2RJSA

Sgtam bound to substrate mimic
Total Genus 198
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
198
sequence length
526
structure length
525
Chain Sequence
b'PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Tyrosine aminomutase
publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Isomerase
total genus 198
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjsA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjsA02
3OCFA 2QGAB 1Y2MA 1DCNA 4HGVA 4APAA 3KDYA 4C6GA 2RJSA 1HY1A 1FUQA 4BABA 3RD8A 2E9FA 2PTSA 4MX2A 3NZ4A 1C3CA 1GKJA 1KQ7A 4ADMA 1T6JA 1J3UA 5EYVA 4NLEA 3OCEA 1XWOA 3BHGA 4APBA 2YIIA 1TJVA 3GTDA 1GKMA 1GK3A 4C5UA 1K62A 2O7EA 4BAAA 4V2RA 2NYNA 1AUWA 4EEIA 3UNVA 3KDZA 1HY0A 2O7DA 1K7WA 1TJWA 1W27A 1YFMA 1Q5NA 5EYTA 1T6PA 1TJUA 4FLCA 1FUOA 3RRPA 3R6QA 3R6VA 4EFCA 3QBPA 1FUPA 3TV2A 2J91A 2PFMA 4C5RA 1U16A 4V2QA 1B8FA 1VDKA 2O7FA 2O78A 1EB4A 4ADLA 2HVGA 1C3UA 2PTRA 4CQ5A 2VD6A 1TJ7A 1DOFA 2O6YA 3E04A 3CZOA 3GZHA 1YISA 2FUSA 3NO9A 4NSLA 5HW2A 2NYFA 1I0AA 2PTQA 3R6YA 2X75A 5D6BA 1FURA 2QVEA 1JSWA 1U15A 5F91A 2RJRA 1YFEA 2O7BA 5F92A 2OHYA 4FFXA 1GK2A 1RE5A 3C8TA 4C5SA
chains in the Genus database with same CATH superfamily
3OCFA 2QGAB 1Y2MA 1DCNA 4HGVA 4APAA 5M0JA 3KDYA 4C6GA 2RJSA 1HY1A 1FUQA 4BABA 2E9FA 3RD8A 2PTSA 4MX2A 3NZ4A 1C3CA 1GKJA 4WNLA 2FELA 3CRVA 1KQ7A 4ADMA 1T6JA 1J3UA 5EYVA 4NLEA 3OCEA 1XWOA 3BHGA 4APBA 2YIIA 1TJVA 3GTDA 1GKMA 1XMDA 1XMCA 4A15A 1GK3A 4C5UA 1K62A 2O7EA 4BAAA 4V2RA 2NYNA 3CRW1 1AUWA 4EEIA 3UNVA 3KDZA 1HY0A 2O7DA 1K7WA 1TJWA 1W27A 1YFMA 1Q5NA 5H8WA 5EYTA 1T6PA 1TJUA 4FLCA 1FUOA 3RRPA 1XL7A 3R6QA 3R6VA 4EFCA 3QBPA 1FUPA 3TV2A 2J91A 2PFMA 4C5RA 1U16A 4V2QA 1B8FA 1VDKA 2O7FA 2O78A 2VSFA 1EB4A 4ADLA 2HVGA 1C3UA 2PTRA 4CQ5A 2VD6A 2VL7A 1TJ7A 1DOFA 2O6YA 3E04A 3CZOA 3GZHA 1XLYA 1YISA 2FENA 2FUSA 3NO9A 4NSLA 5HW2A 1XL8A 2NYFA 1I0AA 2PTQA 3R6YA 2X75A 5D6BA 1FURA 2QVEA 5M0IA 1JSWA 1U15A 5F91A 2RJRA 1YFEA 2O7BA 5F92A 2OHYA 4FFXA 1GK2A 1RE5A 3C8TA 4C5SA
chains in the Genus database with same CATH topology
3OCFA 2QGAB 1Y2MA 1DCNA 4HGVA 4APAA 3KDYA 4C6GA 2RJSA 1HY1A 1FUQA 4BABA 3RD8A 2E9FA 2PTSA 4MX2A 3NZ4A 1C3CA 1GKJA 1KQ7A 4ADMA 1T6JA 1J3UA 5EYVA 4NLEA 3OCEA 1XWOA 3BHGA 4APBA 2YIIA 1TJVA 3GTDA 1GKMA 1GK3A 4C5UA 1K62A 2O7EA 4BAAA 4V2RA 2NYNA 1AUWA 4EEIA 3UNVA 3KDZA 1HY0A 2O7DA 1K7WA 1TJWA 1W27A 1YFMA 1Q5NA 5EYTA 1T6PA 1TJUA 4FLCA 1FUOA 3RRPA 3R6QA 3R6VA 4EFCA 3QBPA 1FUPA 3TV2A 2J91A 2PFMA 4C5RA 1U16A 4V2QA 1B8FA 1VDKA 2O7FA 2O78A 1EB4A 4ADLA 2HVGA 1C3UA 2PTRA 4CQ5A 2VD6A 1TJ7A 1DOFA 2O6YA 3E04A 3CZOA 3GZHA 1YISA 2FUSA 3NO9A 4NSLA 5HW2A 2NYFA 1I0AA 2PTQA 3R6YA 2X75A 5D6BA 1FURA 2QVEA 1JSWA 1U15A 5F91A 2RJRA 1YFEA 2O7BA 5F92A 2OHYA 4FFXA 1GK2A 1RE5A 3C8TA 4C5SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OCF A;  2QGA B;  1Y2M A;  1DCN A;  4HGV A;  4APA A;  3KDY A;  4C6G A;  2RJS A;  1HY1 A;  1FUQ A;  4BAB A;  3RD8 A;  2E9F A;  2PTS A;  4MX2 A;  3NZ4 A;  1C3C A;  1GKJ A;  1KQ7 A;  4ADM A;  1T6J A;  1J3U A;  5EYV A;  4NLE A;  3OCE A;  1XWO A;  3BHG A;  4APB A;  2YII A;  1TJV A;  3GTD A;  1GKM A;  1GK3 A;  4C5U A;  1K62 A;  2O7E A;  4BAA A;  4V2R A;  2NYN A;  1AUW A;  4EEI A;  3UNV A;  3KDZ A;  1HY0 A;  2O7D A;  1K7W A;  1TJW A;  1W27 A;  1YFM A;  1Q5N A;  5EYT A;  1T6P A;  1TJU A;  4FLC A;  1FUO A;  3RRP A;  3R6Q A;  3R6V A;  4EFC A;  3QBP A;  1FUP A;  3TV2 A;  2J91 A;  2PFM A;  4C5R A;  1U16 A;  4V2Q A;  1B8F A;  1VDK A;  2O7F A;  2O78 A;  1EB4 A;  4ADL A;  2HVG A;  1C3U A;  2PTR A;  4CQ5 A;  2VD6 A;  1TJ7 A;  1DOF A;  2O6Y A;  3E04 A;  3CZO A;  3GZH A;  1YIS A;  2FUS A;  3NO9 A;  4NSL A;  5HW2 A;  2NYF A;  1I0A A;  2PTQ A;  3R6Y A;  2X75 A;  5D6B A;  1FUR A;  2QVE A;  1JSW A;  1U15 A;  5F91 A;  2RJR A;  1YFE A;  2O7B A;  5F92 A;  2OHY A;  4FFX A;  1GK2 A;  1RE5 A;  3C8T A;  4C5S A; 
#chains in the Genus database with same CATH topology
 3OCF A;  2QGA B;  1Y2M A;  1DCN A;  4HGV A;  4APA A;  5M0J A;  3KDY A;  4C6G A;  2RJS A;  1HY1 A;  1FUQ A;  4BAB A;  2E9F A;  3RD8 A;  2PTS A;  4MX2 A;  3NZ4 A;  1C3C A;  1GKJ A;  4WNL A;  2FEL A;  3CRV A;  1KQ7 A;  4ADM A;  1T6J A;  1J3U A;  5EYV A;  4NLE A;  3OCE A;  1XWO A;  3BHG A;  4APB A;  2YII A;  1TJV A;  3GTD A;  1GKM A;  1XMD A;  1XMC A;  4A15 A;  1GK3 A;  4C5U A;  1K62 A;  2O7E A;  4BAA A;  4V2R A;  2NYN A;  3CRW 1;  1AUW A;  4EEI A;  3UNV A;  3KDZ A;  1HY0 A;  2O7D A;  1K7W A;  1TJW A;  1W27 A;  1YFM A;  1Q5N A;  5H8W A;  5EYT A;  1T6P A;  1TJU A;  4FLC A;  1FUO A;  3RRP A;  1XL7 A;  3R6Q A;  3R6V A;  4EFC A;  3QBP A;  1FUP A;  3TV2 A;  2J91 A;  2PFM A;  4C5R A;  1U16 A;  4V2Q A;  1B8F A;  1VDK A;  2O7F A;  2O78 A;  2VSF A;  1EB4 A;  4ADL A;  2HVG A;  1C3U A;  2PTR A;  4CQ5 A;  2VD6 A;  2VL7 A;  1TJ7 A;  1DOF A;  2O6Y A;  3E04 A;  3CZO A;  3GZH A;  1XLY A;  1YIS A;  2FEN A;  2FUS A;  3NO9 A;  4NSL A;  5HW2 A;  1XL8 A;  2NYF A;  1I0A A;  2PTQ A;  3R6Y A;  2X75 A;  5D6B A;  1FUR A;  2QVE A;  5M0I A;  1JSW A;  1U15 A;  5F91 A;  2RJR A;  1YFE A;  2O7B A;  5F92 A;  2OHY A;  4FFX A;  1GK2 A;  1RE5 A;  3C8T A;  4C5S A; 
#chains in the Genus database with same CATH homology
 3OCF A;  2QGA B;  1Y2M A;  1DCN A;  4HGV A;  4APA A;  3KDY A;  4C6G A;  2RJS A;  1HY1 A;  1FUQ A;  4BAB A;  3RD8 A;  2E9F A;  2PTS A;  4MX2 A;  3NZ4 A;  1C3C A;  1GKJ A;  1KQ7 A;  4ADM A;  1T6J A;  1J3U A;  5EYV A;  4NLE A;  3OCE A;  1XWO A;  3BHG A;  4APB A;  2YII A;  1TJV A;  3GTD A;  1GKM A;  1GK3 A;  4C5U A;  1K62 A;  2O7E A;  4BAA A;  4V2R A;  2NYN A;  1AUW A;  4EEI A;  3UNV A;  3KDZ A;  1HY0 A;  2O7D A;  1K7W A;  1TJW A;  1W27 A;  1YFM A;  1Q5N A;  5EYT A;  1T6P A;  1TJU A;  4FLC A;  1FUO A;  3RRP A;  3R6Q A;  3R6V A;  4EFC A;  3QBP A;  1FUP A;  3TV2 A;  2J91 A;  2PFM A;  4C5R A;  1U16 A;  4V2Q A;  1B8F A;  1VDK A;  2O7F A;  2O78 A;  1EB4 A;  4ADL A;  2HVG A;  1C3U A;  2PTR A;  4CQ5 A;  2VD6 A;  1TJ7 A;  1DOF A;  2O6Y A;  3E04 A;  3CZO A;  3GZH A;  1YIS A;  2FUS A;  3NO9 A;  4NSL A;  5HW2 A;  2NYF A;  1I0A A;  2PTQ A;  3R6Y A;  2X75 A;  5D6B A;  1FUR A;  2QVE A;  1JSW A;  1U15 A;  5F91 A;  2RJR A;  1YFE A;  2O7B A;  5F92 A;  2OHY A;  4FFX A;  1GK2 A;  1RE5 A;  3C8T A;  4C5S A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...