4HGVA

Crystal structure of a fumarate hydratase
Total Genus 158
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
sequence length
461
structure length
456
Chain Sequence
b'STRTETDTFGPIEVASDRYWGAQAQRSLGNFKIGWEKQPLAIVRALGIVKQAAARANMALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLGGVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFDHIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAPVGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLGSGPRSGLGELSLPENEPGSKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELNVYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYDNAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGPA'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Fumarate hydratase class II
publication title Crystal structure of a fumarate hydratase
rcsb
source organism Sinorhizobium meliloti
molecule tags Lyase
total genus 158
structure length 456
sequence length 461
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4hgvA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4hgvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4hgvA02
3UNVA 1U15A 1FUOA 4C5UA 3E04A 1FUPA 2NYFA 1DCNA 3OCFA 1K62A 3TV2A 2O7DA 2FUSA 1RE5A 1FURA 4FFXA 1TJUA 3OCEA 4C5RA 3NO9A 4EEIA 2PTSA 4V2QA 3C8TA 3GZHA 1YFMA 2PTQA 1GKMA 3RRPA 3R6VA 2VD6A 3R6QA 2PTRA 4C6GA 1C3CA 1U16A 4HGVA 4APAA 1Y2MA 2O7EA 4V2RA 3BHGA 2O78A 4APBA 4EFCA 1HY1A 4FLCA 4BAAA 1GK3A 2HVGA 2X75A 2RJRA 2PFMA 4NSLA 3KDZA 1KQ7A 3GTDA 1VDKA 1K7WA 1TJWA 1JSWA 5F92A 5F91A 4ADMA 5HW2A 1YFEA 1DOFA 3QBPA 1J3UA 2O7FA 2YIIA 2O7BA 1TJVA 1FUQA 1TJ7A 4ADLA 4C5SA 2OHYA 2QGAB 4CQ5A 1I0AA 1GK2A 1XWOA 1W27A 5D6BA 2E9FA 1YISA 1AUWA 2RJSA 3KDYA 2NYNA 3CZOA 1GKJA 3RD8A 2J91A 1EB4A 2QVEA 3NZ4A 1T6JA 5EYTA 4NLEA 1T6PA 4MX2A 1Q5NA 1HY0A 2O6YA 5EYVA 4BABA 1C3UA 1B8FA 3R6YA
chains in the Genus database with same CATH superfamily
1IW7D 3UNVA 1U15A 1FUOA 4C5UA 3E04A 1FUPA 3CI0K 1XL8A 2NYFA 1DCNA 3OCFA 4E88A 1K62A 3U19A 3TV2A 2RCNA 2O7DA 2FUSA 1RE5A 1Z4JA 1FURA 2JARA 1T9HA 4FFXA 1TJUA 3OCEA 4C5RA 5M0IA 3NO9A 4EEIA 2PTSA 1XL7A 4V2QA 3C8TA 3GZHA 1YFMA 2PTQA 1GKMA 1Q92A 3RRPA 3R6VA 2VD6A 3R6QA 2FELA 2PTRA 2JAWA 4C6GA 1C3CA 1U16A 4HGVA 4APAA 1Y2MA 3CRW1 2O7EA 4V2RA 3BHGA 2O78A 4APBA 1U0LA 4NFLA 3F4RA 4YIHA 4YIKA 4L6CA 4EFCA 2VSFA 2FENA 5M0JA 1HY1A 1XMCA 4FLCA 4BAAA 1GK3A 2HVGA 2I7DA 1Z4IA 2JAUA 2X75A 2RJRA 2PFMA 3F4SA 4NSLA 3KDZA 4MUMA 1KQ7A 3GTDA 1VDKA 3F4TA 1K7WA 1TJWA 2VL7A 1JSWA 1XMDA 5F92A 5F91A 1Z4LA 4ADMA 5HW2A 1YFEA 1DOFA 1Q91A 4L57A 1MH9A 3QBPA 1J3UA 2O7FA 2YIIA 2O7BA 1TJVA 1Z4MA 2D28C 1FUQA 1TJ7A 4ADLA 4C5SA 1Z4KA 1Z4QA 4L6AA 3U13A 1XLYA 2OHYA 2QGAB 4CQ5A 3CRVA 1I0AA 1GK2A 1XWOA 4MWOA 5D6BA 2E9FA 1W27A 1YISA 5H8WA 1AUWA 2YV5A 2RJSA 2D27A 2NYNA 3CZOA 3KDYA 1GKJA 4IQJM 3RD8A 2J91A 4WNLA 1EB4A 2QVEA 3NZ4A 1Z4PX 1T6JA 4NLEA 1T6PA 5EYTA 4A15A 4MX2A 1Q5NA 1HY0A 2O6YA 5EYVA 4BABA 1C3UA 1B8FA 3BWVA 2JAOA 3R6YA
chains in the Genus database with same CATH topology
3UNVA 1U15A 1FUOA 4C5UA 3E04A 1FUPA 2NYFA 1DCNA 3OCFA 1K62A 3TV2A 2O7DA 2FUSA 1RE5A 1FURA 4FFXA 1TJUA 3OCEA 4C5RA 3NO9A 4EEIA 2PTSA 4V2QA 3C8TA 3GZHA 1YFMA 2PTQA 1GKMA 3RRPA 3R6VA 2VD6A 3R6QA 2PTRA 4C6GA 1C3CA 1U16A 4HGVA 4APAA 1Y2MA 2O7EA 4V2RA 3BHGA 2O78A 4APBA 4EFCA 1HY1A 4FLCA 4BAAA 1GK3A 2HVGA 2X75A 2RJRA 2PFMA 4NSLA 3KDZA 1KQ7A 3GTDA 1VDKA 1K7WA 1TJWA 1JSWA 5F92A 5F91A 4ADMA 5HW2A 1YFEA 1DOFA 3QBPA 1J3UA 2O7FA 2YIIA 2O7BA 1TJVA 1FUQA 1TJ7A 4ADLA 4C5SA 2OHYA 2QGAB 4CQ5A 1I0AA 1GK2A 1XWOA 1W27A 5D6BA 2E9FA 1YISA 1AUWA 2RJSA 3KDYA 2NYNA 3CZOA 1GKJA 3RD8A 2J91A 1EB4A 2QVEA 3NZ4A 1T6JA 5EYTA 4NLEA 1T6PA 4MX2A 1Q5NA 1HY0A 2O6YA 5EYVA 4BABA 1C3UA 1B8FA 3R6YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UNV A;  1U15 A;  1FUO A;  4C5U A;  3E04 A;  1FUP A;  2NYF A;  1DCN A;  3OCF A;  1K62 A;  3TV2 A;  2O7D A;  2FUS A;  1RE5 A;  1FUR A;  4FFX A;  1TJU A;  3OCE A;  4C5R A;  3NO9 A;  4EEI A;  2PTS A;  4V2Q A;  3C8T A;  3GZH A;  1YFM A;  2PTQ A;  1GKM A;  3RRP A;  3R6V A;  2VD6 A;  3R6Q A;  2PTR A;  4C6G A;  1C3C A;  1U16 A;  4HGV A;  4APA A;  1Y2M A;  2O7E A;  4V2R A;  3BHG A;  2O78 A;  4APB A;  4EFC A;  1HY1 A;  4FLC A;  4BAA A;  1GK3 A;  2HVG A;  2X75 A;  2RJR A;  2PFM A;  4NSL A;  3KDZ A;  1KQ7 A;  3GTD A;  1VDK A;  1K7W A;  1TJW A;  1JSW A;  5F92 A;  5F91 A;  4ADM A;  5HW2 A;  1YFE A;  1DOF A;  3QBP A;  1J3U A;  2O7F A;  2YII A;  2O7B A;  1TJV A;  1FUQ A;  1TJ7 A;  4ADL A;  4C5S A;  2OHY A;  2QGA B;  4CQ5 A;  1I0A A;  1GK2 A;  1XWO A;  1W27 A;  5D6B A;  2E9F A;  1YIS A;  1AUW A;  2RJS A;  3KDY A;  2NYN A;  3CZO A;  1GKJ A;  3RD8 A;  2J91 A;  1EB4 A;  2QVE A;  3NZ4 A;  1T6J A;  5EYT A;  4NLE A;  1T6P A;  4MX2 A;  1Q5N A;  1HY0 A;  2O6Y A;  5EYV A;  4BAB A;  1C3U A;  1B8F A;  3R6Y A; 
#chains in the Genus database with same CATH topology
 1IW7 D;  3UNV A;  1U15 A;  1FUO A;  4C5U A;  3E04 A;  1FUP A;  3CI0 K;  1XL8 A;  2NYF A;  1DCN A;  3OCF A;  4E88 A;  1K62 A;  3U19 A;  3TV2 A;  2RCN A;  2O7D A;  2FUS A;  1RE5 A;  1Z4J A;  1FUR A;  2JAR A;  1T9H A;  4FFX A;  1TJU A;  3OCE A;  4C5R A;  5M0I A;  3NO9 A;  4EEI A;  2PTS A;  1XL7 A;  4V2Q A;  3C8T A;  3GZH A;  1YFM A;  2PTQ A;  1GKM A;  1Q92 A;  3RRP A;  3R6V A;  2VD6 A;  3R6Q A;  2FEL A;  2PTR A;  2JAW A;  4C6G A;  1C3C A;  1U16 A;  4HGV A;  4APA A;  1Y2M A;  3CRW 1;  2O7E A;  4V2R A;  3BHG A;  2O78 A;  4APB A;  1U0L A;  4NFL A;  3F4R A;  4YIH A;  4YIK A;  4L6C A;  4EFC A;  2VSF A;  2FEN A;  5M0J A;  1HY1 A;  1XMC A;  4FLC A;  4BAA A;  1GK3 A;  2HVG A;  2I7D A;  1Z4I A;  2JAU A;  2X75 A;  2RJR A;  2PFM A;  3F4S A;  4NSL A;  3KDZ A;  4MUM A;  1KQ7 A;  3GTD A;  1VDK A;  3F4T A;  1K7W A;  1TJW A;  2VL7 A;  1JSW A;  1XMD A;  5F92 A;  5F91 A;  1Z4L A;  4ADM A;  5HW2 A;  1YFE A;  1DOF A;  1Q91 A;  4L57 A;  1MH9 A;  3QBP A;  1J3U A;  2O7F A;  2YII A;  2O7B A;  1TJV A;  1Z4M A;  2D28 C;  1FUQ A;  1TJ7 A;  4ADL A;  4C5S A;  1Z4K A;  1Z4Q A;  4L6A A;  3U13 A;  1XLY A;  2OHY A;  2QGA B;  4CQ5 A;  3CRV A;  1I0A A;  1GK2 A;  1XWO A;  4MWO A;  5D6B A;  2E9F A;  1W27 A;  1YIS A;  5H8W A;  1AUW A;  2YV5 A;  2RJS A;  2D27 A;  2NYN A;  3CZO A;  3KDY A;  1GKJ A;  4IQJ M;  3RD8 A;  2J91 A;  4WNL A;  1EB4 A;  2QVE A;  3NZ4 A;  1Z4P X;  1T6J A;  4NLE A;  1T6P A;  5EYT A;  4A15 A;  4MX2 A;  1Q5N A;  1HY0 A;  2O6Y A;  5EYV A;  4BAB A;  1C3U A;  1B8F A;  3BWV A;  2JAO A;  3R6Y A; 
#chains in the Genus database with same CATH homology
 3UNV A;  1U15 A;  1FUO A;  4C5U A;  3E04 A;  1FUP A;  2NYF A;  1DCN A;  3OCF A;  1K62 A;  3TV2 A;  2O7D A;  2FUS A;  1RE5 A;  1FUR A;  4FFX A;  1TJU A;  3OCE A;  4C5R A;  3NO9 A;  4EEI A;  2PTS A;  4V2Q A;  3C8T A;  3GZH A;  1YFM A;  2PTQ A;  1GKM A;  3RRP A;  3R6V A;  2VD6 A;  3R6Q A;  2PTR A;  4C6G A;  1C3C A;  1U16 A;  4HGV A;  4APA A;  1Y2M A;  2O7E A;  4V2R A;  3BHG A;  2O78 A;  4APB A;  4EFC A;  1HY1 A;  4FLC A;  4BAA A;  1GK3 A;  2HVG A;  2X75 A;  2RJR A;  2PFM A;  4NSL A;  3KDZ A;  1KQ7 A;  3GTD A;  1VDK A;  1K7W A;  1TJW A;  1JSW A;  5F92 A;  5F91 A;  4ADM A;  5HW2 A;  1YFE A;  1DOF A;  3QBP A;  1J3U A;  2O7F A;  2YII A;  2O7B A;  1TJV A;  1FUQ A;  1TJ7 A;  4ADL A;  4C5S A;  2OHY A;  2QGA B;  4CQ5 A;  1I0A A;  1GK2 A;  1XWO A;  1W27 A;  5D6B A;  2E9F A;  1YIS A;  1AUW A;  2RJS A;  3KDY A;  2NYN A;  3CZO A;  1GKJ A;  3RD8 A;  2J91 A;  1EB4 A;  2QVE A;  3NZ4 A;  1T6J A;  5EYT A;  4NLE A;  1T6P A;  4MX2 A;  1Q5N A;  1HY0 A;  2O6Y A;  5EYV A;  4BAB A;  1C3U A;  1B8F A;  3R6Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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