1FUOA

Fumarase c with bound citrate
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
456
structure length
456
Chain Sequence
VRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Lyase
molecule keywords FUMARASE C
total genus 175
structure length 456
sequence length 456
chains with identical sequence B
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1996-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1fuoA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1fuoA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1fuoA02
5EYVA 1GKMA 2FUSA 2RJSA 4C5UA 1VDKA 1C3CA 1Y2MA 4ADLA 2NYFA 3RD8A 1T6JA 5D6BA 1GK2A 2PTQA 5HW2A 2X75A 4ADMA 1FUPA 1FUQA 1I0AA 3UNVA 1AUWA 1T6PA 5EYTA 3GZHA 4NLEA 3E04A 4FLCA 4C5RA 3NO9A 2VD6A 1EB4A 1RE5A 1YFEA 1W27A 1FUOA 2O6YA 1K7WA 1TJUA 3R6VA 4FFXA 1C3UA 2PTRA 2QGAB 3GTDA 1DCNA 1DOFA 2RJRA 4MX2A 1TJWA 1B8FA 3C8TA 1HY0A 2YIIA 2QVEA 2O78A 3R6QA 1TJ7A 1TJVA 3OCEA 3KDYA 4APBA 1JSWA 3TV2A 1FURA 2O7FA 5F91A 2J91A 2HVGA 4V2QA 1J3UA 2E9FA 1KQ7A 1Q5NA 1XWOA 4EFCA 1HY1A 3QBPA 4C5SA 4CQ5A 2O7EA 1K62A 4EEIA 3RRPA 2O7DA 3NZ4A 4V2RA 2NYNA 1U16A 4BAAA 4APAA 2PTSA 1YFMA 5F92A 1GKJA 1U15A 3R6YA 4NSLA 3OCFA 1YISA 4C6GA 2O7BA 2OHYA 2PFMA 4BABA 3CZOA 3BHGA 1GK3A 3KDZA 4HGVA
chains in the Genus database with same CATH superfamily
5EYVA 1XLYA 1GKMA 2JAWA 2FENA 2FUSA 2RJSA 4C5UA 1VDKA 1C3CA 3F4SA 1Y2MA 1Z4JA 4NFLA 4ADLA 4E88A 3RD8A 2NYFA 1XMDA 1XL8A 1T6JA 2VL7A 5D6BA 3U19A 1GK2A 2D27A 1XMCA 2VSFA 2PTQA 5HW2A 2X75A 2RCNA 1Z4QA 4ADMA 1FUPA 1FUQA 1I0AA 3UNVA 4IQJM 1U0LA 1Z4IA 1AUWA 1T6PA 3CI0K 5EYTA 3GZHA 4NLEA 3E04A 4A15A 4FLCA 4C5RA 3NO9A 2VD6A 1EB4A 4MWOA 4L57A 1RE5A 1YFEA 1W27A 1FUOA 3U13A 2FELA 2O6YA 1K7WA 1TJUA 3R6VA 1Z4LA 4FFXA 5H8WA 1C3UA 2PTRA 2QGAB 3GTDA 3F4TA 1MH9A 1DCNA 1DOFA 2RJRA 4L6CA 1Q92A 3F4RA 4MX2A 1TJWA 1B8FA 3C8TA 1Z4PX 2YV5A 1HY0A 1XL7A 5M0JA 2YIIA 1Q91A 2QVEA 2O78A 4WNLA 3R6QA 1TJ7A 1TJVA 3CRW1 4YIHA 3OCEA 2JAOA 4MUMA 3KDYA 4APBA 1JSWA 3TV2A 1FURA 2O7FA 5F91A 2J91A 2HVGA 4V2QA 1J3UA 1IW7D 2JAUA 2E9FA 1KQ7A 1Q5NA 1XWOA 4L6AA 1HY1A 4EFCA 2I7DA 3QBPA 4C5SA 3BWVA 4CQ5A 2O7EA 1K62A 4EEIA 1Z4KA 4YIKA 3RRPA 2O7DA 3NZ4A 4V2RA 2NYNA 1U16A 1T9HA 2D28C 4BAAA 4APAA 2PTSA 1YFMA 5F92A 3CRVA 1GKJA 1U15A 3R6YA 5M0IA 4NSLA 3OCFA 1YISA 4C6GA 2O7BA 2OHYA 2PFMA 4BABA 3CZOA 3BHGA 1Z4MA 1GK3A 3KDZA 4HGVA 2JARA
chains in the Genus database with same CATH topology
5EYVA 1GKMA 2FUSA 2RJSA 4C5UA 1VDKA 1C3CA 1Y2MA 4ADLA 2NYFA 3RD8A 1T6JA 5D6BA 1GK2A 2PTQA 5HW2A 2X75A 4ADMA 1FUPA 1FUQA 1I0AA 3UNVA 1AUWA 1T6PA 5EYTA 3GZHA 4NLEA 3E04A 4FLCA 4C5RA 3NO9A 2VD6A 1EB4A 1RE5A 1YFEA 1W27A 1FUOA 2O6YA 1K7WA 1TJUA 3R6VA 4FFXA 1C3UA 2PTRA 2QGAB 3GTDA 1DCNA 1DOFA 2RJRA 4MX2A 1TJWA 1B8FA 3C8TA 1HY0A 2YIIA 2QVEA 2O78A 3R6QA 1TJ7A 1TJVA 3OCEA 3KDYA 4APBA 1JSWA 3TV2A 1FURA 2O7FA 5F91A 2J91A 2HVGA 4V2QA 1J3UA 2E9FA 1KQ7A 1Q5NA 1XWOA 4EFCA 1HY1A 3QBPA 4C5SA 4CQ5A 2O7EA 1K62A 4EEIA 3RRPA 2O7DA 3NZ4A 4V2RA 2NYNA 1U16A 4BAAA 4APAA 2PTSA 1YFMA 5F92A 1GKJA 1U15A 3R6YA 4NSLA 3OCFA 1YISA 4C6GA 2O7BA 2OHYA 2PFMA 4BABA 3CZOA 3BHGA 1GK3A 3KDZA 4HGVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EYV A;  1GKM A;  2FUS A;  2RJS A;  4C5U A;  1VDK A;  1C3C A;  1Y2M A;  4ADL A;  2NYF A;  3RD8 A;  1T6J A;  5D6B A;  1GK2 A;  2PTQ A;  5HW2 A;  2X75 A;  4ADM A;  1FUP A;  1FUQ A;  1I0A A;  3UNV A;  1AUW A;  1T6P A;  5EYT A;  3GZH A;  4NLE A;  3E04 A;  4FLC A;  4C5R A;  3NO9 A;  2VD6 A;  1EB4 A;  1RE5 A;  1YFE A;  1W27 A;  1FUO A;  2O6Y A;  1K7W A;  1TJU A;  3R6V A;  4FFX A;  1C3U A;  2PTR A;  2QGA B;  3GTD A;  1DCN A;  1DOF A;  2RJR A;  4MX2 A;  1TJW A;  1B8F A;  3C8T A;  1HY0 A;  2YII A;  2QVE A;  2O78 A;  3R6Q A;  1TJ7 A;  1TJV A;  3OCE A;  3KDY A;  4APB A;  1JSW A;  3TV2 A;  1FUR A;  2O7F A;  5F91 A;  2J91 A;  2HVG A;  4V2Q A;  1J3U A;  2E9F A;  1KQ7 A;  1Q5N A;  1XWO A;  4EFC A;  1HY1 A;  3QBP A;  4C5S A;  4CQ5 A;  2O7E A;  1K62 A;  4EEI A;  3RRP A;  2O7D A;  3NZ4 A;  4V2R A;  2NYN A;  1U16 A;  4BAA A;  4APA A;  2PTS A;  1YFM A;  5F92 A;  1GKJ A;  1U15 A;  3R6Y A;  4NSL A;  3OCF A;  1YIS A;  4C6G A;  2O7B A;  2OHY A;  2PFM A;  4BAB A;  3CZO A;  3BHG A;  1GK3 A;  3KDZ A;  4HGV A; 
#chains in the Genus database with same CATH topology
 5EYV A;  1XLY A;  1GKM A;  2JAW A;  2FEN A;  2FUS A;  2RJS A;  4C5U A;  1VDK A;  1C3C A;  3F4S A;  1Y2M A;  1Z4J A;  4NFL A;  4ADL A;  4E88 A;  3RD8 A;  2NYF A;  1XMD A;  1XL8 A;  1T6J A;  2VL7 A;  5D6B A;  3U19 A;  1GK2 A;  2D27 A;  1XMC A;  2VSF A;  2PTQ A;  5HW2 A;  2X75 A;  2RCN A;  1Z4Q A;  4ADM A;  1FUP A;  1FUQ A;  1I0A A;  3UNV A;  4IQJ M;  1U0L A;  1Z4I A;  1AUW A;  1T6P A;  3CI0 K;  5EYT A;  3GZH A;  4NLE A;  3E04 A;  4A15 A;  4FLC A;  4C5R A;  3NO9 A;  2VD6 A;  1EB4 A;  4MWO A;  4L57 A;  1RE5 A;  1YFE A;  1W27 A;  1FUO A;  3U13 A;  2FEL A;  2O6Y A;  1K7W A;  1TJU A;  3R6V A;  1Z4L A;  4FFX A;  5H8W A;  1C3U A;  2PTR A;  2QGA B;  3GTD A;  3F4T A;  1MH9 A;  1DCN A;  1DOF A;  2RJR A;  4L6C A;  1Q92 A;  3F4R A;  4MX2 A;  1TJW A;  1B8F A;  3C8T A;  1Z4P X;  2YV5 A;  1HY0 A;  1XL7 A;  5M0J A;  2YII A;  1Q91 A;  2QVE A;  2O78 A;  4WNL A;  3R6Q A;  1TJ7 A;  1TJV A;  3CRW 1;  4YIH A;  3OCE A;  2JAO A;  4MUM A;  3KDY A;  4APB A;  1JSW A;  3TV2 A;  1FUR A;  2O7F A;  5F91 A;  2J91 A;  2HVG A;  4V2Q A;  1J3U A;  1IW7 D;  2JAU A;  2E9F A;  1KQ7 A;  1Q5N A;  1XWO A;  4L6A A;  1HY1 A;  4EFC A;  2I7D A;  3QBP A;  4C5S A;  3BWV A;  4CQ5 A;  2O7E A;  1K62 A;  4EEI A;  1Z4K A;  4YIK A;  3RRP A;  2O7D A;  3NZ4 A;  4V2R A;  2NYN A;  1U16 A;  1T9H A;  2D28 C;  4BAA A;  4APA A;  2PTS A;  1YFM A;  5F92 A;  3CRV A;  1GKJ A;  1U15 A;  3R6Y A;  5M0I A;  4NSL A;  3OCF A;  1YIS A;  4C6G A;  2O7B A;  2OHY A;  2PFM A;  4BAB A;  3CZO A;  3BHG A;  1Z4M A;  1GK3 A;  3KDZ A;  4HGV A;  2JAR A; 
#chains in the Genus database with same CATH homology
 5EYV A;  1GKM A;  2FUS A;  2RJS A;  4C5U A;  1VDK A;  1C3C A;  1Y2M A;  4ADL A;  2NYF A;  3RD8 A;  1T6J A;  5D6B A;  1GK2 A;  2PTQ A;  5HW2 A;  2X75 A;  4ADM A;  1FUP A;  1FUQ A;  1I0A A;  3UNV A;  1AUW A;  1T6P A;  5EYT A;  3GZH A;  4NLE A;  3E04 A;  4FLC A;  4C5R A;  3NO9 A;  2VD6 A;  1EB4 A;  1RE5 A;  1YFE A;  1W27 A;  1FUO A;  2O6Y A;  1K7W A;  1TJU A;  3R6V A;  4FFX A;  1C3U A;  2PTR A;  2QGA B;  3GTD A;  1DCN A;  1DOF A;  2RJR A;  4MX2 A;  1TJW A;  1B8F A;  3C8T A;  1HY0 A;  2YII A;  2QVE A;  2O78 A;  3R6Q A;  1TJ7 A;  1TJV A;  3OCE A;  3KDY A;  4APB A;  1JSW A;  3TV2 A;  1FUR A;  2O7F A;  5F91 A;  2J91 A;  2HVG A;  4V2Q A;  1J3U A;  2E9F A;  1KQ7 A;  1Q5N A;  1XWO A;  4EFC A;  1HY1 A;  3QBP A;  4C5S A;  4CQ5 A;  2O7E A;  1K62 A;  4EEI A;  3RRP A;  2O7D A;  3NZ4 A;  4V2R A;  2NYN A;  1U16 A;  4BAA A;  4APA A;  2PTS A;  1YFM A;  5F92 A;  1GKJ A;  1U15 A;  3R6Y A;  4NSL A;  3OCF A;  1YIS A;  4C6G A;  2O7B A;  2OHY A;  2PFM A;  4BAB A;  3CZO A;  3BHG A;  1GK3 A;  3KDZ A;  4HGV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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