1NWVA

Solution structure of a functionally active component of decay accelerating factor
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
129
structure length
129
Chain Sequence
FRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of a functionally active fragment of decay-accelerating factor
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Homo sapiens
molecule keywords Complement decay-accelerating factor
total genus 8
structure length 129
sequence length 129
ec nomenclature
pdb deposition date 2003-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1nwvA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1nwvA01
3TVJA 1QO6A 4LOSA 3IU3I 2EHFA 4A5WB 4CSYA 3SW0X 2MCZA 1PPQA 1H2PP 1CKLA 1MD7A 2B5ID 2RLPA 3IX0A 2XRBA 3NFPI 1H03P 2IZ3A 1G4FA 1MD8A 4WJG2 3M7PA 2CG7A 4AYDA 1Z92B 4B2RA 4AYEA 1OJYA 3INBC 2LOJA 1E5GA 1TPGA 3ZRZA 2ERJA 2RLQA 3ZD1A 4YNXA 4FXGG 3GOVA 1NWVA 1G4GA 2KMSA 5HYUB 4KKDA 1GKGA 1ZJKA 3MQLA 1HCCA 1U5MA 3ZD2A 2JGXA 2CG6A 2XRDA 3O8EB 5I0QB 1OK3A 5HZPB 4DJZA 3EJHA 2CKUA 1H04P 3CALA 4MUCA 1E8BA 2RL0A 2W81A 2QY0A 2G7IA 3R62A 3OEDC 4JHSA 4ZH1D 3KXVA 1O9AA 1GHQB 2XQWC 2XWJI 2IZ4A 2JRAA 4LOTA 1OK2A 3T5OA 1VVDA 3KZJA 1QUBA 1QGBA 4K12A 3GXEA 1GPZA 1FBRA 5JPMG 4AYMA 2RKYA 2O39C 2W80A 1E88A 1GKNA 4ONTD 5FO8C 3L89M 2KRIA 4PZ5A 4IGDA 3OP8A 4B2SA 1Q3XA 1VVCA 2V8EA 1SS2A 2BZMA 2UWNA 2YBYA 4F4OC 1LY2A 1TPNA 2RKZA 2YRAA 4C16A 2JGWA 5HYPA 2WIIC 1OJVA 1UOTP 1HFIA 1HFHA 3RJ3D 1SRZA 1OK1A 3OXUD 1ELVA 2XWBF 1TPMA 4J38B 5HYTB 1H2QP 3ERBA 2MCYA 4AYIA 1C1ZA 2EC3A 2A55A 1OJWA 1OK9A
chains in the Genus database with same CATH superfamily
3TVJA 1QO6A 4LOSA 3IU3I 2EHFA 4A5WB 4CSYA 3SW0X 2MCZA 5DN5A 1PPQA 1H2PP 4PO7A 4BWCA 5DN4A 1CKLA 1MD7A 2B5ID 4APLA 3WSXA 2RLPA 3IX0A 2XRBA 3NFPI 1H03P 2IZ3A 1G4FA 2ZYCA 1MD8A 4WJG2 3M7PA 2CG7A 4AYDA 1Z92B 4MSLA 4B2RA 4AYEA 1OJYA 3INBC 2LOJA 1E5GA 1TPGA 3ZRZA 2ERJA 2RLQA 4YIZA 3ZD1A 4YNXA 4FXGG 3GOVA 1NWVA 1G4GA 2I2LA 2Y8RA 2KMSA 5HYUB 4KKDA 3NJAA 1GKGA 1ZJKA 3VWOA 3MQLA 3ZLEA 1HCCA 1U5MA 3ZD2A 2JGXA 2CG6A 2XRDA 3K3TA 2Y8SA 3O8EB 5I0QB 1OK3A 5HZPB 4DJZA 3WSYA 3EJHA 2CKUA 1H04P 3CALA 4MUCA 1E8BA 2RL0A 2X2ZA 2W81A 2QY0A 2G7IA 3F6KA 3R62A 3OEDC 4JHSA 4ZH1D 3KXVA 1O9AA 1GHQB 2XQWC 2XWJI 2IZ4A 2JRAA 2Y8TA 1OK2A 4LOTA 3T5OA 1VVDA 3KZJA 1QUBA 1QGBA 1RLHA 4K12A 3GXEA 1GPZA 1FBRA 5JPMG 4AYMA 2RKYA 2O39C 2W80A 1E88A 1GKNA 3FGTA 4ONTD 5FO8C 3FGRA 3L89M 2KRIA 4PZ5A 4IGDA 3OP8A 4B2SA 1Q3XA 1VVCA 2V8EA 1SS2A 2BZMA 2UWNA 2YBYA 4N7EA 4F4OC 1LY2A 1TPNA 2RKZA 2YRAA 4C16A 2JGWA 5HYPA 2WIIC 1OJVA 1UOTP 1HFIA 1HFHA 3ZLDA 3RJ3D 1SRZA 1OK1A 3OXUD 1ELVA 2XWBF 1TPMA 4J38B 5HYTB 1H2QP 3ERBA 2MCYA 4AYIA 1C1ZA 2EC3A 2A55A 1OJWA 3CI0J 1OK9A
chains in the Genus database with same CATH topology
3TVJA 1QO6A 4LOSA 3IU3I 2EHFA 4A5WB 4CSYA 3SW0X 2MCZA 1PPQA 1H2PP 1CKLA 1MD7A 2B5ID 2RLPA 3IX0A 2XRBA 3NFPI 1H03P 2IZ3A 1G4FA 1MD8A 4WJG2 3M7PA 2CG7A 4AYDA 1Z92B 4B2RA 4AYEA 1OJYA 3INBC 2LOJA 1E5GA 1TPGA 3ZRZA 2ERJA 2RLQA 3ZD1A 4YNXA 4FXGG 3GOVA 1NWVA 1G4GA 2KMSA 5HYUB 4KKDA 1GKGA 1ZJKA 3MQLA 1HCCA 1U5MA 3ZD2A 2JGXA 2CG6A 2XRDA 3O8EB 5I0QB 1OK3A 5HZPB 4DJZA 3EJHA 2CKUA 1H04P 3CALA 4MUCA 1E8BA 2RL0A 2W81A 2QY0A 2G7IA 3R62A 3OEDC 4JHSA 4ZH1D 3KXVA 1O9AA 1GHQB 2XQWC 2XWJI 2IZ4A 2JRAA 4LOTA 1OK2A 3T5OA 1VVDA 3KZJA 1QUBA 1QGBA 4K12A 3GXEA 1GPZA 1FBRA 5JPMG 4AYMA 2RKYA 2O39C 2W80A 1E88A 1GKNA 4ONTD 5FO8C 3L89M 2KRIA 4PZ5A 4IGDA 3OP8A 4B2SA 1Q3XA 1VVCA 2V8EA 1SS2A 2BZMA 2UWNA 2YBYA 4F4OC 1LY2A 1TPNA 2RKZA 2YRAA 4C16A 2JGWA 5HYPA 2WIIC 1OJVA 1UOTP 1HFIA 1HFHA 3RJ3D 1SRZA 1OK1A 3OXUD 1ELVA 2XWBF 1TPMA 4J38B 5HYTB 1H2QP 3ERBA 2MCYA 4AYIA 1C1ZA 2EC3A 2A55A 1OJWA 1OK9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TVJ A;  1QO6 A;  4LOS A;  3IU3 I;  2EHF A;  4A5W B;  4CSY A;  3SW0 X;  2MCZ A;  1PPQ A;  1H2P P;  1CKL A;  1MD7 A;  2B5I D;  2RLP A;  3IX0 A;  2XRB A;  3NFP I;  1H03 P;  2IZ3 A;  1G4F A;  1MD8 A;  4WJG 2;  3M7P A;  2CG7 A;  4AYD A;  1Z92 B;  4B2R A;  4AYE A;  1OJY A;  3INB C;  2LOJ A;  1E5G A;  1TPG A;  3ZRZ A;  2ERJ A;  2RLQ A;  3ZD1 A;  4YNX A;  4FXG G;  3GOV A;  1NWV A;  1G4G A;  2KMS A;  5HYU B;  4KKD A;  1GKG A;  1ZJK A;  3MQL A;  1HCC A;  1U5M A;  3ZD2 A;  2JGX A;  2CG6 A;  2XRD A;  3O8E B;  5I0Q B;  1OK3 A;  5HZP B;  4DJZ A;  3EJH A;  2CKU A;  1H04 P;  3CAL A;  4MUC A;  1E8B A;  2RL0 A;  2W81 A;  2QY0 A;  2G7I A;  3R62 A;  3OED C;  4JHS A;  4ZH1 D;  3KXV A;  1O9A A;  1GHQ B;  2XQW C;  2XWJ I;  2IZ4 A;  2JRA A;  4LOT A;  1OK2 A;  3T5O A;  1VVD A;  3KZJ A;  1QUB A;  1QGB A;  4K12 A;  3GXE A;  1GPZ A;  1FBR A;  5JPM G;  4AYM A;  2RKY A;  2O39 C;  2W80 A;  1E88 A;  1GKN A;  4ONT D;  5FO8 C;  3L89 M;  2KRI A;  4PZ5 A;  4IGD A;  3OP8 A;  4B2S A;  1Q3X A;  1VVC A;  2V8E A;  1SS2 A;  2BZM A;  2UWN A;  2YBY A;  4F4O C;  1LY2 A;  1TPN A;  2RKZ A;  2YRA A;  4C16 A;  2JGW A;  5HYP A;  2WII C;  1OJV A;  1UOT P;  1HFI A;  1HFH A;  3RJ3 D;  1SRZ A;  1OK1 A;  3OXU D;  1ELV A;  2XWB F;  1TPM A;  4J38 B;  5HYT B;  1H2Q P;  3ERB A;  2MCY A;  4AYI A;  1C1Z A;  2EC3 A;  2A55 A;  1OJW A;  1OK9 A; 
#chains in the Genus database with same CATH topology
 3TVJ A;  1QO6 A;  4LOS A;  3IU3 I;  2EHF A;  4A5W B;  4CSY A;  3SW0 X;  2MCZ A;  5DN5 A;  1PPQ A;  1H2P P;  4PO7 A;  4BWC A;  5DN4 A;  1CKL A;  1MD7 A;  2B5I D;  4APL A;  3WSX A;  2RLP A;  3IX0 A;  2XRB A;  3NFP I;  1H03 P;  2IZ3 A;  1G4F A;  2ZYC A;  1MD8 A;  4WJG 2;  3M7P A;  2CG7 A;  4AYD A;  1Z92 B;  4MSL A;  4B2R A;  4AYE A;  1OJY A;  3INB C;  2LOJ A;  1E5G A;  1TPG A;  3ZRZ A;  2ERJ A;  2RLQ A;  4YIZ A;  3ZD1 A;  4YNX A;  4FXG G;  3GOV A;  1NWV A;  1G4G A;  2I2L A;  2Y8R A;  2KMS A;  5HYU B;  4KKD A;  3NJA A;  1GKG A;  1ZJK A;  3VWO A;  3MQL A;  3ZLE A;  1HCC A;  1U5M A;  3ZD2 A;  2JGX A;  2CG6 A;  2XRD A;  3K3T A;  2Y8S A;  3O8E B;  5I0Q B;  1OK3 A;  5HZP B;  4DJZ A;  3WSY A;  3EJH A;  2CKU A;  1H04 P;  3CAL A;  4MUC A;  1E8B A;  2RL0 A;  2X2Z A;  2W81 A;  2QY0 A;  2G7I A;  3F6K A;  3R62 A;  3OED C;  4JHS A;  4ZH1 D;  3KXV A;  1O9A A;  1GHQ B;  2XQW C;  2XWJ I;  2IZ4 A;  2JRA A;  2Y8T A;  1OK2 A;  4LOT A;  3T5O A;  1VVD A;  3KZJ A;  1QUB A;  1QGB A;  1RLH A;  4K12 A;  3GXE A;  1GPZ A;  1FBR A;  5JPM G;  4AYM A;  2RKY A;  2O39 C;  2W80 A;  1E88 A;  1GKN A;  3FGT A;  4ONT D;  5FO8 C;  3FGR A;  3L89 M;  2KRI A;  4PZ5 A;  4IGD A;  3OP8 A;  4B2S A;  1Q3X A;  1VVC A;  2V8E A;  1SS2 A;  2BZM A;  2UWN A;  2YBY A;  4N7E A;  4F4O C;  1LY2 A;  1TPN A;  2RKZ A;  2YRA A;  4C16 A;  2JGW A;  5HYP A;  2WII C;  1OJV A;  1UOT P;  1HFI A;  1HFH A;  3ZLD A;  3RJ3 D;  1SRZ A;  1OK1 A;  3OXU D;  1ELV A;  2XWB F;  1TPM A;  4J38 B;  5HYT B;  1H2Q P;  3ERB A;  2MCY A;  4AYI A;  1C1Z A;  2EC3 A;  2A55 A;  1OJW A;  3CI0 J;  1OK9 A; 
#chains in the Genus database with same CATH homology
 3TVJ A;  1QO6 A;  4LOS A;  3IU3 I;  2EHF A;  4A5W B;  4CSY A;  3SW0 X;  2MCZ A;  1PPQ A;  1H2P P;  1CKL A;  1MD7 A;  2B5I D;  2RLP A;  3IX0 A;  2XRB A;  3NFP I;  1H03 P;  2IZ3 A;  1G4F A;  1MD8 A;  4WJG 2;  3M7P A;  2CG7 A;  4AYD A;  1Z92 B;  4B2R A;  4AYE A;  1OJY A;  3INB C;  2LOJ A;  1E5G A;  1TPG A;  3ZRZ A;  2ERJ A;  2RLQ A;  3ZD1 A;  4YNX A;  4FXG G;  3GOV A;  1NWV A;  1G4G A;  2KMS A;  5HYU B;  4KKD A;  1GKG A;  1ZJK A;  3MQL A;  1HCC A;  1U5M A;  3ZD2 A;  2JGX A;  2CG6 A;  2XRD A;  3O8E B;  5I0Q B;  1OK3 A;  5HZP B;  4DJZ A;  3EJH A;  2CKU A;  1H04 P;  3CAL A;  4MUC A;  1E8B A;  2RL0 A;  2W81 A;  2QY0 A;  2G7I A;  3R62 A;  3OED C;  4JHS A;  4ZH1 D;  3KXV A;  1O9A A;  1GHQ B;  2XQW C;  2XWJ I;  2IZ4 A;  2JRA A;  4LOT A;  1OK2 A;  3T5O A;  1VVD A;  3KZJ A;  1QUB A;  1QGB A;  4K12 A;  3GXE A;  1GPZ A;  1FBR A;  5JPM G;  4AYM A;  2RKY A;  2O39 C;  2W80 A;  1E88 A;  1GKN A;  4ONT D;  5FO8 C;  3L89 M;  2KRI A;  4PZ5 A;  4IGD A;  3OP8 A;  4B2S A;  1Q3X A;  1VVC A;  2V8E A;  1SS2 A;  2BZM A;  2UWN A;  2YBY A;  4F4O C;  1LY2 A;  1TPN A;  2RKZ A;  2YRA A;  4C16 A;  2JGW A;  5HYP A;  2WII C;  1OJV A;  1UOT P;  1HFI A;  1HFH A;  3RJ3 D;  1SRZ A;  1OK1 A;  3OXU D;  1ELV A;  2XWB F;  1TPM A;  4J38 B;  5HYT B;  1H2Q P;  3ERB A;  2MCY A;  4AYI A;  1C1Z A;  2EC3 A;  2A55 A;  1OJW A;  1OK9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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