2O7DA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with caffeate
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
515
structure length
514
Chain Sequence
b'PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Putative histidine ammonia-lyase
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
total genus 193
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7dA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7dA02
1DOFA 1GKJA 4EEIA 1FURA 1XWOA 4FFXA 1HY0A 3KDYA 2QGAB 1U15A 4APAA 2PFMA 4MX2A 4C6GA 2YIIA 4HGVA 4ADLA 3NO9A 3QBPA 2OHYA 1YISA 2PTRA 3TV2A 1TJWA 1KQ7A 2RJSA 4V2RA 3RRPA 1GK2A 2E9FA 2VD6A 1C3UA 1GKMA 1TJVA 4CQ5A 1K7WA 5EYVA 5F91A 1TJ7A 1JSWA 3R6YA 3OCEA 3E04A 1FUOA 2O7EA 1J3UA 4NLEA 4EFCA 5F92A 2FUSA 2O7BA 3KDZA 1Y2MA 1YFMA 1FUPA 2RJRA 4FLCA 2NYFA 2PTSA 2X75A 1FUQA 1GK3A 3UNVA 2O78A 3BHGA 1EB4A 2NYNA 2J91A 2HVGA 1B8FA 2O6YA 4C5SA 4NSLA 3GZHA 1VDKA 1K62A 2O7DA 5EYTA 4C5RA 1DCNA 2O7FA 3OCFA 1Q5NA 1T6JA 1C3CA 3CZOA 1YFEA 1AUWA 3GTDA 2QVEA 2PTQA 4BABA 1T6PA 5D6BA 1HY1A 1I0AA 3R6VA 4C5UA 3C8TA 1TJUA 1RE5A 3RD8A 1U16A 5HW2A 3NZ4A 4BAAA 4APBA 3R6QA 4ADMA 4V2QA 1W27A
chains in the Genus database with same CATH superfamily
1DOFA 1GKJA 4EEIA 1XMDA 1XLYA 1FURA 1XWOA 1HY0A 2QGAB 1U15A 3KDYA 4FFXA 4APAA 2PFMA 4MX2A 4C6GA 2YIIA 4HGVA 2FENA 4ADLA 3NO9A 3QBPA 2OHYA 1YISA 2PTRA 3TV2A 1TJWA 3CRW1 1KQ7A 5H8WA 2RJSA 4V2RA 3RRPA 1GK2A 2E9FA 2VD6A 1C3UA 1GKMA 1TJVA 4CQ5A 1K7WA 5EYVA 5F91A 1TJ7A 1JSWA 3R6YA 3OCEA 5M0JA 3E04A 1FUOA 2O7EA 1J3UA 4NLEA 4EFCA 5F92A 2FUSA 2O7BA 3KDZA 1Y2MA 1YFMA 1FUPA 2RJRA 4FLCA 2NYFA 2PTSA 2X75A 2FELA 1FUQA 1GK3A 3UNVA 2O78A 3BHGA 4A15A 1EB4A 2NYNA 2J91A 1XMCA 2HVGA 1B8FA 2O6YA 4C5SA 4NSLA 3CRVA 3GZHA 1VDKA 1K62A 1XL8A 2O7DA 5EYTA 4C5RA 1DCNA 2O7FA 1XL7A 3OCFA 1Q5NA 1T6JA 1C3CA 3CZOA 1YFEA 1AUWA 3GTDA 2QVEA 2PTQA 4BABA 1T6PA 5D6BA 1HY1A 1I0AA 3R6VA 4C5UA 3C8TA 1TJUA 1RE5A 3RD8A 5M0IA 1U16A 5HW2A 3NZ4A 4BAAA 2VL7A 4APBA 3R6QA 2VSFA 4ADMA 4V2QA 4WNLA 1W27A
chains in the Genus database with same CATH topology
1DOFA 1GKJA 4EEIA 1FURA 1XWOA 4FFXA 1HY0A 3KDYA 2QGAB 1U15A 4APAA 2PFMA 4MX2A 4C6GA 2YIIA 4HGVA 4ADLA 3NO9A 3QBPA 2OHYA 1YISA 2PTRA 3TV2A 1TJWA 1KQ7A 2RJSA 4V2RA 3RRPA 1GK2A 2E9FA 2VD6A 1C3UA 1GKMA 1TJVA 4CQ5A 1K7WA 5EYVA 5F91A 1TJ7A 1JSWA 3R6YA 3OCEA 3E04A 1FUOA 2O7EA 1J3UA 4NLEA 4EFCA 5F92A 2FUSA 2O7BA 3KDZA 1Y2MA 1YFMA 1FUPA 2RJRA 4FLCA 2NYFA 2PTSA 2X75A 1FUQA 1GK3A 3UNVA 2O78A 3BHGA 1EB4A 2NYNA 2J91A 2HVGA 1B8FA 2O6YA 4C5SA 4NSLA 3GZHA 1VDKA 1K62A 2O7DA 5EYTA 4C5RA 1DCNA 2O7FA 3OCFA 1Q5NA 1T6JA 1C3CA 3CZOA 1YFEA 1AUWA 3GTDA 2QVEA 2PTQA 4BABA 1T6PA 5D6BA 1HY1A 1I0AA 3R6VA 4C5UA 3C8TA 1TJUA 1RE5A 3RD8A 1U16A 5HW2A 3NZ4A 4BAAA 4APBA 3R6QA 4ADMA 4V2QA 1W27A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DOF A;  1GKJ A;  4EEI A;  1FUR A;  1XWO A;  4FFX A;  1HY0 A;  3KDY A;  2QGA B;  1U15 A;  4APA A;  2PFM A;  4MX2 A;  4C6G A;  2YII A;  4HGV A;  4ADL A;  3NO9 A;  3QBP A;  2OHY A;  1YIS A;  2PTR A;  3TV2 A;  1TJW A;  1KQ7 A;  2RJS A;  4V2R A;  3RRP A;  1GK2 A;  2E9F A;  2VD6 A;  1C3U A;  1GKM A;  1TJV A;  4CQ5 A;  1K7W A;  5EYV A;  5F91 A;  1TJ7 A;  1JSW A;  3R6Y A;  3OCE A;  3E04 A;  1FUO A;  2O7E A;  1J3U A;  4NLE A;  4EFC A;  5F92 A;  2FUS A;  2O7B A;  3KDZ A;  1Y2M A;  1YFM A;  1FUP A;  2RJR A;  4FLC A;  2NYF A;  2PTS A;  2X75 A;  1FUQ A;  1GK3 A;  3UNV A;  2O78 A;  3BHG A;  1EB4 A;  2NYN A;  2J91 A;  2HVG A;  1B8F A;  2O6Y A;  4C5S A;  4NSL A;  3GZH A;  1VDK A;  1K62 A;  2O7D A;  5EYT A;  4C5R A;  1DCN A;  2O7F A;  3OCF A;  1Q5N A;  1T6J A;  1C3C A;  3CZO A;  1YFE A;  1AUW A;  3GTD A;  2QVE A;  2PTQ A;  4BAB A;  1T6P A;  5D6B A;  1HY1 A;  1I0A A;  3R6V A;  4C5U A;  3C8T A;  1TJU A;  1RE5 A;  3RD8 A;  1U16 A;  5HW2 A;  3NZ4 A;  4BAA A;  4APB A;  3R6Q A;  4ADM A;  4V2Q A;  1W27 A; 
#chains in the Genus database with same CATH topology
 1DOF A;  1GKJ A;  4EEI A;  1XMD A;  1XLY A;  1FUR A;  1XWO A;  1HY0 A;  2QGA B;  1U15 A;  3KDY A;  4FFX A;  4APA A;  2PFM A;  4MX2 A;  4C6G A;  2YII A;  4HGV A;  2FEN A;  4ADL A;  3NO9 A;  3QBP A;  2OHY A;  1YIS A;  2PTR A;  3TV2 A;  1TJW A;  3CRW 1;  1KQ7 A;  5H8W A;  2RJS A;  4V2R A;  3RRP A;  1GK2 A;  2E9F A;  2VD6 A;  1C3U A;  1GKM A;  1TJV A;  4CQ5 A;  1K7W A;  5EYV A;  5F91 A;  1TJ7 A;  1JSW A;  3R6Y A;  3OCE A;  5M0J A;  3E04 A;  1FUO A;  2O7E A;  1J3U A;  4NLE A;  4EFC A;  5F92 A;  2FUS A;  2O7B A;  3KDZ A;  1Y2M A;  1YFM A;  1FUP A;  2RJR A;  4FLC A;  2NYF A;  2PTS A;  2X75 A;  2FEL A;  1FUQ A;  1GK3 A;  3UNV A;  2O78 A;  3BHG A;  4A15 A;  1EB4 A;  2NYN A;  2J91 A;  1XMC A;  2HVG A;  1B8F A;  2O6Y A;  4C5S A;  4NSL A;  3CRV A;  3GZH A;  1VDK A;  1K62 A;  1XL8 A;  2O7D A;  5EYT A;  4C5R A;  1DCN A;  2O7F A;  1XL7 A;  3OCF A;  1Q5N A;  1T6J A;  1C3C A;  3CZO A;  1YFE A;  1AUW A;  3GTD A;  2QVE A;  2PTQ A;  4BAB A;  1T6P A;  5D6B A;  1HY1 A;  1I0A A;  3R6V A;  4C5U A;  3C8T A;  1TJU A;  1RE5 A;  3RD8 A;  5M0I A;  1U16 A;  5HW2 A;  3NZ4 A;  4BAA A;  2VL7 A;  4APB A;  3R6Q A;  2VSF A;  4ADM A;  4V2Q A;  4WNL A;  1W27 A; 
#chains in the Genus database with same CATH homology
 1DOF A;  1GKJ A;  4EEI A;  1FUR A;  1XWO A;  4FFX A;  1HY0 A;  3KDY A;  2QGA B;  1U15 A;  4APA A;  2PFM A;  4MX2 A;  4C6G A;  2YII A;  4HGV A;  4ADL A;  3NO9 A;  3QBP A;  2OHY A;  1YIS A;  2PTR A;  3TV2 A;  1TJW A;  1KQ7 A;  2RJS A;  4V2R A;  3RRP A;  1GK2 A;  2E9F A;  2VD6 A;  1C3U A;  1GKM A;  1TJV A;  4CQ5 A;  1K7W A;  5EYV A;  5F91 A;  1TJ7 A;  1JSW A;  3R6Y A;  3OCE A;  3E04 A;  1FUO A;  2O7E A;  1J3U A;  4NLE A;  4EFC A;  5F92 A;  2FUS A;  2O7B A;  3KDZ A;  1Y2M A;  1YFM A;  1FUP A;  2RJR A;  4FLC A;  2NYF A;  2PTS A;  2X75 A;  1FUQ A;  1GK3 A;  3UNV A;  2O78 A;  3BHG A;  1EB4 A;  2NYN A;  2J91 A;  2HVG A;  1B8F A;  2O6Y A;  4C5S A;  4NSL A;  3GZH A;  1VDK A;  1K62 A;  2O7D A;  5EYT A;  4C5R A;  1DCN A;  2O7F A;  3OCF A;  1Q5N A;  1T6J A;  1C3C A;  3CZO A;  1YFE A;  1AUW A;  3GTD A;  2QVE A;  2PTQ A;  4BAB A;  1T6P A;  5D6B A;  1HY1 A;  1I0A A;  3R6V A;  4C5U A;  3C8T A;  1TJU A;  1RE5 A;  3RD8 A;  1U16 A;  5HW2 A;  3NZ4 A;  4BAA A;  4APB A;  3R6Q A;  4ADM A;  4V2Q A;  1W27 A; 
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