2NYNA

Crystal structure of phenylalanine ammonia-lyase from anabaena variabilis
Total Genus 201
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
201
sequence length
537
structure length
511
Chain Sequence
NVIIGNQKLTINDVARVARNGTLVSLTNNTDILQGIQASCDYINNAVESGISREQASELQTNLVWFLKTGAGNKLPLADVRAAMLLRANSHMRGASGIRLELIKRMEIFLNAGVTPYVYEFGSIGDLVPLSYITGSLIGLDPSFKVDFNGKEMDAPTALRQLNLSPLTLLPKEGLAMMNGTSVMTGIAANCVYDTQILTAIAMGVHALDIQALNGTNQSFHPFIHNSKPHPGQLWAADQMISLLANSQLVRDELDGKIQDRYSLRCLPQYLGPIVDGISQIAKQIEIEINSVTDNPLIDVDNQASYHGGNFLGQYVGMGMDHLRYYIGLLAKHLDVQIALLASPEFSNGLPPSLLGNRERKVNMGLKGLQICGNSIMPLLTFYGNSIADRFPTHAEQFNQNINSQGYTSATLARRSVDIFQNYVAIALMFGVQAVDLRTYKKTGHYDARACLSPATERLYSAVRHVVGQKPTSDRPYIWNDNEQGLDEHIARISADIAAGGVIVQAVQDIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Phenylalanine/histidine ammonia-lyase
publication title Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
pubmed doi rcsb
source organism Anabaena variabilis
molecule tags Lyase
total genus 201
structure length 511
sequence length 537
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2006-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2nynA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2nynA02
2E9FA 1EB4A 1GKJA 2O6YA 1FUQA 2FUSA 1GKMA 1HY1A 1W27A 2PTSA 3OCEA 4V2QA 3GZHA 1J3UA 2O7DA 1KQ7A 4ADLA 2RJRA 1K62A 5HW2A 1C3UA 3C8TA 4EEIA 1TJ7A 1U16A 3R6YA 3R6VA 4APBA 1JSWA 1DOFA 3RD8A 3RRPA 2PTQA 2NYNA 3KDYA 1GK3A 4FLCA 5F92A 2HVGA 3GTDA 4APAA 4ADMA 4BAAA 4C6GA 1C3CA 1I0AA 5EYVA 4EFCA 1DCNA 1TJUA 2YIIA 3KDZA 4C5RA 1AUWA 1TJWA 3CZOA 4C5UA 2O7FA 4C5SA 3TV2A 1Y2MA 1VDKA 2OHYA 1RE5A 2J91A 3E04A 1YFMA 2RJSA 5EYTA 1GK2A 1Q5NA 1HY0A 3BHGA 4FFXA 1U15A 3NO9A 1YFEA 4NLEA 2O7EA 3R6QA 4HGVA 3NZ4A 4CQ5A 4MX2A 4BABA 4NSLA 1FURA 1FUPA 2X75A 2O78A 3UNVA 5F91A 2NYFA 1T6PA 3OCFA 2VD6A 2O7BA 2PFMA 2QVEA 1K7WA 1T6JA 1XWOA 4V2RA 1TJVA 2PTRA 2QGAB 1FUOA 3QBPA 1YISA 1B8FA 5D6BA
chains in the Genus database with same CATH superfamily
2E9FA 1EB4A 1GKJA 2O6YA 5M0IA 1FUQA 1XL7A 1XMDA 2FUSA 1GKMA 1HY1A 1W27A 2PTSA 3OCEA 4V2QA 3GZHA 1J3UA 2O7DA 2VL7A 1KQ7A 4ADLA 2RJRA 1K62A 5HW2A 1C3UA 3C8TA 4EEIA 1TJ7A 1U16A 3R6YA 3R6VA 4APBA 1JSWA 1DOFA 3RD8A 3RRPA 2PTQA 2NYNA 3KDYA 1GK3A 4FLCA 5F92A 1XL8A 2HVGA 3GTDA 4APAA 4ADMA 4BAAA 4C6GA 1C3CA 1I0AA 5EYVA 4EFCA 1DCNA 1TJUA 2YIIA 3KDZA 4C5RA 1AUWA 1TJWA 3CRVA 3CZOA 4C5UA 5H8WA 2O7FA 4C5SA 4WNLA 3TV2A 2VSFA 5M0JA 1Y2MA 1VDKA 2OHYA 1XLYA 1RE5A 2J91A 3E04A 1YFMA 2RJSA 5EYTA 1GK2A 2FELA 1Q5NA 1HY0A 3BHGA 4FFXA 1U15A 3NO9A 1YFEA 4NLEA 2O7EA 3R6QA 4HGVA 3NZ4A 4CQ5A 4MX2A 4BABA 4NSLA 1FURA 1FUPA 2X75A 2O78A 3UNVA 5F91A 2NYFA 1T6PA 3OCFA 2VD6A 2O7BA 2PFMA 2QVEA 1K7WA 1T6JA 1XWOA 4V2RA 1TJVA 2PTRA 2QGAB 3CRW1 2FENA 1FUOA 3QBPA 1XMCA 1YISA 1B8FA 5D6BA 4A15A
chains in the Genus database with same CATH topology
2E9FA 1EB4A 1GKJA 2O6YA 1FUQA 2FUSA 1GKMA 1HY1A 1W27A 2PTSA 3OCEA 4V2QA 3GZHA 1J3UA 2O7DA 1KQ7A 4ADLA 2RJRA 1K62A 5HW2A 1C3UA 3C8TA 4EEIA 1TJ7A 1U16A 3R6YA 3R6VA 4APBA 1JSWA 1DOFA 3RD8A 3RRPA 2PTQA 2NYNA 3KDYA 1GK3A 4FLCA 5F92A 2HVGA 3GTDA 4APAA 4ADMA 4BAAA 4C6GA 1C3CA 1I0AA 5EYVA 4EFCA 1DCNA 1TJUA 2YIIA 3KDZA 4C5RA 1AUWA 1TJWA 3CZOA 4C5UA 2O7FA 4C5SA 3TV2A 1Y2MA 1VDKA 2OHYA 1RE5A 2J91A 3E04A 1YFMA 2RJSA 5EYTA 1GK2A 1Q5NA 1HY0A 3BHGA 4FFXA 1U15A 3NO9A 1YFEA 4NLEA 2O7EA 3R6QA 4HGVA 3NZ4A 4CQ5A 4MX2A 4BABA 4NSLA 1FURA 1FUPA 2X75A 2O78A 3UNVA 5F91A 2NYFA 1T6PA 3OCFA 2VD6A 2O7BA 2PFMA 2QVEA 1K7WA 1T6JA 1XWOA 4V2RA 1TJVA 2PTRA 2QGAB 1FUOA 3QBPA 1YISA 1B8FA 5D6BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E9F A;  1EB4 A;  1GKJ A;  2O6Y A;  1FUQ A;  2FUS A;  1GKM A;  1HY1 A;  1W27 A;  2PTS A;  3OCE A;  4V2Q A;  3GZH A;  1J3U A;  2O7D A;  1KQ7 A;  4ADL A;  2RJR A;  1K62 A;  5HW2 A;  1C3U A;  3C8T A;  4EEI A;  1TJ7 A;  1U16 A;  3R6Y A;  3R6V A;  4APB A;  1JSW A;  1DOF A;  3RD8 A;  3RRP A;  2PTQ A;  2NYN A;  3KDY A;  1GK3 A;  4FLC A;  5F92 A;  2HVG A;  3GTD A;  4APA A;  4ADM A;  4BAA A;  4C6G A;  1C3C A;  1I0A A;  5EYV A;  4EFC A;  1DCN A;  1TJU A;  2YII A;  3KDZ A;  4C5R A;  1AUW A;  1TJW A;  3CZO A;  4C5U A;  2O7F A;  4C5S A;  3TV2 A;  1Y2M A;  1VDK A;  2OHY A;  1RE5 A;  2J91 A;  3E04 A;  1YFM A;  2RJS A;  5EYT A;  1GK2 A;  1Q5N A;  1HY0 A;  3BHG A;  4FFX A;  1U15 A;  3NO9 A;  1YFE A;  4NLE A;  2O7E A;  3R6Q A;  4HGV A;  3NZ4 A;  4CQ5 A;  4MX2 A;  4BAB A;  4NSL A;  1FUR A;  1FUP A;  2X75 A;  2O78 A;  3UNV A;  5F91 A;  2NYF A;  1T6P A;  3OCF A;  2VD6 A;  2O7B A;  2PFM A;  2QVE A;  1K7W A;  1T6J A;  1XWO A;  4V2R A;  1TJV A;  2PTR A;  2QGA B;  1FUO A;  3QBP A;  1YIS A;  1B8F A;  5D6B A; 
#chains in the Genus database with same CATH topology
 2E9F A;  1EB4 A;  1GKJ A;  2O6Y A;  5M0I A;  1FUQ A;  1XL7 A;  1XMD A;  2FUS A;  1GKM A;  1HY1 A;  1W27 A;  2PTS A;  3OCE A;  4V2Q A;  3GZH A;  1J3U A;  2O7D A;  2VL7 A;  1KQ7 A;  4ADL A;  2RJR A;  1K62 A;  5HW2 A;  1C3U A;  3C8T A;  4EEI A;  1TJ7 A;  1U16 A;  3R6Y A;  3R6V A;  4APB A;  1JSW A;  1DOF A;  3RD8 A;  3RRP A;  2PTQ A;  2NYN A;  3KDY A;  1GK3 A;  4FLC A;  5F92 A;  1XL8 A;  2HVG A;  3GTD A;  4APA A;  4ADM A;  4BAA A;  4C6G A;  1C3C A;  1I0A A;  5EYV A;  4EFC A;  1DCN A;  1TJU A;  2YII A;  3KDZ A;  4C5R A;  1AUW A;  1TJW A;  3CRV A;  3CZO A;  4C5U A;  5H8W A;  2O7F A;  4C5S A;  4WNL A;  3TV2 A;  2VSF A;  5M0J A;  1Y2M A;  1VDK A;  2OHY A;  1XLY A;  1RE5 A;  2J91 A;  3E04 A;  1YFM A;  2RJS A;  5EYT A;  1GK2 A;  2FEL A;  1Q5N A;  1HY0 A;  3BHG A;  4FFX A;  1U15 A;  3NO9 A;  1YFE A;  4NLE A;  2O7E A;  3R6Q A;  4HGV A;  3NZ4 A;  4CQ5 A;  4MX2 A;  4BAB A;  4NSL A;  1FUR A;  1FUP A;  2X75 A;  2O78 A;  3UNV A;  5F91 A;  2NYF A;  1T6P A;  3OCF A;  2VD6 A;  2O7B A;  2PFM A;  2QVE A;  1K7W A;  1T6J A;  1XWO A;  4V2R A;  1TJV A;  2PTR A;  2QGA B;  3CRW 1;  2FEN A;  1FUO A;  3QBP A;  1XMC A;  1YIS A;  1B8F A;  5D6B A;  4A15 A; 
#chains in the Genus database with same CATH homology
 2E9F A;  1EB4 A;  1GKJ A;  2O6Y A;  1FUQ A;  2FUS A;  1GKM A;  1HY1 A;  1W27 A;  2PTS A;  3OCE A;  4V2Q A;  3GZH A;  1J3U A;  2O7D A;  1KQ7 A;  4ADL A;  2RJR A;  1K62 A;  5HW2 A;  1C3U A;  3C8T A;  4EEI A;  1TJ7 A;  1U16 A;  3R6Y A;  3R6V A;  4APB A;  1JSW A;  1DOF A;  3RD8 A;  3RRP A;  2PTQ A;  2NYN A;  3KDY A;  1GK3 A;  4FLC A;  5F92 A;  2HVG A;  3GTD A;  4APA A;  4ADM A;  4BAA A;  4C6G A;  1C3C A;  1I0A A;  5EYV A;  4EFC A;  1DCN A;  1TJU A;  2YII A;  3KDZ A;  4C5R A;  1AUW A;  1TJW A;  3CZO A;  4C5U A;  2O7F A;  4C5S A;  3TV2 A;  1Y2M A;  1VDK A;  2OHY A;  1RE5 A;  2J91 A;  3E04 A;  1YFM A;  2RJS A;  5EYT A;  1GK2 A;  1Q5N A;  1HY0 A;  3BHG A;  4FFX A;  1U15 A;  3NO9 A;  1YFE A;  4NLE A;  2O7E A;  3R6Q A;  4HGV A;  3NZ4 A;  4CQ5 A;  4MX2 A;  4BAB A;  4NSL A;  1FUR A;  1FUP A;  2X75 A;  2O78 A;  3UNV A;  5F91 A;  2NYF A;  1T6P A;  3OCF A;  2VD6 A;  2O7B A;  2PFM A;  2QVE A;  1K7W A;  1T6J A;  1XWO A;  4V2R A;  1TJV A;  2PTR A;  2QGA B;  1FUO A;  3QBP A;  1YIS A;  1B8F A;  5D6B A; 
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