3NO9A

Crystal structure of apo fumarate hydratase from mycobacterium tuberculosis
Total Genus 167
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
167
sequence length
460
structure length
453
Chain Sequence
b'SANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDLSIEDLDRRLDVLAMAKA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis
rcsb
molecule keywords Fumarate hydratase class II
source organism Mycobacterium tuberculosis
molecule tags Lyase
total genus 167
structure length 453
sequence length 460
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2010-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3no9A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3no9A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3no9A02
1KQ7A 1TJVA 3NZ4A 3KDYA 1YISA 4BAAA 5HW2A 1TJWA 3UNVA 1C3UA 1GKJA 2RJRA 4FLCA 2O7FA 1DCNA 1HY0A 1U15A 5D6BA 1AUWA 5EYTA 4APBA 4BABA 1I0AA 4FFXA 1RE5A 1XWOA 4V2QA 4EEIA 4C6GA 2PTRA 1C3CA 3BHGA 3R6VA 4NLEA 2VD6A 2QVEA 1YFMA 1HY1A 2PTQA 3CZOA 4CQ5A 4ADMA 3GTDA 2HVGA 4NSLA 2O7BA 2X75A 5F92A 4V2RA 1TJ7A 3E04A 2PFMA 1Q5NA 1VDKA 3RRPA 2J91A 4C5RA 1FURA 5EYVA 1T6JA 1B8FA 3TV2A 1GK2A 1J3UA 3R6YA 1GK3A 3KDZA 1W27A 3R6QA 2NYNA 2O7DA 1EB4A 2O78A 1GKMA 2RJSA 1K62A 1T6PA 2YIIA 4C5SA 3OCFA 1YFEA 1FUPA 2OHYA 3NO9A 2FUSA 2NYFA 4ADLA 2PTSA 2E9FA 3C8TA 4MX2A 1K7WA 1TJUA 3OCEA 5F91A 4APAA 1JSWA 2O7EA 2O6YA 3RD8A 1Y2MA 4HGVA 1U16A 4EFCA 2QGAB 1FUOA 3QBPA 4C5UA 1FUQA 3GZHA 1DOFA
chains in the Genus database with same CATH superfamily
1KQ7A 1TJVA 3NZ4A 3F4SA 3KDYA 1YISA 4BAAA 5HW2A 1TJWA 3UNVA 1C3UA 1GKJA 2RJRA 4FLCA 2O7FA 1Q91A 4IQJM 1DCNA 5M0JA 1HY0A 1U15A 4L6CA 5D6BA 3U13A 1T9HA 1AUWA 5EYTA 4APBA 4BABA 1I0AA 4FFXA 4NFLA 1RE5A 1XWOA 1Z4QA 3CRVA 4V2QA 4EEIA 1XLYA 5M0IA 4C6GA 1IW7D 2PTRA 3CRW1 1C3CA 3BHGA 3R6VA 3CI0K 4NLEA 2VD6A 3F4TA 1XMCA 2QVEA 1YFMA 1HY1A 2PTQA 3CZOA 2JARA 4ADMA 4CQ5A 3GTDA 2HVGA 4NSLA 2O7BA 2X75A 5F92A 4V2RA 1TJ7A 3E04A 1XL8A 1Z4JA 2RCNA 2PFMA 1Q5NA 1VDKA 4MWOA 3RRPA 2J91A 2FELA 2I7DA 2D28C 1FURA 4C5RA 2JAWA 5EYVA 1T6JA 1B8FA 3TV2A 1GK2A 1J3UA 3R6YA 1GK3A 2JAOA 5H8WA 3KDZA 1W27A 3R6QA 2NYNA 2O7DA 2VL7A 1EB4A 2O78A 4MUMA 1Z4PX 1GKMA 2VSFA 1MH9A 2D27A 1XMDA 2RJSA 1K62A 3F4RA 1T6PA 1Z4IA 2YIIA 2YV5A 4C5SA 3BWVA 3OCFA 1YFEA 1FUPA 2OHYA 4A15A 4WNLA 3NO9A 2FUSA 4YIHA 2NYFA 1Q92A 4ADLA 1Z4KA 2PTSA 2E9FA 3C8TA 1Z4LA 1U0LA 4MX2A 1K7WA 1TJUA 3OCEA 1XL7A 1Z4MA 5F91A 4APAA 1JSWA 2O7EA 2O6YA 3RD8A 4E88A 1Y2MA 4L6AA 2FENA 2JAUA 4HGVA 1U16A 4EFCA 2QGAB 1FUOA 3QBPA 4C5UA 4YIKA 1FUQA 3GZHA 1DOFA 4L57A 3U19A
chains in the Genus database with same CATH topology
1KQ7A 1TJVA 3NZ4A 3KDYA 1YISA 4BAAA 5HW2A 1TJWA 3UNVA 1C3UA 1GKJA 2RJRA 4FLCA 2O7FA 1DCNA 1HY0A 1U15A 5D6BA 1AUWA 5EYTA 4APBA 4BABA 1I0AA 4FFXA 1RE5A 1XWOA 4V2QA 4EEIA 4C6GA 2PTRA 1C3CA 3BHGA 3R6VA 4NLEA 2VD6A 2QVEA 1YFMA 1HY1A 2PTQA 3CZOA 4CQ5A 4ADMA 3GTDA 2HVGA 4NSLA 2O7BA 2X75A 5F92A 4V2RA 1TJ7A 3E04A 2PFMA 1Q5NA 1VDKA 3RRPA 2J91A 4C5RA 1FURA 5EYVA 1T6JA 1B8FA 3TV2A 1GK2A 1J3UA 3R6YA 1GK3A 3KDZA 1W27A 3R6QA 2NYNA 2O7DA 1EB4A 2O78A 1GKMA 2RJSA 1K62A 1T6PA 2YIIA 4C5SA 3OCFA 1YFEA 1FUPA 2OHYA 3NO9A 2FUSA 2NYFA 4ADLA 2PTSA 2E9FA 3C8TA 4MX2A 1K7WA 1TJUA 3OCEA 5F91A 4APAA 1JSWA 2O7EA 2O6YA 3RD8A 1Y2MA 4HGVA 1U16A 4EFCA 2QGAB 1FUOA 3QBPA 4C5UA 1FUQA 3GZHA 1DOFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KQ7 A;  1TJV A;  3NZ4 A;  3KDY A;  1YIS A;  4BAA A;  5HW2 A;  1TJW A;  3UNV A;  1C3U A;  1GKJ A;  2RJR A;  4FLC A;  2O7F A;  1DCN A;  1HY0 A;  1U15 A;  5D6B A;  1AUW A;  5EYT A;  4APB A;  4BAB A;  1I0A A;  4FFX A;  1RE5 A;  1XWO A;  4V2Q A;  4EEI A;  4C6G A;  2PTR A;  1C3C A;  3BHG A;  3R6V A;  4NLE A;  2VD6 A;  2QVE A;  1YFM A;  1HY1 A;  2PTQ A;  3CZO A;  4CQ5 A;  4ADM A;  3GTD A;  2HVG A;  4NSL A;  2O7B A;  2X75 A;  5F92 A;  4V2R A;  1TJ7 A;  3E04 A;  2PFM A;  1Q5N A;  1VDK A;  3RRP A;  2J91 A;  4C5R A;  1FUR A;  5EYV A;  1T6J A;  1B8F A;  3TV2 A;  1GK2 A;  1J3U A;  3R6Y A;  1GK3 A;  3KDZ A;  1W27 A;  3R6Q A;  2NYN A;  2O7D A;  1EB4 A;  2O78 A;  1GKM A;  2RJS A;  1K62 A;  1T6P A;  2YII A;  4C5S A;  3OCF A;  1YFE A;  1FUP A;  2OHY A;  3NO9 A;  2FUS A;  2NYF A;  4ADL A;  2PTS A;  2E9F A;  3C8T A;  4MX2 A;  1K7W A;  1TJU A;  3OCE A;  5F91 A;  4APA A;  1JSW A;  2O7E A;  2O6Y A;  3RD8 A;  1Y2M A;  4HGV A;  1U16 A;  4EFC A;  2QGA B;  1FUO A;  3QBP A;  4C5U A;  1FUQ A;  3GZH A;  1DOF A; 
#chains in the Genus database with same CATH topology
 1KQ7 A;  1TJV A;  3NZ4 A;  3F4S A;  3KDY A;  1YIS A;  4BAA A;  5HW2 A;  1TJW A;  3UNV A;  1C3U A;  1GKJ A;  2RJR A;  4FLC A;  2O7F A;  1Q91 A;  4IQJ M;  1DCN A;  5M0J A;  1HY0 A;  1U15 A;  4L6C A;  5D6B A;  3U13 A;  1T9H A;  1AUW A;  5EYT A;  4APB A;  4BAB A;  1I0A A;  4FFX A;  4NFL A;  1RE5 A;  1XWO A;  1Z4Q A;  3CRV A;  4V2Q A;  4EEI A;  1XLY A;  5M0I A;  4C6G A;  1IW7 D;  2PTR A;  3CRW 1;  1C3C A;  3BHG A;  3R6V A;  3CI0 K;  4NLE A;  2VD6 A;  3F4T A;  1XMC A;  2QVE A;  1YFM A;  1HY1 A;  2PTQ A;  3CZO A;  2JAR A;  4ADM A;  4CQ5 A;  3GTD A;  2HVG A;  4NSL A;  2O7B A;  2X75 A;  5F92 A;  4V2R A;  1TJ7 A;  3E04 A;  1XL8 A;  1Z4J A;  2RCN A;  2PFM A;  1Q5N A;  1VDK A;  4MWO A;  3RRP A;  2J91 A;  2FEL A;  2I7D A;  2D28 C;  1FUR A;  4C5R A;  2JAW A;  5EYV A;  1T6J A;  1B8F A;  3TV2 A;  1GK2 A;  1J3U A;  3R6Y A;  1GK3 A;  2JAO A;  5H8W A;  3KDZ A;  1W27 A;  3R6Q A;  2NYN A;  2O7D A;  2VL7 A;  1EB4 A;  2O78 A;  4MUM A;  1Z4P X;  1GKM A;  2VSF A;  1MH9 A;  2D27 A;  1XMD A;  2RJS A;  1K62 A;  3F4R A;  1T6P A;  1Z4I A;  2YII A;  2YV5 A;  4C5S A;  3BWV A;  3OCF A;  1YFE A;  1FUP A;  2OHY A;  4A15 A;  4WNL A;  3NO9 A;  2FUS A;  4YIH A;  2NYF A;  1Q92 A;  4ADL A;  1Z4K A;  2PTS A;  2E9F A;  3C8T A;  1Z4L A;  1U0L A;  4MX2 A;  1K7W A;  1TJU A;  3OCE A;  1XL7 A;  1Z4M A;  5F91 A;  4APA A;  1JSW A;  2O7E A;  2O6Y A;  3RD8 A;  4E88 A;  1Y2M A;  4L6A A;  2FEN A;  2JAU A;  4HGV A;  1U16 A;  4EFC A;  2QGA B;  1FUO A;  3QBP A;  4C5U A;  4YIK A;  1FUQ A;  3GZH A;  1DOF A;  4L57 A;  3U19 A; 
#chains in the Genus database with same CATH homology
 1KQ7 A;  1TJV A;  3NZ4 A;  3KDY A;  1YIS A;  4BAA A;  5HW2 A;  1TJW A;  3UNV A;  1C3U A;  1GKJ A;  2RJR A;  4FLC A;  2O7F A;  1DCN A;  1HY0 A;  1U15 A;  5D6B A;  1AUW A;  5EYT A;  4APB A;  4BAB A;  1I0A A;  4FFX A;  1RE5 A;  1XWO A;  4V2Q A;  4EEI A;  4C6G A;  2PTR A;  1C3C A;  3BHG A;  3R6V A;  4NLE A;  2VD6 A;  2QVE A;  1YFM A;  1HY1 A;  2PTQ A;  3CZO A;  4CQ5 A;  4ADM A;  3GTD A;  2HVG A;  4NSL A;  2O7B A;  2X75 A;  5F92 A;  4V2R A;  1TJ7 A;  3E04 A;  2PFM A;  1Q5N A;  1VDK A;  3RRP A;  2J91 A;  4C5R A;  1FUR A;  5EYV A;  1T6J A;  1B8F A;  3TV2 A;  1GK2 A;  1J3U A;  3R6Y A;  1GK3 A;  3KDZ A;  1W27 A;  3R6Q A;  2NYN A;  2O7D A;  1EB4 A;  2O78 A;  1GKM A;  2RJS A;  1K62 A;  1T6P A;  2YII A;  4C5S A;  3OCF A;  1YFE A;  1FUP A;  2OHY A;  3NO9 A;  2FUS A;  2NYF A;  4ADL A;  2PTS A;  2E9F A;  3C8T A;  4MX2 A;  1K7W A;  1TJU A;  3OCE A;  5F91 A;  4APA A;  1JSW A;  2O7E A;  2O6Y A;  3RD8 A;  1Y2M A;  4HGV A;  1U16 A;  4EFC A;  2QGA B;  1FUO A;  3QBP A;  4C5U A;  1FUQ A;  3GZH A;  1DOF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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