2O7DA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with caffeate
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
total genus 193
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7dA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7dA02
2QGAB 2HVGA 1GK2A 1HY1A 4ADLA 3UNVA 4EEIA 1YISA 1TJUA 2E9FA 2YIIA 1U16A 2O7DA 5F91A 1XWOA 1JSWA 2PTQA 1U15A 3TV2A 2OHYA 3R6QA 1TJWA 1GK3A 1RE5A 2J91A 3BHGA 4NSLA 3KDZA 2VD6A 1C3UA 2FUSA 1C3CA 4C5SA 3QBPA 1FUPA 3OCEA 2O78A 4C5UA 2O7BA 3CZOA 1K7WA 5F92A 4C5RA 4NLEA 1EB4A 3E04A 5HW2A 2O6YA 1J3UA 2PTSA 1GKJA 1Q5NA 1VDKA 4CQ5A 1K62A 4C6GA 4HGVA 2X75A 1YFMA 4V2QA 4FFXA 1T6JA 1AUWA 1DOFA 2O7FA 1FUQA 1Y2MA 4APAA 1FURA 1KQ7A 4BAAA 1I0AA 1GKMA 3R6YA 3C8TA 3RRPA 1DCNA 4EFCA 3GZHA 1HY0A 2RJRA 3KDYA 1TJ7A 3R6VA 4ADMA 4BABA 4APBA 5EYTA 5D6BA 4FLCA 4V2RA 2RJSA 4MX2A 1W27A 3GTDA 1B8FA 2PFMA 3RD8A 2QVEA 2NYNA 2O7EA 1YFEA 1FUOA 5EYVA 2NYFA 1T6PA 1TJVA 3NO9A 3NZ4A 2PTRA 3OCFA
chains in the Genus database with same CATH superfamily
2QGAB 2HVGA 5M0IA 1GK2A 4WNLA 1HY1A 4ADLA 3UNVA 4EEIA 1YISA 1TJUA 2E9FA 2YIIA 1U16A 2O7DA 5F91A 1XLYA 1XWOA 1JSWA 2PTQA 1U15A 3TV2A 2OHYA 3R6QA 1TJWA 1XMCA 2VSFA 1GK3A 1RE5A 2J91A 3BHGA 4NSLA 3KDZA 2VD6A 5H8WA 1C3UA 2FUSA 1C3CA 4C5SA 3QBPA 1FUPA 3OCEA 2O78A 4C5UA 2O7BA 3CZOA 1K7WA 5F92A 4C5RA 4NLEA 2FELA 1EB4A 3E04A 5HW2A 2O6YA 1J3UA 2PTSA 1GKJA 1Q5NA 1VDKA 4CQ5A 1K62A 4C6GA 4HGVA 2X75A 1YFMA 4V2QA 4FFXA 1T6JA 1AUWA 1DOFA 2O7FA 1FUQA 1Y2MA 4APAA 1FURA 2VL7A 2FENA 1XMDA 4A15A 1KQ7A 4BAAA 1I0AA 1GKMA 3R6YA 3C8TA 3RRPA 1DCNA 1XL7A 4EFCA 3GZHA 1HY0A 2RJRA 3KDYA 1TJ7A 3R6VA 4ADMA 4BABA 4APBA 3CRVA 5EYTA 5D6BA 4FLCA 4V2RA 2RJSA 4MX2A 1W27A 3GTDA 1B8FA 2PFMA 3RD8A 2QVEA 2NYNA 2O7EA 1YFEA 1FUOA 5EYVA 2NYFA 3CRW1 1T6PA 5M0JA 1TJVA 3NO9A 3NZ4A 1XL8A 2PTRA 3OCFA
chains in the Genus database with same CATH topology
2QGAB 2HVGA 1GK2A 1HY1A 4ADLA 3UNVA 4EEIA 1YISA 1TJUA 2E9FA 2YIIA 1U16A 2O7DA 5F91A 1XWOA 1JSWA 2PTQA 1U15A 3TV2A 2OHYA 3R6QA 1TJWA 1GK3A 1RE5A 2J91A 3BHGA 4NSLA 3KDZA 2VD6A 1C3UA 2FUSA 1C3CA 4C5SA 3QBPA 1FUPA 3OCEA 2O78A 4C5UA 2O7BA 3CZOA 1K7WA 5F92A 4C5RA 4NLEA 1EB4A 3E04A 5HW2A 2O6YA 1J3UA 2PTSA 1GKJA 1Q5NA 1VDKA 4CQ5A 1K62A 4C6GA 4HGVA 2X75A 1YFMA 4V2QA 4FFXA 1T6JA 1AUWA 1DOFA 2O7FA 1FUQA 1Y2MA 4APAA 1FURA 1KQ7A 4BAAA 1I0AA 1GKMA 3R6YA 3C8TA 3RRPA 1DCNA 4EFCA 3GZHA 1HY0A 2RJRA 3KDYA 1TJ7A 3R6VA 4ADMA 4BABA 4APBA 5EYTA 5D6BA 4FLCA 4V2RA 2RJSA 4MX2A 1W27A 3GTDA 1B8FA 2PFMA 3RD8A 2QVEA 2NYNA 2O7EA 1YFEA 1FUOA 5EYVA 2NYFA 1T6PA 1TJVA 3NO9A 3NZ4A 2PTRA 3OCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QGA B;  2HVG A;  1GK2 A;  1HY1 A;  4ADL A;  3UNV A;  4EEI A;  1YIS A;  1TJU A;  2E9F A;  2YII A;  1U16 A;  2O7D A;  5F91 A;  1XWO A;  1JSW A;  2PTQ A;  1U15 A;  3TV2 A;  2OHY A;  3R6Q A;  1TJW A;  1GK3 A;  1RE5 A;  2J91 A;  3BHG A;  4NSL A;  3KDZ A;  2VD6 A;  1C3U A;  2FUS A;  1C3C A;  4C5S A;  3QBP A;  1FUP A;  3OCE A;  2O78 A;  4C5U A;  2O7B A;  3CZO A;  1K7W A;  5F92 A;  4C5R A;  4NLE A;  1EB4 A;  3E04 A;  5HW2 A;  2O6Y A;  1J3U A;  2PTS A;  1GKJ A;  1Q5N A;  1VDK A;  4CQ5 A;  1K62 A;  4C6G A;  4HGV A;  2X75 A;  1YFM A;  4V2Q A;  4FFX A;  1T6J A;  1AUW A;  1DOF A;  2O7F A;  1FUQ A;  1Y2M A;  4APA A;  1FUR A;  1KQ7 A;  4BAA A;  1I0A A;  1GKM A;  3R6Y A;  3C8T A;  3RRP A;  1DCN A;  4EFC A;  3GZH A;  1HY0 A;  2RJR A;  3KDY A;  1TJ7 A;  3R6V A;  4ADM A;  4BAB A;  4APB A;  5EYT A;  5D6B A;  4FLC A;  4V2R A;  2RJS A;  4MX2 A;  1W27 A;  3GTD A;  1B8F A;  2PFM A;  3RD8 A;  2QVE A;  2NYN A;  2O7E A;  1YFE A;  1FUO A;  5EYV A;  2NYF A;  1T6P A;  1TJV A;  3NO9 A;  3NZ4 A;  2PTR A;  3OCF A; 
#chains in the Genus database with same CATH topology
 2QGA B;  2HVG A;  5M0I A;  1GK2 A;  4WNL A;  1HY1 A;  4ADL A;  3UNV A;  4EEI A;  1YIS A;  1TJU A;  2E9F A;  2YII A;  1U16 A;  2O7D A;  5F91 A;  1XLY A;  1XWO A;  1JSW A;  2PTQ A;  1U15 A;  3TV2 A;  2OHY A;  3R6Q A;  1TJW A;  1XMC A;  2VSF A;  1GK3 A;  1RE5 A;  2J91 A;  3BHG A;  4NSL A;  3KDZ A;  2VD6 A;  5H8W A;  1C3U A;  2FUS A;  1C3C A;  4C5S A;  3QBP A;  1FUP A;  3OCE A;  2O78 A;  4C5U A;  2O7B A;  3CZO A;  1K7W A;  5F92 A;  4C5R A;  4NLE A;  2FEL A;  1EB4 A;  3E04 A;  5HW2 A;  2O6Y A;  1J3U A;  2PTS A;  1GKJ A;  1Q5N A;  1VDK A;  4CQ5 A;  1K62 A;  4C6G A;  4HGV A;  2X75 A;  1YFM A;  4V2Q A;  4FFX A;  1T6J A;  1AUW A;  1DOF A;  2O7F A;  1FUQ A;  1Y2M A;  4APA A;  1FUR A;  2VL7 A;  2FEN A;  1XMD A;  4A15 A;  1KQ7 A;  4BAA A;  1I0A A;  1GKM A;  3R6Y A;  3C8T A;  3RRP A;  1DCN A;  1XL7 A;  4EFC A;  3GZH A;  1HY0 A;  2RJR A;  3KDY A;  1TJ7 A;  3R6V A;  4ADM A;  4BAB A;  4APB A;  3CRV A;  5EYT A;  5D6B A;  4FLC A;  4V2R A;  2RJS A;  4MX2 A;  1W27 A;  3GTD A;  1B8F A;  2PFM A;  3RD8 A;  2QVE A;  2NYN A;  2O7E A;  1YFE A;  1FUO A;  5EYV A;  2NYF A;  3CRW 1;  1T6P A;  5M0J A;  1TJV A;  3NO9 A;  3NZ4 A;  1XL8 A;  2PTR A;  3OCF A; 
#chains in the Genus database with same CATH homology
 2QGA B;  2HVG A;  1GK2 A;  1HY1 A;  4ADL A;  3UNV A;  4EEI A;  1YIS A;  1TJU A;  2E9F A;  2YII A;  1U16 A;  2O7D A;  5F91 A;  1XWO A;  1JSW A;  2PTQ A;  1U15 A;  3TV2 A;  2OHY A;  3R6Q A;  1TJW A;  1GK3 A;  1RE5 A;  2J91 A;  3BHG A;  4NSL A;  3KDZ A;  2VD6 A;  1C3U A;  2FUS A;  1C3C A;  4C5S A;  3QBP A;  1FUP A;  3OCE A;  2O78 A;  4C5U A;  2O7B A;  3CZO A;  1K7W A;  5F92 A;  4C5R A;  4NLE A;  1EB4 A;  3E04 A;  5HW2 A;  2O6Y A;  1J3U A;  2PTS A;  1GKJ A;  1Q5N A;  1VDK A;  4CQ5 A;  1K62 A;  4C6G A;  4HGV A;  2X75 A;  1YFM A;  4V2Q A;  4FFX A;  1T6J A;  1AUW A;  1DOF A;  2O7F A;  1FUQ A;  1Y2M A;  4APA A;  1FUR A;  1KQ7 A;  4BAA A;  1I0A A;  1GKM A;  3R6Y A;  3C8T A;  3RRP A;  1DCN A;  4EFC A;  3GZH A;  1HY0 A;  2RJR A;  3KDY A;  1TJ7 A;  3R6V A;  4ADM A;  4BAB A;  4APB A;  5EYT A;  5D6B A;  4FLC A;  4V2R A;  2RJS A;  4MX2 A;  1W27 A;  3GTD A;  1B8F A;  2PFM A;  3RD8 A;  2QVE A;  2NYN A;  2O7E A;  1YFE A;  1FUO A;  5EYV A;  2NYF A;  1T6P A;  1TJV A;  3NO9 A;  3NZ4 A;  2PTR A;  3OCF A; 
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