1FUOA

Fumarase c with bound citrate
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
456
structure length
456
Chain Sequence
VRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
molecule keywords FUMARASE C
total genus 175
structure length 456
sequence length 456
chains with identical sequence B
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1996-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1fuoA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1fuoA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1fuoA02
5F91A 5HW2A 1YFMA 2HVGA 4ADMA 4APBA 1DOFA 2E9FA 1GK3A 2O78A 1GKJA 1Y2MA 1FUQA 2FUSA 3KDYA 1VDKA 4EFCA 1Q5NA 3NZ4A 1FURA 5D6BA 1HY1A 4C6GA 2O7BA 5EYTA 3R6YA 2O7EA 2QVEA 1XWOA 4CQ5A 1W27A 3RRPA 3OCFA 1FUOA 4BAAA 1TJUA 3NO9A 2NYNA 2O7FA 1HY0A 1T6JA 1K7WA 5F92A 4C5RA 4ADLA 3KDZA 2PTQA 1TJ7A 1I0AA 2RJRA 2QGAB 4FLCA 2O6YA 1RE5A 2J91A 4NLEA 1TJWA 1DCNA 2O7DA 1U15A 1K62A 3GTDA 2VD6A 1T6PA 2RJSA 1B8FA 1FUPA 1KQ7A 3OCEA 3R6QA 2NYFA 4EEIA 2OHYA 2YIIA 1GKMA 1YISA 4MX2A 1AUWA 2X75A 4APAA 1TJVA 3TV2A 1GK2A 4FFXA 2PTRA 4C5SA 1EB4A 5EYVA 2PTSA 1YFEA 3C8TA 1J3UA 1JSWA 3CZOA 4V2RA 3QBPA 4BABA 3R6VA 3UNVA 1C3CA 3E04A 1C3UA 4HGVA 3RD8A 4NSLA 2PFMA 4V2QA 4C5UA 3BHGA 1U16A 3GZHA
chains in the Genus database with same CATH superfamily
5F91A 4L57A 1YFMA 4E88A 2HVGA 4ADMA 4L6AA 4APBA 5HW2A 1Z4QA 4MWOA 3U13A 2JAWA 1DOFA 2E9FA 1GK3A 1Z4JA 1Z4MA 2O78A 1GKJA 1Y2MA 1FUQA 3CI0K 2FUSA 3KDYA 1VDKA 4EFCA 3F4RA 1Q5NA 3NZ4A 1FURA 5D6BA 1HY1A 4C6GA 1XL7A 2O7BA 1XL8A 1MH9A 5EYTA 3R6YA 2O7EA 2QVEA 2JAOA 4WNLA 1XWOA 4CQ5A 2RCNA 1W27A 3RRPA 3OCFA 1XMDA 4YIHA 1FUOA 5M0JA 2D28C 4BAAA 1TJUA 3BWVA 3NO9A 2NYNA 2O7FA 1HY0A 4IQJM 1T6JA 1Z4PX 1K7WA 3CRVA 5F92A 1IW7D 1Z4IA 4C5RA 4ADLA 3KDZA 2PTQA 1TJ7A 2VL7A 1I0AA 1T9HA 2FELA 2RJRA 2QGAB 4FLCA 2D27A 2O6YA 1RE5A 2J91A 4NLEA 1TJWA 1DCNA 2O7DA 1U15A 1K62A 3GTDA 2JARA 2VD6A 1U0LA 1Z4KA 1T6PA 3CRW1 2RJSA 2I7DA 1B8FA 1FUPA 4A15A 1KQ7A 4YIKA 5H8WA 3OCEA 4L6CA 3R6QA 2VSFA 2NYFA 1Z4LA 4EEIA 2OHYA 2YIIA 1GKMA 1YISA 4MX2A 1AUWA 2X75A 4APAA 1TJVA 3F4SA 3TV2A 4MUMA 1GK2A 4FFXA 2PTRA 4C5SA 1EB4A 5EYVA 2PTSA 3F4TA 5M0IA 2FENA 1YFEA 3C8TA 1J3UA 1JSWA 3CZOA 4V2RA 3QBPA 2YV5A 4BABA 1XLYA 3R6VA 3UNVA 1C3CA 3E04A 1C3UA 4HGVA 4NFLA 1XMCA 3RD8A 2JAUA 4NSLA 3U19A 2PFMA 4V2QA 1Q92A 4C5UA 1Q91A 3BHGA 1U16A 3GZHA
chains in the Genus database with same CATH topology
5F91A 5HW2A 1YFMA 2HVGA 4ADMA 4APBA 1DOFA 2E9FA 1GK3A 2O78A 1GKJA 1Y2MA 1FUQA 2FUSA 3KDYA 1VDKA 4EFCA 1Q5NA 3NZ4A 1FURA 5D6BA 1HY1A 4C6GA 2O7BA 5EYTA 3R6YA 2O7EA 2QVEA 1XWOA 4CQ5A 1W27A 3RRPA 3OCFA 1FUOA 4BAAA 1TJUA 3NO9A 2NYNA 2O7FA 1HY0A 1T6JA 1K7WA 5F92A 4C5RA 4ADLA 3KDZA 2PTQA 1TJ7A 1I0AA 2RJRA 2QGAB 4FLCA 2O6YA 1RE5A 2J91A 4NLEA 1TJWA 1DCNA 2O7DA 1U15A 1K62A 3GTDA 2VD6A 1T6PA 2RJSA 1B8FA 1FUPA 1KQ7A 3OCEA 3R6QA 2NYFA 4EEIA 2OHYA 2YIIA 1GKMA 1YISA 4MX2A 1AUWA 2X75A 4APAA 1TJVA 3TV2A 1GK2A 4FFXA 2PTRA 4C5SA 1EB4A 5EYVA 2PTSA 1YFEA 3C8TA 1J3UA 1JSWA 3CZOA 4V2RA 3QBPA 4BABA 3R6VA 3UNVA 1C3CA 3E04A 1C3UA 4HGVA 3RD8A 4NSLA 2PFMA 4V2QA 4C5UA 3BHGA 1U16A 3GZHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F91 A;  5HW2 A;  1YFM A;  2HVG A;  4ADM A;  4APB A;  1DOF A;  2E9F A;  1GK3 A;  2O78 A;  1GKJ A;  1Y2M A;  1FUQ A;  2FUS A;  3KDY A;  1VDK A;  4EFC A;  1Q5N A;  3NZ4 A;  1FUR A;  5D6B A;  1HY1 A;  4C6G A;  2O7B A;  5EYT A;  3R6Y A;  2O7E A;  2QVE A;  1XWO A;  4CQ5 A;  1W27 A;  3RRP A;  3OCF A;  1FUO A;  4BAA A;  1TJU A;  3NO9 A;  2NYN A;  2O7F A;  1HY0 A;  1T6J A;  1K7W A;  5F92 A;  4C5R A;  4ADL A;  3KDZ A;  2PTQ A;  1TJ7 A;  1I0A A;  2RJR A;  2QGA B;  4FLC A;  2O6Y A;  1RE5 A;  2J91 A;  4NLE A;  1TJW A;  1DCN A;  2O7D A;  1U15 A;  1K62 A;  3GTD A;  2VD6 A;  1T6P A;  2RJS A;  1B8F A;  1FUP A;  1KQ7 A;  3OCE A;  3R6Q A;  2NYF A;  4EEI A;  2OHY A;  2YII A;  1GKM A;  1YIS A;  4MX2 A;  1AUW A;  2X75 A;  4APA A;  1TJV A;  3TV2 A;  1GK2 A;  4FFX A;  2PTR A;  4C5S A;  1EB4 A;  5EYV A;  2PTS A;  1YFE A;  3C8T A;  1J3U A;  1JSW A;  3CZO A;  4V2R A;  3QBP A;  4BAB A;  3R6V A;  3UNV A;  1C3C A;  3E04 A;  1C3U A;  4HGV A;  3RD8 A;  4NSL A;  2PFM A;  4V2Q A;  4C5U A;  3BHG A;  1U16 A;  3GZH A; 
#chains in the Genus database with same CATH topology
 5F91 A;  4L57 A;  1YFM A;  4E88 A;  2HVG A;  4ADM A;  4L6A A;  4APB A;  5HW2 A;  1Z4Q A;  4MWO A;  3U13 A;  2JAW A;  1DOF A;  2E9F A;  1GK3 A;  1Z4J A;  1Z4M A;  2O78 A;  1GKJ A;  1Y2M A;  1FUQ A;  3CI0 K;  2FUS A;  3KDY A;  1VDK A;  4EFC A;  3F4R A;  1Q5N A;  3NZ4 A;  1FUR A;  5D6B A;  1HY1 A;  4C6G A;  1XL7 A;  2O7B A;  1XL8 A;  1MH9 A;  5EYT A;  3R6Y A;  2O7E A;  2QVE A;  2JAO A;  4WNL A;  1XWO A;  4CQ5 A;  2RCN A;  1W27 A;  3RRP A;  3OCF A;  1XMD A;  4YIH A;  1FUO A;  5M0J A;  2D28 C;  4BAA A;  1TJU A;  3BWV A;  3NO9 A;  2NYN A;  2O7F A;  1HY0 A;  4IQJ M;  1T6J A;  1Z4P X;  1K7W A;  3CRV A;  5F92 A;  1IW7 D;  1Z4I A;  4C5R A;  4ADL A;  3KDZ A;  2PTQ A;  1TJ7 A;  2VL7 A;  1I0A A;  1T9H A;  2FEL A;  2RJR A;  2QGA B;  4FLC A;  2D27 A;  2O6Y A;  1RE5 A;  2J91 A;  4NLE A;  1TJW A;  1DCN A;  2O7D A;  1U15 A;  1K62 A;  3GTD A;  2JAR A;  2VD6 A;  1U0L A;  1Z4K A;  1T6P A;  3CRW 1;  2RJS A;  2I7D A;  1B8F A;  1FUP A;  4A15 A;  1KQ7 A;  4YIK A;  5H8W A;  3OCE A;  4L6C A;  3R6Q A;  2VSF A;  2NYF A;  1Z4L A;  4EEI A;  2OHY A;  2YII A;  1GKM A;  1YIS A;  4MX2 A;  1AUW A;  2X75 A;  4APA A;  1TJV A;  3F4S A;  3TV2 A;  4MUM A;  1GK2 A;  4FFX A;  2PTR A;  4C5S A;  1EB4 A;  5EYV A;  2PTS A;  3F4T A;  5M0I A;  2FEN A;  1YFE A;  3C8T A;  1J3U A;  1JSW A;  3CZO A;  4V2R A;  3QBP A;  2YV5 A;  4BAB A;  1XLY A;  3R6V A;  3UNV A;  1C3C A;  3E04 A;  1C3U A;  4HGV A;  4NFL A;  1XMC A;  3RD8 A;  2JAU A;  4NSL A;  3U19 A;  2PFM A;  4V2Q A;  1Q92 A;  4C5U A;  1Q91 A;  3BHG A;  1U16 A;  3GZH A; 
#chains in the Genus database with same CATH homology
 5F91 A;  5HW2 A;  1YFM A;  2HVG A;  4ADM A;  4APB A;  1DOF A;  2E9F A;  1GK3 A;  2O78 A;  1GKJ A;  1Y2M A;  1FUQ A;  2FUS A;  3KDY A;  1VDK A;  4EFC A;  1Q5N A;  3NZ4 A;  1FUR A;  5D6B A;  1HY1 A;  4C6G A;  2O7B A;  5EYT A;  3R6Y A;  2O7E A;  2QVE A;  1XWO A;  4CQ5 A;  1W27 A;  3RRP A;  3OCF A;  1FUO A;  4BAA A;  1TJU A;  3NO9 A;  2NYN A;  2O7F A;  1HY0 A;  1T6J A;  1K7W A;  5F92 A;  4C5R A;  4ADL A;  3KDZ A;  2PTQ A;  1TJ7 A;  1I0A A;  2RJR A;  2QGA B;  4FLC A;  2O6Y A;  1RE5 A;  2J91 A;  4NLE A;  1TJW A;  1DCN A;  2O7D A;  1U15 A;  1K62 A;  3GTD A;  2VD6 A;  1T6P A;  2RJS A;  1B8F A;  1FUP A;  1KQ7 A;  3OCE A;  3R6Q A;  2NYF A;  4EEI A;  2OHY A;  2YII A;  1GKM A;  1YIS A;  4MX2 A;  1AUW A;  2X75 A;  4APA A;  1TJV A;  3TV2 A;  1GK2 A;  4FFX A;  2PTR A;  4C5S A;  1EB4 A;  5EYV A;  2PTS A;  1YFE A;  3C8T A;  1J3U A;  1JSW A;  3CZO A;  4V2R A;  3QBP A;  4BAB A;  3R6V A;  3UNV A;  1C3C A;  3E04 A;  1C3U A;  4HGV A;  3RD8 A;  4NSL A;  2PFM A;  4V2Q A;  4C5U A;  3BHG A;  1U16 A;  3GZH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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