4MX2A

Crystal structure of adenylosuccinate lyase from leishmania donovani
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
453
structure length
424
Chain Sequence
EISQDSPLYSLSPLDGRYKRDTTPLRAYFSEYALFKYRVQVEVLYFEALCKEVPAITQLRGVTDAQLGELRATTFENFAVDDAKIIKGIEAVTNHDIKAVEYYLKDKMSACGLEAEKEFIHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEWDVPMLARTHGQPASPTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFLSKYLGLRRQRYTTQIEHYDNLAAICDACARLHTILMDLAKDVWQYISLGYFDQKVREVGVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGVPLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGVTEETVHRFVQQITEEVRQELLAITPFTYVGYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Adenylosuccinate lyase
publication title Crystal Structure of adenylosuccinate lyase from Leishmania donovani
rcsb
source organism Leishmania donovani
total genus 170
structure length 424
sequence length 453
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2013-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF08328 ASL_C Adenylosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4mx2A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4mx2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4mx2A02
2J91A 2PFMA 3OCFA 1YFEA 2HVGA 1J3UA 4APAA 4MX2A 4V2QA 3QBPA 3E04A 2NYNA 1DOFA 1EB4A 1C3CA 3R6QA 1YISA 1W27A 4EEIA 2QGAB 3GTDA 4ADMA 1B8FA 3KDZA 2E9FA 2QVEA 1GK3A 2X75A 4EFCA 1HY1A 1FUPA 1XWOA 4BAAA 5F91A 4HGVA 1YFMA 1VDKA 1T6JA 1K62A 2FUSA 1T6PA 4CQ5A 2O7BA 3R6VA 5HW2A 4FLCA 1FUQA 4C5UA 3NZ4A 1I0AA 4ADLA 1FURA 1TJWA 3CZOA 2VD6A 2O78A 2O6YA 2OHYA 4FFXA 4NSLA 2PTQA 4APBA 3NO9A 3BHGA 3UNVA 1DCNA 5EYVA 3GZHA 3C8TA 3RRPA 1FUOA 1TJ7A 5EYTA 4C6GA 2O7DA 2NYFA 1KQ7A 1TJUA 2RJRA 4C5SA 1K7WA 1GKMA 2YIIA 5F92A 1U15A 1AUWA 4C5RA 4NLEA 4V2RA 2PTRA 4BABA 2RJSA 1GKJA 1Y2MA 1TJVA 1GK2A 3TV2A 1JSWA 3OCEA 3R6YA 1C3UA 5D6BA 2O7EA 3RD8A 1HY0A 1Q5NA 2PTSA 1RE5A 3KDYA 2O7FA 1U16A
chains in the Genus database with same CATH superfamily
2J91A 2PFMA 3OCFA 5H8WA 1YFEA 2HVGA 1J3UA 1U0LA 3U13A 4MX2A 4APAA 4WNLA 4L57A 4V2QA 3QBPA 3E04A 2NYNA 1DOFA 3U19A 1EB4A 1C3CA 3R6QA 1YISA 4L6AA 1W27A 3BWVA 5M0IA 4EEIA 2QGAB 3GTDA 4ADMA 1B8FA 3KDZA 2E9FA 2QVEA 1GK3A 2X75A 4EFCA 1HY1A 1FUPA 1XWOA 4A15A 4BAAA 1Z4KA 5F91A 4E88A 4HGVA 1T9HA 1YFMA 1VDKA 1T6JA 1K62A 2FUSA 1T6PA 2VSFA 4CQ5A 2O7BA 3R6VA 5HW2A 4FLCA 1FUQA 1Z4IA 4MUMA 4C5UA 3NZ4A 1I0AA 4ADLA 1FURA 1TJWA 1Z4MA 3CZOA 3F4RA 2JAUA 1Z4JA 1XMDA 2VD6A 2O78A 2O6YA 2OHYA 2I7DA 4FFXA 1XL8A 1Z4LA 4NSLA 4YIKA 5M0JA 2PTQA 4APBA 3NO9A 1XMCA 1XLYA 3BHGA 3UNVA 2FENA 2JAOA 1DCNA 5EYVA 3GZHA 3C8TA 3RRPA 1FUOA 1TJ7A 5EYTA 4C6GA 2O7DA 1Z4PX 2NYFA 1KQ7A 1TJUA 2JAWA 2RJRA 4C5SA 2JARA 1K7WA 1MH9A 1GKMA 2YIIA 5F92A 1U15A 1Q91A 4YIHA 1AUWA 1Z4QA 4MWOA 4C5RA 4NFLA 4NLEA 4V2RA 2PTRA 2VL7A 3F4TA 4BABA 2RJSA 1IW7D 2YV5A 2D27A 1GKJA 1Y2MA 1TJVA 2D28C 1XL7A 4L6CA 1GK2A 3TV2A 4IQJM 1JSWA 3OCEA 2RCNA 3CI0K 3R6YA 1C3UA 5D6BA 2O7EA 3RD8A 3CRW1 1HY0A 1Q5NA 2PTSA 1RE5A 2FELA 3KDYA 3F4SA 1Q92A 2O7FA 1U16A 3CRVA
chains in the Genus database with same CATH topology
2J91A 2PFMA 3OCFA 1YFEA 2HVGA 1J3UA 4APAA 4MX2A 4V2QA 3QBPA 3E04A 2NYNA 1DOFA 1EB4A 1C3CA 3R6QA 1YISA 1W27A 4EEIA 2QGAB 3GTDA 4ADMA 1B8FA 3KDZA 2E9FA 2QVEA 1GK3A 2X75A 4EFCA 1HY1A 1FUPA 1XWOA 4BAAA 5F91A 4HGVA 1YFMA 1VDKA 1T6JA 1K62A 2FUSA 1T6PA 4CQ5A 2O7BA 3R6VA 5HW2A 4FLCA 1FUQA 4C5UA 3NZ4A 1I0AA 4ADLA 1FURA 1TJWA 3CZOA 2VD6A 2O78A 2O6YA 2OHYA 4FFXA 4NSLA 2PTQA 4APBA 3NO9A 3BHGA 3UNVA 1DCNA 5EYVA 3GZHA 3C8TA 3RRPA 1FUOA 1TJ7A 5EYTA 4C6GA 2O7DA 2NYFA 1KQ7A 1TJUA 2RJRA 4C5SA 1K7WA 1GKMA 2YIIA 5F92A 1U15A 1AUWA 4C5RA 4NLEA 4V2RA 2PTRA 4BABA 2RJSA 1GKJA 1Y2MA 1TJVA 1GK2A 3TV2A 1JSWA 3OCEA 3R6YA 1C3UA 5D6BA 2O7EA 3RD8A 1HY0A 1Q5NA 2PTSA 1RE5A 3KDYA 2O7FA 1U16A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J91 A;  2PFM A;  3OCF A;  1YFE A;  2HVG A;  1J3U A;  4APA A;  4MX2 A;  4V2Q A;  3QBP A;  3E04 A;  2NYN A;  1DOF A;  1EB4 A;  1C3C A;  3R6Q A;  1YIS A;  1W27 A;  4EEI A;  2QGA B;  3GTD A;  4ADM A;  1B8F A;  3KDZ A;  2E9F A;  2QVE A;  1GK3 A;  2X75 A;  4EFC A;  1HY1 A;  1FUP A;  1XWO A;  4BAA A;  5F91 A;  4HGV A;  1YFM A;  1VDK A;  1T6J A;  1K62 A;  2FUS A;  1T6P A;  4CQ5 A;  2O7B A;  3R6V A;  5HW2 A;  4FLC A;  1FUQ A;  4C5U A;  3NZ4 A;  1I0A A;  4ADL A;  1FUR A;  1TJW A;  3CZO A;  2VD6 A;  2O78 A;  2O6Y A;  2OHY A;  4FFX A;  4NSL A;  2PTQ A;  4APB A;  3NO9 A;  3BHG A;  3UNV A;  1DCN A;  5EYV A;  3GZH A;  3C8T A;  3RRP A;  1FUO A;  1TJ7 A;  5EYT A;  4C6G A;  2O7D A;  2NYF A;  1KQ7 A;  1TJU A;  2RJR A;  4C5S A;  1K7W A;  1GKM A;  2YII A;  5F92 A;  1U15 A;  1AUW A;  4C5R A;  4NLE A;  4V2R A;  2PTR A;  4BAB A;  2RJS A;  1GKJ A;  1Y2M A;  1TJV A;  1GK2 A;  3TV2 A;  1JSW A;  3OCE A;  3R6Y A;  1C3U A;  5D6B A;  2O7E A;  3RD8 A;  1HY0 A;  1Q5N A;  2PTS A;  1RE5 A;  3KDY A;  2O7F A;  1U16 A; 
#chains in the Genus database with same CATH topology
 2J91 A;  2PFM A;  3OCF A;  5H8W A;  1YFE A;  2HVG A;  1J3U A;  1U0L A;  3U13 A;  4MX2 A;  4APA A;  4WNL A;  4L57 A;  4V2Q A;  3QBP A;  3E04 A;  2NYN A;  1DOF A;  3U19 A;  1EB4 A;  1C3C A;  3R6Q A;  1YIS A;  4L6A A;  1W27 A;  3BWV A;  5M0I A;  4EEI A;  2QGA B;  3GTD A;  4ADM A;  1B8F A;  3KDZ A;  2E9F A;  2QVE A;  1GK3 A;  2X75 A;  4EFC A;  1HY1 A;  1FUP A;  1XWO A;  4A15 A;  4BAA A;  1Z4K A;  5F91 A;  4E88 A;  4HGV A;  1T9H A;  1YFM A;  1VDK A;  1T6J A;  1K62 A;  2FUS A;  1T6P A;  2VSF A;  4CQ5 A;  2O7B A;  3R6V A;  5HW2 A;  4FLC A;  1FUQ A;  1Z4I A;  4MUM A;  4C5U A;  3NZ4 A;  1I0A A;  4ADL A;  1FUR A;  1TJW A;  1Z4M A;  3CZO A;  3F4R A;  2JAU A;  1Z4J A;  1XMD A;  2VD6 A;  2O78 A;  2O6Y A;  2OHY A;  2I7D A;  4FFX A;  1XL8 A;  1Z4L A;  4NSL A;  4YIK A;  5M0J A;  2PTQ A;  4APB A;  3NO9 A;  1XMC A;  1XLY A;  3BHG A;  3UNV A;  2FEN A;  2JAO A;  1DCN A;  5EYV A;  3GZH A;  3C8T A;  3RRP A;  1FUO A;  1TJ7 A;  5EYT A;  4C6G A;  2O7D A;  1Z4P X;  2NYF A;  1KQ7 A;  1TJU A;  2JAW A;  2RJR A;  4C5S A;  2JAR A;  1K7W A;  1MH9 A;  1GKM A;  2YII A;  5F92 A;  1U15 A;  1Q91 A;  4YIH A;  1AUW A;  1Z4Q A;  4MWO A;  4C5R A;  4NFL A;  4NLE A;  4V2R A;  2PTR A;  2VL7 A;  3F4T A;  4BAB A;  2RJS A;  1IW7 D;  2YV5 A;  2D27 A;  1GKJ A;  1Y2M A;  1TJV A;  2D28 C;  1XL7 A;  4L6C A;  1GK2 A;  3TV2 A;  4IQJ M;  1JSW A;  3OCE A;  2RCN A;  3CI0 K;  3R6Y A;  1C3U A;  5D6B A;  2O7E A;  3RD8 A;  3CRW 1;  1HY0 A;  1Q5N A;  2PTS A;  1RE5 A;  2FEL A;  3KDY A;  3F4S A;  1Q92 A;  2O7F A;  1U16 A;  3CRV A; 
#chains in the Genus database with same CATH homology
 2J91 A;  2PFM A;  3OCF A;  1YFE A;  2HVG A;  1J3U A;  4APA A;  4MX2 A;  4V2Q A;  3QBP A;  3E04 A;  2NYN A;  1DOF A;  1EB4 A;  1C3C A;  3R6Q A;  1YIS A;  1W27 A;  4EEI A;  2QGA B;  3GTD A;  4ADM A;  1B8F A;  3KDZ A;  2E9F A;  2QVE A;  1GK3 A;  2X75 A;  4EFC A;  1HY1 A;  1FUP A;  1XWO A;  4BAA A;  5F91 A;  4HGV A;  1YFM A;  1VDK A;  1T6J A;  1K62 A;  2FUS A;  1T6P A;  4CQ5 A;  2O7B A;  3R6V A;  5HW2 A;  4FLC A;  1FUQ A;  4C5U A;  3NZ4 A;  1I0A A;  4ADL A;  1FUR A;  1TJW A;  3CZO A;  2VD6 A;  2O78 A;  2O6Y A;  2OHY A;  4FFX A;  4NSL A;  2PTQ A;  4APB A;  3NO9 A;  3BHG A;  3UNV A;  1DCN A;  5EYV A;  3GZH A;  3C8T A;  3RRP A;  1FUO A;  1TJ7 A;  5EYT A;  4C6G A;  2O7D A;  2NYF A;  1KQ7 A;  1TJU A;  2RJR A;  4C5S A;  1K7W A;  1GKM A;  2YII A;  5F92 A;  1U15 A;  1AUW A;  4C5R A;  4NLE A;  4V2R A;  2PTR A;  4BAB A;  2RJS A;  1GKJ A;  1Y2M A;  1TJV A;  1GK2 A;  3TV2 A;  1JSW A;  3OCE A;  3R6Y A;  1C3U A;  5D6B A;  2O7E A;  3RD8 A;  1HY0 A;  1Q5N A;  2PTS A;  1RE5 A;  3KDY A;  2O7F A;  1U16 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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