1C1ZA

Crystal structure of human beta-2-glycoprotein-i (apolipoprotein-h)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
326
structure length
326
Chain Sequence
GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome.
pubmed doi rcsb
molecule tags Signaling protein
molecule keywords BETA2-GLYCOPROTEIN-I
total genus 56
structure length 326
sequence length 326
ec nomenclature
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
A PF09014 Sushi_2 Beta-2-glycoprotein-1 fifth domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA05
4IGDA 1OJWA 1VVDA 3OP8A 1G4FA 1MD7A 1HFIA 1OK3A 2XWBF 2YBYA 4AYDA 1MD8A 2O39C 1H04P 3GOVA 4WJG2 2XRBA 3MQLA 1Q3XA 3CALA 1O9AA 4B2RA 3NFPI 1GHQB 3TVJA 1NWVA 2LOJA 1TPGA 4KKDA 1H03P 2UWNA 3KZJA 2RKZA 2CKUA 3KXVA 1VVCA 2MCZA 4LOTA 3ZD1A 2IZ3A 5HYPA 3ERBA 4DJZA 5HYUB 3R62A 1CKLA 1PPQA 3L89M 3M7PA 3OXUD 4FXGG 2WIIC 1G4GA 1H2PP 4PZ5A 4B2SA 1LY2A 2QY0A 4LOSA 4A5WB 4AYMA 1ZJKA 1OJVA 1E5GA 1QO6A 1QUBA 1Z92B 3RJ3D 1GKGA 3OEDC 1HFHA 1OJYA 1SRZA 5I0QB 1SS2A 4C16A 5JPMG 2YRAA 5HZPB 2XQWC 2BZMA 1E8BA 1GPZA 4ONTD 2KRIA 2CG7A 2EHFA 4JHSA 5FO8C 1UOTP 1E88A 3IX0A 4YNXA 2JGWA 3EJHA 2ERJA 3ZRZA 2IZ4A 2A55A 3IU3I 4K12A 2W81A 1OK1A 2RLPA 4AYIA 4F4OC 1TPNA 5HYTB 1U5MA 3ZD2A 4ZH1D 2XRDA 2JRAA 1OK2A 2V8EA 2W80A 2G7IA 4MUCA 1FBRA 2RLQA 2XWJI 2RL0A 2EC3A 2B5ID 1GKNA 1H2QP 2KMSA 3O8EB 2CG6A 3INBC 1TPMA 4AYEA 1C1ZA 1OK9A 4CSYA 3GXEA 1HCCA 2MCYA 4J38B 3T5OA 2RKYA 3SW0X 1ELVA 2JGXA 1QGBA
chains in the Genus database with same CATH superfamily
4IGDA 1OJWA 1VVDA 3OP8A 3WSXA 1G4FA 1MD7A 1HFIA 1OK3A 2XWBF 2Y8TA 2YBYA 5DN4A 4AYDA 1MD8A 2O39C 1H04P 3GOVA 4WJG2 2XRBA 3MQLA 1Q3XA 3CALA 1O9AA 4B2RA 4PO7A 3NFPI 1GHQB 3TVJA 2ZYCA 1RLHA 1NWVA 2LOJA 1TPGA 4KKDA 1H03P 2UWNA 3KZJA 2RKZA 2CKUA 3KXVA 1VVCA 2MCZA 4LOTA 3WSYA 3K3TA 3ZD1A 3ZLEA 2IZ3A 5HYPA 3ERBA 4APLA 4DJZA 5HYUB 3R62A 1CKLA 1PPQA 3L89M 3M7PA 3OXUD 4FXGG 2WIIC 1G4GA 1H2PP 4PZ5A 4YIZA 4B2SA 1LY2A 3F6KA 2QY0A 4LOSA 4A5WB 4AYMA 1ZJKA 1OJVA 1E5GA 4N7EA 1QO6A 1QUBA 1Z92B 3VWOA 3RJ3D 1GKGA 3OEDC 5DN5A 1HFHA 1OJYA 1SRZA 5I0QB 1SS2A 4C16A 5JPMG 2YRAA 5HZPB 2XQWC 2BZMA 1E8BA 2Y8SA 1GPZA 4ONTD 2KRIA 2CG7A 2EHFA 4JHSA 5FO8C 3FGRA 1UOTP 1E88A 3IX0A 3NJAA 4YNXA 2JGWA 3EJHA 2ERJA 3ZRZA 2IZ4A 2A55A 3IU3I 4K12A 2W81A 1OK1A 2RLPA 4AYIA 4F4OC 3FGTA 1TPNA 5HYTB 1U5MA 3ZD2A 4ZH1D 2I2LA 2XRDA 2JRAA 2Y8RA 1OK2A 2V8EA 4MSLA 2W80A 4BWCA 2G7IA 4MUCA 1FBRA 3CI0J 2RLQA 2XWJI 2RL0A 2EC3A 2B5ID 1GKNA 1H2QP 2KMSA 3O8EB 2CG6A 3INBC 1TPMA 4AYEA 3ZLDA 1C1ZA 1OK9A 4CSYA 3GXEA 1HCCA 2MCYA 4J38B 3T5OA 2RKYA 2X2ZA 3SW0X 1ELVA 2JGXA 1QGBA
chains in the Genus database with same CATH topology
4IGDA 1OJWA 1VVDA 3OP8A 1G4FA 1MD7A 1HFIA 1OK3A 2XWBF 2YBYA 4AYDA 1MD8A 2O39C 1H04P 3GOVA 4WJG2 2XRBA 3MQLA 1Q3XA 3CALA 1O9AA 4B2RA 3NFPI 1GHQB 3TVJA 1NWVA 2LOJA 1TPGA 4KKDA 1H03P 2UWNA 3KZJA 2RKZA 2CKUA 3KXVA 1VVCA 2MCZA 4LOTA 3ZD1A 2IZ3A 5HYPA 3ERBA 4DJZA 5HYUB 3R62A 1CKLA 1PPQA 3L89M 3M7PA 3OXUD 4FXGG 2WIIC 1G4GA 1H2PP 4PZ5A 4B2SA 1LY2A 2QY0A 4LOSA 4A5WB 4AYMA 1ZJKA 1OJVA 1E5GA 1QO6A 1QUBA 1Z92B 3RJ3D 1GKGA 3OEDC 1HFHA 1OJYA 1SRZA 5I0QB 1SS2A 4C16A 5JPMG 2YRAA 5HZPB 2XQWC 2BZMA 1E8BA 1GPZA 4ONTD 2KRIA 2CG7A 2EHFA 4JHSA 5FO8C 1UOTP 1E88A 3IX0A 4YNXA 2JGWA 3EJHA 2ERJA 3ZRZA 2IZ4A 2A55A 3IU3I 4K12A 2W81A 1OK1A 2RLPA 4AYIA 4F4OC 1TPNA 5HYTB 1U5MA 3ZD2A 4ZH1D 2XRDA 2JRAA 1OK2A 2V8EA 2W80A 2G7IA 4MUCA 1FBRA 2RLQA 2XWJI 2RL0A 2EC3A 2B5ID 1GKNA 1H2QP 2KMSA 3O8EB 2CG6A 3INBC 1TPMA 4AYEA 1C1ZA 1OK9A 4CSYA 3GXEA 1HCCA 2MCYA 4J38B 3T5OA 2RKYA 3SW0X 1ELVA 2JGXA 1QGBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IGD A;  1OJW A;  1VVD A;  3OP8 A;  1G4F A;  1MD7 A;  1HFI A;  1OK3 A;  2XWB F;  2YBY A;  4AYD A;  1MD8 A;  2O39 C;  1H04 P;  3GOV A;  4WJG 2;  2XRB A;  3MQL A;  1Q3X A;  3CAL A;  1O9A A;  4B2R A;  3NFP I;  1GHQ B;  3TVJ A;  1NWV A;  2LOJ A;  1TPG A;  4KKD A;  1H03 P;  2UWN A;  3KZJ A;  2RKZ A;  2CKU A;  3KXV A;  1VVC A;  2MCZ A;  4LOT A;  3ZD1 A;  2IZ3 A;  5HYP A;  3ERB A;  4DJZ A;  5HYU B;  3R62 A;  1CKL A;  1PPQ A;  3L89 M;  3M7P A;  3OXU D;  4FXG G;  2WII C;  1G4G A;  1H2P P;  4PZ5 A;  4B2S A;  1LY2 A;  2QY0 A;  4LOS A;  4A5W B;  4AYM A;  1ZJK A;  1OJV A;  1E5G A;  1QO6 A;  1QUB A;  1Z92 B;  3RJ3 D;  1GKG A;  3OED C;  1HFH A;  1OJY A;  1SRZ A;  5I0Q B;  1SS2 A;  4C16 A;  5JPM G;  2YRA A;  5HZP B;  2XQW C;  2BZM A;  1E8B A;  1GPZ A;  4ONT D;  2KRI A;  2CG7 A;  2EHF A;  4JHS A;  5FO8 C;  1UOT P;  1E88 A;  3IX0 A;  4YNX A;  2JGW A;  3EJH A;  2ERJ A;  3ZRZ A;  2IZ4 A;  2A55 A;  3IU3 I;  4K12 A;  2W81 A;  1OK1 A;  2RLP A;  4AYI A;  4F4O C;  1TPN A;  5HYT B;  1U5M A;  3ZD2 A;  4ZH1 D;  2XRD A;  2JRA A;  1OK2 A;  2V8E A;  2W80 A;  2G7I A;  4MUC A;  1FBR A;  2RLQ A;  2XWJ I;  2RL0 A;  2EC3 A;  2B5I D;  1GKN A;  1H2Q P;  2KMS A;  3O8E B;  2CG6 A;  3INB C;  1TPM A;  4AYE A;  1C1Z A;  1OK9 A;  4CSY A;  3GXE A;  1HCC A;  2MCY A;  4J38 B;  3T5O A;  2RKY A;  3SW0 X;  1ELV A;  2JGX A;  1QGB A; 
#chains in the Genus database with same CATH topology
 4IGD A;  1OJW A;  1VVD A;  3OP8 A;  3WSX A;  1G4F A;  1MD7 A;  1HFI A;  1OK3 A;  2XWB F;  2Y8T A;  2YBY A;  5DN4 A;  4AYD A;  1MD8 A;  2O39 C;  1H04 P;  3GOV A;  4WJG 2;  2XRB A;  3MQL A;  1Q3X A;  3CAL A;  1O9A A;  4B2R A;  4PO7 A;  3NFP I;  1GHQ B;  3TVJ A;  2ZYC A;  1RLH A;  1NWV A;  2LOJ A;  1TPG A;  4KKD A;  1H03 P;  2UWN A;  3KZJ A;  2RKZ A;  2CKU A;  3KXV A;  1VVC A;  2MCZ A;  4LOT A;  3WSY A;  3K3T A;  3ZD1 A;  3ZLE A;  2IZ3 A;  5HYP A;  3ERB A;  4APL A;  4DJZ A;  5HYU B;  3R62 A;  1CKL A;  1PPQ A;  3L89 M;  3M7P A;  3OXU D;  4FXG G;  2WII C;  1G4G A;  1H2P P;  4PZ5 A;  4YIZ A;  4B2S A;  1LY2 A;  3F6K A;  2QY0 A;  4LOS A;  4A5W B;  4AYM A;  1ZJK A;  1OJV A;  1E5G A;  4N7E A;  1QO6 A;  1QUB A;  1Z92 B;  3VWO A;  3RJ3 D;  1GKG A;  3OED C;  5DN5 A;  1HFH A;  1OJY A;  1SRZ A;  5I0Q B;  1SS2 A;  4C16 A;  5JPM G;  2YRA A;  5HZP B;  2XQW C;  2BZM A;  1E8B A;  2Y8S A;  1GPZ A;  4ONT D;  2KRI A;  2CG7 A;  2EHF A;  4JHS A;  5FO8 C;  3FGR A;  1UOT P;  1E88 A;  3IX0 A;  3NJA A;  4YNX A;  2JGW A;  3EJH A;  2ERJ A;  3ZRZ A;  2IZ4 A;  2A55 A;  3IU3 I;  4K12 A;  2W81 A;  1OK1 A;  2RLP A;  4AYI A;  4F4O C;  3FGT A;  1TPN A;  5HYT B;  1U5M A;  3ZD2 A;  4ZH1 D;  2I2L A;  2XRD A;  2JRA A;  2Y8R A;  1OK2 A;  2V8E A;  4MSL A;  2W80 A;  4BWC A;  2G7I A;  4MUC A;  1FBR A;  3CI0 J;  2RLQ A;  2XWJ I;  2RL0 A;  2EC3 A;  2B5I D;  1GKN A;  1H2Q P;  2KMS A;  3O8E B;  2CG6 A;  3INB C;  1TPM A;  4AYE A;  3ZLD A;  1C1Z A;  1OK9 A;  4CSY A;  3GXE A;  1HCC A;  2MCY A;  4J38 B;  3T5O A;  2RKY A;  2X2Z A;  3SW0 X;  1ELV A;  2JGX A;  1QGB A; 
#chains in the Genus database with same CATH homology
 4IGD A;  1OJW A;  1VVD A;  3OP8 A;  1G4F A;  1MD7 A;  1HFI A;  1OK3 A;  2XWB F;  2YBY A;  4AYD A;  1MD8 A;  2O39 C;  1H04 P;  3GOV A;  4WJG 2;  2XRB A;  3MQL A;  1Q3X A;  3CAL A;  1O9A A;  4B2R A;  3NFP I;  1GHQ B;  3TVJ A;  1NWV A;  2LOJ A;  1TPG A;  4KKD A;  1H03 P;  2UWN A;  3KZJ A;  2RKZ A;  2CKU A;  3KXV A;  1VVC A;  2MCZ A;  4LOT A;  3ZD1 A;  2IZ3 A;  5HYP A;  3ERB A;  4DJZ A;  5HYU B;  3R62 A;  1CKL A;  1PPQ A;  3L89 M;  3M7P A;  3OXU D;  4FXG G;  2WII C;  1G4G A;  1H2P P;  4PZ5 A;  4B2S A;  1LY2 A;  2QY0 A;  4LOS A;  4A5W B;  4AYM A;  1ZJK A;  1OJV A;  1E5G A;  1QO6 A;  1QUB A;  1Z92 B;  3RJ3 D;  1GKG A;  3OED C;  1HFH A;  1OJY A;  1SRZ A;  5I0Q B;  1SS2 A;  4C16 A;  5JPM G;  2YRA A;  5HZP B;  2XQW C;  2BZM A;  1E8B A;  1GPZ A;  4ONT D;  2KRI A;  2CG7 A;  2EHF A;  4JHS A;  5FO8 C;  1UOT P;  1E88 A;  3IX0 A;  4YNX A;  2JGW A;  3EJH A;  2ERJ A;  3ZRZ A;  2IZ4 A;  2A55 A;  3IU3 I;  4K12 A;  2W81 A;  1OK1 A;  2RLP A;  4AYI A;  4F4O C;  1TPN A;  5HYT B;  1U5M A;  3ZD2 A;  4ZH1 D;  2XRD A;  2JRA A;  1OK2 A;  2V8E A;  2W80 A;  2G7I A;  4MUC A;  1FBR A;  2RLQ A;  2XWJ I;  2RL0 A;  2EC3 A;  2B5I D;  1GKN A;  1H2Q P;  2KMS A;  3O8E B;  2CG6 A;  3INB C;  1TPM A;  4AYE A;  1C1Z A;  1OK9 A;  4CSY A;  3GXE A;  1HCC A;  2MCY A;  4J38 B;  3T5O A;  2RKY A;  3SW0 X;  1ELV A;  2JGX A;  1QGB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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