2KRIA

Structure of a complex between domain v of beta2-glycoprotein i and the fourth ligand-binding module from ldlr determined with haddock
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
82
structure length
82
Chain Sequence
CKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mode of interaction between beta2GPI and lipoprotein receptors suggests mutually exclusive binding of beta2GPI to the receptors and anionic phospholipids.
pubmed doi rcsb
molecule tags Protein binding/endocytosis
source organism Homo sapiens
molecule keywords Beta-2-glycoprotein 1
total genus 11
structure length 82
sequence length 82
ec nomenclature
pdb deposition date 2009-12-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2kriA00
3ZD2A 5HZPB 4LOSA 2MCYA 4CSYA 1OJVA 1TPGA 4DJZA 3GOVA 2CKUA 4C16A 2WIIC 3KZJA 2EC3A 4AYIA 3R62A 1MD8A 4ZH1D 2O39C 1O9AA 5HYUB 3SW0X 4AYDA 3OP8A 1GPZA 2BZMA 3NFPI 2ERJA 2UWNA 1GKGA 1C1ZA 4JHSA 4ONTD 3L89M 3OXUD 3TVJA 3ZD1A 1H03P 2JGXA 4WJG2 2QY0A 2KRIA 1MD7A 4FXGG 2G7IA 2A55A 2IZ3A 1SRZA 4J38B 4K12A 1H2PP 1OJYA 3MQLA 2CG6A 1U5MA 2V8EA 1CKLA 1LY2A 1OJWA 4B2RA 5HYPA 4LOTA 2RLQA 1E5GA 1Z92B 1OK2A 5FO8C 1QGBA 2JRAA 1QO6A 1VVCA 4KKDA 3T5OA 3GXEA 3EJHA 5HYTB 2W81A 1HFIA 2XRBA 2XWJI 2RL0A 2XWBF 2YRAA 2RLPA 1E88A 2RKYA 2XRDA 2IZ4A 1QUBA 1TPMA 1TPNA 1H04P 3IU3I 1Q3XA 1OK9A 2CG7A 1HFHA 4AYEA 3KXVA 4F4OC 3ZRZA 1VVDA 1ZJKA 2W80A 4YNXA 3RJ3D 3CALA 1HCCA 1GHQB 1ELVA 1OK3A 4A5WB 1FBRA 5I0QB 5JPMG 4PZ5A 4B2SA 2XQWC 2B5ID 2LOJA 4IGDA 1G4FA 1H2QP 2JGWA 1PPQA 2MCZA 2YBYA 3O8EB 1OK1A 2EHFA 3IX0A 1NWVA 1G4GA 2KMSA 3ERBA 1GKNA 3INBC 1E8BA 4AYMA 1UOTP 1SS2A 4MUCA 3OEDC 2RKZA 3M7PA
chains in the Genus database with same CATH superfamily
3ZD2A 3F6KA 5HZPB 4LOSA 2MCYA 4CSYA 1OJVA 1TPGA 4DJZA 3GOVA 2CKUA 2Y8TA 4C16A 2WIIC 3WSXA 3KZJA 2EC3A 4AYIA 3R62A 5DN4A 1MD8A 4ZH1D 2O39C 1O9AA 5HYUB 3FGTA 3SW0X 4AYDA 3OP8A 1RLHA 1GPZA 2BZMA 3NFPI 2ERJA 2X2ZA 2UWNA 1GKGA 1C1ZA 4JHSA 4ONTD 3L89M 4APLA 2ZYCA 3OXUD 3TVJA 3ZD1A 1H03P 2Y8RA 2JGXA 4WJG2 2QY0A 3K3TA 2KRIA 1MD7A 4FXGG 2G7IA 2A55A 2IZ3A 1SRZA 4J38B 4K12A 1H2PP 1OJYA 3MQLA 2CG6A 1U5MA 2V8EA 1CKLA 1LY2A 2Y8SA 1OJWA 4B2RA 5HYPA 4LOTA 2RLQA 3FGRA 3ZLEA 1Z92B 1E5GA 1OK2A 5FO8C 1QGBA 2JRAA 1QO6A 4PO7A 4YIZA 1VVCA 3ZLDA 4KKDA 3T5OA 3GXEA 3WSYA 3VWOA 3EJHA 5HYTB 2I2LA 1HFIA 2W81A 2XRBA 2XWJI 3NJAA 2RL0A 2XWBF 2YRAA 2RLPA 1E88A 2RKYA 2XRDA 4MSLA 2IZ4A 1QUBA 1TPMA 1TPNA 1H04P 3IU3I 1Q3XA 1OK9A 4N7EA 2CG7A 1HFHA 4AYEA 3KXVA 4F4OC 3ZRZA 1VVDA 1ZJKA 2W80A 4YNXA 3RJ3D 3CALA 1HCCA 1GHQB 1ELVA 1OK3A 4A5WB 1FBRA 5I0QB 5JPMG 4PZ5A 4B2SA 2XQWC 5DN5A 2B5ID 2LOJA 4IGDA 4BWCA 1G4FA 1H2QP 2JGWA 1PPQA 2MCZA 2YBYA 3O8EB 3CI0J 1OK1A 2EHFA 3IX0A 1NWVA 1G4GA 2KMSA 3ERBA 1GKNA 3INBC 1E8BA 4AYMA 1UOTP 1SS2A 4MUCA 3OEDC 2RKZA 3M7PA
chains in the Genus database with same CATH topology
3ZD2A 5HZPB 4LOSA 2MCYA 4CSYA 1OJVA 1TPGA 4DJZA 3GOVA 2CKUA 4C16A 2WIIC 3KZJA 2EC3A 4AYIA 3R62A 1MD8A 4ZH1D 2O39C 1O9AA 5HYUB 3SW0X 4AYDA 3OP8A 1GPZA 2BZMA 3NFPI 2ERJA 2UWNA 1GKGA 1C1ZA 4JHSA 4ONTD 3L89M 3OXUD 3TVJA 3ZD1A 1H03P 2JGXA 4WJG2 2QY0A 2KRIA 1MD7A 4FXGG 2G7IA 2A55A 2IZ3A 1SRZA 4J38B 4K12A 1H2PP 1OJYA 3MQLA 2CG6A 1U5MA 2V8EA 1CKLA 1LY2A 1OJWA 4B2RA 5HYPA 4LOTA 2RLQA 1E5GA 1Z92B 1OK2A 5FO8C 1QGBA 2JRAA 1QO6A 1VVCA 4KKDA 3T5OA 3GXEA 3EJHA 5HYTB 2W81A 1HFIA 2XRBA 2XWJI 2RL0A 2XWBF 2YRAA 2RLPA 1E88A 2RKYA 2XRDA 2IZ4A 1QUBA 1TPMA 1TPNA 1H04P 3IU3I 1Q3XA 1OK9A 2CG7A 1HFHA 4AYEA 3KXVA 4F4OC 3ZRZA 1VVDA 1ZJKA 2W80A 4YNXA 3RJ3D 3CALA 1HCCA 1GHQB 1ELVA 1OK3A 4A5WB 1FBRA 5I0QB 5JPMG 4PZ5A 4B2SA 2XQWC 2B5ID 2LOJA 4IGDA 1G4FA 1H2QP 2JGWA 1PPQA 2MCZA 2YBYA 3O8EB 1OK1A 2EHFA 3IX0A 1NWVA 1G4GA 2KMSA 3ERBA 1GKNA 3INBC 1E8BA 4AYMA 1UOTP 1SS2A 4MUCA 3OEDC 2RKZA 3M7PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZD2 A;  5HZP B;  4LOS A;  2MCY A;  4CSY A;  1OJV A;  1TPG A;  4DJZ A;  3GOV A;  2CKU A;  4C16 A;  2WII C;  3KZJ A;  2EC3 A;  4AYI A;  3R62 A;  1MD8 A;  4ZH1 D;  2O39 C;  1O9A A;  5HYU B;  3SW0 X;  4AYD A;  3OP8 A;  1GPZ A;  2BZM A;  3NFP I;  2ERJ A;  2UWN A;  1GKG A;  1C1Z A;  4JHS A;  4ONT D;  3L89 M;  3OXU D;  3TVJ A;  3ZD1 A;  1H03 P;  2JGX A;  4WJG 2;  2QY0 A;  2KRI A;  1MD7 A;  4FXG G;  2G7I A;  2A55 A;  2IZ3 A;  1SRZ A;  4J38 B;  4K12 A;  1H2P P;  1OJY A;  3MQL A;  2CG6 A;  1U5M A;  2V8E A;  1CKL A;  1LY2 A;  1OJW A;  4B2R A;  5HYP A;  4LOT A;  2RLQ A;  1E5G A;  1Z92 B;  1OK2 A;  5FO8 C;  1QGB A;  2JRA A;  1QO6 A;  1VVC A;  4KKD A;  3T5O A;  3GXE A;  3EJH A;  5HYT B;  2W81 A;  1HFI A;  2XRB A;  2XWJ I;  2RL0 A;  2XWB F;  2YRA A;  2RLP A;  1E88 A;  2RKY A;  2XRD A;  2IZ4 A;  1QUB A;  1TPM A;  1TPN A;  1H04 P;  3IU3 I;  1Q3X A;  1OK9 A;  2CG7 A;  1HFH A;  4AYE A;  3KXV A;  4F4O C;  3ZRZ A;  1VVD A;  1ZJK A;  2W80 A;  4YNX A;  3RJ3 D;  3CAL A;  1HCC A;  1GHQ B;  1ELV A;  1OK3 A;  4A5W B;  1FBR A;  5I0Q B;  5JPM G;  4PZ5 A;  4B2S A;  2XQW C;  2B5I D;  2LOJ A;  4IGD A;  1G4F A;  1H2Q P;  2JGW A;  1PPQ A;  2MCZ A;  2YBY A;  3O8E B;  1OK1 A;  2EHF A;  3IX0 A;  1NWV A;  1G4G A;  2KMS A;  3ERB A;  1GKN A;  3INB C;  1E8B A;  4AYM A;  1UOT P;  1SS2 A;  4MUC A;  3OED C;  2RKZ A;  3M7P A; 
#chains in the Genus database with same CATH topology
 3ZD2 A;  3F6K A;  5HZP B;  4LOS A;  2MCY A;  4CSY A;  1OJV A;  1TPG A;  4DJZ A;  3GOV A;  2CKU A;  2Y8T A;  4C16 A;  2WII C;  3WSX A;  3KZJ A;  2EC3 A;  4AYI A;  3R62 A;  5DN4 A;  1MD8 A;  4ZH1 D;  2O39 C;  1O9A A;  5HYU B;  3FGT A;  3SW0 X;  4AYD A;  3OP8 A;  1RLH A;  1GPZ A;  2BZM A;  3NFP I;  2ERJ A;  2X2Z A;  2UWN A;  1GKG A;  1C1Z A;  4JHS A;  4ONT D;  3L89 M;  4APL A;  2ZYC A;  3OXU D;  3TVJ A;  3ZD1 A;  1H03 P;  2Y8R A;  2JGX A;  4WJG 2;  2QY0 A;  3K3T A;  2KRI A;  1MD7 A;  4FXG G;  2G7I A;  2A55 A;  2IZ3 A;  1SRZ A;  4J38 B;  4K12 A;  1H2P P;  1OJY A;  3MQL A;  2CG6 A;  1U5M A;  2V8E A;  1CKL A;  1LY2 A;  2Y8S A;  1OJW A;  4B2R A;  5HYP A;  4LOT A;  2RLQ A;  3FGR A;  3ZLE A;  1Z92 B;  1E5G A;  1OK2 A;  5FO8 C;  1QGB A;  2JRA A;  1QO6 A;  4PO7 A;  4YIZ A;  1VVC A;  3ZLD A;  4KKD A;  3T5O A;  3GXE A;  3WSY A;  3VWO A;  3EJH A;  5HYT B;  2I2L A;  1HFI A;  2W81 A;  2XRB A;  2XWJ I;  3NJA A;  2RL0 A;  2XWB F;  2YRA A;  2RLP A;  1E88 A;  2RKY A;  2XRD A;  4MSL A;  2IZ4 A;  1QUB A;  1TPM A;  1TPN A;  1H04 P;  3IU3 I;  1Q3X A;  1OK9 A;  4N7E A;  2CG7 A;  1HFH A;  4AYE A;  3KXV A;  4F4O C;  3ZRZ A;  1VVD A;  1ZJK A;  2W80 A;  4YNX A;  3RJ3 D;  3CAL A;  1HCC A;  1GHQ B;  1ELV A;  1OK3 A;  4A5W B;  1FBR A;  5I0Q B;  5JPM G;  4PZ5 A;  4B2S A;  2XQW C;  5DN5 A;  2B5I D;  2LOJ A;  4IGD A;  4BWC A;  1G4F A;  1H2Q P;  2JGW A;  1PPQ A;  2MCZ A;  2YBY A;  3O8E B;  3CI0 J;  1OK1 A;  2EHF A;  3IX0 A;  1NWV A;  1G4G A;  2KMS A;  3ERB A;  1GKN A;  3INB C;  1E8B A;  4AYM A;  1UOT P;  1SS2 A;  4MUC A;  3OED C;  2RKZ A;  3M7P A; 
#chains in the Genus database with same CATH homology
 3ZD2 A;  5HZP B;  4LOS A;  2MCY A;  4CSY A;  1OJV A;  1TPG A;  4DJZ A;  3GOV A;  2CKU A;  4C16 A;  2WII C;  3KZJ A;  2EC3 A;  4AYI A;  3R62 A;  1MD8 A;  4ZH1 D;  2O39 C;  1O9A A;  5HYU B;  3SW0 X;  4AYD A;  3OP8 A;  1GPZ A;  2BZM A;  3NFP I;  2ERJ A;  2UWN A;  1GKG A;  1C1Z A;  4JHS A;  4ONT D;  3L89 M;  3OXU D;  3TVJ A;  3ZD1 A;  1H03 P;  2JGX A;  4WJG 2;  2QY0 A;  2KRI A;  1MD7 A;  4FXG G;  2G7I A;  2A55 A;  2IZ3 A;  1SRZ A;  4J38 B;  4K12 A;  1H2P P;  1OJY A;  3MQL A;  2CG6 A;  1U5M A;  2V8E A;  1CKL A;  1LY2 A;  1OJW A;  4B2R A;  5HYP A;  4LOT A;  2RLQ A;  1E5G A;  1Z92 B;  1OK2 A;  5FO8 C;  1QGB A;  2JRA A;  1QO6 A;  1VVC A;  4KKD A;  3T5O A;  3GXE A;  3EJH A;  5HYT B;  2W81 A;  1HFI A;  2XRB A;  2XWJ I;  2RL0 A;  2XWB F;  2YRA A;  2RLP A;  1E88 A;  2RKY A;  2XRD A;  2IZ4 A;  1QUB A;  1TPM A;  1TPN A;  1H04 P;  3IU3 I;  1Q3X A;  1OK9 A;  2CG7 A;  1HFH A;  4AYE A;  3KXV A;  4F4O C;  3ZRZ A;  1VVD A;  1ZJK A;  2W80 A;  4YNX A;  3RJ3 D;  3CAL A;  1HCC A;  1GHQ B;  1ELV A;  1OK3 A;  4A5W B;  1FBR A;  5I0Q B;  5JPM G;  4PZ5 A;  4B2S A;  2XQW C;  2B5I D;  2LOJ A;  4IGD A;  1G4F A;  1H2Q P;  2JGW A;  1PPQ A;  2MCZ A;  2YBY A;  3O8E B;  1OK1 A;  2EHF A;  3IX0 A;  1NWV A;  1G4G A;  2KMS A;  3ERB A;  1GKN A;  3INB C;  1E8B A;  4AYM A;  1UOT P;  1SS2 A;  4MUC A;  3OED C;  2RKZ A;  3M7P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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