4MX2A

Crystal structure of adenylosuccinate lyase from leishmania donovani
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
453
structure length
424
Chain Sequence
b'EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQITEEVRQELLAITPFTYVGYT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Crystal Structure of adenylosuccinate lyase from Leishmania donovani
rcsb
source organism Leishmania donovani
molecule tags Lyase
total genus 170
structure length 424
sequence length 453
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2013-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF08328 ASL_C Adenylosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4mx2A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4mx2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4mx2A02
1YFEA 3QBPA 1T6PA 4FFXA 1K7WA 3CZOA 4CQ5A 1DCNA 1DOFA 2O7DA 3UNVA 4APBA 4C5UA 3GTDA 4C5RA 3TV2A 1EB4A 2NYFA 4C6GA 3OCEA 1FUQA 2HVGA 2E9FA 1C3CA 1XWOA 3C8TA 4C5SA 4NLEA 1GK3A 1I0AA 4MX2A 3GZHA 1JSWA 1TJVA 1Y2MA 4BAAA 1AUWA 2PTSA 4V2QA 2YIIA 4HGVA 4ADMA 2O7BA 3KDYA 1T6JA 1GK2A 1U16A 1HY0A 2QGAB 1C3UA 2J91A 3OCFA 4EEIA 3KDZA 5HW2A 1TJUA 3NZ4A 4BABA 2FUSA 1YFMA 2VD6A 2PTQA 1FUOA 5EYVA 1GKMA 2O7FA 2O7EA 3R6VA 3RD8A 3RRPA 2NYNA 2RJRA 2X75A 2QVEA 4FLCA 1VDKA 1U15A 2O6YA 2PFMA 2OHYA 1Q5NA 4ADLA 3NO9A 1J3UA 4APAA 5D6BA 2PTRA 3R6YA 3E04A 4NSLA 3R6QA 2RJSA 4V2RA 1FUPA 3BHGA 1TJWA 5F91A 1B8FA 2O78A 5EYTA 1GKJA 4EFCA 1KQ7A 1FURA 1W27A 1K62A 1RE5A 1TJ7A 1YISA 5F92A 1HY1A
chains in the Genus database with same CATH superfamily
1YFEA 3QBPA 3F4RA 1T6PA 1Z4QA 2D27A 4FFXA 1K7WA 3CRW1 3CZOA 4CQ5A 1DCNA 1DOFA 2O7DA 2JAOA 3UNVA 1XLYA 4APBA 2I7DA 4YIHA 4C5UA 1Z4LA 3GTDA 4C5RA 3CI0K 3TV2A 1EB4A 2YV5A 2NYFA 4C6GA 1XMDA 1Z4JA 3OCEA 1FUQA 2HVGA 2E9FA 1C3CA 1XWOA 3C8TA 4C5SA 4NLEA 4L6AA 1GK3A 3F4SA 3F4TA 5M0JA 1I0AA 4MX2A 3GZHA 1JSWA 1TJVA 1Y2MA 4BAAA 2JAWA 1AUWA 2PTSA 1Z4MA 4V2QA 2JAUA 2YIIA 4HGVA 4ADMA 2O7BA 3KDYA 1T6JA 1U0LA 1GK2A 1U16A 1HY0A 2QGAB 1Z4KA 2RCNA 1C3UA 2J91A 2VL7A 1Z4IA 3OCFA 4EEIA 3KDZA 5HW2A 1TJUA 3NZ4A 4BABA 2FUSA 1XL8A 2JARA 1YFMA 2VD6A 2PTQA 1FUOA 5EYVA 4YIKA 1GKMA 4A15A 2O7FA 2O7EA 3BWVA 4MWOA 3R6VA 3RD8A 4IQJM 1XMCA 3RRPA 2NYNA 3CRVA 2RJRA 2X75A 2QVEA 4MUMA 4FLCA 4WNLA 1Q92A 1XL7A 1VDKA 1U15A 2FENA 2O6YA 2PFMA 2FELA 2OHYA 1Q5NA 4ADLA 1IW7D 3NO9A 1J3UA 4APAA 5D6BA 2PTRA 3R6YA 1Q91A 3E04A 4NSLA 3U19A 3R6QA 4L6CA 1T9HA 2VSFA 2RJSA 4V2RA 1FUPA 3BHGA 2D28C 1TJWA 4NFLA 5F91A 1B8FA 5M0IA 2O78A 5EYTA 1GKJA 4EFCA 1KQ7A 1FURA 1W27A 4L57A 1K62A 3U13A 1RE5A 4E88A 1TJ7A 1Z4PX 5H8WA 1YISA 1MH9A 5F92A 1HY1A
chains in the Genus database with same CATH topology
1YFEA 3QBPA 1T6PA 4FFXA 1K7WA 3CZOA 4CQ5A 1DCNA 1DOFA 2O7DA 3UNVA 4APBA 4C5UA 3GTDA 4C5RA 3TV2A 1EB4A 2NYFA 4C6GA 3OCEA 1FUQA 2HVGA 2E9FA 1C3CA 1XWOA 3C8TA 4C5SA 4NLEA 1GK3A 1I0AA 4MX2A 3GZHA 1JSWA 1TJVA 1Y2MA 4BAAA 1AUWA 2PTSA 4V2QA 2YIIA 4HGVA 4ADMA 2O7BA 3KDYA 1T6JA 1GK2A 1U16A 1HY0A 2QGAB 1C3UA 2J91A 3OCFA 4EEIA 3KDZA 5HW2A 1TJUA 3NZ4A 4BABA 2FUSA 1YFMA 2VD6A 2PTQA 1FUOA 5EYVA 1GKMA 2O7FA 2O7EA 3R6VA 3RD8A 3RRPA 2NYNA 2RJRA 2X75A 2QVEA 4FLCA 1VDKA 1U15A 2O6YA 2PFMA 2OHYA 1Q5NA 4ADLA 3NO9A 1J3UA 4APAA 5D6BA 2PTRA 3R6YA 3E04A 4NSLA 3R6QA 2RJSA 4V2RA 1FUPA 3BHGA 1TJWA 5F91A 1B8FA 2O78A 5EYTA 1GKJA 4EFCA 1KQ7A 1FURA 1W27A 1K62A 1RE5A 1TJ7A 1YISA 5F92A 1HY1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YFE A;  3QBP A;  1T6P A;  4FFX A;  1K7W A;  3CZO A;  4CQ5 A;  1DCN A;  1DOF A;  2O7D A;  3UNV A;  4APB A;  4C5U A;  3GTD A;  4C5R A;  3TV2 A;  1EB4 A;  2NYF A;  4C6G A;  3OCE A;  1FUQ A;  2HVG A;  2E9F A;  1C3C A;  1XWO A;  3C8T A;  4C5S A;  4NLE A;  1GK3 A;  1I0A A;  4MX2 A;  3GZH A;  1JSW A;  1TJV A;  1Y2M A;  4BAA A;  1AUW A;  2PTS A;  4V2Q A;  2YII A;  4HGV A;  4ADM A;  2O7B A;  3KDY A;  1T6J A;  1GK2 A;  1U16 A;  1HY0 A;  2QGA B;  1C3U A;  2J91 A;  3OCF A;  4EEI A;  3KDZ A;  5HW2 A;  1TJU A;  3NZ4 A;  4BAB A;  2FUS A;  1YFM A;  2VD6 A;  2PTQ A;  1FUO A;  5EYV A;  1GKM A;  2O7F A;  2O7E A;  3R6V A;  3RD8 A;  3RRP A;  2NYN A;  2RJR A;  2X75 A;  2QVE A;  4FLC A;  1VDK A;  1U15 A;  2O6Y A;  2PFM A;  2OHY A;  1Q5N A;  4ADL A;  3NO9 A;  1J3U A;  4APA A;  5D6B A;  2PTR A;  3R6Y A;  3E04 A;  4NSL A;  3R6Q A;  2RJS A;  4V2R A;  1FUP A;  3BHG A;  1TJW A;  5F91 A;  1B8F A;  2O78 A;  5EYT A;  1GKJ A;  4EFC A;  1KQ7 A;  1FUR A;  1W27 A;  1K62 A;  1RE5 A;  1TJ7 A;  1YIS A;  5F92 A;  1HY1 A; 
#chains in the Genus database with same CATH topology
 1YFE A;  3QBP A;  3F4R A;  1T6P A;  1Z4Q A;  2D27 A;  4FFX A;  1K7W A;  3CRW 1;  3CZO A;  4CQ5 A;  1DCN A;  1DOF A;  2O7D A;  2JAO A;  3UNV A;  1XLY A;  4APB A;  2I7D A;  4YIH A;  4C5U A;  1Z4L A;  3GTD A;  4C5R A;  3CI0 K;  3TV2 A;  1EB4 A;  2YV5 A;  2NYF A;  4C6G A;  1XMD A;  1Z4J A;  3OCE A;  1FUQ A;  2HVG A;  2E9F A;  1C3C A;  1XWO A;  3C8T A;  4C5S A;  4NLE A;  4L6A A;  1GK3 A;  3F4S A;  3F4T A;  5M0J A;  1I0A A;  4MX2 A;  3GZH A;  1JSW A;  1TJV A;  1Y2M A;  4BAA A;  2JAW A;  1AUW A;  2PTS A;  1Z4M A;  4V2Q A;  2JAU A;  2YII A;  4HGV A;  4ADM A;  2O7B A;  3KDY A;  1T6J A;  1U0L A;  1GK2 A;  1U16 A;  1HY0 A;  2QGA B;  1Z4K A;  2RCN A;  1C3U A;  2J91 A;  2VL7 A;  1Z4I A;  3OCF A;  4EEI A;  3KDZ A;  5HW2 A;  1TJU A;  3NZ4 A;  4BAB A;  2FUS A;  1XL8 A;  2JAR A;  1YFM A;  2VD6 A;  2PTQ A;  1FUO A;  5EYV A;  4YIK A;  1GKM A;  4A15 A;  2O7F A;  2O7E A;  3BWV A;  4MWO A;  3R6V A;  3RD8 A;  4IQJ M;  1XMC A;  3RRP A;  2NYN A;  3CRV A;  2RJR A;  2X75 A;  2QVE A;  4MUM A;  4FLC A;  4WNL A;  1Q92 A;  1XL7 A;  1VDK A;  1U15 A;  2FEN A;  2O6Y A;  2PFM A;  2FEL A;  2OHY A;  1Q5N A;  4ADL A;  1IW7 D;  3NO9 A;  1J3U A;  4APA A;  5D6B A;  2PTR A;  3R6Y A;  1Q91 A;  3E04 A;  4NSL A;  3U19 A;  3R6Q A;  4L6C A;  1T9H A;  2VSF A;  2RJS A;  4V2R A;  1FUP A;  3BHG A;  2D28 C;  1TJW A;  4NFL A;  5F91 A;  1B8F A;  5M0I A;  2O78 A;  5EYT A;  1GKJ A;  4EFC A;  1KQ7 A;  1FUR A;  1W27 A;  4L57 A;  1K62 A;  3U13 A;  1RE5 A;  4E88 A;  1TJ7 A;  1Z4P X;  5H8W A;  1YIS A;  1MH9 A;  5F92 A;  1HY1 A; 
#chains in the Genus database with same CATH homology
 1YFE A;  3QBP A;  1T6P A;  4FFX A;  1K7W A;  3CZO A;  4CQ5 A;  1DCN A;  1DOF A;  2O7D A;  3UNV A;  4APB A;  4C5U A;  3GTD A;  4C5R A;  3TV2 A;  1EB4 A;  2NYF A;  4C6G A;  3OCE A;  1FUQ A;  2HVG A;  2E9F A;  1C3C A;  1XWO A;  3C8T A;  4C5S A;  4NLE A;  1GK3 A;  1I0A A;  4MX2 A;  3GZH A;  1JSW A;  1TJV A;  1Y2M A;  4BAA A;  1AUW A;  2PTS A;  4V2Q A;  2YII A;  4HGV A;  4ADM A;  2O7B A;  3KDY A;  1T6J A;  1GK2 A;  1U16 A;  1HY0 A;  2QGA B;  1C3U A;  2J91 A;  3OCF A;  4EEI A;  3KDZ A;  5HW2 A;  1TJU A;  3NZ4 A;  4BAB A;  2FUS A;  1YFM A;  2VD6 A;  2PTQ A;  1FUO A;  5EYV A;  1GKM A;  2O7F A;  2O7E A;  3R6V A;  3RD8 A;  3RRP A;  2NYN A;  2RJR A;  2X75 A;  2QVE A;  4FLC A;  1VDK A;  1U15 A;  2O6Y A;  2PFM A;  2OHY A;  1Q5N A;  4ADL A;  3NO9 A;  1J3U A;  4APA A;  5D6B A;  2PTR A;  3R6Y A;  3E04 A;  4NSL A;  3R6Q A;  2RJS A;  4V2R A;  1FUP A;  3BHG A;  1TJW A;  5F91 A;  1B8F A;  2O78 A;  5EYT A;  1GKJ A;  4EFC A;  1KQ7 A;  1FUR A;  1W27 A;  1K62 A;  1RE5 A;  1TJ7 A;  1YIS A;  5F92 A;  1HY1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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