1OJYA

Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
252
structure length
252
Chain Sequence
QDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
pubmed doi rcsb
molecule tags Regulator of complement pathway
source organism Homo sapiens
molecule keywords COMPLEMENT DECAY-ACCELERATING FACTOR
total genus 40
structure length 252
sequence length 252
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2003-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojyA04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojyA03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojyA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojyA02
4AYMA 1H03P 3TVJA 5HYUB 2W80A 4K12A 3OEDC 4LOSA 2JGWA 2RL0A 4WJG2 1CKLA 5HYPA 5I0QB 1H2QP 2IZ4A 1NWVA 1SS2A 4MUCA 2CKUA 3T5OA 3M7PA 3EJHA 4A5WB 3O8EB 4J38B 4DJZA 1G4GA 3GXEA 2JGXA 2RLQA 2KRIA 5JPMG 1HFHA 2LOJA 4F4OC 5HZPB 4LOTA 3KZJA 3MQLA 2MCYA 2XWJI 3ERBA 1HFIA 2B5ID 1Q3XA 2XQWC 1MD8A 1TPNA 4B2RA 3NFPI 1E5GA 4ZH1D 4CSYA 1Z92B 1G4FA 1GPZA 3OXUD 1H04P 1ZJKA 2UWNA 5HYTB 1OJVA 1PPQA 1UOTP 2W81A 2QY0A 3ZD1A 1E88A 2A55A 2BZMA 1FBRA 4KKDA 2G7IA 1OK1A 2JRAA 1SRZA 3OP8A 2EHFA 4ONTD 3ZRZA 4YNXA 1E8BA 2RLPA 2XRBA 1U5MA 1TPGA 4PZ5A 2YRAA 1ELVA 2CG7A 2YBYA 3L89M 3CALA 2XRDA 1GKGA 1LY2A 2IZ3A 1OK2A 3KXVA 3GOVA 2CG6A 1GHQB 1OK9A 3INBC 4JHSA 3SW0X 2XWBF 1OK3A 1H2PP 1C1ZA 1GKNA 3IU3I 1VVDA 4FXGG 3ZD2A 2RKYA 3IX0A 2WIIC 2V8EA 4IGDA 4AYIA 2ERJA 4AYEA 5FO8C 1OJYA 1QGBA 2KMSA 3R62A 1HCCA 1TPMA 1QO6A 1MD7A 1QUBA 1O9AA 1OJWA 2MCZA 3RJ3D 2O39C 2EC3A 4AYDA 4C16A 4B2SA 1VVCA 2RKZA
chains in the Genus database with same CATH superfamily
4AYMA 1H03P 3TVJA 5HYUB 4PO7A 2W80A 4K12A 3OEDC 4LOSA 2JGWA 3WSYA 2RL0A 4WJG2 1CKLA 5HYPA 5I0QB 1H2QP 2IZ4A 1NWVA 1SS2A 4MUCA 2CKUA 3T5OA 3M7PA 3EJHA 4A5WB 2Y8RA 3O8EB 4J38B 4DJZA 1G4GA 3GXEA 2JGXA 2RLQA 2KRIA 5JPMG 1HFHA 2LOJA 5DN4A 4F4OC 5HZPB 3CI0J 4LOTA 3KZJA 3MQLA 2MCYA 3WSXA 4YIZA 2XWJI 3ERBA 1HFIA 2B5ID 1Q3XA 2XQWC 1MD8A 1TPNA 4B2RA 3NFPI 1E5GA 4ZH1D 2Y8SA 1Z92B 4CSYA 1G4FA 1GPZA 3OXUD 1H04P 1ZJKA 2ZYCA 2UWNA 5HYTB 1OJVA 5DN5A 1PPQA 1UOTP 2W81A 2QY0A 4N7EA 3ZD1A 1E88A 2A55A 2BZMA 1FBRA 4KKDA 2G7IA 1OK1A 2JRAA 1SRZA 3ZLEA 3OP8A 2EHFA 2I2LA 4ONTD 3ZRZA 2Y8TA 4YNXA 1E8BA 2RLPA 2XRBA 1U5MA 1TPGA 4PZ5A 2YRAA 1ELVA 2CG7A 2YBYA 3L89M 3CALA 2XRDA 3K3TA 3F6KA 1GKGA 1LY2A 3FGRA 3NJAA 2IZ3A 1OK2A 3KXVA 3GOVA 2CG6A 1GHQB 1OK9A 3INBC 4JHSA 4MSLA 3SW0X 2XWBF 1OK3A 1H2PP 1C1ZA 1GKNA 3IU3I 1VVDA 4FXGG 3ZD2A 2RKYA 3IX0A 2WIIC 2V8EA 3VWOA 3FGTA 4APLA 1RLHA 4IGDA 4AYIA 2X2ZA 2ERJA 4AYEA 5FO8C 1OJYA 1QGBA 2KMSA 3R62A 1HCCA 1TPMA 1QO6A 1MD7A 1QUBA 1O9AA 1OJWA 2MCZA 3RJ3D 2O39C 2EC3A 4AYDA 4C16A 4B2SA 1VVCA 4BWCA 2RKZA 3ZLDA
chains in the Genus database with same CATH topology
4AYMA 1H03P 3TVJA 5HYUB 2W80A 4K12A 3OEDC 4LOSA 2JGWA 2RL0A 4WJG2 1CKLA 5HYPA 5I0QB 1H2QP 2IZ4A 1NWVA 1SS2A 4MUCA 2CKUA 3T5OA 3M7PA 3EJHA 4A5WB 3O8EB 4J38B 4DJZA 1G4GA 3GXEA 2JGXA 2RLQA 2KRIA 5JPMG 1HFHA 2LOJA 4F4OC 5HZPB 4LOTA 3KZJA 3MQLA 2MCYA 2XWJI 3ERBA 1HFIA 2B5ID 1Q3XA 2XQWC 1MD8A 1TPNA 4B2RA 3NFPI 1E5GA 4ZH1D 4CSYA 1Z92B 1G4FA 1GPZA 3OXUD 1H04P 1ZJKA 2UWNA 5HYTB 1OJVA 1PPQA 1UOTP 2W81A 2QY0A 3ZD1A 1E88A 2A55A 2BZMA 1FBRA 4KKDA 2G7IA 1OK1A 2JRAA 1SRZA 3OP8A 2EHFA 4ONTD 3ZRZA 4YNXA 1E8BA 2RLPA 2XRBA 1U5MA 1TPGA 4PZ5A 2YRAA 1ELVA 2CG7A 2YBYA 3L89M 3CALA 2XRDA 1GKGA 1LY2A 2IZ3A 1OK2A 3KXVA 3GOVA 2CG6A 1GHQB 1OK9A 3INBC 4JHSA 3SW0X 2XWBF 1OK3A 1H2PP 1C1ZA 1GKNA 3IU3I 1VVDA 4FXGG 3ZD2A 2RKYA 3IX0A 2WIIC 2V8EA 4IGDA 4AYIA 2ERJA 4AYEA 5FO8C 1OJYA 1QGBA 2KMSA 3R62A 1HCCA 1TPMA 1QO6A 1MD7A 1QUBA 1O9AA 1OJWA 2MCZA 3RJ3D 2O39C 2EC3A 4AYDA 4C16A 4B2SA 1VVCA 2RKZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AYM A;  1H03 P;  3TVJ A;  5HYU B;  2W80 A;  4K12 A;  3OED C;  4LOS A;  2JGW A;  2RL0 A;  4WJG 2;  1CKL A;  5HYP A;  5I0Q B;  1H2Q P;  2IZ4 A;  1NWV A;  1SS2 A;  4MUC A;  2CKU A;  3T5O A;  3M7P A;  3EJH A;  4A5W B;  3O8E B;  4J38 B;  4DJZ A;  1G4G A;  3GXE A;  2JGX A;  2RLQ A;  2KRI A;  5JPM G;  1HFH A;  2LOJ A;  4F4O C;  5HZP B;  4LOT A;  3KZJ A;  3MQL A;  2MCY A;  2XWJ I;  3ERB A;  1HFI A;  2B5I D;  1Q3X A;  2XQW C;  1MD8 A;  1TPN A;  4B2R A;  3NFP I;  1E5G A;  4ZH1 D;  4CSY A;  1Z92 B;  1G4F A;  1GPZ A;  3OXU D;  1H04 P;  1ZJK A;  2UWN A;  5HYT B;  1OJV A;  1PPQ A;  1UOT P;  2W81 A;  2QY0 A;  3ZD1 A;  1E88 A;  2A55 A;  2BZM A;  1FBR A;  4KKD A;  2G7I A;  1OK1 A;  2JRA A;  1SRZ A;  3OP8 A;  2EHF A;  4ONT D;  3ZRZ A;  4YNX A;  1E8B A;  2RLP A;  2XRB A;  1U5M A;  1TPG A;  4PZ5 A;  2YRA A;  1ELV A;  2CG7 A;  2YBY A;  3L89 M;  3CAL A;  2XRD A;  1GKG A;  1LY2 A;  2IZ3 A;  1OK2 A;  3KXV A;  3GOV A;  2CG6 A;  1GHQ B;  1OK9 A;  3INB C;  4JHS A;  3SW0 X;  2XWB F;  1OK3 A;  1H2P P;  1C1Z A;  1GKN A;  3IU3 I;  1VVD A;  4FXG G;  3ZD2 A;  2RKY A;  3IX0 A;  2WII C;  2V8E A;  4IGD A;  4AYI A;  2ERJ A;  4AYE A;  5FO8 C;  1OJY A;  1QGB A;  2KMS A;  3R62 A;  1HCC A;  1TPM A;  1QO6 A;  1MD7 A;  1QUB A;  1O9A A;  1OJW A;  2MCZ A;  3RJ3 D;  2O39 C;  2EC3 A;  4AYD A;  4C16 A;  4B2S A;  1VVC A;  2RKZ A; 
#chains in the Genus database with same CATH topology
 4AYM A;  1H03 P;  3TVJ A;  5HYU B;  4PO7 A;  2W80 A;  4K12 A;  3OED C;  4LOS A;  2JGW A;  3WSY A;  2RL0 A;  4WJG 2;  1CKL A;  5HYP A;  5I0Q B;  1H2Q P;  2IZ4 A;  1NWV A;  1SS2 A;  4MUC A;  2CKU A;  3T5O A;  3M7P A;  3EJH A;  4A5W B;  2Y8R A;  3O8E B;  4J38 B;  4DJZ A;  1G4G A;  3GXE A;  2JGX A;  2RLQ A;  2KRI A;  5JPM G;  1HFH A;  2LOJ A;  5DN4 A;  4F4O C;  5HZP B;  3CI0 J;  4LOT A;  3KZJ A;  3MQL A;  2MCY A;  3WSX A;  4YIZ A;  2XWJ I;  3ERB A;  1HFI A;  2B5I D;  1Q3X A;  2XQW C;  1MD8 A;  1TPN A;  4B2R A;  3NFP I;  1E5G A;  4ZH1 D;  2Y8S A;  1Z92 B;  4CSY A;  1G4F A;  1GPZ A;  3OXU D;  1H04 P;  1ZJK A;  2ZYC A;  2UWN A;  5HYT B;  1OJV A;  5DN5 A;  1PPQ A;  1UOT P;  2W81 A;  2QY0 A;  4N7E A;  3ZD1 A;  1E88 A;  2A55 A;  2BZM A;  1FBR A;  4KKD A;  2G7I A;  1OK1 A;  2JRA A;  1SRZ A;  3ZLE A;  3OP8 A;  2EHF A;  2I2L A;  4ONT D;  3ZRZ A;  2Y8T A;  4YNX A;  1E8B A;  2RLP A;  2XRB A;  1U5M A;  1TPG A;  4PZ5 A;  2YRA A;  1ELV A;  2CG7 A;  2YBY A;  3L89 M;  3CAL A;  2XRD A;  3K3T A;  3F6K A;  1GKG A;  1LY2 A;  3FGR A;  3NJA A;  2IZ3 A;  1OK2 A;  3KXV A;  3GOV A;  2CG6 A;  1GHQ B;  1OK9 A;  3INB C;  4JHS A;  4MSL A;  3SW0 X;  2XWB F;  1OK3 A;  1H2P P;  1C1Z A;  1GKN A;  3IU3 I;  1VVD A;  4FXG G;  3ZD2 A;  2RKY A;  3IX0 A;  2WII C;  2V8E A;  3VWO A;  3FGT A;  4APL A;  1RLH A;  4IGD A;  4AYI A;  2X2Z A;  2ERJ A;  4AYE A;  5FO8 C;  1OJY A;  1QGB A;  2KMS A;  3R62 A;  1HCC A;  1TPM A;  1QO6 A;  1MD7 A;  1QUB A;  1O9A A;  1OJW A;  2MCZ A;  3RJ3 D;  2O39 C;  2EC3 A;  4AYD A;  4C16 A;  4B2S A;  1VVC A;  4BWC A;  2RKZ A;  3ZLD A; 
#chains in the Genus database with same CATH homology
 4AYM A;  1H03 P;  3TVJ A;  5HYU B;  2W80 A;  4K12 A;  3OED C;  4LOS A;  2JGW A;  2RL0 A;  4WJG 2;  1CKL A;  5HYP A;  5I0Q B;  1H2Q P;  2IZ4 A;  1NWV A;  1SS2 A;  4MUC A;  2CKU A;  3T5O A;  3M7P A;  3EJH A;  4A5W B;  3O8E B;  4J38 B;  4DJZ A;  1G4G A;  3GXE A;  2JGX A;  2RLQ A;  2KRI A;  5JPM G;  1HFH A;  2LOJ A;  4F4O C;  5HZP B;  4LOT A;  3KZJ A;  3MQL A;  2MCY A;  2XWJ I;  3ERB A;  1HFI A;  2B5I D;  1Q3X A;  2XQW C;  1MD8 A;  1TPN A;  4B2R A;  3NFP I;  1E5G A;  4ZH1 D;  4CSY A;  1Z92 B;  1G4F A;  1GPZ A;  3OXU D;  1H04 P;  1ZJK A;  2UWN A;  5HYT B;  1OJV A;  1PPQ A;  1UOT P;  2W81 A;  2QY0 A;  3ZD1 A;  1E88 A;  2A55 A;  2BZM A;  1FBR A;  4KKD A;  2G7I A;  1OK1 A;  2JRA A;  1SRZ A;  3OP8 A;  2EHF A;  4ONT D;  3ZRZ A;  4YNX A;  1E8B A;  2RLP A;  2XRB A;  1U5M A;  1TPG A;  4PZ5 A;  2YRA A;  1ELV A;  2CG7 A;  2YBY A;  3L89 M;  3CAL A;  2XRD A;  1GKG A;  1LY2 A;  2IZ3 A;  1OK2 A;  3KXV A;  3GOV A;  2CG6 A;  1GHQ B;  1OK9 A;  3INB C;  4JHS A;  3SW0 X;  2XWB F;  1OK3 A;  1H2P P;  1C1Z A;  1GKN A;  3IU3 I;  1VVD A;  4FXG G;  3ZD2 A;  2RKY A;  3IX0 A;  2WII C;  2V8E A;  4IGD A;  4AYI A;  2ERJ A;  4AYE A;  5FO8 C;  1OJY A;  1QGB A;  2KMS A;  3R62 A;  1HCC A;  1TPM A;  1QO6 A;  1MD7 A;  1QUB A;  1O9A A;  1OJW A;  2MCZ A;  3RJ3 D;  2O39 C;  2EC3 A;  4AYD A;  4C16 A;  4B2S A;  1VVC A;  2RKZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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