1GK2A

Histidine ammonia-lyase (hal) mutant f329g from pseudomonas putida
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
509
structure length
509
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNGHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Autocatalytic Peptide Cyclization During Chain Folding of Histidine Ammonia-Lyase.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
molecule keywords HISTIDINE AMMONIA-LYASE
total genus 194
structure length 509
sequence length 509
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gk2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gk2A02
2O7EA 3R6VA 2PTRA 4FFXA 4MX2A 2O78A 1Q5NA 3OCFA 1RE5A 1GKMA 3KDYA 5D6BA 1Y2MA 4ADMA 3BHGA 1W27A 3CZOA 1K62A 3C8TA 1KQ7A 1EB4A 2FUSA 4APAA 4NSLA 4APBA 4BABA 2E9FA 1K7WA 3TV2A 4ADLA 4C5RA 1GK2A 2PTQA 2QGAB 3QBPA 2RJSA 4BAAA 1U16A 1TJVA 1GK3A 1TJ7A 2YIIA 4C5SA 2X75A 4EEIA 4C5UA 1T6JA 1TJUA 3E04A 1VDKA 2NYFA 1HY1A 2O6YA 3KDZA 3NZ4A 4V2QA 1TJWA 1B8FA 1J3UA 1FUQA 1GKJA 5F92A 1DCNA 2J91A 2NYNA 2PTSA 1U15A 1DOFA 1XWOA 1YFMA 1I0AA 2PFMA 4C6GA 4V2RA 5EYVA 2O7DA 3GTDA 2RJRA 1JSWA 1YFEA 3RD8A 4EFCA 2VD6A 1FUOA 4CQ5A 2O7BA 2OHYA 5F91A 5EYTA 5HW2A 2HVGA 4NLEA 1C3CA 1AUWA 2O7FA 1YISA 3OCEA 3R6YA 3RRPA 3NO9A 4FLCA 3GZHA 1FURA 4HGVA 1C3UA 3R6QA 1T6PA 1HY0A 2QVEA 1FUPA 3UNVA
chains in the Genus database with same CATH superfamily
2O7EA 3R6VA 2PTRA 4FFXA 4MX2A 2O78A 1Q5NA 3OCFA 1XL7A 1RE5A 1GKMA 3KDYA 5D6BA 1Y2MA 4ADMA 3BHGA 1W27A 3CZOA 1K62A 3C8TA 1KQ7A 1EB4A 2FUSA 4APAA 4NSLA 4APBA 4BABA 1XL8A 2E9FA 5M0JA 1K7WA 3TV2A 4ADLA 4C5RA 1GK2A 2PTQA 2QGAB 3QBPA 2RJSA 4BAAA 1U16A 1TJVA 1GK3A 1TJ7A 2YIIA 4C5SA 2X75A 4EEIA 2FELA 4C5UA 3CRW1 4A15A 1T6JA 1TJUA 3E04A 1VDKA 2NYFA 1HY1A 2O6YA 3KDZA 3NZ4A 4V2QA 1TJWA 2VSFA 1B8FA 1J3UA 2FENA 1FUQA 1GKJA 5F92A 1DCNA 2J91A 2NYNA 1XMCA 2PTSA 1U15A 1DOFA 1XWOA 1YFMA 1I0AA 1XLYA 2PFMA 4C6GA 4V2RA 5EYVA 2O7DA 3GTDA 2RJRA 1JSWA 1YFEA 3RD8A 4EFCA 2VD6A 1FUOA 4CQ5A 2O7BA 2OHYA 5F91A 2VL7A 5EYTA 5M0IA 5H8WA 3CRVA 5HW2A 2HVGA 4NLEA 1C3CA 1AUWA 2O7FA 1YISA 3OCEA 3R6YA 3RRPA 3NO9A 4FLCA 4WNLA 3GZHA 1FURA 4HGVA 1C3UA 3R6QA 1T6PA 1HY0A 1XMDA 2QVEA 1FUPA 3UNVA
chains in the Genus database with same CATH topology
2O7EA 3R6VA 2PTRA 4FFXA 4MX2A 2O78A 1Q5NA 3OCFA 1RE5A 1GKMA 3KDYA 5D6BA 1Y2MA 4ADMA 3BHGA 1W27A 3CZOA 1K62A 3C8TA 1KQ7A 1EB4A 2FUSA 4APAA 4NSLA 4APBA 4BABA 2E9FA 1K7WA 3TV2A 4ADLA 4C5RA 1GK2A 2PTQA 2QGAB 3QBPA 2RJSA 4BAAA 1U16A 1TJVA 1GK3A 1TJ7A 2YIIA 4C5SA 2X75A 4EEIA 4C5UA 1T6JA 1TJUA 3E04A 1VDKA 2NYFA 1HY1A 2O6YA 3KDZA 3NZ4A 4V2QA 1TJWA 1B8FA 1J3UA 1FUQA 1GKJA 5F92A 1DCNA 2J91A 2NYNA 2PTSA 1U15A 1DOFA 1XWOA 1YFMA 1I0AA 2PFMA 4C6GA 4V2RA 5EYVA 2O7DA 3GTDA 2RJRA 1JSWA 1YFEA 3RD8A 4EFCA 2VD6A 1FUOA 4CQ5A 2O7BA 2OHYA 5F91A 5EYTA 5HW2A 2HVGA 4NLEA 1C3CA 1AUWA 2O7FA 1YISA 3OCEA 3R6YA 3RRPA 3NO9A 4FLCA 3GZHA 1FURA 4HGVA 1C3UA 3R6QA 1T6PA 1HY0A 2QVEA 1FUPA 3UNVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O7E A;  3R6V A;  2PTR A;  4FFX A;  4MX2 A;  2O78 A;  1Q5N A;  3OCF A;  1RE5 A;  1GKM A;  3KDY A;  5D6B A;  1Y2M A;  4ADM A;  3BHG A;  1W27 A;  3CZO A;  1K62 A;  3C8T A;  1KQ7 A;  1EB4 A;  2FUS A;  4APA A;  4NSL A;  4APB A;  4BAB A;  2E9F A;  1K7W A;  3TV2 A;  4ADL A;  4C5R A;  1GK2 A;  2PTQ A;  2QGA B;  3QBP A;  2RJS A;  4BAA A;  1U16 A;  1TJV A;  1GK3 A;  1TJ7 A;  2YII A;  4C5S A;  2X75 A;  4EEI A;  4C5U A;  1T6J A;  1TJU A;  3E04 A;  1VDK A;  2NYF A;  1HY1 A;  2O6Y A;  3KDZ A;  3NZ4 A;  4V2Q A;  1TJW A;  1B8F A;  1J3U A;  1FUQ A;  1GKJ A;  5F92 A;  1DCN A;  2J91 A;  2NYN A;  2PTS A;  1U15 A;  1DOF A;  1XWO A;  1YFM A;  1I0A A;  2PFM A;  4C6G A;  4V2R A;  5EYV A;  2O7D A;  3GTD A;  2RJR A;  1JSW A;  1YFE A;  3RD8 A;  4EFC A;  2VD6 A;  1FUO A;  4CQ5 A;  2O7B A;  2OHY A;  5F91 A;  5EYT A;  5HW2 A;  2HVG A;  4NLE A;  1C3C A;  1AUW A;  2O7F A;  1YIS A;  3OCE A;  3R6Y A;  3RRP A;  3NO9 A;  4FLC A;  3GZH A;  1FUR A;  4HGV A;  1C3U A;  3R6Q A;  1T6P A;  1HY0 A;  2QVE A;  1FUP A;  3UNV A; 
#chains in the Genus database with same CATH topology
 2O7E A;  3R6V A;  2PTR A;  4FFX A;  4MX2 A;  2O78 A;  1Q5N A;  3OCF A;  1XL7 A;  1RE5 A;  1GKM A;  3KDY A;  5D6B A;  1Y2M A;  4ADM A;  3BHG A;  1W27 A;  3CZO A;  1K62 A;  3C8T A;  1KQ7 A;  1EB4 A;  2FUS A;  4APA A;  4NSL A;  4APB A;  4BAB A;  1XL8 A;  2E9F A;  5M0J A;  1K7W A;  3TV2 A;  4ADL A;  4C5R A;  1GK2 A;  2PTQ A;  2QGA B;  3QBP A;  2RJS A;  4BAA A;  1U16 A;  1TJV A;  1GK3 A;  1TJ7 A;  2YII A;  4C5S A;  2X75 A;  4EEI A;  2FEL A;  4C5U A;  3CRW 1;  4A15 A;  1T6J A;  1TJU A;  3E04 A;  1VDK A;  2NYF A;  1HY1 A;  2O6Y A;  3KDZ A;  3NZ4 A;  4V2Q A;  1TJW A;  2VSF A;  1B8F A;  1J3U A;  2FEN A;  1FUQ A;  1GKJ A;  5F92 A;  1DCN A;  2J91 A;  2NYN A;  1XMC A;  2PTS A;  1U15 A;  1DOF A;  1XWO A;  1YFM A;  1I0A A;  1XLY A;  2PFM A;  4C6G A;  4V2R A;  5EYV A;  2O7D A;  3GTD A;  2RJR A;  1JSW A;  1YFE A;  3RD8 A;  4EFC A;  2VD6 A;  1FUO A;  4CQ5 A;  2O7B A;  2OHY A;  5F91 A;  2VL7 A;  5EYT A;  5M0I A;  5H8W A;  3CRV A;  5HW2 A;  2HVG A;  4NLE A;  1C3C A;  1AUW A;  2O7F A;  1YIS A;  3OCE A;  3R6Y A;  3RRP A;  3NO9 A;  4FLC A;  4WNL A;  3GZH A;  1FUR A;  4HGV A;  1C3U A;  3R6Q A;  1T6P A;  1HY0 A;  1XMD A;  2QVE A;  1FUP A;  3UNV A; 
#chains in the Genus database with same CATH homology
 2O7E A;  3R6V A;  2PTR A;  4FFX A;  4MX2 A;  2O78 A;  1Q5N A;  3OCF A;  1RE5 A;  1GKM A;  3KDY A;  5D6B A;  1Y2M A;  4ADM A;  3BHG A;  1W27 A;  3CZO A;  1K62 A;  3C8T A;  1KQ7 A;  1EB4 A;  2FUS A;  4APA A;  4NSL A;  4APB A;  4BAB A;  2E9F A;  1K7W A;  3TV2 A;  4ADL A;  4C5R A;  1GK2 A;  2PTQ A;  2QGA B;  3QBP A;  2RJS A;  4BAA A;  1U16 A;  1TJV A;  1GK3 A;  1TJ7 A;  2YII A;  4C5S A;  2X75 A;  4EEI A;  4C5U A;  1T6J A;  1TJU A;  3E04 A;  1VDK A;  2NYF A;  1HY1 A;  2O6Y A;  3KDZ A;  3NZ4 A;  4V2Q A;  1TJW A;  1B8F A;  1J3U A;  1FUQ A;  1GKJ A;  5F92 A;  1DCN A;  2J91 A;  2NYN A;  2PTS A;  1U15 A;  1DOF A;  1XWO A;  1YFM A;  1I0A A;  2PFM A;  4C6G A;  4V2R A;  5EYV A;  2O7D A;  3GTD A;  2RJR A;  1JSW A;  1YFE A;  3RD8 A;  4EFC A;  2VD6 A;  1FUO A;  4CQ5 A;  2O7B A;  2OHY A;  5F91 A;  5EYT A;  5HW2 A;  2HVG A;  4NLE A;  1C3C A;  1AUW A;  2O7F A;  1YIS A;  3OCE A;  3R6Y A;  3RRP A;  3NO9 A;  4FLC A;  3GZH A;  1FUR A;  4HGV A;  1C3U A;  3R6Q A;  1T6P A;  1HY0 A;  2QVE A;  1FUP A;  3UNV A; 
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