1OK2A

Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
254
structure length
254
Chain Sequence
MQDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
pubmed doi rcsb
molecule tags Regulator of complement pathway
source organism Homo sapiens
molecule keywords COMPLEMENT DECAY-ACCELERATING FACTOR
total genus 35
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A02
3OEDC 1MD7A 2CG6A 3KXVA 4B2RA 2WIIC 3GOVA 1GKGA 5HZPB 1HFIA 1VVCA 3IU3I 1Z92B 4C16A 5HYPA 3KZJA 4IGDA 1SS2A 1OJYA 4CSYA 1OK1A 3SW0X 2XRBA 3MQLA 3OXUD 4ONTD 4A5WB 4AYEA 2KMSA 2LOJA 1TPNA 1H2PP 2YRAA 4J38B 2V8EA 4YNXA 2G7IA 3ZRZA 2MCYA 2BZMA 1GPZA 1HFHA 1OK3A 2CG7A 3INBC 2A55A 4LOSA 1G4FA 2MCZA 2IZ4A 1OK9A 1ZJKA 4AYMA 2QY0A 2XQWC 1ELVA 1H04P 3EJHA 3TVJA 2JGWA 1E8BA 3O8EB 2O39C 3ERBA 4WJG2 3GXEA 2JRAA 5HYTB 4FXGG 2W81A 2XRDA 2B5ID 1VVDA 4K12A 1SRZA 2IZ3A 1U5MA 1OJVA 1QGBA 4JHSA 3T5OA 4PZ5A 3M7PA 3ZD1A 4AYDA 3CALA 3L89M 3OP8A 2RL0A 1OJWA 4KKDA 5I0QB 1TPGA 4DJZA 2RKYA 2EC3A 1Q3XA 2XWBF 1H03P 2YBYA 5FO8C 1OK2A 1UOTP 2ERJA 1O9AA 2XWJI 4MUCA 2RLPA 1E88A 2JGXA 1CKLA 2CKUA 5JPMG 2UWNA 1PPQA 1MD8A 3NFPI 1FBRA 1HCCA 5HYUB 3ZD2A 3RJ3D 1C1ZA 1QUBA 1QO6A 4AYIA 3R62A 1TPMA 2KRIA 1GKNA 1E5GA 2EHFA 4ZH1D 1G4GA 2RLQA 3IX0A 1GHQB 1LY2A 4B2SA 2RKZA 1NWVA 4F4OC 4LOTA 1H2QP 2W80A
chains in the Genus database with same CATH superfamily
3OEDC 1MD7A 2CG6A 2I2LA 3KXVA 3ZLDA 4B2RA 2WIIC 3GOVA 1GKGA 3VWOA 5HZPB 1HFIA 1VVCA 3IU3I 1Z92B 4C16A 5HYPA 3KZJA 4IGDA 1SS2A 1OJYA 4CSYA 1OK1A 3SW0X 2XRBA 3MQLA 3OXUD 4ONTD 3ZLEA 4A5WB 2KMSA 2LOJA 4AYEA 1TPNA 4N7EA 1H2PP 2YRAA 2Y8TA 4J38B 2V8EA 4YNXA 2G7IA 3ZRZA 2MCYA 2BZMA 1GPZA 4BWCA 1HFHA 1OK3A 4YIZA 2CG7A 3INBC 2A55A 4LOSA 1G4FA 2MCZA 2IZ4A 1OK9A 1ZJKA 4AYMA 2QY0A 2XQWC 1ELVA 1H04P 3EJHA 3TVJA 4APLA 3FGTA 2JGWA 5DN4A 1E8BA 3O8EB 2O39C 2X2ZA 3ERBA 4WJG2 3GXEA 2JRAA 5HYTB 4FXGG 3WSXA 2W81A 4MSLA 2XRDA 2B5ID 1VVDA 4K12A 1SRZA 2IZ3A 1U5MA 1OJVA 1QGBA 4JHSA 3K3TA 4PO7A 4PZ5A 3T5OA 3M7PA 3ZD1A 4AYDA 3CALA 3L89M 3OP8A 2RL0A 1OJWA 4KKDA 5I0QB 1RLHA 2ZYCA 1TPGA 4DJZA 2RKYA 2EC3A 1Q3XA 2XWBF 1H03P 2YBYA 5FO8C 1OK2A 1UOTP 3WSYA 2ERJA 1O9AA 2XWJI 4MUCA 3F6KA 3CI0J 5DN5A 3FGRA 2RLPA 1E88A 2JGXA 1CKLA 2CKUA 5JPMG 2UWNA 1PPQA 2Y8RA 1MD8A 3NFPI 1FBRA 1HCCA 5HYUB 3ZD2A 3RJ3D 1C1ZA 1QUBA 1QO6A 4AYIA 3R62A 1TPMA 2KRIA 3NJAA 1GKNA 1E5GA 2EHFA 4ZH1D 1G4GA 2RLQA 3IX0A 2Y8SA 1GHQB 1LY2A 4B2SA 2RKZA 1NWVA 4F4OC 4LOTA 1H2QP 2W80A
chains in the Genus database with same CATH topology
3OEDC 1MD7A 2CG6A 3KXVA 4B2RA 2WIIC 3GOVA 1GKGA 5HZPB 1HFIA 1VVCA 3IU3I 1Z92B 4C16A 5HYPA 3KZJA 4IGDA 1SS2A 1OJYA 4CSYA 1OK1A 3SW0X 2XRBA 3MQLA 3OXUD 4ONTD 4A5WB 4AYEA 2KMSA 2LOJA 1TPNA 1H2PP 2YRAA 4J38B 2V8EA 4YNXA 2G7IA 3ZRZA 2MCYA 2BZMA 1GPZA 1HFHA 1OK3A 2CG7A 3INBC 2A55A 4LOSA 1G4FA 2MCZA 2IZ4A 1OK9A 1ZJKA 4AYMA 2QY0A 2XQWC 1ELVA 1H04P 3EJHA 3TVJA 2JGWA 1E8BA 3O8EB 2O39C 3ERBA 4WJG2 3GXEA 2JRAA 5HYTB 4FXGG 2W81A 2XRDA 2B5ID 1VVDA 4K12A 1SRZA 2IZ3A 1U5MA 1OJVA 1QGBA 4JHSA 3T5OA 4PZ5A 3M7PA 3ZD1A 4AYDA 3CALA 3L89M 3OP8A 2RL0A 1OJWA 4KKDA 5I0QB 1TPGA 4DJZA 2RKYA 2EC3A 1Q3XA 2XWBF 1H03P 2YBYA 5FO8C 1OK2A 1UOTP 2ERJA 1O9AA 2XWJI 4MUCA 2RLPA 1E88A 2JGXA 1CKLA 2CKUA 5JPMG 2UWNA 1PPQA 1MD8A 3NFPI 1FBRA 1HCCA 5HYUB 3ZD2A 3RJ3D 1C1ZA 1QUBA 1QO6A 4AYIA 3R62A 1TPMA 2KRIA 1GKNA 1E5GA 2EHFA 4ZH1D 1G4GA 2RLQA 3IX0A 1GHQB 1LY2A 4B2SA 2RKZA 1NWVA 4F4OC 4LOTA 1H2QP 2W80A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OED C;  1MD7 A;  2CG6 A;  3KXV A;  4B2R A;  2WII C;  3GOV A;  1GKG A;  5HZP B;  1HFI A;  1VVC A;  3IU3 I;  1Z92 B;  4C16 A;  5HYP A;  3KZJ A;  4IGD A;  1SS2 A;  1OJY A;  4CSY A;  1OK1 A;  3SW0 X;  2XRB A;  3MQL A;  3OXU D;  4ONT D;  4A5W B;  4AYE A;  2KMS A;  2LOJ A;  1TPN A;  1H2P P;  2YRA A;  4J38 B;  2V8E A;  4YNX A;  2G7I A;  3ZRZ A;  2MCY A;  2BZM A;  1GPZ A;  1HFH A;  1OK3 A;  2CG7 A;  3INB C;  2A55 A;  4LOS A;  1G4F A;  2MCZ A;  2IZ4 A;  1OK9 A;  1ZJK A;  4AYM A;  2QY0 A;  2XQW C;  1ELV A;  1H04 P;  3EJH A;  3TVJ A;  2JGW A;  1E8B A;  3O8E B;  2O39 C;  3ERB A;  4WJG 2;  3GXE A;  2JRA A;  5HYT B;  4FXG G;  2W81 A;  2XRD A;  2B5I D;  1VVD A;  4K12 A;  1SRZ A;  2IZ3 A;  1U5M A;  1OJV A;  1QGB A;  4JHS A;  3T5O A;  4PZ5 A;  3M7P A;  3ZD1 A;  4AYD A;  3CAL A;  3L89 M;  3OP8 A;  2RL0 A;  1OJW A;  4KKD A;  5I0Q B;  1TPG A;  4DJZ A;  2RKY A;  2EC3 A;  1Q3X A;  2XWB F;  1H03 P;  2YBY A;  5FO8 C;  1OK2 A;  1UOT P;  2ERJ A;  1O9A A;  2XWJ I;  4MUC A;  2RLP A;  1E88 A;  2JGX A;  1CKL A;  2CKU A;  5JPM G;  2UWN A;  1PPQ A;  1MD8 A;  3NFP I;  1FBR A;  1HCC A;  5HYU B;  3ZD2 A;  3RJ3 D;  1C1Z A;  1QUB A;  1QO6 A;  4AYI A;  3R62 A;  1TPM A;  2KRI A;  1GKN A;  1E5G A;  2EHF A;  4ZH1 D;  1G4G A;  2RLQ A;  3IX0 A;  1GHQ B;  1LY2 A;  4B2S A;  2RKZ A;  1NWV A;  4F4O C;  4LOT A;  1H2Q P;  2W80 A; 
#chains in the Genus database with same CATH topology
 3OED C;  1MD7 A;  2CG6 A;  2I2L A;  3KXV A;  3ZLD A;  4B2R A;  2WII C;  3GOV A;  1GKG A;  3VWO A;  5HZP B;  1HFI A;  1VVC A;  3IU3 I;  1Z92 B;  4C16 A;  5HYP A;  3KZJ A;  4IGD A;  1SS2 A;  1OJY A;  4CSY A;  1OK1 A;  3SW0 X;  2XRB A;  3MQL A;  3OXU D;  4ONT D;  3ZLE A;  4A5W B;  2KMS A;  2LOJ A;  4AYE A;  1TPN A;  4N7E A;  1H2P P;  2YRA A;  2Y8T A;  4J38 B;  2V8E A;  4YNX A;  2G7I A;  3ZRZ A;  2MCY A;  2BZM A;  1GPZ A;  4BWC A;  1HFH A;  1OK3 A;  4YIZ A;  2CG7 A;  3INB C;  2A55 A;  4LOS A;  1G4F A;  2MCZ A;  2IZ4 A;  1OK9 A;  1ZJK A;  4AYM A;  2QY0 A;  2XQW C;  1ELV A;  1H04 P;  3EJH A;  3TVJ A;  4APL A;  3FGT A;  2JGW A;  5DN4 A;  1E8B A;  3O8E B;  2O39 C;  2X2Z A;  3ERB A;  4WJG 2;  3GXE A;  2JRA A;  5HYT B;  4FXG G;  3WSX A;  2W81 A;  4MSL A;  2XRD A;  2B5I D;  1VVD A;  4K12 A;  1SRZ A;  2IZ3 A;  1U5M A;  1OJV A;  1QGB A;  4JHS A;  3K3T A;  4PO7 A;  4PZ5 A;  3T5O A;  3M7P A;  3ZD1 A;  4AYD A;  3CAL A;  3L89 M;  3OP8 A;  2RL0 A;  1OJW A;  4KKD A;  5I0Q B;  1RLH A;  2ZYC A;  1TPG A;  4DJZ A;  2RKY A;  2EC3 A;  1Q3X A;  2XWB F;  1H03 P;  2YBY A;  5FO8 C;  1OK2 A;  1UOT P;  3WSY A;  2ERJ A;  1O9A A;  2XWJ I;  4MUC A;  3F6K A;  3CI0 J;  5DN5 A;  3FGR A;  2RLP A;  1E88 A;  2JGX A;  1CKL A;  2CKU A;  5JPM G;  2UWN A;  1PPQ A;  2Y8R A;  1MD8 A;  3NFP I;  1FBR A;  1HCC A;  5HYU B;  3ZD2 A;  3RJ3 D;  1C1Z A;  1QUB A;  1QO6 A;  4AYI A;  3R62 A;  1TPM A;  2KRI A;  3NJA A;  1GKN A;  1E5G A;  2EHF A;  4ZH1 D;  1G4G A;  2RLQ A;  3IX0 A;  2Y8S A;  1GHQ B;  1LY2 A;  4B2S A;  2RKZ A;  1NWV A;  4F4O C;  4LOT A;  1H2Q P;  2W80 A; 
#chains in the Genus database with same CATH homology
 3OED C;  1MD7 A;  2CG6 A;  3KXV A;  4B2R A;  2WII C;  3GOV A;  1GKG A;  5HZP B;  1HFI A;  1VVC A;  3IU3 I;  1Z92 B;  4C16 A;  5HYP A;  3KZJ A;  4IGD A;  1SS2 A;  1OJY A;  4CSY A;  1OK1 A;  3SW0 X;  2XRB A;  3MQL A;  3OXU D;  4ONT D;  4A5W B;  4AYE A;  2KMS A;  2LOJ A;  1TPN A;  1H2P P;  2YRA A;  4J38 B;  2V8E A;  4YNX A;  2G7I A;  3ZRZ A;  2MCY A;  2BZM A;  1GPZ A;  1HFH A;  1OK3 A;  2CG7 A;  3INB C;  2A55 A;  4LOS A;  1G4F A;  2MCZ A;  2IZ4 A;  1OK9 A;  1ZJK A;  4AYM A;  2QY0 A;  2XQW C;  1ELV A;  1H04 P;  3EJH A;  3TVJ A;  2JGW A;  1E8B A;  3O8E B;  2O39 C;  3ERB A;  4WJG 2;  3GXE A;  2JRA A;  5HYT B;  4FXG G;  2W81 A;  2XRD A;  2B5I D;  1VVD A;  4K12 A;  1SRZ A;  2IZ3 A;  1U5M A;  1OJV A;  1QGB A;  4JHS A;  3T5O A;  4PZ5 A;  3M7P A;  3ZD1 A;  4AYD A;  3CAL A;  3L89 M;  3OP8 A;  2RL0 A;  1OJW A;  4KKD A;  5I0Q B;  1TPG A;  4DJZ A;  2RKY A;  2EC3 A;  1Q3X A;  2XWB F;  1H03 P;  2YBY A;  5FO8 C;  1OK2 A;  1UOT P;  2ERJ A;  1O9A A;  2XWJ I;  4MUC A;  2RLP A;  1E88 A;  2JGX A;  1CKL A;  2CKU A;  5JPM G;  2UWN A;  1PPQ A;  1MD8 A;  3NFP I;  1FBR A;  1HCC A;  5HYU B;  3ZD2 A;  3RJ3 D;  1C1Z A;  1QUB A;  1QO6 A;  4AYI A;  3R62 A;  1TPM A;  2KRI A;  1GKN A;  1E5G A;  2EHF A;  4ZH1 D;  1G4G A;  2RLQ A;  3IX0 A;  1GHQ B;  1LY2 A;  4B2S A;  2RKZ A;  1NWV A;  4F4O C;  4LOT A;  1H2Q P;  2W80 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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