVGA 1C3CA 2O7BA 1EB4A
chains in the Genus database with same CATH superfamily
1FUQA 3GTDA 3NZ4A 1TJVA 2PTRA 1GKJA 5H8WA 2QVEA 2FUSA 1J3UA 4V2QA 2O7FA 1XWOA 3OCEA 2E9FA 1VDKA 4C6GA 1KQ7A 3QBPA 5EYTA 3UNVA 1FUPA 2VL7A 5M0JA 1JSWA 4HGVA 3CRVA 1U15A 3C8TA 1GK3A 1GK2A 1TJ7A 2PTSA 4C5RA 1Y2MA 3CZOA 2O7EA 3NO9A 2X75A 1B8FA 3TV2A 5HW2A 2PFMA 4FFXA 4CQ5A 1XL8A 2NYNA 2OHYA 2O78A 2O7DA 2VSFA 1TJUA 2QGAB 2RJSA 4MX2A 1GKMA 1Q5NA 1YFMA 4V2RA 1FURA 5F91A 2NYFA 1C3UA 3R6QA 4FLCA 4EFCA 4C5UA 3KDYA 4NLEA 5D6BA 1DOFA 1W27A 4APAA 1I0AA 1T6JA 4C5SA 1U16A 3GZHA 1RE5A 4WNLA 1T6PA 3KDZA 4BAAA 2PTQA 4NSLA 1XMCA 4APBA 4ADLA 1HY0A 1XMDA 1YFEA 1DCNA 2FENA 1FUOA 1TJWA 2YIIA 1XLYA 4EEIA 2FELA 2O6YA 2RJRA 1K62A 3OCFA 4A15A 2VD6A 1YISA 1K7WA 4ADMA 1AUWA 5EYVA 3RRPA 3R6YA 4BABA 2J91A 3RD8A 5F92A 3BHGA 1HY1A 3R6VA 3E04A 2HVGA 1C3CA 1XL7A 2O7BA 1EB4A 3CRW1 5M0IA
chains in the Genus database with same CATH topology
1FUQA 3GTDA 3NZ4A 1TJVA 2PTRA 1GKJA 2QVEA 2FUSA 1J3UA 4V2QA 2O7FA 1XWOA 3OCEA 2E9FA 1VDKA 4C6GA 1KQ7A 3QBPA 5EYTA 3UNVA 1FUPA 1JSWA 4HGVA 1U15A 3C8TA 1GK3A 1GK2A 1TJ7A 2PTSA 4C5RA 1Y2MA 3CZOA 2O7EA 3NO9A 2X75A 1B8FA 3TV2A 5HW2A 2PFMA 4FFXA 4CQ5A 2NYNA 2OHYA 2O78A 2O7DA 1TJUA 2QGAB 2RJSA 4MX2A 1GKMA 1Q5NA 1YFMA 4V2RA 1FURA 5F91A 2NYFA 1C3UA 3R6QA 4FLCA 4EFCA 4C5UA 3KDYA 4NLEA 5D6BA 1DOFA 1W27A 4APAA 1I0AA 1T6JA 4C5SA 1U16A 3GZHA 1RE5A 1T6PA 3KDZA 4BAAA 2PTQA 4NSLA 4APBA 4ADLA 1HY0A 1YFEA 1DCNA 1FUOA 1TJWA 2YIIA 4EEIA 2O6YA 2RJRA 1K62A 3OCFA 2VD6A 1YISA 1K7WA 4ADMA 1AUWA 5EYVA 3RRPA 3R6YA 4BABA 2J91A 3RD8A 5F92A 3BHGA 1HY1A 3R6VA 3E04A 2HVGA 1C3CA 2O7BA 1EB4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FUQ A;  3GTD A;  3NZ4 A;  1TJV A;  2PTR A;  1GKJ A;  2QVE A;  2FUS A;  1J3U A;  4V2Q A;  2O7F A;  1XWO A;  3OCE A;  2E9F A;  1VDK A;  4C6G A;  1KQ7 A;  3QBP A;  5EYT A;  3UNV A;  1FUP A;  1JSW A;  4HGV A;  1U15 A;  3C8T A;  1GK3 A;  1GK2 A;  1TJ7 A;  2PTS A;  4C5R A;  1Y2M A;  3CZO A;  2O7E A;  3NO9 A;  2X75 A;  1B8F A;  3TV2 A;  5HW2 A;  2PFM A;  4FFX A;  4CQ5 A;  2NYN A;  2OHY A;  2O78 A;  2O7D A;  1TJU A;  2QGA B;  2RJS A;  4MX2 A;  1GKM A;  1Q5N A;  1YFM A;  4V2R A;  1FUR A;  5F91 A;  2NYF A;  1C3U A;  3R6Q A;  4FLC A;  4EFC A;  4C5U A;  3KDY A;  4NLE A;  5D6B A;  1DOF A;  1W27 A;  4APA A;  1I0A A;  1T6J A;  4C5S A;  1U16 A;  3GZH A;  1RE5 A;  1T6P A;  3KDZ A;  4BAA A;  2PTQ A;  4NSL A;  4APB A;  4ADL A;  1HY0 A;  1YFE A;  1DCN A;  1FUO A;  1TJW A;  2YII A;  4EEI A;  2O6Y A;  2RJR A;  1K62 A;  3OCF A;  2VD6 A;  1YIS A;  1K7W A;  4ADM A;  1AUW A;  5EYV A;  3RRP A;  3R6Y A;  4BAB A;  2J91 A;  3RD8 A;  5F92 A;  3BHG A;  1HY1 A;  3R6V A;  3E04 A;  2HVG A;  1C3C A;  2O7B A;  1EB4 A; 
#chains in the Genus database with same CATH topology
 1FUQ A;  3GTD A;  3NZ4 A;  1TJV A;  2PTR A;  1GKJ A;  5H8W A;  2QVE A;  2FUS A;  1J3U A;  4V2Q A;  2O7F A;  1XWO A;  3OCE A;  2E9F A;  1VDK A;  4C6G A;  1KQ7 A;  3QBP A;  5EYT A;  3UNV A;  1FUP A;  2VL7 A;  5M0J A;  1JSW A;  4HGV A;  3CRV A;  1U15 A;  3C8T A;  1GK3 A;  1GK2 A;  1TJ7 A;  2PTS A;  4C5R A;  1Y2M A;  3CZO A;  2O7E A;  3NO9 A;  2X75 A;  1B8F A;  3TV2 A;  5HW2 A;  2PFM A;  4FFX A;  4CQ5 A;  1XL8 A;  2NYN A;  2OHY A;  2O78 A;  2O7D A;  2VSF A;  1TJU A;  2QGA B;  2RJS A;  4MX2 A;  1GKM A;  1Q5N A;  1YFM A;  4V2R A;  1FUR A;  5F91 A;  2NYF A;  1C3U A;  3R6Q A;  4FLC A;  4EFC A;  4C5U A;  3KDY A;  4NLE A;  5D6B A;  1DOF A;  1W27 A;  4APA A;  1I0A A;  1T6J A;  4C5S A;  1U16 A;  3GZH A;  1RE5 A;  4WNL A;  1T6P A;  3KDZ A;  4BAA A;  2PTQ A;  4NSL A;  1XMC A;  4APB A;  4ADL A;  1HY0 A;  1XMD A;  1YFE A;  1DCN A;  2FEN A;  1FUO A;  1TJW A;  2YII A;  1XLY A;  4EEI A;  2FEL A;  2O6Y A;  2RJR A;  1K62 A;  3OCF A;  4A15 A;  2VD6 A;  1YIS A;  1K7W A;  4ADM A;  1AUW A;  5EYV A;  3RRP A;  3R6Y A;  4BAB A;  2J91 A;  3RD8 A;  5F92 A;  3BHG A;  1HY1 A;  3R6V A;  3E04 A;  2HVG A;  1C3C A;  1XL7 A;  2O7B A;  1EB4 A;  3CRW 1;  5M0I A; 
#chains in the Genus database with same CATH homology
 1FUQ A;  3GTD A;  3NZ4 A;  1TJV A;  2PTR A;  1GKJ A;  2QVE A;  2FUS A;  1J3U A;  4V2Q A;  2O7F A;  1XWO A;  3OCE A;  2E9F A;  1VDK A;  4C6G A;  1KQ7 A;  3QBP A;  5EYT A;  3UNV A;  1FUP A;  1JSW A;  4HGV A;  1U15 A;  3C8T A;  1GK3 A;  1GK2 A;  1TJ7 A;  2PTS A;  4C5R A;  1Y2M A;  3CZO A;  2O7E A;  3NO9 A;  2X75 A;  1B8F A;  3TV2 A;  5HW2 A;  2PFM A;  4FFX A;  4CQ5 A;  2NYN A;  2OHY A;  2O78 A;  2O7D A;  1TJU A;  2QGA B;  2RJS A;  4MX2 A;  1GKM A;  1Q5N A;  1YFM A;  4V2R A;  1FUR A;  5F91 A;  2NYF A;  1C3U A;  3R6Q A;  4FLC A;  4EFC A;  4C5U A;  3KDY A;  4NLE A;  5D6B A;  1DOF A;  1W27 A;  4APA A;  1I0A A;  1T6J A;  4C5S A;  1U16 A;  3GZH A;  1RE5 A;  1T6P A;  3KDZ A;  4BAA A;  2PTQ A;  4NSL A;  4APB A;  4ADL A;  1HY0 A;  1YFE A;  1DCN A;  1FUO A;  1TJW A;  2YII A;  4EEI A;  2O6Y A;  2RJR A;  1K62 A;  3OCF A;  2VD6 A;  1YIS A;  1K7W A;  4ADM A;  1AUW A;  5EYV A;  3RRP A;  3R6Y A;  4BAB A;  2J91 A;  3RD8 A;  5F92 A;  3BHG A;  1HY1 A;  3R6V A;  3E04 A;  2HVG A;  1C3C A;  2O7B A;  1EB4 A; 
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