2OHYA

X-ray crystal structure of tyrosine aminomutase from streptomyces globisporus
Total Genus 191
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
191
sequence length
526
structure length
525
Chain Sequence
PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase, transferase
molecule keywords Tyrosine aminomutase
publication title The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway
pubmed doi rcsb
source organism Streptomyces globisporus
total genus 191
structure length 525
sequence length 526
chains with identical sequence B
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2007-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2ohyA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2ohyA02
1YFMA 5F92A 2PFMA 1XWOA 1YISA 4BABA 1TJUA 1DOFA 1K62A 2O7DA 1TJVA 1GKJA 5F91A 2FUSA 1C3CA 4C5UA 5D6BA 2YIIA 2QGAB 1GK2A 4ADLA 4CQ5A 4EFCA 3GZHA 3E04A 1U15A 2VD6A 2PTSA 2O78A 1Q5NA 1TJWA 1I0AA 1FURA 1U16A 1B8FA 1KQ7A 3KDYA 2PTQA 4C5RA 1TJ7A 5HW2A 1W27A 2E9FA 4NLEA 1YFEA 5EYVA 2NYFA 1GKMA 3R6YA 1T6PA 3OCFA 3NO9A 1AUWA 2O7EA 3CZOA 1RE5A 3R6VA 2O7FA 3R6QA 2PTRA 1JSWA 2NYNA 4APBA 3OCEA 4ADMA 1HY0A 1GK3A 1FUOA 4MX2A 4V2QA 4APAA 1HY1A 2J91A 2QVEA 1FUQA 1EB4A 1T6JA 3RD8A 3BHGA 3TV2A 1K7WA 2O6YA 2HVGA 3KDZA 4C5SA 3GTDA 4C6GA 1J3UA 4BAAA 3QBPA 1DCNA 5EYTA 2RJSA 1C3UA 4EEIA 2OHYA 3RRPA 1VDKA 2O7BA 1Y2MA 3C8TA 3UNVA 4V2RA 1FUPA 4NSLA 3NZ4A 4FFXA 4HGVA 2X75A 4FLCA 2RJRA
chains in the Genus database with same CATH superfamily
1YFMA 4WNLA 5F92A 2PFMA 1XWOA 1YISA 4BABA 1TJUA 4A15A 1DOFA 1K62A 2O7DA 1TJVA 1GKJA 5F91A 5H8WA 2FUSA 1C3CA 4C5UA 5D6BA 2YIIA 2QGAB 1GK2A 4ADLA 4CQ5A 4EFCA 3GZHA 3E04A 1U15A 2VD6A 2PTSA 2O78A 1Q5NA 1TJWA 1I0AA 1FURA 1U16A 1B8FA 2FENA 1XLYA 1KQ7A 3KDYA 2FELA 2PTQA 4C5RA 1TJ7A 5HW2A 1W27A 1XMCA 2E9FA 4NLEA 1YFEA 5EYVA 5M0IA 2NYFA 1GKMA 3R6YA 1T6PA 3OCFA 3NO9A 1AUWA 2O7EA 3CZOA 1RE5A 3R6VA 2O7FA 3R6QA 2PTRA 1JSWA 2NYNA 4APBA 3OCEA 4ADMA 1HY0A 1GK3A 1FUOA 4MX2A 4V2QA 4APAA 1HY1A 2J91A 1XL8A 2QVEA 1FUQA 1EB4A 1T6JA 3CRVA 3RD8A 3BHGA 3TV2A 1K7WA 2O6YA 3CRW1 1XMDA 2HVGA 3KDZA 4C5SA 3GTDA 4C6GA 1J3UA 1XL7A 4BAAA 3QBPA 1DCNA 5EYTA 2RJSA 1C3UA 2VSFA 4EEIA 2OHYA 2VL7A 3RRPA 1VDKA 2O7BA 1Y2MA 3C8TA 3UNVA 4V2RA 1FUPA 5M0JA 4NSLA 3NZ4A 4FFXA 4HGVA 2X75A 4FLCA 2RJRA
chains in the Genus database with same CATH topology
1YFMA 5F92A 2PFMA 1XWOA 1YISA 4BABA 1TJUA 1DOFA 1K62A 2O7DA 1TJVA 1GKJA 5F91A 2FUSA 1C3CA 4C5UA 5D6BA 2YIIA 2QGAB 1GK2A 4ADLA 4CQ5A 4EFCA 3GZHA 3E04A 1U15A 2VD6A 2PTSA 2O78A 1Q5NA 1TJWA 1I0AA 1FURA 1U16A 1B8FA 1KQ7A 3KDYA 2PTQA 4C5RA 1TJ7A 5HW2A 1W27A 2E9FA 4NLEA 1YFEA 5EYVA 2NYFA 1GKMA 3R6YA 1T6PA 3OCFA 3NO9A 1AUWA 2O7EA 3CZOA 1RE5A 3R6VA 2O7FA 3R6QA 2PTRA 1JSWA 2NYNA 4APBA 3OCEA 4ADMA 1HY0A 1GK3A 1FUOA 4MX2A 4V2QA 4APAA 1HY1A 2J91A 2QVEA 1FUQA 1EB4A 1T6JA 3RD8A 3BHGA 3TV2A 1K7WA 2O6YA 2HVGA 3KDZA 4C5SA 3GTDA 4C6GA 1J3UA 4BAAA 3QBPA 1DCNA 5EYTA 2RJSA 1C3UA 4EEIA 2OHYA 3RRPA 1VDKA 2O7BA 1Y2MA 3C8TA 3UNVA 4V2RA 1FUPA 4NSLA 3NZ4A 4FFXA 4HGVA 2X75A 4FLCA 2RJRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YFM A;  5F92 A;  2PFM A;  1XWO A;  1YIS A;  4BAB A;  1TJU A;  1DOF A;  1K62 A;  2O7D A;  1TJV A;  1GKJ A;  5F91 A;  2FUS A;  1C3C A;  4C5U A;  5D6B A;  2YII A;  2QGA B;  1GK2 A;  4ADL A;  4CQ5 A;  4EFC A;  3GZH A;  3E04 A;  1U15 A;  2VD6 A;  2PTS A;  2O78 A;  1Q5N A;  1TJW A;  1I0A A;  1FUR A;  1U16 A;  1B8F A;  1KQ7 A;  3KDY A;  2PTQ A;  4C5R A;  1TJ7 A;  5HW2 A;  1W27 A;  2E9F A;  4NLE A;  1YFE A;  5EYV A;  2NYF A;  1GKM A;  3R6Y A;  1T6P A;  3OCF A;  3NO9 A;  1AUW A;  2O7E A;  3CZO A;  1RE5 A;  3R6V A;  2O7F A;  3R6Q A;  2PTR A;  1JSW A;  2NYN A;  4APB A;  3OCE A;  4ADM A;  1HY0 A;  1GK3 A;  1FUO A;  4MX2 A;  4V2Q A;  4APA A;  1HY1 A;  2J91 A;  2QVE A;  1FUQ A;  1EB4 A;  1T6J A;  3RD8 A;  3BHG A;  3TV2 A;  1K7W A;  2O6Y A;  2HVG A;  3KDZ A;  4C5S A;  3GTD A;  4C6G A;  1J3U A;  4BAA A;  3QBP A;  1DCN A;  5EYT A;  2RJS A;  1C3U A;  4EEI A;  2OHY A;  3RRP A;  1VDK A;  2O7B A;  1Y2M A;  3C8T A;  3UNV A;  4V2R A;  1FUP A;  4NSL A;  3NZ4 A;  4FFX A;  4HGV A;  2X75 A;  4FLC A;  2RJR A; 
#chains in the Genus database with same CATH topology
 1YFM A;  4WNL A;  5F92 A;  2PFM A;  1XWO A;  1YIS A;  4BAB A;  1TJU A;  4A15 A;  1DOF A;  1K62 A;  2O7D A;  1TJV A;  1GKJ A;  5F91 A;  5H8W A;  2FUS A;  1C3C A;  4C5U A;  5D6B A;  2YII A;  2QGA B;  1GK2 A;  4ADL A;  4CQ5 A;  4EFC A;  3GZH A;  3E04 A;  1U15 A;  2VD6 A;  2PTS A;  2O78 A;  1Q5N A;  1TJW A;  1I0A A;  1FUR A;  1U16 A;  1B8F A;  2FEN A;  1XLY A;  1KQ7 A;  3KDY A;  2FEL A;  2PTQ A;  4C5R A;  1TJ7 A;  5HW2 A;  1W27 A;  1XMC A;  2E9F A;  4NLE A;  1YFE A;  5EYV A;  5M0I A;  2NYF A;  1GKM A;  3R6Y A;  1T6P A;  3OCF A;  3NO9 A;  1AUW A;  2O7E A;  3CZO A;  1RE5 A;  3R6V A;  2O7F A;  3R6Q A;  2PTR A;  1JSW A;  2NYN A;  4APB A;  3OCE A;  4ADM A;  1HY0 A;  1GK3 A;  1FUO A;  4MX2 A;  4V2Q A;  4APA A;  1HY1 A;  2J91 A;  1XL8 A;  2QVE A;  1FUQ A;  1EB4 A;  1T6J A;  3CRV A;  3RD8 A;  3BHG A;  3TV2 A;  1K7W A;  2O6Y A;  3CRW 1;  1XMD A;  2HVG A;  3KDZ A;  4C5S A;  3GTD A;  4C6G A;  1J3U A;  1XL7 A;  4BAA A;  3QBP A;  1DCN A;  5EYT A;  2RJS A;  1C3U A;  2VSF A;  4EEI A;  2OHY A;  2VL7 A;  3RRP A;  1VDK A;  2O7B A;  1Y2M A;  3C8T A;  3UNV A;  4V2R A;  1FUP A;  5M0J A;  4NSL A;  3NZ4 A;  4FFX A;  4HGV A;  2X75 A;  4FLC A;  2RJR A; 
#chains in the Genus database with same CATH homology
 1YFM A;  5F92 A;  2PFM A;  1XWO A;  1YIS A;  4BAB A;  1TJU A;  1DOF A;  1K62 A;  2O7D A;  1TJV A;  1GKJ A;  5F91 A;  2FUS A;  1C3C A;  4C5U A;  5D6B A;  2YII A;  2QGA B;  1GK2 A;  4ADL A;  4CQ5 A;  4EFC A;  3GZH A;  3E04 A;  1U15 A;  2VD6 A;  2PTS A;  2O78 A;  1Q5N A;  1TJW A;  1I0A A;  1FUR A;  1U16 A;  1B8F A;  1KQ7 A;  3KDY A;  2PTQ A;  4C5R A;  1TJ7 A;  5HW2 A;  1W27 A;  2E9F A;  4NLE A;  1YFE A;  5EYV A;  2NYF A;  1GKM A;  3R6Y A;  1T6P A;  3OCF A;  3NO9 A;  1AUW A;  2O7E A;  3CZO A;  1RE5 A;  3R6V A;  2O7F A;  3R6Q A;  2PTR A;  1JSW A;  2NYN A;  4APB A;  3OCE A;  4ADM A;  1HY0 A;  1GK3 A;  1FUO A;  4MX2 A;  4V2Q A;  4APA A;  1HY1 A;  2J91 A;  2QVE A;  1FUQ A;  1EB4 A;  1T6J A;  3RD8 A;  3BHG A;  3TV2 A;  1K7W A;  2O6Y A;  2HVG A;  3KDZ A;  4C5S A;  3GTD A;  4C6G A;  1J3U A;  4BAA A;  3QBP A;  1DCN A;  5EYT A;  2RJS A;  1C3U A;  4EEI A;  2OHY A;  3RRP A;  1VDK A;  2O7B A;  1Y2M A;  3C8T A;  3UNV A;  4V2R A;  1FUP A;  4NSL A;  3NZ4 A;  4FFX A;  4HGV A;  2X75 A;  4FLC A;  2RJR A; 
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