3NO9A

Crystal structure of apo fumarate hydratase from mycobacterium tuberculosis
Total Genus 167
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
167
sequence length
460
structure length
453
Chain Sequence
SANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDLSIEDLDRRLDVLAMAKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis
rcsb
source organism Mycobacterium tuberculosis
molecule tags Lyase
molecule keywords Fumarate hydratase class II
total genus 167
structure length 453
sequence length 460
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2010-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3no9A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3no9A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3no9A02
1RE5A 3TV2A 5F92A 3C8TA 2O6YA 1T6JA 4EFCA 3CZOA 1FUOA 4C6GA 2NYFA 4CQ5A 1C3UA 3BHGA 3NZ4A 1YISA 2X75A 1W27A 1GKJA 4BABA 3KDZA 3GZHA 2O7FA 3E04A 5F91A 1FURA 1DOFA 2E9FA 4ADLA 1EB4A 1KQ7A 1GK2A 1JSWA 2O7EA 1J3UA 1K7WA 4HGVA 1T6PA 3RRPA 1C3CA 2QGAB 4APAA 1Y2MA 2QVEA 2RJSA 3R6VA 3KDYA 2OHYA 2RJRA 2YIIA 5EYVA 1K62A 5HW2A 1Q5NA 2FUSA 4C5RA 4ADMA 1TJWA 4EEIA 1FUQA 2PTRA 1TJUA 1TJ7A 2O7DA 3OCEA 1GK3A 2PFMA 1FUPA 2O7BA 2HVGA 2J91A 4BAAA 1VDKA 1U15A 4MX2A 1HY0A 1XWOA 3UNVA 3OCFA 3R6QA 2VD6A 4NSLA 1I0AA 4V2RA 4NLEA 5EYTA 1HY1A 1AUWA 1YFEA 4FLCA 3RD8A 2PTSA 2PTQA 1GKMA 3QBPA 4FFXA 5D6BA 4C5UA 2NYNA 1TJVA 1YFMA 4V2QA 1B8FA 1U16A 3NO9A 2O78A 3GTDA 1DCNA 3R6YA 4C5SA 4APBA
chains in the Genus database with same CATH superfamily
1RE5A 3TV2A 1Q92A 1MH9A 5F92A 1T9HA 4MWOA 3C8TA 4L6CA 2O6YA 1T6JA 4EFCA 3CZOA 2YV5A 2D28C 1FUOA 1XL7A 4C6GA 2NYFA 4CQ5A 1C3UA 3BHGA 3NZ4A 1YISA 2X75A 3U13A 2D27A 1W27A 5H8WA 1GKJA 4BABA 5M0IA 4NFLA 1XL8A 3KDZA 3GZHA 2O7FA 1IW7D 3E04A 5F91A 2VSFA 1FURA 1DOFA 2E9FA 1Q91A 4ADLA 1EB4A 1KQ7A 3CI0K 4A15A 1Z4PX 1GK2A 1JSWA 2FENA 2O7EA 5M0JA 1J3UA 1K7WA 4HGVA 1Z4JA 1T6PA 3RRPA 3CRW1 1C3CA 2QGAB 4APAA 1Y2MA 2QVEA 2RJSA 3R6VA 3KDYA 2OHYA 2RJRA 2YIIA 5EYVA 1XMDA 1K62A 5HW2A 1Q5NA 2FUSA 4C5RA 4ADMA 2RCNA 2JARA 1TJWA 4IQJM 4L6AA 3CRVA 4L57A 4E88A 4WNLA 4EEIA 1FUQA 2PTRA 1TJUA 4YIHA 2FELA 1TJ7A 4MUMA 2O7DA 3OCEA 1GK3A 2PFMA 3F4SA 1FUPA 2O7BA 1Z4QA 1Z4MA 1Z4IA 1XLYA 2HVGA 2J91A 4BAAA 1VDKA 1U15A 3U19A 4MX2A 1HY0A 4YIKA 1XWOA 3UNVA 2JAOA 3OCFA 3R6QA 1U0LA 2VD6A 1Z4KA 4NSLA 1XMCA 2VL7A 1I0AA 4V2RA 3F4RA 3F4TA 4NLEA 5EYTA 1HY1A 1AUWA 1YFEA 1Z4LA 4FLCA 3RD8A 2PTSA 2PTQA 2JAUA 1GKMA 3QBPA 4FFXA 5D6BA 4C5UA 2NYNA 3BWVA 1TJVA 2JAWA 1YFMA 4V2QA 1B8FA 1U16A 3NO9A 2I7DA 2O78A 3GTDA 1DCNA 3R6YA 4C5SA 4APBA
chains in the Genus database with same CATH topology
1RE5A 3TV2A 5F92A 3C8TA 2O6YA 1T6JA 4EFCA 3CZOA 1FUOA 4C6GA 2NYFA 4CQ5A 1C3UA 3BHGA 3NZ4A 1YISA 2X75A 1W27A 1GKJA 4BABA 3KDZA 3GZHA 2O7FA 3E04A 5F91A 1FURA 1DOFA 2E9FA 4ADLA 1EB4A 1KQ7A 1GK2A 1JSWA 2O7EA 1J3UA 1K7WA 4HGVA 1T6PA 3RRPA 1C3CA 2QGAB 4APAA 1Y2MA 2QVEA 2RJSA 3R6VA 3KDYA 2OHYA 2RJRA 2YIIA 5EYVA 1K62A 5HW2A 1Q5NA 2FUSA 4C5RA 4ADMA 1TJWA 4EEIA 1FUQA 2PTRA 1TJUA 1TJ7A 2O7DA 3OCEA 1GK3A 2PFMA 1FUPA 2O7BA 2HVGA 2J91A 4BAAA 1VDKA 1U15A 4MX2A 1HY0A 1XWOA 3UNVA 3OCFA 3R6QA 2VD6A 4NSLA 1I0AA 4V2RA 4NLEA 5EYTA 1HY1A 1AUWA 1YFEA 4FLCA 3RD8A 2PTSA 2PTQA 1GKMA 3QBPA 4FFXA 5D6BA 4C5UA 2NYNA 1TJVA 1YFMA 4V2QA 1B8FA 1U16A 3NO9A 2O78A 3GTDA 1DCNA 3R6YA 4C5SA 4APBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RE5 A;  3TV2 A;  5F92 A;  3C8T A;  2O6Y A;  1T6J A;  4EFC A;  3CZO A;  1FUO A;  4C6G A;  2NYF A;  4CQ5 A;  1C3U A;  3BHG A;  3NZ4 A;  1YIS A;  2X75 A;  1W27 A;  1GKJ A;  4BAB A;  3KDZ A;  3GZH A;  2O7F A;  3E04 A;  5F91 A;  1FUR A;  1DOF A;  2E9F A;  4ADL A;  1EB4 A;  1KQ7 A;  1GK2 A;  1JSW A;  2O7E A;  1J3U A;  1K7W A;  4HGV A;  1T6P A;  3RRP A;  1C3C A;  2QGA B;  4APA A;  1Y2M A;  2QVE A;  2RJS A;  3R6V A;  3KDY A;  2OHY A;  2RJR A;  2YII A;  5EYV A;  1K62 A;  5HW2 A;  1Q5N A;  2FUS A;  4C5R A;  4ADM A;  1TJW A;  4EEI A;  1FUQ A;  2PTR A;  1TJU A;  1TJ7 A;  2O7D A;  3OCE A;  1GK3 A;  2PFM A;  1FUP A;  2O7B A;  2HVG A;  2J91 A;  4BAA A;  1VDK A;  1U15 A;  4MX2 A;  1HY0 A;  1XWO A;  3UNV A;  3OCF A;  3R6Q A;  2VD6 A;  4NSL A;  1I0A A;  4V2R A;  4NLE A;  5EYT A;  1HY1 A;  1AUW A;  1YFE A;  4FLC A;  3RD8 A;  2PTS A;  2PTQ A;  1GKM A;  3QBP A;  4FFX A;  5D6B A;  4C5U A;  2NYN A;  1TJV A;  1YFM A;  4V2Q A;  1B8F A;  1U16 A;  3NO9 A;  2O78 A;  3GTD A;  1DCN A;  3R6Y A;  4C5S A;  4APB A; 
#chains in the Genus database with same CATH topology
 1RE5 A;  3TV2 A;  1Q92 A;  1MH9 A;  5F92 A;  1T9H A;  4MWO A;  3C8T A;  4L6C A;  2O6Y A;  1T6J A;  4EFC A;  3CZO A;  2YV5 A;  2D28 C;  1FUO A;  1XL7 A;  4C6G A;  2NYF A;  4CQ5 A;  1C3U A;  3BHG A;  3NZ4 A;  1YIS A;  2X75 A;  3U13 A;  2D27 A;  1W27 A;  5H8W A;  1GKJ A;  4BAB A;  5M0I A;  4NFL A;  1XL8 A;  3KDZ A;  3GZH A;  2O7F A;  1IW7 D;  3E04 A;  5F91 A;  2VSF A;  1FUR A;  1DOF A;  2E9F A;  1Q91 A;  4ADL A;  1EB4 A;  1KQ7 A;  3CI0 K;  4A15 A;  1Z4P X;  1GK2 A;  1JSW A;  2FEN A;  2O7E A;  5M0J A;  1J3U A;  1K7W A;  4HGV A;  1Z4J A;  1T6P A;  3RRP A;  3CRW 1;  1C3C A;  2QGA B;  4APA A;  1Y2M A;  2QVE A;  2RJS A;  3R6V A;  3KDY A;  2OHY A;  2RJR A;  2YII A;  5EYV A;  1XMD A;  1K62 A;  5HW2 A;  1Q5N A;  2FUS A;  4C5R A;  4ADM A;  2RCN A;  2JAR A;  1TJW A;  4IQJ M;  4L6A A;  3CRV A;  4L57 A;  4E88 A;  4WNL A;  4EEI A;  1FUQ A;  2PTR A;  1TJU A;  4YIH A;  2FEL A;  1TJ7 A;  4MUM A;  2O7D A;  3OCE A;  1GK3 A;  2PFM A;  3F4S A;  1FUP A;  2O7B A;  1Z4Q A;  1Z4M A;  1Z4I A;  1XLY A;  2HVG A;  2J91 A;  4BAA A;  1VDK A;  1U15 A;  3U19 A;  4MX2 A;  1HY0 A;  4YIK A;  1XWO A;  3UNV A;  2JAO A;  3OCF A;  3R6Q A;  1U0L A;  2VD6 A;  1Z4K A;  4NSL A;  1XMC A;  2VL7 A;  1I0A A;  4V2R A;  3F4R A;  3F4T A;  4NLE A;  5EYT A;  1HY1 A;  1AUW A;  1YFE A;  1Z4L A;  4FLC A;  3RD8 A;  2PTS A;  2PTQ A;  2JAU A;  1GKM A;  3QBP A;  4FFX A;  5D6B A;  4C5U A;  2NYN A;  3BWV A;  1TJV A;  2JAW A;  1YFM A;  4V2Q A;  1B8F A;  1U16 A;  3NO9 A;  2I7D A;  2O78 A;  3GTD A;  1DCN A;  3R6Y A;  4C5S A;  4APB A; 
#chains in the Genus database with same CATH homology
 1RE5 A;  3TV2 A;  5F92 A;  3C8T A;  2O6Y A;  1T6J A;  4EFC A;  3CZO A;  1FUO A;  4C6G A;  2NYF A;  4CQ5 A;  1C3U A;  3BHG A;  3NZ4 A;  1YIS A;  2X75 A;  1W27 A;  1GKJ A;  4BAB A;  3KDZ A;  3GZH A;  2O7F A;  3E04 A;  5F91 A;  1FUR A;  1DOF A;  2E9F A;  4ADL A;  1EB4 A;  1KQ7 A;  1GK2 A;  1JSW A;  2O7E A;  1J3U A;  1K7W A;  4HGV A;  1T6P A;  3RRP A;  1C3C A;  2QGA B;  4APA A;  1Y2M A;  2QVE A;  2RJS A;  3R6V A;  3KDY A;  2OHY A;  2RJR A;  2YII A;  5EYV A;  1K62 A;  5HW2 A;  1Q5N A;  2FUS A;  4C5R A;  4ADM A;  1TJW A;  4EEI A;  1FUQ A;  2PTR A;  1TJU A;  1TJ7 A;  2O7D A;  3OCE A;  1GK3 A;  2PFM A;  1FUP A;  2O7B A;  2HVG A;  2J91 A;  4BAA A;  1VDK A;  1U15 A;  4MX2 A;  1HY0 A;  1XWO A;  3UNV A;  3OCF A;  3R6Q A;  2VD6 A;  4NSL A;  1I0A A;  4V2R A;  4NLE A;  5EYT A;  1HY1 A;  1AUW A;  1YFE A;  4FLC A;  3RD8 A;  2PTS A;  2PTQ A;  1GKM A;  3QBP A;  4FFX A;  5D6B A;  4C5U A;  2NYN A;  1TJV A;  1YFM A;  4V2Q A;  1B8F A;  1U16 A;  3NO9 A;  2O78 A;  3GTD A;  1DCN A;  3R6Y A;  4C5S A;  4APB A; 
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similar chains in the pdb database (?% sequence similarity)

 
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