3TV2A

Structure of a class ii fumarate hydratase from burkholderia pseudomallei
Total Genus 178
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
457
structure length
457
Chain Sequence
RMERDTFGEIAVPAARLWGAQTQRSLQNFKISTEKQSPELIHALALIKRAAAAVNLELGVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGERGESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIVKIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKFAAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGPRCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFRPMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAAQIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Fumarate hydratase, class II
publication title Structure of a class II fumarate hydratase from Burkholderia pseudomallei
rcsb
source organism Burkholderia pseudomallei
molecule tags Lyase
total genus 178
structure length 457
sequence length 457
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2011-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3tv2A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3tv2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3tv2A02
5F92A 2PTQA 1C3UA 4APAA 1FUQA 1TJVA 4BAAA 1DOFA 2PTSA 1YFEA 4C5RA 1FUPA 3CZOA 2O7EA 1GK2A 3GTDA 3RD8A 2J91A 5D6BA 2RJRA 1T6PA 1EB4A 1HY1A 2OHYA 1YISA 1HY0A 4FFXA 1K62A 4APBA 2O78A 2VD6A 4CQ5A 1DCNA 3R6YA 3KDYA 1VDKA 4NLEA 1GKMA 1Q5NA 3QBPA 2O7BA 4EFCA 1FUOA 5HW2A 5F91A 1FURA 3TV2A 2O6YA 1J3UA 5EYVA 1I0AA 4C5SA 2NYNA 4NSLA 1TJUA 3GZHA 2QVEA 3R6QA 3RRPA 2PFMA 1XWOA 1RE5A 2O7FA 1U16A 1U15A 3OCFA 1KQ7A 2E9FA 1GK3A 3NZ4A 4BABA 4V2QA 3UNVA 2YIIA 2FUSA 1W27A 1B8FA 4FLCA 1TJWA 4ADLA 2PTRA 2X75A 1C3CA 2HVGA 5EYTA 1JSWA 2O7DA 1Y2MA 3E04A 3NO9A 2RJSA 1GKJA 4V2RA 3OCEA 4HGVA 4EEIA 3C8TA 3BHGA 1YFMA 1T6JA 1K7WA 2QGAB 1TJ7A 4MX2A 2NYFA 1AUWA 3R6VA 4C6GA 3KDZA 4C5UA 4ADMA
chains in the Genus database with same CATH superfamily
5F92A 2PTQA 1MH9A 1C3UA 4APAA 1FUQA 1TJVA 4BAAA 1DOFA 2PTSA 1YFEA 4C5RA 1FUPA 1U0LA 3CZOA 2O7EA 1GK2A 3GTDA 3RD8A 2J91A 5D6BA 2RJRA 4A15A 5H8WA 1T6PA 3CI0K 1EB4A 2JAWA 1Z4LA 1HY1A 2RCNA 2OHYA 1YISA 1HY0A 4FFXA 1K62A 4MUMA 3F4RA 4APBA 2O78A 2VD6A 3F4SA 4CQ5A 1XL8A 1DCNA 4E88A 3R6YA 3KDYA 2FELA 1VDKA 4NLEA 4IQJM 1GKMA 1Q5NA 3QBPA 2O7BA 4EFCA 2JAOA 1FUOA 5HW2A 5F91A 1FURA 3TV2A 4NFLA 2VSFA 2O6YA 1J3UA 5EYVA 1I0AA 1Z4KA 4C5SA 2NYNA 1XMDA 4NSLA 2D28C 1TJUA 2I7DA 3GZHA 1XLYA 2QVEA 3R6QA 3U19A 3RRPA 1XL7A 1Q91A 2PFMA 3BWVA 1XWOA 1IW7D 4L6CA 1RE5A 2O7FA 3CRVA 1U16A 3KDZA 1U15A 1Z4JA 1XMCA 2YV5A 1Z4PX 3OCFA 1KQ7A 2E9FA 1GK3A 3NZ4A 4BABA 4V2QA 3UNVA 2YIIA 2FUSA 1W27A 1B8FA 3CRW1 4FLCA 1TJWA 4ADLA 2D27A 4WNLA 2FENA 4MWOA 2PTRA 2X75A 1C3CA 2HVGA 5EYTA 1Z4QA 1JSWA 4YIKA 4L57A 1T9HA 2JARA 2O7DA 1Y2MA 1Z4MA 3E04A 5M0JA 3NO9A 2RJSA 3U13A 1GKJA 4V2RA 5M0IA 3OCEA 4HGVA 4EEIA 3C8TA 4L6AA 3BHGA 1YFMA 4YIHA 1T6JA 1K7WA 1Q92A 2QGAB 2VL7A 1TJ7A 3F4TA 4MX2A 2NYFA 1AUWA 2JAUA 3R6VA 4C6GA 1Z4IA 4C5UA 4ADMA
chains in the Genus database with same CATH topology
5F92A 2PTQA 1C3UA 4APAA 1FUQA 1TJVA 4BAAA 1DOFA 2PTSA 1YFEA 4C5RA 1FUPA 3CZOA 2O7EA 1GK2A 3GTDA 3RD8A 2J91A 5D6BA 2RJRA 1T6PA 1EB4A 1HY1A 2OHYA 1YISA 1HY0A 4FFXA 1K62A 4APBA 2O78A 2VD6A 4CQ5A 1DCNA 3R6YA 3KDYA 1VDKA 4NLEA 1GKMA 1Q5NA 3QBPA 2O7BA 4EFCA 1FUOA 5HW2A 5F91A 1FURA 3TV2A 2O6YA 1J3UA 5EYVA 1I0AA 4C5SA 2NYNA 4NSLA 1TJUA 3GZHA 2QVEA 3R6QA 3RRPA 2PFMA 1XWOA 1RE5A 2O7FA 1U16A 1U15A 3OCFA 1KQ7A 2E9FA 1GK3A 3NZ4A 4BABA 4V2QA 3UNVA 2YIIA 2FUSA 1W27A 1B8FA 4FLCA 1TJWA 4ADLA 2PTRA 2X75A 1C3CA 2HVGA 5EYTA 1JSWA 2O7DA 1Y2MA 3E04A 3NO9A 2RJSA 1GKJA 4V2RA 3OCEA 4HGVA 4EEIA 3C8TA 3BHGA 1YFMA 1T6JA 1K7WA 2QGAB 1TJ7A 4MX2A 2NYFA 1AUWA 3R6VA 4C6GA 3KDZA 4C5UA 4ADMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F92 A;  2PTQ A;  1C3U A;  4APA A;  1FUQ A;  1TJV A;  4BAA A;  1DOF A;  2PTS A;  1YFE A;  4C5R A;  1FUP A;  3CZO A;  2O7E A;  1GK2 A;  3GTD A;  3RD8 A;  2J91 A;  5D6B A;  2RJR A;  1T6P A;  1EB4 A;  1HY1 A;  2OHY A;  1YIS A;  1HY0 A;  4FFX A;  1K62 A;  4APB A;  2O78 A;  2VD6 A;  4CQ5 A;  1DCN A;  3R6Y A;  3KDY A;  1VDK A;  4NLE A;  1GKM A;  1Q5N A;  3QBP A;  2O7B A;  4EFC A;  1FUO A;  5HW2 A;  5F91 A;  1FUR A;  3TV2 A;  2O6Y A;  1J3U A;  5EYV A;  1I0A A;  4C5S A;  2NYN A;  4NSL A;  1TJU A;  3GZH A;  2QVE A;  3R6Q A;  3RRP A;  2PFM A;  1XWO A;  1RE5 A;  2O7F A;  1U16 A;  1U15 A;  3OCF A;  1KQ7 A;  2E9F A;  1GK3 A;  3NZ4 A;  4BAB A;  4V2Q A;  3UNV A;  2YII A;  2FUS A;  1W27 A;  1B8F A;  4FLC A;  1TJW A;  4ADL A;  2PTR A;  2X75 A;  1C3C A;  2HVG A;  5EYT A;  1JSW A;  2O7D A;  1Y2M A;  3E04 A;  3NO9 A;  2RJS A;  1GKJ A;  4V2R A;  3OCE A;  4HGV A;  4EEI A;  3C8T A;  3BHG A;  1YFM A;  1T6J A;  1K7W A;  2QGA B;  1TJ7 A;  4MX2 A;  2NYF A;  1AUW A;  3R6V A;  4C6G A;  3KDZ A;  4C5U A;  4ADM A; 
#chains in the Genus database with same CATH topology
 5F92 A;  2PTQ A;  1MH9 A;  1C3U A;  4APA A;  1FUQ A;  1TJV A;  4BAA A;  1DOF A;  2PTS A;  1YFE A;  4C5R A;  1FUP A;  1U0L A;  3CZO A;  2O7E A;  1GK2 A;  3GTD A;  3RD8 A;  2J91 A;  5D6B A;  2RJR A;  4A15 A;  5H8W A;  1T6P A;  3CI0 K;  1EB4 A;  2JAW A;  1Z4L A;  1HY1 A;  2RCN A;  2OHY A;  1YIS A;  1HY0 A;  4FFX A;  1K62 A;  4MUM A;  3F4R A;  4APB A;  2O78 A;  2VD6 A;  3F4S A;  4CQ5 A;  1XL8 A;  1DCN A;  4E88 A;  3R6Y A;  3KDY A;  2FEL A;  1VDK A;  4NLE A;  4IQJ M;  1GKM A;  1Q5N A;  3QBP A;  2O7B A;  4EFC A;  2JAO A;  1FUO A;  5HW2 A;  5F91 A;  1FUR A;  3TV2 A;  4NFL A;  2VSF A;  2O6Y A;  1J3U A;  5EYV A;  1I0A A;  1Z4K A;  4C5S A;  2NYN A;  1XMD A;  4NSL A;  2D28 C;  1TJU A;  2I7D A;  3GZH A;  1XLY A;  2QVE A;  3R6Q A;  3U19 A;  3RRP A;  1XL7 A;  1Q91 A;  2PFM A;  3BWV A;  1XWO A;  1IW7 D;  4L6C A;  1RE5 A;  2O7F A;  3CRV A;  1U16 A;  3KDZ A;  1U15 A;  1Z4J A;  1XMC A;  2YV5 A;  1Z4P X;  3OCF A;  1KQ7 A;  2E9F A;  1GK3 A;  3NZ4 A;  4BAB A;  4V2Q A;  3UNV A;  2YII A;  2FUS A;  1W27 A;  1B8F A;  3CRW 1;  4FLC A;  1TJW A;  4ADL A;  2D27 A;  4WNL A;  2FEN A;  4MWO A;  2PTR A;  2X75 A;  1C3C A;  2HVG A;  5EYT A;  1Z4Q A;  1JSW A;  4YIK A;  4L57 A;  1T9H A;  2JAR A;  2O7D A;  1Y2M A;  1Z4M A;  3E04 A;  5M0J A;  3NO9 A;  2RJS A;  3U13 A;  1GKJ A;  4V2R A;  5M0I A;  3OCE A;  4HGV A;  4EEI A;  3C8T A;  4L6A A;  3BHG A;  1YFM A;  4YIH A;  1T6J A;  1K7W A;  1Q92 A;  2QGA B;  2VL7 A;  1TJ7 A;  3F4T A;  4MX2 A;  2NYF A;  1AUW A;  2JAU A;  3R6V A;  4C6G A;  1Z4I A;  4C5U A;  4ADM A; 
#chains in the Genus database with same CATH homology
 5F92 A;  2PTQ A;  1C3U A;  4APA A;  1FUQ A;  1TJV A;  4BAA A;  1DOF A;  2PTS A;  1YFE A;  4C5R A;  1FUP A;  3CZO A;  2O7E A;  1GK2 A;  3GTD A;  3RD8 A;  2J91 A;  5D6B A;  2RJR A;  1T6P A;  1EB4 A;  1HY1 A;  2OHY A;  1YIS A;  1HY0 A;  4FFX A;  1K62 A;  4APB A;  2O78 A;  2VD6 A;  4CQ5 A;  1DCN A;  3R6Y A;  3KDY A;  1VDK A;  4NLE A;  1GKM A;  1Q5N A;  3QBP A;  2O7B A;  4EFC A;  1FUO A;  5HW2 A;  5F91 A;  1FUR A;  3TV2 A;  2O6Y A;  1J3U A;  5EYV A;  1I0A A;  4C5S A;  2NYN A;  4NSL A;  1TJU A;  3GZH A;  2QVE A;  3R6Q A;  3RRP A;  2PFM A;  1XWO A;  1RE5 A;  2O7F A;  1U16 A;  1U15 A;  3OCF A;  1KQ7 A;  2E9F A;  1GK3 A;  3NZ4 A;  4BAB A;  4V2Q A;  3UNV A;  2YII A;  2FUS A;  1W27 A;  1B8F A;  4FLC A;  1TJW A;  4ADL A;  2PTR A;  2X75 A;  1C3C A;  2HVG A;  5EYT A;  1JSW A;  2O7D A;  1Y2M A;  3E04 A;  3NO9 A;  2RJS A;  1GKJ A;  4V2R A;  3OCE A;  4HGV A;  4EEI A;  3C8T A;  3BHG A;  1YFM A;  1T6J A;  1K7W A;  2QGA B;  1TJ7 A;  4MX2 A;  2NYF A;  1AUW A;  3R6V A;  4C6G A;  3KDZ A;  4C5U A;  4ADM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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