4HGVA

Crystal structure of a fumarate hydratase
Total Genus 158
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
sequence length
461
structure length
456
Chain Sequence
STRTETDTFGPIEVASDRYWGAQAQRSLGNFKIGWEKQPLAIVRALGIVKQAAARANMALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLGGVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFDHIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAPVGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLGSGPRSGLGELSLPENEPGSKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELNVYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYDNAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Fumarate hydratase class II
publication title Crystal structure of a fumarate hydratase
rcsb
source organism Sinorhizobium meliloti
total genus 158
structure length 456
sequence length 461
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4hgvA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4hgvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4hgvA02
1TJ7A 1YISA 1TJWA 4ADLA 1FURA 5F91A 4C5SA 1C3UA 1K7WA 1AUWA 2RJSA 1Y2MA 3RRPA 3NO9A 2PTQA 1XWOA 4NSLA 1KQ7A 1YFMA 3R6VA 2NYNA 1YFEA 1HY0A 4C6GA 4APBA 1TJVA 4NLEA 1EB4A 3R6QA 3UNVA 3OCEA 1U15A 1T6PA 1I0AA 1FUOA 3CZOA 2VD6A 1J3UA 1T6JA 1DCNA 4BABA 2O7DA 2PTRA 2FUSA 4EEIA 4FLCA 1U16A 3GZHA 5EYTA 4V2QA 1TJUA 2QVEA 3RD8A 4C5RA 2O7BA 4CQ5A 2NYFA 2HVGA 4MX2A 1W27A 3QBPA 3TV2A 1C3CA 2QGAB 2X75A 1GK3A 2O7EA 1FUPA 5HW2A 1B8FA 1HY1A 2O78A 1K62A 2OHYA 5EYVA 1Q5NA 1RE5A 4APAA 3KDZA 2PFMA 1GKJA 2O6YA 1GK2A 4HGVA 4EFCA 4BAAA 5D6BA 3GTDA 2PTSA 3R6YA 3KDYA 2RJRA 1VDKA 2O7FA 1GKMA 3OCFA 5F92A 4ADMA 3E04A 4V2RA 4C5UA 3C8TA 2J91A 2YIIA 3NZ4A 1JSWA 4FFXA 1DOFA 2E9FA 1FUQA 3BHGA
chains in the Genus database with same CATH superfamily
1TJ7A 1Z4JA 2RCNA 1TJWA 2JAUA 1FURA 3BWVA 4ADLA 5F91A 1YISA 4C5SA 1C3UA 1K7WA 1AUWA 1XL8A 2RJSA 1Y2MA 3RRPA 1IW7D 4MWOA 3NO9A 2PTQA 3F4TA 4A15A 1XWOA 4NSLA 1KQ7A 1YFMA 3R6VA 2NYNA 1YFEA 1HY0A 4C6GA 4APBA 4NFLA 3CRVA 4YIKA 1TJVA 4NLEA 1EB4A 3R6QA 2FELA 3UNVA 3OCEA 4L6CA 4L6AA 4IQJM 1U15A 4MUMA 1T6PA 1I0AA 1FUOA 3CZOA 3CI0K 3U13A 2VD6A 1XLYA 1J3UA 1T6JA 1DCNA 4BABA 2O7DA 2VL7A 2D28C 2PTRA 2I7DA 2FUSA 4EEIA 4FLCA 1U16A 3GZHA 4YIHA 2VSFA 5EYTA 4V2QA 4WNLA 1TJUA 2YV5A 3RD8A 2QVEA 2O7BA 4C5RA 4CQ5A 4E88A 2NYFA 2HVGA 1Z4KA 4MX2A 3U19A 1W27A 3QBPA 3TV2A 1C3CA 2QGAB 2X75A 1Z4QA 1XMDA 1Z4IA 1XL7A 3F4RA 3F4SA 1GK3A 2O7EA 1FUPA 5HW2A 1Q91A 1Q92A 2D27A 1XMCA 1B8FA 5M0JA 1HY1A 2JAOA 2O78A 1K62A 2OHYA 5EYVA 5H8WA 1MH9A 1Q5NA 1T9HA 1RE5A 2JAWA 4APAA 3KDZA 2PFMA 2JARA 1Z4MA 1GKJA 2FENA 2O6YA 1GK2A 4HGVA 4EFCA 4BAAA 5D6BA 3GTDA 2PTSA 3R6YA 3KDYA 2RJRA 1VDKA 2O7FA 1GKMA 3OCFA 5F92A 3CRW1 1U0LA 4ADMA 3E04A 4V2RA 4C5UA 3C8TA 1Z4PX 2J91A 2YIIA 3NZ4A 1JSWA 4L57A 1Z4LA 4FFXA 1DOFA 2E9FA 5M0IA 1FUQA 3BHGA
chains in the Genus database with same CATH topology
1TJ7A 1YISA 1TJWA 4ADLA 1FURA 5F91A 4C5SA 1C3UA 1K7WA 1AUWA 2RJSA 1Y2MA 3RRPA 3NO9A 2PTQA 1XWOA 4NSLA 1KQ7A 1YFMA 3R6VA 2NYNA 1YFEA 1HY0A 4C6GA 4APBA 1TJVA 4NLEA 1EB4A 3R6QA 3UNVA 3OCEA 1U15A 1T6PA 1I0AA 1FUOA 3CZOA 2VD6A 1J3UA 1T6JA 1DCNA 4BABA 2O7DA 2PTRA 2FUSA 4EEIA 4FLCA 1U16A 3GZHA 5EYTA 4V2QA 1TJUA 2QVEA 3RD8A 4C5RA 2O7BA 4CQ5A 2NYFA 2HVGA 4MX2A 1W27A 3QBPA 3TV2A 1C3CA 2QGAB 2X75A 1GK3A 2O7EA 1FUPA 5HW2A 1B8FA 1HY1A 2O78A 1K62A 2OHYA 5EYVA 1Q5NA 1RE5A 4APAA 3KDZA 2PFMA 1GKJA 2O6YA 1GK2A 4HGVA 4EFCA 4BAAA 5D6BA 3GTDA 2PTSA 3R6YA 3KDYA 2RJRA 1VDKA 2O7FA 1GKMA 3OCFA 5F92A 4ADMA 3E04A 4V2RA 4C5UA 3C8TA 2J91A 2YIIA 3NZ4A 1JSWA 4FFXA 1DOFA 2E9FA 1FUQA 3BHGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TJ7 A;  1YIS A;  1TJW A;  4ADL A;  1FUR A;  5F91 A;  4C5S A;  1C3U A;  1K7W A;  1AUW A;  2RJS A;  1Y2M A;  3RRP A;  3NO9 A;  2PTQ A;  1XWO A;  4NSL A;  1KQ7 A;  1YFM A;  3R6V A;  2NYN A;  1YFE A;  1HY0 A;  4C6G A;  4APB A;  1TJV A;  4NLE A;  1EB4 A;  3R6Q A;  3UNV A;  3OCE A;  1U15 A;  1T6P A;  1I0A A;  1FUO A;  3CZO A;  2VD6 A;  1J3U A;  1T6J A;  1DCN A;  4BAB A;  2O7D A;  2PTR A;  2FUS A;  4EEI A;  4FLC A;  1U16 A;  3GZH A;  5EYT A;  4V2Q A;  1TJU A;  2QVE A;  3RD8 A;  4C5R A;  2O7B A;  4CQ5 A;  2NYF A;  2HVG A;  4MX2 A;  1W27 A;  3QBP A;  3TV2 A;  1C3C A;  2QGA B;  2X75 A;  1GK3 A;  2O7E A;  1FUP A;  5HW2 A;  1B8F A;  1HY1 A;  2O78 A;  1K62 A;  2OHY A;  5EYV A;  1Q5N A;  1RE5 A;  4APA A;  3KDZ A;  2PFM A;  1GKJ A;  2O6Y A;  1GK2 A;  4HGV A;  4EFC A;  4BAA A;  5D6B A;  3GTD A;  2PTS A;  3R6Y A;  3KDY A;  2RJR A;  1VDK A;  2O7F A;  1GKM A;  3OCF A;  5F92 A;  4ADM A;  3E04 A;  4V2R A;  4C5U A;  3C8T A;  2J91 A;  2YII A;  3NZ4 A;  1JSW A;  4FFX A;  1DOF A;  2E9F A;  1FUQ A;  3BHG A; 
#chains in the Genus database with same CATH topology
 1TJ7 A;  1Z4J A;  2RCN A;  1TJW A;  2JAU A;  1FUR A;  3BWV A;  4ADL A;  5F91 A;  1YIS A;  4C5S A;  1C3U A;  1K7W A;  1AUW A;  1XL8 A;  2RJS A;  1Y2M A;  3RRP A;  1IW7 D;  4MWO A;  3NO9 A;  2PTQ A;  3F4T A;  4A15 A;  1XWO A;  4NSL A;  1KQ7 A;  1YFM A;  3R6V A;  2NYN A;  1YFE A;  1HY0 A;  4C6G A;  4APB A;  4NFL A;  3CRV A;  4YIK A;  1TJV A;  4NLE A;  1EB4 A;  3R6Q A;  2FEL A;  3UNV A;  3OCE A;  4L6C A;  4L6A A;  4IQJ M;  1U15 A;  4MUM A;  1T6P A;  1I0A A;  1FUO A;  3CZO A;  3CI0 K;  3U13 A;  2VD6 A;  1XLY A;  1J3U A;  1T6J A;  1DCN A;  4BAB A;  2O7D A;  2VL7 A;  2D28 C;  2PTR A;  2I7D A;  2FUS A;  4EEI A;  4FLC A;  1U16 A;  3GZH A;  4YIH A;  2VSF A;  5EYT A;  4V2Q A;  4WNL A;  1TJU A;  2YV5 A;  3RD8 A;  2QVE A;  2O7B A;  4C5R A;  4CQ5 A;  4E88 A;  2NYF A;  2HVG A;  1Z4K A;  4MX2 A;  3U19 A;  1W27 A;  3QBP A;  3TV2 A;  1C3C A;  2QGA B;  2X75 A;  1Z4Q A;  1XMD A;  1Z4I A;  1XL7 A;  3F4R A;  3F4S A;  1GK3 A;  2O7E A;  1FUP A;  5HW2 A;  1Q91 A;  1Q92 A;  2D27 A;  1XMC A;  1B8F A;  5M0J A;  1HY1 A;  2JAO A;  2O78 A;  1K62 A;  2OHY A;  5EYV A;  5H8W A;  1MH9 A;  1Q5N A;  1T9H A;  1RE5 A;  2JAW A;  4APA A;  3KDZ A;  2PFM A;  2JAR A;  1Z4M A;  1GKJ A;  2FEN A;  2O6Y A;  1GK2 A;  4HGV A;  4EFC A;  4BAA A;  5D6B A;  3GTD A;  2PTS A;  3R6Y A;  3KDY A;  2RJR A;  1VDK A;  2O7F A;  1GKM A;  3OCF A;  5F92 A;  3CRW 1;  1U0L A;  4ADM A;  3E04 A;  4V2R A;  4C5U A;  3C8T A;  1Z4P X;  2J91 A;  2YII A;  3NZ4 A;  1JSW A;  4L57 A;  1Z4L A;  4FFX A;  1DOF A;  2E9F A;  5M0I A;  1FUQ A;  3BHG A; 
#chains in the Genus database with same CATH homology
 1TJ7 A;  1YIS A;  1TJW A;  4ADL A;  1FUR A;  5F91 A;  4C5S A;  1C3U A;  1K7W A;  1AUW A;  2RJS A;  1Y2M A;  3RRP A;  3NO9 A;  2PTQ A;  1XWO A;  4NSL A;  1KQ7 A;  1YFM A;  3R6V A;  2NYN A;  1YFE A;  1HY0 A;  4C6G A;  4APB A;  1TJV A;  4NLE A;  1EB4 A;  3R6Q A;  3UNV A;  3OCE A;  1U15 A;  1T6P A;  1I0A A;  1FUO A;  3CZO A;  2VD6 A;  1J3U A;  1T6J A;  1DCN A;  4BAB A;  2O7D A;  2PTR A;  2FUS A;  4EEI A;  4FLC A;  1U16 A;  3GZH A;  5EYT A;  4V2Q A;  1TJU A;  2QVE A;  3RD8 A;  4C5R A;  2O7B A;  4CQ5 A;  2NYF A;  2HVG A;  4MX2 A;  1W27 A;  3QBP A;  3TV2 A;  1C3C A;  2QGA B;  2X75 A;  1GK3 A;  2O7E A;  1FUP A;  5HW2 A;  1B8F A;  1HY1 A;  2O78 A;  1K62 A;  2OHY A;  5EYV A;  1Q5N A;  1RE5 A;  4APA A;  3KDZ A;  2PFM A;  1GKJ A;  2O6Y A;  1GK2 A;  4HGV A;  4EFC A;  4BAA A;  5D6B A;  3GTD A;  2PTS A;  3R6Y A;  3KDY A;  2RJR A;  1VDK A;  2O7F A;  1GKM A;  3OCF A;  5F92 A;  4ADM A;  3E04 A;  4V2R A;  4C5U A;  3C8T A;  2J91 A;  2YII A;  3NZ4 A;  1JSW A;  4FFX A;  1DOF A;  2E9F A;  1FUQ A;  3BHG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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