1GKNA

Structure determination and rational mutagenesis reveal binding surface of immune adherence receptor, cr1 (cd35)
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
128
structure length
128
Chain Sequence
EAEAHCQAPDHFLFAKLKTQTTASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRITYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
pubmed doi rcsb
molecule tags Complement
source organism Homo sapiens
molecule keywords COMPLEMENT RECEPTOR TYPE 1
total genus 14
structure length 128
sequence length 128
ec nomenclature
pdb deposition date 2001-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA02
5I0QB 1PPQA 3ZRZA 1OK3A 4PZ5A 3IU3I 1G4GA 1O9AA 1H04P 3O8EB 4LOSA 2RLQA 2XWBF 2MCYA 1SRZA 4LOTA 2KRIA 1FBRA 1E88A 5HYTB 1C1ZA 3CALA 2KMSA 3INBC 1ELVA 4DJZA 5HZPB 5JPMG 1NWVA 4AYMA 4F4OC 1UOTP 1TPNA 3L89M 2RLPA 5HYUB 3MQLA 4YNXA 2O39C 2RKZA 1VVDA 3ZD1A 2B5ID 1GHQB 2W80A 1QGBA 4AYDA 4FXGG 4MUCA 3ZD2A 1OK1A 1TPGA 2XRBA 4C16A 1E8BA 1G4FA 4ZH1D 4B2SA 3OXUD 1OK2A 5HYPA 2IZ4A 2UWNA 2CG6A 2LOJA 1E5GA 3R62A 4KKDA 1HFHA 3TVJA 4CSYA 1H2PP 1OJYA 1CKLA 3NFPI 1MD8A 4ONTD 2JGXA 1Z92B 2EHFA 2RL0A 2WIIC 3EJHA 4A5WB 1QO6A 1SS2A 1GKGA 1U5MA 2EC3A 1ZJKA 1H2QP 3GOVA 4JHSA 3RJ3D 1Q3XA 4AYIA 2W81A 4J38B 2XWJI 2RKYA 2V8EA 1OK9A 2A55A 1QUBA 4K12A 1OJVA 1GPZA 2IZ3A 1HFIA 1OJWA 2JGWA 3ERBA 4IGDA 3KZJA 1LY2A 3M7PA 3OEDC 2CG7A 3IX0A 1TPMA 3T5OA 2ERJA 1HCCA 1H03P 1VVCA 2QY0A 3KXVA 2YBYA 2BZMA 3OP8A 4AYEA 1MD7A 2MCZA 4WJG2 1GKNA 4B2RA 2JRAA 2XQWC 2CKUA 5FO8C 3SW0X 3GXEA 2G7IA 2XRDA 2YRAA
chains in the Genus database with same CATH superfamily
5I0QB 1PPQA 3ZRZA 1OK3A 4PZ5A 3IU3I 2Y8TA 1G4GA 3NJAA 1O9AA 1H04P 3O8EB 4LOSA 2RLQA 2XWBF 2MCYA 3WSXA 1SRZA 4LOTA 2KRIA 1FBRA 3WSYA 1E88A 5HYTB 3CI0J 1C1ZA 3CALA 2KMSA 3INBC 1ELVA 4N7EA 4DJZA 5HZPB 5JPMG 1NWVA 4AYMA 4F4OC 1UOTP 1TPNA 3FGTA 3L89M 2RLPA 5HYUB 3MQLA 3K3TA 4YNXA 2O39C 2RKZA 1VVDA 3ZD1A 2B5ID 1GHQB 2W80A 3ZLDA 2ZYCA 1QGBA 3ZLEA 4AYDA 5DN4A 4FXGG 4MUCA 3ZD2A 1OK1A 1TPGA 2XRBA 4C16A 1E8BA 4PO7A 4ZH1D 1G4FA 4B2SA 3OXUD 1OK2A 5HYPA 2IZ4A 2UWNA 2CG6A 2LOJA 1E5GA 3R62A 4KKDA 1HFHA 3TVJA 4CSYA 1H2PP 1OJYA 1CKLA 3NFPI 4YIZA 1MD8A 4ONTD 2JGXA 1Z92B 2EHFA 2RL0A 2WIIC 2Y8RA 3EJHA 4A5WB 1QO6A 2I2LA 1SS2A 3F6KA 1GKGA 1U5MA 5DN5A 2EC3A 1ZJKA 3FGRA 3VWOA 1H2QP 3GOVA 4JHSA 3RJ3D 1Q3XA 4AYIA 2W81A 4J38B 2XWJI 4MSLA 4APLA 4BWCA 2RKYA 2V8EA 1OK9A 2A55A 1QUBA 4K12A 1OJVA 1GPZA 2IZ3A 1HFIA 1OJWA 2JGWA 3ERBA 4IGDA 3KZJA 1LY2A 3M7PA 1RLHA 3OEDC 2CG7A 3IX0A 1TPMA 3T5OA 2ERJA 1HCCA 2Y8SA 1H03P 1VVCA 2QY0A 3KXVA 2YBYA 2BZMA 3OP8A 4AYEA 1MD7A 2MCZA 4WJG2 1GKNA 2X2ZA 4B2RA 2JRAA 2XQWC 2CKUA 5FO8C 3SW0X 3GXEA 2G7IA 2XRDA 2YRAA
chains in the Genus database with same CATH topology
5I0QB 1PPQA 3ZRZA 1OK3A 4PZ5A 3IU3I 1G4GA 1O9AA 1H04P 3O8EB 4LOSA 2RLQA 2XWBF 2MCYA 1SRZA 4LOTA 2KRIA 1FBRA 1E88A 5HYTB 1C1ZA 3CALA 2KMSA 3INBC 1ELVA 4DJZA 5HZPB 5JPMG 1NWVA 4AYMA 4F4OC 1UOTP 1TPNA 3L89M 2RLPA 5HYUB 3MQLA 4YNXA 2O39C 2RKZA 1VVDA 3ZD1A 2B5ID 1GHQB 2W80A 1QGBA 4AYDA 4FXGG 4MUCA 3ZD2A 1OK1A 1TPGA 2XRBA 4C16A 1E8BA 1G4FA 4ZH1D 4B2SA 3OXUD 1OK2A 5HYPA 2IZ4A 2UWNA 2CG6A 2LOJA 1E5GA 3R62A 4KKDA 1HFHA 3TVJA 4CSYA 1H2PP 1OJYA 1CKLA 3NFPI 1MD8A 4ONTD 2JGXA 1Z92B 2EHFA 2RL0A 2WIIC 3EJHA 4A5WB 1QO6A 1SS2A 1GKGA 1U5MA 2EC3A 1ZJKA 1H2QP 3GOVA 4JHSA 3RJ3D 1Q3XA 4AYIA 2W81A 4J38B 2XWJI 2RKYA 2V8EA 1OK9A 2A55A 1QUBA 4K12A 1OJVA 1GPZA 2IZ3A 1HFIA 1OJWA 2JGWA 3ERBA 4IGDA 3KZJA 1LY2A 3M7PA 3OEDC 2CG7A 3IX0A 1TPMA 3T5OA 2ERJA 1HCCA 1H03P 1VVCA 2QY0A 3KXVA 2YBYA 2BZMA 3OP8A 4AYEA 1MD7A 2MCZA 4WJG2 1GKNA 4B2RA 2JRAA 2XQWC 2CKUA 5FO8C 3SW0X 3GXEA 2G7IA 2XRDA 2YRAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I0Q B;  1PPQ A;  3ZRZ A;  1OK3 A;  4PZ5 A;  3IU3 I;  1G4G A;  1O9A A;  1H04 P;  3O8E B;  4LOS A;  2RLQ A;  2XWB F;  2MCY A;  1SRZ A;  4LOT A;  2KRI A;  1FBR A;  1E88 A;  5HYT B;  1C1Z A;  3CAL A;  2KMS A;  3INB C;  1ELV A;  4DJZ A;  5HZP B;  5JPM G;  1NWV A;  4AYM A;  4F4O C;  1UOT P;  1TPN A;  3L89 M;  2RLP A;  5HYU B;  3MQL A;  4YNX A;  2O39 C;  2RKZ A;  1VVD A;  3ZD1 A;  2B5I D;  1GHQ B;  2W80 A;  1QGB A;  4AYD A;  4FXG G;  4MUC A;  3ZD2 A;  1OK1 A;  1TPG A;  2XRB A;  4C16 A;  1E8B A;  1G4F A;  4ZH1 D;  4B2S A;  3OXU D;  1OK2 A;  5HYP A;  2IZ4 A;  2UWN A;  2CG6 A;  2LOJ A;  1E5G A;  3R62 A;  4KKD A;  1HFH A;  3TVJ A;  4CSY A;  1H2P P;  1OJY A;  1CKL A;  3NFP I;  1MD8 A;  4ONT D;  2JGX A;  1Z92 B;  2EHF A;  2RL0 A;  2WII C;  3EJH A;  4A5W B;  1QO6 A;  1SS2 A;  1GKG A;  1U5M A;  2EC3 A;  1ZJK A;  1H2Q P;  3GOV A;  4JHS A;  3RJ3 D;  1Q3X A;  4AYI A;  2W81 A;  4J38 B;  2XWJ I;  2RKY A;  2V8E A;  1OK9 A;  2A55 A;  1QUB A;  4K12 A;  1OJV A;  1GPZ A;  2IZ3 A;  1HFI A;  1OJW A;  2JGW A;  3ERB A;  4IGD A;  3KZJ A;  1LY2 A;  3M7P A;  3OED C;  2CG7 A;  3IX0 A;  1TPM A;  3T5O A;  2ERJ A;  1HCC A;  1H03 P;  1VVC A;  2QY0 A;  3KXV A;  2YBY A;  2BZM A;  3OP8 A;  4AYE A;  1MD7 A;  2MCZ A;  4WJG 2;  1GKN A;  4B2R A;  2JRA A;  2XQW C;  2CKU A;  5FO8 C;  3SW0 X;  3GXE A;  2G7I A;  2XRD A;  2YRA A; 
#chains in the Genus database with same CATH topology
 5I0Q B;  1PPQ A;  3ZRZ A;  1OK3 A;  4PZ5 A;  3IU3 I;  2Y8T A;  1G4G A;  3NJA A;  1O9A A;  1H04 P;  3O8E B;  4LOS A;  2RLQ A;  2XWB F;  2MCY A;  3WSX A;  1SRZ A;  4LOT A;  2KRI A;  1FBR A;  3WSY A;  1E88 A;  5HYT B;  3CI0 J;  1C1Z A;  3CAL A;  2KMS A;  3INB C;  1ELV A;  4N7E A;  4DJZ A;  5HZP B;  5JPM G;  1NWV A;  4AYM A;  4F4O C;  1UOT P;  1TPN A;  3FGT A;  3L89 M;  2RLP A;  5HYU B;  3MQL A;  3K3T A;  4YNX A;  2O39 C;  2RKZ A;  1VVD A;  3ZD1 A;  2B5I D;  1GHQ B;  2W80 A;  3ZLD A;  2ZYC A;  1QGB A;  3ZLE A;  4AYD A;  5DN4 A;  4FXG G;  4MUC A;  3ZD2 A;  1OK1 A;  1TPG A;  2XRB A;  4C16 A;  1E8B A;  4PO7 A;  4ZH1 D;  1G4F A;  4B2S A;  3OXU D;  1OK2 A;  5HYP A;  2IZ4 A;  2UWN A;  2CG6 A;  2LOJ A;  1E5G A;  3R62 A;  4KKD A;  1HFH A;  3TVJ A;  4CSY A;  1H2P P;  1OJY A;  1CKL A;  3NFP I;  4YIZ A;  1MD8 A;  4ONT D;  2JGX A;  1Z92 B;  2EHF A;  2RL0 A;  2WII C;  2Y8R A;  3EJH A;  4A5W B;  1QO6 A;  2I2L A;  1SS2 A;  3F6K A;  1GKG A;  1U5M A;  5DN5 A;  2EC3 A;  1ZJK A;  3FGR A;  3VWO A;  1H2Q P;  3GOV A;  4JHS A;  3RJ3 D;  1Q3X A;  4AYI A;  2W81 A;  4J38 B;  2XWJ I;  4MSL A;  4APL A;  4BWC A;  2RKY A;  2V8E A;  1OK9 A;  2A55 A;  1QUB A;  4K12 A;  1OJV A;  1GPZ A;  2IZ3 A;  1HFI A;  1OJW A;  2JGW A;  3ERB A;  4IGD A;  3KZJ A;  1LY2 A;  3M7P A;  1RLH A;  3OED C;  2CG7 A;  3IX0 A;  1TPM A;  3T5O A;  2ERJ A;  1HCC A;  2Y8S A;  1H03 P;  1VVC A;  2QY0 A;  3KXV A;  2YBY A;  2BZM A;  3OP8 A;  4AYE A;  1MD7 A;  2MCZ A;  4WJG 2;  1GKN A;  2X2Z A;  4B2R A;  2JRA A;  2XQW C;  2CKU A;  5FO8 C;  3SW0 X;  3GXE A;  2G7I A;  2XRD A;  2YRA A; 
#chains in the Genus database with same CATH homology
 5I0Q B;  1PPQ A;  3ZRZ A;  1OK3 A;  4PZ5 A;  3IU3 I;  1G4G A;  1O9A A;  1H04 P;  3O8E B;  4LOS A;  2RLQ A;  2XWB F;  2MCY A;  1SRZ A;  4LOT A;  2KRI A;  1FBR A;  1E88 A;  5HYT B;  1C1Z A;  3CAL A;  2KMS A;  3INB C;  1ELV A;  4DJZ A;  5HZP B;  5JPM G;  1NWV A;  4AYM A;  4F4O C;  1UOT P;  1TPN A;  3L89 M;  2RLP A;  5HYU B;  3MQL A;  4YNX A;  2O39 C;  2RKZ A;  1VVD A;  3ZD1 A;  2B5I D;  1GHQ B;  2W80 A;  1QGB A;  4AYD A;  4FXG G;  4MUC A;  3ZD2 A;  1OK1 A;  1TPG A;  2XRB A;  4C16 A;  1E8B A;  1G4F A;  4ZH1 D;  4B2S A;  3OXU D;  1OK2 A;  5HYP A;  2IZ4 A;  2UWN A;  2CG6 A;  2LOJ A;  1E5G A;  3R62 A;  4KKD A;  1HFH A;  3TVJ A;  4CSY A;  1H2P P;  1OJY A;  1CKL A;  3NFP I;  1MD8 A;  4ONT D;  2JGX A;  1Z92 B;  2EHF A;  2RL0 A;  2WII C;  3EJH A;  4A5W B;  1QO6 A;  1SS2 A;  1GKG A;  1U5M A;  2EC3 A;  1ZJK A;  1H2Q P;  3GOV A;  4JHS A;  3RJ3 D;  1Q3X A;  4AYI A;  2W81 A;  4J38 B;  2XWJ I;  2RKY A;  2V8E A;  1OK9 A;  2A55 A;  1QUB A;  4K12 A;  1OJV A;  1GPZ A;  2IZ3 A;  1HFI A;  1OJW A;  2JGW A;  3ERB A;  4IGD A;  3KZJ A;  1LY2 A;  3M7P A;  3OED C;  2CG7 A;  3IX0 A;  1TPM A;  3T5O A;  2ERJ A;  1HCC A;  1H03 P;  1VVC A;  2QY0 A;  3KXV A;  2YBY A;  2BZM A;  3OP8 A;  4AYE A;  1MD7 A;  2MCZ A;  4WJG 2;  1GKN A;  4B2R A;  2JRA A;  2XQW C;  2CKU A;  5FO8 C;  3SW0 X;  3GXE A;  2G7I A;  2XRD A;  2YRA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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