2RJSA

Sgtam bound to substrate mimic
Total Genus 198
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
198
sequence length
526
structure length
525
Chain Sequence
b'PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
molecule keywords Tyrosine aminomutase
source organism Streptomyces globisporus
molecule tags Isomerase
total genus 198
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjsA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjsA02
1GKJA 3TV2A 1GK2A 4C6GA 4APAA 2RJRA 4C5SA 4NSLA 1K62A 1VDKA 5EYVA 3OCEA 2QGAB 2RJSA 3RD8A 1C3UA 5EYTA 1HY1A 4FLCA 5HW2A 5F91A 1YFMA 2FUSA 4FFXA 4MX2A 2QVEA 2YIIA 4V2RA 1Y2MA 1TJUA 3NZ4A 1RE5A 1FUPA 4ADLA 1YFEA 3KDZA 1FURA 1EB4A 1T6JA 2O7BA 1GK3A 4APBA 1GKMA 3OCFA 4BAAA 2O78A 4ADMA 1YISA 1AUWA 4HGVA 5D6BA 1DOFA 2HVGA 5F92A 1KQ7A 1DCNA 2O7EA 4NLEA 1FUQA 2NYNA 1HY0A 1TJVA 1B8FA 1I0AA 1T6PA 1K7WA 2VD6A 3C8TA 2PTSA 3KDYA 1C3CA 3GTDA 2J91A 1W27A 2O7DA 1JSWA 2E9FA 3E04A 1U15A 4C5UA 4C5RA 4EFCA 3QBPA 3CZOA 3RRPA 2O6YA 3NO9A 2X75A 4V2QA 4CQ5A 3R6YA 4EEIA 2PFMA 1FUOA 1TJWA 1J3UA 2PTQA 2O7FA 1TJ7A 3UNVA 3R6VA 4BABA 3BHGA 1Q5NA 3R6QA 3GZHA 2NYFA 1XWOA 2PTRA 1U16A 2OHYA
chains in the Genus database with same CATH superfamily
1GKJA 3TV2A 1GK2A 4C6GA 4APAA 2RJRA 4C5SA 4NSLA 1K62A 1XMCA 4WNLA 1VDKA 5EYVA 3OCEA 2QGAB 2RJSA 3RD8A 1C3UA 5EYTA 1HY1A 2VL7A 4FLCA 5HW2A 5F91A 1YFMA 2FUSA 4FFXA 4MX2A 2QVEA 2YIIA 4V2RA 1Y2MA 1TJUA 3NZ4A 4A15A 1RE5A 1XLYA 1FUPA 4ADLA 1YFEA 3KDZA 1FURA 1EB4A 1T6JA 2O7BA 1GK3A 4APBA 1GKMA 3OCFA 4BAAA 2O78A 1XMDA 4ADMA 1YISA 1AUWA 4HGVA 5D6BA 1DOFA 2HVGA 5F92A 2VSFA 1KQ7A 1DCNA 2O7EA 4NLEA 1FUQA 5H8WA 2NYNA 3CRW1 5M0IA 1HY0A 1TJVA 1XL8A 1B8FA 1I0AA 1T6PA 1K7WA 2VD6A 3C8TA 2PTSA 2FENA 5M0JA 3KDYA 1C3CA 3GTDA 2J91A 1W27A 2E9FA 1JSWA 2O7DA 3E04A 1XL7A 1U15A 4C5UA 4C5RA 4EFCA 3QBPA 3CZOA 3RRPA 2O6YA 3NO9A 2X75A 3CRVA 2FELA 4V2QA 4CQ5A 3R6YA 4EEIA 2PFMA 1FUOA 1TJWA 1J3UA 2PTQA 2O7FA 1TJ7A 3UNVA 3R6VA 4BABA 3BHGA 1Q5NA 3R6QA 3GZHA 2NYFA 1XWOA 2PTRA 1U16A 2OHYA
chains in the Genus database with same CATH topology
1GKJA 3TV2A 1GK2A 4C6GA 4APAA 2RJRA 4C5SA 4NSLA 1K62A 1VDKA 5EYVA 3OCEA 2QGAB 2RJSA 3RD8A 1C3UA 5EYTA 1HY1A 4FLCA 5HW2A 5F91A 1YFMA 2FUSA 4FFXA 4MX2A 2QVEA 2YIIA 4V2RA 1Y2MA 1TJUA 3NZ4A 1RE5A 1FUPA 4ADLA 1YFEA 3KDZA 1FURA 1EB4A 1T6JA 2O7BA 1GK3A 4APBA 1GKMA 3OCFA 4BAAA 2O78A 4ADMA 1YISA 1AUWA 4HGVA 5D6BA 1DOFA 2HVGA 5F92A 1KQ7A 1DCNA 2O7EA 4NLEA 1FUQA 2NYNA 1HY0A 1TJVA 1B8FA 1I0AA 1T6PA 1K7WA 2VD6A 3C8TA 2PTSA 3KDYA 1C3CA 3GTDA 2J91A 1W27A 2O7DA 1JSWA 2E9FA 3E04A 1U15A 4C5UA 4C5RA 4EFCA 3QBPA 3CZOA 3RRPA 2O6YA 3NO9A 2X75A 4V2QA 4CQ5A 3R6YA 4EEIA 2PFMA 1FUOA 1TJWA 1J3UA 2PTQA 2O7FA 1TJ7A 3UNVA 3R6VA 4BABA 3BHGA 1Q5NA 3R6QA 3GZHA 2NYFA 1XWOA 2PTRA 1U16A 2OHYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKJ A;  3TV2 A;  1GK2 A;  4C6G A;  4APA A;  2RJR A;  4C5S A;  4NSL A;  1K62 A;  1VDK A;  5EYV A;  3OCE A;  2QGA B;  2RJS A;  3RD8 A;  1C3U A;  5EYT A;  1HY1 A;  4FLC A;  5HW2 A;  5F91 A;  1YFM A;  2FUS A;  4FFX A;  4MX2 A;  2QVE A;  2YII A;  4V2R A;  1Y2M A;  1TJU A;  3NZ4 A;  1RE5 A;  1FUP A;  4ADL A;  1YFE A;  3KDZ A;  1FUR A;  1EB4 A;  1T6J A;  2O7B A;  1GK3 A;  4APB A;  1GKM A;  3OCF A;  4BAA A;  2O78 A;  4ADM A;  1YIS A;  1AUW A;  4HGV A;  5D6B A;  1DOF A;  2HVG A;  5F92 A;  1KQ7 A;  1DCN A;  2O7E A;  4NLE A;  1FUQ A;  2NYN A;  1HY0 A;  1TJV A;  1B8F A;  1I0A A;  1T6P A;  1K7W A;  2VD6 A;  3C8T A;  2PTS A;  3KDY A;  1C3C A;  3GTD A;  2J91 A;  1W27 A;  2O7D A;  1JSW A;  2E9F A;  3E04 A;  1U15 A;  4C5U A;  4C5R A;  4EFC A;  3QBP A;  3CZO A;  3RRP A;  2O6Y A;  3NO9 A;  2X75 A;  4V2Q A;  4CQ5 A;  3R6Y A;  4EEI A;  2PFM A;  1FUO A;  1TJW A;  1J3U A;  2PTQ A;  2O7F A;  1TJ7 A;  3UNV A;  3R6V A;  4BAB A;  3BHG A;  1Q5N A;  3R6Q A;  3GZH A;  2NYF A;  1XWO A;  2PTR A;  1U16 A;  2OHY A; 
#chains in the Genus database with same CATH topology
 1GKJ A;  3TV2 A;  1GK2 A;  4C6G A;  4APA A;  2RJR A;  4C5S A;  4NSL A;  1K62 A;  1XMC A;  4WNL A;  1VDK A;  5EYV A;  3OCE A;  2QGA B;  2RJS A;  3RD8 A;  1C3U A;  5EYT A;  1HY1 A;  2VL7 A;  4FLC A;  5HW2 A;  5F91 A;  1YFM A;  2FUS A;  4FFX A;  4MX2 A;  2QVE A;  2YII A;  4V2R A;  1Y2M A;  1TJU A;  3NZ4 A;  4A15 A;  1RE5 A;  1XLY A;  1FUP A;  4ADL A;  1YFE A;  3KDZ A;  1FUR A;  1EB4 A;  1T6J A;  2O7B A;  1GK3 A;  4APB A;  1GKM A;  3OCF A;  4BAA A;  2O78 A;  1XMD A;  4ADM A;  1YIS A;  1AUW A;  4HGV A;  5D6B A;  1DOF A;  2HVG A;  5F92 A;  2VSF A;  1KQ7 A;  1DCN A;  2O7E A;  4NLE A;  1FUQ A;  5H8W A;  2NYN A;  3CRW 1;  5M0I A;  1HY0 A;  1TJV A;  1XL8 A;  1B8F A;  1I0A A;  1T6P A;  1K7W A;  2VD6 A;  3C8T A;  2PTS A;  2FEN A;  5M0J A;  3KDY A;  1C3C A;  3GTD A;  2J91 A;  1W27 A;  2E9F A;  1JSW A;  2O7D A;  3E04 A;  1XL7 A;  1U15 A;  4C5U A;  4C5R A;  4EFC A;  3QBP A;  3CZO A;  3RRP A;  2O6Y A;  3NO9 A;  2X75 A;  3CRV A;  2FEL A;  4V2Q A;  4CQ5 A;  3R6Y A;  4EEI A;  2PFM A;  1FUO A;  1TJW A;  1J3U A;  2PTQ A;  2O7F A;  1TJ7 A;  3UNV A;  3R6V A;  4BAB A;  3BHG A;  1Q5N A;  3R6Q A;  3GZH A;  2NYF A;  1XWO A;  2PTR A;  1U16 A;  2OHY A; 
#chains in the Genus database with same CATH homology
 1GKJ A;  3TV2 A;  1GK2 A;  4C6G A;  4APA A;  2RJR A;  4C5S A;  4NSL A;  1K62 A;  1VDK A;  5EYV A;  3OCE A;  2QGA B;  2RJS A;  3RD8 A;  1C3U A;  5EYT A;  1HY1 A;  4FLC A;  5HW2 A;  5F91 A;  1YFM A;  2FUS A;  4FFX A;  4MX2 A;  2QVE A;  2YII A;  4V2R A;  1Y2M A;  1TJU A;  3NZ4 A;  1RE5 A;  1FUP A;  4ADL A;  1YFE A;  3KDZ A;  1FUR A;  1EB4 A;  1T6J A;  2O7B A;  1GK3 A;  4APB A;  1GKM A;  3OCF A;  4BAA A;  2O78 A;  4ADM A;  1YIS A;  1AUW A;  4HGV A;  5D6B A;  1DOF A;  2HVG A;  5F92 A;  1KQ7 A;  1DCN A;  2O7E A;  4NLE A;  1FUQ A;  2NYN A;  1HY0 A;  1TJV A;  1B8F A;  1I0A A;  1T6P A;  1K7W A;  2VD6 A;  3C8T A;  2PTS A;  3KDY A;  1C3C A;  3GTD A;  2J91 A;  1W27 A;  2O7D A;  1JSW A;  2E9F A;  3E04 A;  1U15 A;  4C5U A;  4C5R A;  4EFC A;  3QBP A;  3CZO A;  3RRP A;  2O6Y A;  3NO9 A;  2X75 A;  4V2Q A;  4CQ5 A;  3R6Y A;  4EEI A;  2PFM A;  1FUO A;  1TJW A;  1J3U A;  2PTQ A;  2O7F A;  1TJ7 A;  3UNV A;  3R6V A;  4BAB A;  3BHG A;  1Q5N A;  3R6Q A;  3GZH A;  2NYF A;  1XWO A;  2PTR A;  1U16 A;  2OHY A; 
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