1OK1A

Decay accelerating factor (cd55) : the structure of an intact human complement regulator.
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
254
structure length
254
Chain Sequence
MQDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
pubmed doi rcsb
molecule tags Regulator of complement pathway
source organism Homo sapiens
molecule keywords COMPLEMENT DECAY-ACCELERATING FACTOR
total genus 38
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A02
1LY2A 5HYPA 1E5GA 2W81A 4YNXA 4CSYA 5JPMG 1NWVA 3KZJA 2EHFA 1OK3A 2IZ3A 4B2RA 2CG7A 4K12A 1QUBA 1GKNA 4B2SA 2ERJA 5HYUB 3INBC 2XRDA 2W80A 3SW0X 2QY0A 3M7PA 1MD7A 2KRIA 2WIIC 1GPZA 1U5MA 2RLQA 2B5ID 1E8BA 1OK2A 1Q3XA 2MCZA 3L89M 2RKYA 4FXGG 5I0QB 4WJG2 2YRAA 4MUCA 4JHSA 3OEDC 1HFIA 3T5OA 1O9AA 4LOSA 1ZJKA 1UOTP 1TPMA 1ELVA 4IGDA 2RLPA 5HYTB 3RJ3D 2LOJA 3ZD2A 2XWJI 3ZD1A 3NFPI 3CALA 1OJWA 1OK1A 1CKLA 3R62A 4J38B 1QO6A 4KKDA 1G4GA 4A5WB 5HZPB 2BZMA 1FBRA 2JGXA 2XRBA 3ERBA 4F4OC 3KXVA 1HFHA 1HCCA 1GHQB 1OJYA 1OJVA 2CG6A 2JGWA 4ONTD 1E88A 1SRZA 3IU3I 1PPQA 1MD8A 2RL0A 1C1ZA 1TPNA 2IZ4A 2A55A 1G4FA 1VVDA 1Z92B 4ZH1D 1GKGA 4AYMA 1SS2A 2EC3A 3ZRZA 5FO8C 2XWBF 3EJHA 2MCYA 3OP8A 1H04P 1H2PP 1QGBA 3OXUD 4C16A 2UWNA 2G7IA 3GOVA 4AYDA 1H03P 3GXEA 2XQWC 3IX0A 2KMSA 4DJZA 1VVCA 4PZ5A 2RKZA 3TVJA 2V8EA 3MQLA 2O39C 3O8EB 1OK9A 1TPGA 4AYIA 1H2QP 4LOTA 4AYEA 2YBYA 2JRAA 2CKUA
chains in the Genus database with same CATH superfamily
3ZLEA 1LY2A 4BWCA 5HYPA 2Y8RA 1E5GA 2W81A 4YNXA 4CSYA 5JPMG 1NWVA 3KZJA 2EHFA 1OK3A 2IZ3A 4B2RA 3VWOA 2CG7A 4K12A 1QUBA 1GKNA 5DN4A 4B2SA 2ERJA 5HYUB 3INBC 2XRDA 2W80A 3K3TA 3SW0X 2QY0A 3M7PA 1MD7A 2KRIA 2WIIC 1GPZA 1U5MA 2RLQA 2B5ID 1E8BA 1OK2A 1Q3XA 2MCZA 3L89M 2RKYA 4FXGG 5I0QB 4WJG2 2YRAA 4MUCA 3CI0J 4MSLA 4JHSA 3OEDC 1HFIA 3T5OA 1O9AA 4LOSA 1ZJKA 1UOTP 1TPMA 1ELVA 4IGDA 2RLPA 5HYTB 3RJ3D 2LOJA 3ZD2A 2XWJI 3ZD1A 2I2LA 3NFPI 3CALA 4PO7A 1OJWA 1OK1A 1CKLA 3R62A 4J38B 1QO6A 4YIZA 4KKDA 3WSXA 1G4GA 4A5WB 5HZPB 2ZYCA 2BZMA 1FBRA 2JGXA 2XRBA 3ERBA 4F4OC 3KXVA 1HFHA 1HCCA 1GHQB 1OJYA 1OJVA 2CG6A 2JGWA 4ONTD 1E88A 1SRZA 3IU3I 5DN5A 1PPQA 1MD8A 2RL0A 1C1ZA 1TPNA 2IZ4A 2A55A 1G4FA 3WSYA 1VVDA 1Z92B 4N7EA 4ZH1D 1GKGA 4AYMA 1SS2A 2EC3A 3ZRZA 5FO8C 2XWBF 3EJHA 2MCYA 1RLHA 3OP8A 1H04P 1H2PP 1QGBA 3OXUD 4APLA 2UWNA 2G7IA 4C16A 3GOVA 4AYDA 1H03P 3GXEA 2XQWC 3IX0A 3ZLDA 2KMSA 4DJZA 1VVCA 4PZ5A 3FGRA 2RKZA 3TVJA 2Y8TA 2V8EA 3MQLA 2O39C 3O8EB 2Y8SA 3FGTA 2X2ZA 1OK9A 1TPGA 4AYIA 3F6KA 1H2QP 4LOTA 3NJAA 4AYEA 2YBYA 2JRAA 2CKUA
chains in the Genus database with same CATH topology
1LY2A 5HYPA 1E5GA 2W81A 4YNXA 4CSYA 5JPMG 1NWVA 3KZJA 2EHFA 1OK3A 2IZ3A 4B2RA 2CG7A 4K12A 1QUBA 1GKNA 4B2SA 2ERJA 5HYUB 3INBC 2XRDA 2W80A 3SW0X 2QY0A 3M7PA 1MD7A 2KRIA 2WIIC 1GPZA 1U5MA 2RLQA 2B5ID 1E8BA 1OK2A 1Q3XA 2MCZA 3L89M 2RKYA 4FXGG 5I0QB 4WJG2 2YRAA 4MUCA 4JHSA 3OEDC 1HFIA 3T5OA 1O9AA 4LOSA 1ZJKA 1UOTP 1TPMA 1ELVA 4IGDA 2RLPA 5HYTB 3RJ3D 2LOJA 3ZD2A 2XWJI 3ZD1A 3NFPI 3CALA 1OJWA 1OK1A 1CKLA 3R62A 4J38B 1QO6A 4KKDA 1G4GA 4A5WB 5HZPB 2BZMA 1FBRA 2JGXA 2XRBA 3ERBA 4F4OC 3KXVA 1HFHA 1HCCA 1GHQB 1OJYA 1OJVA 2CG6A 2JGWA 4ONTD 1E88A 1SRZA 3IU3I 1PPQA 1MD8A 2RL0A 1C1ZA 1TPNA 2IZ4A 2A55A 1G4FA 1VVDA 1Z92B 4ZH1D 1GKGA 4AYMA 1SS2A 2EC3A 3ZRZA 5FO8C 2XWBF 3EJHA 2MCYA 3OP8A 1H04P 1H2PP 1QGBA 3OXUD 4C16A 2UWNA 2G7IA 3GOVA 4AYDA 1H03P 3GXEA 2XQWC 3IX0A 2KMSA 4DJZA 1VVCA 4PZ5A 2RKZA 3TVJA 2V8EA 3MQLA 2O39C 3O8EB 1OK9A 1TPGA 4AYIA 1H2QP 4LOTA 4AYEA 2YBYA 2JRAA 2CKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LY2 A;  5HYP A;  1E5G A;  2W81 A;  4YNX A;  4CSY A;  5JPM G;  1NWV A;  3KZJ A;  2EHF A;  1OK3 A;  2IZ3 A;  4B2R A;  2CG7 A;  4K12 A;  1QUB A;  1GKN A;  4B2S A;  2ERJ A;  5HYU B;  3INB C;  2XRD A;  2W80 A;  3SW0 X;  2QY0 A;  3M7P A;  1MD7 A;  2KRI A;  2WII C;  1GPZ A;  1U5M A;  2RLQ A;  2B5I D;  1E8B A;  1OK2 A;  1Q3X A;  2MCZ A;  3L89 M;  2RKY A;  4FXG G;  5I0Q B;  4WJG 2;  2YRA A;  4MUC A;  4JHS A;  3OED C;  1HFI A;  3T5O A;  1O9A A;  4LOS A;  1ZJK A;  1UOT P;  1TPM A;  1ELV A;  4IGD A;  2RLP A;  5HYT B;  3RJ3 D;  2LOJ A;  3ZD2 A;  2XWJ I;  3ZD1 A;  3NFP I;  3CAL A;  1OJW A;  1OK1 A;  1CKL A;  3R62 A;  4J38 B;  1QO6 A;  4KKD A;  1G4G A;  4A5W B;  5HZP B;  2BZM A;  1FBR A;  2JGX A;  2XRB A;  3ERB A;  4F4O C;  3KXV A;  1HFH A;  1HCC A;  1GHQ B;  1OJY A;  1OJV A;  2CG6 A;  2JGW A;  4ONT D;  1E88 A;  1SRZ A;  3IU3 I;  1PPQ A;  1MD8 A;  2RL0 A;  1C1Z A;  1TPN A;  2IZ4 A;  2A55 A;  1G4F A;  1VVD A;  1Z92 B;  4ZH1 D;  1GKG A;  4AYM A;  1SS2 A;  2EC3 A;  3ZRZ A;  5FO8 C;  2XWB F;  3EJH A;  2MCY A;  3OP8 A;  1H04 P;  1H2P P;  1QGB A;  3OXU D;  4C16 A;  2UWN A;  2G7I A;  3GOV A;  4AYD A;  1H03 P;  3GXE A;  2XQW C;  3IX0 A;  2KMS A;  4DJZ A;  1VVC A;  4PZ5 A;  2RKZ A;  3TVJ A;  2V8E A;  3MQL A;  2O39 C;  3O8E B;  1OK9 A;  1TPG A;  4AYI A;  1H2Q P;  4LOT A;  4AYE A;  2YBY A;  2JRA A;  2CKU A; 
#chains in the Genus database with same CATH topology
 3ZLE A;  1LY2 A;  4BWC A;  5HYP A;  2Y8R A;  1E5G A;  2W81 A;  4YNX A;  4CSY A;  5JPM G;  1NWV A;  3KZJ A;  2EHF A;  1OK3 A;  2IZ3 A;  4B2R A;  3VWO A;  2CG7 A;  4K12 A;  1QUB A;  1GKN A;  5DN4 A;  4B2S A;  2ERJ A;  5HYU B;  3INB C;  2XRD A;  2W80 A;  3K3T A;  3SW0 X;  2QY0 A;  3M7P A;  1MD7 A;  2KRI A;  2WII C;  1GPZ A;  1U5M A;  2RLQ A;  2B5I D;  1E8B A;  1OK2 A;  1Q3X A;  2MCZ A;  3L89 M;  2RKY A;  4FXG G;  5I0Q B;  4WJG 2;  2YRA A;  4MUC A;  3CI0 J;  4MSL A;  4JHS A;  3OED C;  1HFI A;  3T5O A;  1O9A A;  4LOS A;  1ZJK A;  1UOT P;  1TPM A;  1ELV A;  4IGD A;  2RLP A;  5HYT B;  3RJ3 D;  2LOJ A;  3ZD2 A;  2XWJ I;  3ZD1 A;  2I2L A;  3NFP I;  3CAL A;  4PO7 A;  1OJW A;  1OK1 A;  1CKL A;  3R62 A;  4J38 B;  1QO6 A;  4YIZ A;  4KKD A;  3WSX A;  1G4G A;  4A5W B;  5HZP B;  2ZYC A;  2BZM A;  1FBR A;  2JGX A;  2XRB A;  3ERB A;  4F4O C;  3KXV A;  1HFH A;  1HCC A;  1GHQ B;  1OJY A;  1OJV A;  2CG6 A;  2JGW A;  4ONT D;  1E88 A;  1SRZ A;  3IU3 I;  5DN5 A;  1PPQ A;  1MD8 A;  2RL0 A;  1C1Z A;  1TPN A;  2IZ4 A;  2A55 A;  1G4F A;  3WSY A;  1VVD A;  1Z92 B;  4N7E A;  4ZH1 D;  1GKG A;  4AYM A;  1SS2 A;  2EC3 A;  3ZRZ A;  5FO8 C;  2XWB F;  3EJH A;  2MCY A;  1RLH A;  3OP8 A;  1H04 P;  1H2P P;  1QGB A;  3OXU D;  4APL A;  2UWN A;  2G7I A;  4C16 A;  3GOV A;  4AYD A;  1H03 P;  3GXE A;  2XQW C;  3IX0 A;  3ZLD A;  2KMS A;  4DJZ A;  1VVC A;  4PZ5 A;  3FGR A;  2RKZ A;  3TVJ A;  2Y8T A;  2V8E A;  3MQL A;  2O39 C;  3O8E B;  2Y8S A;  3FGT A;  2X2Z A;  1OK9 A;  1TPG A;  4AYI A;  3F6K A;  1H2Q P;  4LOT A;  3NJA A;  4AYE A;  2YBY A;  2JRA A;  2CKU A; 
#chains in the Genus database with same CATH homology
 1LY2 A;  5HYP A;  1E5G A;  2W81 A;  4YNX A;  4CSY A;  5JPM G;  1NWV A;  3KZJ A;  2EHF A;  1OK3 A;  2IZ3 A;  4B2R A;  2CG7 A;  4K12 A;  1QUB A;  1GKN A;  4B2S A;  2ERJ A;  5HYU B;  3INB C;  2XRD A;  2W80 A;  3SW0 X;  2QY0 A;  3M7P A;  1MD7 A;  2KRI A;  2WII C;  1GPZ A;  1U5M A;  2RLQ A;  2B5I D;  1E8B A;  1OK2 A;  1Q3X A;  2MCZ A;  3L89 M;  2RKY A;  4FXG G;  5I0Q B;  4WJG 2;  2YRA A;  4MUC A;  4JHS A;  3OED C;  1HFI A;  3T5O A;  1O9A A;  4LOS A;  1ZJK A;  1UOT P;  1TPM A;  1ELV A;  4IGD A;  2RLP A;  5HYT B;  3RJ3 D;  2LOJ A;  3ZD2 A;  2XWJ I;  3ZD1 A;  3NFP I;  3CAL A;  1OJW A;  1OK1 A;  1CKL A;  3R62 A;  4J38 B;  1QO6 A;  4KKD A;  1G4G A;  4A5W B;  5HZP B;  2BZM A;  1FBR A;  2JGX A;  2XRB A;  3ERB A;  4F4O C;  3KXV A;  1HFH A;  1HCC A;  1GHQ B;  1OJY A;  1OJV A;  2CG6 A;  2JGW A;  4ONT D;  1E88 A;  1SRZ A;  3IU3 I;  1PPQ A;  1MD8 A;  2RL0 A;  1C1Z A;  1TPN A;  2IZ4 A;  2A55 A;  1G4F A;  1VVD A;  1Z92 B;  4ZH1 D;  1GKG A;  4AYM A;  1SS2 A;  2EC3 A;  3ZRZ A;  5FO8 C;  2XWB F;  3EJH A;  2MCY A;  3OP8 A;  1H04 P;  1H2P P;  1QGB A;  3OXU D;  4C16 A;  2UWN A;  2G7I A;  3GOV A;  4AYD A;  1H03 P;  3GXE A;  2XQW C;  3IX0 A;  2KMS A;  4DJZ A;  1VVC A;  4PZ5 A;  2RKZ A;  3TVJ A;  2V8E A;  3MQL A;  2O39 C;  3O8E B;  1OK9 A;  1TPG A;  4AYI A;  1H2Q P;  4LOT A;  4AYE A;  2YBY A;  2JRA A;  2CKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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