2W81A

Structure of a complex between neisseria meningitidis factor h binding protein and ccps 6-7 of human complement factor h
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
119
structure length
115
Chain Sequence
CDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHYALKAQTVTCMENGWSPTPRCI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords COMPLEMENT FACTOR H
total genus 24
structure length 115
sequence length 119
chains with identical sequence B, E
ec nomenclature
pdb deposition date 2009-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2w81A02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2w81A01
1E8BA 3TVJA 5HYUB 1GHQB 2W81A 1ELVA 2EC3A 5I0QB 3OP8A 1TPMA 2IZ3A 3T5OA 2RKYA 3ZD1A 1QGBA 2XWJI 2RLQA 2XRDA 1QUBA 1HCCA 2ERJA 4PZ5A 1E5GA 2CG7A 4JHSA 1SS2A 4ONTD 2CG6A 2LOJA 3IX0A 1OK9A 1H04P 3NFPI 4YNXA 2YRAA 3ZD2A 1LY2A 1H2PP 5HZPB 1OJVA 4AYMA 2JRAA 3RJ3D 4AYDA 1OK1A 3SW0X 1CKLA 1OK2A 1HFHA 3OXUD 1OJWA 1O9AA 1TPNA 2KMSA 1GPZA 2JGXA 3CALA 3KZJA 1E88A 1MD8A 1G4GA 5HYPA 3GOVA 4CSYA 2B5ID 4DJZA 4AYEA 3INBC 1PPQA 2MCYA 4A5WB 3O8EB 2CKUA 1VVDA 1HFIA 2QY0A 1U5MA 5HYTB 2O39C 2XQWC 4LOTA 3KXVA 1C1ZA 4KKDA 4LOSA 1TPGA 4J38B 1Z92B 3M7PA 3ZRZA 4B2RA 3OEDC 2BZMA 1H2QP 5JPMG 2XWBF 2YBYA 4ZH1D 3MQLA 1SRZA 3EJHA 2RL0A 2RKZA 4C16A 1QO6A 3L89M 4K12A 1GKGA 2G7IA 2UWNA 3R62A 4AYIA 1GKNA 4WJG2 2WIIC 2KRIA 1NWVA 1MD7A 2V8EA 3GXEA 2W80A 1G4FA 1VVCA 3IU3I 2EHFA 2XRBA 1OK3A 1FBRA 4B2SA 4MUCA 2JGWA 1UOTP 1OJYA 5FO8C 1H03P 4FXGG 3ERBA 2A55A 4IGDA 1Q3XA 2RLPA 2IZ4A 4F4OC 2MCZA 1ZJKA
chains in the Genus database with same CATH superfamily
1E8BA 3TVJA 5HYUB 3VWOA 1GHQB 2W81A 1ELVA 2EC3A 5I0QB 2ZYCA 3OP8A 1TPMA 2IZ3A 3T5OA 2RKYA 3FGTA 3ZD1A 2Y8RA 1QGBA 2XWJI 2RLQA 2XRDA 1QUBA 1HCCA 2ERJA 2Y8SA 4PZ5A 2CG7A 4JHSA 1E5GA 1SS2A 4ONTD 2CG6A 2LOJA 3IX0A 1OK9A 3F6KA 1H04P 3NFPI 4YNXA 2YRAA 3ZD2A 1LY2A 1H2PP 5HZPB 1OJVA 4AYMA 3ZLDA 2JRAA 3RJ3D 4AYDA 1OK1A 3SW0X 1CKLA 1OK2A 1HFHA 3OXUD 1OJWA 1O9AA 1TPNA 2KMSA 1GPZA 2JGXA 3CALA 3KZJA 5DN5A 1E88A 1MD8A 1G4GA 5HYPA 3GOVA 4CSYA 2B5ID 5DN4A 4DJZA 4AYEA 4C16A 2I2LA 3INBC 1PPQA 2MCYA 4A5WB 3O8EB 2CKUA 1VVDA 1HFIA 2QY0A 1U5MA 5HYTB 2O39C 2XQWC 4LOTA 3WSXA 3KXVA 1C1ZA 4KKDA 4LOSA 1TPGA 2Y8TA 4J38B 1Z92B 4APLA 3M7PA 3ZRZA 4B2RA 3OEDC 2BZMA 1H2QP 5JPMG 2XWBF 2YBYA 4ZH1D 4BWCA 3MQLA 4YIZA 1SRZA 3EJHA 2RL0A 2RKZA 3K3TA 1QO6A 1RLHA 3L89M 3FGRA 2G7IA 2UWNA 3R62A 4K12A 4PO7A 4AYIA 1GKGA 1GKNA 4WJG2 3ZLEA 3CI0J 2WIIC 2KRIA 1NWVA 3WSYA 1MD7A 2V8EA 3GXEA 2W80A 1G4FA 1VVCA 3IU3I 2X2ZA 4N7EA 2EHFA 2XRBA 1OK3A 1FBRA 4B2SA 4MUCA 2JGWA 1UOTP 1OJYA 5FO8C 1H03P 4FXGG 3ERBA 2A55A 3NJAA 4IGDA 1Q3XA 4MSLA 2RLPA 2IZ4A 4F4OC 2MCZA 1ZJKA
chains in the Genus database with same CATH topology
1E8BA 3TVJA 5HYUB 1GHQB 2W81A 1ELVA 2EC3A 5I0QB 3OP8A 1TPMA 2IZ3A 3T5OA 2RKYA 3ZD1A 1QGBA 2XWJI 2RLQA 2XRDA 1QUBA 1HCCA 2ERJA 4PZ5A 1E5GA 2CG7A 4JHSA 1SS2A 4ONTD 2CG6A 2LOJA 3IX0A 1OK9A 1H04P 3NFPI 4YNXA 2YRAA 3ZD2A 1LY2A 1H2PP 5HZPB 1OJVA 4AYMA 2JRAA 3RJ3D 4AYDA 1OK1A 3SW0X 1CKLA 1OK2A 1HFHA 3OXUD 1OJWA 1O9AA 1TPNA 2KMSA 1GPZA 2JGXA 3CALA 3KZJA 1E88A 1MD8A 1G4GA 5HYPA 3GOVA 4CSYA 2B5ID 4DJZA 4AYEA 3INBC 1PPQA 2MCYA 4A5WB 3O8EB 2CKUA 1VVDA 1HFIA 2QY0A 1U5MA 5HYTB 2O39C 2XQWC 4LOTA 3KXVA 1C1ZA 4KKDA 4LOSA 1TPGA 4J38B 1Z92B 3M7PA 3ZRZA 4B2RA 3OEDC 2BZMA 1H2QP 5JPMG 2XWBF 2YBYA 4ZH1D 3MQLA 1SRZA 3EJHA 2RL0A 2RKZA 4C16A 1QO6A 3L89M 4K12A 1GKGA 2G7IA 2UWNA 3R62A 4AYIA 1GKNA 4WJG2 2WIIC 2KRIA 1NWVA 1MD7A 2V8EA 3GXEA 2W80A 1G4FA 1VVCA 3IU3I 2EHFA 2XRBA 1OK3A 1FBRA 4B2SA 4MUCA 2JGWA 1UOTP 1OJYA 5FO8C 1H03P 4FXGG 3ERBA 2A55A 4IGDA 1Q3XA 2RLPA 2IZ4A 4F4OC 2MCZA 1ZJKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E8B A;  3TVJ A;  5HYU B;  1GHQ B;  2W81 A;  1ELV A;  2EC3 A;  5I0Q B;  3OP8 A;  1TPM A;  2IZ3 A;  3T5O A;  2RKY A;  3ZD1 A;  1QGB A;  2XWJ I;  2RLQ A;  2XRD A;  1QUB A;  1HCC A;  2ERJ A;  4PZ5 A;  1E5G A;  2CG7 A;  4JHS A;  1SS2 A;  4ONT D;  2CG6 A;  2LOJ A;  3IX0 A;  1OK9 A;  1H04 P;  3NFP I;  4YNX A;  2YRA A;  3ZD2 A;  1LY2 A;  1H2P P;  5HZP B;  1OJV A;  4AYM A;  2JRA A;  3RJ3 D;  4AYD A;  1OK1 A;  3SW0 X;  1CKL A;  1OK2 A;  1HFH A;  3OXU D;  1OJW A;  1O9A A;  1TPN A;  2KMS A;  1GPZ A;  2JGX A;  3CAL A;  3KZJ A;  1E88 A;  1MD8 A;  1G4G A;  5HYP A;  3GOV A;  4CSY A;  2B5I D;  4DJZ A;  4AYE A;  3INB C;  1PPQ A;  2MCY A;  4A5W B;  3O8E B;  2CKU A;  1VVD A;  1HFI A;  2QY0 A;  1U5M A;  5HYT B;  2O39 C;  2XQW C;  4LOT A;  3KXV A;  1C1Z A;  4KKD A;  4LOS A;  1TPG A;  4J38 B;  1Z92 B;  3M7P A;  3ZRZ A;  4B2R A;  3OED C;  2BZM A;  1H2Q P;  5JPM G;  2XWB F;  2YBY A;  4ZH1 D;  3MQL A;  1SRZ A;  3EJH A;  2RL0 A;  2RKZ A;  4C16 A;  1QO6 A;  3L89 M;  4K12 A;  1GKG A;  2G7I A;  2UWN A;  3R62 A;  4AYI A;  1GKN A;  4WJG 2;  2WII C;  2KRI A;  1NWV A;  1MD7 A;  2V8E A;  3GXE A;  2W80 A;  1G4F A;  1VVC A;  3IU3 I;  2EHF A;  2XRB A;  1OK3 A;  1FBR A;  4B2S A;  4MUC A;  2JGW A;  1UOT P;  1OJY A;  5FO8 C;  1H03 P;  4FXG G;  3ERB A;  2A55 A;  4IGD A;  1Q3X A;  2RLP A;  2IZ4 A;  4F4O C;  2MCZ A;  1ZJK A; 
#chains in the Genus database with same CATH topology
 1E8B A;  3TVJ A;  5HYU B;  3VWO A;  1GHQ B;  2W81 A;  1ELV A;  2EC3 A;  5I0Q B;  2ZYC A;  3OP8 A;  1TPM A;  2IZ3 A;  3T5O A;  2RKY A;  3FGT A;  3ZD1 A;  2Y8R A;  1QGB A;  2XWJ I;  2RLQ A;  2XRD A;  1QUB A;  1HCC A;  2ERJ A;  2Y8S A;  4PZ5 A;  2CG7 A;  4JHS A;  1E5G A;  1SS2 A;  4ONT D;  2CG6 A;  2LOJ A;  3IX0 A;  1OK9 A;  3F6K A;  1H04 P;  3NFP I;  4YNX A;  2YRA A;  3ZD2 A;  1LY2 A;  1H2P P;  5HZP B;  1OJV A;  4AYM A;  3ZLD A;  2JRA A;  3RJ3 D;  4AYD A;  1OK1 A;  3SW0 X;  1CKL A;  1OK2 A;  1HFH A;  3OXU D;  1OJW A;  1O9A A;  1TPN A;  2KMS A;  1GPZ A;  2JGX A;  3CAL A;  3KZJ A;  5DN5 A;  1E88 A;  1MD8 A;  1G4G A;  5HYP A;  3GOV A;  4CSY A;  2B5I D;  5DN4 A;  4DJZ A;  4AYE A;  4C16 A;  2I2L A;  3INB C;  1PPQ A;  2MCY A;  4A5W B;  3O8E B;  2CKU A;  1VVD A;  1HFI A;  2QY0 A;  1U5M A;  5HYT B;  2O39 C;  2XQW C;  4LOT A;  3WSX A;  3KXV A;  1C1Z A;  4KKD A;  4LOS A;  1TPG A;  2Y8T A;  4J38 B;  1Z92 B;  4APL A;  3M7P A;  3ZRZ A;  4B2R A;  3OED C;  2BZM A;  1H2Q P;  5JPM G;  2XWB F;  2YBY A;  4ZH1 D;  4BWC A;  3MQL A;  4YIZ A;  1SRZ A;  3EJH A;  2RL0 A;  2RKZ A;  3K3T A;  1QO6 A;  1RLH A;  3L89 M;  3FGR A;  2G7I A;  2UWN A;  3R62 A;  4K12 A;  4PO7 A;  4AYI A;  1GKG A;  1GKN A;  4WJG 2;  3ZLE A;  3CI0 J;  2WII C;  2KRI A;  1NWV A;  3WSY A;  1MD7 A;  2V8E A;  3GXE A;  2W80 A;  1G4F A;  1VVC A;  3IU3 I;  2X2Z A;  4N7E A;  2EHF A;  2XRB A;  1OK3 A;  1FBR A;  4B2S A;  4MUC A;  2JGW A;  1UOT P;  1OJY A;  5FO8 C;  1H03 P;  4FXG G;  3ERB A;  2A55 A;  3NJA A;  4IGD A;  1Q3X A;  4MSL A;  2RLP A;  2IZ4 A;  4F4O C;  2MCZ A;  1ZJK A; 
#chains in the Genus database with same CATH homology
 1E8B A;  3TVJ A;  5HYU B;  1GHQ B;  2W81 A;  1ELV A;  2EC3 A;  5I0Q B;  3OP8 A;  1TPM A;  2IZ3 A;  3T5O A;  2RKY A;  3ZD1 A;  1QGB A;  2XWJ I;  2RLQ A;  2XRD A;  1QUB A;  1HCC A;  2ERJ A;  4PZ5 A;  1E5G A;  2CG7 A;  4JHS A;  1SS2 A;  4ONT D;  2CG6 A;  2LOJ A;  3IX0 A;  1OK9 A;  1H04 P;  3NFP I;  4YNX A;  2YRA A;  3ZD2 A;  1LY2 A;  1H2P P;  5HZP B;  1OJV A;  4AYM A;  2JRA A;  3RJ3 D;  4AYD A;  1OK1 A;  3SW0 X;  1CKL A;  1OK2 A;  1HFH A;  3OXU D;  1OJW A;  1O9A A;  1TPN A;  2KMS A;  1GPZ A;  2JGX A;  3CAL A;  3KZJ A;  1E88 A;  1MD8 A;  1G4G A;  5HYP A;  3GOV A;  4CSY A;  2B5I D;  4DJZ A;  4AYE A;  3INB C;  1PPQ A;  2MCY A;  4A5W B;  3O8E B;  2CKU A;  1VVD A;  1HFI A;  2QY0 A;  1U5M A;  5HYT B;  2O39 C;  2XQW C;  4LOT A;  3KXV A;  1C1Z A;  4KKD A;  4LOS A;  1TPG A;  4J38 B;  1Z92 B;  3M7P A;  3ZRZ A;  4B2R A;  3OED C;  2BZM A;  1H2Q P;  5JPM G;  2XWB F;  2YBY A;  4ZH1 D;  3MQL A;  1SRZ A;  3EJH A;  2RL0 A;  2RKZ A;  4C16 A;  1QO6 A;  3L89 M;  4K12 A;  1GKG A;  2G7I A;  2UWN A;  3R62 A;  4AYI A;  1GKN A;  4WJG 2;  2WII C;  2KRI A;  1NWV A;  1MD7 A;  2V8E A;  3GXE A;  2W80 A;  1G4F A;  1VVC A;  3IU3 I;  2EHF A;  2XRB A;  1OK3 A;  1FBR A;  4B2S A;  4MUC A;  2JGW A;  1UOT P;  1OJY A;  5FO8 C;  1H03 P;  4FXG G;  3ERB A;  2A55 A;  4IGD A;  1Q3X A;  2RLP A;  2IZ4 A;  4F4O C;  2MCZ A;  1ZJK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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