2O7DA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with caffeate
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
total genus 193
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7dA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7dA02
2NYNA 3RRPA 3TV2A 1T6PA 1K7WA 2NYFA 3NZ4A 4HGVA 1FUPA 1YFEA 1HY0A 1AUWA 4NSLA 2PTSA 1DOFA 5EYVA 4C5SA 1J3UA 3E04A 2O6YA 4ADMA 1C3CA 4V2QA 2J91A 1T6JA 5F91A 1GK3A 4APAA 4EEIA 1VDKA 1FUOA 3QBPA 2PTQA 5D6BA 3KDZA 1K62A 4CQ5A 4C6GA 2O78A 3GZHA 4NLEA 3KDYA 3BHGA 4ADLA 1Q5NA 2RJRA 1JSWA 1EB4A 4C5RA 1XWOA 2OHYA 2VD6A 3OCFA 2O7DA 1W27A 2O7FA 3UNVA 2PTRA 1YISA 4C5UA 4EFCA 4V2RA 5EYTA 1I0AA 1U16A 3OCEA 3NO9A 2E9FA 3R6YA 1TJVA 2RJSA 1HY1A 3R6QA 1U15A 2O7BA 1TJWA 1KQ7A 1GKMA 5HW2A 2QGAB 2HVGA 2QVEA 1DCNA 1RE5A 3CZOA 3R6VA 3GTDA 1GK2A 1Y2MA 4APBA 4BABA 1FURA 1TJ7A 3RD8A 1B8FA 1GKJA 2O7EA 2X75A 2PFMA 2YIIA 4FLCA 3C8TA 5F92A 4MX2A 1YFMA 1FUQA 4BAAA 1TJUA 4FFXA 2FUSA 1C3UA
chains in the Genus database with same CATH superfamily
2NYNA 3RRPA 3TV2A 1T6PA 1K7WA 2NYFA 3NZ4A 4HGVA 1FUPA 1YFEA 1HY0A 1AUWA 4NSLA 2PTSA 2VL7A 1DOFA 5EYVA 4C5SA 1J3UA 3E04A 2O6YA 4ADMA 2FELA 1C3CA 4V2QA 1XL8A 2J91A 1T6JA 1XL7A 5F91A 1GK3A 4APAA 4EEIA 1VDKA 1XLYA 1FUOA 3QBPA 1XMDA 2PTQA 5D6BA 3KDZA 1K62A 4CQ5A 4C6GA 5H8WA 2O78A 5M0JA 3GZHA 4NLEA 3KDYA 3BHGA 4ADLA 1Q5NA 2RJRA 1XMCA 1JSWA 1EB4A 5M0IA 4C5RA 1XWOA 2OHYA 2VD6A 3OCFA 2O7DA 1W27A 2O7FA 3CRVA 3UNVA 2PTRA 1YISA 4C5UA 4EFCA 4V2RA 5EYTA 1I0AA 1U16A 3OCEA 3NO9A 2E9FA 3R6YA 1TJVA 2RJSA 1HY1A 3R6QA 1U15A 2O7BA 1TJWA 1KQ7A 1GKMA 5HW2A 4WNLA 2QGAB 2HVGA 2QVEA 1DCNA 1RE5A 3CZOA 3R6VA 3GTDA 1GK2A 1Y2MA 4APBA 4BABA 1FURA 1TJ7A 3RD8A 1B8FA 1GKJA 2O7EA 2X75A 2PFMA 2YIIA 4FLCA 4A15A 3C8TA 3CRW1 5F92A 4MX2A 1YFMA 2FENA 2VSFA 1FUQA 4BAAA 1TJUA 4FFXA 2FUSA 1C3UA
chains in the Genus database with same CATH topology
2NYNA 3RRPA 3TV2A 1T6PA 1K7WA 2NYFA 3NZ4A 4HGVA 1FUPA 1YFEA 1HY0A 1AUWA 4NSLA 2PTSA 1DOFA 5EYVA 4C5SA 1J3UA 3E04A 2O6YA 4ADMA 1C3CA 4V2QA 2J91A 1T6JA 5F91A 1GK3A 4APAA 4EEIA 1VDKA 1FUOA 3QBPA 2PTQA 5D6BA 3KDZA 1K62A 4CQ5A 4C6GA 2O78A 3GZHA 4NLEA 3KDYA 3BHGA 4ADLA 1Q5NA 2RJRA 1JSWA 1EB4A 4C5RA 1XWOA 2OHYA 2VD6A 3OCFA 2O7DA 1W27A 2O7FA 3UNVA 2PTRA 1YISA 4C5UA 4EFCA 4V2RA 5EYTA 1I0AA 1U16A 3OCEA 3NO9A 2E9FA 3R6YA 1TJVA 2RJSA 1HY1A 3R6QA 1U15A 2O7BA 1TJWA 1KQ7A 1GKMA 5HW2A 2QGAB 2HVGA 2QVEA 1DCNA 1RE5A 3CZOA 3R6VA 3GTDA 1GK2A 1Y2MA 4APBA 4BABA 1FURA 1TJ7A 3RD8A 1B8FA 1GKJA 2O7EA 2X75A 2PFMA 2YIIA 4FLCA 3C8TA 5F92A 4MX2A 1YFMA 1FUQA 4BAAA 1TJUA 4FFXA 2FUSA 1C3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYN A;  3RRP A;  3TV2 A;  1T6P A;  1K7W A;  2NYF A;  3NZ4 A;  4HGV A;  1FUP A;  1YFE A;  1HY0 A;  1AUW A;  4NSL A;  2PTS A;  1DOF A;  5EYV A;  4C5S A;  1J3U A;  3E04 A;  2O6Y A;  4ADM A;  1C3C A;  4V2Q A;  2J91 A;  1T6J A;  5F91 A;  1GK3 A;  4APA A;  4EEI A;  1VDK A;  1FUO A;  3QBP A;  2PTQ A;  5D6B A;  3KDZ A;  1K62 A;  4CQ5 A;  4C6G A;  2O78 A;  3GZH A;  4NLE A;  3KDY A;  3BHG A;  4ADL A;  1Q5N A;  2RJR A;  1JSW A;  1EB4 A;  4C5R A;  1XWO A;  2OHY A;  2VD6 A;  3OCF A;  2O7D A;  1W27 A;  2O7F A;  3UNV A;  2PTR A;  1YIS A;  4C5U A;  4EFC A;  4V2R A;  5EYT A;  1I0A A;  1U16 A;  3OCE A;  3NO9 A;  2E9F A;  3R6Y A;  1TJV A;  2RJS A;  1HY1 A;  3R6Q A;  1U15 A;  2O7B A;  1TJW A;  1KQ7 A;  1GKM A;  5HW2 A;  2QGA B;  2HVG A;  2QVE A;  1DCN A;  1RE5 A;  3CZO A;  3R6V A;  3GTD A;  1GK2 A;  1Y2M A;  4APB A;  4BAB A;  1FUR A;  1TJ7 A;  3RD8 A;  1B8F A;  1GKJ A;  2O7E A;  2X75 A;  2PFM A;  2YII A;  4FLC A;  3C8T A;  5F92 A;  4MX2 A;  1YFM A;  1FUQ A;  4BAA A;  1TJU A;  4FFX A;  2FUS A;  1C3U A; 
#chains in the Genus database with same CATH topology
 2NYN A;  3RRP A;  3TV2 A;  1T6P A;  1K7W A;  2NYF A;  3NZ4 A;  4HGV A;  1FUP A;  1YFE A;  1HY0 A;  1AUW A;  4NSL A;  2PTS A;  2VL7 A;  1DOF A;  5EYV A;  4C5S A;  1J3U A;  3E04 A;  2O6Y A;  4ADM A;  2FEL A;  1C3C A;  4V2Q A;  1XL8 A;  2J91 A;  1T6J A;  1XL7 A;  5F91 A;  1GK3 A;  4APA A;  4EEI A;  1VDK A;  1XLY A;  1FUO A;  3QBP A;  1XMD A;  2PTQ A;  5D6B A;  3KDZ A;  1K62 A;  4CQ5 A;  4C6G A;  5H8W A;  2O78 A;  5M0J A;  3GZH A;  4NLE A;  3KDY A;  3BHG A;  4ADL A;  1Q5N A;  2RJR A;  1XMC A;  1JSW A;  1EB4 A;  5M0I A;  4C5R A;  1XWO A;  2OHY A;  2VD6 A;  3OCF A;  2O7D A;  1W27 A;  2O7F A;  3CRV A;  3UNV A;  2PTR A;  1YIS A;  4C5U A;  4EFC A;  4V2R A;  5EYT A;  1I0A A;  1U16 A;  3OCE A;  3NO9 A;  2E9F A;  3R6Y A;  1TJV A;  2RJS A;  1HY1 A;  3R6Q A;  1U15 A;  2O7B A;  1TJW A;  1KQ7 A;  1GKM A;  5HW2 A;  4WNL A;  2QGA B;  2HVG A;  2QVE A;  1DCN A;  1RE5 A;  3CZO A;  3R6V A;  3GTD A;  1GK2 A;  1Y2M A;  4APB A;  4BAB A;  1FUR A;  1TJ7 A;  3RD8 A;  1B8F A;  1GKJ A;  2O7E A;  2X75 A;  2PFM A;  2YII A;  4FLC A;  4A15 A;  3C8T A;  3CRW 1;  5F92 A;  4MX2 A;  1YFM A;  2FEN A;  2VSF A;  1FUQ A;  4BAA A;  1TJU A;  4FFX A;  2FUS A;  1C3U A; 
#chains in the Genus database with same CATH homology
 2NYN A;  3RRP A;  3TV2 A;  1T6P A;  1K7W A;  2NYF A;  3NZ4 A;  4HGV A;  1FUP A;  1YFE A;  1HY0 A;  1AUW A;  4NSL A;  2PTS A;  1DOF A;  5EYV A;  4C5S A;  1J3U A;  3E04 A;  2O6Y A;  4ADM A;  1C3C A;  4V2Q A;  2J91 A;  1T6J A;  5F91 A;  1GK3 A;  4APA A;  4EEI A;  1VDK A;  1FUO A;  3QBP A;  2PTQ A;  5D6B A;  3KDZ A;  1K62 A;  4CQ5 A;  4C6G A;  2O78 A;  3GZH A;  4NLE A;  3KDY A;  3BHG A;  4ADL A;  1Q5N A;  2RJR A;  1JSW A;  1EB4 A;  4C5R A;  1XWO A;  2OHY A;  2VD6 A;  3OCF A;  2O7D A;  1W27 A;  2O7F A;  3UNV A;  2PTR A;  1YIS A;  4C5U A;  4EFC A;  4V2R A;  5EYT A;  1I0A A;  1U16 A;  3OCE A;  3NO9 A;  2E9F A;  3R6Y A;  1TJV A;  2RJS A;  1HY1 A;  3R6Q A;  1U15 A;  2O7B A;  1TJW A;  1KQ7 A;  1GKM A;  5HW2 A;  2QGA B;  2HVG A;  2QVE A;  1DCN A;  1RE5 A;  3CZO A;  3R6V A;  3GTD A;  1GK2 A;  1Y2M A;  4APB A;  4BAB A;  1FUR A;  1TJ7 A;  3RD8 A;  1B8F A;  1GKJ A;  2O7E A;  2X75 A;  2PFM A;  2YII A;  4FLC A;  3C8T A;  5F92 A;  4MX2 A;  1YFM A;  1FUQ A;  4BAA A;  1TJU A;  4FFX A;  2FUS A;  1C3U A; 
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