1FUOA

Fumarase c with bound citrate
Total Genus 175
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
456
structure length
456
Chain Sequence
VRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Lyase
molecule keywords FUMARASE C
publication title Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli.
pubmed doi rcsb
source organism Escherichia coli
total genus 175
structure length 456
sequence length 456
chains with identical sequence B
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1996-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1fuoA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1fuoA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1fuoA02
1YFEA 1FUQA 3OCEA 1EB4A 3RD8A 2FUSA 2VD6A 1TJWA 1AUWA 1FUOA 1KQ7A 1T6JA 3GTDA 2O7DA 3QBPA 1J3UA 2NYFA 4ADMA 2RJRA 1YISA 2J91A 3C8TA 1GKJA 3RRPA 4V2RA 2RJSA 1C3UA 2NYNA 3R6VA 2X75A 3NO9A 3GZHA 2HVGA 3CZOA 2O7EA 3R6QA 1YFMA 4C5UA 1XWOA 2YIIA 1TJ7A 4NSLA 3TV2A 5F92A 4FFXA 3NZ4A 4ADLA 4C5SA 2O78A 3KDYA 1W27A 4BAAA 3OCFA 2QVEA 2E9FA 5HW2A 1Y2MA 4EFCA 1RE5A 4HGVA 1DCNA 2PTQA 1VDKA 1U15A 1K62A 5D6BA 1FUPA 1C3CA 4V2QA 5EYVA 1GKMA 4C6GA 1T6PA 2O7BA 1FURA 4APBA 1Q5NA 4APAA 1TJVA 3E04A 5F91A 1I0AA 1DOFA 2O6YA 4C5RA 1JSWA 1K7WA 1U16A 2PTSA 1GK2A 1GK3A 5EYTA 4CQ5A 2PTRA 2OHYA 4EEIA 1B8FA 2O7FA 4BABA 3KDZA 4MX2A 4FLCA 3R6YA 1HY1A 2QGAB 3UNVA 4NLEA 3BHGA 1TJUA 2PFMA 1HY0A
chains in the Genus database with same CATH superfamily
1YFEA 3F4SA 1FUQA 1Z4KA 3OCEA 1EB4A 3RD8A 2FUSA 2VD6A 1TJWA 1AUWA 1FUOA 1KQ7A 1MH9A 1T6JA 1XL7A 2D27A 3GTDA 2D28C 2O7DA 3F4RA 3QBPA 1J3UA 2NYFA 4ADMA 2RJRA 1YISA 2J91A 2VL7A 5M0JA 3CRVA 3C8TA 1GKJA 3RRPA 4V2RA 2RJSA 1C3UA 2FENA 3F4TA 2NYNA 3R6VA 3CRW1 2X75A 3BWVA 1Z4PX 3NO9A 3GZHA 2HVGA 3CZOA 2O7EA 2JAOA 3R6QA 2I7DA 1YFMA 1Z4MA 4C5UA 1XWOA 3CI0K 2YIIA 1TJ7A 4NSLA 2RCNA 3TV2A 5F92A 1Z4QA 4FFXA 3NZ4A 4ADLA 4C5SA 2O78A 3KDYA 4MWOA 4L6AA 4NFLA 1Z4IA 3OCFA 1W27A 4BAAA 5H8WA 2QVEA 2E9FA 5HW2A 1Y2MA 4EFCA 1RE5A 4HGVA 4YIKA 1DCNA 2PTQA 1Z4LA 1VDKA 1U15A 1K62A 5D6BA 1FUPA 4WNLA 4L57A 1C3CA 4V2QA 1XMCA 5EYVA 1T9HA 1GKMA 4A15A 4C6GA 1XMDA 1Z4JA 1XL8A 1Q92A 1T6PA 4L6CA 2O7BA 1Q91A 5M0IA 1FURA 4APBA 1Q5NA 3U19A 3U13A 4APAA 1TJVA 1IW7D 3E04A 1U0LA 5F91A 1I0AA 1DOFA 2O6YA 4C5RA 1JSWA 1K7WA 1U16A 2PTSA 4MUMA 4IQJM 2VSFA 1GK2A 4YIHA 1GK3A 5EYTA 4CQ5A 2PTRA 2OHYA 4EEIA 1B8FA 2O7FA 4E88A 4BABA 2JAWA 3KDZA 4MX2A 4FLCA 3R6YA 1HY1A 2QGAB 3UNVA 2JAUA 2YV5A 1XLYA 2FELA 4NLEA 3BHGA 1TJUA 2PFMA 2JARA 1HY0A
chains in the Genus database with same CATH topology
1YFEA 1FUQA 3OCEA 1EB4A 3RD8A 2FUSA 2VD6A 1TJWA 1AUWA 1FUOA 1KQ7A 1T6JA 3GTDA 2O7DA 3QBPA 1J3UA 2NYFA 4ADMA 2RJRA 1YISA 2J91A 3C8TA 1GKJA 3RRPA 4V2RA 2RJSA 1C3UA 2NYNA 3R6VA 2X75A 3NO9A 3GZHA 2HVGA 3CZOA 2O7EA 3R6QA 1YFMA 4C5UA 1XWOA 2YIIA 1TJ7A 4NSLA 3TV2A 5F92A 4FFXA 3NZ4A 4ADLA 4C5SA 2O78A 3KDYA 1W27A 4BAAA 3OCFA 2QVEA 2E9FA 5HW2A 1Y2MA 4EFCA 1RE5A 4HGVA 1DCNA 2PTQA 1VDKA 1U15A 1K62A 5D6BA 1FUPA 1C3CA 4V2QA 5EYVA 1GKMA 4C6GA 1T6PA 2O7BA 1FURA 4APBA 1Q5NA 4APAA 1TJVA 3E04A 5F91A 1I0AA 1DOFA 2O6YA 4C5RA 1JSWA 1K7WA 1U16A 2PTSA 1GK2A 1GK3A 5EYTA 4CQ5A 2PTRA 2OHYA 4EEIA 1B8FA 2O7FA 4BABA 3KDZA 4MX2A 4FLCA 3R6YA 1HY1A 2QGAB 3UNVA 4NLEA 3BHGA 1TJUA 2PFMA 1HY0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YFE A;  1FUQ A;  3OCE A;  1EB4 A;  3RD8 A;  2FUS A;  2VD6 A;  1TJW A;  1AUW A;  1FUO A;  1KQ7 A;  1T6J A;  3GTD A;  2O7D A;  3QBP A;  1J3U A;  2NYF A;  4ADM A;  2RJR A;  1YIS A;  2J91 A;  3C8T A;  1GKJ A;  3RRP A;  4V2R A;  2RJS A;  1C3U A;  2NYN A;  3R6V A;  2X75 A;  3NO9 A;  3GZH A;  2HVG A;  3CZO A;  2O7E A;  3R6Q A;  1YFM A;  4C5U A;  1XWO A;  2YII A;  1TJ7 A;  4NSL A;  3TV2 A;  5F92 A;  4FFX A;  3NZ4 A;  4ADL A;  4C5S A;  2O78 A;  3KDY A;  1W27 A;  4BAA A;  3OCF A;  2QVE A;  2E9F A;  5HW2 A;  1Y2M A;  4EFC A;  1RE5 A;  4HGV A;  1DCN A;  2PTQ A;  1VDK A;  1U15 A;  1K62 A;  5D6B A;  1FUP A;  1C3C A;  4V2Q A;  5EYV A;  1GKM A;  4C6G A;  1T6P A;  2O7B A;  1FUR A;  4APB A;  1Q5N A;  4APA A;  1TJV A;  3E04 A;  5F91 A;  1I0A A;  1DOF A;  2O6Y A;  4C5R A;  1JSW A;  1K7W A;  1U16 A;  2PTS A;  1GK2 A;  1GK3 A;  5EYT A;  4CQ5 A;  2PTR A;  2OHY A;  4EEI A;  1B8F A;  2O7F A;  4BAB A;  3KDZ A;  4MX2 A;  4FLC A;  3R6Y A;  1HY1 A;  2QGA B;  3UNV A;  4NLE A;  3BHG A;  1TJU A;  2PFM A;  1HY0 A; 
#chains in the Genus database with same CATH topology
 1YFE A;  3F4S A;  1FUQ A;  1Z4K A;  3OCE A;  1EB4 A;  3RD8 A;  2FUS A;  2VD6 A;  1TJW A;  1AUW A;  1FUO A;  1KQ7 A;  1MH9 A;  1T6J A;  1XL7 A;  2D27 A;  3GTD A;  2D28 C;  2O7D A;  3F4R A;  3QBP A;  1J3U A;  2NYF A;  4ADM A;  2RJR A;  1YIS A;  2J91 A;  2VL7 A;  5M0J A;  3CRV A;  3C8T A;  1GKJ A;  3RRP A;  4V2R A;  2RJS A;  1C3U A;  2FEN A;  3F4T A;  2NYN A;  3R6V A;  3CRW 1;  2X75 A;  3BWV A;  1Z4P X;  3NO9 A;  3GZH A;  2HVG A;  3CZO A;  2O7E A;  2JAO A;  3R6Q A;  2I7D A;  1YFM A;  1Z4M A;  4C5U A;  1XWO A;  3CI0 K;  2YII A;  1TJ7 A;  4NSL A;  2RCN A;  3TV2 A;  5F92 A;  1Z4Q A;  4FFX A;  3NZ4 A;  4ADL A;  4C5S A;  2O78 A;  3KDY A;  4MWO A;  4L6A A;  4NFL A;  1Z4I A;  3OCF A;  1W27 A;  4BAA A;  5H8W A;  2QVE A;  2E9F A;  5HW2 A;  1Y2M A;  4EFC A;  1RE5 A;  4HGV A;  4YIK A;  1DCN A;  2PTQ A;  1Z4L A;  1VDK A;  1U15 A;  1K62 A;  5D6B A;  1FUP A;  4WNL A;  4L57 A;  1C3C A;  4V2Q A;  1XMC A;  5EYV A;  1T9H A;  1GKM A;  4A15 A;  4C6G A;  1XMD A;  1Z4J A;  1XL8 A;  1Q92 A;  1T6P A;  4L6C A;  2O7B A;  1Q91 A;  5M0I A;  1FUR A;  4APB A;  1Q5N A;  3U19 A;  3U13 A;  4APA A;  1TJV A;  1IW7 D;  3E04 A;  1U0L A;  5F91 A;  1I0A A;  1DOF A;  2O6Y A;  4C5R A;  1JSW A;  1K7W A;  1U16 A;  2PTS A;  4MUM A;  4IQJ M;  2VSF A;  1GK2 A;  4YIH A;  1GK3 A;  5EYT A;  4CQ5 A;  2PTR A;  2OHY A;  4EEI A;  1B8F A;  2O7F A;  4E88 A;  4BAB A;  2JAW A;  3KDZ A;  4MX2 A;  4FLC A;  3R6Y A;  1HY1 A;  2QGA B;  3UNV A;  2JAU A;  2YV5 A;  1XLY A;  2FEL A;  4NLE A;  3BHG A;  1TJU A;  2PFM A;  2JAR A;  1HY0 A; 
#chains in the Genus database with same CATH homology
 1YFE A;  1FUQ A;  3OCE A;  1EB4 A;  3RD8 A;  2FUS A;  2VD6 A;  1TJW A;  1AUW A;  1FUO A;  1KQ7 A;  1T6J A;  3GTD A;  2O7D A;  3QBP A;  1J3U A;  2NYF A;  4ADM A;  2RJR A;  1YIS A;  2J91 A;  3C8T A;  1GKJ A;  3RRP A;  4V2R A;  2RJS A;  1C3U A;  2NYN A;  3R6V A;  2X75 A;  3NO9 A;  3GZH A;  2HVG A;  3CZO A;  2O7E A;  3R6Q A;  1YFM A;  4C5U A;  1XWO A;  2YII A;  1TJ7 A;  4NSL A;  3TV2 A;  5F92 A;  4FFX A;  3NZ4 A;  4ADL A;  4C5S A;  2O78 A;  3KDY A;  1W27 A;  4BAA A;  3OCF A;  2QVE A;  2E9F A;  5HW2 A;  1Y2M A;  4EFC A;  1RE5 A;  4HGV A;  1DCN A;  2PTQ A;  1VDK A;  1U15 A;  1K62 A;  5D6B A;  1FUP A;  1C3C A;  4V2Q A;  5EYV A;  1GKM A;  4C6G A;  1T6P A;  2O7B A;  1FUR A;  4APB A;  1Q5N A;  4APA A;  1TJV A;  3E04 A;  5F91 A;  1I0A A;  1DOF A;  2O6Y A;  4C5R A;  1JSW A;  1K7W A;  1U16 A;  2PTS A;  1GK2 A;  1GK3 A;  5EYT A;  4CQ5 A;  2PTR A;  2OHY A;  4EEI A;  1B8F A;  2O7F A;  4BAB A;  3KDZ A;  4MX2 A;  4FLC A;  3R6Y A;  1HY1 A;  2QGA B;  3UNV A;  4NLE A;  3BHG A;  1TJU A;  2PFM A;  1HY0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...