3WSYA

Sorla vps10p domain in complex with its own propeptide fragment
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
668
structure length
662
Chain Sequence
QPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLGNRSEAVIAQFYHSPADNKRYIFADAYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDKPNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYYIADASEDQVFVCVSHSNNRTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYYTWGDHGGIITAIAQGMETNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIFGSNKENVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGPPVPCPSTYRRTRGYRKISGDTCSGGDVEARLEGELVPCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Sortilin-related receptor
publication title Structural basis for amyloidogenic peptide recognition by sorLA
doi rcsb
source organism Homo sapiens
molecule tags Protein binding
total genus 144
structure length 662
sequence length 668
ec nomenclature
pdb deposition date 2014-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF15901 Sortilin_C Sortilin, neurotensin receptor 3, C-terminal
A PF15902 Sortilin-Vps10 Sortilin, neurotensin receptor 3,
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.90 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 3wsyA03
3F6KA 4MSLA 4PO7A 3WSXA 4N7EA 3WSYA
chains in the Genus database with same CATH superfamily
1H03P 1HFIA 4B2RA 1O9AA 2IZ4A 1UOTP 3OEDC 3ERBA 3KXVA 5JPMG 3TVJA 3WSYA 2Y8SA 2V8EA 3GXEA 1GKGA 1H2PP 2O39C 2MCYA 1H2QP 3CI0J 2XWJI 2WIIC 1HFHA 1QO6A 2RLQA 2JGXA 3ZLEA 1OJWA 5DN5A 3IX0A 1GPZA 1Q3XA 4LOSA 1C1ZA 3OP8A 4B2SA 2X2ZA 1E8BA 4YIZA 1FBRA 1OK2A 4AYDA 2B5ID 3CALA 4BWCA 1TPGA 2JGWA 2RKYA 3FGRA 5DN4A 3FGTA 5FO8C 3GOVA 2BZMA 3O8EB 1G4GA 1CKLA 2UWNA 5HZPB 2Y8TA 3VWOA 4PZ5A 1MD7A 3WSXA 2CKUA 2ZYCA 4APLA 1PPQA 2Y8RA 4F4OC 4JHSA 2RKZA 5HYPA 2ERJA 2XQWC 1TPMA 1OK1A 2CG6A 3SW0X 3M7PA 3KZJA 4WJG2 4YNXA 5HYUB 1E5GA 2EHFA 2MCZA 4A5WB 4AYIA 4ZH1D 2YRAA 2KMSA 1QUBA 4AYEA 1VVDA 3IU3I 1H04P 2A55A 3ZLDA 1MD8A 2I2LA 1VVCA 2KRIA 5I0QB 4CSYA 4FXGG 4AYMA 3OXUD 4N7EA 2EC3A 1G4FA 1ELVA 3ZRZA 2QY0A 1OJYA 4C16A 2CG7A 3K3TA 1E88A 4K12A 1NWVA 2RLPA 5HYTB 2XWBF 3EJHA 1GHQB 2XRBA 4MSLA 1OJVA 2RL0A 1GKNA 3NJAA 1Z92B 3MQLA 2W80A 4LOTA 1OK3A 3RJ3D 3NFPI 2XRDA 2LOJA 3ZD2A 1ZJKA 1U5MA 2G7IA 1SRZA 4ONTD 3ZD1A 4J38B 1QGBA 3F6KA 1LY2A 3L89M 1TPNA 4PO7A 3INBC 2YBYA 1HCCA 1SS2A 3T5OA 1OK9A 3R62A 4MUCA 4IGDA 2W81A 2IZ3A 1RLHA 4KKDA 2JRAA 4DJZA
chains in the Genus database with same CATH topology
4YIZA 4MSLA 4BWCA 3NJAA 3WSYA 2Y8SA 3FGRA 3FGTA 3ZLDA 2Y8TA 2I2LA 3F6KA 4PO7A 3WSXA 4N7EA 3ZLEA 4APLA 2Y8RA 2X2ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F6K A;  4MSL A;  4PO7 A;  3WSX A;  4N7E A;  3WSY A; 
#chains in the Genus database with same CATH topology
 1H03 P;  1HFI A;  4B2R A;  1O9A A;  2IZ4 A;  1UOT P;  3OED C;  3ERB A;  3KXV A;  5JPM G;  3TVJ A;  3WSY A;  2Y8S A;  2V8E A;  3GXE A;  1GKG A;  1H2P P;  2O39 C;  2MCY A;  1H2Q P;  3CI0 J;  2XWJ I;  2WII C;  1HFH A;  1QO6 A;  2RLQ A;  2JGX A;  3ZLE A;  1OJW A;  5DN5 A;  3IX0 A;  1GPZ A;  1Q3X A;  4LOS A;  1C1Z A;  3OP8 A;  4B2S A;  2X2Z A;  1E8B A;  4YIZ A;  1FBR A;  1OK2 A;  4AYD A;  2B5I D;  3CAL A;  4BWC A;  1TPG A;  2JGW A;  2RKY A;  3FGR A;  5DN4 A;  3FGT A;  5FO8 C;  3GOV A;  2BZM A;  3O8E B;  1G4G A;  1CKL A;  2UWN A;  5HZP B;  2Y8T A;  3VWO A;  4PZ5 A;  1MD7 A;  3WSX A;  2CKU A;  2ZYC A;  4APL A;  1PPQ A;  2Y8R A;  4F4O C;  4JHS A;  2RKZ A;  5HYP A;  2ERJ A;  2XQW C;  1TPM A;  1OK1 A;  2CG6 A;  3SW0 X;  3M7P A;  3KZJ A;  4WJG 2;  4YNX A;  5HYU B;  1E5G A;  2EHF A;  2MCZ A;  4A5W B;  4AYI A;  4ZH1 D;  2YRA A;  2KMS A;  1QUB A;  4AYE A;  1VVD A;  3IU3 I;  1H04 P;  2A55 A;  3ZLD A;  1MD8 A;  2I2L A;  1VVC A;  2KRI A;  5I0Q B;  4CSY A;  4FXG G;  4AYM A;  3OXU D;  4N7E A;  2EC3 A;  1G4F A;  1ELV A;  3ZRZ A;  2QY0 A;  1OJY A;  4C16 A;  2CG7 A;  3K3T A;  1E88 A;  4K12 A;  1NWV A;  2RLP A;  5HYT B;  2XWB F;  3EJH A;  1GHQ B;  2XRB A;  4MSL A;  1OJV A;  2RL0 A;  1GKN A;  3NJA A;  1Z92 B;  3MQL A;  2W80 A;  4LOT A;  1OK3 A;  3RJ3 D;  3NFP I;  2XRD A;  2LOJ A;  3ZD2 A;  1ZJK A;  1U5M A;  2G7I A;  1SRZ A;  4ONT D;  3ZD1 A;  4J38 B;  1QGB A;  3F6K A;  1LY2 A;  3L89 M;  1TPN A;  4PO7 A;  3INB C;  2YBY A;  1HCC A;  1SS2 A;  3T5O A;  1OK9 A;  3R62 A;  4MUC A;  4IGD A;  2W81 A;  2IZ3 A;  1RLH A;  4KKD A;  2JRA A;  4DJZ A; 
#chains in the Genus database with same CATH homology
 4YIZ A;  4MSL A;  4BWC A;  3NJA A;  3WSY A;  2Y8S A;  3FGR A;  3FGT A;  3ZLD A;  2Y8T A;  2I2L A;  3F6K A;  4PO7 A;  3WSX A;  4N7E A;  3ZLE A;  4APL A;  2Y8R A;  2X2Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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