2OHYA

X-ray crystal structure of tyrosine aminomutase from streptomyces globisporus
Total Genus 191
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
191
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway
pubmed doi rcsb
source organism Streptomyces globisporus
molecule tags Lyase, transferase
molecule keywords Tyrosine aminomutase
total genus 191
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2ohyA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2ohyA02
1GK3A 3R6VA 4V2QA 3R6QA 1JSWA 3BHGA 1FUPA 1FUOA 1C3UA 1YFMA 2NYFA 1GKMA 2O7DA 4ADMA 1GKJA 2PTSA 1XWOA 1AUWA 2OHYA 2VD6A 3E04A 2NYNA 4APAA 1T6JA 3OCFA 4BABA 2RJSA 3OCEA 1W27A 4EEIA 1TJ7A 2J91A 1EB4A 1YISA 2PFMA 1U15A 4C5SA 1DOFA 1GK2A 2FUSA 3CZOA 1K7WA 1Q5NA 2PTQA 3UNVA 4APBA 3RD8A 3TV2A 4CQ5A 2O7FA 2PTRA 1I0AA 3RRPA 4V2RA 1C3CA 1K62A 3NZ4A 4HGVA 1U16A 4C5UA 1B8FA 4NLEA 1Y2MA 5EYVA 2YIIA 1VDKA 4MX2A 4BAAA 1YFEA 3GTDA 2O7BA 4NSLA 5F92A 5EYTA 1TJUA 5D6BA 2QVEA 1RE5A 1J3UA 2O78A 4EFCA 1FURA 3QBPA 4ADLA 1FUQA 1KQ7A 1TJWA 3NO9A 2RJRA 5F91A 4C5RA 1HY1A 2HVGA 2E9FA 3KDYA 1HY0A 3C8TA 1T6PA 5HW2A 1TJVA 1DCNA 4FLCA 2O7EA 3GZHA 4C6GA 2QGAB 2X75A 3R6YA 3KDZA 4FFXA 2O6YA
chains in the Genus database with same CATH superfamily
1GK3A 3R6VA 4V2QA 3R6QA 2VL7A 1JSWA 3BHGA 1FUPA 1FUOA 1C3UA 1YFMA 2NYFA 1GKMA 2O7DA 4ADMA 1GKJA 2PTSA 1XWOA 3CRW1 1AUWA 3CRVA 2OHYA 2VD6A 3E04A 2NYNA 4APAA 1T6JA 3OCFA 4BABA 2RJSA 3OCEA 1W27A 4EEIA 1TJ7A 2J91A 1EB4A 1YISA 2FENA 2PFMA 1U15A 4C5SA 1DOFA 1GK2A 2FUSA 3CZOA 1K7WA 1Q5NA 1XL7A 2PTQA 2FELA 3UNVA 4APBA 3RD8A 3TV2A 4CQ5A 2O7FA 2PTRA 1I0AA 3RRPA 4V2RA 1C3CA 1K62A 3NZ4A 4HGVA 1U16A 4C5UA 1B8FA 4NLEA 1Y2MA 5EYVA 2YIIA 1VDKA 4MX2A 4BAAA 1YFEA 3GTDA 2O7BA 4NSLA 5F92A 5EYTA 1TJUA 5D6BA 2QVEA 1RE5A 1XMDA 1XLYA 1J3UA 2O78A 5M0JA 4EFCA 1FURA 3QBPA 4ADLA 4A15A 1FUQA 1KQ7A 1TJWA 3NO9A 2RJRA 5F91A 4C5RA 1HY1A 2HVGA 2E9FA 3KDYA 1HY0A 3C8TA 1T6PA 5M0IA 5HW2A 1TJVA 1XMCA 2VSFA 1DCNA 4FLCA 2O7EA 3GZHA 4C6GA 2QGAB 2X75A 4WNLA 3R6YA 3KDZA 1XL8A 4FFXA 2O6YA 5H8WA
chains in the Genus database with same CATH topology
1GK3A 3R6VA 4V2QA 3R6QA 1JSWA 3BHGA 1FUPA 1FUOA 1C3UA 1YFMA 2NYFA 1GKMA 2O7DA 4ADMA 1GKJA 2PTSA 1XWOA 1AUWA 2OHYA 2VD6A 3E04A 2NYNA 4APAA 1T6JA 3OCFA 4BABA 2RJSA 3OCEA 1W27A 4EEIA 1TJ7A 2J91A 1EB4A 1YISA 2PFMA 1U15A 4C5SA 1DOFA 1GK2A 2FUSA 3CZOA 1K7WA 1Q5NA 2PTQA 3UNVA 4APBA 3RD8A 3TV2A 4CQ5A 2O7FA 2PTRA 1I0AA 3RRPA 4V2RA 1C3CA 1K62A 3NZ4A 4HGVA 1U16A 4C5UA 1B8FA 4NLEA 1Y2MA 5EYVA 2YIIA 1VDKA 4MX2A 4BAAA 1YFEA 3GTDA 2O7BA 4NSLA 5F92A 5EYTA 1TJUA 5D6BA 2QVEA 1RE5A 1J3UA 2O78A 4EFCA 1FURA 3QBPA 4ADLA 1FUQA 1KQ7A 1TJWA 3NO9A 2RJRA 5F91A 4C5RA 1HY1A 2HVGA 2E9FA 3KDYA 1HY0A 3C8TA 1T6PA 5HW2A 1TJVA 1DCNA 4FLCA 2O7EA 3GZHA 4C6GA 2QGAB 2X75A 3R6YA 3KDZA 4FFXA 2O6YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GK3 A;  3R6V A;  4V2Q A;  3R6Q A;  1JSW A;  3BHG A;  1FUP A;  1FUO A;  1C3U A;  1YFM A;  2NYF A;  1GKM A;  2O7D A;  4ADM A;  1GKJ A;  2PTS A;  1XWO A;  1AUW A;  2OHY A;  2VD6 A;  3E04 A;  2NYN A;  4APA A;  1T6J A;  3OCF A;  4BAB A;  2RJS A;  3OCE A;  1W27 A;  4EEI A;  1TJ7 A;  2J91 A;  1EB4 A;  1YIS A;  2PFM A;  1U15 A;  4C5S A;  1DOF A;  1GK2 A;  2FUS A;  3CZO A;  1K7W A;  1Q5N A;  2PTQ A;  3UNV A;  4APB A;  3RD8 A;  3TV2 A;  4CQ5 A;  2O7F A;  2PTR A;  1I0A A;  3RRP A;  4V2R A;  1C3C A;  1K62 A;  3NZ4 A;  4HGV A;  1U16 A;  4C5U A;  1B8F A;  4NLE A;  1Y2M A;  5EYV A;  2YII A;  1VDK A;  4MX2 A;  4BAA A;  1YFE A;  3GTD A;  2O7B A;  4NSL A;  5F92 A;  5EYT A;  1TJU A;  5D6B A;  2QVE A;  1RE5 A;  1J3U A;  2O78 A;  4EFC A;  1FUR A;  3QBP A;  4ADL A;  1FUQ A;  1KQ7 A;  1TJW A;  3NO9 A;  2RJR A;  5F91 A;  4C5R A;  1HY1 A;  2HVG A;  2E9F A;  3KDY A;  1HY0 A;  3C8T A;  1T6P A;  5HW2 A;  1TJV A;  1DCN A;  4FLC A;  2O7E A;  3GZH A;  4C6G A;  2QGA B;  2X75 A;  3R6Y A;  3KDZ A;  4FFX A;  2O6Y A; 
#chains in the Genus database with same CATH topology
 1GK3 A;  3R6V A;  4V2Q A;  3R6Q A;  2VL7 A;  1JSW A;  3BHG A;  1FUP A;  1FUO A;  1C3U A;  1YFM A;  2NYF A;  1GKM A;  2O7D A;  4ADM A;  1GKJ A;  2PTS A;  1XWO A;  3CRW 1;  1AUW A;  3CRV A;  2OHY A;  2VD6 A;  3E04 A;  2NYN A;  4APA A;  1T6J A;  3OCF A;  4BAB A;  2RJS A;  3OCE A;  1W27 A;  4EEI A;  1TJ7 A;  2J91 A;  1EB4 A;  1YIS A;  2FEN A;  2PFM A;  1U15 A;  4C5S A;  1DOF A;  1GK2 A;  2FUS A;  3CZO A;  1K7W A;  1Q5N A;  1XL7 A;  2PTQ A;  2FEL A;  3UNV A;  4APB A;  3RD8 A;  3TV2 A;  4CQ5 A;  2O7F A;  2PTR A;  1I0A A;  3RRP A;  4V2R A;  1C3C A;  1K62 A;  3NZ4 A;  4HGV A;  1U16 A;  4C5U A;  1B8F A;  4NLE A;  1Y2M A;  5EYV A;  2YII A;  1VDK A;  4MX2 A;  4BAA A;  1YFE A;  3GTD A;  2O7B A;  4NSL A;  5F92 A;  5EYT A;  1TJU A;  5D6B A;  2QVE A;  1RE5 A;  1XMD A;  1XLY A;  1J3U A;  2O78 A;  5M0J A;  4EFC A;  1FUR A;  3QBP A;  4ADL A;  4A15 A;  1FUQ A;  1KQ7 A;  1TJW A;  3NO9 A;  2RJR A;  5F91 A;  4C5R A;  1HY1 A;  2HVG A;  2E9F A;  3KDY A;  1HY0 A;  3C8T A;  1T6P A;  5M0I A;  5HW2 A;  1TJV A;  1XMC A;  2VSF A;  1DCN A;  4FLC A;  2O7E A;  3GZH A;  4C6G A;  2QGA B;  2X75 A;  4WNL A;  3R6Y A;  3KDZ A;  1XL8 A;  4FFX A;  2O6Y A;  5H8W A; 
#chains in the Genus database with same CATH homology
 1GK3 A;  3R6V A;  4V2Q A;  3R6Q A;  1JSW A;  3BHG A;  1FUP A;  1FUO A;  1C3U A;  1YFM A;  2NYF A;  1GKM A;  2O7D A;  4ADM A;  1GKJ A;  2PTS A;  1XWO A;  1AUW A;  2OHY A;  2VD6 A;  3E04 A;  2NYN A;  4APA A;  1T6J A;  3OCF A;  4BAB A;  2RJS A;  3OCE A;  1W27 A;  4EEI A;  1TJ7 A;  2J91 A;  1EB4 A;  1YIS A;  2PFM A;  1U15 A;  4C5S A;  1DOF A;  1GK2 A;  2FUS A;  3CZO A;  1K7W A;  1Q5N A;  2PTQ A;  3UNV A;  4APB A;  3RD8 A;  3TV2 A;  4CQ5 A;  2O7F A;  2PTR A;  1I0A A;  3RRP A;  4V2R A;  1C3C A;  1K62 A;  3NZ4 A;  4HGV A;  1U16 A;  4C5U A;  1B8F A;  4NLE A;  1Y2M A;  5EYV A;  2YII A;  1VDK A;  4MX2 A;  4BAA A;  1YFE A;  3GTD A;  2O7B A;  4NSL A;  5F92 A;  5EYT A;  1TJU A;  5D6B A;  2QVE A;  1RE5 A;  1J3U A;  2O78 A;  4EFC A;  1FUR A;  3QBP A;  4ADL A;  1FUQ A;  1KQ7 A;  1TJW A;  3NO9 A;  2RJR A;  5F91 A;  4C5R A;  1HY1 A;  2HVG A;  2E9F A;  3KDY A;  1HY0 A;  3C8T A;  1T6P A;  5HW2 A;  1TJV A;  1DCN A;  4FLC A;  2O7E A;  3GZH A;  4C6G A;  2QGA B;  2X75 A;  3R6Y A;  3KDZ A;  4FFX A;  2O6Y A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...