1HFIA

Solution structure of a pair of complement modules by nuclear magnetic resonance
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
62
structure length
62
Chain Sequence
EKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of a pair of complement modules by nuclear magnetic resonance.
pubmed doi rcsb
molecule tags Glycoprotein
source organism Homo sapiens
molecule keywords FACTOR H, 15TH C-MODULE PAIR
total genus 7
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 1993-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1hfiA00
4J38B 1VVCA 2CG7A 1GKGA 2B5ID 2W81A 3KXVA 5I0QB 3GOVA 2XRDA 3O8EB 2UWNA 3GXEA 2QY0A 3CALA 1E8BA 1OK1A 1OK9A 3R62A 2RLPA 2RL0A 2G7IA 3OEDC 4AYEA 3M7PA 5HYTB 1H2QP 2O39C 3IX0A 2MCZA 4LOTA 1NWVA 4ZH1D 4KKDA 3KZJA 2CKUA 2XRBA 1H2PP 3OXUD 2JGWA 3NFPI 2XQWC 1PPQA 4AYDA 5HZPB 1G4FA 2LOJA 1OJWA 2KRIA 1H04P 1MD7A 2W80A 4MUCA 4A5WB 3MQLA 1HCCA 3INBC 1SRZA 1QUBA 1MD8A 1HFIA 2JRAA 1OJYA 5HYUB 1OK3A 1E88A 1TPMA 1GHQB 3SW0X 2KMSA 2YRAA 1GKNA 3ZD2A 1OK2A 3RJ3D 1E5GA 1LY2A 1ZJKA 1HFHA 5FO8C 1G4GA 2JGXA 3IU3I 4YNXA 1CKLA 1QO6A 1OJVA 4AYIA 4LOSA 4WJG2 1O9AA 1GPZA 4CSYA 2CG6A 3ZD1A 2EC3A 1H03P 1UOTP 4FXGG 2XWBF 2MCYA 3OP8A 2V8EA 4F4OC 4AYMA 2IZ3A 2YBYA 4IGDA 4ONTD 5JPMG 3L89M 2EHFA 4B2SA 1VVDA 1FBRA 4DJZA 1SS2A 1QGBA 2RLQA 3ERBA 1TPGA 2RKYA 2IZ4A 3T5OA 3EJHA 4PZ5A 1Q3XA 4B2RA 1ELVA 2WIIC 3TVJA 5HYPA 2BZMA 1C1ZA 3ZRZA 4JHSA 2A55A 4C16A 1TPNA 4K12A 2ERJA 1Z92B 1U5MA 2XWJI 2RKZA
chains in the Genus database with same CATH superfamily
4J38B 1VVCA 2CG7A 1GKGA 2B5ID 2W81A 3KXVA 5I0QB 3GOVA 2XRDA 3O8EB 2UWNA 3GXEA 2QY0A 3CALA 1E8BA 2X2ZA 1OK1A 3WSXA 1OK9A 3R62A 2RLPA 2RL0A 2G7IA 3FGRA 3FGTA 3OEDC 1RLHA 4AYEA 3M7PA 5HYTB 1H2QP 2O39C 3IX0A 2MCZA 4LOTA 1NWVA 4ZH1D 4KKDA 3KZJA 2CKUA 5DN5A 2XRBA 1H2PP 3OXUD 2JGWA 3ZLDA 3NFPI 2XQWC 1PPQA 2Y8SA 4AYDA 5HZPB 1G4FA 2LOJA 1OJWA 2KRIA 1H04P 1MD7A 2W80A 4MUCA 4A5WB 3MQLA 4PO7A 1HCCA 2I2LA 2ZYCA 3INBC 1SRZA 4YIZA 1QUBA 1MD8A 1HFIA 2JRAA 1OJYA 3F6KA 5HYUB 1OK3A 1E88A 1TPMA 1GHQB 3SW0X 2KMSA 2Y8RA 2YRAA 1GKNA 3ZD2A 3CI0J 1OK2A 3RJ3D 1E5GA 1LY2A 1ZJKA 1HFHA 5FO8C 1G4GA 2JGXA 3IU3I 4YNXA 1CKLA 1QO6A 1OJVA 4AYIA 4LOSA 4WJG2 1O9AA 1GPZA 4CSYA 3ZLEA 2CG6A 3ZD1A 2EC3A 1H03P 1UOTP 4FXGG 2XWBF 3K3TA 2MCYA 4BWCA 3OP8A 2V8EA 4F4OC 4AYMA 2IZ3A 2YBYA 5DN4A 2Y8TA 4IGDA 4ONTD 5JPMG 3L89M 4MSLA 2EHFA 4B2SA 1VVDA 3WSYA 1FBRA 4DJZA 1SS2A 1QGBA 2RLQA 3ERBA 1TPGA 2RKYA 2IZ4A 3T5OA 3EJHA 4PZ5A 1Q3XA 4N7EA 1ELVA 4B2RA 2WIIC 3TVJA 5HYPA 2BZMA 1C1ZA 3VWOA 3ZRZA 4JHSA 3NJAA 4APLA 2A55A 4C16A 1TPNA 4K12A 2ERJA 1Z92B 1U5MA 2XWJI 2RKZA
chains in the Genus database with same CATH topology
4J38B 1VVCA 2CG7A 1GKGA 2B5ID 2W81A 3KXVA 5I0QB 3GOVA 2XRDA 3O8EB 2UWNA 3GXEA 2QY0A 3CALA 1E8BA 1OK1A 1OK9A 3R62A 2RLPA 2RL0A 2G7IA 3OEDC 4AYEA 3M7PA 5HYTB 1H2QP 2O39C 3IX0A 2MCZA 4LOTA 1NWVA 4ZH1D 4KKDA 3KZJA 2CKUA 2XRBA 1H2PP 3OXUD 2JGWA 3NFPI 2XQWC 1PPQA 4AYDA 5HZPB 1G4FA 2LOJA 1OJWA 2KRIA 1H04P 1MD7A 2W80A 4MUCA 4A5WB 3MQLA 1HCCA 3INBC 1SRZA 1QUBA 1MD8A 1HFIA 2JRAA 1OJYA 5HYUB 1OK3A 1E88A 1TPMA 1GHQB 3SW0X 2KMSA 2YRAA 1GKNA 3ZD2A 1OK2A 3RJ3D 1E5GA 1LY2A 1ZJKA 1HFHA 5FO8C 1G4GA 2JGXA 3IU3I 4YNXA 1CKLA 1QO6A 1OJVA 4AYIA 4LOSA 4WJG2 1O9AA 1GPZA 4CSYA 2CG6A 3ZD1A 2EC3A 1H03P 1UOTP 4FXGG 2XWBF 2MCYA 3OP8A 2V8EA 4F4OC 4AYMA 2IZ3A 2YBYA 4IGDA 4ONTD 5JPMG 3L89M 2EHFA 4B2SA 1VVDA 1FBRA 4DJZA 1SS2A 1QGBA 2RLQA 3ERBA 1TPGA 2RKYA 2IZ4A 3T5OA 3EJHA 4PZ5A 1Q3XA 4B2RA 1ELVA 2WIIC 3TVJA 5HYPA 2BZMA 1C1ZA 3ZRZA 4JHSA 2A55A 4C16A 1TPNA 4K12A 2ERJA 1Z92B 1U5MA 2XWJI 2RKZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J38 B;  1VVC A;  2CG7 A;  1GKG A;  2B5I D;  2W81 A;  3KXV A;  5I0Q B;  3GOV A;  2XRD A;  3O8E B;  2UWN A;  3GXE A;  2QY0 A;  3CAL A;  1E8B A;  1OK1 A;  1OK9 A;  3R62 A;  2RLP A;  2RL0 A;  2G7I A;  3OED C;  4AYE A;  3M7P A;  5HYT B;  1H2Q P;  2O39 C;  3IX0 A;  2MCZ A;  4LOT A;  1NWV A;  4ZH1 D;  4KKD A;  3KZJ A;  2CKU A;  2XRB A;  1H2P P;  3OXU D;  2JGW A;  3NFP I;  2XQW C;  1PPQ A;  4AYD A;  5HZP B;  1G4F A;  2LOJ A;  1OJW A;  2KRI A;  1H04 P;  1MD7 A;  2W80 A;  4MUC A;  4A5W B;  3MQL A;  1HCC A;  3INB C;  1SRZ A;  1QUB A;  1MD8 A;  1HFI A;  2JRA A;  1OJY A;  5HYU B;  1OK3 A;  1E88 A;  1TPM A;  1GHQ B;  3SW0 X;  2KMS A;  2YRA A;  1GKN A;  3ZD2 A;  1OK2 A;  3RJ3 D;  1E5G A;  1LY2 A;  1ZJK A;  1HFH A;  5FO8 C;  1G4G A;  2JGX A;  3IU3 I;  4YNX A;  1CKL A;  1QO6 A;  1OJV A;  4AYI A;  4LOS A;  4WJG 2;  1O9A A;  1GPZ A;  4CSY A;  2CG6 A;  3ZD1 A;  2EC3 A;  1H03 P;  1UOT P;  4FXG G;  2XWB F;  2MCY A;  3OP8 A;  2V8E A;  4F4O C;  4AYM A;  2IZ3 A;  2YBY A;  4IGD A;  4ONT D;  5JPM G;  3L89 M;  2EHF A;  4B2S A;  1VVD A;  1FBR A;  4DJZ A;  1SS2 A;  1QGB A;  2RLQ A;  3ERB A;  1TPG A;  2RKY A;  2IZ4 A;  3T5O A;  3EJH A;  4PZ5 A;  1Q3X A;  4B2R A;  1ELV A;  2WII C;  3TVJ A;  5HYP A;  2BZM A;  1C1Z A;  3ZRZ A;  4JHS A;  2A55 A;  4C16 A;  1TPN A;  4K12 A;  2ERJ A;  1Z92 B;  1U5M A;  2XWJ I;  2RKZ A; 
#chains in the Genus database with same CATH topology
 4J38 B;  1VVC A;  2CG7 A;  1GKG A;  2B5I D;  2W81 A;  3KXV A;  5I0Q B;  3GOV A;  2XRD A;  3O8E B;  2UWN A;  3GXE A;  2QY0 A;  3CAL A;  1E8B A;  2X2Z A;  1OK1 A;  3WSX A;  1OK9 A;  3R62 A;  2RLP A;  2RL0 A;  2G7I A;  3FGR A;  3FGT A;  3OED C;  1RLH A;  4AYE A;  3M7P A;  5HYT B;  1H2Q P;  2O39 C;  3IX0 A;  2MCZ A;  4LOT A;  1NWV A;  4ZH1 D;  4KKD A;  3KZJ A;  2CKU A;  5DN5 A;  2XRB A;  1H2P P;  3OXU D;  2JGW A;  3ZLD A;  3NFP I;  2XQW C;  1PPQ A;  2Y8S A;  4AYD A;  5HZP B;  1G4F A;  2LOJ A;  1OJW A;  2KRI A;  1H04 P;  1MD7 A;  2W80 A;  4MUC A;  4A5W B;  3MQL A;  4PO7 A;  1HCC A;  2I2L A;  2ZYC A;  3INB C;  1SRZ A;  4YIZ A;  1QUB A;  1MD8 A;  1HFI A;  2JRA A;  1OJY A;  3F6K A;  5HYU B;  1OK3 A;  1E88 A;  1TPM A;  1GHQ B;  3SW0 X;  2KMS A;  2Y8R A;  2YRA A;  1GKN A;  3ZD2 A;  3CI0 J;  1OK2 A;  3RJ3 D;  1E5G A;  1LY2 A;  1ZJK A;  1HFH A;  5FO8 C;  1G4G A;  2JGX A;  3IU3 I;  4YNX A;  1CKL A;  1QO6 A;  1OJV A;  4AYI A;  4LOS A;  4WJG 2;  1O9A A;  1GPZ A;  4CSY A;  3ZLE A;  2CG6 A;  3ZD1 A;  2EC3 A;  1H03 P;  1UOT P;  4FXG G;  2XWB F;  3K3T A;  2MCY A;  4BWC A;  3OP8 A;  2V8E A;  4F4O C;  4AYM A;  2IZ3 A;  2YBY A;  5DN4 A;  2Y8T A;  4IGD A;  4ONT D;  5JPM G;  3L89 M;  4MSL A;  2EHF A;  4B2S A;  1VVD A;  3WSY A;  1FBR A;  4DJZ A;  1SS2 A;  1QGB A;  2RLQ A;  3ERB A;  1TPG A;  2RKY A;  2IZ4 A;  3T5O A;  3EJH A;  4PZ5 A;  1Q3X A;  4N7E A;  1ELV A;  4B2R A;  2WII C;  3TVJ A;  5HYP A;  2BZM A;  1C1Z A;  3VWO A;  3ZRZ A;  4JHS A;  3NJA A;  4APL A;  2A55 A;  4C16 A;  1TPN A;  4K12 A;  2ERJ A;  1Z92 B;  1U5M A;  2XWJ I;  2RKZ A; 
#chains in the Genus database with same CATH homology
 4J38 B;  1VVC A;  2CG7 A;  1GKG A;  2B5I D;  2W81 A;  3KXV A;  5I0Q B;  3GOV A;  2XRD A;  3O8E B;  2UWN A;  3GXE A;  2QY0 A;  3CAL A;  1E8B A;  1OK1 A;  1OK9 A;  3R62 A;  2RLP A;  2RL0 A;  2G7I A;  3OED C;  4AYE A;  3M7P A;  5HYT B;  1H2Q P;  2O39 C;  3IX0 A;  2MCZ A;  4LOT A;  1NWV A;  4ZH1 D;  4KKD A;  3KZJ A;  2CKU A;  2XRB A;  1H2P P;  3OXU D;  2JGW A;  3NFP I;  2XQW C;  1PPQ A;  4AYD A;  5HZP B;  1G4F A;  2LOJ A;  1OJW A;  2KRI A;  1H04 P;  1MD7 A;  2W80 A;  4MUC A;  4A5W B;  3MQL A;  1HCC A;  3INB C;  1SRZ A;  1QUB A;  1MD8 A;  1HFI A;  2JRA A;  1OJY A;  5HYU B;  1OK3 A;  1E88 A;  1TPM A;  1GHQ B;  3SW0 X;  2KMS A;  2YRA A;  1GKN A;  3ZD2 A;  1OK2 A;  3RJ3 D;  1E5G A;  1LY2 A;  1ZJK A;  1HFH A;  5FO8 C;  1G4G A;  2JGX A;  3IU3 I;  4YNX A;  1CKL A;  1QO6 A;  1OJV A;  4AYI A;  4LOS A;  4WJG 2;  1O9A A;  1GPZ A;  4CSY A;  2CG6 A;  3ZD1 A;  2EC3 A;  1H03 P;  1UOT P;  4FXG G;  2XWB F;  2MCY A;  3OP8 A;  2V8E A;  4F4O C;  4AYM A;  2IZ3 A;  2YBY A;  4IGD A;  4ONT D;  5JPM G;  3L89 M;  2EHF A;  4B2S A;  1VVD A;  1FBR A;  4DJZ A;  1SS2 A;  1QGB A;  2RLQ A;  3ERB A;  1TPG A;  2RKY A;  2IZ4 A;  3T5O A;  3EJH A;  4PZ5 A;  1Q3X A;  4B2R A;  1ELV A;  2WII C;  3TVJ A;  5HYP A;  2BZM A;  1C1Z A;  3ZRZ A;  4JHS A;  2A55 A;  4C16 A;  1TPN A;  4K12 A;  2ERJ A;  1Z92 B;  1U5M A;  2XWJ I;  2RKZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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