4HGVA

Crystal structure of a fumarate hydratase
Total Genus 158
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
sequence length
461
structure length
456
Chain Sequence
STRTETDTFGPIEVASDRYWGAQAQRSLGNFKIGWEKQPLAIVRALGIVKQAAARANMALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLGGVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFDHIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAPVGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLGSGPRSGLGELSLPENEPGSKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELNVYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYDNAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Fumarate hydratase class II
publication title Crystal structure of a fumarate hydratase
rcsb
source organism Sinorhizobium meliloti
molecule tags Lyase
total genus 158
structure length 456
sequence length 461
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4hgvA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4hgvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4hgvA02
2O6YA 3UNVA 2O7BA 3NO9A 3KDZA 5D6BA 2E9FA 4ADLA 1FUOA 3CZOA 3OCFA 5HW2A 1B8FA 2PTSA 1K7WA 3TV2A 1XWOA 2X75A 1HY0A 2YIIA 4C6GA 4APAA 3QBPA 3BHGA 1T6JA 4BABA 3R6YA 5EYTA 4FLCA 1C3UA 1I0AA 2RJSA 2VD6A 4FFXA 2O78A 1RE5A 2PFMA 1U15A 1FUPA 4HGVA 5F91A 2O7FA 1GKJA 1YISA 3R6QA 2PTQA 1FUQA 1GK2A 3KDYA 4C5RA 2QGAB 1TJWA 5EYVA 1YFMA 1T6PA 2FUSA 4MX2A 3R6VA 2OHYA 1FURA 4C5UA 4EEIA 5F92A 1W27A 4C5SA 4ADMA 1J3UA 3NZ4A 1TJ7A 2PTRA 1TJVA 4EFCA 2NYFA 4NSLA 1K62A 4BAAA 4NLEA 1AUWA 1Y2MA 1U16A 4CQ5A 4V2RA 3RRPA 3GTDA 1HY1A 1DOFA 1EB4A 2HVGA 1Q5NA 2RJRA 2J91A 4V2QA 1KQ7A 1DCNA 1JSWA 1YFEA 3GZHA 2NYNA 1GKMA 2O7EA 1GK3A 3E04A 1TJUA 2O7DA 1C3CA 4APBA 3OCEA 3C8TA 3RD8A 1VDKA 2QVEA
chains in the Genus database with same CATH superfamily
2O6YA 3UNVA 1XL8A 2O7BA 3NO9A 3KDZA 5D6BA 4L57A 5M0JA 1Q91A 1Z4IA 2E9FA 4ADLA 1FUOA 3CZOA 3OCFA 5HW2A 1B8FA 1T9HA 2D27A 2PTSA 1K7WA 3TV2A 1Q92A 1XWOA 4NFLA 2X75A 5M0IA 3CRW1 1HY0A 2JAOA 5H8WA 1MH9A 2YIIA 4C6GA 4APAA 3QBPA 3BHGA 4YIKA 1T6JA 4BABA 3R6YA 3BWVA 5EYTA 1XLYA 4IQJM 1XL7A 4FLCA 1C3UA 3U13A 1I0AA 4A15A 3CRVA 1U0LA 2FENA 2FELA 2RJSA 2VD6A 1Z4QA 4CQ5A 4FFXA 2O78A 1Z4LA 1RE5A 2D28C 1U15A 1FUPA 2JAWA 2PFMA 4HGVA 5F91A 2O7FA 2YV5A 1GKJA 2JAUA 1YISA 3R6QA 2PTQA 1FUQA 1GK2A 3KDYA 4C5RA 2QGAB 1TJWA 3U19A 2RCNA 5EYVA 1Z4KA 4MUMA 1YFMA 1XMCA 1T6PA 2JARA 1Z4MA 2FUSA 4MX2A 4YIHA 3R6VA 2OHYA 3F4SA 3CI0K 1FURA 4C5UA 4EEIA 5F92A 1W27A 4L6CA 1XMDA 2VL7A 4C5SA 3F4RA 4ADMA 2I7DA 1J3UA 3NZ4A 1TJ7A 2PTRA 1TJVA 4EFCA 2NYFA 4NSLA 1K62A 4BAAA 4L6AA 1AUWA 1U16A 4NLEA 1Y2MA 4V2RA 3RRPA 3GTDA 1HY1A 1DOFA 1Z4PX 1EB4A 2HVGA 1Q5NA 2RJRA 2J91A 4V2QA 1KQ7A 1DCNA 1JSWA 1YFEA 3GZHA 2NYNA 1GKMA 4MWOA 1Z4JA 2O7EA 1GK3A 1IW7D 3E04A 1TJUA 2O7DA 2VSFA 3F4TA 4E88A 4WNLA 1C3CA 4APBA 3OCEA 3C8TA 3RD8A 1VDKA 2QVEA
chains in the Genus database with same CATH topology
2O6YA 3UNVA 2O7BA 3NO9A 3KDZA 5D6BA 2E9FA 4ADLA 1FUOA 3CZOA 3OCFA 5HW2A 1B8FA 2PTSA 1K7WA 3TV2A 1XWOA 2X75A 1HY0A 2YIIA 4C6GA 4APAA 3QBPA 3BHGA 1T6JA 4BABA 3R6YA 5EYTA 4FLCA 1C3UA 1I0AA 2RJSA 2VD6A 4FFXA 2O78A 1RE5A 2PFMA 1U15A 1FUPA 4HGVA 5F91A 2O7FA 1GKJA 1YISA 3R6QA 2PTQA 1FUQA 1GK2A 3KDYA 4C5RA 2QGAB 1TJWA 5EYVA 1YFMA 1T6PA 2FUSA 4MX2A 3R6VA 2OHYA 1FURA 4C5UA 4EEIA 5F92A 1W27A 4C5SA 4ADMA 1J3UA 3NZ4A 1TJ7A 2PTRA 1TJVA 4EFCA 2NYFA 4NSLA 1K62A 4BAAA 4NLEA 1AUWA 1Y2MA 1U16A 4CQ5A 4V2RA 3RRPA 3GTDA 1HY1A 1DOFA 1EB4A 2HVGA 1Q5NA 2RJRA 2J91A 4V2QA 1KQ7A 1DCNA 1JSWA 1YFEA 3GZHA 2NYNA 1GKMA 2O7EA 1GK3A 3E04A 1TJUA 2O7DA 1C3CA 4APBA 3OCEA 3C8TA 3RD8A 1VDKA 2QVEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O6Y A;  3UNV A;  2O7B A;  3NO9 A;  3KDZ A;  5D6B A;  2E9F A;  4ADL A;  1FUO A;  3CZO A;  3OCF A;  5HW2 A;  1B8F A;  2PTS A;  1K7W A;  3TV2 A;  1XWO A;  2X75 A;  1HY0 A;  2YII A;  4C6G A;  4APA A;  3QBP A;  3BHG A;  1T6J A;  4BAB A;  3R6Y A;  5EYT A;  4FLC A;  1C3U A;  1I0A A;  2RJS A;  2VD6 A;  4FFX A;  2O78 A;  1RE5 A;  2PFM A;  1U15 A;  1FUP A;  4HGV A;  5F91 A;  2O7F A;  1GKJ A;  1YIS A;  3R6Q A;  2PTQ A;  1FUQ A;  1GK2 A;  3KDY A;  4C5R A;  2QGA B;  1TJW A;  5EYV A;  1YFM A;  1T6P A;  2FUS A;  4MX2 A;  3R6V A;  2OHY A;  1FUR A;  4C5U A;  4EEI A;  5F92 A;  1W27 A;  4C5S A;  4ADM A;  1J3U A;  3NZ4 A;  1TJ7 A;  2PTR A;  1TJV A;  4EFC A;  2NYF A;  4NSL A;  1K62 A;  4BAA A;  4NLE A;  1AUW A;  1Y2M A;  1U16 A;  4CQ5 A;  4V2R A;  3RRP A;  3GTD A;  1HY1 A;  1DOF A;  1EB4 A;  2HVG A;  1Q5N A;  2RJR A;  2J91 A;  4V2Q A;  1KQ7 A;  1DCN A;  1JSW A;  1YFE A;  3GZH A;  2NYN A;  1GKM A;  2O7E A;  1GK3 A;  3E04 A;  1TJU A;  2O7D A;  1C3C A;  4APB A;  3OCE A;  3C8T A;  3RD8 A;  1VDK A;  2QVE A; 
#chains in the Genus database with same CATH topology
 2O6Y A;  3UNV A;  1XL8 A;  2O7B A;  3NO9 A;  3KDZ A;  5D6B A;  4L57 A;  5M0J A;  1Q91 A;  1Z4I A;  2E9F A;  4ADL A;  1FUO A;  3CZO A;  3OCF A;  5HW2 A;  1B8F A;  1T9H A;  2D27 A;  2PTS A;  1K7W A;  3TV2 A;  1Q92 A;  1XWO A;  4NFL A;  2X75 A;  5M0I A;  3CRW 1;  1HY0 A;  2JAO A;  5H8W A;  1MH9 A;  2YII A;  4C6G A;  4APA A;  3QBP A;  3BHG A;  4YIK A;  1T6J A;  4BAB A;  3R6Y A;  3BWV A;  5EYT A;  1XLY A;  4IQJ M;  1XL7 A;  4FLC A;  1C3U A;  3U13 A;  1I0A A;  4A15 A;  3CRV A;  1U0L A;  2FEN A;  2FEL A;  2RJS A;  2VD6 A;  1Z4Q A;  4CQ5 A;  4FFX A;  2O78 A;  1Z4L A;  1RE5 A;  2D28 C;  1U15 A;  1FUP A;  2JAW A;  2PFM A;  4HGV A;  5F91 A;  2O7F A;  2YV5 A;  1GKJ A;  2JAU A;  1YIS A;  3R6Q A;  2PTQ A;  1FUQ A;  1GK2 A;  3KDY A;  4C5R A;  2QGA B;  1TJW A;  3U19 A;  2RCN A;  5EYV A;  1Z4K A;  4MUM A;  1YFM A;  1XMC A;  1T6P A;  2JAR A;  1Z4M A;  2FUS A;  4MX2 A;  4YIH A;  3R6V A;  2OHY A;  3F4S A;  3CI0 K;  1FUR A;  4C5U A;  4EEI A;  5F92 A;  1W27 A;  4L6C A;  1XMD A;  2VL7 A;  4C5S A;  3F4R A;  4ADM A;  2I7D A;  1J3U A;  3NZ4 A;  1TJ7 A;  2PTR A;  1TJV A;  4EFC A;  2NYF A;  4NSL A;  1K62 A;  4BAA A;  4L6A A;  1AUW A;  1U16 A;  4NLE A;  1Y2M A;  4V2R A;  3RRP A;  3GTD A;  1HY1 A;  1DOF A;  1Z4P X;  1EB4 A;  2HVG A;  1Q5N A;  2RJR A;  2J91 A;  4V2Q A;  1KQ7 A;  1DCN A;  1JSW A;  1YFE A;  3GZH A;  2NYN A;  1GKM A;  4MWO A;  1Z4J A;  2O7E A;  1GK3 A;  1IW7 D;  3E04 A;  1TJU A;  2O7D A;  2VSF A;  3F4T A;  4E88 A;  4WNL A;  1C3C A;  4APB A;  3OCE A;  3C8T A;  3RD8 A;  1VDK A;  2QVE A; 
#chains in the Genus database with same CATH homology
 2O6Y A;  3UNV A;  2O7B A;  3NO9 A;  3KDZ A;  5D6B A;  2E9F A;  4ADL A;  1FUO A;  3CZO A;  3OCF A;  5HW2 A;  1B8F A;  2PTS A;  1K7W A;  3TV2 A;  1XWO A;  2X75 A;  1HY0 A;  2YII A;  4C6G A;  4APA A;  3QBP A;  3BHG A;  1T6J A;  4BAB A;  3R6Y A;  5EYT A;  4FLC A;  1C3U A;  1I0A A;  2RJS A;  2VD6 A;  4FFX A;  2O78 A;  1RE5 A;  2PFM A;  1U15 A;  1FUP A;  4HGV A;  5F91 A;  2O7F A;  1GKJ A;  1YIS A;  3R6Q A;  2PTQ A;  1FUQ A;  1GK2 A;  3KDY A;  4C5R A;  2QGA B;  1TJW A;  5EYV A;  1YFM A;  1T6P A;  2FUS A;  4MX2 A;  3R6V A;  2OHY A;  1FUR A;  4C5U A;  4EEI A;  5F92 A;  1W27 A;  4C5S A;  4ADM A;  1J3U A;  3NZ4 A;  1TJ7 A;  2PTR A;  1TJV A;  4EFC A;  2NYF A;  4NSL A;  1K62 A;  4BAA A;  4NLE A;  1AUW A;  1Y2M A;  1U16 A;  4CQ5 A;  4V2R A;  3RRP A;  3GTD A;  1HY1 A;  1DOF A;  1EB4 A;  2HVG A;  1Q5N A;  2RJR A;  2J91 A;  4V2Q A;  1KQ7 A;  1DCN A;  1JSW A;  1YFE A;  3GZH A;  2NYN A;  1GKM A;  2O7E A;  1GK3 A;  3E04 A;  1TJU A;  2O7D A;  1C3C A;  4APB A;  3OCE A;  3C8T A;  3RD8 A;  1VDK A;  2QVE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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