3NO9A

Crystal structure of apo fumarate hydratase from mycobacterium tuberculosis
Total Genus 167
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
167
sequence length
460
structure length
453
Chain Sequence
SANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDLSIEDLDRRLDVLAMAKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Fumarate hydratase class II
publication title Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis
rcsb
source organism Mycobacterium tuberculosis
molecule tags Lyase
total genus 167
structure length 453
sequence length 460
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2010-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3no9A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3no9A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3no9A02
1Y2MA 3R6YA 4FFXA 1FUPA 1GKMA 1HY0A 1K7WA 3NZ4A 3OCFA 2O78A 3OCEA 2VD6A 1U16A 2NYNA 5D6BA 2O7BA 1I0AA 1TJ7A 2RJRA 2OHYA 4NSLA 1DCNA 4C5SA 1EB4A 3KDYA 1C3CA 1Q5NA 1TJVA 1VDKA 1FURA 1YFEA 5HW2A 4HGVA 5EYVA 2PTSA 1KQ7A 1GK2A 1RE5A 2PFMA 4ADMA 1W27A 2O7EA 4C5RA 1U15A 4MX2A 3RD8A 4ADLA 4C5UA 1FUOA 2PTQA 3E04A 3QBPA 4BAAA 4V2RA 1XWOA 1B8FA 2QVEA 4CQ5A 4BABA 3RRPA 1K62A 3TV2A 1AUWA 2YIIA 2O6YA 3C8TA 4V2QA 4NLEA 2NYFA 3CZOA 1YFMA 2O7DA 1DOFA 4EFCA 4FLCA 3R6QA 1HY1A 1T6PA 1FUQA 3R6VA 5F92A 2X75A 4EEIA 1C3UA 3GTDA 1JSWA 4APAA 2QGAB 2E9FA 4APBA 5EYTA 2FUSA 1J3UA 2HVGA 2RJSA 1TJWA 1YISA 1T6JA 4C6GA 1TJUA 1GKJA 3KDZA 3UNVA 3NO9A 3GZHA 2J91A 2O7FA 2PTRA 3BHGA 5F91A 1GK3A
chains in the Genus database with same CATH superfamily
1Y2MA 3R6YA 2D28C 4FFXA 4A15A 1FUPA 1GKMA 1HY0A 1K7WA 1XMDA 3NZ4A 3OCFA 3U13A 2D27A 3F4RA 2I7DA 2O78A 3OCEA 2VD6A 1U16A 3F4TA 5D6BA 2NYNA 2O7BA 1I0AA 1Z4MA 1TJ7A 2RJRA 2OHYA 4NSLA 1DCNA 4C5SA 1EB4A 3KDYA 3CRW1 2VSFA 1C3CA 1Q5NA 4E88A 1Q92A 4IQJM 2YV5A 1TJVA 1Z4QA 1VDKA 1FURA 2JAWA 1YFEA 1Z4PX 4L57A 5HW2A 4HGVA 5EYVA 2PTSA 1KQ7A 1GK2A 1RE5A 2PFMA 3BWVA 4ADMA 1W27A 2O7EA 4YIKA 1IW7D 4C5RA 1U15A 4MX2A 3RD8A 4ADLA 4C5UA 1FUOA 2PTQA 3E04A 3QBPA 3CI0K 4BAAA 4V2RA 1XWOA 2RCNA 4L6CA 1B8FA 5M0JA 2QVEA 4CQ5A 4BABA 1K62A 3RRPA 3TV2A 1AUWA 2YIIA 2O6YA 3F4SA 4MWOA 3C8TA 4V2QA 3U19A 2FELA 3CRVA 4NLEA 2NYFA 3CZOA 5M0IA 2JAOA 1YFMA 1T9HA 2O7DA 1Z4LA 4WNLA 2VL7A 1DOFA 1Z4JA 4EFCA 4L6AA 4FLCA 1Z4IA 1XL8A 4NFLA 3R6QA 1HY1A 1U0LA 1XL7A 1XLYA 1T6PA 5H8WA 1FUQA 3R6VA 5F92A 2X75A 4EEIA 1XMCA 4YIHA 1C3UA 3GTDA 4MUMA 1JSWA 4APAA 1Q91A 2QGAB 2E9FA 4APBA 1Z4KA 2JARA 5EYTA 2FUSA 1J3UA 2HVGA 2RJSA 1TJWA 1YISA 1T6JA 1MH9A 2JAUA 4C6GA 1TJUA 1GKJA 2FENA 3KDZA 3UNVA 3NO9A 3GZHA 2J91A 2O7FA 2PTRA 3BHGA 5F91A 1GK3A
chains in the Genus database with same CATH topology
1Y2MA 3R6YA 4FFXA 1FUPA 1GKMA 1HY0A 1K7WA 3NZ4A 3OCFA 2O78A 3OCEA 2VD6A 1U16A 2NYNA 5D6BA 2O7BA 1I0AA 1TJ7A 2RJRA 2OHYA 4NSLA 1DCNA 4C5SA 1EB4A 3KDYA 1C3CA 1Q5NA 1TJVA 1VDKA 1FURA 1YFEA 5HW2A 4HGVA 5EYVA 2PTSA 1KQ7A 1GK2A 1RE5A 2PFMA 4ADMA 1W27A 2O7EA 4C5RA 1U15A 4MX2A 3RD8A 4ADLA 4C5UA 1FUOA 2PTQA 3E04A 3QBPA 4BAAA 4V2RA 1XWOA 1B8FA 2QVEA 4CQ5A 4BABA 3RRPA 1K62A 3TV2A 1AUWA 2YIIA 2O6YA 3C8TA 4V2QA 4NLEA 2NYFA 3CZOA 1YFMA 2O7DA 1DOFA 4EFCA 4FLCA 3R6QA 1HY1A 1T6PA 1FUQA 3R6VA 5F92A 2X75A 4EEIA 1C3UA 3GTDA 1JSWA 4APAA 2QGAB 2E9FA 4APBA 5EYTA 2FUSA 1J3UA 2HVGA 2RJSA 1TJWA 1YISA 1T6JA 4C6GA 1TJUA 1GKJA 3KDZA 3UNVA 3NO9A 3GZHA 2J91A 2O7FA 2PTRA 3BHGA 5F91A 1GK3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y2M A;  3R6Y A;  4FFX A;  1FUP A;  1GKM A;  1HY0 A;  1K7W A;  3NZ4 A;  3OCF A;  2O78 A;  3OCE A;  2VD6 A;  1U16 A;  2NYN A;  5D6B A;  2O7B A;  1I0A A;  1TJ7 A;  2RJR A;  2OHY A;  4NSL A;  1DCN A;  4C5S A;  1EB4 A;  3KDY A;  1C3C A;  1Q5N A;  1TJV A;  1VDK A;  1FUR A;  1YFE A;  5HW2 A;  4HGV A;  5EYV A;  2PTS A;  1KQ7 A;  1GK2 A;  1RE5 A;  2PFM A;  4ADM A;  1W27 A;  2O7E A;  4C5R A;  1U15 A;  4MX2 A;  3RD8 A;  4ADL A;  4C5U A;  1FUO A;  2PTQ A;  3E04 A;  3QBP A;  4BAA A;  4V2R A;  1XWO A;  1B8F A;  2QVE A;  4CQ5 A;  4BAB A;  3RRP A;  1K62 A;  3TV2 A;  1AUW A;  2YII A;  2O6Y A;  3C8T A;  4V2Q A;  4NLE A;  2NYF A;  3CZO A;  1YFM A;  2O7D A;  1DOF A;  4EFC A;  4FLC A;  3R6Q A;  1HY1 A;  1T6P A;  1FUQ A;  3R6V A;  5F92 A;  2X75 A;  4EEI A;  1C3U A;  3GTD A;  1JSW A;  4APA A;  2QGA B;  2E9F A;  4APB A;  5EYT A;  2FUS A;  1J3U A;  2HVG A;  2RJS A;  1TJW A;  1YIS A;  1T6J A;  4C6G A;  1TJU A;  1GKJ A;  3KDZ A;  3UNV A;  3NO9 A;  3GZH A;  2J91 A;  2O7F A;  2PTR A;  3BHG A;  5F91 A;  1GK3 A; 
#chains in the Genus database with same CATH topology
 1Y2M A;  3R6Y A;  2D28 C;  4FFX A;  4A15 A;  1FUP A;  1GKM A;  1HY0 A;  1K7W A;  1XMD A;  3NZ4 A;  3OCF A;  3U13 A;  2D27 A;  3F4R A;  2I7D A;  2O78 A;  3OCE A;  2VD6 A;  1U16 A;  3F4T A;  5D6B A;  2NYN A;  2O7B A;  1I0A A;  1Z4M A;  1TJ7 A;  2RJR A;  2OHY A;  4NSL A;  1DCN A;  4C5S A;  1EB4 A;  3KDY A;  3CRW 1;  2VSF A;  1C3C A;  1Q5N A;  4E88 A;  1Q92 A;  4IQJ M;  2YV5 A;  1TJV A;  1Z4Q A;  1VDK A;  1FUR A;  2JAW A;  1YFE A;  1Z4P X;  4L57 A;  5HW2 A;  4HGV A;  5EYV A;  2PTS A;  1KQ7 A;  1GK2 A;  1RE5 A;  2PFM A;  3BWV A;  4ADM A;  1W27 A;  2O7E A;  4YIK A;  1IW7 D;  4C5R A;  1U15 A;  4MX2 A;  3RD8 A;  4ADL A;  4C5U A;  1FUO A;  2PTQ A;  3E04 A;  3QBP A;  3CI0 K;  4BAA A;  4V2R A;  1XWO A;  2RCN A;  4L6C A;  1B8F A;  5M0J A;  2QVE A;  4CQ5 A;  4BAB A;  1K62 A;  3RRP A;  3TV2 A;  1AUW A;  2YII A;  2O6Y A;  3F4S A;  4MWO A;  3C8T A;  4V2Q A;  3U19 A;  2FEL A;  3CRV A;  4NLE A;  2NYF A;  3CZO A;  5M0I A;  2JAO A;  1YFM A;  1T9H A;  2O7D A;  1Z4L A;  4WNL A;  2VL7 A;  1DOF A;  1Z4J A;  4EFC A;  4L6A A;  4FLC A;  1Z4I A;  1XL8 A;  4NFL A;  3R6Q A;  1HY1 A;  1U0L A;  1XL7 A;  1XLY A;  1T6P A;  5H8W A;  1FUQ A;  3R6V A;  5F92 A;  2X75 A;  4EEI A;  1XMC A;  4YIH A;  1C3U A;  3GTD A;  4MUM A;  1JSW A;  4APA A;  1Q91 A;  2QGA B;  2E9F A;  4APB A;  1Z4K A;  2JAR A;  5EYT A;  2FUS A;  1J3U A;  2HVG A;  2RJS A;  1TJW A;  1YIS A;  1T6J A;  1MH9 A;  2JAU A;  4C6G A;  1TJU A;  1GKJ A;  2FEN A;  3KDZ A;  3UNV A;  3NO9 A;  3GZH A;  2J91 A;  2O7F A;  2PTR A;  3BHG A;  5F91 A;  1GK3 A; 
#chains in the Genus database with same CATH homology
 1Y2M A;  3R6Y A;  4FFX A;  1FUP A;  1GKM A;  1HY0 A;  1K7W A;  3NZ4 A;  3OCF A;  2O78 A;  3OCE A;  2VD6 A;  1U16 A;  2NYN A;  5D6B A;  2O7B A;  1I0A A;  1TJ7 A;  2RJR A;  2OHY A;  4NSL A;  1DCN A;  4C5S A;  1EB4 A;  3KDY A;  1C3C A;  1Q5N A;  1TJV A;  1VDK A;  1FUR A;  1YFE A;  5HW2 A;  4HGV A;  5EYV A;  2PTS A;  1KQ7 A;  1GK2 A;  1RE5 A;  2PFM A;  4ADM A;  1W27 A;  2O7E A;  4C5R A;  1U15 A;  4MX2 A;  3RD8 A;  4ADL A;  4C5U A;  1FUO A;  2PTQ A;  3E04 A;  3QBP A;  4BAA A;  4V2R A;  1XWO A;  1B8F A;  2QVE A;  4CQ5 A;  4BAB A;  3RRP A;  1K62 A;  3TV2 A;  1AUW A;  2YII A;  2O6Y A;  3C8T A;  4V2Q A;  4NLE A;  2NYF A;  3CZO A;  1YFM A;  2O7D A;  1DOF A;  4EFC A;  4FLC A;  3R6Q A;  1HY1 A;  1T6P A;  1FUQ A;  3R6V A;  5F92 A;  2X75 A;  4EEI A;  1C3U A;  3GTD A;  1JSW A;  4APA A;  2QGA B;  2E9F A;  4APB A;  5EYT A;  2FUS A;  1J3U A;  2HVG A;  2RJS A;  1TJW A;  1YIS A;  1T6J A;  4C6G A;  1TJU A;  1GKJ A;  3KDZ A;  3UNV A;  3NO9 A;  3GZH A;  2J91 A;  2O7F A;  2PTR A;  3BHG A;  5F91 A;  1GK3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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