1GKNA

Structure determination and rational mutagenesis reveal binding surface of immune adherence receptor, cr1 (cd35)
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
128
structure length
128
Chain Sequence
EAEAHCQAPDHFLFAKLKTQTTASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRITYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
pubmed doi rcsb
molecule tags Complement
source organism Homo sapiens
molecule keywords COMPLEMENT RECEPTOR TYPE 1
total genus 14
structure length 128
sequence length 128
ec nomenclature
pdb deposition date 2001-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA02
1GKNA 5FO8C 4WJG2 4LOTA 2XRDA 2YBYA 3IX0A 1GPZA 3R62A 4CSYA 1MD7A 4A5WB 1FBRA 3ZRZA 1Q3XA 3GOVA 1SS2A 1E88A 4IGDA 3INBC 3ZD2A 5HYTB 3GXEA 1E8BA 4DJZA 4PZ5A 4AYEA 2W80A 2RLPA 4F4OC 1GHQB 1Z92B 1VVCA 4J38B 3O8EB 4AYMA 2G7IA 1HFIA 1U5MA 1QO6A 1NWVA 3MQLA 1ELVA 4KKDA 4AYDA 1OJYA 1MD8A 1CKLA 2XQWC 3NFPI 2B5ID 3OXUD 3OEDC 5HYUB 2RKZA 4B2RA 4K12A 2QY0A 1TPMA 1OK3A 1LY2A 1UOTP 2IZ4A 1GKGA 1HCCA 4YNXA 2BZMA 2JGXA 2O39C 2RKYA 1O9AA 2YRAA 1H04P 2KMSA 4ZH1D 1H2PP 2XRBA 1VVDA 2CKUA 3IU3I 1OK9A 2CG6A 3KXVA 5JPMG 2ERJA 3ZD1A 4C16A 1C1ZA 3L89M 2MCZA 5HYPA 3KZJA 1HFHA 2CG7A 4ONTD 2EHFA 3T5OA 1QGBA 4LOSA 2W81A 3ERBA 1H2QP 2XWJI 2WIIC 3RJ3D 1OK1A 4B2SA 2KRIA 1H03P 1PPQA 2EC3A 2IZ3A 1TPNA 1TPGA 2V8EA 1QUBA 1G4FA 1G4GA 5HZPB 1OK2A 2UWNA 4MUCA 3TVJA 2RLQA 1E5GA 2RL0A 2LOJA 2XWBF 2JRAA 3CALA 3M7PA 3SW0X 2JGWA 2A55A 2MCYA 5I0QB 1OJVA 3EJHA 4FXGG 1SRZA 4AYIA 4JHSA 3OP8A 1ZJKA 1OJWA
chains in the Genus database with same CATH superfamily
1GKNA 5FO8C 4WJG2 4LOTA 2XRDA 2YBYA 3IX0A 1GPZA 3R62A 4CSYA 1MD7A 4A5WB 1FBRA 3ZRZA 1Q3XA 4N7EA 3GOVA 1SS2A 1E88A 4IGDA 3INBC 2X2ZA 3ZD2A 5HYTB 3GXEA 1E8BA 4DJZA 4PZ5A 4AYEA 2W80A 2ZYCA 2RLPA 4F4OC 1GHQB 1Z92B 2I2LA 1VVCA 4J38B 3O8EB 4AYMA 2G7IA 1HFIA 1U5MA 1QO6A 1NWVA 3MQLA 1ELVA 4KKDA 3WSXA 4AYDA 1OJYA 1MD8A 1CKLA 2XQWC 3NFPI 2B5ID 3OXUD 3OEDC 4BWCA 5HYUB 2RKZA 4B2RA 2Y8RA 4K12A 2QY0A 1TPMA 1OK3A 1RLHA 1LY2A 1UOTP 2IZ4A 3CI0J 1GKGA 1HCCA 4YNXA 2BZMA 2JGXA 2O39C 2RKYA 1O9AA 2YRAA 3NJAA 1H04P 2KMSA 4ZH1D 1H2PP 2XRBA 1VVDA 2CKUA 3IU3I 2Y8TA 1OK9A 2CG6A 3KXVA 5JPMG 2ERJA 3ZD1A 4C16A 3K3TA 1C1ZA 3L89M 2MCZA 3F6KA 3KZJA 5HYPA 1HFHA 2CG7A 3VWOA 4ONTD 2EHFA 3T5OA 4YIZA 1QGBA 2Y8SA 4LOSA 2W81A 3ERBA 3FGRA 1H2QP 2XWJI 2WIIC 3RJ3D 4MSLA 4APLA 1OK1A 4B2SA 2KRIA 1H03P 1PPQA 2EC3A 2IZ3A 1TPNA 1TPGA 2V8EA 1QUBA 1G4FA 1G4GA 3WSYA 5HZPB 1OK2A 2UWNA 4MUCA 3TVJA 2RLQA 1E5GA 2RL0A 2LOJA 3ZLEA 2XWBF 5DN5A 5DN4A 3ZLDA 2JRAA 3CALA 3FGTA 3M7PA 3SW0X 2JGWA 2A55A 2MCYA 5I0QB 1OJVA 3EJHA 4FXGG 1SRZA 4AYIA 4JHSA 4PO7A 3OP8A 1ZJKA 1OJWA
chains in the Genus database with same CATH topology
1GKNA 5FO8C 4WJG2 4LOTA 2XRDA 2YBYA 3IX0A 1GPZA 3R62A 4CSYA 1MD7A 4A5WB 1FBRA 3ZRZA 1Q3XA 3GOVA 1SS2A 1E88A 4IGDA 3INBC 3ZD2A 5HYTB 3GXEA 1E8BA 4DJZA 4PZ5A 4AYEA 2W80A 2RLPA 4F4OC 1GHQB 1Z92B 1VVCA 4J38B 3O8EB 4AYMA 2G7IA 1HFIA 1U5MA 1QO6A 1NWVA 3MQLA 1ELVA 4KKDA 4AYDA 1OJYA 1MD8A 1CKLA 2XQWC 3NFPI 2B5ID 3OXUD 3OEDC 5HYUB 2RKZA 4B2RA 4K12A 2QY0A 1TPMA 1OK3A 1LY2A 1UOTP 2IZ4A 1GKGA 1HCCA 4YNXA 2BZMA 2JGXA 2O39C 2RKYA 1O9AA 2YRAA 1H04P 2KMSA 4ZH1D 1H2PP 2XRBA 1VVDA 2CKUA 3IU3I 1OK9A 2CG6A 3KXVA 5JPMG 2ERJA 3ZD1A 4C16A 1C1ZA 3L89M 2MCZA 5HYPA 3KZJA 1HFHA 2CG7A 4ONTD 2EHFA 3T5OA 1QGBA 4LOSA 2W81A 3ERBA 1H2QP 2XWJI 2WIIC 3RJ3D 1OK1A 4B2SA 2KRIA 1H03P 1PPQA 2EC3A 2IZ3A 1TPNA 1TPGA 2V8EA 1QUBA 1G4FA 1G4GA 5HZPB 1OK2A 2UWNA 4MUCA 3TVJA 2RLQA 1E5GA 2RL0A 2LOJA 2XWBF 2JRAA 3CALA 3M7PA 3SW0X 2JGWA 2A55A 2MCYA 5I0QB 1OJVA 3EJHA 4FXGG 1SRZA 4AYIA 4JHSA 3OP8A 1ZJKA 1OJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKN A;  5FO8 C;  4WJG 2;  4LOT A;  2XRD A;  2YBY A;  3IX0 A;  1GPZ A;  3R62 A;  4CSY A;  1MD7 A;  4A5W B;  1FBR A;  3ZRZ A;  1Q3X A;  3GOV A;  1SS2 A;  1E88 A;  4IGD A;  3INB C;  3ZD2 A;  5HYT B;  3GXE A;  1E8B A;  4DJZ A;  4PZ5 A;  4AYE A;  2W80 A;  2RLP A;  4F4O C;  1GHQ B;  1Z92 B;  1VVC A;  4J38 B;  3O8E B;  4AYM A;  2G7I A;  1HFI A;  1U5M A;  1QO6 A;  1NWV A;  3MQL A;  1ELV A;  4KKD A;  4AYD A;  1OJY A;  1MD8 A;  1CKL A;  2XQW C;  3NFP I;  2B5I D;  3OXU D;  3OED C;  5HYU B;  2RKZ A;  4B2R A;  4K12 A;  2QY0 A;  1TPM A;  1OK3 A;  1LY2 A;  1UOT P;  2IZ4 A;  1GKG A;  1HCC A;  4YNX A;  2BZM A;  2JGX A;  2O39 C;  2RKY A;  1O9A A;  2YRA A;  1H04 P;  2KMS A;  4ZH1 D;  1H2P P;  2XRB A;  1VVD A;  2CKU A;  3IU3 I;  1OK9 A;  2CG6 A;  3KXV A;  5JPM G;  2ERJ A;  3ZD1 A;  4C16 A;  1C1Z A;  3L89 M;  2MCZ A;  5HYP A;  3KZJ A;  1HFH A;  2CG7 A;  4ONT D;  2EHF A;  3T5O A;  1QGB A;  4LOS A;  2W81 A;  3ERB A;  1H2Q P;  2XWJ I;  2WII C;  3RJ3 D;  1OK1 A;  4B2S A;  2KRI A;  1H03 P;  1PPQ A;  2EC3 A;  2IZ3 A;  1TPN A;  1TPG A;  2V8E A;  1QUB A;  1G4F A;  1G4G A;  5HZP B;  1OK2 A;  2UWN A;  4MUC A;  3TVJ A;  2RLQ A;  1E5G A;  2RL0 A;  2LOJ A;  2XWB F;  2JRA A;  3CAL A;  3M7P A;  3SW0 X;  2JGW A;  2A55 A;  2MCY A;  5I0Q B;  1OJV A;  3EJH A;  4FXG G;  1SRZ A;  4AYI A;  4JHS A;  3OP8 A;  1ZJK A;  1OJW A; 
#chains in the Genus database with same CATH topology
 1GKN A;  5FO8 C;  4WJG 2;  4LOT A;  2XRD A;  2YBY A;  3IX0 A;  1GPZ A;  3R62 A;  4CSY A;  1MD7 A;  4A5W B;  1FBR A;  3ZRZ A;  1Q3X A;  4N7E A;  3GOV A;  1SS2 A;  1E88 A;  4IGD A;  3INB C;  2X2Z A;  3ZD2 A;  5HYT B;  3GXE A;  1E8B A;  4DJZ A;  4PZ5 A;  4AYE A;  2W80 A;  2ZYC A;  2RLP A;  4F4O C;  1GHQ B;  1Z92 B;  2I2L A;  1VVC A;  4J38 B;  3O8E B;  4AYM A;  2G7I A;  1HFI A;  1U5M A;  1QO6 A;  1NWV A;  3MQL A;  1ELV A;  4KKD A;  3WSX A;  4AYD A;  1OJY A;  1MD8 A;  1CKL A;  2XQW C;  3NFP I;  2B5I D;  3OXU D;  3OED C;  4BWC A;  5HYU B;  2RKZ A;  4B2R A;  2Y8R A;  4K12 A;  2QY0 A;  1TPM A;  1OK3 A;  1RLH A;  1LY2 A;  1UOT P;  2IZ4 A;  3CI0 J;  1GKG A;  1HCC A;  4YNX A;  2BZM A;  2JGX A;  2O39 C;  2RKY A;  1O9A A;  2YRA A;  3NJA A;  1H04 P;  2KMS A;  4ZH1 D;  1H2P P;  2XRB A;  1VVD A;  2CKU A;  3IU3 I;  2Y8T A;  1OK9 A;  2CG6 A;  3KXV A;  5JPM G;  2ERJ A;  3ZD1 A;  4C16 A;  3K3T A;  1C1Z A;  3L89 M;  2MCZ A;  3F6K A;  3KZJ A;  5HYP A;  1HFH A;  2CG7 A;  3VWO A;  4ONT D;  2EHF A;  3T5O A;  4YIZ A;  1QGB A;  2Y8S A;  4LOS A;  2W81 A;  3ERB A;  3FGR A;  1H2Q P;  2XWJ I;  2WII C;  3RJ3 D;  4MSL A;  4APL A;  1OK1 A;  4B2S A;  2KRI A;  1H03 P;  1PPQ A;  2EC3 A;  2IZ3 A;  1TPN A;  1TPG A;  2V8E A;  1QUB A;  1G4F A;  1G4G A;  3WSY A;  5HZP B;  1OK2 A;  2UWN A;  4MUC A;  3TVJ A;  2RLQ A;  1E5G A;  2RL0 A;  2LOJ A;  3ZLE A;  2XWB F;  5DN5 A;  5DN4 A;  3ZLD A;  2JRA A;  3CAL A;  3FGT A;  3M7P A;  3SW0 X;  2JGW A;  2A55 A;  2MCY A;  5I0Q B;  1OJV A;  3EJH A;  4FXG G;  1SRZ A;  4AYI A;  4JHS A;  4PO7 A;  3OP8 A;  1ZJK A;  1OJW A; 
#chains in the Genus database with same CATH homology
 1GKN A;  5FO8 C;  4WJG 2;  4LOT A;  2XRD A;  2YBY A;  3IX0 A;  1GPZ A;  3R62 A;  4CSY A;  1MD7 A;  4A5W B;  1FBR A;  3ZRZ A;  1Q3X A;  3GOV A;  1SS2 A;  1E88 A;  4IGD A;  3INB C;  3ZD2 A;  5HYT B;  3GXE A;  1E8B A;  4DJZ A;  4PZ5 A;  4AYE A;  2W80 A;  2RLP A;  4F4O C;  1GHQ B;  1Z92 B;  1VVC A;  4J38 B;  3O8E B;  4AYM A;  2G7I A;  1HFI A;  1U5M A;  1QO6 A;  1NWV A;  3MQL A;  1ELV A;  4KKD A;  4AYD A;  1OJY A;  1MD8 A;  1CKL A;  2XQW C;  3NFP I;  2B5I D;  3OXU D;  3OED C;  5HYU B;  2RKZ A;  4B2R A;  4K12 A;  2QY0 A;  1TPM A;  1OK3 A;  1LY2 A;  1UOT P;  2IZ4 A;  1GKG A;  1HCC A;  4YNX A;  2BZM A;  2JGX A;  2O39 C;  2RKY A;  1O9A A;  2YRA A;  1H04 P;  2KMS A;  4ZH1 D;  1H2P P;  2XRB A;  1VVD A;  2CKU A;  3IU3 I;  1OK9 A;  2CG6 A;  3KXV A;  5JPM G;  2ERJ A;  3ZD1 A;  4C16 A;  1C1Z A;  3L89 M;  2MCZ A;  5HYP A;  3KZJ A;  1HFH A;  2CG7 A;  4ONT D;  2EHF A;  3T5O A;  1QGB A;  4LOS A;  2W81 A;  3ERB A;  1H2Q P;  2XWJ I;  2WII C;  3RJ3 D;  1OK1 A;  4B2S A;  2KRI A;  1H03 P;  1PPQ A;  2EC3 A;  2IZ3 A;  1TPN A;  1TPG A;  2V8E A;  1QUB A;  1G4F A;  1G4G A;  5HZP B;  1OK2 A;  2UWN A;  4MUC A;  3TVJ A;  2RLQ A;  1E5G A;  2RL0 A;  2LOJ A;  2XWB F;  2JRA A;  3CAL A;  3M7P A;  3SW0 X;  2JGW A;  2A55 A;  2MCY A;  5I0Q B;  1OJV A;  3EJH A;  4FXG G;  1SRZ A;  4AYI A;  4JHS A;  3OP8 A;  1ZJK A;  1OJW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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