1GKNA

Structure determination and rational mutagenesis reveal binding surface of immune adherence receptor, cr1 (cd35)
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
128
structure length
128
Chain Sequence
EAEAHCQAPDHFLFAKLKTQTTASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRITYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Complement
source organism Homo sapiens
publication title Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
pubmed doi rcsb
molecule keywords COMPLEMENT RECEPTOR TYPE 1
total genus 14
structure length 128
sequence length 128
ec nomenclature
pdb deposition date 2001-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA02
3ERBA 1SRZA 1E8BA 3CALA 1H04P 1QO6A 2RKZA 1MD7A 4AYDA 2JGXA 2CKUA 4LOTA 5JPMG 1HFHA 4JHSA 1Z92B 4AYMA 3IX0A 1SS2A 3RJ3D 3L89M 4IGDA 4YNXA 5I0QB 2A55A 1OJVA 4B2SA 2XQWC 1ZJKA 4AYEA 1U5MA 2YBYA 2B5ID 1GHQB 1E88A 3TVJA 1HCCA 1OK9A 1TPGA 1QGBA 4KKDA 5HZPB 2O39C 3OXUD 1QUBA 2RL0A 1VVDA 2CG7A 1OJWA 2JGWA 4ZH1D 1GKGA 2RKYA 1UOTP 2V8EA 4FXGG 4AYIA 3GXEA 3GOVA 4F4OC 1G4FA 2G7IA 1G4GA 3R62A 2IZ3A 1GKNA 2WIIC 1OK2A 4A5WB 3KZJA 2W80A 2JRAA 1OJYA 1PPQA 5FO8C 1ELVA 1VVCA 2EC3A 3MQLA 1OK3A 1E5GA 2RLPA 2BZMA 2XWBF 1Q3XA 1GPZA 4PZ5A 3M7PA 2XRDA 3OP8A 5HYPA 1MD8A 2UWNA 4B2RA 2ERJA 3NFPI 3OEDC 3O8EB 1CKLA 4J38B 3ZD1A 2KMSA 5HYUB 5HYTB 2IZ4A 1LY2A 1O9AA 2YRAA 2LOJA 1HFIA 4C16A 3EJHA 3ZRZA 3ZD2A 4WJG2 4ONTD 3SW0X 1NWVA 4LOSA 4K12A 2XWJI 3IU3I 2CG6A 2XRBA 2EHFA 4DJZA 1H2QP 2KRIA 2QY0A 1H03P 3KXVA 4CSYA 3INBC 4MUCA 3T5OA 1FBRA 1TPMA 2MCYA 2MCZA 2RLQA 1C1ZA 1OK1A 2W81A 1H2PP 1TPNA
chains in the Genus database with same CATH superfamily
3ERBA 1SRZA 1E8BA 3CALA 3ZLEA 4MSLA 1H04P 1QO6A 2RKZA 1MD7A 4AYDA 4N7EA 2JGXA 2ZYCA 2CKUA 4LOTA 5JPMG 1HFHA 4JHSA 1Z92B 4AYMA 3IX0A 1SS2A 3RJ3D 3L89M 4IGDA 4YNXA 5I0QB 2A55A 1OJVA 4B2SA 2XQWC 1ZJKA 3FGRA 4AYEA 1U5MA 2YBYA 2B5ID 1GHQB 1E88A 3TVJA 1HCCA 1OK9A 1TPGA 1QGBA 4KKDA 5HZPB 2O39C 3OXUD 1QUBA 2RL0A 1VVDA 2CG7A 1OJWA 2JGWA 4ZH1D 1GKGA 2Y8SA 4BWCA 2RKYA 1UOTP 2V8EA 3CI0J 4FXGG 4AYIA 3GXEA 3GOVA 4F4OC 1G4FA 2G7IA 3WSXA 1G4GA 3R62A 2IZ3A 1GKNA 2WIIC 1RLHA 4PO7A 1OK2A 4A5WB 3ZLDA 3F6KA 3KZJA 2W80A 2JRAA 1OJYA 1PPQA 5FO8C 1ELVA 5DN5A 1VVCA 3VWOA 2EC3A 3MQLA 1OK3A 2Y8RA 2RLPA 1E5GA 2BZMA 2XWBF 1Q3XA 3K3TA 1GPZA 4PZ5A 3M7PA 2XRDA 3OP8A 5HYPA 1MD8A 2UWNA 4B2RA 3FGTA 2ERJA 3NFPI 3OEDC 3O8EB 1CKLA 4J38B 3ZD1A 2KMSA 5HYUB 5HYTB 2Y8TA 2IZ4A 1LY2A 1O9AA 2YRAA 2LOJA 1HFIA 5DN4A 4C16A 3EJHA 3ZRZA 3ZD2A 4WJG2 4ONTD 3WSYA 3SW0X 1NWVA 4LOSA 4K12A 2I2LA 4YIZA 2XWJI 3IU3I 2CG6A 2XRBA 2EHFA 4DJZA 1H2QP 2KRIA 2QY0A 1H03P 3KXVA 4CSYA 3INBC 4MUCA 3T5OA 1FBRA 1TPMA 2MCYA 2MCZA 2RLQA 2X2ZA 1C1ZA 1OK1A 4APLA 2W81A 3NJAA 1H2PP 1TPNA
chains in the Genus database with same CATH topology
3ERBA 1SRZA 1E8BA 3CALA 1H04P 1QO6A 2RKZA 1MD7A 4AYDA 2JGXA 2CKUA 4LOTA 5JPMG 1HFHA 4JHSA 1Z92B 4AYMA 3IX0A 1SS2A 3RJ3D 3L89M 4IGDA 4YNXA 5I0QB 2A55A 1OJVA 4B2SA 2XQWC 1ZJKA 4AYEA 1U5MA 2YBYA 2B5ID 1GHQB 1E88A 3TVJA 1HCCA 1OK9A 1TPGA 1QGBA 4KKDA 5HZPB 2O39C 3OXUD 1QUBA 2RL0A 1VVDA 2CG7A 1OJWA 2JGWA 4ZH1D 1GKGA 2RKYA 1UOTP 2V8EA 4FXGG 4AYIA 3GXEA 3GOVA 4F4OC 1G4FA 2G7IA 1G4GA 3R62A 2IZ3A 1GKNA 2WIIC 1OK2A 4A5WB 3KZJA 2W80A 2JRAA 1OJYA 1PPQA 5FO8C 1ELVA 1VVCA 2EC3A 3MQLA 1OK3A 1E5GA 2RLPA 2BZMA 2XWBF 1Q3XA 1GPZA 4PZ5A 3M7PA 2XRDA 3OP8A 5HYPA 1MD8A 2UWNA 4B2RA 2ERJA 3NFPI 3OEDC 3O8EB 1CKLA 4J38B 3ZD1A 2KMSA 5HYUB 5HYTB 2IZ4A 1LY2A 1O9AA 2YRAA 2LOJA 1HFIA 4C16A 3EJHA 3ZRZA 3ZD2A 4WJG2 4ONTD 3SW0X 1NWVA 4LOSA 4K12A 2XWJI 3IU3I 2CG6A 2XRBA 2EHFA 4DJZA 1H2QP 2KRIA 2QY0A 1H03P 3KXVA 4CSYA 3INBC 4MUCA 3T5OA 1FBRA 1TPMA 2MCYA 2MCZA 2RLQA 1C1ZA 1OK1A 2W81A 1H2PP 1TPNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ERB A;  1SRZ A;  1E8B A;  3CAL A;  1H04 P;  1QO6 A;  2RKZ A;  1MD7 A;  4AYD A;  2JGX A;  2CKU A;  4LOT A;  5JPM G;  1HFH A;  4JHS A;  1Z92 B;  4AYM A;  3IX0 A;  1SS2 A;  3RJ3 D;  3L89 M;  4IGD A;  4YNX A;  5I0Q B;  2A55 A;  1OJV A;  4B2S A;  2XQW C;  1ZJK A;  4AYE A;  1U5M A;  2YBY A;  2B5I D;  1GHQ B;  1E88 A;  3TVJ A;  1HCC A;  1OK9 A;  1TPG A;  1QGB A;  4KKD A;  5HZP B;  2O39 C;  3OXU D;  1QUB A;  2RL0 A;  1VVD A;  2CG7 A;  1OJW A;  2JGW A;  4ZH1 D;  1GKG A;  2RKY A;  1UOT P;  2V8E A;  4FXG G;  4AYI A;  3GXE A;  3GOV A;  4F4O C;  1G4F A;  2G7I A;  1G4G A;  3R62 A;  2IZ3 A;  1GKN A;  2WII C;  1OK2 A;  4A5W B;  3KZJ A;  2W80 A;  2JRA A;  1OJY A;  1PPQ A;  5FO8 C;  1ELV A;  1VVC A;  2EC3 A;  3MQL A;  1OK3 A;  1E5G A;  2RLP A;  2BZM A;  2XWB F;  1Q3X A;  1GPZ A;  4PZ5 A;  3M7P A;  2XRD A;  3OP8 A;  5HYP A;  1MD8 A;  2UWN A;  4B2R A;  2ERJ A;  3NFP I;  3OED C;  3O8E B;  1CKL A;  4J38 B;  3ZD1 A;  2KMS A;  5HYU B;  5HYT B;  2IZ4 A;  1LY2 A;  1O9A A;  2YRA A;  2LOJ A;  1HFI A;  4C16 A;  3EJH A;  3ZRZ A;  3ZD2 A;  4WJG 2;  4ONT D;  3SW0 X;  1NWV A;  4LOS A;  4K12 A;  2XWJ I;  3IU3 I;  2CG6 A;  2XRB A;  2EHF A;  4DJZ A;  1H2Q P;  2KRI A;  2QY0 A;  1H03 P;  3KXV A;  4CSY A;  3INB C;  4MUC A;  3T5O A;  1FBR A;  1TPM A;  2MCY A;  2MCZ A;  2RLQ A;  1C1Z A;  1OK1 A;  2W81 A;  1H2P P;  1TPN A; 
#chains in the Genus database with same CATH topology
 3ERB A;  1SRZ A;  1E8B A;  3CAL A;  3ZLE A;  4MSL A;  1H04 P;  1QO6 A;  2RKZ A;  1MD7 A;  4AYD A;  4N7E A;  2JGX A;  2ZYC A;  2CKU A;  4LOT A;  5JPM G;  1HFH A;  4JHS A;  1Z92 B;  4AYM A;  3IX0 A;  1SS2 A;  3RJ3 D;  3L89 M;  4IGD A;  4YNX A;  5I0Q B;  2A55 A;  1OJV A;  4B2S A;  2XQW C;  1ZJK A;  3FGR A;  4AYE A;  1U5M A;  2YBY A;  2B5I D;  1GHQ B;  1E88 A;  3TVJ A;  1HCC A;  1OK9 A;  1TPG A;  1QGB A;  4KKD A;  5HZP B;  2O39 C;  3OXU D;  1QUB A;  2RL0 A;  1VVD A;  2CG7 A;  1OJW A;  2JGW A;  4ZH1 D;  1GKG A;  2Y8S A;  4BWC A;  2RKY A;  1UOT P;  2V8E A;  3CI0 J;  4FXG G;  4AYI A;  3GXE A;  3GOV A;  4F4O C;  1G4F A;  2G7I A;  3WSX A;  1G4G A;  3R62 A;  2IZ3 A;  1GKN A;  2WII C;  1RLH A;  4PO7 A;  1OK2 A;  4A5W B;  3ZLD A;  3F6K A;  3KZJ A;  2W80 A;  2JRA A;  1OJY A;  1PPQ A;  5FO8 C;  1ELV A;  5DN5 A;  1VVC A;  3VWO A;  2EC3 A;  3MQL A;  1OK3 A;  2Y8R A;  2RLP A;  1E5G A;  2BZM A;  2XWB F;  1Q3X A;  3K3T A;  1GPZ A;  4PZ5 A;  3M7P A;  2XRD A;  3OP8 A;  5HYP A;  1MD8 A;  2UWN A;  4B2R A;  3FGT A;  2ERJ A;  3NFP I;  3OED C;  3O8E B;  1CKL A;  4J38 B;  3ZD1 A;  2KMS A;  5HYU B;  5HYT B;  2Y8T A;  2IZ4 A;  1LY2 A;  1O9A A;  2YRA A;  2LOJ A;  1HFI A;  5DN4 A;  4C16 A;  3EJH A;  3ZRZ A;  3ZD2 A;  4WJG 2;  4ONT D;  3WSY A;  3SW0 X;  1NWV A;  4LOS A;  4K12 A;  2I2L A;  4YIZ A;  2XWJ I;  3IU3 I;  2CG6 A;  2XRB A;  2EHF A;  4DJZ A;  1H2Q P;  2KRI A;  2QY0 A;  1H03 P;  3KXV A;  4CSY A;  3INB C;  4MUC A;  3T5O A;  1FBR A;  1TPM A;  2MCY A;  2MCZ A;  2RLQ A;  2X2Z A;  1C1Z A;  1OK1 A;  4APL A;  2W81 A;  3NJA A;  1H2P P;  1TPN A; 
#chains in the Genus database with same CATH homology
 3ERB A;  1SRZ A;  1E8B A;  3CAL A;  1H04 P;  1QO6 A;  2RKZ A;  1MD7 A;  4AYD A;  2JGX A;  2CKU A;  4LOT A;  5JPM G;  1HFH A;  4JHS A;  1Z92 B;  4AYM A;  3IX0 A;  1SS2 A;  3RJ3 D;  3L89 M;  4IGD A;  4YNX A;  5I0Q B;  2A55 A;  1OJV A;  4B2S A;  2XQW C;  1ZJK A;  4AYE A;  1U5M A;  2YBY A;  2B5I D;  1GHQ B;  1E88 A;  3TVJ A;  1HCC A;  1OK9 A;  1TPG A;  1QGB A;  4KKD A;  5HZP B;  2O39 C;  3OXU D;  1QUB A;  2RL0 A;  1VVD A;  2CG7 A;  1OJW A;  2JGW A;  4ZH1 D;  1GKG A;  2RKY A;  1UOT P;  2V8E A;  4FXG G;  4AYI A;  3GXE A;  3GOV A;  4F4O C;  1G4F A;  2G7I A;  1G4G A;  3R62 A;  2IZ3 A;  1GKN A;  2WII C;  1OK2 A;  4A5W B;  3KZJ A;  2W80 A;  2JRA A;  1OJY A;  1PPQ A;  5FO8 C;  1ELV A;  1VVC A;  2EC3 A;  3MQL A;  1OK3 A;  1E5G A;  2RLP A;  2BZM A;  2XWB F;  1Q3X A;  1GPZ A;  4PZ5 A;  3M7P A;  2XRD A;  3OP8 A;  5HYP A;  1MD8 A;  2UWN A;  4B2R A;  2ERJ A;  3NFP I;  3OED C;  3O8E B;  1CKL A;  4J38 B;  3ZD1 A;  2KMS A;  5HYU B;  5HYT B;  2IZ4 A;  1LY2 A;  1O9A A;  2YRA A;  2LOJ A;  1HFI A;  4C16 A;  3EJH A;  3ZRZ A;  3ZD2 A;  4WJG 2;  4ONT D;  3SW0 X;  1NWV A;  4LOS A;  4K12 A;  2XWJ I;  3IU3 I;  2CG6 A;  2XRB A;  2EHF A;  4DJZ A;  1H2Q P;  2KRI A;  2QY0 A;  1H03 P;  3KXV A;  4CSY A;  3INB C;  4MUC A;  3T5O A;  1FBR A;  1TPM A;  2MCY A;  2MCZ A;  2RLQ A;  1C1Z A;  1OK1 A;  2W81 A;  1H2P P;  1TPN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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