3NO9A

Crystal structure of apo fumarate hydratase from mycobacterium tuberculosis
Total Genus 167
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
167
sequence length
460
structure length
453
Chain Sequence
SANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDLSIEDLDRRLDVLAMAKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis
rcsb
molecule keywords Fumarate hydratase class II
molecule tags Lyase
source organism Mycobacterium tuberculosis
total genus 167
structure length 453
sequence length 460
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2010-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3no9A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3no9A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3no9A02
4C5UA 1XWOA 1GKJA 1J3UA 3BHGA 4HGVA 3KDZA 3OCFA 1U15A 4C6GA 1AUWA 3UNVA 3GZHA 2PTSA 3KDYA 2PTQA 1EB4A 2O78A 1W27A 3GTDA 2X75A 4MX2A 2RJRA 1GK3A 4BABA 2YIIA 2O7FA 1FURA 4C5SA 3E04A 5F91A 2VD6A 4V2RA 1Y2MA 4ADMA 2E9FA 1K62A 1DCNA 1FUQA 1U16A 3OCEA 1GKMA 1HY1A 3NZ4A 1VDKA 2J91A 1TJ7A 3RRPA 1C3UA 1FUPA 2QGAB 2O6YA 4EEIA 4V2QA 3QBPA 1TJUA 3CZOA 2FUSA 3R6VA 2PTRA 1Q5NA 4FLCA 1T6PA 1K7WA 2NYFA 1KQ7A 1T6JA 3RD8A 1HY0A 1FUOA 2HVGA 5HW2A 1I0AA 2O7EA 2RJSA 1DOFA 3C8TA 4C5RA 2PFMA 4BAAA 3TV2A 5F92A 4EFCA 3NO9A 1RE5A 4CQ5A 4NSLA 3R6QA 5D6BA 1GK2A 2OHYA 1TJWA 1TJVA 1YISA 1C3CA 2O7DA 2O7BA 4APAA 4FFXA 5EYVA 4APBA 3R6YA 4NLEA 1B8FA 4ADLA 2NYNA 1JSWA 1YFEA 2QVEA 5EYTA 1YFMA
chains in the Genus database with same CATH superfamily
2RCNA 4C5UA 1MH9A 4L57A 1Q92A 1XWOA 2D27A 1GKJA 1J3UA 3BHGA 2JARA 4HGVA 3KDZA 3OCFA 1U15A 4YIHA 4C6GA 1AUWA 3UNVA 3GZHA 2PTSA 2YV5A 1Z4LA 3F4SA 3KDYA 2PTQA 1EB4A 2O78A 1W27A 3GTDA 2X75A 4MX2A 2RJRA 1Z4QA 1GK3A 4L6CA 1Z4KA 4BABA 4MUMA 4L6AA 4YIKA 2O7FA 2YIIA 1FURA 3CRVA 2I7DA 4C5SA 3CI0K 1Z4PX 3E04A 1XLYA 1U0LA 3CRW1 4MWOA 1XMDA 1Z4MA 5F91A 2VD6A 4V2RA 1Z4IA 2JAOA 1Y2MA 4ADMA 2E9FA 4WNLA 1K62A 2FELA 1DCNA 3F4RA 1XMCA 1FUQA 1U16A 3OCEA 1XL8A 1GKMA 1HY1A 3NZ4A 1VDKA 2D28C 2FENA 2VSFA 2J91A 1TJ7A 3RRPA 1C3UA 1FUPA 2QGAB 2O6YA 4EEIA 1T9HA 2JAWA 4V2QA 4A15A 3QBPA 1TJUA 4NFLA 3CZOA 5M0IA 1XL7A 2FUSA 3R6VA 2PTRA 1Q5NA 4FLCA 1T6PA 1K7WA 2NYFA 1KQ7A 1T6JA 3RD8A 1IW7D 1HY0A 1FUOA 2HVGA 5HW2A 1I0AA 2O7EA 2RJSA 5M0JA 1DOFA 3F4TA 3C8TA 4C5RA 5H8WA 2PFMA 4BAAA 3TV2A 3BWVA 1Z4JA 5F92A 4EFCA 3NO9A 1RE5A 4CQ5A 4NSLA 3R6QA 2VL7A 3U13A 5D6BA 1GK2A 4E88A 2OHYA 1TJWA 1TJVA 2JAUA 1YISA 1C3CA 4IQJM 2O7DA 2O7BA 4APAA 4FFXA 5EYVA 4APBA 3R6YA 4NLEA 3U19A 1B8FA 4ADLA 2NYNA 1JSWA 1YFEA 2QVEA 5EYTA 1YFMA 1Q91A
chains in the Genus database with same CATH topology
4C5UA 1XWOA 1GKJA 1J3UA 3BHGA 4HGVA 3KDZA 3OCFA 1U15A 4C6GA 1AUWA 3UNVA 3GZHA 2PTSA 3KDYA 2PTQA 1EB4A 2O78A 1W27A 3GTDA 2X75A 4MX2A 2RJRA 1GK3A 4BABA 2YIIA 2O7FA 1FURA 4C5SA 3E04A 5F91A 2VD6A 4V2RA 1Y2MA 4ADMA 2E9FA 1K62A 1DCNA 1FUQA 1U16A 3OCEA 1GKMA 1HY1A 3NZ4A 1VDKA 2J91A 1TJ7A 3RRPA 1C3UA 1FUPA 2QGAB 2O6YA 4EEIA 4V2QA 3QBPA 1TJUA 3CZOA 2FUSA 3R6VA 2PTRA 1Q5NA 4FLCA 1T6PA 1K7WA 2NYFA 1KQ7A 1T6JA 3RD8A 1HY0A 1FUOA 2HVGA 5HW2A 1I0AA 2O7EA 2RJSA 1DOFA 3C8TA 4C5RA 2PFMA 4BAAA 3TV2A 5F92A 4EFCA 3NO9A 1RE5A 4CQ5A 4NSLA 3R6QA 5D6BA 1GK2A 2OHYA 1TJWA 1TJVA 1YISA 1C3CA 2O7DA 2O7BA 4APAA 4FFXA 5EYVA 4APBA 3R6YA 4NLEA 1B8FA 4ADLA 2NYNA 1JSWA 1YFEA 2QVEA 5EYTA 1YFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5U A;  1XWO A;  1GKJ A;  1J3U A;  3BHG A;  4HGV A;  3KDZ A;  3OCF A;  1U15 A;  4C6G A;  1AUW A;  3UNV A;  3GZH A;  2PTS A;  3KDY A;  2PTQ A;  1EB4 A;  2O78 A;  1W27 A;  3GTD A;  2X75 A;  4MX2 A;  2RJR A;  1GK3 A;  4BAB A;  2YII A;  2O7F A;  1FUR A;  4C5S A;  3E04 A;  5F91 A;  2VD6 A;  4V2R A;  1Y2M A;  4ADM A;  2E9F A;  1K62 A;  1DCN A;  1FUQ A;  1U16 A;  3OCE A;  1GKM A;  1HY1 A;  3NZ4 A;  1VDK A;  2J91 A;  1TJ7 A;  3RRP A;  1C3U A;  1FUP A;  2QGA B;  2O6Y A;  4EEI A;  4V2Q A;  3QBP A;  1TJU A;  3CZO A;  2FUS A;  3R6V A;  2PTR A;  1Q5N A;  4FLC A;  1T6P A;  1K7W A;  2NYF A;  1KQ7 A;  1T6J A;  3RD8 A;  1HY0 A;  1FUO A;  2HVG A;  5HW2 A;  1I0A A;  2O7E A;  2RJS A;  1DOF A;  3C8T A;  4C5R A;  2PFM A;  4BAA A;  3TV2 A;  5F92 A;  4EFC A;  3NO9 A;  1RE5 A;  4CQ5 A;  4NSL A;  3R6Q A;  5D6B A;  1GK2 A;  2OHY A;  1TJW A;  1TJV A;  1YIS A;  1C3C A;  2O7D A;  2O7B A;  4APA A;  4FFX A;  5EYV A;  4APB A;  3R6Y A;  4NLE A;  1B8F A;  4ADL A;  2NYN A;  1JSW A;  1YFE A;  2QVE A;  5EYT A;  1YFM A; 
#chains in the Genus database with same CATH topology
 2RCN A;  4C5U A;  1MH9 A;  4L57 A;  1Q92 A;  1XWO A;  2D27 A;  1GKJ A;  1J3U A;  3BHG A;  2JAR A;  4HGV A;  3KDZ A;  3OCF A;  1U15 A;  4YIH A;  4C6G A;  1AUW A;  3UNV A;  3GZH A;  2PTS A;  2YV5 A;  1Z4L A;  3F4S A;  3KDY A;  2PTQ A;  1EB4 A;  2O78 A;  1W27 A;  3GTD A;  2X75 A;  4MX2 A;  2RJR A;  1Z4Q A;  1GK3 A;  4L6C A;  1Z4K A;  4BAB A;  4MUM A;  4L6A A;  4YIK A;  2O7F A;  2YII A;  1FUR A;  3CRV A;  2I7D A;  4C5S A;  3CI0 K;  1Z4P X;  3E04 A;  1XLY A;  1U0L A;  3CRW 1;  4MWO A;  1XMD A;  1Z4M A;  5F91 A;  2VD6 A;  4V2R A;  1Z4I A;  2JAO A;  1Y2M A;  4ADM A;  2E9F A;  4WNL A;  1K62 A;  2FEL A;  1DCN A;  3F4R A;  1XMC A;  1FUQ A;  1U16 A;  3OCE A;  1XL8 A;  1GKM A;  1HY1 A;  3NZ4 A;  1VDK A;  2D28 C;  2FEN A;  2VSF A;  2J91 A;  1TJ7 A;  3RRP A;  1C3U A;  1FUP A;  2QGA B;  2O6Y A;  4EEI A;  1T9H A;  2JAW A;  4V2Q A;  4A15 A;  3QBP A;  1TJU A;  4NFL A;  3CZO A;  5M0I A;  1XL7 A;  2FUS A;  3R6V A;  2PTR A;  1Q5N A;  4FLC A;  1T6P A;  1K7W A;  2NYF A;  1KQ7 A;  1T6J A;  3RD8 A;  1IW7 D;  1HY0 A;  1FUO A;  2HVG A;  5HW2 A;  1I0A A;  2O7E A;  2RJS A;  5M0J A;  1DOF A;  3F4T A;  3C8T A;  4C5R A;  5H8W A;  2PFM A;  4BAA A;  3TV2 A;  3BWV A;  1Z4J A;  5F92 A;  4EFC A;  3NO9 A;  1RE5 A;  4CQ5 A;  4NSL A;  3R6Q A;  2VL7 A;  3U13 A;  5D6B A;  1GK2 A;  4E88 A;  2OHY A;  1TJW A;  1TJV A;  2JAU A;  1YIS A;  1C3C A;  4IQJ M;  2O7D A;  2O7B A;  4APA A;  4FFX A;  5EYV A;  4APB A;  3R6Y A;  4NLE A;  3U19 A;  1B8F A;  4ADL A;  2NYN A;  1JSW A;  1YFE A;  2QVE A;  5EYT A;  1YFM A;  1Q91 A; 
#chains in the Genus database with same CATH homology
 4C5U A;  1XWO A;  1GKJ A;  1J3U A;  3BHG A;  4HGV A;  3KDZ A;  3OCF A;  1U15 A;  4C6G A;  1AUW A;  3UNV A;  3GZH A;  2PTS A;  3KDY A;  2PTQ A;  1EB4 A;  2O78 A;  1W27 A;  3GTD A;  2X75 A;  4MX2 A;  2RJR A;  1GK3 A;  4BAB A;  2YII A;  2O7F A;  1FUR A;  4C5S A;  3E04 A;  5F91 A;  2VD6 A;  4V2R A;  1Y2M A;  4ADM A;  2E9F A;  1K62 A;  1DCN A;  1FUQ A;  1U16 A;  3OCE A;  1GKM A;  1HY1 A;  3NZ4 A;  1VDK A;  2J91 A;  1TJ7 A;  3RRP A;  1C3U A;  1FUP A;  2QGA B;  2O6Y A;  4EEI A;  4V2Q A;  3QBP A;  1TJU A;  3CZO A;  2FUS A;  3R6V A;  2PTR A;  1Q5N A;  4FLC A;  1T6P A;  1K7W A;  2NYF A;  1KQ7 A;  1T6J A;  3RD8 A;  1HY0 A;  1FUO A;  2HVG A;  5HW2 A;  1I0A A;  2O7E A;  2RJS A;  1DOF A;  3C8T A;  4C5R A;  2PFM A;  4BAA A;  3TV2 A;  5F92 A;  4EFC A;  3NO9 A;  1RE5 A;  4CQ5 A;  4NSL A;  3R6Q A;  5D6B A;  1GK2 A;  2OHY A;  1TJW A;  1TJV A;  1YIS A;  1C3C A;  2O7D A;  2O7B A;  4APA A;  4FFX A;  5EYV A;  4APB A;  3R6Y A;  4NLE A;  1B8F A;  4ADL A;  2NYN A;  1JSW A;  1YFE A;  2QVE A;  5EYT A;  1YFM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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