1C1ZA

Crystal structure of human beta-2-glycoprotein-i (apolipoprotein-h)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
326
structure length
326
Chain Sequence
GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
publication title Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome.
pubmed doi rcsb
molecule keywords BETA2-GLYCOPROTEIN-I
total genus 56
structure length 326
sequence length 326
ec nomenclature
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
A PF09014 Sushi_2 Beta-2-glycoprotein-1 fifth domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA05
3IU3I 1LY2A 2W81A 4CSYA 2JRAA 2RKZA 1MD8A 2CG6A 1C1ZA 4K12A 1GPZA 1H2QP 1QUBA 2RLQA 1OK1A 1G4GA 1SRZA 1OK2A 1E88A 1TPGA 3RJ3D 3R62A 1UOTP 2JGXA 4YNXA 4ONTD 1NWVA 1QGBA 4AYMA 1OK3A 2IZ4A 2XQWC 3ZD1A 4IGDA 2CKUA 1H03P 1SS2A 2RKYA 3KZJA 1GHQB 2IZ3A 3M7PA 5FO8C 3EJHA 4F4OC 2UWNA 2BZMA 1QO6A 2JGWA 3SW0X 3ZD2A 3MQLA 2CG7A 3OEDC 4LOSA 5HZPB 2KRIA 1OJWA 3O8EB 1OJYA 3GOVA 1OJVA 1ELVA 1TPNA 1O9AA 4A5WB 3T5OA 2EC3A 4KKDA 2XWJI 1GKNA 2A55A 5I0QB 2ERJA 1HCCA 2EHFA 1H2PP 3L89M 2RL0A 3OXUD 1CKLA 1HFHA 1E8BA 2MCZA 5JPMG 3INBC 5HYUB 4WJG2 1VVCA 2WIIC 1GKGA 3ERBA 1HFIA 2O39C 1OK9A 3IX0A 2LOJA 3ZRZA 2QY0A 1FBRA 4DJZA 2KMSA 4PZ5A 2B5ID 3CALA 2G7IA 4ZH1D 1PPQA 4AYEA 3OP8A 4B2RA 2YBYA 1MD7A 4B2SA 2RLPA 5HYTB 4C16A 3TVJA 4AYIA 2V8EA 4J38B 4MUCA 1H04P 5HYPA 3GXEA 2MCYA 3NFPI 1Z92B 2XWBF 2W80A 4LOTA 1TPMA 3KXVA 1Q3XA 2YRAA 1ZJKA 1G4FA 4JHSA 4AYDA 1VVDA 2XRDA 1U5MA 1E5GA 4FXGG 2XRBA
chains in the Genus database with same CATH superfamily
3IU3I 1LY2A 2W81A 4CSYA 5DN5A 2JRAA 2RKZA 1MD8A 2CG6A 1C1ZA 4K12A 1GPZA 1H2QP 3CI0J 2X2ZA 1QUBA 2RLQA 1OK1A 1G4GA 1SRZA 1OK2A 1E88A 1TPGA 3K3TA 3R62A 1UOTP 3RJ3D 4MSLA 2JGXA 4YNXA 4ONTD 1NWVA 1QGBA 4AYMA 1OK3A 3FGTA 2IZ4A 2XQWC 3ZD1A 4IGDA 2CKUA 1H03P 2Y8SA 3FGRA 1SS2A 2I2LA 2RKYA 3KZJA 1GHQB 2IZ3A 3M7PA 2Y8TA 5FO8C 3EJHA 4F4OC 2UWNA 2BZMA 1QO6A 2JGWA 3SW0X 3ZD2A 3MQLA 2CG7A 3OEDC 4LOSA 5HZPB 2KRIA 3VWOA 1OJWA 3O8EB 1OJYA 3GOVA 1OJVA 1ELVA 1TPNA 1O9AA 3NJAA 4A5WB 3T5OA 2EC3A 4KKDA 2XWJI 1GKNA 2A55A 5I0QB 2Y8RA 2ERJA 1HCCA 2EHFA 1H2PP 3L89M 3WSYA 1RLHA 2RL0A 3OXUD 3ZLEA 1CKLA 1HFHA 1E8BA 2MCZA 5DN4A 5JPMG 3INBC 5HYUB 4WJG2 1VVCA 2WIIC 1GKGA 4N7EA 3ERBA 1HFIA 2O39C 1OK9A 3IX0A 2LOJA 3ZRZA 2QY0A 1FBRA 4DJZA 2KMSA 4PZ5A 2B5ID 3CALA 2G7IA 4ZH1D 1PPQA 4AYEA 3OP8A 4B2RA 2YBYA 1MD7A 3WSXA 4B2SA 2RLPA 4YIZA 5HYTB 4C16A 4APLA 3ZLDA 4BWCA 3TVJA 4AYIA 2V8EA 4J38B 4MUCA 1H04P 5HYPA 3GXEA 2MCYA 3NFPI 1Z92B 2XWBF 2ZYCA 2W80A 4LOTA 1TPMA 3KXVA 4PO7A 1Q3XA 2YRAA 1ZJKA 1G4FA 4JHSA 4AYDA 1VVDA 2XRDA 1U5MA 1E5GA 4FXGG 2XRBA 3F6KA
chains in the Genus database with same CATH topology
3IU3I 1LY2A 2W81A 4CSYA 2JRAA 2RKZA 1MD8A 2CG6A 1C1ZA 4K12A 1GPZA 1H2QP 1QUBA 2RLQA 1OK1A 1G4GA 1SRZA 1OK2A 1E88A 1TPGA 3RJ3D 3R62A 1UOTP 2JGXA 4YNXA 4ONTD 1NWVA 1QGBA 4AYMA 1OK3A 2IZ4A 2XQWC 3ZD1A 4IGDA 2CKUA 1H03P 1SS2A 2RKYA 3KZJA 1GHQB 2IZ3A 3M7PA 5FO8C 3EJHA 4F4OC 2UWNA 2BZMA 1QO6A 2JGWA 3SW0X 3ZD2A 3MQLA 2CG7A 3OEDC 4LOSA 5HZPB 2KRIA 1OJWA 3O8EB 1OJYA 3GOVA 1OJVA 1ELVA 1TPNA 1O9AA 4A5WB 3T5OA 2EC3A 4KKDA 2XWJI 1GKNA 2A55A 5I0QB 2ERJA 1HCCA 2EHFA 1H2PP 3L89M 2RL0A 3OXUD 1CKLA 1HFHA 1E8BA 2MCZA 5JPMG 3INBC 5HYUB 4WJG2 1VVCA 2WIIC 1GKGA 3ERBA 1HFIA 2O39C 1OK9A 3IX0A 2LOJA 3ZRZA 2QY0A 1FBRA 4DJZA 2KMSA 4PZ5A 2B5ID 3CALA 2G7IA 4ZH1D 1PPQA 4AYEA 3OP8A 4B2RA 2YBYA 1MD7A 4B2SA 2RLPA 5HYTB 4C16A 3TVJA 4AYIA 2V8EA 4J38B 4MUCA 1H04P 5HYPA 3GXEA 2MCYA 3NFPI 1Z92B 2XWBF 2W80A 4LOTA 1TPMA 3KXVA 1Q3XA 2YRAA 1ZJKA 1G4FA 4JHSA 4AYDA 1VVDA 2XRDA 1U5MA 1E5GA 4FXGG 2XRBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IU3 I;  1LY2 A;  2W81 A;  4CSY A;  2JRA A;  2RKZ A;  1MD8 A;  2CG6 A;  1C1Z A;  4K12 A;  1GPZ A;  1H2Q P;  1QUB A;  2RLQ A;  1OK1 A;  1G4G A;  1SRZ A;  1OK2 A;  1E88 A;  1TPG A;  3RJ3 D;  3R62 A;  1UOT P;  2JGX A;  4YNX A;  4ONT D;  1NWV A;  1QGB A;  4AYM A;  1OK3 A;  2IZ4 A;  2XQW C;  3ZD1 A;  4IGD A;  2CKU A;  1H03 P;  1SS2 A;  2RKY A;  3KZJ A;  1GHQ B;  2IZ3 A;  3M7P A;  5FO8 C;  3EJH A;  4F4O C;  2UWN A;  2BZM A;  1QO6 A;  2JGW A;  3SW0 X;  3ZD2 A;  3MQL A;  2CG7 A;  3OED C;  4LOS A;  5HZP B;  2KRI A;  1OJW A;  3O8E B;  1OJY A;  3GOV A;  1OJV A;  1ELV A;  1TPN A;  1O9A A;  4A5W B;  3T5O A;  2EC3 A;  4KKD A;  2XWJ I;  1GKN A;  2A55 A;  5I0Q B;  2ERJ A;  1HCC A;  2EHF A;  1H2P P;  3L89 M;  2RL0 A;  3OXU D;  1CKL A;  1HFH A;  1E8B A;  2MCZ A;  5JPM G;  3INB C;  5HYU B;  4WJG 2;  1VVC A;  2WII C;  1GKG A;  3ERB A;  1HFI A;  2O39 C;  1OK9 A;  3IX0 A;  2LOJ A;  3ZRZ A;  2QY0 A;  1FBR A;  4DJZ A;  2KMS A;  4PZ5 A;  2B5I D;  3CAL A;  2G7I A;  4ZH1 D;  1PPQ A;  4AYE A;  3OP8 A;  4B2R A;  2YBY A;  1MD7 A;  4B2S A;  2RLP A;  5HYT B;  4C16 A;  3TVJ A;  4AYI A;  2V8E A;  4J38 B;  4MUC A;  1H04 P;  5HYP A;  3GXE A;  2MCY A;  3NFP I;  1Z92 B;  2XWB F;  2W80 A;  4LOT A;  1TPM A;  3KXV A;  1Q3X A;  2YRA A;  1ZJK A;  1G4F A;  4JHS A;  4AYD A;  1VVD A;  2XRD A;  1U5M A;  1E5G A;  4FXG G;  2XRB A; 
#chains in the Genus database with same CATH topology
 3IU3 I;  1LY2 A;  2W81 A;  4CSY A;  5DN5 A;  2JRA A;  2RKZ A;  1MD8 A;  2CG6 A;  1C1Z A;  4K12 A;  1GPZ A;  1H2Q P;  3CI0 J;  2X2Z A;  1QUB A;  2RLQ A;  1OK1 A;  1G4G A;  1SRZ A;  1OK2 A;  1E88 A;  1TPG A;  3K3T A;  3R62 A;  1UOT P;  3RJ3 D;  4MSL A;  2JGX A;  4YNX A;  4ONT D;  1NWV A;  1QGB A;  4AYM A;  1OK3 A;  3FGT A;  2IZ4 A;  2XQW C;  3ZD1 A;  4IGD A;  2CKU A;  1H03 P;  2Y8S A;  3FGR A;  1SS2 A;  2I2L A;  2RKY A;  3KZJ A;  1GHQ B;  2IZ3 A;  3M7P A;  2Y8T A;  5FO8 C;  3EJH A;  4F4O C;  2UWN A;  2BZM A;  1QO6 A;  2JGW A;  3SW0 X;  3ZD2 A;  3MQL A;  2CG7 A;  3OED C;  4LOS A;  5HZP B;  2KRI A;  3VWO A;  1OJW A;  3O8E B;  1OJY A;  3GOV A;  1OJV A;  1ELV A;  1TPN A;  1O9A A;  3NJA A;  4A5W B;  3T5O A;  2EC3 A;  4KKD A;  2XWJ I;  1GKN A;  2A55 A;  5I0Q B;  2Y8R A;  2ERJ A;  1HCC A;  2EHF A;  1H2P P;  3L89 M;  3WSY A;  1RLH A;  2RL0 A;  3OXU D;  3ZLE A;  1CKL A;  1HFH A;  1E8B A;  2MCZ A;  5DN4 A;  5JPM G;  3INB C;  5HYU B;  4WJG 2;  1VVC A;  2WII C;  1GKG A;  4N7E A;  3ERB A;  1HFI A;  2O39 C;  1OK9 A;  3IX0 A;  2LOJ A;  3ZRZ A;  2QY0 A;  1FBR A;  4DJZ A;  2KMS A;  4PZ5 A;  2B5I D;  3CAL A;  2G7I A;  4ZH1 D;  1PPQ A;  4AYE A;  3OP8 A;  4B2R A;  2YBY A;  1MD7 A;  3WSX A;  4B2S A;  2RLP A;  4YIZ A;  5HYT B;  4C16 A;  4APL A;  3ZLD A;  4BWC A;  3TVJ A;  4AYI A;  2V8E A;  4J38 B;  4MUC A;  1H04 P;  5HYP A;  3GXE A;  2MCY A;  3NFP I;  1Z92 B;  2XWB F;  2ZYC A;  2W80 A;  4LOT A;  1TPM A;  3KXV A;  4PO7 A;  1Q3X A;  2YRA A;  1ZJK A;  1G4F A;  4JHS A;  4AYD A;  1VVD A;  2XRD A;  1U5M A;  1E5G A;  4FXG G;  2XRB A;  3F6K A; 
#chains in the Genus database with same CATH homology
 3IU3 I;  1LY2 A;  2W81 A;  4CSY A;  2JRA A;  2RKZ A;  1MD8 A;  2CG6 A;  1C1Z A;  4K12 A;  1GPZ A;  1H2Q P;  1QUB A;  2RLQ A;  1OK1 A;  1G4G A;  1SRZ A;  1OK2 A;  1E88 A;  1TPG A;  3RJ3 D;  3R62 A;  1UOT P;  2JGX A;  4YNX A;  4ONT D;  1NWV A;  1QGB A;  4AYM A;  1OK3 A;  2IZ4 A;  2XQW C;  3ZD1 A;  4IGD A;  2CKU A;  1H03 P;  1SS2 A;  2RKY A;  3KZJ A;  1GHQ B;  2IZ3 A;  3M7P A;  5FO8 C;  3EJH A;  4F4O C;  2UWN A;  2BZM A;  1QO6 A;  2JGW A;  3SW0 X;  3ZD2 A;  3MQL A;  2CG7 A;  3OED C;  4LOS A;  5HZP B;  2KRI A;  1OJW A;  3O8E B;  1OJY A;  3GOV A;  1OJV A;  1ELV A;  1TPN A;  1O9A A;  4A5W B;  3T5O A;  2EC3 A;  4KKD A;  2XWJ I;  1GKN A;  2A55 A;  5I0Q B;  2ERJ A;  1HCC A;  2EHF A;  1H2P P;  3L89 M;  2RL0 A;  3OXU D;  1CKL A;  1HFH A;  1E8B A;  2MCZ A;  5JPM G;  3INB C;  5HYU B;  4WJG 2;  1VVC A;  2WII C;  1GKG A;  3ERB A;  1HFI A;  2O39 C;  1OK9 A;  3IX0 A;  2LOJ A;  3ZRZ A;  2QY0 A;  1FBR A;  4DJZ A;  2KMS A;  4PZ5 A;  2B5I D;  3CAL A;  2G7I A;  4ZH1 D;  1PPQ A;  4AYE A;  3OP8 A;  4B2R A;  2YBY A;  1MD7 A;  4B2S A;  2RLP A;  5HYT B;  4C16 A;  3TVJ A;  4AYI A;  2V8E A;  4J38 B;  4MUC A;  1H04 P;  5HYP A;  3GXE A;  2MCY A;  3NFP I;  1Z92 B;  2XWB F;  2W80 A;  4LOT A;  1TPM A;  3KXV A;  1Q3X A;  2YRA A;  1ZJK A;  1G4F A;  4JHS A;  4AYD A;  1VVD A;  2XRD A;  1U5M A;  1E5G A;  4FXG G;  2XRB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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