2O7DA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with caffeate
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
molecule keywords Putative histidine ammonia-lyase
molecule tags Lyase
source organism Rhodobacter sphaeroides
total genus 193
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7dA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7dA02
1DOFA 2OHYA 1DCNA 3UNVA 3E04A 1J3UA 2RJSA 4APAA 1C3UA 2PTRA 3R6YA 4ADLA 1XWOA 1TJWA 3RRPA 1FURA 3NO9A 4C6GA 3KDYA 1YISA 1FUOA 4APBA 2HVGA 3GTDA 1TJUA 1JSWA 1W27A 2YIIA 1HY0A 4FFXA 3R6VA 1Y2MA 4V2RA 4MX2A 1T6PA 1GKJA 1VDKA 4NSLA 3NZ4A 2FUSA 4NLEA 4C5RA 4HGVA 2NYNA 1FUPA 4V2QA 3OCEA 1YFEA 3OCFA 1YFMA 5F92A 2O6YA 1HY1A 5EYVA 2PFMA 1FUQA 2X75A 1RE5A 2PTQA 3CZOA 3KDZA 2RJRA 2QVEA 1T6JA 3R6QA 2NYFA 4EFCA 1K62A 3GZHA 5EYTA 2O78A 2J91A 1GK2A 4CQ5A 1Q5NA 2O7DA 2E9FA 1KQ7A 5F91A 3C8TA 1U16A 4C5SA 2QGAB 1I0AA 4BABA 1B8FA 1GKMA 1TJ7A 3BHGA 4BAAA 4FLCA 1C3CA 1K7WA 2O7EA 2VD6A 2O7BA 1GK3A 1TJVA 3QBPA 3RD8A 4ADMA 1AUWA 4EEIA 5D6BA 3TV2A 2O7FA 5HW2A 2PTSA 1EB4A 4C5UA 1U15A
chains in the Genus database with same CATH superfamily
1DOFA 2OHYA 1DCNA 3UNVA 3E04A 1J3UA 2RJSA 4APAA 1C3UA 2PTRA 2VSFA 3R6YA 4ADLA 1XWOA 1TJWA 3RRPA 1XLYA 1FURA 3NO9A 5H8WA 4C6GA 3KDYA 1YISA 1FUOA 1XL7A 4APBA 2HVGA 3GTDA 1XL8A 1TJUA 1JSWA 3CRW1 1W27A 2YIIA 1HY0A 4FFXA 5M0JA 3R6VA 1Y2MA 4V2RA 4MX2A 1T6PA 1GKJA 1VDKA 4NSLA 2FELA 3NZ4A 2FUSA 4NLEA 4C5RA 4HGVA 2NYNA 1FUPA 4V2QA 3OCEA 1YFEA 3OCFA 1YFMA 5F92A 2O6YA 1HY1A 5EYVA 2PFMA 4WNLA 1FUQA 2X75A 1RE5A 2PTQA 3CZOA 3KDZA 2RJRA 2VL7A 2QVEA 1T6JA 3R6QA 5M0IA 2NYFA 4EFCA 1K62A 3GZHA 5EYTA 2O78A 2J91A 1GK2A 4CQ5A 1Q5NA 2O7DA 2E9FA 4A15A 1KQ7A 5F91A 3C8TA 1U16A 4C5SA 2QGAB 1I0AA 4BABA 1B8FA 1GKMA 1TJ7A 3BHGA 2FENA 4BAAA 4FLCA 1C3CA 1K7WA 2O7EA 2VD6A 1XMCA 2O7BA 1GK3A 1TJVA 3QBPA 3RD8A 4ADMA 1AUWA 4EEIA 5D6BA 1XMDA 3TV2A 2O7FA 3CRVA 5HW2A 2PTSA 1EB4A 4C5UA 1U15A
chains in the Genus database with same CATH topology
1DOFA 2OHYA 1DCNA 3UNVA 3E04A 1J3UA 2RJSA 4APAA 1C3UA 2PTRA 3R6YA 4ADLA 1XWOA 1TJWA 3RRPA 1FURA 3NO9A 4C6GA 3KDYA 1YISA 1FUOA 4APBA 2HVGA 3GTDA 1TJUA 1JSWA 1W27A 2YIIA 1HY0A 4FFXA 3R6VA 1Y2MA 4V2RA 4MX2A 1T6PA 1GKJA 1VDKA 4NSLA 3NZ4A 2FUSA 4NLEA 4C5RA 4HGVA 2NYNA 1FUPA 4V2QA 3OCEA 1YFEA 3OCFA 1YFMA 5F92A 2O6YA 1HY1A 5EYVA 2PFMA 1FUQA 2X75A 1RE5A 2PTQA 3CZOA 3KDZA 2RJRA 2QVEA 1T6JA 3R6QA 2NYFA 4EFCA 1K62A 3GZHA 5EYTA 2O78A 2J91A 1GK2A 4CQ5A 1Q5NA 2O7DA 2E9FA 1KQ7A 5F91A 3C8TA 1U16A 4C5SA 2QGAB 1I0AA 4BABA 1B8FA 1GKMA 1TJ7A 3BHGA 4BAAA 4FLCA 1C3CA 1K7WA 2O7EA 2VD6A 2O7BA 1GK3A 1TJVA 3QBPA 3RD8A 4ADMA 1AUWA 4EEIA 5D6BA 3TV2A 2O7FA 5HW2A 2PTSA 1EB4A 4C5UA 1U15A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DOF A;  2OHY A;  1DCN A;  3UNV A;  3E04 A;  1J3U A;  2RJS A;  4APA A;  1C3U A;  2PTR A;  3R6Y A;  4ADL A;  1XWO A;  1TJW A;  3RRP A;  1FUR A;  3NO9 A;  4C6G A;  3KDY A;  1YIS A;  1FUO A;  4APB A;  2HVG A;  3GTD A;  1TJU A;  1JSW A;  1W27 A;  2YII A;  1HY0 A;  4FFX A;  3R6V A;  1Y2M A;  4V2R A;  4MX2 A;  1T6P A;  1GKJ A;  1VDK A;  4NSL A;  3NZ4 A;  2FUS A;  4NLE A;  4C5R A;  4HGV A;  2NYN A;  1FUP A;  4V2Q A;  3OCE A;  1YFE A;  3OCF A;  1YFM A;  5F92 A;  2O6Y A;  1HY1 A;  5EYV A;  2PFM A;  1FUQ A;  2X75 A;  1RE5 A;  2PTQ A;  3CZO A;  3KDZ A;  2RJR A;  2QVE A;  1T6J A;  3R6Q A;  2NYF A;  4EFC A;  1K62 A;  3GZH A;  5EYT A;  2O78 A;  2J91 A;  1GK2 A;  4CQ5 A;  1Q5N A;  2O7D A;  2E9F A;  1KQ7 A;  5F91 A;  3C8T A;  1U16 A;  4C5S A;  2QGA B;  1I0A A;  4BAB A;  1B8F A;  1GKM A;  1TJ7 A;  3BHG A;  4BAA A;  4FLC A;  1C3C A;  1K7W A;  2O7E A;  2VD6 A;  2O7B A;  1GK3 A;  1TJV A;  3QBP A;  3RD8 A;  4ADM A;  1AUW A;  4EEI A;  5D6B A;  3TV2 A;  2O7F A;  5HW2 A;  2PTS A;  1EB4 A;  4C5U A;  1U15 A; 
#chains in the Genus database with same CATH topology
 1DOF A;  2OHY A;  1DCN A;  3UNV A;  3E04 A;  1J3U A;  2RJS A;  4APA A;  1C3U A;  2PTR A;  2VSF A;  3R6Y A;  4ADL A;  1XWO A;  1TJW A;  3RRP A;  1XLY A;  1FUR A;  3NO9 A;  5H8W A;  4C6G A;  3KDY A;  1YIS A;  1FUO A;  1XL7 A;  4APB A;  2HVG A;  3GTD A;  1XL8 A;  1TJU A;  1JSW A;  3CRW 1;  1W27 A;  2YII A;  1HY0 A;  4FFX A;  5M0J A;  3R6V A;  1Y2M A;  4V2R A;  4MX2 A;  1T6P A;  1GKJ A;  1VDK A;  4NSL A;  2FEL A;  3NZ4 A;  2FUS A;  4NLE A;  4C5R A;  4HGV A;  2NYN A;  1FUP A;  4V2Q A;  3OCE A;  1YFE A;  3OCF A;  1YFM A;  5F92 A;  2O6Y A;  1HY1 A;  5EYV A;  2PFM A;  4WNL A;  1FUQ A;  2X75 A;  1RE5 A;  2PTQ A;  3CZO A;  3KDZ A;  2RJR A;  2VL7 A;  2QVE A;  1T6J A;  3R6Q A;  5M0I A;  2NYF A;  4EFC A;  1K62 A;  3GZH A;  5EYT A;  2O78 A;  2J91 A;  1GK2 A;  4CQ5 A;  1Q5N A;  2O7D A;  2E9F A;  4A15 A;  1KQ7 A;  5F91 A;  3C8T A;  1U16 A;  4C5S A;  2QGA B;  1I0A A;  4BAB A;  1B8F A;  1GKM A;  1TJ7 A;  3BHG A;  2FEN A;  4BAA A;  4FLC A;  1C3C A;  1K7W A;  2O7E A;  2VD6 A;  1XMC A;  2O7B A;  1GK3 A;  1TJV A;  3QBP A;  3RD8 A;  4ADM A;  1AUW A;  4EEI A;  5D6B A;  1XMD A;  3TV2 A;  2O7F A;  3CRV A;  5HW2 A;  2PTS A;  1EB4 A;  4C5U A;  1U15 A; 
#chains in the Genus database with same CATH homology
 1DOF A;  2OHY A;  1DCN A;  3UNV A;  3E04 A;  1J3U A;  2RJS A;  4APA A;  1C3U A;  2PTR A;  3R6Y A;  4ADL A;  1XWO A;  1TJW A;  3RRP A;  1FUR A;  3NO9 A;  4C6G A;  3KDY A;  1YIS A;  1FUO A;  4APB A;  2HVG A;  3GTD A;  1TJU A;  1JSW A;  1W27 A;  2YII A;  1HY0 A;  4FFX A;  3R6V A;  1Y2M A;  4V2R A;  4MX2 A;  1T6P A;  1GKJ A;  1VDK A;  4NSL A;  3NZ4 A;  2FUS A;  4NLE A;  4C5R A;  4HGV A;  2NYN A;  1FUP A;  4V2Q A;  3OCE A;  1YFE A;  3OCF A;  1YFM A;  5F92 A;  2O6Y A;  1HY1 A;  5EYV A;  2PFM A;  1FUQ A;  2X75 A;  1RE5 A;  2PTQ A;  3CZO A;  3KDZ A;  2RJR A;  2QVE A;  1T6J A;  3R6Q A;  2NYF A;  4EFC A;  1K62 A;  3GZH A;  5EYT A;  2O78 A;  2J91 A;  1GK2 A;  4CQ5 A;  1Q5N A;  2O7D A;  2E9F A;  1KQ7 A;  5F91 A;  3C8T A;  1U16 A;  4C5S A;  2QGA B;  1I0A A;  4BAB A;  1B8F A;  1GKM A;  1TJ7 A;  3BHG A;  4BAA A;  4FLC A;  1C3C A;  1K7W A;  2O7E A;  2VD6 A;  2O7B A;  1GK3 A;  1TJV A;  3QBP A;  3RD8 A;  4ADM A;  1AUW A;  4EEI A;  5D6B A;  3TV2 A;  2O7F A;  5HW2 A;  2PTS A;  1EB4 A;  4C5U A;  1U15 A; 
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