2OHYA

X-ray crystal structure of tyrosine aminomutase from streptomyces globisporus
Total Genus 191
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
191
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Tyrosine aminomutase
publication title The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Lyase, transferase
total genus 191
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2ohyA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2ohyA02
3C8TA 1KQ7A 2QVEA 3R6VA 3NO9A 3R6QA 2O78A 3UNVA 1YISA 5D6BA 3CZOA 1DCNA 1I0AA 1RE5A 2O6YA 1YFMA 3GTDA 1J3UA 1TJUA 1AUWA 1T6JA 4BABA 4BAAA 1B8FA 2X75A 2VD6A 1U15A 5EYVA 2QGAB 2OHYA 1C3CA 1TJVA 4V2RA 4APAA 1K7WA 3OCFA 1C3UA 1VDKA 3R6YA 4APBA 2O7BA 1YFEA 2PTQA 4MX2A 4C5RA 4V2QA 3RRPA 3QBPA 4EFCA 1FUOA 4C6GA 2E9FA 1U16A 2PTRA 1GK2A 3TV2A 2YIIA 4ADLA 2HVGA 5F92A 3NZ4A 1T6PA 1FUPA 5F91A 3BHGA 1FUQA 4HGVA 4C5SA 2J91A 1HY1A 3GZHA 4C5UA 1GKJA 2O7FA 1EB4A 4NLEA 1Y2MA 2RJSA 3E04A 3KDYA 5EYTA 1DOFA 1Q5NA 2NYFA 2O7DA 1TJ7A 1K62A 4CQ5A 2O7EA 1GKMA 2RJRA 4ADMA 2NYNA 4EEIA 3KDZA 1XWOA 2PTSA 1FURA 4FFXA 2FUSA 1GK3A 4FLCA 1W27A 5HW2A 1JSWA 4NSLA 3RD8A 2PFMA 1HY0A 3OCEA 1TJWA
chains in the Genus database with same CATH superfamily
5M0JA 3C8TA 1KQ7A 2QVEA 3CRW1 3R6VA 3NO9A 3R6QA 2O78A 3UNVA 1YISA 5D6BA 3CZOA 1DCNA 1I0AA 1RE5A 4WNLA 1XL7A 2O6YA 1YFMA 3GTDA 1J3UA 1TJUA 1AUWA 1T6JA 4BABA 1XL8A 4BAAA 1B8FA 2X75A 2VD6A 1U15A 5EYVA 2QGAB 2OHYA 1C3CA 3CRVA 1TJVA 4V2RA 4APAA 1K7WA 3OCFA 1C3UA 1VDKA 3R6YA 4APBA 2O7BA 1YFEA 2PTQA 4MX2A 1TJWA 4C5RA 2FENA 4V2QA 3RRPA 3QBPA 4EFCA 1FUOA 4C6GA 1U16A 2PTRA 1GK2A 3TV2A 2YIIA 4ADLA 2HVGA 1XMDA 5F92A 3NZ4A 5H8WA 1T6PA 1FUPA 5F91A 2VSFA 3BHGA 4A15A 1FUQA 4HGVA 4C5SA 2J91A 1HY1A 3GZHA 4C5UA 1GKJA 2O7FA 1EB4A 4NLEA 1Y2MA 2RJSA 5M0IA 3E04A 1XLYA 3KDYA 5EYTA 1DOFA 1Q5NA 2NYFA 2O7DA 1TJ7A 1K62A 4CQ5A 2O7EA 1GKMA 2RJRA 2FELA 4ADMA 2NYNA 2VL7A 4EEIA 3KDZA 1XWOA 1XMCA 2PTSA 1FURA 4FFXA 2FUSA 1GK3A 4FLCA 1W27A 5HW2A 1JSWA 4NSLA 3RD8A 2PFMA 1HY0A 3OCEA 2E9FA
chains in the Genus database with same CATH topology
3C8TA 1KQ7A 2QVEA 3R6VA 3NO9A 3R6QA 2O78A 3UNVA 1YISA 5D6BA 3CZOA 1DCNA 1I0AA 1RE5A 2O6YA 1YFMA 3GTDA 1J3UA 1TJUA 1AUWA 1T6JA 4BABA 4BAAA 1B8FA 2X75A 2VD6A 1U15A 5EYVA 2QGAB 2OHYA 1C3CA 1TJVA 4V2RA 4APAA 1K7WA 3OCFA 1C3UA 1VDKA 3R6YA 4APBA 2O7BA 1YFEA 2PTQA 4MX2A 4C5RA 4V2QA 3RRPA 3QBPA 4EFCA 1FUOA 4C6GA 2E9FA 1U16A 2PTRA 1GK2A 3TV2A 2YIIA 4ADLA 2HVGA 5F92A 3NZ4A 1T6PA 1FUPA 5F91A 3BHGA 1FUQA 4HGVA 4C5SA 2J91A 1HY1A 3GZHA 4C5UA 1GKJA 2O7FA 1EB4A 4NLEA 1Y2MA 2RJSA 3E04A 3KDYA 5EYTA 1DOFA 1Q5NA 2NYFA 2O7DA 1TJ7A 1K62A 4CQ5A 2O7EA 1GKMA 2RJRA 4ADMA 2NYNA 4EEIA 3KDZA 1XWOA 2PTSA 1FURA 4FFXA 2FUSA 1GK3A 4FLCA 1W27A 5HW2A 1JSWA 4NSLA 3RD8A 2PFMA 1HY0A 3OCEA 1TJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C8T A;  1KQ7 A;  2QVE A;  3R6V A;  3NO9 A;  3R6Q A;  2O78 A;  3UNV A;  1YIS A;  5D6B A;  3CZO A;  1DCN A;  1I0A A;  1RE5 A;  2O6Y A;  1YFM A;  3GTD A;  1J3U A;  1TJU A;  1AUW A;  1T6J A;  4BAB A;  4BAA A;  1B8F A;  2X75 A;  2VD6 A;  1U15 A;  5EYV A;  2QGA B;  2OHY A;  1C3C A;  1TJV A;  4V2R A;  4APA A;  1K7W A;  3OCF A;  1C3U A;  1VDK A;  3R6Y A;  4APB A;  2O7B A;  1YFE A;  2PTQ A;  4MX2 A;  4C5R A;  4V2Q A;  3RRP A;  3QBP A;  4EFC A;  1FUO A;  4C6G A;  2E9F A;  1U16 A;  2PTR A;  1GK2 A;  3TV2 A;  2YII A;  4ADL A;  2HVG A;  5F92 A;  3NZ4 A;  1T6P A;  1FUP A;  5F91 A;  3BHG A;  1FUQ A;  4HGV A;  4C5S A;  2J91 A;  1HY1 A;  3GZH A;  4C5U A;  1GKJ A;  2O7F A;  1EB4 A;  4NLE A;  1Y2M A;  2RJS A;  3E04 A;  3KDY A;  5EYT A;  1DOF A;  1Q5N A;  2NYF A;  2O7D A;  1TJ7 A;  1K62 A;  4CQ5 A;  2O7E A;  1GKM A;  2RJR A;  4ADM A;  2NYN A;  4EEI A;  3KDZ A;  1XWO A;  2PTS A;  1FUR A;  4FFX A;  2FUS A;  1GK3 A;  4FLC A;  1W27 A;  5HW2 A;  1JSW A;  4NSL A;  3RD8 A;  2PFM A;  1HY0 A;  3OCE A;  1TJW A; 
#chains in the Genus database with same CATH topology
 5M0J A;  3C8T A;  1KQ7 A;  2QVE A;  3CRW 1;  3R6V A;  3NO9 A;  3R6Q A;  2O78 A;  3UNV A;  1YIS A;  5D6B A;  3CZO A;  1DCN A;  1I0A A;  1RE5 A;  4WNL A;  1XL7 A;  2O6Y A;  1YFM A;  3GTD A;  1J3U A;  1TJU A;  1AUW A;  1T6J A;  4BAB A;  1XL8 A;  4BAA A;  1B8F A;  2X75 A;  2VD6 A;  1U15 A;  5EYV A;  2QGA B;  2OHY A;  1C3C A;  3CRV A;  1TJV A;  4V2R A;  4APA A;  1K7W A;  3OCF A;  1C3U A;  1VDK A;  3R6Y A;  4APB A;  2O7B A;  1YFE A;  2PTQ A;  4MX2 A;  1TJW A;  4C5R A;  2FEN A;  4V2Q A;  3RRP A;  3QBP A;  4EFC A;  1FUO A;  4C6G A;  1U16 A;  2PTR A;  1GK2 A;  3TV2 A;  2YII A;  4ADL A;  2HVG A;  1XMD A;  5F92 A;  3NZ4 A;  5H8W A;  1T6P A;  1FUP A;  5F91 A;  2VSF A;  3BHG A;  4A15 A;  1FUQ A;  4HGV A;  4C5S A;  2J91 A;  1HY1 A;  3GZH A;  4C5U A;  1GKJ A;  2O7F A;  1EB4 A;  4NLE A;  1Y2M A;  2RJS A;  5M0I A;  3E04 A;  1XLY A;  3KDY A;  5EYT A;  1DOF A;  1Q5N A;  2NYF A;  2O7D A;  1TJ7 A;  1K62 A;  4CQ5 A;  2O7E A;  1GKM A;  2RJR A;  2FEL A;  4ADM A;  2NYN A;  2VL7 A;  4EEI A;  3KDZ A;  1XWO A;  1XMC A;  2PTS A;  1FUR A;  4FFX A;  2FUS A;  1GK3 A;  4FLC A;  1W27 A;  5HW2 A;  1JSW A;  4NSL A;  3RD8 A;  2PFM A;  1HY0 A;  3OCE A;  2E9F A; 
#chains in the Genus database with same CATH homology
 3C8T A;  1KQ7 A;  2QVE A;  3R6V A;  3NO9 A;  3R6Q A;  2O78 A;  3UNV A;  1YIS A;  5D6B A;  3CZO A;  1DCN A;  1I0A A;  1RE5 A;  2O6Y A;  1YFM A;  3GTD A;  1J3U A;  1TJU A;  1AUW A;  1T6J A;  4BAB A;  4BAA A;  1B8F A;  2X75 A;  2VD6 A;  1U15 A;  5EYV A;  2QGA B;  2OHY A;  1C3C A;  1TJV A;  4V2R A;  4APA A;  1K7W A;  3OCF A;  1C3U A;  1VDK A;  3R6Y A;  4APB A;  2O7B A;  1YFE A;  2PTQ A;  4MX2 A;  4C5R A;  4V2Q A;  3RRP A;  3QBP A;  4EFC A;  1FUO A;  4C6G A;  2E9F A;  1U16 A;  2PTR A;  1GK2 A;  3TV2 A;  2YII A;  4ADL A;  2HVG A;  5F92 A;  3NZ4 A;  1T6P A;  1FUP A;  5F91 A;  3BHG A;  1FUQ A;  4HGV A;  4C5S A;  2J91 A;  1HY1 A;  3GZH A;  4C5U A;  1GKJ A;  2O7F A;  1EB4 A;  4NLE A;  1Y2M A;  2RJS A;  3E04 A;  3KDY A;  5EYT A;  1DOF A;  1Q5N A;  2NYF A;  2O7D A;  1TJ7 A;  1K62 A;  4CQ5 A;  2O7E A;  1GKM A;  2RJR A;  4ADM A;  2NYN A;  4EEI A;  3KDZ A;  1XWO A;  2PTS A;  1FUR A;  4FFX A;  2FUS A;  1GK3 A;  4FLC A;  1W27 A;  5HW2 A;  1JSW A;  4NSL A;  3RD8 A;  2PFM A;  1HY0 A;  3OCE A;  1TJW A; 
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