1GK2A

Histidine ammonia-lyase (hal) mutant f329g from pseudomonas putida
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
509
structure length
509
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNGHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords HISTIDINE AMMONIA-LYASE
publication title Autocatalytic Peptide Cyclization During Chain Folding of Histidine Ammonia-Lyase.
pubmed doi rcsb
source organism Pseudomonas putida
molecule tags Lyase
total genus 194
structure length 509
sequence length 509
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gk2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gk2A02
4C5SA 2FUSA 5F91A 1TJUA 2NYNA 2QVEA 3KDZA 5D6BA 1J3UA 1TJVA 2PFMA 4C5RA 1XWOA 1JSWA 1GK2A 1W27A 4C6GA 3R6QA 1VDKA 4CQ5A 1Q5NA 1KQ7A 1U16A 2HVGA 3C8TA 4FFXA 2PTQA 2O7DA 4HGVA 2OHYA 2O7BA 5EYTA 1FUQA 2X75A 1HY1A 1T6PA 2PTSA 1DOFA 4FLCA 4EFCA 1T6JA 5EYVA 3E04A 1Y2MA 2J91A 1HY0A 1EB4A 2NYFA 1C3UA 1TJ7A 2O7EA 1B8FA 1U15A 4NLEA 1K7WA 4BABA 3NZ4A 4APAA 5HW2A 1TJWA 3KDYA 2YIIA 3RD8A 4NSLA 3RRPA 3UNVA 4ADMA 4APBA 4C5UA 4MX2A 2PTRA 3TV2A 1I0AA 2RJRA 3BHGA 1YFEA 2O7FA 4EEIA 1C3CA 1GKMA 1FUPA 2O78A 3OCFA 2VD6A 3QBPA 3CZOA 3GZHA 4V2QA 2O6YA 1RE5A 1DCNA 3R6VA 3R6YA 1YFMA 1AUWA 4BAAA 1GKJA 1K62A 2QGAB 1YISA 1FURA 3GTDA 4V2RA 1GK3A 3OCEA 5F92A 2RJSA 2E9FA 1FUOA 4ADLA 3NO9A
chains in the Genus database with same CATH superfamily
4C5SA 2FUSA 2FELA 5F91A 1TJUA 2FENA 2NYNA 2QVEA 1XL8A 3KDZA 5D6BA 1J3UA 1TJVA 2PFMA 4C5RA 1XWOA 1JSWA 1GK2A 1W27A 5H8WA 4C6GA 3R6QA 1VDKA 4CQ5A 1Q5NA 1KQ7A 1U16A 2VL7A 3CRW1 2HVGA 3C8TA 4FFXA 2PTQA 2O7DA 4HGVA 2OHYA 2O7BA 5EYTA 1FUQA 2X75A 1HY1A 1T6PA 2PTSA 1DOFA 4FLCA 4EFCA 1T6JA 5EYVA 3E04A 1Y2MA 2J91A 1HY0A 1EB4A 2NYFA 1C3UA 1TJ7A 2O7EA 1B8FA 1U15A 4NLEA 1K7WA 4BABA 3NZ4A 4APAA 5HW2A 1TJWA 3KDYA 2YIIA 3RD8A 1XL7A 4NSLA 3RRPA 3UNVA 4ADMA 4APBA 4C5UA 4MX2A 2PTRA 3TV2A 1I0AA 2RJRA 3BHGA 1YFEA 2O7FA 4EEIA 1C3CA 1GKMA 1XLYA 1FUPA 2O78A 3OCFA 2VD6A 3QBPA 3CZOA 3GZHA 4V2QA 2O6YA 4A15A 1RE5A 1DCNA 4WNLA 1XMCA 3R6VA 3R6YA 3CRVA 1YFMA 1AUWA 5M0IA 4BAAA 1GKJA 1K62A 2QGAB 1YISA 1FURA 1XMDA 3GTDA 4V2RA 1GK3A 3OCEA 2VSFA 5F92A 2RJSA 2E9FA 1FUOA 5M0JA 4ADLA 3NO9A
chains in the Genus database with same CATH topology
4C5SA 2FUSA 5F91A 1TJUA 2NYNA 2QVEA 3KDZA 5D6BA 1J3UA 1TJVA 2PFMA 4C5RA 1XWOA 1JSWA 1GK2A 1W27A 4C6GA 3R6QA 1VDKA 4CQ5A 1Q5NA 1KQ7A 1U16A 2HVGA 3C8TA 4FFXA 2PTQA 2O7DA 4HGVA 2OHYA 2O7BA 5EYTA 1FUQA 2X75A 1HY1A 1T6PA 2PTSA 1DOFA 4FLCA 4EFCA 1T6JA 5EYVA 3E04A 1Y2MA 2J91A 1HY0A 1EB4A 2NYFA 1C3UA 1TJ7A 2O7EA 1B8FA 1U15A 4NLEA 1K7WA 4BABA 3NZ4A 4APAA 5HW2A 1TJWA 3KDYA 2YIIA 3RD8A 4NSLA 3RRPA 3UNVA 4ADMA 4APBA 4C5UA 4MX2A 2PTRA 3TV2A 1I0AA 2RJRA 3BHGA 1YFEA 2O7FA 4EEIA 1C3CA 1GKMA 1FUPA 2O78A 3OCFA 2VD6A 3QBPA 3CZOA 3GZHA 4V2QA 2O6YA 1RE5A 1DCNA 3R6VA 3R6YA 1YFMA 1AUWA 4BAAA 1GKJA 1K62A 2QGAB 1YISA 1FURA 3GTDA 4V2RA 1GK3A 3OCEA 5F92A 2RJSA 2E9FA 1FUOA 4ADLA 3NO9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5S A;  2FUS A;  5F91 A;  1TJU A;  2NYN A;  2QVE A;  3KDZ A;  5D6B A;  1J3U A;  1TJV A;  2PFM A;  4C5R A;  1XWO A;  1JSW A;  1GK2 A;  1W27 A;  4C6G A;  3R6Q A;  1VDK A;  4CQ5 A;  1Q5N A;  1KQ7 A;  1U16 A;  2HVG A;  3C8T A;  4FFX A;  2PTQ A;  2O7D A;  4HGV A;  2OHY A;  2O7B A;  5EYT A;  1FUQ A;  2X75 A;  1HY1 A;  1T6P A;  2PTS A;  1DOF A;  4FLC A;  4EFC A;  1T6J A;  5EYV A;  3E04 A;  1Y2M A;  2J91 A;  1HY0 A;  1EB4 A;  2NYF A;  1C3U A;  1TJ7 A;  2O7E A;  1B8F A;  1U15 A;  4NLE A;  1K7W A;  4BAB A;  3NZ4 A;  4APA A;  5HW2 A;  1TJW A;  3KDY A;  2YII A;  3RD8 A;  4NSL A;  3RRP A;  3UNV A;  4ADM A;  4APB A;  4C5U A;  4MX2 A;  2PTR A;  3TV2 A;  1I0A A;  2RJR A;  3BHG A;  1YFE A;  2O7F A;  4EEI A;  1C3C A;  1GKM A;  1FUP A;  2O78 A;  3OCF A;  2VD6 A;  3QBP A;  3CZO A;  3GZH A;  4V2Q A;  2O6Y A;  1RE5 A;  1DCN A;  3R6V A;  3R6Y A;  1YFM A;  1AUW A;  4BAA A;  1GKJ A;  1K62 A;  2QGA B;  1YIS A;  1FUR A;  3GTD A;  4V2R A;  1GK3 A;  3OCE A;  5F92 A;  2RJS A;  2E9F A;  1FUO A;  4ADL A;  3NO9 A; 
#chains in the Genus database with same CATH topology
 4C5S A;  2FUS A;  2FEL A;  5F91 A;  1TJU A;  2FEN A;  2NYN A;  2QVE A;  1XL8 A;  3KDZ A;  5D6B A;  1J3U A;  1TJV A;  2PFM A;  4C5R A;  1XWO A;  1JSW A;  1GK2 A;  1W27 A;  5H8W A;  4C6G A;  3R6Q A;  1VDK A;  4CQ5 A;  1Q5N A;  1KQ7 A;  1U16 A;  2VL7 A;  3CRW 1;  2HVG A;  3C8T A;  4FFX A;  2PTQ A;  2O7D A;  4HGV A;  2OHY A;  2O7B A;  5EYT A;  1FUQ A;  2X75 A;  1HY1 A;  1T6P A;  2PTS A;  1DOF A;  4FLC A;  4EFC A;  1T6J A;  5EYV A;  3E04 A;  1Y2M A;  2J91 A;  1HY0 A;  1EB4 A;  2NYF A;  1C3U A;  1TJ7 A;  2O7E A;  1B8F A;  1U15 A;  4NLE A;  1K7W A;  4BAB A;  3NZ4 A;  4APA A;  5HW2 A;  1TJW A;  3KDY A;  2YII A;  3RD8 A;  1XL7 A;  4NSL A;  3RRP A;  3UNV A;  4ADM A;  4APB A;  4C5U A;  4MX2 A;  2PTR A;  3TV2 A;  1I0A A;  2RJR A;  3BHG A;  1YFE A;  2O7F A;  4EEI A;  1C3C A;  1GKM A;  1XLY A;  1FUP A;  2O78 A;  3OCF A;  2VD6 A;  3QBP A;  3CZO A;  3GZH A;  4V2Q A;  2O6Y A;  4A15 A;  1RE5 A;  1DCN A;  4WNL A;  1XMC A;  3R6V A;  3R6Y A;  3CRV A;  1YFM A;  1AUW A;  5M0I A;  4BAA A;  1GKJ A;  1K62 A;  2QGA B;  1YIS A;  1FUR A;  1XMD A;  3GTD A;  4V2R A;  1GK3 A;  3OCE A;  2VSF A;  5F92 A;  2RJS A;  2E9F A;  1FUO A;  5M0J A;  4ADL A;  3NO9 A; 
#chains in the Genus database with same CATH homology
 4C5S A;  2FUS A;  5F91 A;  1TJU A;  2NYN A;  2QVE A;  3KDZ A;  5D6B A;  1J3U A;  1TJV A;  2PFM A;  4C5R A;  1XWO A;  1JSW A;  1GK2 A;  1W27 A;  4C6G A;  3R6Q A;  1VDK A;  4CQ5 A;  1Q5N A;  1KQ7 A;  1U16 A;  2HVG A;  3C8T A;  4FFX A;  2PTQ A;  2O7D A;  4HGV A;  2OHY A;  2O7B A;  5EYT A;  1FUQ A;  2X75 A;  1HY1 A;  1T6P A;  2PTS A;  1DOF A;  4FLC A;  4EFC A;  1T6J A;  5EYV A;  3E04 A;  1Y2M A;  2J91 A;  1HY0 A;  1EB4 A;  2NYF A;  1C3U A;  1TJ7 A;  2O7E A;  1B8F A;  1U15 A;  4NLE A;  1K7W A;  4BAB A;  3NZ4 A;  4APA A;  5HW2 A;  1TJW A;  3KDY A;  2YII A;  3RD8 A;  4NSL A;  3RRP A;  3UNV A;  4ADM A;  4APB A;  4C5U A;  4MX2 A;  2PTR A;  3TV2 A;  1I0A A;  2RJR A;  3BHG A;  1YFE A;  2O7F A;  4EEI A;  1C3C A;  1GKM A;  1FUP A;  2O78 A;  3OCF A;  2VD6 A;  3QBP A;  3CZO A;  3GZH A;  4V2Q A;  2O6Y A;  1RE5 A;  1DCN A;  3R6V A;  3R6Y A;  1YFM A;  1AUW A;  4BAA A;  1GKJ A;  1K62 A;  2QGA B;  1YIS A;  1FUR A;  3GTD A;  4V2R A;  1GK3 A;  3OCE A;  5F92 A;  2RJS A;  2E9F A;  1FUO A;  4ADL A;  3NO9 A; 
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