2RJSA

Sgtam bound to substrate mimic
Total Genus 198
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
198
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM.
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Isomerase
molecule keywords Tyrosine aminomutase
total genus 198
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2rjsA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2rjsA02
5EYVA 1C3CA 4FFXA 4HGVA 3CZOA 4ADMA 3E04A 1TJUA 2HVGA 1DOFA 1FURA 3R6YA 1EB4A 1TJ7A 1K7WA 1FUPA 2FUSA 1T6JA 4C5RA 2PFMA 3R6QA 3NZ4A 4NSLA 1GK3A 1U15A 2RJRA 3OCFA 5F91A 4FLCA 1VDKA 1K62A 1HY0A 2VD6A 3C8TA 3OCEA 1YFEA 2OHYA 3NO9A 1FUOA 4V2QA 3GTDA 3GZHA 4BABA 1DCNA 1RE5A 4APBA 2E9FA 1J3UA 1B8FA 2NYFA 1FUQA 5HW2A 4V2RA 3KDZA 4ADLA 3BHGA 2X75A 1C3UA 4C5SA 4CQ5A 5D6BA 2O6YA 1XWOA 4EFCA 3RD8A 2O78A 4MX2A 1I0AA 5F92A 3R6VA 1GKMA 1Q5NA 2O7BA 1U16A 4APAA 1W27A 4C6GA 2O7FA 3TV2A 3QBPA 1TJVA 1JSWA 2QGAB 1KQ7A 4EEIA 1Y2MA 2PTSA 5EYTA 2RJSA 2O7DA 1TJWA 4BAAA 1GK2A 2PTQA 1YISA 2PTRA 3RRPA 2NYNA 2QVEA 3UNVA 1AUWA 2YIIA 2O7EA 1GKJA 1YFMA 1HY1A 2J91A 1T6PA 4C5UA 4NLEA 3KDYA
chains in the Genus database with same CATH superfamily
5EYVA 1C3CA 4FFXA 4HGVA 3CZOA 4ADMA 3E04A 5M0IA 1TJUA 2HVGA 1DOFA 1XMCA 1FURA 3R6YA 1EB4A 1TJ7A 1K7WA 1FUPA 2FUSA 5H8WA 1T6JA 4C5RA 2PFMA 3R6QA 3NZ4A 1XMDA 1GK3A 4NSLA 1U15A 2RJRA 3OCFA 5F91A 4FLCA 1VDKA 1K62A 1HY0A 2VD6A 3C8TA 3OCEA 1YFEA 2OHYA 3NO9A 1XL8A 2FELA 1FUOA 4V2QA 3CRVA 3GTDA 3GZHA 4BABA 1DCNA 1RE5A 4APBA 2E9FA 1J3UA 1B8FA 2NYFA 1XLYA 1FUQA 5HW2A 4V2RA 3KDZA 4ADLA 3BHGA 2X75A 1C3UA 4C5SA 4CQ5A 5D6BA 2O6YA 1XWOA 5M0JA 4EFCA 3RD8A 2FENA 2O78A 4MX2A 1I0AA 5F92A 3R6VA 1GKMA 1Q5NA 4WNLA 4A15A 2O7BA 1U16A 4APAA 1W27A 4C6GA 2O7FA 3TV2A 3QBPA 1TJVA 1JSWA 2QGAB 1KQ7A 1XL7A 4EEIA 1Y2MA 2VL7A 2PTSA 5EYTA 2RJSA 2VSFA 2O7DA 1TJWA 4BAAA 3CRW1 1GK2A 2PTQA 1YISA 2PTRA 3RRPA 2NYNA 2QVEA 3UNVA 1AUWA 2YIIA 2O7EA 1GKJA 1YFMA 1HY1A 2J91A 1T6PA 4C5UA 4NLEA 3KDYA
chains in the Genus database with same CATH topology
5EYVA 1C3CA 4FFXA 4HGVA 3CZOA 4ADMA 3E04A 1TJUA 2HVGA 1DOFA 1FURA 3R6YA 1EB4A 1TJ7A 1K7WA 1FUPA 2FUSA 1T6JA 4C5RA 2PFMA 3R6QA 3NZ4A 4NSLA 1GK3A 1U15A 2RJRA 3OCFA 5F91A 4FLCA 1VDKA 1K62A 1HY0A 2VD6A 3C8TA 3OCEA 1YFEA 2OHYA 3NO9A 1FUOA 4V2QA 3GTDA 3GZHA 4BABA 1DCNA 1RE5A 4APBA 2E9FA 1J3UA 1B8FA 2NYFA 1FUQA 5HW2A 4V2RA 3KDZA 4ADLA 3BHGA 2X75A 1C3UA 4C5SA 4CQ5A 5D6BA 2O6YA 1XWOA 4EFCA 3RD8A 2O78A 4MX2A 1I0AA 5F92A 3R6VA 1GKMA 1Q5NA 2O7BA 1U16A 4APAA 1W27A 4C6GA 2O7FA 3TV2A 3QBPA 1TJVA 1JSWA 2QGAB 1KQ7A 4EEIA 1Y2MA 2PTSA 5EYTA 2RJSA 2O7DA 1TJWA 4BAAA 1GK2A 2PTQA 1YISA 2PTRA 3RRPA 2NYNA 2QVEA 3UNVA 1AUWA 2YIIA 2O7EA 1GKJA 1YFMA 1HY1A 2J91A 1T6PA 4C5UA 4NLEA 3KDYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EYV A;  1C3C A;  4FFX A;  4HGV A;  3CZO A;  4ADM A;  3E04 A;  1TJU A;  2HVG A;  1DOF A;  1FUR A;  3R6Y A;  1EB4 A;  1TJ7 A;  1K7W A;  1FUP A;  2FUS A;  1T6J A;  4C5R A;  2PFM A;  3R6Q A;  3NZ4 A;  4NSL A;  1GK3 A;  1U15 A;  2RJR A;  3OCF A;  5F91 A;  4FLC A;  1VDK A;  1K62 A;  1HY0 A;  2VD6 A;  3C8T A;  3OCE A;  1YFE A;  2OHY A;  3NO9 A;  1FUO A;  4V2Q A;  3GTD A;  3GZH A;  4BAB A;  1DCN A;  1RE5 A;  4APB A;  2E9F A;  1J3U A;  1B8F A;  2NYF A;  1FUQ A;  5HW2 A;  4V2R A;  3KDZ A;  4ADL A;  3BHG A;  2X75 A;  1C3U A;  4C5S A;  4CQ5 A;  5D6B A;  2O6Y A;  1XWO A;  4EFC A;  3RD8 A;  2O78 A;  4MX2 A;  1I0A A;  5F92 A;  3R6V A;  1GKM A;  1Q5N A;  2O7B A;  1U16 A;  4APA A;  1W27 A;  4C6G A;  2O7F A;  3TV2 A;  3QBP A;  1TJV A;  1JSW A;  2QGA B;  1KQ7 A;  4EEI A;  1Y2M A;  2PTS A;  5EYT A;  2RJS A;  2O7D A;  1TJW A;  4BAA A;  1GK2 A;  2PTQ A;  1YIS A;  2PTR A;  3RRP A;  2NYN A;  2QVE A;  3UNV A;  1AUW A;  2YII A;  2O7E A;  1GKJ A;  1YFM A;  1HY1 A;  2J91 A;  1T6P A;  4C5U A;  4NLE A;  3KDY A; 
#chains in the Genus database with same CATH topology
 5EYV A;  1C3C A;  4FFX A;  4HGV A;  3CZO A;  4ADM A;  3E04 A;  5M0I A;  1TJU A;  2HVG A;  1DOF A;  1XMC A;  1FUR A;  3R6Y A;  1EB4 A;  1TJ7 A;  1K7W A;  1FUP A;  2FUS A;  5H8W A;  1T6J A;  4C5R A;  2PFM A;  3R6Q A;  3NZ4 A;  1XMD A;  1GK3 A;  4NSL A;  1U15 A;  2RJR A;  3OCF A;  5F91 A;  4FLC A;  1VDK A;  1K62 A;  1HY0 A;  2VD6 A;  3C8T A;  3OCE A;  1YFE A;  2OHY A;  3NO9 A;  1XL8 A;  2FEL A;  1FUO A;  4V2Q A;  3CRV A;  3GTD A;  3GZH A;  4BAB A;  1DCN A;  1RE5 A;  4APB A;  2E9F A;  1J3U A;  1B8F A;  2NYF A;  1XLY A;  1FUQ A;  5HW2 A;  4V2R A;  3KDZ A;  4ADL A;  3BHG A;  2X75 A;  1C3U A;  4C5S A;  4CQ5 A;  5D6B A;  2O6Y A;  1XWO A;  5M0J A;  4EFC A;  3RD8 A;  2FEN A;  2O78 A;  4MX2 A;  1I0A A;  5F92 A;  3R6V A;  1GKM A;  1Q5N A;  4WNL A;  4A15 A;  2O7B A;  1U16 A;  4APA A;  1W27 A;  4C6G A;  2O7F A;  3TV2 A;  3QBP A;  1TJV A;  1JSW A;  2QGA B;  1KQ7 A;  1XL7 A;  4EEI A;  1Y2M A;  2VL7 A;  2PTS A;  5EYT A;  2RJS A;  2VSF A;  2O7D A;  1TJW A;  4BAA A;  3CRW 1;  1GK2 A;  2PTQ A;  1YIS A;  2PTR A;  3RRP A;  2NYN A;  2QVE A;  3UNV A;  1AUW A;  2YII A;  2O7E A;  1GKJ A;  1YFM A;  1HY1 A;  2J91 A;  1T6P A;  4C5U A;  4NLE A;  3KDY A; 
#chains in the Genus database with same CATH homology
 5EYV A;  1C3C A;  4FFX A;  4HGV A;  3CZO A;  4ADM A;  3E04 A;  1TJU A;  2HVG A;  1DOF A;  1FUR A;  3R6Y A;  1EB4 A;  1TJ7 A;  1K7W A;  1FUP A;  2FUS A;  1T6J A;  4C5R A;  2PFM A;  3R6Q A;  3NZ4 A;  4NSL A;  1GK3 A;  1U15 A;  2RJR A;  3OCF A;  5F91 A;  4FLC A;  1VDK A;  1K62 A;  1HY0 A;  2VD6 A;  3C8T A;  3OCE A;  1YFE A;  2OHY A;  3NO9 A;  1FUO A;  4V2Q A;  3GTD A;  3GZH A;  4BAB A;  1DCN A;  1RE5 A;  4APB A;  2E9F A;  1J3U A;  1B8F A;  2NYF A;  1FUQ A;  5HW2 A;  4V2R A;  3KDZ A;  4ADL A;  3BHG A;  2X75 A;  1C3U A;  4C5S A;  4CQ5 A;  5D6B A;  2O6Y A;  1XWO A;  4EFC A;  3RD8 A;  2O78 A;  4MX2 A;  1I0A A;  5F92 A;  3R6V A;  1GKM A;  1Q5N A;  2O7B A;  1U16 A;  4APA A;  1W27 A;  4C6G A;  2O7F A;  3TV2 A;  3QBP A;  1TJV A;  1JSW A;  2QGA B;  1KQ7 A;  4EEI A;  1Y2M A;  2PTS A;  5EYT A;  2RJS A;  2O7D A;  1TJW A;  4BAA A;  1GK2 A;  2PTQ A;  1YIS A;  2PTR A;  3RRP A;  2NYN A;  2QVE A;  3UNV A;  1AUW A;  2YII A;  2O7E A;  1GKJ A;  1YFM A;  1HY1 A;  2J91 A;  1T6P A;  4C5U A;  4NLE A;  3KDY A; 
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