2NYNA

Crystal structure of phenylalanine ammonia-lyase from anabaena variabilis
Total Genus 201
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
201
sequence length
537
structure length
511
Chain Sequence
b'NVIIGNQKLTINDVARVARNGTLVSLTNNTDILQGIQASCDYINNAVESGISREQASELQTNLVWFLKTGAGNKLPLADVRAAMLLRANSHMRGASGIRLELIKRMEIFLNAGVTPYVYEFGSIGDLVPLSYITGSLIGLDPSFKVDFNGKEMDAPTALRQLNLSPLTLLPKEGLAMMNGTSVMTGIAANCVYDTQILTAIAMGVHALDIQALNGTNQSFHPFIHNSKPHPGQLWAADQMISLLANSQLVRDELDGKIQDRYSLRCLPQYLGPIVDGISQIAKQIEIEINSVTDNPLIDVDNQASYHGGNFLGQYVGMGMDHLRYYIGLLAKHLDVQIALLASPEFSNGLPPSLLGNRERKVNMGLKGLQICGNSIMPLLTFYGNSIADRFPTHAEQFNQNINSQGYTSATLARRSVDIFQNYVAIALMFGVQAVDLRTYKKTGHYDARACLSPATERLYSAVRHVVGQKPTSDRPYIWNDNEQGLDEHIARISADIAAGGVIVQAVQDIL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Phenylalanine/histidine ammonia-lyase
publication title Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
pubmed doi rcsb
source organism Anabaena variabilis
molecule tags Lyase
total genus 201
structure length 511
sequence length 537
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2006-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2nynA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2nynA02
3BHGA 1DOFA 4BABA 3QBPA 1DCNA 2YIIA 1EB4A 2X75A 4C5SA 1J3UA 5EYVA 2OHYA 1VDKA 3KDZA 1C3UA 2QVEA 3NZ4A 3GZHA 4HGVA 1FUQA 2PTSA 2FUSA 5HW2A 3UNVA 4EFCA 4NSLA 2RJSA 3C8TA 1Q5NA 4APAA 1YISA 1I0AA 3GTDA 4V2RA 4MX2A 4FFXA 1HY0A 1JSWA 2O7BA 3KDYA 1YFMA 4C5UA 1U15A 4FLCA 3E04A 1C3CA 4C6GA 1FUPA 1TJUA 2O7DA 4BAAA 3TV2A 2O6YA 4APBA 4EEIA 2NYFA 4C5RA 2E9FA 2O78A 3OCEA 1HY1A 1GKMA 4ADMA 2O7FA 1FURA 2HVGA 4NLEA 2PFMA 1GKJA 1Y2MA 3R6VA 1AUWA 1XWOA 5EYTA 5F92A 2PTQA 3OCFA 1KQ7A 1K62A 1W27A 3RRPA 1YFEA 4ADLA 5F91A 1GK2A 1TJWA 4V2QA 2O7EA 3NO9A 1U16A 3CZOA 1T6JA 2PTRA 3RD8A 1K7WA 5D6BA 2VD6A 2RJRA 1FUOA 2QGAB 3R6QA 2J91A 1B8FA 1TJ7A 1T6PA 1GK3A 2NYNA 4CQ5A 3R6YA 1TJVA 1RE5A
chains in the Genus database with same CATH superfamily
3BHGA 1DOFA 4BABA 3QBPA 4A15A 1DCNA 2YIIA 2FELA 1EB4A 2X75A 4C5SA 1J3UA 5EYVA 2OHYA 1VDKA 2FENA 3KDZA 1C3UA 2QVEA 3NZ4A 3GZHA 4HGVA 1FUQA 2PTSA 2FUSA 5HW2A 3UNVA 4EFCA 4NSLA 2RJSA 3C8TA 1Q5NA 4APAA 1YISA 1I0AA 3GTDA 4V2RA 3CRVA 4MX2A 4FFXA 1XMCA 1HY0A 1JSWA 2O7BA 3KDYA 1XLYA 1YFMA 4C5UA 1U15A 4FLCA 3E04A 3CRW1 1C3CA 4C6GA 1FUPA 1TJUA 2O7DA 4BAAA 5M0JA 3TV2A 2O6YA 4APBA 4EEIA 2NYFA 4C5RA 2E9FA 2O78A 3OCEA 1HY1A 1GKMA 2VSFA 4ADMA 2O7FA 1FURA 2HVGA 4NLEA 2PFMA 1GKJA 1Y2MA 3R6VA 1AUWA 1XMDA 1XWOA 2VL7A 5EYTA 5F92A 2PTQA 3OCFA 1KQ7A 1K62A 1W27A 3RRPA 1YFEA 4ADLA 5F91A 1GK2A 1TJWA 4V2QA 2O7EA 3NO9A 1U16A 3CZOA 5H8WA 1T6JA 2PTRA 3RD8A 1K7WA 5D6BA 4WNLA 1XL7A 2VD6A 2RJRA 5M0IA 1FUOA 1XL8A 2QGAB 3R6QA 2J91A 1B8FA 1TJ7A 1T6PA 1GK3A 2NYNA 4CQ5A 3R6YA 1TJVA 1RE5A
chains in the Genus database with same CATH topology
3BHGA 1DOFA 4BABA 3QBPA 1DCNA 2YIIA 1EB4A 2X75A 4C5SA 1J3UA 5EYVA 2OHYA 1VDKA 3KDZA 1C3UA 2QVEA 3NZ4A 3GZHA 4HGVA 1FUQA 2PTSA 2FUSA 5HW2A 3UNVA 4EFCA 4NSLA 2RJSA 3C8TA 1Q5NA 4APAA 1YISA 1I0AA 3GTDA 4V2RA 4MX2A 4FFXA 1HY0A 1JSWA 2O7BA 3KDYA 1YFMA 4C5UA 1U15A 4FLCA 3E04A 1C3CA 4C6GA 1FUPA 1TJUA 2O7DA 4BAAA 3TV2A 2O6YA 4APBA 4EEIA 2NYFA 4C5RA 2E9FA 2O78A 3OCEA 1HY1A 1GKMA 4ADMA 2O7FA 1FURA 2HVGA 4NLEA 2PFMA 1GKJA 1Y2MA 3R6VA 1AUWA 1XWOA 5EYTA 5F92A 2PTQA 3OCFA 1KQ7A 1K62A 1W27A 3RRPA 1YFEA 4ADLA 5F91A 1GK2A 1TJWA 4V2QA 2O7EA 3NO9A 1U16A 3CZOA 1T6JA 2PTRA 3RD8A 1K7WA 5D6BA 2VD6A 2RJRA 1FUOA 2QGAB 3R6QA 2J91A 1B8FA 1TJ7A 1T6PA 1GK3A 2NYNA 4CQ5A 3R6YA 1TJVA 1RE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BHG A;  1DOF A;  4BAB A;  3QBP A;  1DCN A;  2YII A;  1EB4 A;  2X75 A;  4C5S A;  1J3U A;  5EYV A;  2OHY A;  1VDK A;  3KDZ A;  1C3U A;  2QVE A;  3NZ4 A;  3GZH A;  4HGV A;  1FUQ A;  2PTS A;  2FUS A;  5HW2 A;  3UNV A;  4EFC A;  4NSL A;  2RJS A;  3C8T A;  1Q5N A;  4APA A;  1YIS A;  1I0A A;  3GTD A;  4V2R A;  4MX2 A;  4FFX A;  1HY0 A;  1JSW A;  2O7B A;  3KDY A;  1YFM A;  4C5U A;  1U15 A;  4FLC A;  3E04 A;  1C3C A;  4C6G A;  1FUP A;  1TJU A;  2O7D A;  4BAA A;  3TV2 A;  2O6Y A;  4APB A;  4EEI A;  2NYF A;  4C5R A;  2E9F A;  2O78 A;  3OCE A;  1HY1 A;  1GKM A;  4ADM A;  2O7F A;  1FUR A;  2HVG A;  4NLE A;  2PFM A;  1GKJ A;  1Y2M A;  3R6V A;  1AUW A;  1XWO A;  5EYT A;  5F92 A;  2PTQ A;  3OCF A;  1KQ7 A;  1K62 A;  1W27 A;  3RRP A;  1YFE A;  4ADL A;  5F91 A;  1GK2 A;  1TJW A;  4V2Q A;  2O7E A;  3NO9 A;  1U16 A;  3CZO A;  1T6J A;  2PTR A;  3RD8 A;  1K7W A;  5D6B A;  2VD6 A;  2RJR A;  1FUO A;  2QGA B;  3R6Q A;  2J91 A;  1B8F A;  1TJ7 A;  1T6P A;  1GK3 A;  2NYN A;  4CQ5 A;  3R6Y A;  1TJV A;  1RE5 A; 
#chains in the Genus database with same CATH topology
 3BHG A;  1DOF A;  4BAB A;  3QBP A;  4A15 A;  1DCN A;  2YII A;  2FEL A;  1EB4 A;  2X75 A;  4C5S A;  1J3U A;  5EYV A;  2OHY A;  1VDK A;  2FEN A;  3KDZ A;  1C3U A;  2QVE A;  3NZ4 A;  3GZH A;  4HGV A;  1FUQ A;  2PTS A;  2FUS A;  5HW2 A;  3UNV A;  4EFC A;  4NSL A;  2RJS A;  3C8T A;  1Q5N A;  4APA A;  1YIS A;  1I0A A;  3GTD A;  4V2R A;  3CRV A;  4MX2 A;  4FFX A;  1XMC A;  1HY0 A;  1JSW A;  2O7B A;  3KDY A;  1XLY A;  1YFM A;  4C5U A;  1U15 A;  4FLC A;  3E04 A;  3CRW 1;  1C3C A;  4C6G A;  1FUP A;  1TJU A;  2O7D A;  4BAA A;  5M0J A;  3TV2 A;  2O6Y A;  4APB A;  4EEI A;  2NYF A;  4C5R A;  2E9F A;  2O78 A;  3OCE A;  1HY1 A;  1GKM A;  2VSF A;  4ADM A;  2O7F A;  1FUR A;  2HVG A;  4NLE A;  2PFM A;  1GKJ A;  1Y2M A;  3R6V A;  1AUW A;  1XMD A;  1XWO A;  2VL7 A;  5EYT A;  5F92 A;  2PTQ A;  3OCF A;  1KQ7 A;  1K62 A;  1W27 A;  3RRP A;  1YFE A;  4ADL A;  5F91 A;  1GK2 A;  1TJW A;  4V2Q A;  2O7E A;  3NO9 A;  1U16 A;  3CZO A;  5H8W A;  1T6J A;  2PTR A;  3RD8 A;  1K7W A;  5D6B A;  4WNL A;  1XL7 A;  2VD6 A;  2RJR A;  5M0I A;  1FUO A;  1XL8 A;  2QGA B;  3R6Q A;  2J91 A;  1B8F A;  1TJ7 A;  1T6P A;  1GK3 A;  2NYN A;  4CQ5 A;  3R6Y A;  1TJV A;  1RE5 A; 
#chains in the Genus database with same CATH homology
 3BHG A;  1DOF A;  4BAB A;  3QBP A;  1DCN A;  2YII A;  1EB4 A;  2X75 A;  4C5S A;  1J3U A;  5EYV A;  2OHY A;  1VDK A;  3KDZ A;  1C3U A;  2QVE A;  3NZ4 A;  3GZH A;  4HGV A;  1FUQ A;  2PTS A;  2FUS A;  5HW2 A;  3UNV A;  4EFC A;  4NSL A;  2RJS A;  3C8T A;  1Q5N A;  4APA A;  1YIS A;  1I0A A;  3GTD A;  4V2R A;  4MX2 A;  4FFX A;  1HY0 A;  1JSW A;  2O7B A;  3KDY A;  1YFM A;  4C5U A;  1U15 A;  4FLC A;  3E04 A;  1C3C A;  4C6G A;  1FUP A;  1TJU A;  2O7D A;  4BAA A;  3TV2 A;  2O6Y A;  4APB A;  4EEI A;  2NYF A;  4C5R A;  2E9F A;  2O78 A;  3OCE A;  1HY1 A;  1GKM A;  4ADM A;  2O7F A;  1FUR A;  2HVG A;  4NLE A;  2PFM A;  1GKJ A;  1Y2M A;  3R6V A;  1AUW A;  1XWO A;  5EYT A;  5F92 A;  2PTQ A;  3OCF A;  1KQ7 A;  1K62 A;  1W27 A;  3RRP A;  1YFE A;  4ADL A;  5F91 A;  1GK2 A;  1TJW A;  4V2Q A;  2O7E A;  3NO9 A;  1U16 A;  3CZO A;  1T6J A;  2PTR A;  3RD8 A;  1K7W A;  5D6B A;  2VD6 A;  2RJR A;  1FUO A;  2QGA B;  3R6Q A;  2J91 A;  1B8F A;  1TJ7 A;  1T6P A;  1GK3 A;  2NYN A;  4CQ5 A;  3R6Y A;  1TJV A;  1RE5 A; 
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