1HFHA

Solution structure of a pair of complement modules by nuclear magnetic resonance
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
120
structure length
120
Chain Sequence
EKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of a pair of complement modules by nuclear magnetic resonance.
pubmed doi rcsb
molecule tags Glycoprotein
source organism Homo sapiens
molecule keywords FACTOR H, 15TH AND 16TH C-MODULE PAIR
total genus 12
structure length 120
sequence length 120
ec nomenclature
pdb deposition date 1993-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1hfhA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1hfhA01
2B5ID 2MCYA 2EHFA 3ZD1A 2KMSA 1H2QP 1GPZA 2IZ4A 2O39C 1C1ZA 3O8EB 3KZJA 3RJ3D 1MD8A 1GHQB 3ERBA 4J38B 2RLPA 4YNXA 1OK9A 4FXGG 4WJG2 3GOVA 5FO8C 1G4FA 2JRAA 2G7IA 4A5WB 4ZH1D 2XRDA 1LY2A 3OXUD 1QUBA 3L89M 4KKDA 1H2PP 3OEDC 4LOSA 2A55A 1QGBA 1VVDA 1OJYA 4B2SA 1ZJKA 3GXEA 2RL0A 1FBRA 1GKGA 2XWBF 2MCZA 3OP8A 3KXVA 4ONTD 2XQWC 2KRIA 4CSYA 4B2RA 4AYIA 1OK2A 2XRBA 4IGDA 1O9AA 1OJWA 4C16A 4PZ5A 1TPNA 2CKUA 2RKYA 3SW0X 2QY0A 2ERJA 1H04P 1E5GA 1VVCA 2UWNA 1HFHA 2RLQA 2JGWA 5HYTB 1TPGA 3ZRZA 4AYEA 5HYUB 1GKNA 5I0QB 3IX0A 3INBC 1OJVA 3R62A 1H03P 1OK3A 2XWJI 2YRAA 1SRZA 1U5MA 2W81A 2CG7A 3T5OA 4LOTA 1Q3XA 1MD7A 2CG6A 4JHSA 5HZPB 2IZ3A 4MUCA 1PPQA 4AYMA 1SS2A 3IU3I 3NFPI 2RKZA 3CALA 1HFIA 4F4OC 2YBYA 1E88A 1UOTP 2JGXA 1HCCA 1CKLA 2WIIC 5JPMG 4AYDA 1OK1A 3ZD2A 1E8BA 4DJZA 2V8EA 1Z92B 2BZMA 3TVJA 1QO6A 3MQLA 1NWVA 3M7PA 2LOJA 4K12A 3EJHA 2EC3A 1ELVA 1G4GA 1TPMA 5HYPA 2W80A
chains in the Genus database with same CATH superfamily
2B5ID 2MCYA 2EHFA 2ZYCA 3ZD1A 2Y8SA 2KMSA 1H2QP 1GPZA 2IZ4A 2O39C 1C1ZA 3O8EB 3KZJA 3RJ3D 1MD8A 1GHQB 3ERBA 3CI0J 4J38B 2RLPA 4YNXA 1OK9A 4FXGG 4WJG2 2Y8TA 3GOVA 5FO8C 3FGRA 1G4FA 2JRAA 2G7IA 4A5WB 4ZH1D 2XRDA 1LY2A 3OXUD 4APLA 1QUBA 3L89M 3FGTA 4KKDA 1H2PP 4BWCA 3OEDC 4LOSA 2A55A 1QGBA 1VVDA 1OJYA 4B2SA 1ZJKA 3GXEA 2RL0A 1FBRA 3NJAA 2XWBF 1GKGA 1RLHA 2MCZA 3F6KA 3OP8A 3KXVA 5DN4A 4ONTD 2XQWC 2KRIA 3WSYA 4B2RA 4CSYA 4AYIA 1OK2A 2XRBA 4IGDA 1O9AA 1OJWA 4C16A 4PZ5A 1TPNA 2CKUA 2RKYA 3SW0X 2QY0A 2ERJA 1H04P 1E5GA 2Y8RA 3K3TA 1VVCA 2UWNA 1HFHA 2RLQA 4YIZA 2JGWA 5HYTB 3ZLDA 1TPGA 3ZLEA 3ZRZA 4AYEA 5HYUB 4PO7A 5I0QB 1GKNA 3IX0A 3INBC 1OJVA 3R62A 1H03P 1OK3A 2XWJI 2I2LA 2YRAA 1SRZA 1U5MA 2W81A 2CG7A 3T5OA 4LOTA 1Q3XA 1MD7A 2CG6A 4JHSA 5HZPB 2IZ3A 4MUCA 1PPQA 3WSXA 4AYMA 1SS2A 2X2ZA 3IU3I 3NFPI 2RKZA 3CALA 1HFIA 4F4OC 4MSLA 2YBYA 1E88A 1UOTP 2JGXA 1HCCA 1CKLA 2WIIC 5JPMG 4N7EA 4AYDA 1OK1A 3ZD2A 1E8BA 4DJZA 2V8EA 1Z92B 2BZMA 3TVJA 1QO6A 3MQLA 1NWVA 3M7PA 2LOJA 4K12A 3EJHA 3VWOA 2EC3A 5DN5A 1ELVA 1G4GA 1TPMA 5HYPA 2W80A
chains in the Genus database with same CATH topology
2B5ID 2MCYA 2EHFA 3ZD1A 2KMSA 1H2QP 1GPZA 2IZ4A 2O39C 1C1ZA 3O8EB 3KZJA 3RJ3D 1MD8A 1GHQB 3ERBA 4J38B 2RLPA 4YNXA 1OK9A 4FXGG 4WJG2 3GOVA 5FO8C 1G4FA 2JRAA 2G7IA 4A5WB 4ZH1D 2XRDA 1LY2A 3OXUD 1QUBA 3L89M 4KKDA 1H2PP 3OEDC 4LOSA 2A55A 1QGBA 1VVDA 1OJYA 4B2SA 1ZJKA 3GXEA 2RL0A 1FBRA 1GKGA 2XWBF 2MCZA 3OP8A 3KXVA 4ONTD 2XQWC 2KRIA 4CSYA 4B2RA 4AYIA 1OK2A 2XRBA 4IGDA 1O9AA 1OJWA 4C16A 4PZ5A 1TPNA 2CKUA 2RKYA 3SW0X 2QY0A 2ERJA 1H04P 1E5GA 1VVCA 2UWNA 1HFHA 2RLQA 2JGWA 5HYTB 1TPGA 3ZRZA 4AYEA 5HYUB 1GKNA 5I0QB 3IX0A 3INBC 1OJVA 3R62A 1H03P 1OK3A 2XWJI 2YRAA 1SRZA 1U5MA 2W81A 2CG7A 3T5OA 4LOTA 1Q3XA 1MD7A 2CG6A 4JHSA 5HZPB 2IZ3A 4MUCA 1PPQA 4AYMA 1SS2A 3IU3I 3NFPI 2RKZA 3CALA 1HFIA 4F4OC 2YBYA 1E88A 1UOTP 2JGXA 1HCCA 1CKLA 2WIIC 5JPMG 4AYDA 1OK1A 3ZD2A 1E8BA 4DJZA 2V8EA 1Z92B 2BZMA 3TVJA 1QO6A 3MQLA 1NWVA 3M7PA 2LOJA 4K12A 3EJHA 2EC3A 1ELVA 1G4GA 1TPMA 5HYPA 2W80A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B5I D;  2MCY A;  2EHF A;  3ZD1 A;  2KMS A;  1H2Q P;  1GPZ A;  2IZ4 A;  2O39 C;  1C1Z A;  3O8E B;  3KZJ A;  3RJ3 D;  1MD8 A;  1GHQ B;  3ERB A;  4J38 B;  2RLP A;  4YNX A;  1OK9 A;  4FXG G;  4WJG 2;  3GOV A;  5FO8 C;  1G4F A;  2JRA A;  2G7I A;  4A5W B;  4ZH1 D;  2XRD A;  1LY2 A;  3OXU D;  1QUB A;  3L89 M;  4KKD A;  1H2P P;  3OED C;  4LOS A;  2A55 A;  1QGB A;  1VVD A;  1OJY A;  4B2S A;  1ZJK A;  3GXE A;  2RL0 A;  1FBR A;  1GKG A;  2XWB F;  2MCZ A;  3OP8 A;  3KXV A;  4ONT D;  2XQW C;  2KRI A;  4CSY A;  4B2R A;  4AYI A;  1OK2 A;  2XRB A;  4IGD A;  1O9A A;  1OJW A;  4C16 A;  4PZ5 A;  1TPN A;  2CKU A;  2RKY A;  3SW0 X;  2QY0 A;  2ERJ A;  1H04 P;  1E5G A;  1VVC A;  2UWN A;  1HFH A;  2RLQ A;  2JGW A;  5HYT B;  1TPG A;  3ZRZ A;  4AYE A;  5HYU B;  1GKN A;  5I0Q B;  3IX0 A;  3INB C;  1OJV A;  3R62 A;  1H03 P;  1OK3 A;  2XWJ I;  2YRA A;  1SRZ A;  1U5M A;  2W81 A;  2CG7 A;  3T5O A;  4LOT A;  1Q3X A;  1MD7 A;  2CG6 A;  4JHS A;  5HZP B;  2IZ3 A;  4MUC A;  1PPQ A;  4AYM A;  1SS2 A;  3IU3 I;  3NFP I;  2RKZ A;  3CAL A;  1HFI A;  4F4O C;  2YBY A;  1E88 A;  1UOT P;  2JGX A;  1HCC A;  1CKL A;  2WII C;  5JPM G;  4AYD A;  1OK1 A;  3ZD2 A;  1E8B A;  4DJZ A;  2V8E A;  1Z92 B;  2BZM A;  3TVJ A;  1QO6 A;  3MQL A;  1NWV A;  3M7P A;  2LOJ A;  4K12 A;  3EJH A;  2EC3 A;  1ELV A;  1G4G A;  1TPM A;  5HYP A;  2W80 A; 
#chains in the Genus database with same CATH topology
 2B5I D;  2MCY A;  2EHF A;  2ZYC A;  3ZD1 A;  2Y8S A;  2KMS A;  1H2Q P;  1GPZ A;  2IZ4 A;  2O39 C;  1C1Z A;  3O8E B;  3KZJ A;  3RJ3 D;  1MD8 A;  1GHQ B;  3ERB A;  3CI0 J;  4J38 B;  2RLP A;  4YNX A;  1OK9 A;  4FXG G;  4WJG 2;  2Y8T A;  3GOV A;  5FO8 C;  3FGR A;  1G4F A;  2JRA A;  2G7I A;  4A5W B;  4ZH1 D;  2XRD A;  1LY2 A;  3OXU D;  4APL A;  1QUB A;  3L89 M;  3FGT A;  4KKD A;  1H2P P;  4BWC A;  3OED C;  4LOS A;  2A55 A;  1QGB A;  1VVD A;  1OJY A;  4B2S A;  1ZJK A;  3GXE A;  2RL0 A;  1FBR A;  3NJA A;  2XWB F;  1GKG A;  1RLH A;  2MCZ A;  3F6K A;  3OP8 A;  3KXV A;  5DN4 A;  4ONT D;  2XQW C;  2KRI A;  3WSY A;  4B2R A;  4CSY A;  4AYI A;  1OK2 A;  2XRB A;  4IGD A;  1O9A A;  1OJW A;  4C16 A;  4PZ5 A;  1TPN A;  2CKU A;  2RKY A;  3SW0 X;  2QY0 A;  2ERJ A;  1H04 P;  1E5G A;  2Y8R A;  3K3T A;  1VVC A;  2UWN A;  1HFH A;  2RLQ A;  4YIZ A;  2JGW A;  5HYT B;  3ZLD A;  1TPG A;  3ZLE A;  3ZRZ A;  4AYE A;  5HYU B;  4PO7 A;  5I0Q B;  1GKN A;  3IX0 A;  3INB C;  1OJV A;  3R62 A;  1H03 P;  1OK3 A;  2XWJ I;  2I2L A;  2YRA A;  1SRZ A;  1U5M A;  2W81 A;  2CG7 A;  3T5O A;  4LOT A;  1Q3X A;  1MD7 A;  2CG6 A;  4JHS A;  5HZP B;  2IZ3 A;  4MUC A;  1PPQ A;  3WSX A;  4AYM A;  1SS2 A;  2X2Z A;  3IU3 I;  3NFP I;  2RKZ A;  3CAL A;  1HFI A;  4F4O C;  4MSL A;  2YBY A;  1E88 A;  1UOT P;  2JGX A;  1HCC A;  1CKL A;  2WII C;  5JPM G;  4N7E A;  4AYD A;  1OK1 A;  3ZD2 A;  1E8B A;  4DJZ A;  2V8E A;  1Z92 B;  2BZM A;  3TVJ A;  1QO6 A;  3MQL A;  1NWV A;  3M7P A;  2LOJ A;  4K12 A;  3EJH A;  3VWO A;  2EC3 A;  5DN5 A;  1ELV A;  1G4G A;  1TPM A;  5HYP A;  2W80 A; 
#chains in the Genus database with same CATH homology
 2B5I D;  2MCY A;  2EHF A;  3ZD1 A;  2KMS A;  1H2Q P;  1GPZ A;  2IZ4 A;  2O39 C;  1C1Z A;  3O8E B;  3KZJ A;  3RJ3 D;  1MD8 A;  1GHQ B;  3ERB A;  4J38 B;  2RLP A;  4YNX A;  1OK9 A;  4FXG G;  4WJG 2;  3GOV A;  5FO8 C;  1G4F A;  2JRA A;  2G7I A;  4A5W B;  4ZH1 D;  2XRD A;  1LY2 A;  3OXU D;  1QUB A;  3L89 M;  4KKD A;  1H2P P;  3OED C;  4LOS A;  2A55 A;  1QGB A;  1VVD A;  1OJY A;  4B2S A;  1ZJK A;  3GXE A;  2RL0 A;  1FBR A;  1GKG A;  2XWB F;  2MCZ A;  3OP8 A;  3KXV A;  4ONT D;  2XQW C;  2KRI A;  4CSY A;  4B2R A;  4AYI A;  1OK2 A;  2XRB A;  4IGD A;  1O9A A;  1OJW A;  4C16 A;  4PZ5 A;  1TPN A;  2CKU A;  2RKY A;  3SW0 X;  2QY0 A;  2ERJ A;  1H04 P;  1E5G A;  1VVC A;  2UWN A;  1HFH A;  2RLQ A;  2JGW A;  5HYT B;  1TPG A;  3ZRZ A;  4AYE A;  5HYU B;  1GKN A;  5I0Q B;  3IX0 A;  3INB C;  1OJV A;  3R62 A;  1H03 P;  1OK3 A;  2XWJ I;  2YRA A;  1SRZ A;  1U5M A;  2W81 A;  2CG7 A;  3T5O A;  4LOT A;  1Q3X A;  1MD7 A;  2CG6 A;  4JHS A;  5HZP B;  2IZ3 A;  4MUC A;  1PPQ A;  4AYM A;  1SS2 A;  3IU3 I;  3NFP I;  2RKZ A;  3CAL A;  1HFI A;  4F4O C;  2YBY A;  1E88 A;  1UOT P;  2JGX A;  1HCC A;  1CKL A;  2WII C;  5JPM G;  4AYD A;  1OK1 A;  3ZD2 A;  1E8B A;  4DJZ A;  2V8E A;  1Z92 B;  2BZM A;  3TVJ A;  1QO6 A;  3MQL A;  1NWV A;  3M7P A;  2LOJ A;  4K12 A;  3EJH A;  2EC3 A;  1ELV A;  1G4G A;  1TPM A;  5HYP A;  2W80 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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