1FUOA

Fumarase c with bound citrate
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
456
structure length
456
Chain Sequence
VRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords FUMARASE C
publication title Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
total genus 175
structure length 456
sequence length 456
chains with identical sequence B
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1996-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1fuoA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1fuoA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1fuoA02
3TV2A 2PTSA 3GZHA 4MX2A 4APAA 2NYFA 1DCNA 3RRPA 4HGVA 4EFCA 2O7DA 2X75A 3R6QA 1I0AA 4ADMA 1FUQA 1K7WA 2PTQA 1JSWA 5F92A 1AUWA 2PTRA 1B8FA 3GTDA 1TJVA 1TJWA 3NZ4A 3C8TA 3OCFA 3OCEA 2QVEA 4BAAA 1Y2MA 2YIIA 3KDYA 1C3CA 1XWOA 1GKJA 1YISA 1YFMA 2O7FA 5EYVA 4EEIA 5HW2A 1GK3A 2NYNA 3KDZA 4NSLA 4BABA 3E04A 2J91A 1TJUA 2E9FA 4CQ5A 1EB4A 2OHYA 4FLCA 2RJRA 1U15A 1RE5A 1VDKA 2FUSA 1GK2A 1FURA 2O78A 4C5UA 1KQ7A 4FFXA 4C5RA 1HY0A 3QBPA 1GKMA 1Q5NA 1J3UA 5D6BA 2PFMA 3BHGA 2RJSA 4C5SA 4V2QA 1C3UA 1DOFA 5F91A 3CZOA 3R6VA 2O7EA 1TJ7A 1T6JA 2HVGA 4APBA 3UNVA 1U16A 1K62A 4NLEA 1YFEA 2O7BA 4V2RA 5EYTA 4C6GA 2VD6A 4ADLA 1HY1A 1FUPA 1W27A 1FUOA 2O6YA 3R6YA 2QGAB 1T6PA 3NO9A 3RD8A
chains in the Genus database with same CATH superfamily
1Z4MA 5H8WA 2FENA 3TV2A 2PTSA 3F4SA 3GZHA 4MX2A 4APAA 2NYFA 1DCNA 3RRPA 4HGVA 4L6AA 4EFCA 2O7DA 2VL7A 2X75A 4MUMA 3R6QA 1Q91A 5M0JA 1I0AA 4ADMA 4MWOA 1FUQA 1Z4JA 1K7WA 2PTQA 1JSWA 5F92A 1Z4IA 2D28C 1AUWA 2PTRA 1B8FA 1XMDA 3GTDA 1TJVA 1TJWA 3NZ4A 4YIKA 3C8TA 3OCFA 4WNLA 5M0IA 3OCEA 2QVEA 4BAAA 1Y2MA 1Q92A 2D27A 2YIIA 1MH9A 1T6PA 1XMCA 3KDYA 1C3CA 1XWOA 1GKJA 1YISA 2O7FA 5EYVA 4IQJM 4EEIA 2JAWA 1T9HA 5HW2A 1GK3A 2NYNA 3KDZA 1Z4PX 4NSLA 4BABA 3E04A 2J91A 1TJUA 1IW7D 2E9FA 4CQ5A 1EB4A 2OHYA 4FLCA 2RJRA 1U15A 1RE5A 1VDKA 2FUSA 1GK2A 1FURA 2O78A 4C5UA 1KQ7A 3CRVA 4FFXA 3CI0K 4C5RA 1HY0A 3U13A 1XL7A 3QBPA 4L6CA 4NFLA 1GKMA 2FELA 1J3UA 1Q5NA 1Z4QA 5D6BA 2PFMA 1XLYA 3BHGA 2RJSA 3F4TA 4C5SA 2JAOA 1Z4KA 4V2QA 1C3UA 1DOFA 1U0LA 5F91A 4YIHA 3U19A 3BWVA 3CZOA 2JAUA 3R6VA 2O7EA 2I7DA 1TJ7A 1T6JA 2HVGA 4E88A 3CRW1 4APBA 1XL8A 3F4RA 3UNVA 1U16A 1K62A 4NLEA 1YFEA 2O7BA 4V2RA 5EYTA 4C6GA 2VD6A 2YV5A 4ADLA 2JARA 1HY1A 1FUPA 1W27A 4L57A 1FUOA 2O6YA 2VSFA 2RCNA 4A15A 1Z4LA 3R6YA 2QGAB 1YFMA 3NO9A 3RD8A
chains in the Genus database with same CATH topology
3TV2A 2PTSA 3GZHA 4MX2A 4APAA 2NYFA 1DCNA 3RRPA 4HGVA 4EFCA 2O7DA 2X75A 3R6QA 1I0AA 4ADMA 1FUQA 1K7WA 2PTQA 1JSWA 5F92A 1AUWA 2PTRA 1B8FA 3GTDA 1TJVA 1TJWA 3NZ4A 3C8TA 3OCFA 3OCEA 2QVEA 4BAAA 1Y2MA 2YIIA 3KDYA 1C3CA 1XWOA 1GKJA 1YISA 1YFMA 2O7FA 5EYVA 4EEIA 5HW2A 1GK3A 2NYNA 3KDZA 4NSLA 4BABA 3E04A 2J91A 1TJUA 2E9FA 4CQ5A 1EB4A 2OHYA 4FLCA 2RJRA 1U15A 1RE5A 1VDKA 2FUSA 1GK2A 1FURA 2O78A 4C5UA 1KQ7A 4FFXA 4C5RA 1HY0A 3QBPA 1GKMA 1Q5NA 1J3UA 5D6BA 2PFMA 3BHGA 2RJSA 4C5SA 4V2QA 1C3UA 1DOFA 5F91A 3CZOA 3R6VA 2O7EA 1TJ7A 1T6JA 2HVGA 4APBA 3UNVA 1U16A 1K62A 4NLEA 1YFEA 2O7BA 4V2RA 5EYTA 4C6GA 2VD6A 4ADLA 1HY1A 1FUPA 1W27A 1FUOA 2O6YA 3R6YA 2QGAB 1T6PA 3NO9A 3RD8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TV2 A;  2PTS A;  3GZH A;  4MX2 A;  4APA A;  2NYF A;  1DCN A;  3RRP A;  4HGV A;  4EFC A;  2O7D A;  2X75 A;  3R6Q A;  1I0A A;  4ADM A;  1FUQ A;  1K7W A;  2PTQ A;  1JSW A;  5F92 A;  1AUW A;  2PTR A;  1B8F A;  3GTD A;  1TJV A;  1TJW A;  3NZ4 A;  3C8T A;  3OCF A;  3OCE A;  2QVE A;  4BAA A;  1Y2M A;  2YII A;  3KDY A;  1C3C A;  1XWO A;  1GKJ A;  1YIS A;  1YFM A;  2O7F A;  5EYV A;  4EEI A;  5HW2 A;  1GK3 A;  2NYN A;  3KDZ A;  4NSL A;  4BAB A;  3E04 A;  2J91 A;  1TJU A;  2E9F A;  4CQ5 A;  1EB4 A;  2OHY A;  4FLC A;  2RJR A;  1U15 A;  1RE5 A;  1VDK A;  2FUS A;  1GK2 A;  1FUR A;  2O78 A;  4C5U A;  1KQ7 A;  4FFX A;  4C5R A;  1HY0 A;  3QBP A;  1GKM A;  1Q5N A;  1J3U A;  5D6B A;  2PFM A;  3BHG A;  2RJS A;  4C5S A;  4V2Q A;  1C3U A;  1DOF A;  5F91 A;  3CZO A;  3R6V A;  2O7E A;  1TJ7 A;  1T6J A;  2HVG A;  4APB A;  3UNV A;  1U16 A;  1K62 A;  4NLE A;  1YFE A;  2O7B A;  4V2R A;  5EYT A;  4C6G A;  2VD6 A;  4ADL A;  1HY1 A;  1FUP A;  1W27 A;  1FUO A;  2O6Y A;  3R6Y A;  2QGA B;  1T6P A;  3NO9 A;  3RD8 A; 
#chains in the Genus database with same CATH topology
 1Z4M A;  5H8W A;  2FEN A;  3TV2 A;  2PTS A;  3F4S A;  3GZH A;  4MX2 A;  4APA A;  2NYF A;  1DCN A;  3RRP A;  4HGV A;  4L6A A;  4EFC A;  2O7D A;  2VL7 A;  2X75 A;  4MUM A;  3R6Q A;  1Q91 A;  5M0J A;  1I0A A;  4ADM A;  4MWO A;  1FUQ A;  1Z4J A;  1K7W A;  2PTQ A;  1JSW A;  5F92 A;  1Z4I A;  2D28 C;  1AUW A;  2PTR A;  1B8F A;  1XMD A;  3GTD A;  1TJV A;  1TJW A;  3NZ4 A;  4YIK A;  3C8T A;  3OCF A;  4WNL A;  5M0I A;  3OCE A;  2QVE A;  4BAA A;  1Y2M A;  1Q92 A;  2D27 A;  2YII A;  1MH9 A;  1T6P A;  1XMC A;  3KDY A;  1C3C A;  1XWO A;  1GKJ A;  1YIS A;  2O7F A;  5EYV A;  4IQJ M;  4EEI A;  2JAW A;  1T9H A;  5HW2 A;  1GK3 A;  2NYN A;  3KDZ A;  1Z4P X;  4NSL A;  4BAB A;  3E04 A;  2J91 A;  1TJU A;  1IW7 D;  2E9F A;  4CQ5 A;  1EB4 A;  2OHY A;  4FLC A;  2RJR A;  1U15 A;  1RE5 A;  1VDK A;  2FUS A;  1GK2 A;  1FUR A;  2O78 A;  4C5U A;  1KQ7 A;  3CRV A;  4FFX A;  3CI0 K;  4C5R A;  1HY0 A;  3U13 A;  1XL7 A;  3QBP A;  4L6C A;  4NFL A;  1GKM A;  2FEL A;  1J3U A;  1Q5N A;  1Z4Q A;  5D6B A;  2PFM A;  1XLY A;  3BHG A;  2RJS A;  3F4T A;  4C5S A;  2JAO A;  1Z4K A;  4V2Q A;  1C3U A;  1DOF A;  1U0L A;  5F91 A;  4YIH A;  3U19 A;  3BWV A;  3CZO A;  2JAU A;  3R6V A;  2O7E A;  2I7D A;  1TJ7 A;  1T6J A;  2HVG A;  4E88 A;  3CRW 1;  4APB A;  1XL8 A;  3F4R A;  3UNV A;  1U16 A;  1K62 A;  4NLE A;  1YFE A;  2O7B A;  4V2R A;  5EYT A;  4C6G A;  2VD6 A;  2YV5 A;  4ADL A;  2JAR A;  1HY1 A;  1FUP A;  1W27 A;  4L57 A;  1FUO A;  2O6Y A;  2VSF A;  2RCN A;  4A15 A;  1Z4L A;  3R6Y A;  2QGA B;  1YFM A;  3NO9 A;  3RD8 A; 
#chains in the Genus database with same CATH homology
 3TV2 A;  2PTS A;  3GZH A;  4MX2 A;  4APA A;  2NYF A;  1DCN A;  3RRP A;  4HGV A;  4EFC A;  2O7D A;  2X75 A;  3R6Q A;  1I0A A;  4ADM A;  1FUQ A;  1K7W A;  2PTQ A;  1JSW A;  5F92 A;  1AUW A;  2PTR A;  1B8F A;  3GTD A;  1TJV A;  1TJW A;  3NZ4 A;  3C8T A;  3OCF A;  3OCE A;  2QVE A;  4BAA A;  1Y2M A;  2YII A;  3KDY A;  1C3C A;  1XWO A;  1GKJ A;  1YIS A;  1YFM A;  2O7F A;  5EYV A;  4EEI A;  5HW2 A;  1GK3 A;  2NYN A;  3KDZ A;  4NSL A;  4BAB A;  3E04 A;  2J91 A;  1TJU A;  2E9F A;  4CQ5 A;  1EB4 A;  2OHY A;  4FLC A;  2RJR A;  1U15 A;  1RE5 A;  1VDK A;  2FUS A;  1GK2 A;  1FUR A;  2O78 A;  4C5U A;  1KQ7 A;  4FFX A;  4C5R A;  1HY0 A;  3QBP A;  1GKM A;  1Q5N A;  1J3U A;  5D6B A;  2PFM A;  3BHG A;  2RJS A;  4C5S A;  4V2Q A;  1C3U A;  1DOF A;  5F91 A;  3CZO A;  3R6V A;  2O7E A;  1TJ7 A;  1T6J A;  2HVG A;  4APB A;  3UNV A;  1U16 A;  1K62 A;  4NLE A;  1YFE A;  2O7B A;  4V2R A;  5EYT A;  4C6G A;  2VD6 A;  4ADL A;  1HY1 A;  1FUP A;  1W27 A;  1FUO A;  2O6Y A;  3R6Y A;  2QGA B;  1T6P A;  3NO9 A;  3RD8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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