3TV2A

Structure of a class ii fumarate hydratase from burkholderia pseudomallei
Total Genus 178
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
457
structure length
457
Chain Sequence
b'RMERDTFGEIAVPAARLWGAQTQRSLQNFKISTEKQSPELIHALALIKRAAAAVNLELGVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGERGESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIVKIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKFAAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGPRCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFRPMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAAQIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Fumarate hydratase, class II
publication title Structure of a class II fumarate hydratase from Burkholderia pseudomallei
rcsb
source organism Burkholderia pseudomallei
molecule tags Lyase
total genus 178
structure length 457
sequence length 457
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2011-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3tv2A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3tv2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3tv2A02
3NZ4A 4C6GA 2QGAB 1I0AA 3CZOA 2PTSA 3OCFA 4APAA 1AUWA 1TJWA 1YFEA 5D6BA 1T6JA 3KDZA 4FLCA 1VDKA 4ADLA 1JSWA 3BHGA 4C5UA 1GK2A 2E9FA 5EYVA 2RJSA 2X75A 5F91A 1EB4A 4BAAA 1J3UA 2NYFA 1TJVA 3R6YA 2O6YA 4APBA 4NSLA 1T6PA 4ADMA 1C3UA 1YISA 3OCEA 3TV2A 3QBPA 3R6VA 4EEIA 1C3CA 1FUPA 2O7DA 3E04A 2NYNA 4EFCA 1TJ7A 1Y2MA 2O7FA 2J91A 2QVEA 1K62A 4HGVA 1FUOA 2YIIA 1DOFA 2VD6A 1TJUA 1FURA 3KDYA 2O7BA 2O78A 3RRPA 2PTRA 4BABA 1HY0A 1GKJA 4V2RA 4C5RA 1W27A 5HW2A 4C5SA 1U16A 3UNVA 1Q5NA 1HY1A 1KQ7A 3RD8A 3GZHA 2PTQA 4MX2A 1U15A 4FFXA 5F92A 1GKMA 2O7EA 1B8FA 3R6QA 1FUQA 1RE5A 2RJRA 1K7WA 4NLEA 3C8TA 1GK3A 4V2QA 5EYTA 1YFMA 1DCNA 2PFMA 2OHYA 2HVGA 2FUSA 4CQ5A 1XWOA 3NO9A 3GTDA
chains in the Genus database with same CATH superfamily
3NZ4A 4C6GA 2QGAB 1I0AA 1U0LA 2FELA 1MH9A 3CZOA 4NFLA 2PTSA 3OCFA 4APAA 1AUWA 1TJWA 1YFEA 1Z4QA 5D6BA 2JAUA 1T6JA 1Z4IA 3KDZA 4FLCA 1VDKA 4ADLA 1JSWA 3BHGA 3CRW1 4C5UA 4YIHA 3F4RA 1GK2A 2E9FA 5EYVA 2RJSA 4L6CA 4WNLA 2JAWA 2X75A 5F91A 1XLYA 1EB4A 4BAAA 1J3UA 2NYFA 1TJVA 3R6YA 2O6YA 4APBA 4NSLA 1T6PA 3F4TA 4ADMA 1C3UA 1YISA 3OCEA 3TV2A 3BWVA 3QBPA 2D28C 2RCNA 3R6VA 4EEIA 3U19A 1Z4JA 1C3CA 1FUPA 2O7DA 3E04A 2I7DA 4MUMA 2NYNA 4EFCA 1TJ7A 1Q91A 1Z4PX 1Y2MA 3F4SA 2O7FA 2J91A 4YIKA 2QVEA 1K62A 4HGVA 1FUOA 2YIIA 1DOFA 2VD6A 4IQJM 1TJUA 1FURA 3KDYA 1Z4LA 1Z4MA 2O7BA 2O78A 2JAOA 3RRPA 2PTRA 5M0IA 4BABA 2FENA 1HY0A 1GKJA 4A15A 4V2RA 1Q92A 4C5RA 1W27A 5HW2A 2D27A 1U16A 1XL8A 4C5SA 3CI0K 1XMCA 4MWOA 1T9HA 1XMDA 3UNVA 1Q5NA 4E88A 1HY1A 1KQ7A 3U13A 2VSFA 3RD8A 3GZHA 4L6AA 2PTQA 4MX2A 1U15A 4FFXA 2JARA 5F92A 1GKMA 2O7EA 1B8FA 4L57A 3CRVA 5M0JA 3R6QA 2VL7A 2YV5A 1FUQA 1RE5A 2RJRA 1IW7D 1K7WA 4NLEA 1XL7A 3C8TA 1GK3A 4V2QA 5EYTA 1YFMA 1DCNA 1Z4KA 2PFMA 2OHYA 2HVGA 2FUSA 4CQ5A 5H8WA 1XWOA 3NO9A 3GTDA
chains in the Genus database with same CATH topology
3NZ4A 4C6GA 2QGAB 1I0AA 3CZOA 2PTSA 3OCFA 4APAA 1AUWA 1TJWA 1YFEA 5D6BA 1T6JA 3KDZA 4FLCA 1VDKA 4ADLA 1JSWA 3BHGA 4C5UA 1GK2A 2E9FA 5EYVA 2RJSA 2X75A 5F91A 1EB4A 4BAAA 1J3UA 2NYFA 1TJVA 3R6YA 2O6YA 4APBA 4NSLA 1T6PA 4ADMA 1C3UA 1YISA 3OCEA 3TV2A 3QBPA 3R6VA 4EEIA 1C3CA 1FUPA 2O7DA 3E04A 2NYNA 4EFCA 1TJ7A 1Y2MA 2O7FA 2J91A 2QVEA 1K62A 4HGVA 1FUOA 2YIIA 1DOFA 2VD6A 1TJUA 1FURA 3KDYA 2O7BA 2O78A 3RRPA 2PTRA 4BABA 1HY0A 1GKJA 4V2RA 4C5RA 1W27A 5HW2A 4C5SA 1U16A 3UNVA 1Q5NA 1HY1A 1KQ7A 3RD8A 3GZHA 2PTQA 4MX2A 1U15A 4FFXA 5F92A 1GKMA 2O7EA 1B8FA 3R6QA 1FUQA 1RE5A 2RJRA 1K7WA 4NLEA 3C8TA 1GK3A 4V2QA 5EYTA 1YFMA 1DCNA 2PFMA 2OHYA 2HVGA 2FUSA 4CQ5A 1XWOA 3NO9A 3GTDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NZ4 A;  4C6G A;  2QGA B;  1I0A A;  3CZO A;  2PTS A;  3OCF A;  4APA A;  1AUW A;  1TJW A;  1YFE A;  5D6B A;  1T6J A;  3KDZ A;  4FLC A;  1VDK A;  4ADL A;  1JSW A;  3BHG A;  4C5U A;  1GK2 A;  2E9F A;  5EYV A;  2RJS A;  2X75 A;  5F91 A;  1EB4 A;  4BAA A;  1J3U A;  2NYF A;  1TJV A;  3R6Y A;  2O6Y A;  4APB A;  4NSL A;  1T6P A;  4ADM A;  1C3U A;  1YIS A;  3OCE A;  3TV2 A;  3QBP A;  3R6V A;  4EEI A;  1C3C A;  1FUP A;  2O7D A;  3E04 A;  2NYN A;  4EFC A;  1TJ7 A;  1Y2M A;  2O7F A;  2J91 A;  2QVE A;  1K62 A;  4HGV A;  1FUO A;  2YII A;  1DOF A;  2VD6 A;  1TJU A;  1FUR A;  3KDY A;  2O7B A;  2O78 A;  3RRP A;  2PTR A;  4BAB A;  1HY0 A;  1GKJ A;  4V2R A;  4C5R A;  1W27 A;  5HW2 A;  4C5S A;  1U16 A;  3UNV A;  1Q5N A;  1HY1 A;  1KQ7 A;  3RD8 A;  3GZH A;  2PTQ A;  4MX2 A;  1U15 A;  4FFX A;  5F92 A;  1GKM A;  2O7E A;  1B8F A;  3R6Q A;  1FUQ A;  1RE5 A;  2RJR A;  1K7W A;  4NLE A;  3C8T A;  1GK3 A;  4V2Q A;  5EYT A;  1YFM A;  1DCN A;  2PFM A;  2OHY A;  2HVG A;  2FUS A;  4CQ5 A;  1XWO A;  3NO9 A;  3GTD A; 
#chains in the Genus database with same CATH topology
 3NZ4 A;  4C6G A;  2QGA B;  1I0A A;  1U0L A;  2FEL A;  1MH9 A;  3CZO A;  4NFL A;  2PTS A;  3OCF A;  4APA A;  1AUW A;  1TJW A;  1YFE A;  1Z4Q A;  5D6B A;  2JAU A;  1T6J A;  1Z4I A;  3KDZ A;  4FLC A;  1VDK A;  4ADL A;  1JSW A;  3BHG A;  3CRW 1;  4C5U A;  4YIH A;  3F4R A;  1GK2 A;  2E9F A;  5EYV A;  2RJS A;  4L6C A;  4WNL A;  2JAW A;  2X75 A;  5F91 A;  1XLY A;  1EB4 A;  4BAA A;  1J3U A;  2NYF A;  1TJV A;  3R6Y A;  2O6Y A;  4APB A;  4NSL A;  1T6P A;  3F4T A;  4ADM A;  1C3U A;  1YIS A;  3OCE A;  3TV2 A;  3BWV A;  3QBP A;  2D28 C;  2RCN A;  3R6V A;  4EEI A;  3U19 A;  1Z4J A;  1C3C A;  1FUP A;  2O7D A;  3E04 A;  2I7D A;  4MUM A;  2NYN A;  4EFC A;  1TJ7 A;  1Q91 A;  1Z4P X;  1Y2M A;  3F4S A;  2O7F A;  2J91 A;  4YIK A;  2QVE A;  1K62 A;  4HGV A;  1FUO A;  2YII A;  1DOF A;  2VD6 A;  4IQJ M;  1TJU A;  1FUR A;  3KDY A;  1Z4L A;  1Z4M A;  2O7B A;  2O78 A;  2JAO A;  3RRP A;  2PTR A;  5M0I A;  4BAB A;  2FEN A;  1HY0 A;  1GKJ A;  4A15 A;  4V2R A;  1Q92 A;  4C5R A;  1W27 A;  5HW2 A;  2D27 A;  1U16 A;  1XL8 A;  4C5S A;  3CI0 K;  1XMC A;  4MWO A;  1T9H A;  1XMD A;  3UNV A;  1Q5N A;  4E88 A;  1HY1 A;  1KQ7 A;  3U13 A;  2VSF A;  3RD8 A;  3GZH A;  4L6A A;  2PTQ A;  4MX2 A;  1U15 A;  4FFX A;  2JAR A;  5F92 A;  1GKM A;  2O7E A;  1B8F A;  4L57 A;  3CRV A;  5M0J A;  3R6Q A;  2VL7 A;  2YV5 A;  1FUQ A;  1RE5 A;  2RJR A;  1IW7 D;  1K7W A;  4NLE A;  1XL7 A;  3C8T A;  1GK3 A;  4V2Q A;  5EYT A;  1YFM A;  1DCN A;  1Z4K A;  2PFM A;  2OHY A;  2HVG A;  2FUS A;  4CQ5 A;  5H8W A;  1XWO A;  3NO9 A;  3GTD A; 
#chains in the Genus database with same CATH homology
 3NZ4 A;  4C6G A;  2QGA B;  1I0A A;  3CZO A;  2PTS A;  3OCF A;  4APA A;  1AUW A;  1TJW A;  1YFE A;  5D6B A;  1T6J A;  3KDZ A;  4FLC A;  1VDK A;  4ADL A;  1JSW A;  3BHG A;  4C5U A;  1GK2 A;  2E9F A;  5EYV A;  2RJS A;  2X75 A;  5F91 A;  1EB4 A;  4BAA A;  1J3U A;  2NYF A;  1TJV A;  3R6Y A;  2O6Y A;  4APB A;  4NSL A;  1T6P A;  4ADM A;  1C3U A;  1YIS A;  3OCE A;  3TV2 A;  3QBP A;  3R6V A;  4EEI A;  1C3C A;  1FUP A;  2O7D A;  3E04 A;  2NYN A;  4EFC A;  1TJ7 A;  1Y2M A;  2O7F A;  2J91 A;  2QVE A;  1K62 A;  4HGV A;  1FUO A;  2YII A;  1DOF A;  2VD6 A;  1TJU A;  1FUR A;  3KDY A;  2O7B A;  2O78 A;  3RRP A;  2PTR A;  4BAB A;  1HY0 A;  1GKJ A;  4V2R A;  4C5R A;  1W27 A;  5HW2 A;  4C5S A;  1U16 A;  3UNV A;  1Q5N A;  1HY1 A;  1KQ7 A;  3RD8 A;  3GZH A;  2PTQ A;  4MX2 A;  1U15 A;  4FFX A;  5F92 A;  1GKM A;  2O7E A;  1B8F A;  3R6Q A;  1FUQ A;  1RE5 A;  2RJR A;  1K7W A;  4NLE A;  3C8T A;  1GK3 A;  4V2Q A;  5EYT A;  1YFM A;  1DCN A;  2PFM A;  2OHY A;  2HVG A;  2FUS A;  4CQ5 A;  1XWO A;  3NO9 A;  3GTD A; 
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similar chains in the Genus database (?% sequence similarity)
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