1FUOA

Fumarase c with bound citrate
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
456
structure length
456
Chain Sequence
b'VRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQM'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords FUMARASE C
publication title Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
total genus 175
structure length 456
sequence length 456
chains with identical sequence B
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1996-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1fuoA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1fuoA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1fuoA02
2FUSA 2PTSA 3KDZA 4APBA 1T6JA 5EYTA 5F91A 3R6QA 2VD6A 1YFEA 3UNVA 1EB4A 5EYVA 4HGVA 1TJUA 2O7BA 4ADLA 4C5UA 1JSWA 4NSLA 2O6YA 1Y2MA 2HVGA 2NYFA 1W27A 4ADMA 4FLCA 1T6PA 2PTQA 2J91A 4MX2A 2QVEA 5HW2A 2X75A 1FURA 1GK3A 2QGAB 3BHGA 1FUQA 3GTDA 1B8FA 3RD8A 2E9FA 3NO9A 1AUWA 1K7WA 1FUOA 3GZHA 2OHYA 1HY0A 1YFMA 1Q5NA 2PTRA 1TJWA 3R6VA 1YISA 4BAAA 3RRPA 1TJ7A 4FFXA 3C8TA 1I0AA 1K62A 2O7DA 4EEIA 3OCFA 3QBPA 4NLEA 1DCNA 2RJSA 1C3CA 2YIIA 3CZOA 3OCEA 1C3UA 2O7EA 2O7FA 1U16A 1GK2A 1DOFA 2PFMA 4C6GA 3NZ4A 2RJRA 4V2QA 1J3UA 1FUPA 3R6YA 1TJVA 3KDYA 2O78A 5D6BA 4EFCA 4C5SA 4APAA 1GKMA 3TV2A 1XWOA 1GKJA 5F92A 4C5RA 3E04A 4V2RA 1VDKA 4BABA 2NYNA 1KQ7A 4CQ5A 1HY1A 1U15A 1RE5A
chains in the Genus database with same CATH superfamily
2FUSA 2JARA 2PTSA 3KDZA 4APBA 1T6JA 5EYTA 1XL8A 5F91A 3R6QA 2VD6A 3F4SA 1YFEA 3UNVA 1EB4A 1XMCA 5EYVA 1Z4LA 4HGVA 1TJUA 2O7BA 4IQJM 4ADLA 3CRVA 2D27A 4YIKA 4C5UA 4L6CA 1JSWA 4NSLA 2VSFA 4WNLA 4NFLA 1Z4IA 2I7DA 2O6YA 1Y2MA 2HVGA 3CRW1 2NYFA 1W27A 4ADMA 4YIHA 2JAOA 1Z4QA 2JAWA 4FLCA 3F4RA 1T6PA 2PTQA 1Z4PX 2J91A 1XLYA 4MX2A 2QVEA 5HW2A 1MH9A 2X75A 1FURA 1GK3A 2QGAB 3BHGA 1FUQA 3GTDA 1B8FA 3RD8A 2E9FA 3NO9A 1AUWA 2FELA 1K7WA 1FUOA 3GZHA 5H8WA 2OHYA 1IW7D 1HY0A 1Q5NA 1YFMA 2PTRA 1TJWA 3R6VA 1YISA 4BAAA 3RRPA 1TJ7A 4FFXA 3C8TA 1I0AA 3U13A 1K62A 2O7DA 4MUMA 1Z4JA 3BWVA 4EEIA 3OCFA 3QBPA 4NLEA 1DCNA 2RJSA 1XL7A 3F4TA 4L6AA 1C3CA 1Z4MA 2YIIA 3CZOA 1Q91A 3OCEA 1C3UA 2O7EA 2O7FA 1U16A 1DOFA 2PFMA 1GK2A 4C6GA 2YV5A 3NZ4A 1U0LA 2RJRA 4V2QA 1J3UA 1FUPA 2FENA 2VL7A 3R6YA 1TJVA 3KDYA 2O78A 5D6BA 4EFCA 4C5SA 4APAA 1GKMA 1T9HA 3U19A 3TV2A 1XWOA 3CI0K 4A15A 4MWOA 1GKJA 5F92A 4C5RA 2D28C 4E88A 3E04A 5M0IA 5M0JA 4V2RA 1VDKA 4BABA 2JAUA 1KQ7A 2NYNA 4CQ5A 2RCNA 4L57A 1XMDA 1HY1A 1Z4KA 1U15A 1RE5A 1Q92A
chains in the Genus database with same CATH topology
2FUSA 2PTSA 3KDZA 4APBA 1T6JA 5EYTA 5F91A 3R6QA 2VD6A 1YFEA 3UNVA 1EB4A 5EYVA 4HGVA 1TJUA 2O7BA 4ADLA 4C5UA 1JSWA 4NSLA 2O6YA 1Y2MA 2HVGA 2NYFA 1W27A 4ADMA 4FLCA 1T6PA 2PTQA 2J91A 4MX2A 2QVEA 5HW2A 2X75A 1FURA 1GK3A 2QGAB 3BHGA 1FUQA 3GTDA 1B8FA 3RD8A 2E9FA 3NO9A 1AUWA 1K7WA 1FUOA 3GZHA 2OHYA 1HY0A 1YFMA 1Q5NA 2PTRA 1TJWA 3R6VA 1YISA 4BAAA 3RRPA 1TJ7A 4FFXA 3C8TA 1I0AA 1K62A 2O7DA 4EEIA 3OCFA 3QBPA 4NLEA 1DCNA 2RJSA 1C3CA 2YIIA 3CZOA 3OCEA 1C3UA 2O7EA 2O7FA 1U16A 1GK2A 1DOFA 2PFMA 4C6GA 3NZ4A 2RJRA 4V2QA 1J3UA 1FUPA 3R6YA 1TJVA 3KDYA 2O78A 5D6BA 4EFCA 4C5SA 4APAA 1GKMA 3TV2A 1XWOA 1GKJA 5F92A 4C5RA 3E04A 4V2RA 1VDKA 4BABA 2NYNA 1KQ7A 4CQ5A 1HY1A 1U15A 1RE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FUS A;  2PTS A;  3KDZ A;  4APB A;  1T6J A;  5EYT A;  5F91 A;  3R6Q A;  2VD6 A;  1YFE A;  3UNV A;  1EB4 A;  5EYV A;  4HGV A;  1TJU A;  2O7B A;  4ADL A;  4C5U A;  1JSW A;  4NSL A;  2O6Y A;  1Y2M A;  2HVG A;  2NYF A;  1W27 A;  4ADM A;  4FLC A;  1T6P A;  2PTQ A;  2J91 A;  4MX2 A;  2QVE A;  5HW2 A;  2X75 A;  1FUR A;  1GK3 A;  2QGA B;  3BHG A;  1FUQ A;  3GTD A;  1B8F A;  3RD8 A;  2E9F A;  3NO9 A;  1AUW A;  1K7W A;  1FUO A;  3GZH A;  2OHY A;  1HY0 A;  1YFM A;  1Q5N A;  2PTR A;  1TJW A;  3R6V A;  1YIS A;  4BAA A;  3RRP A;  1TJ7 A;  4FFX A;  3C8T A;  1I0A A;  1K62 A;  2O7D A;  4EEI A;  3OCF A;  3QBP A;  4NLE A;  1DCN A;  2RJS A;  1C3C A;  2YII A;  3CZO A;  3OCE A;  1C3U A;  2O7E A;  2O7F A;  1U16 A;  1GK2 A;  1DOF A;  2PFM A;  4C6G A;  3NZ4 A;  2RJR A;  4V2Q A;  1J3U A;  1FUP A;  3R6Y A;  1TJV A;  3KDY A;  2O78 A;  5D6B A;  4EFC A;  4C5S A;  4APA A;  1GKM A;  3TV2 A;  1XWO A;  1GKJ A;  5F92 A;  4C5R A;  3E04 A;  4V2R A;  1VDK A;  4BAB A;  2NYN A;  1KQ7 A;  4CQ5 A;  1HY1 A;  1U15 A;  1RE5 A; 
#chains in the Genus database with same CATH topology
 2FUS A;  2JAR A;  2PTS A;  3KDZ A;  4APB A;  1T6J A;  5EYT A;  1XL8 A;  5F91 A;  3R6Q A;  2VD6 A;  3F4S A;  1YFE A;  3UNV A;  1EB4 A;  1XMC A;  5EYV A;  1Z4L A;  4HGV A;  1TJU A;  2O7B A;  4IQJ M;  4ADL A;  3CRV A;  2D27 A;  4YIK A;  4C5U A;  4L6C A;  1JSW A;  4NSL A;  2VSF A;  4WNL A;  4NFL A;  1Z4I A;  2I7D A;  2O6Y A;  1Y2M A;  2HVG A;  3CRW 1;  2NYF A;  1W27 A;  4ADM A;  4YIH A;  2JAO A;  1Z4Q A;  2JAW A;  4FLC A;  3F4R A;  1T6P A;  2PTQ A;  1Z4P X;  2J91 A;  1XLY A;  4MX2 A;  2QVE A;  5HW2 A;  1MH9 A;  2X75 A;  1FUR A;  1GK3 A;  2QGA B;  3BHG A;  1FUQ A;  3GTD A;  1B8F A;  3RD8 A;  2E9F A;  3NO9 A;  1AUW A;  2FEL A;  1K7W A;  1FUO A;  3GZH A;  5H8W A;  2OHY A;  1IW7 D;  1HY0 A;  1Q5N A;  1YFM A;  2PTR A;  1TJW A;  3R6V A;  1YIS A;  4BAA A;  3RRP A;  1TJ7 A;  4FFX A;  3C8T A;  1I0A A;  3U13 A;  1K62 A;  2O7D A;  4MUM A;  1Z4J A;  3BWV A;  4EEI A;  3OCF A;  3QBP A;  4NLE A;  1DCN A;  2RJS A;  1XL7 A;  3F4T A;  4L6A A;  1C3C A;  1Z4M A;  2YII A;  3CZO A;  1Q91 A;  3OCE A;  1C3U A;  2O7E A;  2O7F A;  1U16 A;  1DOF A;  2PFM A;  1GK2 A;  4C6G A;  2YV5 A;  3NZ4 A;  1U0L A;  2RJR A;  4V2Q A;  1J3U A;  1FUP A;  2FEN A;  2VL7 A;  3R6Y A;  1TJV A;  3KDY A;  2O78 A;  5D6B A;  4EFC A;  4C5S A;  4APA A;  1GKM A;  1T9H A;  3U19 A;  3TV2 A;  1XWO A;  3CI0 K;  4A15 A;  4MWO A;  1GKJ A;  5F92 A;  4C5R A;  2D28 C;  4E88 A;  3E04 A;  5M0I A;  5M0J A;  4V2R A;  1VDK A;  4BAB A;  2JAU A;  1KQ7 A;  2NYN A;  4CQ5 A;  2RCN A;  4L57 A;  1XMD A;  1HY1 A;  1Z4K A;  1U15 A;  1RE5 A;  1Q92 A; 
#chains in the Genus database with same CATH homology
 2FUS A;  2PTS A;  3KDZ A;  4APB A;  1T6J A;  5EYT A;  5F91 A;  3R6Q A;  2VD6 A;  1YFE A;  3UNV A;  1EB4 A;  5EYV A;  4HGV A;  1TJU A;  2O7B A;  4ADL A;  4C5U A;  1JSW A;  4NSL A;  2O6Y A;  1Y2M A;  2HVG A;  2NYF A;  1W27 A;  4ADM A;  4FLC A;  1T6P A;  2PTQ A;  2J91 A;  4MX2 A;  2QVE A;  5HW2 A;  2X75 A;  1FUR A;  1GK3 A;  2QGA B;  3BHG A;  1FUQ A;  3GTD A;  1B8F A;  3RD8 A;  2E9F A;  3NO9 A;  1AUW A;  1K7W A;  1FUO A;  3GZH A;  2OHY A;  1HY0 A;  1YFM A;  1Q5N A;  2PTR A;  1TJW A;  3R6V A;  1YIS A;  4BAA A;  3RRP A;  1TJ7 A;  4FFX A;  3C8T A;  1I0A A;  1K62 A;  2O7D A;  4EEI A;  3OCF A;  3QBP A;  4NLE A;  1DCN A;  2RJS A;  1C3C A;  2YII A;  3CZO A;  3OCE A;  1C3U A;  2O7E A;  2O7F A;  1U16 A;  1GK2 A;  1DOF A;  2PFM A;  4C6G A;  3NZ4 A;  2RJR A;  4V2Q A;  1J3U A;  1FUP A;  3R6Y A;  1TJV A;  3KDY A;  2O78 A;  5D6B A;  4EFC A;  4C5S A;  4APA A;  1GKM A;  3TV2 A;  1XWO A;  1GKJ A;  5F92 A;  4C5R A;  3E04 A;  4V2R A;  1VDK A;  4BAB A;  2NYN A;  1KQ7 A;  4CQ5 A;  1HY1 A;  1U15 A;  1RE5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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