1GK2A

Histidine ammonia-lyase (hal) mutant f329g from pseudomonas putida
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
509
structure length
509
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNGHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords HISTIDINE AMMONIA-LYASE
publication title Autocatalytic Peptide Cyclization During Chain Folding of Histidine Ammonia-Lyase.
pubmed doi rcsb
source organism Pseudomonas putida
total genus 194
structure length 509
sequence length 509
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gk2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gk2A02
2NYNA 2X75A 4BABA 1TJWA 4NLEA 1YISA 2NYFA 1DOFA 2O7DA 3NO9A 2VD6A 4APAA 1KQ7A 1GKMA 1YFEA 3OCEA 1U16A 1Y2MA 3KDYA 3RRPA 1GK3A 4FLCA 2O7FA 3QBPA 1FURA 1C3UA 1K62A 4V2QA 3E04A 3TV2A 4CQ5A 1FUPA 4NSLA 5EYTA 2FUSA 2J91A 4C6GA 3R6QA 2O7EA 2QGAB 1TJUA 1HY0A 4BAAA 1T6PA 3C8TA 3RD8A 5EYVA 1K7WA 2PTSA 2QVEA 2YIIA 1TJVA 3BHGA 1T6JA 4APBA 4C5SA 2PTRA 3R6VA 3R6YA 1AUWA 5D6BA 2O6YA 1JSWA 4EEIA 4V2RA 5HW2A 4HGVA 4ADMA 4C5UA 1Q5NA 1W27A 1TJ7A 2O7BA 4EFCA 1J3UA 1GK2A 5F92A 1XWOA 1RE5A 1I0AA 4C5RA 2O78A 2PTQA 2OHYA 3CZOA 3OCFA 3GZHA 1B8FA 1C3CA 1VDKA 3KDZA 1U15A 1EB4A 1DCNA 5F91A 2PFMA 3NZ4A 2HVGA 2RJRA 2E9FA 3UNVA 1HY1A 4FFXA 1FUQA 2RJSA 4MX2A 1GKJA 1YFMA 3GTDA 4ADLA 1FUOA
chains in the Genus database with same CATH superfamily
2NYNA 2X75A 4BABA 1TJWA 4NLEA 1YISA 2NYFA 1DOFA 2O7DA 1XLYA 3NO9A 2VD6A 4APAA 1KQ7A 1GKMA 1YFEA 3OCEA 2FENA 1U16A 1Y2MA 3KDYA 3RRPA 2VSFA 1GK3A 4FLCA 2O7FA 3QBPA 1FURA 1C3UA 1K62A 4V2QA 3E04A 3TV2A 4CQ5A 1FUPA 4NSLA 1XMCA 5EYTA 2FUSA 2J91A 4A15A 4C6GA 3R6QA 4WNLA 2O7EA 2QGAB 1TJUA 5H8WA 1HY0A 4BAAA 1T6PA 3CRW1 1XL7A 3C8TA 3RD8A 5EYVA 1K7WA 2PTSA 2QVEA 2YIIA 1TJVA 3BHGA 1T6JA 4APBA 3CRVA 4C5SA 2PTRA 3R6VA 3R6YA 1AUWA 5D6BA 2O6YA 1JSWA 4EEIA 4V2RA 5HW2A 4HGVA 4ADMA 4C5UA 1Q5NA 1W27A 1TJ7A 5M0JA 2O7BA 4EFCA 1XL8A 1J3UA 1GK2A 5F92A 1XWOA 1RE5A 1I0AA 4C5RA 2O78A 2PTQA 2OHYA 3CZOA 3OCFA 3GZHA 1B8FA 1C3CA 1VDKA 3KDZA 2VL7A 1U15A 1EB4A 1DCNA 5F91A 2PFMA 3NZ4A 2HVGA 2RJRA 2E9FA 3UNVA 1HY1A 4FFXA 1FUQA 5M0IA 2RJSA 1XMDA 2FELA 4MX2A 1GKJA 1YFMA 3GTDA 4ADLA 1FUOA
chains in the Genus database with same CATH topology
2NYNA 2X75A 4BABA 1TJWA 4NLEA 1YISA 2NYFA 1DOFA 2O7DA 3NO9A 2VD6A 4APAA 1KQ7A 1GKMA 1YFEA 3OCEA 1U16A 1Y2MA 3KDYA 3RRPA 1GK3A 4FLCA 2O7FA 3QBPA 1FURA 1C3UA 1K62A 4V2QA 3E04A 3TV2A 4CQ5A 1FUPA 4NSLA 5EYTA 2FUSA 2J91A 4C6GA 3R6QA 2O7EA 2QGAB 1TJUA 1HY0A 4BAAA 1T6PA 3C8TA 3RD8A 5EYVA 1K7WA 2PTSA 2QVEA 2YIIA 1TJVA 3BHGA 1T6JA 4APBA 4C5SA 2PTRA 3R6VA 3R6YA 1AUWA 5D6BA 2O6YA 1JSWA 4EEIA 4V2RA 5HW2A 4HGVA 4ADMA 4C5UA 1Q5NA 1W27A 1TJ7A 2O7BA 4EFCA 1J3UA 1GK2A 5F92A 1XWOA 1RE5A 1I0AA 4C5RA 2O78A 2PTQA 2OHYA 3CZOA 3OCFA 3GZHA 1B8FA 1C3CA 1VDKA 3KDZA 1U15A 1EB4A 1DCNA 5F91A 2PFMA 3NZ4A 2HVGA 2RJRA 2E9FA 3UNVA 1HY1A 4FFXA 1FUQA 2RJSA 4MX2A 1GKJA 1YFMA 3GTDA 4ADLA 1FUOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYN A;  2X75 A;  4BAB A;  1TJW A;  4NLE A;  1YIS A;  2NYF A;  1DOF A;  2O7D A;  3NO9 A;  2VD6 A;  4APA A;  1KQ7 A;  1GKM A;  1YFE A;  3OCE A;  1U16 A;  1Y2M A;  3KDY A;  3RRP A;  1GK3 A;  4FLC A;  2O7F A;  3QBP A;  1FUR A;  1C3U A;  1K62 A;  4V2Q A;  3E04 A;  3TV2 A;  4CQ5 A;  1FUP A;  4NSL A;  5EYT A;  2FUS A;  2J91 A;  4C6G A;  3R6Q A;  2O7E A;  2QGA B;  1TJU A;  1HY0 A;  4BAA A;  1T6P A;  3C8T A;  3RD8 A;  5EYV A;  1K7W A;  2PTS A;  2QVE A;  2YII A;  1TJV A;  3BHG A;  1T6J A;  4APB A;  4C5S A;  2PTR A;  3R6V A;  3R6Y A;  1AUW A;  5D6B A;  2O6Y A;  1JSW A;  4EEI A;  4V2R A;  5HW2 A;  4HGV A;  4ADM A;  4C5U A;  1Q5N A;  1W27 A;  1TJ7 A;  2O7B A;  4EFC A;  1J3U A;  1GK2 A;  5F92 A;  1XWO A;  1RE5 A;  1I0A A;  4C5R A;  2O78 A;  2PTQ A;  2OHY A;  3CZO A;  3OCF A;  3GZH A;  1B8F A;  1C3C A;  1VDK A;  3KDZ A;  1U15 A;  1EB4 A;  1DCN A;  5F91 A;  2PFM A;  3NZ4 A;  2HVG A;  2RJR A;  2E9F A;  3UNV A;  1HY1 A;  4FFX A;  1FUQ A;  2RJS A;  4MX2 A;  1GKJ A;  1YFM A;  3GTD A;  4ADL A;  1FUO A; 
#chains in the Genus database with same CATH topology
 2NYN A;  2X75 A;  4BAB A;  1TJW A;  4NLE A;  1YIS A;  2NYF A;  1DOF A;  2O7D A;  1XLY A;  3NO9 A;  2VD6 A;  4APA A;  1KQ7 A;  1GKM A;  1YFE A;  3OCE A;  2FEN A;  1U16 A;  1Y2M A;  3KDY A;  3RRP A;  2VSF A;  1GK3 A;  4FLC A;  2O7F A;  3QBP A;  1FUR A;  1C3U A;  1K62 A;  4V2Q A;  3E04 A;  3TV2 A;  4CQ5 A;  1FUP A;  4NSL A;  1XMC A;  5EYT A;  2FUS A;  2J91 A;  4A15 A;  4C6G A;  3R6Q A;  4WNL A;  2O7E A;  2QGA B;  1TJU A;  5H8W A;  1HY0 A;  4BAA A;  1T6P A;  3CRW 1;  1XL7 A;  3C8T A;  3RD8 A;  5EYV A;  1K7W A;  2PTS A;  2QVE A;  2YII A;  1TJV A;  3BHG A;  1T6J A;  4APB A;  3CRV A;  4C5S A;  2PTR A;  3R6V A;  3R6Y A;  1AUW A;  5D6B A;  2O6Y A;  1JSW A;  4EEI A;  4V2R A;  5HW2 A;  4HGV A;  4ADM A;  4C5U A;  1Q5N A;  1W27 A;  1TJ7 A;  5M0J A;  2O7B A;  4EFC A;  1XL8 A;  1J3U A;  1GK2 A;  5F92 A;  1XWO A;  1RE5 A;  1I0A A;  4C5R A;  2O78 A;  2PTQ A;  2OHY A;  3CZO A;  3OCF A;  3GZH A;  1B8F A;  1C3C A;  1VDK A;  3KDZ A;  2VL7 A;  1U15 A;  1EB4 A;  1DCN A;  5F91 A;  2PFM A;  3NZ4 A;  2HVG A;  2RJR A;  2E9F A;  3UNV A;  1HY1 A;  4FFX A;  1FUQ A;  5M0I A;  2RJS A;  1XMD A;  2FEL A;  4MX2 A;  1GKJ A;  1YFM A;  3GTD A;  4ADL A;  1FUO A; 
#chains in the Genus database with same CATH homology
 2NYN A;  2X75 A;  4BAB A;  1TJW A;  4NLE A;  1YIS A;  2NYF A;  1DOF A;  2O7D A;  3NO9 A;  2VD6 A;  4APA A;  1KQ7 A;  1GKM A;  1YFE A;  3OCE A;  1U16 A;  1Y2M A;  3KDY A;  3RRP A;  1GK3 A;  4FLC A;  2O7F A;  3QBP A;  1FUR A;  1C3U A;  1K62 A;  4V2Q A;  3E04 A;  3TV2 A;  4CQ5 A;  1FUP A;  4NSL A;  5EYT A;  2FUS A;  2J91 A;  4C6G A;  3R6Q A;  2O7E A;  2QGA B;  1TJU A;  1HY0 A;  4BAA A;  1T6P A;  3C8T A;  3RD8 A;  5EYV A;  1K7W A;  2PTS A;  2QVE A;  2YII A;  1TJV A;  3BHG A;  1T6J A;  4APB A;  4C5S A;  2PTR A;  3R6V A;  3R6Y A;  1AUW A;  5D6B A;  2O6Y A;  1JSW A;  4EEI A;  4V2R A;  5HW2 A;  4HGV A;  4ADM A;  4C5U A;  1Q5N A;  1W27 A;  1TJ7 A;  2O7B A;  4EFC A;  1J3U A;  1GK2 A;  5F92 A;  1XWO A;  1RE5 A;  1I0A A;  4C5R A;  2O78 A;  2PTQ A;  2OHY A;  3CZO A;  3OCF A;  3GZH A;  1B8F A;  1C3C A;  1VDK A;  3KDZ A;  1U15 A;  1EB4 A;  1DCN A;  5F91 A;  2PFM A;  3NZ4 A;  2HVG A;  2RJR A;  2E9F A;  3UNV A;  1HY1 A;  4FFX A;  1FUQ A;  2RJS A;  4MX2 A;  1GKJ A;  1YFM A;  3GTD A;  4ADL A;  1FUO A; 
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