3TV2A

Structure of a class ii fumarate hydratase from burkholderia pseudomallei
Total Genus 178
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
457
structure length
457
Chain Sequence
RMERDTFGEIAVPAARLWGAQTQRSLQNFKISTEKQSPELIHALALIKRAAAAVNLELGVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGERGESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIVKIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKFAAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGPRCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFRPMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAAQIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Lyase
molecule keywords Fumarate hydratase, class II
publication title Structure of a class II fumarate hydratase from Burkholderia pseudomallei
rcsb
source organism Burkholderia pseudomallei
total genus 178
structure length 457
sequence length 457
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2011-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3tv2A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3tv2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3tv2A02
1Y2MA 3OCEA 3BHGA 1DOFA 3KDYA 2X75A 2PTRA 3R6YA 1U16A 4APAA 1JSWA 1W27A 2QGAB 3C8TA 2NYFA 4NLEA 4CQ5A 1XWOA 4ADMA 1T6PA 3GZHA 2PTQA 1DCNA 1TJVA 4EFCA 1TJWA 4FLCA 2HVGA 1HY1A 3E04A 2VD6A 4C6GA 3QBPA 1T6JA 1K7WA 2PTSA 1FUQA 4C5RA 1C3CA 4BABA 1HY0A 1TJUA 2O7FA 2O7DA 4FFXA 4C5SA 1B8FA 1YFEA 4MX2A 4APBA 2YIIA 4V2QA 3RRPA 4ADLA 1YISA 5HW2A 2OHYA 3GTDA 3TV2A 3OCFA 1GKJA 2FUSA 4C5UA 1TJ7A 1GKMA 1Q5NA 1AUWA 2NYNA 1FUPA 2J91A 5EYVA 3CZOA 1GK3A 2QVEA 2RJRA 4EEIA 3NO9A 2O7BA 1FUOA 1K62A 4HGVA 1U15A 5F92A 1VDKA 2O7EA 1RE5A 1I0AA 3UNVA 3R6QA 1YFMA 5D6BA 3NZ4A 4BAAA 1J3UA 1C3UA 1GK2A 4V2RA 2O78A 5EYTA 2E9FA 1KQ7A 3KDZA 2RJSA 1EB4A 5F91A 4NSLA 2PFMA 1FURA 2O6YA 3R6VA 3RD8A
chains in the Genus database with same CATH superfamily
5M0IA 1Y2MA 3OCEA 3BHGA 3F4TA 1DOFA 1Z4QA 3KDYA 2X75A 2PTRA 3R6YA 1U16A 4APAA 1JSWA 1W27A 2QGAB 3C8TA 3U13A 1Z4KA 2NYFA 4NLEA 2VSFA 1XLYA 4WNLA 4L57A 4IQJM 4CQ5A 1XWOA 4ADMA 1T6PA 3GZHA 2PTQA 1DCNA 1TJVA 4EFCA 1TJWA 4FLCA 2HVGA 3F4SA 1HY1A 3E04A 3CRVA 2VD6A 1XL8A 2FENA 1Z4LA 4C6GA 1MH9A 1Z4IA 4E88A 3QBPA 2JAOA 1K7WA 1T6JA 2PTSA 1FUQA 4C5RA 1C3CA 4BABA 1Z4MA 1HY0A 1TJUA 2JAWA 2O7FA 2O7DA 4L6CA 4FFXA 4C5SA 1B8FA 4L6AA 4A15A 1YFEA 1XMCA 4MX2A 4APBA 2YIIA 4V2QA 3RRPA 4ADLA 4YIHA 2FELA 3U19A 1YISA 4NFLA 4YIKA 5HW2A 1XL7A 2OHYA 3BWVA 3GTDA 3TV2A 3OCFA 1GKJA 2FUSA 1Q92A 4C5UA 1TJ7A 1GKMA 2JAUA 1Q5NA 1AUWA 2NYNA 1FUPA 2J91A 5EYVA 3CZOA 1GK3A 2QVEA 2RJRA 5M0JA 4EEIA 3NO9A 2O7BA 1FUOA 1K62A 4HGVA 1Q91A 5H8WA 1T9HA 1U15A 3CRW1 2D27A 2YV5A 1VDKA 5F92A 1RE5A 1I0AA 2O7EA 3UNVA 1Z4PX 3R6QA 1YFMA 2RCNA 5D6BA 3NZ4A 4BAAA 2VL7A 1J3UA 1C3UA 1U0LA 2D28C 1GK2A 3F4RA 2I7DA 2JARA 4V2RA 3CI0K 2O78A 5EYTA 1XMDA 2E9FA 1KQ7A 1IW7D 4MUMA 3KDZA 2RJSA 1Z4JA 1EB4A 5F91A 4MWOA 2PFMA 4NSLA 1FURA 2O6YA 3R6VA 3RD8A
chains in the Genus database with same CATH topology
1Y2MA 3OCEA 3BHGA 1DOFA 3KDYA 2X75A 2PTRA 3R6YA 1U16A 4APAA 1JSWA 1W27A 2QGAB 3C8TA 2NYFA 4NLEA 4CQ5A 1XWOA 4ADMA 1T6PA 3GZHA 2PTQA 1DCNA 1TJVA 4EFCA 1TJWA 4FLCA 2HVGA 1HY1A 3E04A 2VD6A 4C6GA 3QBPA 1T6JA 1K7WA 2PTSA 1FUQA 4C5RA 1C3CA 4BABA 1HY0A 1TJUA 2O7FA 2O7DA 4FFXA 4C5SA 1B8FA 1YFEA 4MX2A 4APBA 2YIIA 4V2QA 3RRPA 4ADLA 1YISA 5HW2A 2OHYA 3GTDA 3TV2A 3OCFA 1GKJA 2FUSA 4C5UA 1TJ7A 1GKMA 1Q5NA 1AUWA 2NYNA 1FUPA 2J91A 5EYVA 3CZOA 1GK3A 2QVEA 2RJRA 4EEIA 3NO9A 2O7BA 1FUOA 1K62A 4HGVA 1U15A 5F92A 1VDKA 2O7EA 1RE5A 1I0AA 3UNVA 3R6QA 1YFMA 5D6BA 3NZ4A 4BAAA 1J3UA 1C3UA 1GK2A 4V2RA 2O78A 5EYTA 2E9FA 1KQ7A 3KDZA 2RJSA 1EB4A 5F91A 4NSLA 2PFMA 1FURA 2O6YA 3R6VA 3RD8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y2M A;  3OCE A;  3BHG A;  1DOF A;  3KDY A;  2X75 A;  2PTR A;  3R6Y A;  1U16 A;  4APA A;  1JSW A;  1W27 A;  2QGA B;  3C8T A;  2NYF A;  4NLE A;  4CQ5 A;  1XWO A;  4ADM A;  1T6P A;  3GZH A;  2PTQ A;  1DCN A;  1TJV A;  4EFC A;  1TJW A;  4FLC A;  2HVG A;  1HY1 A;  3E04 A;  2VD6 A;  4C6G A;  3QBP A;  1T6J A;  1K7W A;  2PTS A;  1FUQ A;  4C5R A;  1C3C A;  4BAB A;  1HY0 A;  1TJU A;  2O7F A;  2O7D A;  4FFX A;  4C5S A;  1B8F A;  1YFE A;  4MX2 A;  4APB A;  2YII A;  4V2Q A;  3RRP A;  4ADL A;  1YIS A;  5HW2 A;  2OHY A;  3GTD A;  3TV2 A;  3OCF A;  1GKJ A;  2FUS A;  4C5U A;  1TJ7 A;  1GKM A;  1Q5N A;  1AUW A;  2NYN A;  1FUP A;  2J91 A;  5EYV A;  3CZO A;  1GK3 A;  2QVE A;  2RJR A;  4EEI A;  3NO9 A;  2O7B A;  1FUO A;  1K62 A;  4HGV A;  1U15 A;  5F92 A;  1VDK A;  2O7E A;  1RE5 A;  1I0A A;  3UNV A;  3R6Q A;  1YFM A;  5D6B A;  3NZ4 A;  4BAA A;  1J3U A;  1C3U A;  1GK2 A;  4V2R A;  2O78 A;  5EYT A;  2E9F A;  1KQ7 A;  3KDZ A;  2RJS A;  1EB4 A;  5F91 A;  4NSL A;  2PFM A;  1FUR A;  2O6Y A;  3R6V A;  3RD8 A; 
#chains in the Genus database with same CATH topology
 5M0I A;  1Y2M A;  3OCE A;  3BHG A;  3F4T A;  1DOF A;  1Z4Q A;  3KDY A;  2X75 A;  2PTR A;  3R6Y A;  1U16 A;  4APA A;  1JSW A;  1W27 A;  2QGA B;  3C8T A;  3U13 A;  1Z4K A;  2NYF A;  4NLE A;  2VSF A;  1XLY A;  4WNL A;  4L57 A;  4IQJ M;  4CQ5 A;  1XWO A;  4ADM A;  1T6P A;  3GZH A;  2PTQ A;  1DCN A;  1TJV A;  4EFC A;  1TJW A;  4FLC A;  2HVG A;  3F4S A;  1HY1 A;  3E04 A;  3CRV A;  2VD6 A;  1XL8 A;  2FEN A;  1Z4L A;  4C6G A;  1MH9 A;  1Z4I A;  4E88 A;  3QBP A;  2JAO A;  1K7W A;  1T6J A;  2PTS A;  1FUQ A;  4C5R A;  1C3C A;  4BAB A;  1Z4M A;  1HY0 A;  1TJU A;  2JAW A;  2O7F A;  2O7D A;  4L6C A;  4FFX A;  4C5S A;  1B8F A;  4L6A A;  4A15 A;  1YFE A;  1XMC A;  4MX2 A;  4APB A;  2YII A;  4V2Q A;  3RRP A;  4ADL A;  4YIH A;  2FEL A;  3U19 A;  1YIS A;  4NFL A;  4YIK A;  5HW2 A;  1XL7 A;  2OHY A;  3BWV A;  3GTD A;  3TV2 A;  3OCF A;  1GKJ A;  2FUS A;  1Q92 A;  4C5U A;  1TJ7 A;  1GKM A;  2JAU A;  1Q5N A;  1AUW A;  2NYN A;  1FUP A;  2J91 A;  5EYV A;  3CZO A;  1GK3 A;  2QVE A;  2RJR A;  5M0J A;  4EEI A;  3NO9 A;  2O7B A;  1FUO A;  1K62 A;  4HGV A;  1Q91 A;  5H8W A;  1T9H A;  1U15 A;  3CRW 1;  2D27 A;  2YV5 A;  1VDK A;  5F92 A;  1RE5 A;  1I0A A;  2O7E A;  3UNV A;  1Z4P X;  3R6Q A;  1YFM A;  2RCN A;  5D6B A;  3NZ4 A;  4BAA A;  2VL7 A;  1J3U A;  1C3U A;  1U0L A;  2D28 C;  1GK2 A;  3F4R A;  2I7D A;  2JAR A;  4V2R A;  3CI0 K;  2O78 A;  5EYT A;  1XMD A;  2E9F A;  1KQ7 A;  1IW7 D;  4MUM A;  3KDZ A;  2RJS A;  1Z4J A;  1EB4 A;  5F91 A;  4MWO A;  2PFM A;  4NSL A;  1FUR A;  2O6Y A;  3R6V A;  3RD8 A; 
#chains in the Genus database with same CATH homology
 1Y2M A;  3OCE A;  3BHG A;  1DOF A;  3KDY A;  2X75 A;  2PTR A;  3R6Y A;  1U16 A;  4APA A;  1JSW A;  1W27 A;  2QGA B;  3C8T A;  2NYF A;  4NLE A;  4CQ5 A;  1XWO A;  4ADM A;  1T6P A;  3GZH A;  2PTQ A;  1DCN A;  1TJV A;  4EFC A;  1TJW A;  4FLC A;  2HVG A;  1HY1 A;  3E04 A;  2VD6 A;  4C6G A;  3QBP A;  1T6J A;  1K7W A;  2PTS A;  1FUQ A;  4C5R A;  1C3C A;  4BAB A;  1HY0 A;  1TJU A;  2O7F A;  2O7D A;  4FFX A;  4C5S A;  1B8F A;  1YFE A;  4MX2 A;  4APB A;  2YII A;  4V2Q A;  3RRP A;  4ADL A;  1YIS A;  5HW2 A;  2OHY A;  3GTD A;  3TV2 A;  3OCF A;  1GKJ A;  2FUS A;  4C5U A;  1TJ7 A;  1GKM A;  1Q5N A;  1AUW A;  2NYN A;  1FUP A;  2J91 A;  5EYV A;  3CZO A;  1GK3 A;  2QVE A;  2RJR A;  4EEI A;  3NO9 A;  2O7B A;  1FUO A;  1K62 A;  4HGV A;  1U15 A;  5F92 A;  1VDK A;  2O7E A;  1RE5 A;  1I0A A;  3UNV A;  3R6Q A;  1YFM A;  5D6B A;  3NZ4 A;  4BAA A;  1J3U A;  1C3U A;  1GK2 A;  4V2R A;  2O78 A;  5EYT A;  2E9F A;  1KQ7 A;  3KDZ A;  2RJS A;  1EB4 A;  5F91 A;  4NSL A;  2PFM A;  1FUR A;  2O6Y A;  3R6V A;  3RD8 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...