1GK3A

Histidine ammonia-lyase (hal) mutant d145a from pseudomonas putida
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
509
structure length
509
Chain Sequence
TELTLKPGTLTLAQLRAIHAAPVRLQLDASAAPAIDASVACVEQIIAEDRTAYGINTGFGLLASTRIASHDLENLQRSLVLSHAAGIGAPLDDDLVRLIMVLKINSLSRGFSGIRRKVIDALIALVNAEVYPHIPLKGSVGASGALAPLAHMSLVLLGEGKARYKGQWLSATEALAVAGLEPLTLAAKEGLALLNGTQASTAYALRGLFYAEDLYAAAIACGGLSVEAVLGSRSPFDARIHEARGQRGQIDTAACFRDLLGDSSEVSLSHKNADKVQDPYSLRCQPQVMGACLTQLRQAAEVLGIEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNLALAIAEIGSLSERRISLMMDKHMSQLPPFLVENGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGVLAIEWLGACQGLDLRKGLKTSAKLEKARQALRSEVAHYDRDRFFAPDIEKAVELLAKGSLTGLLPAGVLPSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Autocatalytic Peptide Cyclization During Chain Folding of Histidine Ammonia-Lyase.
pubmed doi rcsb
molecule tags Lyase
source organism Pseudomonas putida
molecule keywords HISTIDINE AMMONIA-LYASE
total genus 192
structure length 509
sequence length 509
ec nomenclature ec 4.3.1.3: Histidine ammonia-lyase.
pdb deposition date 2001-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1gk3A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1gk3A02
1DOFA 1JSWA 1RE5A 1TJVA 3R6QA 2YIIA 1YFEA 3UNVA 2PTSA 4C5UA 3KDYA 1U15A 4EEIA 1YFMA 5EYTA 3TV2A 4APAA 1K7WA 1T6JA 3QBPA 1FUQA 1Q5NA 5D6BA 2FUSA 2J91A 1TJWA 2O7BA 1HY1A 1GKMA 2E9FA 2PFMA 2VD6A 3OCEA 1FUPA 4NLEA 2OHYA 2O7EA 2O7FA 2RJSA 1FUOA 5F92A 2X75A 4HGVA 1DCNA 1GK2A 1U16A 1YISA 2O78A 4FFXA 1VDKA 3GTDA 4NSLA 3R6YA 5EYVA 4FLCA 1C3CA 2NYNA 2O6YA 3GZHA 5F91A 1J3UA 2RJRA 4V2RA 4BABA 2NYFA 1T6PA 4C5SA 2PTQA 1AUWA 3RD8A 3NO9A 1XWOA 3R6VA 2O7DA 3KDZA 4V2QA 4BAAA 1Y2MA 1HY0A 4C5RA 1I0AA 2QVEA 4ADMA 1K62A 4APBA 4ADLA 3NZ4A 1KQ7A 2QGAB 1GKJA 3CZOA 2HVGA 3C8TA 1TJUA 1W27A 3BHGA 4C6GA 4CQ5A 1TJ7A 3E04A 3RRPA 4MX2A 1FURA 1B8FA 2PTRA 5HW2A 1C3UA 1GK3A 1EB4A 4EFCA 3OCFA
chains in the Genus database with same CATH superfamily
1DOFA 1JSWA 1RE5A 1TJVA 2VSFA 2YIIA 1YFEA 3R6QA 3UNVA 2PTSA 4A15A 4C5UA 3KDYA 1U15A 4EEIA 1YFMA 5EYTA 3TV2A 1XMDA 4APAA 1K7WA 4WNLA 1T6JA 3QBPA 1FUQA 1Q5NA 5D6BA 2FUSA 2J91A 1TJWA 2O7BA 1HY1A 1GKMA 1XMCA 1XL8A 2E9FA 2PFMA 2VD6A 3OCEA 1FUPA 4NLEA 2OHYA 2O7EA 2O7FA 2RJSA 1FUOA 5F92A 2X75A 3CRVA 4HGVA 1DCNA 1GK2A 1U16A 1YISA 5H8WA 2O78A 4FFXA 1VDKA 3GTDA 4NSLA 3R6YA 5EYVA 4FLCA 1C3CA 2NYNA 2O6YA 3GZHA 5F91A 1J3UA 2RJRA 4V2RA 4BABA 2NYFA 1T6PA 4C5SA 2PTQA 1AUWA 2FENA 3RD8A 3NO9A 1XWOA 3R6VA 2O7DA 3KDZA 4V2QA 4BAAA 1Y2MA 5M0JA 1HY0A 4C5RA 1I0AA 2QVEA 5M0IA 4ADMA 1K62A 4APBA 4ADLA 3NZ4A 1KQ7A 2QGAB 1GKJA 2VL7A 3CZOA 1XLYA 2HVGA 3C8TA 1TJUA 1W27A 1XL7A 3BHGA 4C6GA 4CQ5A 1TJ7A 3E04A 3RRPA 4MX2A 1FURA 3CRW1 1B8FA 2PTRA 5HW2A 2FELA 1C3UA 1GK3A 1EB4A 4EFCA 3OCFA
chains in the Genus database with same CATH topology
1DOFA 1JSWA 1RE5A 1TJVA 3R6QA 2YIIA 1YFEA 3UNVA 2PTSA 4C5UA 3KDYA 1U15A 4EEIA 1YFMA 5EYTA 3TV2A 4APAA 1K7WA 1T6JA 3QBPA 1FUQA 1Q5NA 5D6BA 2FUSA 2J91A 1TJWA 2O7BA 1HY1A 1GKMA 2E9FA 2PFMA 2VD6A 3OCEA 1FUPA 4NLEA 2OHYA 2O7EA 2O7FA 2RJSA 1FUOA 5F92A 2X75A 4HGVA 1DCNA 1GK2A 1U16A 1YISA 2O78A 4FFXA 1VDKA 3GTDA 4NSLA 3R6YA 5EYVA 4FLCA 1C3CA 2NYNA 2O6YA 3GZHA 5F91A 1J3UA 2RJRA 4V2RA 4BABA 2NYFA 1T6PA 4C5SA 2PTQA 1AUWA 3RD8A 3NO9A 1XWOA 3R6VA 2O7DA 3KDZA 4V2QA 4BAAA 1Y2MA 1HY0A 4C5RA 1I0AA 2QVEA 4ADMA 1K62A 4APBA 4ADLA 3NZ4A 1KQ7A 2QGAB 1GKJA 3CZOA 2HVGA 3C8TA 1TJUA 1W27A 3BHGA 4C6GA 4CQ5A 1TJ7A 3E04A 3RRPA 4MX2A 1FURA 1B8FA 2PTRA 5HW2A 1C3UA 1GK3A 1EB4A 4EFCA 3OCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DOF A;  1JSW A;  1RE5 A;  1TJV A;  3R6Q A;  2YII A;  1YFE A;  3UNV A;  2PTS A;  4C5U A;  3KDY A;  1U15 A;  4EEI A;  1YFM A;  5EYT A;  3TV2 A;  4APA A;  1K7W A;  1T6J A;  3QBP A;  1FUQ A;  1Q5N A;  5D6B A;  2FUS A;  2J91 A;  1TJW A;  2O7B A;  1HY1 A;  1GKM A;  2E9F A;  2PFM A;  2VD6 A;  3OCE A;  1FUP A;  4NLE A;  2OHY A;  2O7E A;  2O7F A;  2RJS A;  1FUO A;  5F92 A;  2X75 A;  4HGV A;  1DCN A;  1GK2 A;  1U16 A;  1YIS A;  2O78 A;  4FFX A;  1VDK A;  3GTD A;  4NSL A;  3R6Y A;  5EYV A;  4FLC A;  1C3C A;  2NYN A;  2O6Y A;  3GZH A;  5F91 A;  1J3U A;  2RJR A;  4V2R A;  4BAB A;  2NYF A;  1T6P A;  4C5S A;  2PTQ A;  1AUW A;  3RD8 A;  3NO9 A;  1XWO A;  3R6V A;  2O7D A;  3KDZ A;  4V2Q A;  4BAA A;  1Y2M A;  1HY0 A;  4C5R A;  1I0A A;  2QVE A;  4ADM A;  1K62 A;  4APB A;  4ADL A;  3NZ4 A;  1KQ7 A;  2QGA B;  1GKJ A;  3CZO A;  2HVG A;  3C8T A;  1TJU A;  1W27 A;  3BHG A;  4C6G A;  4CQ5 A;  1TJ7 A;  3E04 A;  3RRP A;  4MX2 A;  1FUR A;  1B8F A;  2PTR A;  5HW2 A;  1C3U A;  1GK3 A;  1EB4 A;  4EFC A;  3OCF A; 
#chains in the Genus database with same CATH topology
 1DOF A;  1JSW A;  1RE5 A;  1TJV A;  2VSF A;  2YII A;  1YFE A;  3R6Q A;  3UNV A;  2PTS A;  4A15 A;  4C5U A;  3KDY A;  1U15 A;  4EEI A;  1YFM A;  5EYT A;  3TV2 A;  1XMD A;  4APA A;  1K7W A;  4WNL A;  1T6J A;  3QBP A;  1FUQ A;  1Q5N A;  5D6B A;  2FUS A;  2J91 A;  1TJW A;  2O7B A;  1HY1 A;  1GKM A;  1XMC A;  1XL8 A;  2E9F A;  2PFM A;  2VD6 A;  3OCE A;  1FUP A;  4NLE A;  2OHY A;  2O7E A;  2O7F A;  2RJS A;  1FUO A;  5F92 A;  2X75 A;  3CRV A;  4HGV A;  1DCN A;  1GK2 A;  1U16 A;  1YIS A;  5H8W A;  2O78 A;  4FFX A;  1VDK A;  3GTD A;  4NSL A;  3R6Y A;  5EYV A;  4FLC A;  1C3C A;  2NYN A;  2O6Y A;  3GZH A;  5F91 A;  1J3U A;  2RJR A;  4V2R A;  4BAB A;  2NYF A;  1T6P A;  4C5S A;  2PTQ A;  1AUW A;  2FEN A;  3RD8 A;  3NO9 A;  1XWO A;  3R6V A;  2O7D A;  3KDZ A;  4V2Q A;  4BAA A;  1Y2M A;  5M0J A;  1HY0 A;  4C5R A;  1I0A A;  2QVE A;  5M0I A;  4ADM A;  1K62 A;  4APB A;  4ADL A;  3NZ4 A;  1KQ7 A;  2QGA B;  1GKJ A;  2VL7 A;  3CZO A;  1XLY A;  2HVG A;  3C8T A;  1TJU A;  1W27 A;  1XL7 A;  3BHG A;  4C6G A;  4CQ5 A;  1TJ7 A;  3E04 A;  3RRP A;  4MX2 A;  1FUR A;  3CRW 1;  1B8F A;  2PTR A;  5HW2 A;  2FEL A;  1C3U A;  1GK3 A;  1EB4 A;  4EFC A;  3OCF A; 
#chains in the Genus database with same CATH homology
 1DOF A;  1JSW A;  1RE5 A;  1TJV A;  3R6Q A;  2YII A;  1YFE A;  3UNV A;  2PTS A;  4C5U A;  3KDY A;  1U15 A;  4EEI A;  1YFM A;  5EYT A;  3TV2 A;  4APA A;  1K7W A;  1T6J A;  3QBP A;  1FUQ A;  1Q5N A;  5D6B A;  2FUS A;  2J91 A;  1TJW A;  2O7B A;  1HY1 A;  1GKM A;  2E9F A;  2PFM A;  2VD6 A;  3OCE A;  1FUP A;  4NLE A;  2OHY A;  2O7E A;  2O7F A;  2RJS A;  1FUO A;  5F92 A;  2X75 A;  4HGV A;  1DCN A;  1GK2 A;  1U16 A;  1YIS A;  2O78 A;  4FFX A;  1VDK A;  3GTD A;  4NSL A;  3R6Y A;  5EYV A;  4FLC A;  1C3C A;  2NYN A;  2O6Y A;  3GZH A;  5F91 A;  1J3U A;  2RJR A;  4V2R A;  4BAB A;  2NYF A;  1T6P A;  4C5S A;  2PTQ A;  1AUW A;  3RD8 A;  3NO9 A;  1XWO A;  3R6V A;  2O7D A;  3KDZ A;  4V2Q A;  4BAA A;  1Y2M A;  1HY0 A;  4C5R A;  1I0A A;  2QVE A;  4ADM A;  1K62 A;  4APB A;  4ADL A;  3NZ4 A;  1KQ7 A;  2QGA B;  1GKJ A;  3CZO A;  2HVG A;  3C8T A;  1TJU A;  1W27 A;  3BHG A;  4C6G A;  4CQ5 A;  1TJ7 A;  3E04 A;  3RRP A;  4MX2 A;  1FUR A;  1B8F A;  2PTR A;  5HW2 A;  1C3U A;  1GK3 A;  1EB4 A;  4EFC A;  3OCF A; 
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similar chains in the Genus database (?% sequence similarity)
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