1C1ZA

Crystal structure of human beta-2-glycoprotein-i (apolipoprotein-h)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
326
structure length
326
Chain Sequence
GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome.
pubmed doi rcsb
molecule tags Signaling protein
molecule keywords BETA2-GLYCOPROTEIN-I
total genus 56
structure length 326
sequence length 326
ec nomenclature
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
A PF09014 Sushi_2 Beta-2-glycoprotein-1 fifth domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1c1zA05
2ERJA 4A5WB 4AYEA 1OJWA 2G7IA 5I0QB 1SS2A 4B2SA 4CSYA 4K12A 3MQLA 2IZ3A 1H03P 1NWVA 4C16A 1MD7A 3IX0A 2WIIC 1VVCA 3GOVA 3ZD1A 2KMSA 4LOTA 2UWNA 1OK2A 1HCCA 4AYDA 5JPMG 1SRZA 2A55A 1VVDA 1PPQA 2CKUA 3ERBA 1QO6A 2RKZA 3GXEA 1ZJKA 2JGXA 2MCZA 1TPNA 1UOTP 2RKYA 4ZH1D 1H2PP 2EC3A 3O8EB 2XWJI 2O39C 3L89M 4KKDA 1H2QP 2MCYA 1QUBA 3OEDC 4J38B 3CALA 3RJ3D 1G4FA 3M7PA 1H04P 3TVJA 5HYUB 3KXVA 2JGWA 1U5MA 3SW0X 3EJHA 1E8BA 2B5ID 1CKLA 1TPGA 1C1ZA 2EHFA 2XRDA 3NFPI 2W80A 1QGBA 2JRAA 2YBYA 2KRIA 2XWBF 1MD8A 2QY0A 1HFIA 4LOSA 1ELVA 3IU3I 4YNXA 4IGDA 1Z92B 2CG7A 2LOJA 4DJZA 1Q3XA 5HYTB 5HZPB 1GKNA 1FBRA 2XQWC 2RLQA 3R62A 2V8EA 1TPMA 1GPZA 3INBC 2IZ4A 3ZD2A 1O9AA 2XRBA 3OXUD 1E88A 1GKGA 4WJG2 3T5OA 1OK3A 1OK9A 5HYPA 2RL0A 2RLPA 4FXGG 4MUCA 4JHSA 1OK1A 5FO8C 3ZRZA 2YRAA 1LY2A 3OP8A 4F4OC 1HFHA 4ONTD 4AYMA 4B2RA 4PZ5A 1G4GA 2BZMA 2CG6A 2W81A 1GHQB 1E5GA 4AYIA 1OJVA 3KZJA 1OJYA
chains in the Genus database with same CATH superfamily
2ERJA 4A5WB 4AYEA 1OJWA 2G7IA 5I0QB 1SS2A 4B2SA 4CSYA 3FGTA 4K12A 3MQLA 3VWOA 2IZ3A 1H03P 1RLHA 1NWVA 4C16A 1MD7A 3IX0A 2WIIC 2I2LA 1VVCA 3GOVA 3ZD1A 2KMSA 3ZLDA 4LOTA 2UWNA 1OK2A 1HCCA 4AYDA 5JPMG 1SRZA 2A55A 1VVDA 1PPQA 2CKUA 3ERBA 5DN4A 1QO6A 2RKZA 3GXEA 3ZLEA 2Y8SA 1ZJKA 2JGXA 2MCZA 1TPNA 3F6KA 1UOTP 2RKYA 4ZH1D 1H2PP 2EC3A 3O8EB 2XWJI 2O39C 3L89M 4KKDA 1H2QP 2MCYA 3WSXA 2X2ZA 1QUBA 3OEDC 4J38B 3CALA 3RJ3D 1G4FA 3M7PA 1H04P 3TVJA 5HYUB 3KXVA 2JGWA 1U5MA 3SW0X 4APLA 3EJHA 1E8BA 2B5ID 1CKLA 5DN5A 1TPGA 1C1ZA 3FGRA 2EHFA 2XRDA 3NFPI 2W80A 1QGBA 2JRAA 4MSLA 2YBYA 2KRIA 2XWBF 1MD8A 2QY0A 2ZYCA 1HFIA 4LOSA 1ELVA 3IU3I 4YNXA 2Y8RA 4IGDA 1Z92B 2CG7A 2LOJA 3K3TA 1Q3XA 4DJZA 5HYTB 5HZPB 1FBRA 1GKNA 2XQWC 2RLQA 3R62A 2V8EA 1TPMA 1GPZA 3CI0J 4PO7A 2Y8TA 3INBC 2IZ4A 3ZD2A 1O9AA 2XRBA 3OXUD 1E88A 1GKGA 4WJG2 3T5OA 1OK3A 1OK9A 5HYPA 4N7EA 2RL0A 2RLPA 3WSYA 4FXGG 4MUCA 4JHSA 1OK1A 5FO8C 3ZRZA 2YRAA 3NJAA 1LY2A 3OP8A 4F4OC 4BWCA 1HFHA 4ONTD 4AYMA 4B2RA 4PZ5A 1G4GA 4YIZA 2BZMA 2CG6A 2W81A 1GHQB 1E5GA 4AYIA 1OJVA 3KZJA 1OJYA
chains in the Genus database with same CATH topology
2ERJA 4A5WB 4AYEA 1OJWA 2G7IA 5I0QB 1SS2A 4B2SA 4CSYA 4K12A 3MQLA 2IZ3A 1H03P 1NWVA 4C16A 1MD7A 3IX0A 2WIIC 1VVCA 3GOVA 3ZD1A 2KMSA 4LOTA 2UWNA 1OK2A 1HCCA 4AYDA 5JPMG 1SRZA 2A55A 1VVDA 1PPQA 2CKUA 3ERBA 1QO6A 2RKZA 3GXEA 1ZJKA 2JGXA 2MCZA 1TPNA 1UOTP 2RKYA 4ZH1D 1H2PP 2EC3A 3O8EB 2XWJI 2O39C 3L89M 4KKDA 1H2QP 2MCYA 1QUBA 3OEDC 4J38B 3CALA 3RJ3D 1G4FA 3M7PA 1H04P 3TVJA 5HYUB 3KXVA 2JGWA 1U5MA 3SW0X 3EJHA 1E8BA 2B5ID 1CKLA 1TPGA 1C1ZA 2EHFA 2XRDA 3NFPI 2W80A 1QGBA 2JRAA 2YBYA 2KRIA 2XWBF 1MD8A 2QY0A 1HFIA 4LOSA 1ELVA 3IU3I 4YNXA 4IGDA 1Z92B 2CG7A 2LOJA 4DJZA 1Q3XA 5HYTB 5HZPB 1GKNA 1FBRA 2XQWC 2RLQA 3R62A 2V8EA 1TPMA 1GPZA 3INBC 2IZ4A 3ZD2A 1O9AA 2XRBA 3OXUD 1E88A 1GKGA 4WJG2 3T5OA 1OK3A 1OK9A 5HYPA 2RL0A 2RLPA 4FXGG 4MUCA 4JHSA 1OK1A 5FO8C 3ZRZA 2YRAA 1LY2A 3OP8A 4F4OC 1HFHA 4ONTD 4AYMA 4B2RA 4PZ5A 1G4GA 2BZMA 2CG6A 2W81A 1GHQB 1E5GA 4AYIA 1OJVA 3KZJA 1OJYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ERJ A;  4A5W B;  4AYE A;  1OJW A;  2G7I A;  5I0Q B;  1SS2 A;  4B2S A;  4CSY A;  4K12 A;  3MQL A;  2IZ3 A;  1H03 P;  1NWV A;  4C16 A;  1MD7 A;  3IX0 A;  2WII C;  1VVC A;  3GOV A;  3ZD1 A;  2KMS A;  4LOT A;  2UWN A;  1OK2 A;  1HCC A;  4AYD A;  5JPM G;  1SRZ A;  2A55 A;  1VVD A;  1PPQ A;  2CKU A;  3ERB A;  1QO6 A;  2RKZ A;  3GXE A;  1ZJK A;  2JGX A;  2MCZ A;  1TPN A;  1UOT P;  2RKY A;  4ZH1 D;  1H2P P;  2EC3 A;  3O8E B;  2XWJ I;  2O39 C;  3L89 M;  4KKD A;  1H2Q P;  2MCY A;  1QUB A;  3OED C;  4J38 B;  3CAL A;  3RJ3 D;  1G4F A;  3M7P A;  1H04 P;  3TVJ A;  5HYU B;  3KXV A;  2JGW A;  1U5M A;  3SW0 X;  3EJH A;  1E8B A;  2B5I D;  1CKL A;  1TPG A;  1C1Z A;  2EHF A;  2XRD A;  3NFP I;  2W80 A;  1QGB A;  2JRA A;  2YBY A;  2KRI A;  2XWB F;  1MD8 A;  2QY0 A;  1HFI A;  4LOS A;  1ELV A;  3IU3 I;  4YNX A;  4IGD A;  1Z92 B;  2CG7 A;  2LOJ A;  4DJZ A;  1Q3X A;  5HYT B;  5HZP B;  1GKN A;  1FBR A;  2XQW C;  2RLQ A;  3R62 A;  2V8E A;  1TPM A;  1GPZ A;  3INB C;  2IZ4 A;  3ZD2 A;  1O9A A;  2XRB A;  3OXU D;  1E88 A;  1GKG A;  4WJG 2;  3T5O A;  1OK3 A;  1OK9 A;  5HYP A;  2RL0 A;  2RLP A;  4FXG G;  4MUC A;  4JHS A;  1OK1 A;  5FO8 C;  3ZRZ A;  2YRA A;  1LY2 A;  3OP8 A;  4F4O C;  1HFH A;  4ONT D;  4AYM A;  4B2R A;  4PZ5 A;  1G4G A;  2BZM A;  2CG6 A;  2W81 A;  1GHQ B;  1E5G A;  4AYI A;  1OJV A;  3KZJ A;  1OJY A; 
#chains in the Genus database with same CATH topology
 2ERJ A;  4A5W B;  4AYE A;  1OJW A;  2G7I A;  5I0Q B;  1SS2 A;  4B2S A;  4CSY A;  3FGT A;  4K12 A;  3MQL A;  3VWO A;  2IZ3 A;  1H03 P;  1RLH A;  1NWV A;  4C16 A;  1MD7 A;  3IX0 A;  2WII C;  2I2L A;  1VVC A;  3GOV A;  3ZD1 A;  2KMS A;  3ZLD A;  4LOT A;  2UWN A;  1OK2 A;  1HCC A;  4AYD A;  5JPM G;  1SRZ A;  2A55 A;  1VVD A;  1PPQ A;  2CKU A;  3ERB A;  5DN4 A;  1QO6 A;  2RKZ A;  3GXE A;  3ZLE A;  2Y8S A;  1ZJK A;  2JGX A;  2MCZ A;  1TPN A;  3F6K A;  1UOT P;  2RKY A;  4ZH1 D;  1H2P P;  2EC3 A;  3O8E B;  2XWJ I;  2O39 C;  3L89 M;  4KKD A;  1H2Q P;  2MCY A;  3WSX A;  2X2Z A;  1QUB A;  3OED C;  4J38 B;  3CAL A;  3RJ3 D;  1G4F A;  3M7P A;  1H04 P;  3TVJ A;  5HYU B;  3KXV A;  2JGW A;  1U5M A;  3SW0 X;  4APL A;  3EJH A;  1E8B A;  2B5I D;  1CKL A;  5DN5 A;  1TPG A;  1C1Z A;  3FGR A;  2EHF A;  2XRD A;  3NFP I;  2W80 A;  1QGB A;  2JRA A;  4MSL A;  2YBY A;  2KRI A;  2XWB F;  1MD8 A;  2QY0 A;  2ZYC A;  1HFI A;  4LOS A;  1ELV A;  3IU3 I;  4YNX A;  2Y8R A;  4IGD A;  1Z92 B;  2CG7 A;  2LOJ A;  3K3T A;  1Q3X A;  4DJZ A;  5HYT B;  5HZP B;  1FBR A;  1GKN A;  2XQW C;  2RLQ A;  3R62 A;  2V8E A;  1TPM A;  1GPZ A;  3CI0 J;  4PO7 A;  2Y8T A;  3INB C;  2IZ4 A;  3ZD2 A;  1O9A A;  2XRB A;  3OXU D;  1E88 A;  1GKG A;  4WJG 2;  3T5O A;  1OK3 A;  1OK9 A;  5HYP A;  4N7E A;  2RL0 A;  2RLP A;  3WSY A;  4FXG G;  4MUC A;  4JHS A;  1OK1 A;  5FO8 C;  3ZRZ A;  2YRA A;  3NJA A;  1LY2 A;  3OP8 A;  4F4O C;  4BWC A;  1HFH A;  4ONT D;  4AYM A;  4B2R A;  4PZ5 A;  1G4G A;  4YIZ A;  2BZM A;  2CG6 A;  2W81 A;  1GHQ B;  1E5G A;  4AYI A;  1OJV A;  3KZJ A;  1OJY A; 
#chains in the Genus database with same CATH homology
 2ERJ A;  4A5W B;  4AYE A;  1OJW A;  2G7I A;  5I0Q B;  1SS2 A;  4B2S A;  4CSY A;  4K12 A;  3MQL A;  2IZ3 A;  1H03 P;  1NWV A;  4C16 A;  1MD7 A;  3IX0 A;  2WII C;  1VVC A;  3GOV A;  3ZD1 A;  2KMS A;  4LOT A;  2UWN A;  1OK2 A;  1HCC A;  4AYD A;  5JPM G;  1SRZ A;  2A55 A;  1VVD A;  1PPQ A;  2CKU A;  3ERB A;  1QO6 A;  2RKZ A;  3GXE A;  1ZJK A;  2JGX A;  2MCZ A;  1TPN A;  1UOT P;  2RKY A;  4ZH1 D;  1H2P P;  2EC3 A;  3O8E B;  2XWJ I;  2O39 C;  3L89 M;  4KKD A;  1H2Q P;  2MCY A;  1QUB A;  3OED C;  4J38 B;  3CAL A;  3RJ3 D;  1G4F A;  3M7P A;  1H04 P;  3TVJ A;  5HYU B;  3KXV A;  2JGW A;  1U5M A;  3SW0 X;  3EJH A;  1E8B A;  2B5I D;  1CKL A;  1TPG A;  1C1Z A;  2EHF A;  2XRD A;  3NFP I;  2W80 A;  1QGB A;  2JRA A;  2YBY A;  2KRI A;  2XWB F;  1MD8 A;  2QY0 A;  1HFI A;  4LOS A;  1ELV A;  3IU3 I;  4YNX A;  4IGD A;  1Z92 B;  2CG7 A;  2LOJ A;  4DJZ A;  1Q3X A;  5HYT B;  5HZP B;  1GKN A;  1FBR A;  2XQW C;  2RLQ A;  3R62 A;  2V8E A;  1TPM A;  1GPZ A;  3INB C;  2IZ4 A;  3ZD2 A;  1O9A A;  2XRB A;  3OXU D;  1E88 A;  1GKG A;  4WJG 2;  3T5O A;  1OK3 A;  1OK9 A;  5HYP A;  2RL0 A;  2RLP A;  4FXG G;  4MUC A;  4JHS A;  1OK1 A;  5FO8 C;  3ZRZ A;  2YRA A;  1LY2 A;  3OP8 A;  4F4O C;  1HFH A;  4ONT D;  4AYM A;  4B2R A;  4PZ5 A;  1G4G A;  2BZM A;  2CG6 A;  2W81 A;  1GHQ B;  1E5G A;  4AYI A;  1OJV A;  3KZJ A;  1OJY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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