2O7DA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with caffeate
Total Genus 193
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
total genus 193
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7dA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7dA02
3R6QA 4V2QA 4EEIA 2YIIA 1K7WA 2NYNA 4HGVA 1KQ7A 3NZ4A 1GKJA 1U15A 1T6JA 2O78A 5F91A 3RD8A 1TJUA 3KDZA 4APBA 2O7FA 1B8FA 4FLCA 1GK3A 1T6PA 2QGAB 5F92A 1C3CA 1J3UA 3RRPA 1DOFA 1I0AA 1DCNA 2O6YA 4ADLA 1FUPA 2X75A 2VD6A 1VDKA 1GKMA 5HW2A 2O7EA 2PTRA 1YISA 1TJ7A 1AUWA 3GTDA 3UNVA 3R6YA 4FFXA 2HVGA 2NYFA 1C3UA 4V2RA 3BHGA 2QVEA 3QBPA 1FURA 1XWOA 4ADMA 4C5RA 4C6GA 5D6BA 1Y2MA 2RJSA 2O7BA 4C5SA 4CQ5A 1YFMA 2PFMA 1W27A 1HY0A 4C5UA 2E9FA 1TJWA 1K62A 3OCFA 1FUOA 1EB4A 4BABA 4MX2A 1Q5NA 3OCEA 1YFEA 4BAAA 3R6VA 2OHYA 2J91A 1JSWA 4NLEA 2RJRA 3NO9A 2PTQA 5EYVA 4NSLA 3GZHA 1TJVA 4EFCA 1HY1A 1RE5A 3KDYA 2O7DA 3CZOA 2FUSA 4APAA 2PTSA 1U16A 5EYTA 3C8TA 3TV2A 3E04A 1FUQA 1GK2A
chains in the Genus database with same CATH superfamily
3CRW1 3R6QA 4V2QA 4EEIA 2YIIA 1K7WA 2NYNA 5M0IA 4HGVA 1KQ7A 3NZ4A 1GKJA 1U15A 1T6JA 2O78A 5F91A 3RD8A 1TJUA 3KDZA 4APBA 2O7FA 1B8FA 4FLCA 1GK3A 1T6PA 2QGAB 5F92A 5H8WA 5M0JA 1C3CA 3CRVA 1J3UA 3RRPA 1DOFA 1I0AA 1DCNA 2O6YA 4ADLA 1FUPA 2X75A 2VD6A 1VDKA 1XMCA 1GKMA 5HW2A 2O7EA 2PTRA 1YISA 1TJ7A 4WNLA 1AUWA 3GTDA 3UNVA 3R6YA 4FFXA 2HVGA 2NYFA 1C3UA 1XLYA 4V2RA 3BHGA 2QVEA 3QBPA 2VSFA 1FURA 1XWOA 4ADMA 4C5RA 4A15A 4C6GA 5D6BA 1Y2MA 2RJSA 2O7BA 2FENA 4C5SA 4CQ5A 1XMDA 1YFMA 2PFMA 1W27A 1HY0A 4C5UA 2E9FA 1TJWA 1K62A 3OCFA 1FUOA 1EB4A 4BABA 4MX2A 1Q5NA 3OCEA 1YFEA 4BAAA 1XL7A 3R6VA 2OHYA 2J91A 1JSWA 4NLEA 2RJRA 3NO9A 2PTQA 5EYVA 4NSLA 3GZHA 1TJVA 4EFCA 1HY1A 1RE5A 3KDYA 2O7DA 3CZOA 2FUSA 2VL7A 4APAA 2FELA 2PTSA 1U16A 5EYTA 3C8TA 3TV2A 3E04A 1XL8A 1FUQA 1GK2A
chains in the Genus database with same CATH topology
3R6QA 4V2QA 4EEIA 2YIIA 1K7WA 2NYNA 4HGVA 1KQ7A 3NZ4A 1GKJA 1U15A 1T6JA 2O78A 5F91A 3RD8A 1TJUA 3KDZA 4APBA 2O7FA 1B8FA 4FLCA 1GK3A 1T6PA 2QGAB 5F92A 1C3CA 1J3UA 3RRPA 1DOFA 1I0AA 1DCNA 2O6YA 4ADLA 1FUPA 2X75A 2VD6A 1VDKA 1GKMA 5HW2A 2O7EA 2PTRA 1YISA 1TJ7A 1AUWA 3GTDA 3UNVA 3R6YA 4FFXA 2HVGA 2NYFA 1C3UA 4V2RA 3BHGA 2QVEA 3QBPA 1FURA 1XWOA 4ADMA 4C5RA 4C6GA 5D6BA 1Y2MA 2RJSA 2O7BA 4C5SA 4CQ5A 1YFMA 2PFMA 1W27A 1HY0A 4C5UA 2E9FA 1TJWA 1K62A 3OCFA 1FUOA 1EB4A 4BABA 4MX2A 1Q5NA 3OCEA 1YFEA 4BAAA 3R6VA 2OHYA 2J91A 1JSWA 4NLEA 2RJRA 3NO9A 2PTQA 5EYVA 4NSLA 3GZHA 1TJVA 4EFCA 1HY1A 1RE5A 3KDYA 2O7DA 3CZOA 2FUSA 4APAA 2PTSA 1U16A 5EYTA 3C8TA 3TV2A 3E04A 1FUQA 1GK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R6Q A;  4V2Q A;  4EEI A;  2YII A;  1K7W A;  2NYN A;  4HGV A;  1KQ7 A;  3NZ4 A;  1GKJ A;  1U15 A;  1T6J A;  2O78 A;  5F91 A;  3RD8 A;  1TJU A;  3KDZ A;  4APB A;  2O7F A;  1B8F A;  4FLC A;  1GK3 A;  1T6P A;  2QGA B;  5F92 A;  1C3C A;  1J3U A;  3RRP A;  1DOF A;  1I0A A;  1DCN A;  2O6Y A;  4ADL A;  1FUP A;  2X75 A;  2VD6 A;  1VDK A;  1GKM A;  5HW2 A;  2O7E A;  2PTR A;  1YIS A;  1TJ7 A;  1AUW A;  3GTD A;  3UNV A;  3R6Y A;  4FFX A;  2HVG A;  2NYF A;  1C3U A;  4V2R A;  3BHG A;  2QVE A;  3QBP A;  1FUR A;  1XWO A;  4ADM A;  4C5R A;  4C6G A;  5D6B A;  1Y2M A;  2RJS A;  2O7B A;  4C5S A;  4CQ5 A;  1YFM A;  2PFM A;  1W27 A;  1HY0 A;  4C5U A;  2E9F A;  1TJW A;  1K62 A;  3OCF A;  1FUO A;  1EB4 A;  4BAB A;  4MX2 A;  1Q5N A;  3OCE A;  1YFE A;  4BAA A;  3R6V A;  2OHY A;  2J91 A;  1JSW A;  4NLE A;  2RJR A;  3NO9 A;  2PTQ A;  5EYV A;  4NSL A;  3GZH A;  1TJV A;  4EFC A;  1HY1 A;  1RE5 A;  3KDY A;  2O7D A;  3CZO A;  2FUS A;  4APA A;  2PTS A;  1U16 A;  5EYT A;  3C8T A;  3TV2 A;  3E04 A;  1FUQ A;  1GK2 A; 
#chains in the Genus database with same CATH topology
 3CRW 1;  3R6Q A;  4V2Q A;  4EEI A;  2YII A;  1K7W A;  2NYN A;  5M0I A;  4HGV A;  1KQ7 A;  3NZ4 A;  1GKJ A;  1U15 A;  1T6J A;  2O78 A;  5F91 A;  3RD8 A;  1TJU A;  3KDZ A;  4APB A;  2O7F A;  1B8F A;  4FLC A;  1GK3 A;  1T6P A;  2QGA B;  5F92 A;  5H8W A;  5M0J A;  1C3C A;  3CRV A;  1J3U A;  3RRP A;  1DOF A;  1I0A A;  1DCN A;  2O6Y A;  4ADL A;  1FUP A;  2X75 A;  2VD6 A;  1VDK A;  1XMC A;  1GKM A;  5HW2 A;  2O7E A;  2PTR A;  1YIS A;  1TJ7 A;  4WNL A;  1AUW A;  3GTD A;  3UNV A;  3R6Y A;  4FFX A;  2HVG A;  2NYF A;  1C3U A;  1XLY A;  4V2R A;  3BHG A;  2QVE A;  3QBP A;  2VSF A;  1FUR A;  1XWO A;  4ADM A;  4C5R A;  4A15 A;  4C6G A;  5D6B A;  1Y2M A;  2RJS A;  2O7B A;  2FEN A;  4C5S A;  4CQ5 A;  1XMD A;  1YFM A;  2PFM A;  1W27 A;  1HY0 A;  4C5U A;  2E9F A;  1TJW A;  1K62 A;  3OCF A;  1FUO A;  1EB4 A;  4BAB A;  4MX2 A;  1Q5N A;  3OCE A;  1YFE A;  4BAA A;  1XL7 A;  3R6V A;  2OHY A;  2J91 A;  1JSW A;  4NLE A;  2RJR A;  3NO9 A;  2PTQ A;  5EYV A;  4NSL A;  3GZH A;  1TJV A;  4EFC A;  1HY1 A;  1RE5 A;  3KDY A;  2O7D A;  3CZO A;  2FUS A;  2VL7 A;  4APA A;  2FEL A;  2PTS A;  1U16 A;  5EYT A;  3C8T A;  3TV2 A;  3E04 A;  1XL8 A;  1FUQ A;  1GK2 A; 
#chains in the Genus database with same CATH homology
 3R6Q A;  4V2Q A;  4EEI A;  2YII A;  1K7W A;  2NYN A;  4HGV A;  1KQ7 A;  3NZ4 A;  1GKJ A;  1U15 A;  1T6J A;  2O78 A;  5F91 A;  3RD8 A;  1TJU A;  3KDZ A;  4APB A;  2O7F A;  1B8F A;  4FLC A;  1GK3 A;  1T6P A;  2QGA B;  5F92 A;  1C3C A;  1J3U A;  3RRP A;  1DOF A;  1I0A A;  1DCN A;  2O6Y A;  4ADL A;  1FUP A;  2X75 A;  2VD6 A;  1VDK A;  1GKM A;  5HW2 A;  2O7E A;  2PTR A;  1YIS A;  1TJ7 A;  1AUW A;  3GTD A;  3UNV A;  3R6Y A;  4FFX A;  2HVG A;  2NYF A;  1C3U A;  4V2R A;  3BHG A;  2QVE A;  3QBP A;  1FUR A;  1XWO A;  4ADM A;  4C5R A;  4C6G A;  5D6B A;  1Y2M A;  2RJS A;  2O7B A;  4C5S A;  4CQ5 A;  1YFM A;  2PFM A;  1W27 A;  1HY0 A;  4C5U A;  2E9F A;  1TJW A;  1K62 A;  3OCF A;  1FUO A;  1EB4 A;  4BAB A;  4MX2 A;  1Q5N A;  3OCE A;  1YFE A;  4BAA A;  3R6V A;  2OHY A;  2J91 A;  1JSW A;  4NLE A;  2RJR A;  3NO9 A;  2PTQ A;  5EYV A;  4NSL A;  3GZH A;  1TJV A;  4EFC A;  1HY1 A;  1RE5 A;  3KDY A;  2O7D A;  3CZO A;  2FUS A;  4APA A;  2PTS A;  1U16 A;  5EYT A;  3C8T A;  3TV2 A;  3E04 A;  1FUQ A;  1GK2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...