2O7DA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with caffeate
Total Genus 193
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
193
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Putative histidine ammonia-lyase
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
total genus 193
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7dA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7dA02
4CQ5A 1K7WA 2O78A 1HY0A 1XWOA 1AUWA 4ADMA 3OCEA 4C5UA 5F91A 2O7FA 1T6PA 2O7EA 3RRPA 4ADLA 3BHGA 5D6BA 5EYVA 1RE5A 3GZHA 1YFMA 3QBPA 1C3CA 1DCNA 3CZOA 2PFMA 4EEIA 5F92A 1GK3A 1HY1A 1FURA 1DOFA 4FFXA 1Y2MA 4BABA 1JSWA 3NZ4A 2FUSA 3NO9A 2VD6A 2O7BA 1TJUA 4FLCA 3R6YA 3KDYA 3C8TA 2J91A 2HVGA 2PTRA 4V2RA 3KDZA 2RJRA 1YISA 1W27A 1Q5NA 1FUPA 4APAA 2NYNA 2NYFA 3R6QA 1B8FA 1I0AA 1VDKA 1TJVA 1U16A 4BAAA 3GTDA 2O6YA 5HW2A 1FUOA 1C3UA 1YFEA 4C5RA 1GK2A 2PTSA 1GKJA 1EB4A 2YIIA 1U15A 1GKMA 4EFCA 1TJ7A 2E9FA 4NLEA 2QVEA 4APBA 3UNVA 2PTQA 1FUQA 4C6GA 4V2QA 1TJWA 1T6JA 2O7DA 3E04A 4HGVA 2QGAB 4MX2A 3R6VA 3RD8A 1K62A 3OCFA 5EYTA 4C5SA 2OHYA 3TV2A 2X75A 2RJSA 1KQ7A 4NSLA 1J3UA
chains in the Genus database with same CATH superfamily
4CQ5A 1XMCA 1K7WA 2O78A 1HY0A 1XWOA 1AUWA 4ADMA 3OCEA 4C5UA 5F91A 2O7FA 1T6PA 2O7EA 3RRPA 4ADLA 3BHGA 5D6BA 5M0IA 5EYVA 2VL7A 3CRW1 1RE5A 3GZHA 1YFMA 3QBPA 1C3CA 1DCNA 3CZOA 2PFMA 4EEIA 5F92A 1GK3A 1HY1A 1FURA 1DOFA 4FFXA 1XL7A 1Y2MA 4BABA 1JSWA 3NZ4A 2FUSA 3NO9A 2VD6A 2O7BA 1TJUA 4FLCA 3R6YA 1XLYA 3KDYA 3C8TA 2J91A 2HVGA 2PTRA 4V2RA 3KDZA 4WNLA 2RJRA 1YISA 1W27A 1Q5NA 1FUPA 4APAA 2NYNA 2NYFA 3R6QA 1B8FA 1I0AA 2FENA 1VDKA 1TJVA 1U16A 1XL8A 4BAAA 3GTDA 2O6YA 4A15A 5HW2A 1FUOA 1C3UA 1YFEA 4C5RA 1GK2A 2PTSA 2VSFA 1GKJA 1EB4A 1XMDA 2YIIA 1U15A 1GKMA 4EFCA 1TJ7A 2E9FA 4NLEA 2QVEA 4APBA 5M0JA 3UNVA 2PTQA 1FUQA 4C6GA 5H8WA 4V2QA 1TJWA 1T6JA 3CRVA 2FELA 2O7DA 3E04A 4HGVA 2QGAB 4MX2A 3R6VA 3RD8A 1K62A 3OCFA 5EYTA 4C5SA 2OHYA 3TV2A 2X75A 2RJSA 1KQ7A 4NSLA 1J3UA
chains in the Genus database with same CATH topology
4CQ5A 1K7WA 2O78A 1HY0A 1XWOA 1AUWA 4ADMA 3OCEA 4C5UA 5F91A 2O7FA 1T6PA 2O7EA 3RRPA 4ADLA 3BHGA 5D6BA 5EYVA 1RE5A 3GZHA 1YFMA 3QBPA 1C3CA 1DCNA 3CZOA 2PFMA 4EEIA 5F92A 1GK3A 1HY1A 1FURA 1DOFA 4FFXA 1Y2MA 4BABA 1JSWA 3NZ4A 2FUSA 3NO9A 2VD6A 2O7BA 1TJUA 4FLCA 3R6YA 3KDYA 3C8TA 2J91A 2HVGA 2PTRA 4V2RA 3KDZA 2RJRA 1YISA 1W27A 1Q5NA 1FUPA 4APAA 2NYNA 2NYFA 3R6QA 1B8FA 1I0AA 1VDKA 1TJVA 1U16A 4BAAA 3GTDA 2O6YA 5HW2A 1FUOA 1C3UA 1YFEA 4C5RA 1GK2A 2PTSA 1GKJA 1EB4A 2YIIA 1U15A 1GKMA 4EFCA 1TJ7A 2E9FA 4NLEA 2QVEA 4APBA 3UNVA 2PTQA 1FUQA 4C6GA 4V2QA 1TJWA 1T6JA 2O7DA 3E04A 4HGVA 2QGAB 4MX2A 3R6VA 3RD8A 1K62A 3OCFA 5EYTA 4C5SA 2OHYA 3TV2A 2X75A 2RJSA 1KQ7A 4NSLA 1J3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CQ5 A;  1K7W A;  2O78 A;  1HY0 A;  1XWO A;  1AUW A;  4ADM A;  3OCE A;  4C5U A;  5F91 A;  2O7F A;  1T6P A;  2O7E A;  3RRP A;  4ADL A;  3BHG A;  5D6B A;  5EYV A;  1RE5 A;  3GZH A;  1YFM A;  3QBP A;  1C3C A;  1DCN A;  3CZO A;  2PFM A;  4EEI A;  5F92 A;  1GK3 A;  1HY1 A;  1FUR A;  1DOF A;  4FFX A;  1Y2M A;  4BAB A;  1JSW A;  3NZ4 A;  2FUS A;  3NO9 A;  2VD6 A;  2O7B A;  1TJU A;  4FLC A;  3R6Y A;  3KDY A;  3C8T A;  2J91 A;  2HVG A;  2PTR A;  4V2R A;  3KDZ A;  2RJR A;  1YIS A;  1W27 A;  1Q5N A;  1FUP A;  4APA A;  2NYN A;  2NYF A;  3R6Q A;  1B8F A;  1I0A A;  1VDK A;  1TJV A;  1U16 A;  4BAA A;  3GTD A;  2O6Y A;  5HW2 A;  1FUO A;  1C3U A;  1YFE A;  4C5R A;  1GK2 A;  2PTS A;  1GKJ A;  1EB4 A;  2YII A;  1U15 A;  1GKM A;  4EFC A;  1TJ7 A;  2E9F A;  4NLE A;  2QVE A;  4APB A;  3UNV A;  2PTQ A;  1FUQ A;  4C6G A;  4V2Q A;  1TJW A;  1T6J A;  2O7D A;  3E04 A;  4HGV A;  2QGA B;  4MX2 A;  3R6V A;  3RD8 A;  1K62 A;  3OCF A;  5EYT A;  4C5S A;  2OHY A;  3TV2 A;  2X75 A;  2RJS A;  1KQ7 A;  4NSL A;  1J3U A; 
#chains in the Genus database with same CATH topology
 4CQ5 A;  1XMC A;  1K7W A;  2O78 A;  1HY0 A;  1XWO A;  1AUW A;  4ADM A;  3OCE A;  4C5U A;  5F91 A;  2O7F A;  1T6P A;  2O7E A;  3RRP A;  4ADL A;  3BHG A;  5D6B A;  5M0I A;  5EYV A;  2VL7 A;  3CRW 1;  1RE5 A;  3GZH A;  1YFM A;  3QBP A;  1C3C A;  1DCN A;  3CZO A;  2PFM A;  4EEI A;  5F92 A;  1GK3 A;  1HY1 A;  1FUR A;  1DOF A;  4FFX A;  1XL7 A;  1Y2M A;  4BAB A;  1JSW A;  3NZ4 A;  2FUS A;  3NO9 A;  2VD6 A;  2O7B A;  1TJU A;  4FLC A;  3R6Y A;  1XLY A;  3KDY A;  3C8T A;  2J91 A;  2HVG A;  2PTR A;  4V2R A;  3KDZ A;  4WNL A;  2RJR A;  1YIS A;  1W27 A;  1Q5N A;  1FUP A;  4APA A;  2NYN A;  2NYF A;  3R6Q A;  1B8F A;  1I0A A;  2FEN A;  1VDK A;  1TJV A;  1U16 A;  1XL8 A;  4BAA A;  3GTD A;  2O6Y A;  4A15 A;  5HW2 A;  1FUO A;  1C3U A;  1YFE A;  4C5R A;  1GK2 A;  2PTS A;  2VSF A;  1GKJ A;  1EB4 A;  1XMD A;  2YII A;  1U15 A;  1GKM A;  4EFC A;  1TJ7 A;  2E9F A;  4NLE A;  2QVE A;  4APB A;  5M0J A;  3UNV A;  2PTQ A;  1FUQ A;  4C6G A;  5H8W A;  4V2Q A;  1TJW A;  1T6J A;  3CRV A;  2FEL A;  2O7D A;  3E04 A;  4HGV A;  2QGA B;  4MX2 A;  3R6V A;  3RD8 A;  1K62 A;  3OCF A;  5EYT A;  4C5S A;  2OHY A;  3TV2 A;  2X75 A;  2RJS A;  1KQ7 A;  4NSL A;  1J3U A; 
#chains in the Genus database with same CATH homology
 4CQ5 A;  1K7W A;  2O78 A;  1HY0 A;  1XWO A;  1AUW A;  4ADM A;  3OCE A;  4C5U A;  5F91 A;  2O7F A;  1T6P A;  2O7E A;  3RRP A;  4ADL A;  3BHG A;  5D6B A;  5EYV A;  1RE5 A;  3GZH A;  1YFM A;  3QBP A;  1C3C A;  1DCN A;  3CZO A;  2PFM A;  4EEI A;  5F92 A;  1GK3 A;  1HY1 A;  1FUR A;  1DOF A;  4FFX A;  1Y2M A;  4BAB A;  1JSW A;  3NZ4 A;  2FUS A;  3NO9 A;  2VD6 A;  2O7B A;  1TJU A;  4FLC A;  3R6Y A;  3KDY A;  3C8T A;  2J91 A;  2HVG A;  2PTR A;  4V2R A;  3KDZ A;  2RJR A;  1YIS A;  1W27 A;  1Q5N A;  1FUP A;  4APA A;  2NYN A;  2NYF A;  3R6Q A;  1B8F A;  1I0A A;  1VDK A;  1TJV A;  1U16 A;  4BAA A;  3GTD A;  2O6Y A;  5HW2 A;  1FUO A;  1C3U A;  1YFE A;  4C5R A;  1GK2 A;  2PTS A;  1GKJ A;  1EB4 A;  2YII A;  1U15 A;  1GKM A;  4EFC A;  1TJ7 A;  2E9F A;  4NLE A;  2QVE A;  4APB A;  3UNV A;  2PTQ A;  1FUQ A;  4C6G A;  4V2Q A;  1TJW A;  1T6J A;  2O7D A;  3E04 A;  4HGV A;  2QGA B;  4MX2 A;  3R6V A;  3RD8 A;  1K62 A;  3OCF A;  5EYT A;  4C5S A;  2OHY A;  3TV2 A;  2X75 A;  2RJS A;  1KQ7 A;  4NSL A;  1J3U A; 
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