1NWVA

Solution structure of a functionally active component of decay accelerating factor
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
129
structure length
129
Chain Sequence
FRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of a functionally active fragment of decay-accelerating factor
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Homo sapiens
molecule keywords Complement decay-accelerating factor
total genus 8
structure length 129
sequence length 129
ec nomenclature
pdb deposition date 2003-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1nwvA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1nwvA01
1MD7A 4ONTD 1HFHA 3O8EB 1E8BA 3NFPI 5HZPB 2KMSA 1QGBA 2W80A 1GKGA 1OK3A 4C16A 2JRAA 1UOTP 5HYUB 1LY2A 1TPMA 3TVJA 2KRIA 1OJYA 2BZMA 3OP8A 2CG6A 5FO8C 2MCYA 4FXGG 2XWBF 2B5ID 5HYPA 2CKUA 1VVCA 3KXVA 4IGDA 4MUCA 1OJWA 4AYMA 1OK2A 1Z92B 1OK9A 1HFIA 5HYTB 1VVDA 4AYIA 4B2RA 1GKNA 5I0QB 2UWNA 3MQLA 3T5OA 3R62A 3GXEA 3OEDC 1G4GA 4LOTA 3ZD1A 1H04P 2EC3A 4K12A 1CKLA 1Q3XA 4B2SA 3GOVA 1E88A 1H03P 1OJVA 1FBRA 1MD8A 2W81A 2XWJI 1H2QP 2XRBA 3IU3I 1GHQB 4AYDA 1ELVA 5JPMG 4CSYA 1U5MA 3ZD2A 2RL0A 2YBYA 4DJZA 2RLPA 3L89M 1HCCA 4ZH1D 2LOJA 1TPNA 2YRAA 3M7PA 4AYEA 2O39C 1C1ZA 3KZJA 3INBC 1QUBA 3ZRZA 1G4FA 2RKZA 2WIIC 4J38B 2G7IA 4PZ5A 2ERJA 1E5GA 4KKDA 4YNXA 1PPQA 2EHFA 4A5WB 2XRDA 2IZ3A 4WJG2 1QO6A 1TPGA 2MCZA 3CALA 1NWVA 1OK1A 2V8EA 2QY0A 3RJ3D 2RLQA 1H2PP 2JGWA 2CG7A 2A55A 3ERBA 1ZJKA 4F4OC 1GPZA 2JGXA 3EJHA 2XQWC 4LOSA 3OXUD 1SS2A 1SRZA 4JHSA 2RKYA 1O9AA 3IX0A 2IZ4A 3SW0X
chains in the Genus database with same CATH superfamily
1MD7A 5DN4A 4ONTD 1HFHA 3O8EB 1E8BA 3NFPI 5HZPB 2KMSA 1QGBA 2W80A 1GKGA 1OK3A 4C16A 2JRAA 1UOTP 2I2LA 5HYUB 1LY2A 1TPMA 3TVJA 2KRIA 1OJYA 2BZMA 3OP8A 2CG6A 5FO8C 2MCYA 4FXGG 2XWBF 3WSYA 2B5ID 5HYPA 2CKUA 1VVCA 3KXVA 4IGDA 4MUCA 1OJWA 2Y8TA 4AYMA 1OK2A 1Z92B 1OK9A 1HFIA 5HYTB 1VVDA 3NJAA 4AYIA 4B2RA 1GKNA 5I0QB 2UWNA 3MQLA 4PO7A 3K3TA 3T5OA 3R62A 3GXEA 3OEDC 5DN5A 4BWCA 1G4GA 4LOTA 3ZD1A 1H04P 2EC3A 4K12A 3F6KA 1CKLA 3FGRA 1Q3XA 4B2SA 3GOVA 1RLHA 1E88A 1H03P 1OJVA 1FBRA 1MD8A 3ZLEA 2W81A 2XWJI 1H2QP 3VWOA 2XRBA 3IU3I 1GHQB 4AYDA 3ZLDA 1ELVA 4YIZA 5JPMG 2X2ZA 4CSYA 1U5MA 3ZD2A 2RL0A 2YBYA 4DJZA 2RLPA 2Y8RA 3L89M 1HCCA 3WSXA 4ZH1D 2LOJA 1TPNA 2YRAA 3M7PA 4AYEA 2O39C 1C1ZA 3KZJA 3INBC 1QUBA 3ZRZA 1G4FA 2RKZA 2WIIC 4APLA 4J38B 2G7IA 2ZYCA 4PZ5A 2ERJA 1E5GA 4KKDA 4YNXA 1PPQA 2EHFA 4A5WB 2XRDA 2IZ3A 2Y8SA 4WJG2 1QO6A 1TPGA 2MCZA 3CALA 1NWVA 1OK1A 2V8EA 2QY0A 3RJ3D 3FGTA 2RLQA 1H2PP 2JGWA 2CG7A 2A55A 3ERBA 1ZJKA 4N7EA 4F4OC 3CI0J 1GPZA 2JGXA 3EJHA 2XQWC 4LOSA 3OXUD 1SS2A 1SRZA 4MSLA 4JHSA 2RKYA 1O9AA 3IX0A 2IZ4A 3SW0X
chains in the Genus database with same CATH topology
1MD7A 4ONTD 1HFHA 3O8EB 1E8BA 3NFPI 5HZPB 2KMSA 1QGBA 2W80A 1GKGA 1OK3A 4C16A 2JRAA 1UOTP 5HYUB 1LY2A 1TPMA 3TVJA 2KRIA 1OJYA 2BZMA 3OP8A 2CG6A 5FO8C 2MCYA 4FXGG 2XWBF 2B5ID 5HYPA 2CKUA 1VVCA 3KXVA 4IGDA 4MUCA 1OJWA 4AYMA 1OK2A 1Z92B 1OK9A 1HFIA 5HYTB 1VVDA 4AYIA 4B2RA 1GKNA 5I0QB 2UWNA 3MQLA 3T5OA 3R62A 3GXEA 3OEDC 1G4GA 4LOTA 3ZD1A 1H04P 2EC3A 4K12A 1CKLA 1Q3XA 4B2SA 3GOVA 1E88A 1H03P 1OJVA 1FBRA 1MD8A 2W81A 2XWJI 1H2QP 2XRBA 3IU3I 1GHQB 4AYDA 1ELVA 5JPMG 4CSYA 1U5MA 3ZD2A 2RL0A 2YBYA 4DJZA 2RLPA 3L89M 1HCCA 4ZH1D 2LOJA 1TPNA 2YRAA 3M7PA 4AYEA 2O39C 1C1ZA 3KZJA 3INBC 1QUBA 3ZRZA 1G4FA 2RKZA 2WIIC 4J38B 2G7IA 4PZ5A 2ERJA 1E5GA 4KKDA 4YNXA 1PPQA 2EHFA 4A5WB 2XRDA 2IZ3A 4WJG2 1QO6A 1TPGA 2MCZA 3CALA 1NWVA 1OK1A 2V8EA 2QY0A 3RJ3D 2RLQA 1H2PP 2JGWA 2CG7A 2A55A 3ERBA 1ZJKA 4F4OC 1GPZA 2JGXA 3EJHA 2XQWC 4LOSA 3OXUD 1SS2A 1SRZA 4JHSA 2RKYA 1O9AA 3IX0A 2IZ4A 3SW0X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MD7 A;  4ONT D;  1HFH A;  3O8E B;  1E8B A;  3NFP I;  5HZP B;  2KMS A;  1QGB A;  2W80 A;  1GKG A;  1OK3 A;  4C16 A;  2JRA A;  1UOT P;  5HYU B;  1LY2 A;  1TPM A;  3TVJ A;  2KRI A;  1OJY A;  2BZM A;  3OP8 A;  2CG6 A;  5FO8 C;  2MCY A;  4FXG G;  2XWB F;  2B5I D;  5HYP A;  2CKU A;  1VVC A;  3KXV A;  4IGD A;  4MUC A;  1OJW A;  4AYM A;  1OK2 A;  1Z92 B;  1OK9 A;  1HFI A;  5HYT B;  1VVD A;  4AYI A;  4B2R A;  1GKN A;  5I0Q B;  2UWN A;  3MQL A;  3T5O A;  3R62 A;  3GXE A;  3OED C;  1G4G A;  4LOT A;  3ZD1 A;  1H04 P;  2EC3 A;  4K12 A;  1CKL A;  1Q3X A;  4B2S A;  3GOV A;  1E88 A;  1H03 P;  1OJV A;  1FBR A;  1MD8 A;  2W81 A;  2XWJ I;  1H2Q P;  2XRB A;  3IU3 I;  1GHQ B;  4AYD A;  1ELV A;  5JPM G;  4CSY A;  1U5M A;  3ZD2 A;  2RL0 A;  2YBY A;  4DJZ A;  2RLP A;  3L89 M;  1HCC A;  4ZH1 D;  2LOJ A;  1TPN A;  2YRA A;  3M7P A;  4AYE A;  2O39 C;  1C1Z A;  3KZJ A;  3INB C;  1QUB A;  3ZRZ A;  1G4F A;  2RKZ A;  2WII C;  4J38 B;  2G7I A;  4PZ5 A;  2ERJ A;  1E5G A;  4KKD A;  4YNX A;  1PPQ A;  2EHF A;  4A5W B;  2XRD A;  2IZ3 A;  4WJG 2;  1QO6 A;  1TPG A;  2MCZ A;  3CAL A;  1NWV A;  1OK1 A;  2V8E A;  2QY0 A;  3RJ3 D;  2RLQ A;  1H2P P;  2JGW A;  2CG7 A;  2A55 A;  3ERB A;  1ZJK A;  4F4O C;  1GPZ A;  2JGX A;  3EJH A;  2XQW C;  4LOS A;  3OXU D;  1SS2 A;  1SRZ A;  4JHS A;  2RKY A;  1O9A A;  3IX0 A;  2IZ4 A;  3SW0 X; 
#chains in the Genus database with same CATH topology
 1MD7 A;  5DN4 A;  4ONT D;  1HFH A;  3O8E B;  1E8B A;  3NFP I;  5HZP B;  2KMS A;  1QGB A;  2W80 A;  1GKG A;  1OK3 A;  4C16 A;  2JRA A;  1UOT P;  2I2L A;  5HYU B;  1LY2 A;  1TPM A;  3TVJ A;  2KRI A;  1OJY A;  2BZM A;  3OP8 A;  2CG6 A;  5FO8 C;  2MCY A;  4FXG G;  2XWB F;  3WSY A;  2B5I D;  5HYP A;  2CKU A;  1VVC A;  3KXV A;  4IGD A;  4MUC A;  1OJW A;  2Y8T A;  4AYM A;  1OK2 A;  1Z92 B;  1OK9 A;  1HFI A;  5HYT B;  1VVD A;  3NJA A;  4AYI A;  4B2R A;  1GKN A;  5I0Q B;  2UWN A;  3MQL A;  4PO7 A;  3K3T A;  3T5O A;  3R62 A;  3GXE A;  3OED C;  5DN5 A;  4BWC A;  1G4G A;  4LOT A;  3ZD1 A;  1H04 P;  2EC3 A;  4K12 A;  3F6K A;  1CKL A;  3FGR A;  1Q3X A;  4B2S A;  3GOV A;  1RLH A;  1E88 A;  1H03 P;  1OJV A;  1FBR A;  1MD8 A;  3ZLE A;  2W81 A;  2XWJ I;  1H2Q P;  3VWO A;  2XRB A;  3IU3 I;  1GHQ B;  4AYD A;  3ZLD A;  1ELV A;  4YIZ A;  5JPM G;  2X2Z A;  4CSY A;  1U5M A;  3ZD2 A;  2RL0 A;  2YBY A;  4DJZ A;  2RLP A;  2Y8R A;  3L89 M;  1HCC A;  3WSX A;  4ZH1 D;  2LOJ A;  1TPN A;  2YRA A;  3M7P A;  4AYE A;  2O39 C;  1C1Z A;  3KZJ A;  3INB C;  1QUB A;  3ZRZ A;  1G4F A;  2RKZ A;  2WII C;  4APL A;  4J38 B;  2G7I A;  2ZYC A;  4PZ5 A;  2ERJ A;  1E5G A;  4KKD A;  4YNX A;  1PPQ A;  2EHF A;  4A5W B;  2XRD A;  2IZ3 A;  2Y8S A;  4WJG 2;  1QO6 A;  1TPG A;  2MCZ A;  3CAL A;  1NWV A;  1OK1 A;  2V8E A;  2QY0 A;  3RJ3 D;  3FGT A;  2RLQ A;  1H2P P;  2JGW A;  2CG7 A;  2A55 A;  3ERB A;  1ZJK A;  4N7E A;  4F4O C;  3CI0 J;  1GPZ A;  2JGX A;  3EJH A;  2XQW C;  4LOS A;  3OXU D;  1SS2 A;  1SRZ A;  4MSL A;  4JHS A;  2RKY A;  1O9A A;  3IX0 A;  2IZ4 A;  3SW0 X; 
#chains in the Genus database with same CATH homology
 1MD7 A;  4ONT D;  1HFH A;  3O8E B;  1E8B A;  3NFP I;  5HZP B;  2KMS A;  1QGB A;  2W80 A;  1GKG A;  1OK3 A;  4C16 A;  2JRA A;  1UOT P;  5HYU B;  1LY2 A;  1TPM A;  3TVJ A;  2KRI A;  1OJY A;  2BZM A;  3OP8 A;  2CG6 A;  5FO8 C;  2MCY A;  4FXG G;  2XWB F;  2B5I D;  5HYP A;  2CKU A;  1VVC A;  3KXV A;  4IGD A;  4MUC A;  1OJW A;  4AYM A;  1OK2 A;  1Z92 B;  1OK9 A;  1HFI A;  5HYT B;  1VVD A;  4AYI A;  4B2R A;  1GKN A;  5I0Q B;  2UWN A;  3MQL A;  3T5O A;  3R62 A;  3GXE A;  3OED C;  1G4G A;  4LOT A;  3ZD1 A;  1H04 P;  2EC3 A;  4K12 A;  1CKL A;  1Q3X A;  4B2S A;  3GOV A;  1E88 A;  1H03 P;  1OJV A;  1FBR A;  1MD8 A;  2W81 A;  2XWJ I;  1H2Q P;  2XRB A;  3IU3 I;  1GHQ B;  4AYD A;  1ELV A;  5JPM G;  4CSY A;  1U5M A;  3ZD2 A;  2RL0 A;  2YBY A;  4DJZ A;  2RLP A;  3L89 M;  1HCC A;  4ZH1 D;  2LOJ A;  1TPN A;  2YRA A;  3M7P A;  4AYE A;  2O39 C;  1C1Z A;  3KZJ A;  3INB C;  1QUB A;  3ZRZ A;  1G4F A;  2RKZ A;  2WII C;  4J38 B;  2G7I A;  4PZ5 A;  2ERJ A;  1E5G A;  4KKD A;  4YNX A;  1PPQ A;  2EHF A;  4A5W B;  2XRD A;  2IZ3 A;  4WJG 2;  1QO6 A;  1TPG A;  2MCZ A;  3CAL A;  1NWV A;  1OK1 A;  2V8E A;  2QY0 A;  3RJ3 D;  2RLQ A;  1H2P P;  2JGW A;  2CG7 A;  2A55 A;  3ERB A;  1ZJK A;  4F4O C;  1GPZ A;  2JGX A;  3EJH A;  2XQW C;  4LOS A;  3OXU D;  1SS2 A;  1SRZ A;  4JHS A;  2RKY A;  1O9A A;  3IX0 A;  2IZ4 A;  3SW0 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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