2RJSA

Sgtam bound to substrate mimic
Total Genus 198
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
198
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Tyrosine aminomutase
publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Isomerase
total genus 198
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjsA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjsA02
1DOFA 2O7BA 4MX2A 4FFXA 5F91A 3GTDA 4ADLA 1GK2A 1JSWA 4ADMA 1YFEA 3OCFA 1DCNA 3R6YA 2NYNA 4C6GA 4EEIA 1K7WA 1K62A 4APAA 2O6YA 5D6BA 1XWOA 4APBA 4V2RA 1C3UA 1RE5A 3GZHA 4BABA 1U16A 3KDYA 3RRPA 1KQ7A 4C5UA 1FURA 3CZOA 3RD8A 3TV2A 1FUQA 1C3CA 1YISA 3NZ4A 3OCEA 1TJWA 4CQ5A 3BHGA 1EB4A 1T6JA 2PTSA 2PTRA 2QGAB 2O7FA 2NYFA 2RJSA 1YFMA 2QVEA 1GKMA 5F92A 1TJUA 2O7DA 1FUPA 4BAAA 4C5SA 3UNVA 4HGVA 1GKJA 1I0AA 4NSLA 3NO9A 3R6VA 4NLEA 3R6QA 1TJ7A 2VD6A 3C8TA 2E9FA 2O7EA 1FUOA 2PTQA 2OHYA 2PFMA 2YIIA 3E04A 2RJRA 5EYTA 4C5RA 1W27A 1AUWA 1VDKA 5HW2A 2J91A 2O78A 3KDZA 1TJVA 1HY1A 1T6PA 1U15A 2X75A 2FUSA 3QBPA 1J3UA 1B8FA 4FLCA 4V2QA 4EFCA 1Y2MA 1GK3A 2HVGA 5EYVA 1HY0A 1Q5NA
chains in the Genus database with same CATH superfamily
1DOFA 2O7BA 4MX2A 4FFXA 5F91A 3GTDA 4ADLA 1GK2A 1JSWA 5M0IA 4ADMA 1YFEA 3OCFA 1DCNA 3R6YA 2FENA 2NYNA 4C6GA 4EEIA 4A15A 1K7WA 1K62A 4APAA 2O6YA 5D6BA 1XWOA 4APBA 4V2RA 1C3UA 1RE5A 3GZHA 4BABA 1U16A 3KDYA 3RRPA 3CRVA 1KQ7A 4C5UA 1FURA 3CZOA 1XLYA 3RD8A 3TV2A 1FUQA 1C3CA 1YISA 3NZ4A 3OCEA 1TJWA 4CQ5A 3BHGA 1EB4A 1T6JA 1XL7A 2PTSA 2PTRA 2QGAB 2O7FA 2NYFA 2RJSA 1YFMA 2QVEA 1XMCA 1GKMA 5F92A 1TJUA 4WNLA 2O7DA 1FUPA 4BAAA 4C5SA 3CRW1 3UNVA 4HGVA 1GKJA 1I0AA 4NSLA 3NO9A 4NLEA 3R6VA 3R6QA 1TJ7A 2VD6A 3C8TA 2E9FA 2O7EA 1FUOA 2PTQA 5M0JA 2OHYA 2PFMA 2YIIA 3E04A 1XMDA 2RJRA 5EYTA 2FELA 4C5RA 1W27A 5H8WA 1AUWA 1VDKA 5HW2A 2J91A 2O78A 3KDZA 1TJVA 1HY1A 1T6PA 1U15A 2X75A 2FUSA 3QBPA 2VSFA 1J3UA 1B8FA 4FLCA 4V2QA 4EFCA 1Y2MA 1GK3A 2HVGA 5EYVA 1HY0A 1XL8A 1Q5NA 2VL7A
chains in the Genus database with same CATH topology
1DOFA 2O7BA 4MX2A 4FFXA 5F91A 3GTDA 4ADLA 1GK2A 1JSWA 4ADMA 1YFEA 3OCFA 1DCNA 3R6YA 2NYNA 4C6GA 4EEIA 1K7WA 1K62A 4APAA 2O6YA 5D6BA 1XWOA 4APBA 4V2RA 1C3UA 1RE5A 3GZHA 4BABA 1U16A 3KDYA 3RRPA 1KQ7A 4C5UA 1FURA 3CZOA 3RD8A 3TV2A 1FUQA 1C3CA 1YISA 3NZ4A 3OCEA 1TJWA 4CQ5A 3BHGA 1EB4A 1T6JA 2PTSA 2PTRA 2QGAB 2O7FA 2NYFA 2RJSA 1YFMA 2QVEA 1GKMA 5F92A 1TJUA 2O7DA 1FUPA 4BAAA 4C5SA 3UNVA 4HGVA 1GKJA 1I0AA 4NSLA 3NO9A 3R6VA 4NLEA 3R6QA 1TJ7A 2VD6A 3C8TA 2E9FA 2O7EA 1FUOA 2PTQA 2OHYA 2PFMA 2YIIA 3E04A 2RJRA 5EYTA 4C5RA 1W27A 1AUWA 1VDKA 5HW2A 2J91A 2O78A 3KDZA 1TJVA 1HY1A 1T6PA 1U15A 2X75A 2FUSA 3QBPA 1J3UA 1B8FA 4FLCA 4V2QA 4EFCA 1Y2MA 1GK3A 2HVGA 5EYVA 1HY0A 1Q5NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DOF A;  2O7B A;  4MX2 A;  4FFX A;  5F91 A;  3GTD A;  4ADL A;  1GK2 A;  1JSW A;  4ADM A;  1YFE A;  3OCF A;  1DCN A;  3R6Y A;  2NYN A;  4C6G A;  4EEI A;  1K7W A;  1K62 A;  4APA A;  2O6Y A;  5D6B A;  1XWO A;  4APB A;  4V2R A;  1C3U A;  1RE5 A;  3GZH A;  4BAB A;  1U16 A;  3KDY A;  3RRP A;  1KQ7 A;  4C5U A;  1FUR A;  3CZO A;  3RD8 A;  3TV2 A;  1FUQ A;  1C3C A;  1YIS A;  3NZ4 A;  3OCE A;  1TJW A;  4CQ5 A;  3BHG A;  1EB4 A;  1T6J A;  2PTS A;  2PTR A;  2QGA B;  2O7F A;  2NYF A;  2RJS A;  1YFM A;  2QVE A;  1GKM A;  5F92 A;  1TJU A;  2O7D A;  1FUP A;  4BAA A;  4C5S A;  3UNV A;  4HGV A;  1GKJ A;  1I0A A;  4NSL A;  3NO9 A;  3R6V A;  4NLE A;  3R6Q A;  1TJ7 A;  2VD6 A;  3C8T A;  2E9F A;  2O7E A;  1FUO A;  2PTQ A;  2OHY A;  2PFM A;  2YII A;  3E04 A;  2RJR A;  5EYT A;  4C5R A;  1W27 A;  1AUW A;  1VDK A;  5HW2 A;  2J91 A;  2O78 A;  3KDZ A;  1TJV A;  1HY1 A;  1T6P A;  1U15 A;  2X75 A;  2FUS A;  3QBP A;  1J3U A;  1B8F A;  4FLC A;  4V2Q A;  4EFC A;  1Y2M A;  1GK3 A;  2HVG A;  5EYV A;  1HY0 A;  1Q5N A; 
#chains in the Genus database with same CATH topology
 1DOF A;  2O7B A;  4MX2 A;  4FFX A;  5F91 A;  3GTD A;  4ADL A;  1GK2 A;  1JSW A;  5M0I A;  4ADM A;  1YFE A;  3OCF A;  1DCN A;  3R6Y A;  2FEN A;  2NYN A;  4C6G A;  4EEI A;  4A15 A;  1K7W A;  1K62 A;  4APA A;  2O6Y A;  5D6B A;  1XWO A;  4APB A;  4V2R A;  1C3U A;  1RE5 A;  3GZH A;  4BAB A;  1U16 A;  3KDY A;  3RRP A;  3CRV A;  1KQ7 A;  4C5U A;  1FUR A;  3CZO A;  1XLY A;  3RD8 A;  3TV2 A;  1FUQ A;  1C3C A;  1YIS A;  3NZ4 A;  3OCE A;  1TJW A;  4CQ5 A;  3BHG A;  1EB4 A;  1T6J A;  1XL7 A;  2PTS A;  2PTR A;  2QGA B;  2O7F A;  2NYF A;  2RJS A;  1YFM A;  2QVE A;  1XMC A;  1GKM A;  5F92 A;  1TJU A;  4WNL A;  2O7D A;  1FUP A;  4BAA A;  4C5S A;  3CRW 1;  3UNV A;  4HGV A;  1GKJ A;  1I0A A;  4NSL A;  3NO9 A;  4NLE A;  3R6V A;  3R6Q A;  1TJ7 A;  2VD6 A;  3C8T A;  2E9F A;  2O7E A;  1FUO A;  2PTQ A;  5M0J A;  2OHY A;  2PFM A;  2YII A;  3E04 A;  1XMD A;  2RJR A;  5EYT A;  2FEL A;  4C5R A;  1W27 A;  5H8W A;  1AUW A;  1VDK A;  5HW2 A;  2J91 A;  2O78 A;  3KDZ A;  1TJV A;  1HY1 A;  1T6P A;  1U15 A;  2X75 A;  2FUS A;  3QBP A;  2VSF A;  1J3U A;  1B8F A;  4FLC A;  4V2Q A;  4EFC A;  1Y2M A;  1GK3 A;  2HVG A;  5EYV A;  1HY0 A;  1XL8 A;  1Q5N A;  2VL7 A; 
#chains in the Genus database with same CATH homology
 1DOF A;  2O7B A;  4MX2 A;  4FFX A;  5F91 A;  3GTD A;  4ADL A;  1GK2 A;  1JSW A;  4ADM A;  1YFE A;  3OCF A;  1DCN A;  3R6Y A;  2NYN A;  4C6G A;  4EEI A;  1K7W A;  1K62 A;  4APA A;  2O6Y A;  5D6B A;  1XWO A;  4APB A;  4V2R A;  1C3U A;  1RE5 A;  3GZH A;  4BAB A;  1U16 A;  3KDY A;  3RRP A;  1KQ7 A;  4C5U A;  1FUR A;  3CZO A;  3RD8 A;  3TV2 A;  1FUQ A;  1C3C A;  1YIS A;  3NZ4 A;  3OCE A;  1TJW A;  4CQ5 A;  3BHG A;  1EB4 A;  1T6J A;  2PTS A;  2PTR A;  2QGA B;  2O7F A;  2NYF A;  2RJS A;  1YFM A;  2QVE A;  1GKM A;  5F92 A;  1TJU A;  2O7D A;  1FUP A;  4BAA A;  4C5S A;  3UNV A;  4HGV A;  1GKJ A;  1I0A A;  4NSL A;  3NO9 A;  3R6V A;  4NLE A;  3R6Q A;  1TJ7 A;  2VD6 A;  3C8T A;  2E9F A;  2O7E A;  1FUO A;  2PTQ A;  2OHY A;  2PFM A;  2YII A;  3E04 A;  2RJR A;  5EYT A;  4C5R A;  1W27 A;  1AUW A;  1VDK A;  5HW2 A;  2J91 A;  2O78 A;  3KDZ A;  1TJV A;  1HY1 A;  1T6P A;  1U15 A;  2X75 A;  2FUS A;  3QBP A;  1J3U A;  1B8F A;  4FLC A;  4V2Q A;  4EFC A;  1Y2M A;  1GK3 A;  2HVG A;  5EYV A;  1HY0 A;  1Q5N A; 
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